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Conserved domains on  [gi|568953496|ref|XP_006508945|]
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cell division cycle protein 16 homolog isoform X1 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 13537404)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-418 8.89e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.05  E-value: 8.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 235 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 314
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 315 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 394
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180
                 ....*....|....*....|....
gi 568953496 395 HSLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAA 177
PEP_TPR_lipo super family cl37187
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 40-408 1.19e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


The actual alignment was detected with superfamily member TIGR02917:

Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496   40 LLRGKIYDALDNRTLATYSYKEALKLD-----VYCFEAFDLLTSHHMLTAQEEKE-LLDSLPLNKLCAEEQELLRFvfen 113
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALRpnniaVLLALATILIEAGEFEEAEKHADaLLKKAPNSPLAHYLKALVDF---- 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  114 KLKKYNKPSETVIpESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYL 193
Cdd:TIGR02917 273 QKKNYEDARETLQ-DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  194 SHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL---- 269
Cdd:TIGR02917 352 LSPALGLDPDDPAALSLLGEAYLALG-DFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdpel 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  270 ------------------------------MKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAF 319
Cdd:TIGR02917 431 gradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  320 QNGEWKTAEKWFLDAL----EKIKAI----------GNEVTVDKW------------EPLLnNLGHVCRKLKKYAEALDY 373
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLtidpKNLRAIlalaglylrtGNEEEAVAWlekaaelnpqeiEPAL-ALAQYYLGKGQLKKALAI 589

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 568953496  374 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYF 408
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-418 8.89e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.05  E-value: 8.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 235 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 314
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 315 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 394
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180
                 ....*....|....*....|....
gi 568953496 395 HSLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAA 177
TPR_12 pfam13424
Tetratricopeptide repeat;
353-417 4.88e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.88e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568953496  353 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 417
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 135-414 5.43e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 5.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  135 ENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCY 214
Cdd:TIGR02917 531 KNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRA 610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  215 YLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAY---------FTAAQLMKGCHL---------- 275
Cdd:TIGR02917 611 QLAAGDLNK-AVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLkralelkpdNTEAQIGLAQLLlaakrtesak 689

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  276 ----------PMLYIGLE-----YGLTNNSKLAERFFGQALSIAPEDPFVI--HEVGVVAFQNGE-WKTAEKW------- 330
Cdd:TIGR02917 690 kiakslqkqhPKAALGFElegdlYLRQKDYPAAIQAYRKALKRAPSSQNAIklHRALLASGNTAEaVKTLEAWlkthpnd 769

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  331 ----------FLDALEKIKAIGNEVTVDKWEP----LLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHS 396
Cdd:TIGR02917 770 avlrtalaelYLAQKDYDKAIKHYQTVVKKAPdnavVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLV 848

                         330
                  ....*....|....*...
gi 568953496  397 LMGNFENAVDYFHTALGL 414
Cdd:TIGR02917 849 EKGEADRALPLLRKAVNI 866
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 40-408 1.19e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496   40 LLRGKIYDALDNRTLATYSYKEALKLD-----VYCFEAFDLLTSHHMLTAQEEKE-LLDSLPLNKLCAEEQELLRFvfen 113
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALRpnniaVLLALATILIEAGEFEEAEKHADaLLKKAPNSPLAHYLKALVDF---- 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  114 KLKKYNKPSETVIpESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYL 193
Cdd:TIGR02917 273 QKKNYEDARETLQ-DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  194 SHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL---- 269
Cdd:TIGR02917 352 LSPALGLDPDDPAALSLLGEAYLALG-DFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdpel 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  270 ------------------------------MKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAF 319
Cdd:TIGR02917 431 gradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  320 QNGEWKTAEKWFLDAL----EKIKAI----------GNEVTVDKW------------EPLLnNLGHVCRKLKKYAEALDY 373
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLtidpKNLRAIlalaglylrtGNEEEAVAWlekaaelnpqeiEPAL-ALAQYYLGKGQLKKALAI 589

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 568953496  374 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYF 408
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 354-384 2.23e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.28  E-value: 2.23e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 568953496   354 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 384
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 134-269 7.60e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 7.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 134 QENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDP--FHANCLPVHIgtLVELNKANELFYLSHKLVDLYPSNPVSWFAV 211
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPdnPEAFALLGEI--LLQLGDLDEAIVLLHEALELDPDEPEARLNL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568953496 212 GCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL 269
Cdd:COG4783   79 GLALLKAGDYDE-ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 367-421 6.02e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.76  E-value: 6.02e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568953496 367 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 421
Cdd:cd24142   16 FELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 367-414 6.26e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 6.26e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568953496 367 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 414
Cdd:PRK02603  51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-418 8.89e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.05  E-value: 8.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 235 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 314
Cdd:COG0457    3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 315 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 394
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                        170       180
                 ....*....|....*....|....
gi 568953496 395 HSLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG0457  154 LEKLGRYEEALELLEKLEAAALAA 177
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
279-428 9.24e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.05  E-value: 9.24e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 279 YIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkIKAignevtvdKWEPLLNNLG 358
Cdd:COG0457   13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE-LDP--------DDAEALNNLG 83

