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Conserved domains on  [gi|564368470|ref|XP_006245025|]
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NIF3-like protein 1 isoform X4 [Rattus norvegicus]

Protein Classification

Nif3-like dinuclear metal center hexameric protein( domain architecture ID 10484881)

Nif3-like dinuclear metal center hexameric protein may be a prohibitive factor restricting the infestation of certain pathogens

CATH:  3.40.1390.30
Gene Ontology:  GO:0046872

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NIF3 pfam01784
NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor ...
42-209 1.02e-48

NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.


:

Pssm-ID: 426431  Cd Length: 236  Bit Score: 163.56  E-value: 1.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470   42 LLSSLNDFASLSFAESWDNVGLLVEpSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKTWKERL 121
Cdd:pfam01784   2 IIELLEEIAPPELAEDWDNVGLQVG-DPENEVTKILVALDATEEVIEEAIENGADLIITHHPLIFRPLKSLTGDDPKGRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470  122 VIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSkapnYPTEGTHRLeFSANHSQDLDKVMSAVK---GV 198
Cdd:pfam01784  81 IKKLIKNNISLYSAHTNLDAAPGGVNDWLAELLGLESIEPLEPT----EEGEGLGRI-GELPEPMSLEELAAKVKeklGL 155
                         170
                  ....*....|.
gi 564368470  199 GGVSVTSFPAR 209
Cdd:pfam01784 156 EGVRVVGDLDK 166
 
Name Accession Description Interval E-value
NIF3 pfam01784
NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor ...
42-209 1.02e-48

NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.


Pssm-ID: 426431  Cd Length: 236  Bit Score: 163.56  E-value: 1.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470   42 LLSSLNDFASLSFAESWDNVGLLVEpSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKTWKERL 121
Cdd:pfam01784   2 IIELLEEIAPPELAEDWDNVGLQVG-DPENEVTKILVALDATEEVIEEAIENGADLIITHHPLIFRPLKSLTGDDPKGRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470  122 VIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSkapnYPTEGTHRLeFSANHSQDLDKVMSAVK---GV 198
Cdd:pfam01784  81 IKKLIKNNISLYSAHTNLDAAPGGVNDWLAELLGLESIEPLEPT----EEGEGLGRI-GELPEPMSLEELAAKVKeklGL 155
                         170
                  ....*....|.
gi 564368470  199 GGVSVTSFPAR 209
Cdd:pfam01784 156 EGVRVVGDLDK 166
NIF3 COG0327
Putative GTP cyclohydrolase 1 type 2, NIF3 family [Coenzyme transport and metabolism]; ...
37-170 1.81e-34

Putative GTP cyclohydrolase 1 type 2, NIF3 family [Coenzyme transport and metabolism]; Putative GTP cyclohydrolase 1 type 2, NIF3 family is part of the Pathway/BioSystem: Folate biosynthesis


Pssm-ID: 440096  Cd Length: 254  Bit Score: 126.80  E-value: 1.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470  37 MDLKALLSSLNDFASLSFAESWDNVGLLV-EPSPPhtVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWK 115
Cdd:COG0327    1 MTLSELVAALEELLPPALAESWDPNGLQVgEGRAE--VTRIVTAVDATQAVIEEAIEAGADLLIVHHPLFWKGEDSITAG 78
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564368470 116 TWKERLVIRALENRVAIYSPHTAYDAAPQ-GVNSWLAKGLGTCTTRPIHPSKAPNY 170
Cdd:COG0327   79 TVKGRRLALLIKNDIALYAAHTPLDAHPElGNNAQLARLLGLEDVEPLGPSGGEGL 134
YbgI_SA1388 TIGR00486
dinuclear metal center protein, YbgI/SA1388 family; The characterization of this family of ...
37-155 1.28e-25

dinuclear metal center protein, YbgI/SA1388 family; The characterization of this family of uncharacterized proteins as orthologous is tentative. Members are found in all three domains of life. Several members (from Bacillus subtilis, Listeria monocytogenes, and Mycobacterium tuberculosis - all classified as Firmicutes within the Eubacteria) share a long insert relative to other members. [Unknown function, General]


