NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|568924495|ref|XP_006502355|]
View 

B-cell CLL/lymphoma 9 protein isoform X3 [Mus musculus]

Protein Classification

BCL9 and PHA03247 domain-containing protein( domain architecture ID 10568824)

BCL9 and PHA03247 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 496-1086 7.74e-15

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 80.37  E-value: 7.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  496 SEMEGPNVPNPASRPGLSGVSWPDDVPkiPDGRNFPpgqGVFSGPGRGERFPnPQGLSEEMFQQQLAEKQLALPPGMSME 575
Cdd:PHA03247 2484 AEARFPFAAGAAPDPGGGGPPDPDAPP--APSRLAP---AILPDEPVGEPVH-PRMLTWIRGLEELASDDAGDPPPPLPP 2557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  576 GIRPGMEmNRMIPGSQ---RHMEPG-----------SNPIFPRIPVEGPLSPSRGDFPKGMPPQIGPGRELEFGMVPGGm 641
Cdd:PHA03247 2558 AAPPAAP-DRSVPPPRpapRPSEPAvtsrarrpdapPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA- 2635

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  642 kgevNLNVNMGSSSQMIPQKMREAGAGPEEMMKLRpgssemlpAQQKMVPLPFGEHPQqeygvGPRPflpmsqgpgsnsg 721
Cdd:PHA03247 2636 ----NEPDPHPPPTVPPPERPRDDPAPGRVSRPRR--------ARRLGRAAQASSPPQ-----RPRR------------- 2685

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  722 lRNLREPIGPdqrtNSRLSHMPPLPLNPSSNPTSLSTAPPVqrglgrkPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 801
Cdd:PHA03247 2686 -RAARPTVGS----LTSLADPPPPPPTPEPAPHALVSATPL-------PPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  802 GSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTM 881
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTS 2833

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  882 ASPAmlGSVESGGPPPPTASQPASVnIPGSLPSSTPYPMPPePTLSQNPLSIMMSRMSKFAMPSSTplyhdaiKTVASSD 961
Cdd:PHA03247 2834 AQPT--APPPPPGPPPPSLPLGGSV-APGGDVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRST-------ESFALPP 2902

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  962 DDSPPARSPNLPsmnsmpgmgintQNPRISGPNPVVPMPTLSPmgMTQPLSHSNQMPSPNAMGPSIPPHGVPmgpglmsh 1041
Cdd:PHA03247 2903 DQPERPPQPQAP------------PPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVP-------- 2960

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 568924495 1042 NPIMGHGSqePPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPTGG 1086
Cdd:PHA03247 2961 QPWLGALV--PGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
BCL9 pfam11502
B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell ...
 276-312 1.45e-09

B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. BCL9 associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes.


:

Pssm-ID: 431912 [Multi-domain]  Cd Length: 37  Bit Score: 54.33  E-value: 1.45e-09
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 568924495   276 GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTAGQTG 312
Cdd:pfam11502    1 NLTPQQRQHRERQLATLRKMQRMLFPENQAGVGGDPS 37
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 496-1086 7.74e-15

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 80.37  E-value: 7.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  496 SEMEGPNVPNPASRPGLSGVSWPDDVPkiPDGRNFPpgqGVFSGPGRGERFPnPQGLSEEMFQQQLAEKQLALPPGMSME 575
Cdd:PHA03247 2484 AEARFPFAAGAAPDPGGGGPPDPDAPP--APSRLAP---AILPDEPVGEPVH-PRMLTWIRGLEELASDDAGDPPPPLPP 2557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  576 GIRPGMEmNRMIPGSQ---RHMEPG-----------SNPIFPRIPVEGPLSPSRGDFPKGMPPQIGPGRELEFGMVPGGm 641
Cdd:PHA03247 2558 AAPPAAP-DRSVPPPRpapRPSEPAvtsrarrpdapPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA- 2635

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  642 kgevNLNVNMGSSSQMIPQKMREAGAGPEEMMKLRpgssemlpAQQKMVPLPFGEHPQqeygvGPRPflpmsqgpgsnsg 721
Cdd:PHA03247 2636 ----NEPDPHPPPTVPPPERPRDDPAPGRVSRPRR--------ARRLGRAAQASSPPQ-----RPRR------------- 2685