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 359 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 428
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 272-418 1.47e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 73.69  E-value: 1.47e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 272 GCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWE 351
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE----------LDPDE 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568953496 352 P-LLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG4783   72 PeARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 207-428 3.35e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.92  E-value: 3.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 207 SWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGL 286
Cdd:COG2956   10 GWYFKGLNYLLNG-QPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLK 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 287 TNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAekwfLDALEKIKAIGnevtvDKWEPLLNNLGHVCRKLKK 366
Cdd:COG2956   89 AGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKA----IEVLERLLKLG-----PENAHAYCELAELYLEQGD 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568953496 367 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 428
Cdd:COG2956  160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 183-438 4.11e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.54  E-value: 4.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 183 ELNKANELFylsHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAA 262
Cdd:COG2956   23 QPDKAIDLL---EEALELDPETVEAHLALGNLYRRRGEYDR-AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEEL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 263 YFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKaig 342
Cdd:COG2956   99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDP--- 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 343 nevtvdKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFsV 422
Cdd:COG2956  176 ------DCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-L 248

                        250
                 ....*....|....*.
gi 568953496 423 TMLGHCIEMYIGDSEA 438
Cdd:COG2956  249 LALADLLERKEGLEAA 264
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
301-428 7.48e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.27  E-value: 7.48e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 301 LSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQALV 379
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE----------LDPDDAeALYNLGLAYLRLGRYEEALADYEQALE 70

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 568953496 380 LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 428
Cdd:COG0457   71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLA 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 208-439 2.68e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.80  E-value: 2.68e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 208 WFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQlmkgCHLPMLYIGLEygLT 287
Cdd:COG3914   18 LAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLA----ALLELAALLLQ--AL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 288 NNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKY 367
Cdd:COG3914   92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL---------NPDFAEAYLNLGEALRRLGRL 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568953496 368 AEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIeMYIGDSEAY 439
Cdd:COG3914  163 EEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL-RQACDWEVY 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 243-438 3.78e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.76  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 243 WIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNG 322
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 323 EWKTAEKWFLDALEkikaignevTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFE 402
Cdd:COG2956   91 LLDRAEELLEKLLE---------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD 161

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 568953496 403 NAVDYFHTALGLRRDDTFSVTMLGHcIEMYIGDSEA 438
Cdd:COG2956  162 EAIEALEKALKLDPDCARALLLLAE-LYLEQGDYEE 196
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 196-412 5.85e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 5.85e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 196 KLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHL 275
Cdd:COG2956   67 KLLERDPDRAEALLELAQDYLKAGLLDR-AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 276 PMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLN 355
Cdd:COG2956  146 AYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ---------DPDYLPALP 216

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568953496 356 NLGHVCRKLKKYAEALDYHRQALVLIPQNASTYsAIGYIHSLMGNFENAVDYFHTAL 412
Cdd:COG2956  217 RLAELYEKLGDPEEALELLRKALELDPSDDLLL-ALADLLERKEGLEAALALLERQL 272
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
317-417 4.15e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.72  E-value: 4.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 317 VAFQNGEWKTAEKWFLDALEKIKAIGNevtvdkwepLLNNLGHVCRKLKKYAEALDYhRQALVLIPQNASTYSAIGYIHS 396
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNAD---------ALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLL 70

                         90       100
                 ....*....|....*....|.
gi 568953496 397 LMGNFENAVDYFHTALGLRRD 417
Cdd:COG3063   71 ELGDYDEALAYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 275-426 5.01e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.51  E-value: 5.01e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 275 LPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLL 354
Cdd:COG2956    9 LGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER---------DPDRAEAL 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568953496 355 NNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 426
Cdd:COG2956   80 LELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
196-385 1.66e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.48  E-value: 1.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 196 KLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHL 275
Cdd:COG0457   33 KALELDPDDAEALYNLGLAYLRLGRYEE-ALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 276 PMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN 355
Cdd:COG0457  112 ALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALA 191