Pssm-ID: 213534  Cd Length: 249  Bit Score: 103.24  E-value: 1.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470   37 MDLKALLSSLNDFASLSFAESWDNVGLLVEpSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKT 116
Cdd:TIGR00486   1 MNLDELIQLINRFLPKELAEDGDNNGLQVG-SGNEEVKKVVVAVDASESVADEAVRLGADLIITHHPLIWKPLKRLIRGI 79
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 564368470  117 WKERLVIrALENRVAIYSPHTAYDAAPQGVNSWLAKGLG 155
Cdd:TIGR00486  80 KPGRLKI-LLQNDISLYSAHTNLDAHDGGNNDALARALG 117
 
Name Accession Description Interval E-value
NIF3 pfam01784
NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor ...
42-209 1.02e-48

NIF3 (NGG1p interacting factor 3); This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.


Pssm-ID: 426431  Cd Length: 236  Bit Score: 163.56  E-value: 1.02e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470   42 LLSSLNDFASLSFAESWDNVGLLVEpSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKTWKERL 121
Cdd:pfam01784   2 IIELLEEIAPPELAEDWDNVGLQVG-DPENEVTKILVALDATEEVIEEAIENGADLIITHHPLIFRPLKSLTGDDPKGRR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470  122 VIRALENRVAIYSPHTAYDAAPQGVNSWLAKGLGTCTTRPIHPSkapnYPTEGTHRLeFSANHSQDLDKVMSAVK---GV 198
Cdd:pfam01784  81 IKKLIKNNISLYSAHTNLDAAPGGVNDWLAELLGLESIEPLEPT----EEGEGLGRI-GELPEPMSLEELAAKVKeklGL 155
                         170
                  ....*....|.
gi 564368470  199 GGVSVTSFPAR 209
Cdd:pfam01784 156 EGVRVVGDLDK 166
NIF3 COG0327
Putative GTP cyclohydrolase 1 type 2, NIF3 family [Coenzyme transport and metabolism]; ...
37-170 1.81e-34

Putative GTP cyclohydrolase 1 type 2, NIF3 family [Coenzyme transport and metabolism]; Putative GTP cyclohydrolase 1 type 2, NIF3 family is part of the Pathway/BioSystem: Folate biosynthesis


Pssm-ID: 440096  Cd Length: 254  Bit Score: 126.80  E-value: 1.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470  37 MDLKALLSSLNDFASLSFAESWDNVGLLV-EPSPPhtVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWK 115
Cdd:COG0327    1 MTLSELVAALEELLPPALAESWDPNGLQVgEGRAE--VTRIVTAVDATQAVIEEAIEAGADLLIVHHPLFWKGEDSITAG 78
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 564368470 116 TWKERLVIRALENRVAIYSPHTAYDAAPQ-GVNSWLAKGLGTCTTRPIHPSKAPNY 170
Cdd:COG0327   79 TVKGRRLALLIKNDIALYAAHTPLDAHPElGNNAQLARLLGLEDVEPLGPSGGEGL 134
YbgI_SA1388 TIGR00486
dinuclear metal center protein, YbgI/SA1388 family; The characterization of this family of ...
37-155 1.28e-25

dinuclear metal center protein, YbgI/SA1388 family; The characterization of this family of uncharacterized proteins as orthologous is tentative. Members are found in all three domains of life. Several members (from Bacillus subtilis, Listeria monocytogenes, and Mycobacterium tuberculosis - all classified as Firmicutes within the Eubacteria) share a long insert relative to other members. [Unknown function, General]


Pssm-ID: 213534  Cd Length: 249  Bit Score: 103.24  E-value: 1.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368470   37 MDLKALLSSLNDFASLSFAESWDNVGLLVEpSPPHTVNTLFLTNDLTEEVMEEALQKKADLILSYHPPIFRPMKHITWKT 116
Cdd:TIGR00486   1 MNLDELIQLINRFLPKELAEDGDNNGLQVG-SGNEEVKKVVVAVDASESVADEAVRLGADLIITHHPLIWKPLKRLIRGI 79
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 564368470  117 WKERLVIrALENRVAIYSPHTAYDAAPQGVNSWLAKGLG 155
Cdd:TIGR00486  80 KPGRLKI-LLQNDISLYSAHTNLDAHDGGNNDALARALG 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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