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Conserved domains on  [gi|564368806|ref|XP_006245167|]
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ribulose-phosphate 3-epimerase isoform X2 [Rattus norvegicus]

Protein Classification

ribulose-phosphate 3-epimerase( domain architecture ID 10087218)

ribulose-phosphate 3-epimerase catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate

EC:  5.1.3.1
Gene Ontology:  GO:0046872|GO:0004750

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-238 2.94e-116

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


:

Pssm-ID: 238244  Cd Length: 211  Bit Score: 331.37  E-value: 2.94e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgqdpffvcpdamppsypTHFFFld 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKH------------------TDLPL-- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 lDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:cd00429   61 -DVHLMVENPERYIEAFAKAGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVM 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:cd00429  135 SVNPGFGGQKFIPEVLEKIRKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
 
Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-238 2.94e-116

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


Pssm-ID: 238244  Cd Length: 211  Bit Score: 331.37  E-value: 2.94e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgqdpffvcpdamppsypTHFFFld 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKH------------------TDLPL-- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 lDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:cd00429   61 -DVHLMVENPERYIEAFAKAGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVM 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:cd00429  135 SVNPGFGGQKFIPEVLEKIRKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
PTZ00170 PTZ00170
D-ribulose-5-phosphate 3-epimerase; Provisional
 7-240 1.20e-104

D-ribulose-5-phosphate 3-epimerase; Provisional


Pssm-ID: 240303  Cd Length: 228  Bit Score: 302.67  E-value: 1.20e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgQDPFFvcpdamppsypthfffldl 86
Cdd:PTZ00170   9 IAPSILAADFSKLADEAQDVLSGGADWLHVDVMDGHFVPNLSFGPPVVKSLRKHL-PNTFL------------------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  87 DMHMMVSRPEQWVKPMAVAGANQYTFHLEATEN-PGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAP--WANQIDMAL 163
Cdd:PTZ00170  69 DCHLMVSNPEKWVDDFAKAGASQFTFHIEATEDdPKAVARKIREAGMK-----VGVAIKPKTPVEVLFPliDTDLVDMVL 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564368806 164 VMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 240
Cdd:PTZ00170 144 VMTVEPGFGGQSFMHDMMPKVRELRKRYPHLNIQVDGGINLETIDIAADAGANVIVAGSSIFKAKDRKQAIELLRES 220
Rpe COG0036
Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; ...
 5-244 5.24e-101

Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Pentose-5-phosphate-3-epimerase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439806  Cd Length: 218  Bit Score: 292.75  E-value: 5.24e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   5 CKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqlgqdpffvcpdamppsYPTHFFfl 84
Cdd:COG0036    1 IKIAPSILSADFANLGEEVKRVEAAGADWIHIDVMDGHFVPNLTFGPPVVKALRK-----------------HTDLPL-- 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  85 dlDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALV 164
Cdd:COG0036   62 --DVHLMIENPDRYIEAFAEAGADIITVHAEATPHLHRTLQLIKELGAK-----AGVALNPATPLEALEYVLDDVDLVLV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806 165 MTVEPGFGGQKFMEDMMPKVHWLRTQF----PTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 240
Cdd:COG0036  135 MSVNPGFGGQKFIPSVLEKIRRLRELIdergLDILIEVDGGINAETIPELAEAGADVLVAGSAVFGAEDYAAAIAALREA 214


                 ....
gi 564368806 241 CSEA 244
Cdd:COG0036  215 AAAA 218
rpe TIGR01163
ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also ...
 7-238 3.16e-75

ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also known as pentose-5-phosphate 3-epimerase (PPE). PPE converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. It has been found in a wide range of bacteria, archebacteria, fungi and plants. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273475  Cd Length: 210  Bit Score: 227.16  E-value: 3.16e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806    7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqlgqdpffvcpdamppsYPThfffLDL 86
Cdd:TIGR01163   1 IAPSILSADFARLGEEVKAVEEAGADWIHVDVMDGHFVPNLTFGPPVLEALRK-----------------YTD----LPI 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   87 DMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMT 166
Cdd:TIGR01163  60 DVHLMVENPDRYIEDFAEAGADIITVHPEASEHIHRLLQLIKDLGAK-----AGIVLNPATPLEFLEYVLPDVDLVLLMS 134

