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Conserved domains on  [gi|564368810|ref|XP_006245169|]
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ribulose-phosphate 3-epimerase isoform X4 [Rattus norvegicus]

Protein Classification

ribulose-phosphate 3-epimerase( domain architecture ID 10087218)

ribulose-phosphate 3-epimerase catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate

EC:  5.1.3.1
Gene Ontology:  GO:0046872|GO:0004750

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-219 5.39e-120

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


:

Pssm-ID: 238244  Cd Length: 211  Bit Score: 339.84  E-value: 5.39e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgqDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKHT--DLPLDVHLMVENPERYIEAFAK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:cd00429   79 AGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVMSVNPGFGGQKFIPEVLEKI 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564368810 166 HWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:cd00429  154 RKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
 
Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-219 5.39e-120

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


Pssm-ID: 238244  Cd Length: 211  Bit Score: 339.84  E-value: 5.39e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgqDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKHT--DLPLDVHLMVENPERYIEAFAK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:cd00429   79 AGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVMSVNPGFGGQKFIPEVLEKI 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564368810 166 HWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:cd00429  154 RKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
PTZ00170 PTZ00170
D-ribulose-5-phosphate 3-epimerase; Provisional
 7-221 1.55e-109

D-ribulose-5-phosphate 3-epimerase; Provisional


Pssm-ID: 240303  Cd Length: 228  Bit Score: 314.23  E-value: 1.55e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgQDPFFDMHMMVSRPEQWVKPMAVA 86
Cdd:PTZ00170   9 IAPSILAADFSKLADEAQDVLSGGADWLHVDVMDGHFVPNLSFGPPVVKSLRKHL-PNTFLDCHLMVSNPEKWVDDFAKA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  87 GANQYTFHLEATEN-PGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAP--WANQIDMALVMTVEPGFGGQKFMEDMMP 163
Cdd:PTZ00170  88 GASQFTFHIEATEDdPKAVARKIREAGMK-----VGVAIKPKTPVEVLFPliDTDLVDMVLVMTVEPGFGGQSFMHDMMP 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564368810 164 KVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 221
Cdd:PTZ00170 163 KVRELRKRYPHLNIQVDGGINLETIDIAADAGANVIVAGSSIFKAKDRKQAIELLRES 220
Rpe COG0036
Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; ...
 5-225 6.82e-104

Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Pentose-5-phosphate-3-epimerase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439806  Cd Length: 218  Bit Score: 299.30  E-value: 6.82e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   5 CKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMA 84
Cdd:COG0036    1 IKIAPSILSADFANLGEEVKRVEAAGADWIHIDVMDGHFVPNLTFGPPVVKALRKH--TDLPLDVHLMIENPDRYIEAFA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  85 VAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPK 164
Cdd:COG0036   79 EAGADIITVHAEATPHLHRTLQLIKELGAK-----AGVALNPATPLEALEYVLDDVDLVLVMSVNPGFGGQKFIPSVLEK 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564368810 165 VHWLRTQF----PTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEA 225
Cdd:COG0036  154 IRRLRELIdergLDILIEVDGGINAETIPELAEAGADVLVAGSAVFGAEDYAAAIAALREAAAAA 218
Ribul_P_3_epim pfam00834
Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose ...
 6-205 6.15e-79

Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose 5-phosphate into D-xylulose 5-phosphate.


Pssm-ID: 395672  Cd Length: 198  Bit Score: 235.30  E-value: 6.15e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810    6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:pfam00834   1 KIAPSILSADFARLGEEIKAVENAGADWLHVDVMDGHFVPNLTIGPLVVEALRPL--TDLPLDVHLMVEEPDRIIPDFAK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:pfam00834  79 AGADIISFHAEATPHPHRTIQLIKEAGAK-----AGLVLNPATPLDAIEYLLDKLDLVLLMSVNPGFGGQSFIPSVLEKI 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 564368810  166 HWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAI 205
Cdd:pfam00834 154 RKVRKMIDerglDTLIEVDGGIKLDNIPQIAEAGADVIVAGSAV 197
rpe TIGR01163
ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also ...
 7-219 3.30e-78

ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also known as pentose-5-phosphate 3-epimerase (PPE). PPE converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. It has been found in a wide range of bacteria, archebacteria, fungi and plants. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273475  Cd Length: 210  Bit Score: 234.09  E-value: 3.30e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810    7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMAVA 86
Cdd:TIGR01163   1 IAPSILSADFARLGEEVKAVEEAGADWIHVDVMDGHFVPNLTFGPPVLEALRKY--TDLPIDVHLMVENPDRYIEDFAEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   87 GANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVH 166
Cdd:TIGR01163  79 GADIITVHPEASEHIHRLLQLIKDLGAK-----AGIVLNPATPLEFLEYVLPDVDLVLLMSVNPGFGGQKFIPDTLEKIR 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564368810  167 WLRT----QFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:TIGR01163 154 EVRKmideLGLSILIEVDGGVNDDNARELAEAGADILVAGSAIFGADDYKEVIRSLR 210
 
Name Accession Description Interval E-value
RPE cd00429
Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of ...
 6-219 5.39e-120

Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose phosphate pathway. In the Calvin cycle Ru5P is phosphorylated by phosphoribulose kinase to ribulose-1,5-bisphosphate, which in turn is used by RubisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) to incorporate CO2 as the central step in carbohydrate synthesis.


Pssm-ID: 238244  Cd Length: 211  Bit Score: 339.84  E-value: 5.39e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgqDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:cd00429    1 KIAPSILSADFANLGEELKRLEEAGADWIHIDVMDGHFVPNLTFGPPVVKALRKHT--DLPLDVHLMVENPERYIEAFAK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:cd00429   79 AGADIITFHAEATDHLHRTIQLIKELGMK-----AGVALNPGTPVEVLEPYLDEVDLVLVMSVNPGFGGQKFIPEVLEKI 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564368810 166 HWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:cd00429  154 RKLRELIPennlNLLIEVDGGINLETIPLLAEAGADVLVAGSALFGSDDYAEAIKELR 211
PTZ00170 PTZ00170
D-ribulose-5-phosphate 3-epimerase; Provisional
 7-221 1.55e-109

D-ribulose-5-phosphate 3-epimerase; Provisional


Pssm-ID: 240303  Cd Length: 228  Bit Score: 314.23  E-value: 1.55e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgQDPFFDMHMMVSRPEQWVKPMAVA 86
Cdd:PTZ00170   9 IAPSILAADFSKLADEAQDVLSGGADWLHVDVMDGHFVPNLSFGPPVVKSLRKHL-PNTFLDCHLMVSNPEKWVDDFAKA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  87 GANQYTFHLEATEN-PGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAP--WANQIDMALVMTVEPGFGGQKFMEDMMP 163
Cdd:PTZ00170  88 GASQFTFHIEATEDdPKAVARKIREAGMK-----VGVAIKPKTPVEVLFPliDTDLVDMVLVMTVEPGFGGQSFMHDMMP 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 564368810 164 KVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNV 221
Cdd:PTZ00170 163 KVRELRKRYPHLNIQVDGGINLETIDIAADAGANVIVAGSSIFKAKDRKQAIELLRES 220
Rpe COG0036
Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; ...
 5-225 6.82e-104

Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Pentose-5-phosphate-3-epimerase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 439806  Cd Length: 218  Bit Score: 299.30  E-value: 6.82e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   5 CKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMA 84
Cdd:COG0036    1 IKIAPSILSADFANLGEEVKRVEAAGADWIHIDVMDGHFVPNLTFGPPVVKALRKH--TDLPLDVHLMIENPDRYIEAFA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  85 VAGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPK 164
Cdd:COG0036   79 EAGADIITVHAEATPHLHRTLQLIKELGAK-----AGVALNPATPLEALEYVLDDVDLVLVMSVNPGFGGQKFIPSVLEK 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564368810 165 VHWLRTQF----PTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEA 225
Cdd:COG0036  154 IRRLRELIdergLDILIEVDGGINAETIPELAEAGADVLVAGSAVFGAEDYAAAIAALREAAAAA 218
PLN02334 PLN02334
ribulose-phosphate 3-epimerase
 1-228 1.92e-103