                        170       180       190
                 ....*....|....*....|....*....|
gi 568953496 356 NLGHVCRKLKKYAEALDYHRQALVLIPQNA 385
Cdd:COG0457  192 AAEVLLALLLALEQALRKKLAILTLAALAE 221
TPR_12 pfam13424
Tetratricopeptide repeat;
353-417 4.88e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.16  E-value: 4.88e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568953496  353 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 417
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 284-382 5.79e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 5.79e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 284 YGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAignevtvdkWEPLLNNLGHVCRK 363
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---------NPNAYSNLAALLLS 134

                         90
                 ....*....|....*....
gi 568953496 364 LKKYAEALDYHRQALVLIP 382
Cdd:COG5010  135 LGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 315-428 6.87e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 6.87e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 315 GVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 394
Cdd:COG4783   11 AQALLLAGDYDEAEALLEKALEL---------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110
                 ....*....|....*....|....*....|....
gi 568953496 395 HSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 428
Cdd:COG4783   82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 316-414 1.23e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.20  E-value: 1.23e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 316 VVAFQNGEWKTAEKWFLDALEKikaignevtvDKWEP-LLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 394
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQL----------DPNNPeLYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131

                         90       100
                 ....*....|....*....|
gi 568953496 395 HSLMGNFENAVDYFHTALGL 414
Cdd:COG5010  132 LLSLGQDDEAKAALQRALGT 151
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 181-346 1.24e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 181 LVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAM 260
Cdd:COG3914   88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE-ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAI 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 261 AAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKwFLDALEKIKA 340
Cdd:COG3914  167 AALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDR-FEELLAALAR 245


                 ....*.
gi 568953496 341 IGNEVT 346
Cdd:COG3914  246 GPSELS 251
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 208-337 2.00e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 2.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 208 WFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLT 287
Cdd:COG4783    7 LYALAQALLLAGDYDE-AEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 568953496 288 NNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEK 337
Cdd:COG4783   86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 360-426 3.22e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.04  E-value: 3.22e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568953496 360 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 426
Cdd:COG5010   63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLA 129
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 214-336 3.91e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.96  E-value: 3.91e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 214 YYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLA 293
Cdd:COG5010   28 EAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEA 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 568953496 294 ERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALE 336
Cdd:COG5010  108 KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 299-418 4.43e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 4.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 299 QALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQA 377
Cdd:COG4235    8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALR----------LDPDNAdALLDLAEALLAAGDTEEAEELLERA 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 568953496 378 LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG4235   78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 242-336 5.17e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 5.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 242 AWIAYGHSFAVESEHDQAMAAYFTAAQLMKGchLPMLYIGL--EYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAF 319
Cdd:COG4235   19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPD--NADALLDLaeALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                         90
                 ....*....|....*..
gi 568953496 320 QNGEWKTAEKWFLDALE 336
Cdd:COG4235   97 QQGDYAEAIAAWQKLLA 113
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 135-414 5.43e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 5.43e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  135 ENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCY 214
Cdd:TIGR02917 531 KNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRA 610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  215 YLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAY---------FTAAQLMKGCHL---------- 275
Cdd:TIGR02917 611 QLAAGDLNK-AVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLkralelkpdNTEAQIGLAQLLlaakrtesak 689

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  276 ----------PMLYIGLE-----YGLTNNSKLAERFFGQALSIAPEDPFVI--HEVGVVAFQNGE-WKTAEKW------- 330
Cdd:TIGR02917 690 kiakslqkqhPKAALGFElegdlYLRQKDYPAAIQAYRKALKRAPSSQNAIklHRALLASGNTAEaVKTLEAWlkthpnd 769

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  331 ----------FLDALEKIKAIGNEVTVDKWEP----LLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHS 396
Cdd:TIGR02917 770 avlrtalaelYLAQKDYDKAIKHYQTVVKKAPdnavVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLV 848

                         330
                  ....*....|....*...
gi 568953496  397 LMGNFENAVDYFHTALGL 414
Cdd:TIGR02917 849 EKGEADRALPLLRKAVNI 866
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 40-408 1.19e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 51.24  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496   40 LLRGKIYDALDNRTLATYSYKEALKLD-----VYCFEAFDLLTSHHMLTAQEEKE-LLDSLPLNKLCAEEQELLRFvfen 113
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALRpnniaVLLALATILIEAGEFEEAEKHADaLLKKAPNSPLAHYLKALVDF---- 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  114 KLKKYNKPSETVIpESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDPFHANCLPVHIGTLVELNKANELFYL 193
Cdd:TIGR02917 273 QKKNYEDARETLQ-DALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAT 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  194 SHKLVDLYPSNPVSWFAVGCYYLMVGhKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL---- 269
Cdd:TIGR02917 352 LSPALGLDPDDPAALSLLGEAYLALG-DFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLdpel 430