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564368806  167 VEPGFGGQKFMEDMMPKVHWLRT----QFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:TIGR01163 135 VNPGFGGQKFIPDTLEKIREVRKmideLGLSILIEVDGGVNDDNARELAEAGADILVAGSAIFGADDYKEVIRSLR 210
Ribul_P_3_epim pfam00834
Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose ...
 6-224 3.74e-74

Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose 5-phosphate into D-xylulose 5-phosphate.


Pssm-ID: 395672  Cd Length: 198  Bit Score: 224.13  E-value: 3.74e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806    6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGqdpffvcpdamppsypthfffLD 85
Cdd:pfam00834   1 KIAPSILSADFARLGEEIKAVENAGADWLHVDVMDGHFVPNLTIGPLVVEALRPLTD---------------------LP 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   86 LDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:pfam00834  60 LDVHLMVEEPDRIIPDFAKAGADIISFHAEATPHPHRTIQLIKEAGAK-----AGLVLNPATPLDAIEYLLDKLDLVLLM 134

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564368806  166 TVEPGFGGQKFMEDMMPKVHWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAI 224
Cdd:pfam00834 135 SVNPGFGGQSFIPSVLEKIRKVRKMIDerglDTLIEVDGGIKLDNIPQIAEAGADVIVAGSAV 197
 
Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-238 2.94e-116

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


Pssm-ID: 238244  Cd Length: 211  Bit Score: 331.37  E-value: 2.94e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgqdpffvcpdamppsypTHFFFld 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKH------------------TDLPL-- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 lDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:cd00429   61 -DVHLMVENPERYIEAFAKAGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVM 134

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:cd00429  135 SVNPGFGGQKFIPEVLEKIRKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
PTZ00170 PTZ00170
D-ribulose-5-phosphate 3-epimerase; Provisional
 7-240 1.20e-104

D-ribulose-5-phosphate 3-epimerase; Provisional


Pssm-ID: 240303  Cd Length: 228  Bit Score: 302.67  E-value: 1.20e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgQDPFFvcpdamppsypthfffldl 86
Cdd:PTZ00170   9 IAPSILAADFSKLADEAQDVLSGGADWLHVDVMDGHFVPNLSFGPPVVKSLRKHL-PNTFL------------------- 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  87 DMHMMVSRPEQWVKPMAVAGANQYTFHLEATEN-PGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAP--WANQIDMAL 163
Cdd:PTZ00170  69 DCHLMVSNPEKWVDDFAKAGASQFTFHIEATEDdPKAVARKIREAGMK-----VGVAIKPKTPVEVLFPliDTDLVDMVL 143

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564368806 164 VMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 240
Cdd:PTZ00170 144 VMTVEPGFGGQSFMHDMMPKVRELRKRYPHLNIQVDGGINLETIDIAADAGANVIVAGSSIFKAKDRKQAIELLRES 220
Rpe COG0036
Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; ...
 5-244 5.24e-101

Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Pentose-5-phosphate-3-epimerase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439806  Cd Length: 218  Bit Score: 292.75  E-value: 5.24e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   5 CKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqlgqdpffvcpdamppsYPTHFFfl 84
Cdd:COG0036    1 IKIAPSILSADFANLGEEVKRVEAAGADWIHIDVMDGHFVPNLTFGPPVVKALRK-----------------HTDLPL-- 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  85 dlDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALV 164
Cdd:COG0036   62 --DVHLMIENPDRYIEAFAEAGADIITVHAEATPHLHRTLQLIKELGAK-----AGVALNPATPLEALEYVLDDVDLVLV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806 165 MTVEPGFGGQKFMEDMMPKVHWLRTQF----PTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 240
Cdd:COG0036  135 MSVNPGFGGQKFIPSVLEKIRRLRELIdergLDILIEVDGGINAETIPELAEAGADVLVAGSAVFGAEDYAAAIAALREA 214