ribulose-phosphate 3-epimerase


Pssm-ID: 215192  Cd Length: 229  Bit Score: 298.84  E-value: 1.92e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   1 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLgqDPFFDMHMMVSRPEQWV 80
Cdd:PLN02334   4 SKNDAIIAPSILSADFANLAEEAKRVLDAGADWLHVDVMDGHFVPNLTIGPPVVKALRKHT--DAPLDCHLMVTNPEDYV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  81 KPMAVAGANQYTFHLE--ATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPW--ANQIDMALVMTVEPGFGGQK 156
Cdd:PLN02334  82 PDFAKAGASIFTFHIEqaSTIHLHRLIQQIKSAGMK-----AGVVLNPGTPVEAVEPVveKGLVDMVLVMSVEPGFGGQS 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564368810 157 FMEDMMPKVHWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAAQK 228
Cdd:PLN02334 157 FIPSMMDKVRALRKKYPELDIEVDGGVGPSTIDKAAEAGANVIVAGSAVFGAPDYAEVISGLRASVEKAAVA 228
PRK05581 PRK05581
ribulose-phosphate 3-epimerase; Validated
 6-220 1.24e-93

ribulose-phosphate 3-epimerase; Validated


Pssm-ID: 235515  Cd Length: 220  Bit Score: 273.60  E-value: 1.24e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqLGQDPfFDMHMMVSRPEQWVKPMAV 85
Cdd:PRK05581   5 LIAPSILSADFARLGEEVKAVEAAGADWIHVDVMDGHFVPNLTIGPPVVEAIRK-VTKLP-LDVHLMVENPDRYVPDFAK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:PRK05581  83 AGADIITFHVEASEHIHRLLQLIKSAGIK-----AGLVLNPATPLEPLEDVLDLLDLVLLMSVNPGFGGQKFIPEVLEKI 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564368810 166 HWLR----TQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRN 220
Cdd:PRK05581 158 RELRklidERGLDILIEVDGGINADNIKECAEAGADVFVAGSAVFGAPDYKEAIDSLRA 216
Ribul_P_3_epim pfam00834
Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose ...
 6-205 6.15e-79

Ribulose-phosphate 3 epimerase family; This enzyme catalyzes the conversion of D-ribulose 5-phosphate into D-xylulose 5-phosphate.


Pssm-ID: 395672  Cd Length: 198  Bit Score: 235.30  E-value: 6.15e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810    6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:pfam00834   1 KIAPSILSADFARLGEEIKAVENAGADWLHVDVMDGHFVPNLTIGPLVVEALRPL--TDLPLDVHLMVEEPDRIIPDFAK 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   86 AGANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:pfam00834  79 AGADIISFHAEATPHPHRTIQLIKEAGAK-----AGLVLNPATPLDAIEYLLDKLDLVLLMSVNPGFGGQSFIPSVLEKI 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 564368810  166 HWLRTQFP----TLDIEVDGGVGPDTVQKCAEAGANMIVSGSAI 205
Cdd:pfam00834 154 RKVRKMIDerglDTLIEVDGGIKLDNIPQIAEAGADVIVAGSAV 197
rpe TIGR01163
ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also ...
 7-219 3.30e-78

ribulose-phosphate 3-epimerase; This family consists of Ribulose-phosphate 3-epimerase, also known as pentose-5-phosphate 3-epimerase (PPE). PPE converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle. It has been found in a wide range of bacteria, archebacteria, fungi and plants. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273475  Cd Length: 210  Bit Score: 234.09  E-value: 3.30e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810    7 IGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQlgQDPFFDMHMMVSRPEQWVKPMAVA 86
Cdd:TIGR01163   1 IAPSILSADFARLGEEVKAVEEAGADWIHVDVMDGHFVPNLTFGPPVLEALRKY--TDLPIDVHLMVENPDRYIEDFAEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   87 GANQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVH 166
Cdd:TIGR01163  79 GADIITVHPEASEHIHRLLQLIKDLGAK-----AGIVLNPATPLEFLEYVLPDVDLVLLMSVNPGFGGQKFIPDTLEKIR 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564368810  167 WLRT----QFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:TIGR01163 154 EVRKmideLGLSILIEVDGGVNDDNARELAEAGADILVAGSAIFGADDYKEVIRSLR 210
PRK09722 PRK09722
allulose-6-phosphate 3-epimerase; Provisional
 6-203 2.73e-45