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  270 ------------------------------MKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAF 319
Cdd:TIGR02917 431 gradlllilsylrsgqfdkalaaakklekkQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI 510

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  320 QNGEWKTAEKWFLDAL----EKIKAI----------GNEVTVDKW------------EPLLnNLGHVCRKLKKYAEALDY 373
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLtidpKNLRAIlalaglylrtGNEEEAVAWlekaaelnpqeiEPAL-ALAQYYLGKGQLKKALAI 589

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 568953496  374 HRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYF 408
Cdd:TIGR02917 590 LNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSF 624
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 281-426 2.58e-06

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 48.87  E-value: 2.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  281 GLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALekikAIGNEVTvdkwePLLNNLG-H 359
Cdd:TIGR02521  38 ALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRAL----TLNPNNG-----DVLNNYGtF 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568953496  360 VCRKlKKYAEALDYHRQALV--LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDdtFSVTMLG 426
Cdd:TIGR02521 109 LCQQ-GKYEQAMQQFEQAIEdpLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQ--RPESLLE 174
TPR_12 pfam13424
Tetratricopeptide repeat;
312-378 3.40e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 3.40e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568953496  312 HEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEpLLNNLGHVCRKLKKYAEALDYHRQAL 378
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTAT-TLLNLGRLYLELGRYEEALELLERAL 72
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 202-308 4.19e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 202 PSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIG 281
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDE-ALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92

                         90       100
                 ....*....|....*....|....*..
gi 568953496 282 LEYGLTNNSKLAERFFGQALSIAPEDP 308
Cdd:COG4235   93 LAAFQQGDYAEAIAAWQKLLALLPADA 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 278-385 4.44e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.44e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 278 LYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNN 356
Cdd:COG4235   21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA----------LDPDNPeALYL 90

                         90       100
                 ....*....|....*....|....*....
gi 568953496 357 LGHVCRKLKKYAEALDYHRQALVLIPQNA 385
Cdd:COG4235   91 LGLAAFQQGDYAEAIAAWQKLLALLPADA 119
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
353-421 5.26e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.60  E-value: 5.26e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 353 LLNNLGHVCRKLKKYAEAL-DYhRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 421
Cdd:COG4785   75 LYYERGVAYDSLGDYDLAIaDF-DQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 354-426 6.02e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.95  E-value: 6.02e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568953496 354 LNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 426
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG 79
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
255-412 1.07e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 1.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 255 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDA 334
Cdd:COG4785   88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568953496 335 LEKikaignevtvDKWEPLLNNLGHVCRKLKKYAEALDYHRQAlvlipqnastysaIGYIHSLMGNFENAVDYFHTAL 412
Cdd:COG4785  168 LEL----------DPNDPERALWLYLAERKLDPEKALALLLED-------------WATAYLLQGDTEEARELFKLAL 222
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 356-426 2.02e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 44.23  E-value: 2.02e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568953496 356 NLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 426
Cdd:COG4235   22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 354-384 2.23e-05

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 41.28  E-value: 2.23e-05
                           10        20        30
                   ....*....|....*....|....*....|.
gi 568953496   354 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 384
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 215-305 2.41e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.57  E-value: 2.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 215 YLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAE 294
Cdd:COG5010   64 YNKLGDFEE-SLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAK 142

                         90
                 ....*....|.
gi 568953496 295 RFFGQALSIAP 305
Cdd:COG5010  143 AALQRALGTSP 153
TPR_1 pfam00515
Tetratricopeptide repeat;
354-384 3.20e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.87  E-value: 3.20e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568953496  354 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 384
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
COG3899 COG3899
Predicted ATPase [General function prediction only];
224-417 3.21e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 46.78  E-value: 3.21e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  224 HAR--RYLSKATTLEKTYGPAWIAYgHsFAVESEHDQAMAAYFTAAQLMKGCHLPmlyigleygltnnsKLAERFFGQAL 301
Cdd:COG3899   669 HRRiaRALEARGPEPLEERLFELAH-H-LNRAGERDRAARLLLRAARRALARGAY--------------AEALRYLERAL 732

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  302 SIAPEDPFVIHEV------GVVAFQNGEWKTAEKWFLDALEK--IKAIGNEVTVDKWEPL--LNNLGHVCRklKKYAEAL 371
Cdd:COG3899   733 ELLPPDPEEEYRLalllelAEALYLAGRFEEAEALLERALAAraLAALAALRHGNPPASAraYANLGLLLL--GDYEEAY 810