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  722 lRNLREPIGPdqrtNSRLSHMPPLPLNPSSNPTSLSTAPPVqrglgrkPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 801
Cdd:PHA03247 2686 -RAARPTVGS----LTSLADPPPPPPTPEPAPHALVSATPL-------PPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  802 GSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTM 881
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTS 2833

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  882 ASPAmlGSVESGGPPPPTASQPASVnIPGSLPSSTPYPMPPePTLSQNPLSIMMSRMSKFAMPSSTplyhdaiKTVASSD 961
Cdd:PHA03247 2834 AQPT--APPPPPGPPPPSLPLGGSV-APGGDVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRST-------ESFALPP 2902

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  962 DDSPPARSPNLPsmnsmpgmgintQNPRISGPNPVVPMPTLSPmgMTQPLSHSNQMPSPNAMGPSIPPHGVPmgpglmsh 1041
Cdd:PHA03247 2903 DQPERPPQPQAP------------PPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVP-------- 2960

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 568924495 1042 NPIMGHGSqePPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPTGG 1086
Cdd:PHA03247 2961 QPWLGALV--PGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
BCL9 pfam11502
B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell ...
 276-312 1.45e-09

B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. BCL9 associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes.


Pssm-ID: 431912 [Multi-domain]  Cd Length: 37  Bit Score: 54.33  E-value: 1.45e-09
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 568924495   276 GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTAGQTG 312
Cdd:pfam11502    1 NLTPQQRQHRERQLATLRKMQRMLFPENQAGVGGDPS 37
ARS2 pfam04959
Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a ...
 1021-1107 5.64e-04

Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance.


Pssm-ID: 461498  Cd Length: 195  Bit Score: 42.56  E-value: 5.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  1021 NAMGPSIPPHGVPMGPglMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPTGGQGNFPGGIGFPGEG 1100
Cdd:pfam04959  111 DAKRPATPELKPKPPP--RPANRRERPGRAFPSQRPQGQMSDGHPRPPMDGPGGGPPFPPNQYGGGRGNYDNFRGQGGGG 188


                   ....*..
gi 568924495  1101 PLGRPSN 1107
Cdd:pfam04959  189 YPPKPRD 195
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 496-1086 7.74e-15

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 80.37  E-value: 7.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  496 SEMEGPNVPNPASRPGLSGVSWPDDVPkiPDGRNFPpgqGVFSGPGRGERFPnPQGLSEEMFQQQLAEKQLALPPGMSME 575
Cdd:PHA03247 2484 AEARFPFAAGAAPDPGGGGPPDPDAPP--APSRLAP---AILPDEPVGEPVH-PRMLTWIRGLEELASDDAGDPPPPLPP 2557

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  576 GIRPGMEmNRMIPGSQ---RHMEPG-----------SNPIFPRIPVEGPLSPSRGDFPKGMPPQIGPGRELEFGMVPGGm 641
Cdd:PHA03247 2558 AAPPAAP-DRSVPPPRpapRPSEPAvtsrarrpdapPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAA- 2635

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  642 kgevNLNVNMGSSSQMIPQKMREAGAGPEEMMKLRpgssemlpAQQKMVPLPFGEHPQqeygvGPRPflpmsqgpgsnsg 721
Cdd:PHA03247 2636 ----NEPDPHPPPTVPPPERPRDDPAPGRVSRPRR--------ARRLGRAAQASSPPQ-----RPRR------------- 2685

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  722 lRNLREPIGPdqrtNSRLSHMPPLPLNPSSNPTSLSTAPPVqrglgrkPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 801
Cdd:PHA03247 2686 -RAARPTVGS----LTSLADPPPPPPTPEPAPHALVSATPL-------PPGPAAARQASPALPAAPAPPAVPAGPATPGG 2753

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  802 GSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTM 881
Cdd:PHA03247 2754 PARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTS 2833