                 ....
gi 564368806 241 CSEA 244
Cdd:COG0036  215 AAAA 218
PLN02334 PLN02334
ribulose-phosphate 3-epimerase
 1-247 9.27e-100

ribulose-phosphate 3-epimerase


Pssm-ID: 215192  Cd Length: 229  Bit Score: 290.36  E-value: 9.27e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   1 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgqdpffvcPDAMppsypth 80
Cdd:PLN02334   4 SKNDAIIAPSILSADFANLAEEAKRVLDAGADWLHVDVMDGHFVPNLTIGPPVVKALRKH---------TDAP------- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  81 fffldLDMHMMVSRPEQWVKPMAVAGANQYTFHLE--ATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPW--A 156
Cdd:PLN02334  68 -----LDCHLMVTNPEDYVPDFAKAGASIFTFHIEqaSTIHLHRLIQQIKSAGMK-----AGVVLNPGTPVEAVEPVveK 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806 157 NQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINL 236
Cdd:PLN02334 138 GLVDMVLVMSVEPGFGGQSFIPSMMDKVRALRKKYPELDIEVDGGVGPSTIDKAAEAGANVIVAGSAVFGAPDYAEVISG 217

                        250
                 ....*....|.
gi 564368806 237 LRNVCSEAAQK 247
Cdd:PLN02334 218 LRASVEKAAVA 228
PRK05581 PRK05581
ribulose-phosphate 3-epimerase; Validated
 6-239 5.94e-91

ribulose-phosphate 3-epimerase; Validated


Pssm-ID: 235515  Cd Length: 220  Bit Score: 267.43  E-value: 5.94e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqlgqdpffVCPdamppsypthfffLD 85
Cdd:PRK05581   5 LIAPSILSADFARLGEEVKAVEAAGADWIHVDVMDGHFVPNLTIGPPVVEAIRK--------VTK-------------LP 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 LDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:PRK05581  64 LDVHLMVENPDRYVPDFAKAGADIITFHVEASEHIHRLLQLIKSAGIK-----AGLVLNPATPLEPLEDVLDLLDLVLLM 138

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLR----TQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRN 239
Cdd:PRK05581 139 SVNPGFGGQKFIPEVLEKIRELRklidERGLDILIEVDGGINADNIKECAEAGADVFVAGSAVFGAPDYKEAIDSLRA 216
rpe TIGR01163
ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also ...
 7-238 3.16e-75

ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also known as pentose-5-phosphate 3-epimerase (PPE). PPE converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. It has been found in a wide range of bacteria, archebacteria, fungi and plants. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273475  Cd Length: 210  Bit Score: 227.16  E-value: 3.16e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806    7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqlgqdpffvcpdamppsYPThfffLDL 86
Cdd:TIGR01163   1 IAPSILSADFARLGEEVKAVEEAGADWIHVDVMDGHFVPNLTFGPPVLEALRK-----------------YTD----LPI 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   87 DMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMT 166
Cdd:TIGR01163  60 DVHLMVENPDRYIEDFAEAGADIITVHPEASEHIHRLLQLIKDLGAK-----AGIVLNPATPLEFLEYVLPDVDLVLLMS 134

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564368806  167 VEPGFGGQKFMEDMMPKVHWLRT----QFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:TIGR01163 135 VNPGFGGQKFIPDTLEKIREVRKmideLGLSILIEVDGGVNDDNARELAEAGADILVAGSAIFGADDYKEVIRSLR 210
Ribul_P_3_epim pfam00834
Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose ...
 6-224 3.74e-74

Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose 5-phosphate into D-xylulose 5-phosphate.


