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Conserved domains on  [gi|672060362|ref|XP_006242103|]
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protein phosphatase 1 regulatory subunit 29 [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 1.08e-16

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886  118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672060362 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886  194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 1.08e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886  118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672060362 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886  194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
LRR_8 pfam13855
Leucine rich repeat;
80-139 3.12e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.85  E-value: 3.12e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362   80 NLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 157-227 3.25e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 54.32  E-value: 3.25e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672060362   157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLL 71
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 60-187 1.12e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.17  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKA-----------VLY---------SSLNRFGNLTDLNLTKNEISYIEDgaFLGQTSLQVLQLGYNR----- 114
Cdd:cd21340    7 LYLNDKNITKidnlslcknlkVLYlydnkitkiENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRisvve 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362 115 ----LSNLTE------------------GMLRGMSR-LQFLFVQHNLIEVVTPtaFSECPSLISIDLSSNRLSRLD--GA 169
Cdd:cd21340   85 glenLTNLEElhienqrlppgekltfdpRSLAALSNsLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLD 162

                        170
                 ....*....|....*...
gi 672060362 170 TFASLASLMVCELAGNPF 187
Cdd:cd21340  163 LLSSWPSLRELDLTGNPV 180
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-188 2.08e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.22  E-value: 2.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAVLYSSLnRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 457 LSLARNKFFGGLPDSF-GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQL 535

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 672060362 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLH 584
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-205 1.08e-16

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 83.44  E-value: 1.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886  118 LDLSGNQLTD-LPEELANLTNLKELDLSNNQLTDL--PEPLGNlTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672060362 139 IEVVtPTAFSECPSLISIDLSSNRLSRLDgATFASLASLMVCELAGNPFNCECDLFGF--LAWLVVFNN 205
Cdd:COG4886  194 ITDL-PEPLGNLTNLEELDLSGNQLTDLP-EPLANLTNLETLDLSNNQLTDLPELGNLtnLEELDLSNN 260
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
60-214 1.61e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.51  E-value: 1.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKaVLYSSLNRFGNLTDLNLTKNEISYIedGAFLGQ-TSLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNL 138
Cdd:COG4886  164 LDLSNNQLT-DLPEELGNLTNLKELDLSNNQITDL--PEPLGNlTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQ 239

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672060362 139 IEVVTptAFSECPSLISIDLSSNRLSRLDgaTFASLASLMVCELAGNPFNcECDLFGFLAWLVVFNNVTKNYDRLQ 214
Cdd:COG4886  240 LTDLP--ELGNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQLT-DLKLKELELLLGLNSLLLLLLLLNL 310
LRR_8 pfam13855
Leucine rich repeat;
80-139 3.12e-13

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 64.85  E-value: 3.12e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362   80 NLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
39-197 2.32e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.50  E-value: 2.32e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  39 CSQNQppYETIPQHINSTVH--DLRLNENKLKAvLYSSLNRFGNLTDLNLTKNEISYIEDGafLGQ-TSLQVLQLGYNRL 115
Cdd:COG4886  166 LSNNQ--LTDLPEELGNLTNlkELDLSNNQITD-LPEPLGNLTNLEELDLSGNQLTDLPEP--LANlTNLETLDLSNNQL 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362 116 SNLTEgmLRGMSRLQFLFVQHNLIEVVTPTAfsECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFG 195
Cdd:COG4886  241 TDLPE--LGNLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLIL 316


                 ..
gi 672060362 196 FL 197
Cdd:COG4886  317 LL 318
LRR_8 pfam13855
Leucine rich repeat;
103-163 7.93e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 57.92  E-value: 7.93e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672060362  103 TSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRL 163
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-188 9.57e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 64.57  E-value: 9.57e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  40 SQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKN-EISYIED--------------GAFLGQ-T 103
Cdd:COG4886   57 LRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNeELSNLTNlesldlsgnqltdlPEELANlT 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362 104 SLQVLQLGYNRLSNLTEGmLRGMSRLQFLFVQHNLIEVVtPTAFSECPSLISIDLSSNRLSRLdGATFASLASLMVCELA 183
Cdd:COG4886  137 NLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLS 213


                 ....*
gi 672060362 184 GNPFN 188
Cdd:COG4886  214 GNQLT 218
LRR_8 pfam13855
Leucine rich repeat;
127-187 1.26e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 54.84  E-value: 1.26e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672060362  127 SRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPF 187
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 157-227 3.25e-07