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 568953496  372 DYHRQALVLI------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 417
Cdd:COG3899   811 EFGELALALAerlgdrRLEARALFNLGFILHWLGPLREALELLREALEAGLE 862
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
360-427 3.98e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.46  E-value: 3.98e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568953496 360 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDyFHTALGLRRDDTFSVTMLGH 427
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAE 67
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
245-418 1.19e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 1.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 245 AYGHSFAVESEHDQAMAAYFTAAQLMKGC-HLPMLYIGLE---YGLTNNSKLAERFFGQALSI-----APEDPFVIHEVG 315
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALlFAAVLALAIAladLALALAAAALAAAALAAERIdralaLPDLAQLYYERG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 316 VVAFQNGEWKTAEKWFLDALEkIKAignevtvDKWEpLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIH 395
Cdd:COG4785   81 VAYDSLGDYDLAIADFDQALE-LDP-------DLAE-AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151

                        170       180
                 ....*....|....*....|...
gi 568953496 396 SLMGNFENAVDYFHTALGLRRDD 418
Cdd:COG4785  152 YYLGRYELAIADLEKALELDPND 174
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 279-412 1.41e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  279 YIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkiKAIGNevtVDKWepllNNLG 358
Cdd:TIGR02917 130 LRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLT--ADPGN---VDAL----LLKG 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568953496  359 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTAL 412
Cdd:TIGR02917 201 DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALL 254
TPR_11 pfam13414
TPR repeat;
358-399 5.24e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 5.24e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 568953496  358 GHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMG 399
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 274-414 7.54e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 7.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496  274 HLPMLYIG--LEYGLtNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEwktaekwFLDALEKIKAIGNEVTVDKwe 351
Cdd:TIGR02917 294 YLPALLLAgaSEYQL-GNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGR-------VDEAIATLSPALGLDPDDP-- 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568953496  352 PLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 414
Cdd:TIGR02917 364 AALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQL 426
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 134-269 7.60e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 7.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 134 QENLDVVVSLAERHYYNCDFKMCYKLTSTVMEKDP--FHANCLPVHIgtLVELNKANELFYLSHKLVDLYPSNPVSWFAV 211
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPdnPEAFALLGEI--LLQLGDLDEAIVLLHEALELDPDEPEARLNL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568953496 212 GCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQL 269
Cdd:COG4783   79 GLALLKAGDYDE-ALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
TPR_7 pfam13176
Tetratricopeptide repeat;
353-380 1.36e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 36.36  E-value: 1.36e-03
                          10        20
                  ....*....|....*....|....*...
gi 568953496  353 LLNNLGHVCRKLKKYAEALDYHRQALVL 380
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALAL 28
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
220-337 1.66e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 1.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 220 HKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAayftaaqlmkgchlpmlyigleygltnnsklaerfFGQ 299
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-----------------------------------LEK 50

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 568953496 300 ALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEK 337
Cdd:COG3063   51 ALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 369-438 2.89e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 2.89e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 369 EALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHcIEMYIGDSEA 438
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAE-ALLAAGDTEE 69
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 291-382 3.64e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.51  E-value: 3.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 291 KLAErffgQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALekikAIGNEVTVDKWepllnnLGHVCRKLKKYAEA 370
Cdd:COG3071  245 KRAE----KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAAL----ALRPSAEAYAE------LARLLEQLGDPEEA 310

                         90
                 ....*....|..
gi 568953496 371 LDYHRQALVLIP 382
Cdd:COG3071  311 AEHYRKALALAL 322
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 385-418 4.64e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 4.64e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 568953496   385 ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 418
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
354-378 5.09e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 34.79  E-value: 5.09e-03
                          10        20
                  ....*....|....*....|....*
gi 568953496  354 LNNLGHVCRKLKKYAEALDYHRQAL 378
Cdd:pfam13374   5 LNNLANALRAQGRYDEAEELLEEAL 29
TPR_1 pfam00515
Tetratricopeptide repeat;
385-418 5.92e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.32  E-value: 5.92e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 568953496  385 ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 418
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 367-421 6.02e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 38.76  E-value: 6.02e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568953496 367 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 421
Cdd:cd24142   16 FELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 183-269 6.03e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 6.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568953496 183 ELNKANELFylsHKLVDLYPSNPVSWFAVGCYYLMVGHKNEhARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAA 262
Cdd:COG5010   69 DFEESLALL---EQALQLDPNNPELYYNLALLYSRSGDKDE-AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                 ....*..
gi 568953496 263 YFTAAQL 269
Cdd:COG5010  145 LQRALGT 151
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 367-414 6.26e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 6.26e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 568953496 367 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 414
Cdd:PRK02603  51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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