Pssm-ID: 395672  Cd Length: 198  Bit Score: 224.13  E-value: 3.74e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806    6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGqdpffvcpdamppsypthfffLD 85
Cdd:pfam00834   1 KIAPSILSADFARLGEEIKAVENAGADWLHVDVMDGHFVPNLTIGPLVVEALRPLTD---------------------LP 59

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   86 LDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:pfam00834  60 LDVHLMVEEPDRIIPDFAKAGADIISFHAEATPHPHRTIQLIKEAGAK-----AGLVLNPATPLDAIEYLLDKLDLVLLM 134

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564368806  166 TVEPGFGGQKFMEDMMPKVHWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAI 224
Cdd:pfam00834 135 SVNPGFGGQSFIPSVLEKIRKVRKMIDerglDTLIEVDGGIKLDNIPQIAEAGADVIVAGSAV 197
PRK09722 PRK09722
allulose-6-phosphate 3-epimerase; Provisional
 6-222 6.63e-43

allulose-6-phosphate 3-epimerase; Provisional


Pssm-ID: 236616  Cd Length: 229  Bit Score: 145.14  E-value: 6.63e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGaECLRMLDSGADYLHLDVMDGHFVPNITFghpvveslrkqlgqDPFFVCPDAMPPSYPthfffld 85
Cdd:PRK09722   4 KISPSLMCMDLLKFK-EQIEFLNSKADYFHIDIMDGHFVPNLTL--------------SPFFVSQVKKLASKP------- 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 LDMHMMVSRPEQWVKPMAVAGANQYTFHLEaTENPGA--LIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMAL 163
Cdd:PRK09722  62 LDVHLMVTDPQDYIDQLADAGADFITLHPE-TINGQAfrLIDEIRRAGMK-----VGLVLNPETPVESIKYYIHLLDKIT 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564368806 164 VMTVEPGFGGQKFMEDMMPKV----HWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGS 222
Cdd:PRK09722 136 VMTVDPGFAGQPFIPEMLDKIaelkALRERNGLEYLIEVDGSCNQKTYEKLMEAGADVFIVGT 198
PRK08005 PRK08005
ribulose-phosphate 3 epimerase family protein;
9-234 1.94e-31

ribulose-phosphate 3 epimerase family protein;


Pssm-ID: 169179  Cd Length: 210  Bit Score: 115.13  E-value: 1.94e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   9 PSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgqdpffvcpdampPSYPTHFffldldm 88
Cdd:PRK08005   5 PSLASADPLRYAEALTALHDAPLGSLHLDIEDTSFINNITFGMKTIQAVAQQ--------------TRHPLSF------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  89 HMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEylaPW---ANQIDMALVM 165
Cdd:PRK08005  64 HLMVSSPQRWLPWLAAIRPGWIFIHAESVQNPSEILADIRAIGAK-----AGLALNPATPLL---PYrylALQLDALMIM 135

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 234
Cdd:PRK08005 136 TSEPDGRGQQFIAAMCEKVSQSREHFPAAECWADGGITLRAARLLAAAGAQHLVIGRALFTTANYDVTL 204
PRK08091 PRK08091
ribulose-phosphate 3-epimerase; Validated
 6-229 3.37e-16

ribulose-phosphate 3-epimerase; Validated


Pssm-ID: 169215  Cd Length: 228  Bit Score: 74.91  E-value: 3.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESlrkqlgqdpffvcpdamppsYPTHFFfld 85
Cdd:PRK08091  14 PISVGILASNWLKFNETLTTLSENQLRLLHFDIADGQFSPFFTVGAIAIKQ--------------------FPTHCF--- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  86 LDMHMMVSRPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENgmKHCLLqVGLAIKPGTTVEYLAPWANQIDMALVM 165
Cdd:PRK08091  71 KDVHLMVRDQFEVAKACVAAGADIVTLQVEQTHDLALTIEWLAKQ--KTTVL-IGLCLCPETPISLLEPYLDQIDLIQIL 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564368806 166 TVEPGFGGQKFMEDMMPKVHWLRTQFPTLD----IEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDD 229
Cdd:PRK08091 148 TLDPRTGTKAPSDLILDRVIQVENRLGNRRveklISIDGSMTLELASYLKQHQIDWVVSGSALFSQGE 215
PRK14057 PRK14057
epimerase; Provisional
 34-228 7.04e-08