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  882 ASPAmlGSVESGGPPPPTASQPASVnIPGSLPSSTPYPMPPePTLSQNPLSIMMSRMSKFAMPSSTplyhdaiKTVASSD 961
Cdd:PHA03247 2834 AQPT--APPPPPGPPPPSLPLGGSV-APGGDVRRRPPSRSP-AAKPAAPARPPVRRLARPAVSRST-------ESFALPP 2902

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  962 DDSPPARSPNLPsmnsmpgmgintQNPRISGPNPVVPMPTLSPmgMTQPLSHSNQMPSPNAMGPSIPPHGVPmgpglmsh 1041
Cdd:PHA03247 2903 DQPERPPQPQAP------------PPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVP-------- 2960

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 568924495 1042 NPIMGHGSqePPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPTGG 1086
Cdd:PHA03247 2961 QPWLGALV--PGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
PHA03247 PHA03247
large tegument protein UL36; Provisional
 698-1127 7.56e-13

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 73.82  E-value: 7.56e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  698 PQQEYGVGPRPFLPMSQGPGSNSglrNLREPIGPDQRTNSRL----SHMPPLPLNPSSNPTSLSTAPPVQRGLGRKPLDI 773
Cdd:PHA03247 2562 AAPDRSVPPPRPAPRPSEPAVTS---RARRPDAPPQSARPRApvddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  774 SVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIksppvlgSAAASPVHLKSPSLPA 853
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL-------TSLADPPPPPPTPEPA 2711

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  854 PSPGWTSSPKPPLQSPGIPPNHKAPLTMASPamlgsvesggPPPPTASQPASVNIPGS--LPSSTPYPMPPeptlsqnpl 931
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPAPP----------AVPAGPATPGGPARPARppTTAGPPAPAPP--------- 2772

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  932 simmsrmskfAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNSMPGMGINTQNPRISGPNPVVPMPTLSPMgmTQPL 1011
Cdd:PHA03247 2773 ----------AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP--TAPP 2840

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495 1012 SHSNQMPSPNAMGPSIPPHG----------VPMGPGLMSHNPIMghgSQEPPMVPQGRMGFPQgfPPVQSPPQQVPFPHN 1081
Cdd:PHA03247 2841 PPPGPPPPSLPLGGSVAPGGdvrrrppsrsPAAKPAAPARPPVR---RLARPAVSRSTESFAL--PPDQPERPPQPQAPP 2915

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 568924495 1082 GPTGGQGNFPGGIGFPGEGPLGRPSNLPQSSADPALCKPGGPGAPD 1127
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ 2961
PHA03247 PHA03247
large tegument protein UL36; Provisional
 833-1280 1.63e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.12  E-value: 1.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  833 PPVLGSAAASPVHLKS--PSLPAPSPgwtssPKPPLQS----PGIPPNHKAPLTMASPamlgSVESGGPPPPTASQPASV 906
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSvpPPRPAPRP-----SEPAVTSrarrPDAPPQSARPRAPVDD----RGDPRGPAPPSPLPPDTH 2622

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  907 niPGSLPSSTPYPMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARsPNLPSMNSMPGMGINTQ 986
Cdd:PHA03247 2623 --APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR-PRRRAARPTVGSLTSLA 2699

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  987 NPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAMGPSIPPhGVPMGPGLmshnpimgHGSQEPPMVPQGRMGFPQGF 1066
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPP-AVPAGPAT--------PGGPARPARPPTTAGPPAPA 2770

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495 1067 PP---VQSPPQQVPFPHNGPTGGQGNFPGGIGFPGEGPLGRPsnlPQSSADPALCKPGGPGAPDSFTVlgnSMPSVFTDP 1143
Cdd:PHA03247 2771 PPaapAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVL---APAAALPPAASPAGPLPPPTSAQ---PTAPPPPPG 2844

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495 1144 DLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMSDQAPRMGLALPGMGGPGPVG 1223
Cdd:PHA03247 2845 PPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPP 2924

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568924495 1224 TPDIPLGTSPSMPGHNPMRPPAFLQQGMMGPHHRMMSP-----AQSTVPGPATLMTNPAAAV 1280
Cdd:PHA03247 2925 PPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPwlgalVPGRVAVPRFRVPQPAPSR 2986
BCL9 pfam11502
B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell ...
 276-312 1.45e-09

B-cell lymphoma 9 protein; The Wnt pathway plays a role in embryonic development, stem cell growth and tumorigenesis. BCL9 associates with beta-catenin and Tcf in the nucleus when the Wnt pathway is stimulated leading to the transactivation of Wnt target genes.