allulose-6-phosphate 3-epimerase; Provisional


Pssm-ID: 236616  Cd Length: 229  Bit Score: 150.92  E-value: 2.73e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGaECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKqLGQDPFfDMHMMVSRPEQWVKPMAV 85
Cdd:PRK09722   4 KISPSLMCMDLLKFK-EQIEFLNSKADYFHIDIMDGHFVPNLTLSPFFVSQVKK-LASKPL-DVHLMVTDPQDYIDQLAD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEaTENPGA--LIKDIRENGMKhcllqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMP 163
Cdd:PRK09722  81 AGADFITLHPE-TINGQAfrLIDEIRRAGMK-----VGLVLNPETPVESIKYYIHLLDKITVMTVDPGFAGQPFIPEMLD 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 564368810 164 KV----HWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGS 203
Cdd:PRK09722 155 KIaelkALRERNGLEYLIEVDGSCNQKTYEKLMEAGADVFIVGT 198
PRK08005 PRK08005
ribulose-phosphate 3 epimerase family protein;
9-215 6.71e-34

ribulose-phosphate 3 epimerase family protein;


Pssm-ID: 169179  Cd Length: 210  Bit Score: 120.91  E-value: 6.71e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   9 PSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFdmHMMVSRPEQWVKPMAVAGA 88
Cdd:PRK08005   5 PSLASADPLRYAEALTALHDAPLGSLHLDIEDTSFINNITFGMKTIQAVAQQTRHPLSF--HLMVSSPQRWLPWLAAIRP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  89 NQYTFHLEATENPGALIKDIRENGMKhcllqVGLAIKPGTTVEylaPW---ANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:PRK08005  83 GWIFIHAESVQNPSEILADIRAIGAK-----AGLALNPATPLL---PYrylALQLDALMIMTSEPDGRGQQFIAAMCEKV 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 564368810 166 HWLRTQFPTLDIEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 215
Cdd:PRK08005 155 SQSREHFPAAECWADGGITLRAARLLAAAGAQHLVIGRALFTTANYDVTL 204
PRK08091 PRK08091
ribulose-phosphate 3-epimerase; Validated
 6-210 3.33e-17

ribulose-phosphate 3-epimerase; Validated


Pssm-ID: 169215  Cd Length: 228  Bit Score: 77.22  E-value: 3.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810   6 KIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVeslrKQLGQDPFFDMHMMVSRPEQWVKPMAV 85
Cdd:PRK08091  14 PISVGILASNWLKFNETLTTLSENQLRLLHFDIADGQFSPFFTVGAIAI----KQFPTHCFKDVHLMVRDQFEVAKACVA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  86 AGANQYTFHLEATENPGALIKDIRENgmKHCLLqVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKV 165
Cdd:PRK08091  90 AGADIVTLQVEQTHDLALTIEWLAKQ--KTTVL-IGLCLCPETPISLLEPYLDQIDLIQILTLDPRTGTKAPSDLILDRV 166

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 564368810 166 HWLRTQFPTLD----IEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDD 210
Cdd:PRK08091 167 IQVENRLGNRRveklISIDGSMTLELASYLKQHQIDWVVSGSALFSQGE 215
PRK14057 PRK14057
epimerase; Provisional
 34-209 6.15e-11

epimerase; Provisional


Pssm-ID: 172549  Cd Length: 254  Bit Score: 60.47  E-value: 6.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810  34 LHLDVMDGHFVPNITFGHPVVeslrKQLGQDPFFDMHMMVSrpEQWVKPMAVAGANQYTFHLEAtENPGALIKDIRENGM 113
Cdd:PRK14057  49 LHLDLMDGQFCPQFTVGPWAV----GQLPQTFIKDVHLMVA--DQWTAAQACVKAGAHCITLQA-EGDIHLHHTLSWLGQ 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564368810 114 K-------HCLLQVGLAIKPGTTVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPTLD----IEVDGG 182
Cdd:PRK14057 122 QtvpviggEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERVAQLLCLLGDKRegkiIVIDGS 201