epimerase; Provisional


Pssm-ID: 172549  Cd Length: 254  Bit Score: 51.99  E-value: 7.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806  34 LHLDVMDGHFVPNITFGHPVVESLrkqlgqdpffvcpdamppsyPTHFFfldLDMHMMVSrpEQWVKPMAVAGANQYTFH 113
Cdd:PRK14057  49 LHLDLMDGQFCPQFTVGPWAVGQL--------------------PQTFI---KDVHLMVA--DQWTAAQACVKAGAHCIT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368806 114 LEAtENPGALIKDIRENGMK-------HCLLQVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHW 186
Cdd:PRK14057 104 LQA-EGDIHLHHTLSWLGQQtvpviggEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERVAQ 182

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 564368806 187 LRTQFPTLD----IEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSD 228
Cdd:PRK14057 183 LLCLLGDKRegkiIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDD 228
ThiE COG0352
Thiamine monophosphate synthase [Coenzyme transport and metabolism]; Thiamine monophosphate ...
 200-244 3.55e-06

Thiamine monophosphate synthase [Coenzyme transport and metabolism]; Thiamine monophosphate synthase is part of the Pathway/BioSystem: Thiamine biosynthesis


Pssm-ID: 440121 [Multi-domain]  Cd Length: 206  Bit Score: 46.33  E-value: 3.55e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 564368806 200 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEA 244
Cdd:COG0352  162 GGITPENAAEVLAAGADGVAVISAIWGAPDPAAAARELRAALEAA 206
TMP_TenI cd00564
Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step ...
 200-238 4.78e-06

Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.


Pssm-ID: 238317 [Multi-domain]  Cd Length: 196  Bit Score: 45.97  E-value: 4.78e-06
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 564368806 200 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 238
Cdd:cd00564  157 GGITPENAAEVLAAGADGVAVISAITGADDPAAAARELL 195
KGPDC_HPS cd04726
3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate ...
 196-234 2.08e-05

3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for L-ascorbate utilization in some eubacteria. HPS catalyzes the formation of D-arabino-3-hexulose-6-phosphate from D-ribulose 5-phosphate and formaldehyde in microorganisms that can use formaldehyde as a carbon source. Both catalyze reactions that involve the Mg2+-assisted formation and stabilization of 1,2-enediolate reaction intermediates.


Pssm-ID: 240077 [Multi-domain]  Cd Length: 202  Bit Score: 44.11  E-value: 2.08e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 564368806 196 IEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 234
Cdd:cd04726  161 VAVAGGITPDTLPEFKKAGADIVIVGRAITGAADPAEAA 199
thiE PRK00043
thiamine phosphate synthase;
200-245 1.35e-04

thiamine phosphate synthase;


Pssm-ID: 234590 [Multi-domain]  Cd Length: 212  Bit Score: 41.71  E-value: 1.35e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 564368806 200 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAA 245
Cdd:PRK00043 167 GGITPENAPEVLEAGADGVAVVSAITGAEDPEAAARALLAAFRAAR 212
PRK13307 PRK13307
bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase;
198-234 2.18e-04

bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase;


Pssm-ID: 183964 [Multi-domain]  Cd Length: 391  Bit Score: 41.92  E-value: 2.18e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 564368806 198 VDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 234
Cdd:PRK13307 335 VAGGVRVENVEEALKAGADILVVGRAITKSKDVRRAA 371
IGPS pfam00218
Indole-3-glycerol phosphate synthase;
204-234 2.04e-03

Indole-3-glycerol phosphate synthase;


Pssm-ID: 395163  Cd Length: 252  Bit Score: 38.43  E-value: 2.04e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 564368806  204 PDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 234
Cdd:pfam00218 220 PADVRELKEHGANAFLVGESLMRQEDVRAAI 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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