Pssm-ID: 431912 [Multi-domain]  Cd Length: 37  Bit Score: 54.33  E-value: 1.45e-09
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 568924495   276 GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTAGQTG 312
Cdd:pfam11502    1 NLTPQQRQHRERQLATLRKMQRMLFPENQAGVGGDPS 37
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
814-1050 1.09e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 1.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  814 PSQLAGMlAGPAAAASI----KSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAmlgS 889
Cdd:PRK12323  365 PGQSGGG-AGPATAAAApvaqPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQA---S 440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  890 VESGGPPPPTASQPASVNIPGSLPSSTPyPMPPEPTLSQNPLSIMMSRMSKfAMPSSTPLYHDAIKTVASsddDSPPARS 969
Cdd:PRK12323  441 ARGPGGAPAPAPAPAAAPAAAARPAAAG-PRPVAAAAAAAPARAAPAAAPA-PADDDPPPWEELPPEFAS---PAPAQPD 515

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  970 PNLPSMNSMPGMGINTQNPRISGPnPVVPMPTLSPMGMTQPLSHSNQMPSPNAMG-PSIPPHGVPMGPGLMSHNPIMGHG 1048
Cdd:PRK12323  516 AAPAGWVAESIPDPATADPDDAFE-TLAPAPAAAPAPRAAAATEPVVAPRPPRASaSGLPDMFDGDWPALAARLPVRGLA 594


                  ..
gi 568924495 1049 SQ 1050
Cdd:PRK12323  595 QQ 596
PHA03247 PHA03247
large tegument protein UL36; Provisional
 843-1298 3.49e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.31  E-value: 3.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  843 PVHLKSPSLPAPSPGWTSSPKPPLQSPGiPPNHKAPLTMAS--------PAM---------LGSVESGGPPPPTASQPAS 905
Cdd:PHA03247 2483 PAEARFPFAAGAAPDPGGGGPPDPDAPP-APSRLAPAILPDepvgepvhPRMltwirgleeLASDDAGDPPPPLPPAAPP 2561

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  906 VNIPGSLPSSTPYPMPPEPTLSqnplsimmsrmSKFAMPSSTPlyHDAIKTVASSDDDSPPARSPnlpsmnsmpgmgint 985
Cdd:PHA03247 2562 AAPDRSVPPPRPAPRPSEPAVT-----------SRARRPDAPP--QSARPRAPVDDRGDPRGPAP--------------- 2613

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  986 qnprisgPNPVVPMPTlspmgmtqplshsnqMPSPNAMGPSIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQG 1065
Cdd:PHA03247 2614 -------PSPLPPDTH---------------APDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLG 2671

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495 1066 FPPVQSPPQQVPFPHNGPTGgQGNFPGGIGFPGEGPLGRPSNLPQSSADPALCKPGGPGAPDSFTVLGNSMPSVFTDPDL 1145
Cdd:PHA03247 2672 RAAQASSPPQRPRRRAARPT-VGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPAT 2750

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495 1146 qevirPGAtgipefdlsriiPSEKPSQTLQYFPRGEVPGRKQPQGPGPgfshmqgmmsdQAPRMGLAlpgmggpgpvgtp 1225
Cdd:PHA03247 2751 -----PGG------------PARPARPPTTAGPPAPAPPAAPAAGPPR-----------RLTRPAVA------------- 2789

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568924495 1226 diplGTSPSMPGHNPMRPPAFLQQGMMGPhhrmmSPAQSTVPGPATLMTNPAAAVGMIPGKDRGPAGLYTHPG 1298
Cdd:PHA03247 2790 ----SLSESRESLPSPWDPADPPAAVLAP-----AAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
ARS2 pfam04959
Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a ...
 1021-1107 5.64e-04

Arsenite-resistance protein 2; Arsenite is a carcinogenic compound which can act as a co-mutagen by inhibiting DNA repair. Arsenite-resistance protein 2 is thought to play a role in arsenite resistance.