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 54.32  E-value: 3.25e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672060362   157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLL 71
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 60-187 1.12e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.17  E-value: 1.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKA-----------VLY---------SSLNRFGNLTDLNLTKNEISYIEDgaFLGQTSLQVLQLGYNR----- 114
Cdd:cd21340    7 LYLNDKNITKidnlslcknlkVLYlydnkitkiENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRisvve 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362 115 ----LSNLTE------------------GMLRGMSR-LQFLFVQHNLIEVVTPtaFSECPSLISIDLSSNRLSRLD--GA 169
Cdd:cd21340   85 glenLTNLEElhienqrlppgekltfdpRSLAALSNsLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLD 162

                        170
                 ....*....|....*...
gi 672060362 170 TFASLASLMVCELAGNPF 187
Cdd:cd21340  163 LLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
55-115 1.29e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.36  E-value: 1.29e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672060362   55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRL 115
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 75-165 9.14e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 44.39  E-value: 9.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  75 LNRFGNLTDLNLTKNEIS--------------YIED-----G---AFLGQT------SLQVLQLGYNRLSNLTEgmLRGM 126
Cdd:cd21340   64 LENLVNLKKLYLGGNRISvveglenltnleelHIENqrlppGeklTFDPRSlaalsnSLRVLNISGNNIDSLEP--LAPL 141

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 672060362 127 SRLQFLFVQHNLIEVVTPTA--FSECPSLISIDLSSNRLSR 165
Cdd:cd21340  142 RNLEQLDASNNQISDLEELLdlLSSWPSLRELDLTGNPVCK 182
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-188 2.08e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 45.22  E-value: 2.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAVLYSSLnRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 457 LSLARNKFFGGLPDSF-GSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQL 535

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 672060362 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
Cdd:PLN00113 536 SGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLH 584
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-187 2.14e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 2.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYiEDGAFLGQ-TSLQVLQLGYNRLSNLTEGMLRGMSRLQFLFVQHNL 138
Cdd:PLN00113 193 LTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSG-EIPYEIGGlTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNK 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 672060362 139 IEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPF 187
Cdd:PLN00113 272 LSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNF 320
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 60-228 7.52e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.30  E-value: 7.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLS-NLTEgmLRGMSRLQFLFVQHNL 138
Cdd:PLN00113 409 VRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFgGLPD--SFGSKRLENLDLSRNQ 486

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362 139 IEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLfGFlAWLVVFNNVTKNYDRLQCESP 218
Cdd:PLN00113 487 FSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPA-SF-SEMPVLSQLDLSQNQLSGEIP 564

                        170
                 ....*....|
gi 672060362 219 REFAGYPLLV 228
Cdd:PLN00113 565 KNLGNVESLV 574
PLN03150 PLN03150
hypothetical protein; Provisional
 39-146 1.37e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.11  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  39 CSQNQPPYETIPQHINST-----VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYN 113
Cdd:PLN03150 397 CVPQQHPWSGADCQFDSTkgkwfIDGLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYN 476

                         90       100       110
                 ....*....|....*....|....*....|...
gi 672060362 114 RLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTA 146
Cdd:PLN03150 477 SFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
 80-161 3.73e-03

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 38.29  E-value: 3.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362   80 NLTDLNLTKNeISYIEDGAFLGQTSLQVLQLGynrlSNLTE-GmlrgmsrlQFLFVQHNLIEVVTPT--------AFSEC 150
Cdd:pfam13306  12 SLTSITIPSS-LTSIGEYAFSNCTSLKSITLP----SSLTSiG--------SYAFYNCSLTSITIPSsltsigeyAFSNC 78

                          90
                  ....*....|.
gi 672060362  151 PSLISIDLSSN 161
Cdd:pfam13306  79 SNLKSITLPSN 89
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 54-164 5.62e-03

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 40.16  E-value: 5.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  54 NSTVHDLRLNENKLK----AVLYSSLNRFGNLTDLNLTKNEISyiEDGAFL------GQTSLQVLQLGYNRLS-----NL 118
Cdd:COG5238  235 NKSLTTLDLSNNQIGdegvIALAEALKNNTTVETLYLSGNQIG--AEGAIAlakalqGNTTLTSLDLSVNRIGdegaiAL 312

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 672060362 119 TEGmLRGMSRLQFLFVQHNLIEVV----TPTAFSECPSLISIDLSSNRLS 164
Cdd:COG5238  313 AEG-LQGNKTLHTLNLAYNGIGAQgaiaLAKALQENTTLHSLDLSDNQIG 361
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 40-139 9.32e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 9.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672060362  40 SQNQPPyETIPQHIN--STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQTSLQVLQLGYNRLSN 117
Cdd:PLN00113 483 SRNQFS-GAVPRKLGslSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSG 561

                         90       100
                 ....*....|....*....|..
gi 672060362 118 LTEGMLRGMSRLQFLFVQHNLI 139
Cdd:PLN00113 562 EIPKNLGNVESLVQVNISHNHL 583
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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