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Conserved domains on  [gi|564349915|ref|XP_006237783|]
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junctophilin-1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642   93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642  167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642  214 --------ADGDR------------------------------------------------------------------- 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642  219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                        330
                 ....*....|.
gi 564349915 323 DGSKEEGKYKN 333
Cdd:COG4642  261 DGSVYEGEWKN 271
PspC_subgroup_2 super family cl41463
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


The actual alignment was detected with superfamily member NF033839:

Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839 308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839 386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564349915 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839 456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642   93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642  167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642  214 --------ADGDR------------------------------------------------------------------- 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642  219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                        330
                 ....*....|.
gi 564349915 323 DGSKEEGKYKN 333
Cdd:COG4642  261 DGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.92e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.14  E-value: 1.92e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564349915  81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 8.85e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 8.85e-05
                          10        20
                  ....*....|....*....|...
gi 564349915  304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839 308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839 386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564349915 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839 456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.68e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.68e-04
                           10        20
                   ....*....|....*....|.
gi 564349915   303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642   93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642  167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642  214 --------ADGDR------------------------------------------------------------------- 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642  219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                        330
                 ....*....|.
gi 564349915 323 DGSKEEGKYKN 333
Cdd:COG4642  261 DGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.77e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.42  E-value: 1.77e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   2 TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGqGEYSGSWSHG-FEVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKW 80
Cdd:COG4642  138 GGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHG-----QGTY 211

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564349915  81 MyrgeWSHGFkgrygvrqslctpaRYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:COG4642  212 T----YADGD--------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.92e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.14  E-value: 1.92e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185  24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564349915  81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185 101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
9-336 6.96e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 90.02  E-value: 6.96e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915   9 DDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWM-YRGEWS 87
Cdd:COG4642   41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGgGGGVLE 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  88 HGFKGRYGVRQS--------LCTPA---RYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQsvpygmatvir 156
Cdd:COG4642  121 GDDGGGYGGGTAdggrggggIYTFPngdVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----------- 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 157 splrtslaslrseQSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskr 236
Cdd:COG4642  190 -------------YANGDV------------------------------------------------------------- 195

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 237 ssvrsdaamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGY 316
Cdd:COG4642  196 --------------------------------------------YEGEFKNGQRHGQGTYTYADGDRYEGEFKNGKRHGQ 231

                        330       340
                 ....*....|....*....|
gi 564349915 317 GCTVFPDGSKEEGKYKNNIL 336
Cdd:COG4642  232 GTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-150 1.17e-10

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 64.85  E-value: 1.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  38 YSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKWMyrgeWSHGfkgrygvrqslctpARYEGTWSNGLQD 116
Cdd:PLN03185  11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHG-----NGKIS----WPSG--------------ATYEGEFSGGYMH 67

                         90       100       110
                 ....*....|....*....|....*....|....
gi 564349915 117 GYGVETYGDGGTYQGQWAGGMRHGYGvRQSVPYG 150
Cdd:PLN03185  68 GSGTYTGTDGTTYKGRWRLNLKHGLG-YQRYPNG 100
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-325 1.75e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 1.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGvrqsvpygmatVIRSPlrtSLASLRSEQSNGsVLHEAAAAAAD 185
Cdd:PLN03185  11 YSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-----------KISWP---SGATYEGEFSGG-YMHGSGTYTGT 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 186 NPAGTRGGFVLNFhadtelgkkKSGLFRRGSLLGSMklrkseskssisskrssvRSDAAMSRISSSDANSTISFGDVdcd 265
Cdd:PLN03185  76 DGTTYKGRWRLNL---------KHGLGYQRYPNGDV------------------FEGSWIQGLQEGPGKYTWANGNV--- 125

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 266 fcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGS 325
Cdd:PLN03185 126 ---------------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 5.17e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 44.29  E-value: 5.17e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564349915 283 GEWKNDKRNGFGISERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849   83 GTYKNGKLEGEWKEYYENGkLKSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKD 139
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 8.85e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 8.85e-05
                          10        20
                  ....*....|....*....|...
gi 564349915  304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-332 1.97e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.82  E-value: 1.97e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564349915 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
Cdd:PLN03185  56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWI 108
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839 308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839 386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564349915 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839 456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 3.01e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.16  E-value: 3.01e-04
                          10        20
                  ....*....|....*....|...
gi 564349915  106 YEGTWSNGLQDGYGVETYGDGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.68e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.68e-04
                           10        20
                   ....*....|....*....|.
gi 564349915   303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-335 1.02e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.51  E-value: 1.02e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564349915 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Cdd:PLN03185  33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 1.04e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 40.44  E-value: 1.04e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 564349915 283 GEWKNDKRNGFGISERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849  107 GNYKNGKLHGEWKEYYENGkLKEEGNYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 279-331 1.33e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.13  E-value: 1.33e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564349915 279 ETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Cdd:PLN03185   9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEF 61
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 55-142 1.66e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 41.74  E-value: 1.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564349915  55 PSGNTYQGYWaqgkrHGLGVETKGKWMyrgeWSHGfkgrygvrqslCTparYEGTWSNGLQDGYGVETYGDGGTYQGQWA 134
Cdd:PLN03185   6 SNGDFYSGSL-----LGNVPEGPGKYL----WSDG-----------CM---YEGEWRRGMRHGNGKISWPSGATYEGEFS 62


                 ....*...
gi 564349915 135 GGMRHGYG 142
Cdd:PLN03185  63 GGYMHGSG 70
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 9.98e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 33.85  E-value: 9.98e-03
                           10        20
                   ....*....|....*....|..
gi 564349915   104 ARYEGTWSNGLQDGYGVETYGD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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