Pssm-ID: 461498  Cd Length: 195  Bit Score: 42.56  E-value: 5.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  1021 NAMGPSIPPHGVPMGPglMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPTGGQGNFPGGIGFPGEG 1100
Cdd:pfam04959  111 DAKRPATPELKPKPPP--RPANRRERPGRAFPSQRPQGQMSDGHPRPPMDGPGGGPPFPPNQYGGGRGNYDNFRGQGGGG 188


                   ....*..
gi 568924495  1101 PLGRPSN 1107
Cdd:pfam04959  189 YPPKPRD 195
KAR9 pfam08580
Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal ...
 771-1019 8.38e-04

Yeast cortical protein KAR9; The KAR9 protein in Saccharomyces cerevisiae is a cytoskeletal protein required for karyogamy, correct positioning of the mitotic spindle and for orientation of cytoplasmic microtubules. KAR9 localizes at the shmoo tip in mating cells and at the tip of the growing bud in anaphase.


Pssm-ID: 430088 [Multi-domain]  Cd Length: 684  Bit Score: 43.67  E-value: 8.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495   771 LDISVAGSQVHSPGINPLKSPTMHQVQSpmlGSPSGNLKSPqtPSQLAGMLAGPAAAASIKSPPVLGSAAA-SPVHLKSP 849
Cdd:pfam08580  418 EDSPATLVANKTPGSSPPSSVIMTPVNK---GSKTPSSRRG--SSFDFGSSSERVINSKLRRESKLPQIAStLKQTKRPS 492

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495   850 SLPAPSPgwtssPKPPLQSPgiPPNhkaPLTMASPAMLGSVESGGPPPPTASQPASVNIPGSLPSSTPYPMPPEPTLSQN 929
Cdd:pfam08580  493 KIPRASP-----NHSGFLST--PSN---TATSETPTPALRPPSRPQPPPPGNRPRWNASTNTNDLDVGHNFKPLTLTTPS 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495   930 PLSIMMSRmSKFAMPSSTPLYHDAiktvasSDDDSPPARSPnlpsmnSMPGMGINTQNP-RISGPNPvvPMPTLSPMGMT 1008
Cdd:pfam08580  563 PTPSRSSR-SSSTLPPVSPLSRDK------SRSPAPTCRSV------SRASRRRASRKPtRIGSPNS--RTSLLDEPPYP 627

                          250
                   ....*....|.
gi 568924495  1009 QpLSHSNQMPS 1019
Cdd:pfam08580  628 K-LTLSKGLPR 637
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 803-927 1.05e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 43.52  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  803 SPSGNLKSPQTPSQLAGMLAGpaAAASIKSPPVLGSAAASPVHLKSPSLPAP-SPGWTSSPKPPLQSPGIPPnhkAPltm 881
Cdd:PRK14959  372 RPSGGGASAPSGSAAEGPASG--GAATIPTPGTQGPQGTAPAAGMTPSSAAPaTPAPSAAPSPRVPWDDAPP---AP--- 443

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 568924495  882 aspamlgsVESGGPPPPTASQPASVNIPGSlPSSTPYPMPPEPTLS 927
Cdd:PRK14959  444 --------PRSGIPPRPAPRMPEASPVPGA-PDSVASASDAPPTLG 480
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 818-924 2.77e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.01  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  818 AGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGSVESGGPPP 897
Cdd:PRK14951  369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALA 448