                        170       180
                 ....*....|....*....|....*..
gi 564368810 183 VGPDTVQKCAEAGANMIVSGSAIMRSD 209
Cdd:PRK14057 202 LTQDQLPSLIAQGIDRVVSGSALFRDD 228
ThiE COG0352
Thiamine monophosphate synthase [Coenzyme transport and metabolism]; Thiamine monophosphate ...
 181-225 3.74e-06

Thiamine monophosphate synthase [Coenzyme transport and metabolism]; Thiamine monophosphate synthase is part of the Pathway/BioSystem: Thiamine biosynthesis


Pssm-ID: 440121 [Multi-domain]  Cd Length: 206  Bit Score: 45.95  E-value: 3.74e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 564368810 181 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEA 225
Cdd:COG0352  162 GGITPENAAEVLAAGADGVAVISAIWGAPDPAAAARELRAALEAA 206
TMP_TenI cd00564
Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step ...
 181-219 4.03e-06

Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl) thiazole phosphate to yield thiamine phosphate. TenI is a enzymatically inactive regulatory protein involved in the regulation of several extracellular enzymes. This superfamily also contains other enzymatically inactive proteins with unknown functions.


Pssm-ID: 238317 [Multi-domain]  Cd Length: 196  Bit Score: 45.97  E-value: 4.03e-06
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 564368810 181 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLR 219
Cdd:cd00564  157 GGITPENAAEVLAAGADGVAVISAITGADDPAAAARELL 195
KGPDC_HPS cd04726
3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate ...
 177-215 2.70e-05

3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for L-ascorbate utilization in some eubacteria. HPS catalyzes the formation of D-arabino-3-hexulose-6-phosphate from D-ribulose 5-phosphate and formaldehyde in microorganisms that can use formaldehyde as a carbon source. Both catalyze reactions that involve the Mg2+-assisted formation and stabilization of 1,2-enediolate reaction intermediates.


Pssm-ID: 240077 [Multi-domain]  Cd Length: 202  Bit Score: 43.72  E-value: 2.70e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 564368810 177 IEVDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 215
Cdd:cd04726  161 VAVAGGITPDTLPEFKKAGADIVIVGRAITGAADPAEAA 199
thiE PRK00043
thiamine phosphate synthase;
181-226 1.48e-04

thiamine phosphate synthase;


Pssm-ID: 234590 [Multi-domain]  Cd Length: 212  Bit Score: 41.32  E-value: 1.48e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 564368810 181 GGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVINLLRNVCSEAA 226
Cdd:PRK00043 167 GGITPENAPEVLEAGADGVAVVSAITGAEDPEAAARALLAAFRAAR 212
PRK13307 PRK13307
bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase;
179-215 2.05e-04

bifunctional 5,6,7,8-tetrahydromethanopterin hydro-lyase/3-hexulose-6-phosphate synthase;


Pssm-ID: 183964 [Multi-domain]  Cd Length: 391  Bit Score: 41.54  E-value: 2.05e-04
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 564368810 179 VDGGVGPDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 215
Cdd:PRK13307 335 VAGGVRVENVEEALKAGADILVVGRAITKSKDVRRAA 371
IGPS pfam00218
Indole-3-glycerol phosphate synthase;
185-215 1.75e-03

Indole-3-glycerol phosphate synthase;


Pssm-ID: 395163  Cd Length: 252  Bit Score: 38.43  E-value: 1.75e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 564368810  185 PDTVQKCAEAGANMIVSGSAIMRSDDPRAVI 215
Cdd:pfam00218 220 PADVRELKEHGANAFLVGESLMRQEDVRAAI 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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