                          90       100
                  ....*....|....*....|....*..
gi 568924495  898 PTASQPASVNIPGSLPSSTPYPMPPEP 924
Cdd:PRK14951  449 PAPPAQAAPETVAIPVRVAPEPAVASA 475
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 677-974 2.88e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 2.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  677 PGSSEMLPAQQKMVPLPFGEHPQQEyGVGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSL 756
Cdd:PHA03307   73 PGPGTEAPANESRSTPTWSLSTLAP-ASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAAS 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  757 STAPPVQRGlgrkpldiSVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTpsqlagmlAGPAAAASIKSPPVL 836
Cdd:PHA03307  152 PPAAGASPA--------AVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPA--------AASPRPPRRSSPISA 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  837 GSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPN-----HKAPLTMASPAMLGSV-ESGGPPPPTASQPASVNIPG 910
Cdd:PHA03307  216 SASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENecplpRPAPITLPTRIWEASGwNGPSSRPGPASSSSSPRERS 295

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568924495  911 SLPSSTPYPMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPS 974
Cdd:PHA03307  296 PSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPP 359
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
811-1005 3.98e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.40  E-value: 3.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  811 PQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGSV 890
Cdd:PRK12323  387 PAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAA 466

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  891 ESGGPPPPTASQPASVNIPGSLPSSTPYPMPPEPTLSQNPLSIMMSRMSkfamPSSTPLYHDAIKTVASSDDDSPPARSP 970
Cdd:PRK12323  467 AGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPD----AAPAGWVAESIPDPATADPDDAFETLA 542

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568924495  971 NLPSMNSMPGMGINTQnPRISGPNPVVPMPTLSPM 1005
Cdd:PRK12323  543 PAPAAAPAPRAAAATE-PVVAPRPPRASASGLPDM 576
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 811-924 5.07e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 5.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  811 PQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGSV 890
Cdd:PRK14951  371 EAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPA 450

                          90       100       110
                  ....*....|....*....|....*....|....
gi 568924495  891 ESGGPPPPTASQPASVNIPGSLPSSTPYPMPPEP 924
Cdd:PRK14951  451 PPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPA 484
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 818-949 5.38e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 5.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  818 AGMLAGPAAAASIKSPPVLGSAAASPVhlkspslPAPSPGWTSSPKPPLQSPGIPpnhkAPLTMASPAMLGSVESGGPPP 897
Cdd:PRK14951  368 AAAEAAAPAEKKTPARPEAAAPAAAPV-------AQAAAAPAPAAAPAAAASAPA----APPAAAPPAPVAAPAAAAPAA 436

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568924495  898 PTASQPASVNIPGSLPSSTPYPMPPEPTLSQNPLSIMMSRMSKFAMPSSTPL 949
Cdd:PRK14951  437 APAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARL 488
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 847-1027 5.73e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495   847 KSPSLPAPSPGW-TSSPKPPLQSPGIPPNHKAPLTMASPAmlgsveSGGPPPPTA--SQPASVNIPGSLPSSTPYPMPPE 923
Cdd:pfam05109  423 KAPESTTTSPTLnTTGFAAPNTTTGLPSSTHVPTNLTAPA------STGPTVSTAdvTSPTPAGTTSGASPVTPSPSPRD 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495   924 PTlSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNSMPGMGINTQNPRISGPNPVVPMPTLs 1003
Cdd:pfam05109  497 NG-TESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTL- 574

                          170       180
                   ....*....|....*....|....
gi 568924495  1004 pmGMTQPLShSNQMPSPNAMGPSI 1027
Cdd:pfam05109  575 --GKTSPTS-AVTTPTPNATSPTV 595
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
802-974 9.47e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  802 GSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGwTSSPKPPLQSPGIPPNHKAPLTM 881
Cdd:PRK07003  365 GGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAA-TRAEAPPAAPAPPATADRGDDAA 443

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568924495  882 ASPAMLGS-----VESGGPPPPTASQPASVNIPGSLP-SSTPYPMPPEPTLSQNPlsimmsrmskfAMPSSTPLYHDAIK 955
Cdd:PRK07003  444 DGDAPVPAkanarASADSRCDERDAQPPADSGSASAPaSDAPPDAAFEPAPRAAA-----------PSAATPAAVPDARA 512

                         170
                  ....*....|....*....
gi 568924495  956 TVASSDDDSPPARSPNLPS 974
Cdd:PRK07003  513 PAAASREDAPAAAAPPAPE 531
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH