|
Name |
Accession |
Description |
Interval |
E-value |
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
26-143 |
6.41e-26 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 102.38 E-value: 6.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 26 DLQSKAWPRVRQFLQ--DQKPGSLVADIGCGTGKYLK--VNSQVHTLGCDYCGPLVEIARNR------GCEVMVCDNLNL 95
Cdd:COG2226 2 DRVAARYDGREALLAalGLRPGARVLDLGCGTGRLALalAERGARVTGVDISPEMLELARERaaeaglNVEFVVGDAEDL 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 568954128 96 PFRDQGFDAIISIGVIHHFstkERRIRAIKEMARVLAPGGQLMIYVWA 143
Cdd:COG2226 82 PFPDGSFDLVISSFVLHHL---PDPERALAEIARVLKPGGRLVVVDFS 126
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
48-135 |
1.73e-23 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 94.17 E-value: 1.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 48 VADIGCGTGKYL-----KVNSQVHtlGCDYCGPLVEIARNRG------CEVMVCDNLNLPFRDQGFDAIISIGVIHHFST 116
Cdd:pfam13649 1 VLDLGCGTGRLTlalarRGGARVT--GVDLSPEMLERARERAaeaglnVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLPD 78
|
90
....*....|....*....
gi 568954128 117 KERRiRAIKEMARVLAPGG 135
Cdd:pfam13649 79 PDLE-AALREIARVLKPGG 96
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
22-139 |
3.15e-15 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 74.97 E-value: 3.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 22 PYFTDLQSkawpRVRQFLQDQkPGSLVADIGCGTG---KYLK--VNSQVHTLGCDYCGPLVEIARNRGC------EVMVC 90
Cdd:PRK08317 2 PDFRRYRA----RTFELLAVQ-PGDRVLDVGCGPGndaRELArrVGPEGRVVGIDRSEAMLALAKERAAglgpnvEFVRG 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 568954128 91 DNLNLPFRDQGFDAIISIGVIHHFSTKERrirAIKEMARVLAPGGQLMI 139
Cdd:PRK08317 77 DADGLPFPDGSFDAVRSDRVLQHLEDPAR---ALAEIARVLRPGGRVVV 122
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
48-139 |
8.25e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 61.68 E-value: 8.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 48 VADIGCGTGKY---LKVNSQVHTLGCDYCGPLVEIARNR-------GCEVMVCDNLNLPF-RDQGFDAIISIGVIHHFst 116
Cdd:cd02440 2 VLDLGCGTGALalaLASGPGARVTGVDISPVALELARKAaaalladNVEVLKGDAEELPPeADESFDVIISDPPLHHL-- 79
|
90 100
....*....|....*....|...
gi 568954128 117 KERRIRAIKEMARVLAPGGQLMI 139
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVL 102
|
|
| MenG_MenH_UbiE |
TIGR01934 |
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ... |
13-139 |
1.90e-11 |
|
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273884 [Multi-domain] Cd Length: 223 Bit Score: 63.44 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 13 VHSVYENTAPYFTDL-------QSKAWprvRQFLQDQ---KPGSLVADIGCGTG----KYLKVNSQV-HTLGCDYCGPLV 77
Cdd:TIGR01934 1 VQEMFDRIAPKYDLLndllsfgLHRLW---RRRAVKLigvFKGQKVLDVACGTGdlaiELAKSAPDRgKVTGVDFSSEML 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568954128 78 EIARNRGC-----EVMVCDNLNLPFRDQGFDAI-ISIGvIHHFStkeRRIRAIKEMARVLAPGGQLMI 139
Cdd:TIGR01934 78 EVAKKKSElplniEFIQADAEALPFEDNSFDAVtIAFG-LRNVT---DIQKALREMYRVLKPGGRLVI 141
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
26-143 |
6.41e-26 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 102.38 E-value: 6.41e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 26 DLQSKAWPRVRQFLQ--DQKPGSLVADIGCGTGKYLK--VNSQVHTLGCDYCGPLVEIARNR------GCEVMVCDNLNL 95
Cdd:COG2226 2 DRVAARYDGREALLAalGLRPGARVLDLGCGTGRLALalAERGARVTGVDISPEMLELARERaaeaglNVEFVVGDAEDL 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 568954128 96 PFRDQGFDAIISIGVIHHFstkERRIRAIKEMARVLAPGGQLMIYVWA 143
Cdd:COG2226 82 PFPDGSFDLVISSFVLHHL---PDPERALAEIARVLKPGGRLVVVDFS 126
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
48-135 |
1.73e-23 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 94.17 E-value: 1.73e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 48 VADIGCGTGKYL-----KVNSQVHtlGCDYCGPLVEIARNRG------CEVMVCDNLNLPFRDQGFDAIISIGVIHHFST 116
Cdd:pfam13649 1 VLDLGCGTGRLTlalarRGGARVT--GVDLSPEMLERARERAaeaglnVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLPD 78
|
90
....*....|....*....
gi 568954128 117 KERRiRAIKEMARVLAPGG 135
Cdd:pfam13649 79 PDLE-AALREIARVLKPGG 96
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
50-139 |
2.94e-20 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 85.02 E-value: 2.94e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 50 DIGCGTGKYLKVNSQV--HTLGCDYCGPLVEIAR----NRGCEVMVCDNLNLPFRDQGFDAIISIGVIHHFstkERRIRA 123
Cdd:pfam08241 2 DVGCGTGLLTELLARLgaRVTGVDISPEMLELARekapREGLTFVVGDAEDLPFPDNSFDLVLSSEVLHHV---EDPERA 78
|
90
....*....|....*.
gi 568954128 124 IKEMARVLAPGGQLMI 139
Cdd:pfam08241 79 LREIARVLKPGGILII 94
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
25-139 |
4.74e-19 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 82.76 E-value: 4.74e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 25 TDLQSKAW-PRVRQFLQDQ-KPGSLVADIGCGTGKYLKV----NSQVHtlGCDYCGPLVEIARNR----GCEVMVCDNLN 94
Cdd:COG2227 3 DPDARDFWdRRLAALLARLlPAGGRVLDVGCGTGRLALAlarrGADVT--GVDISPEALEIARERaaelNVDFVQGDLED 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 568954128 95 LPFRDQGFDAIISIGVIHHFstkERRIRAIKEMARVLAPGGQLMI 139
Cdd:COG2227 81 LPLEDGSFDLVICSEVLEHL---PDPAALLRELARLLKPGGLLLL 122
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
23-152 |
5.46e-19 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 84.97 E-value: 5.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 23 YFTDLQSKAWPRVRQFLQDQKPGSLVADIGCGTGKYL-----KVNSQVhtLGCDYCGPLVEIARNR-------GCEVMVC 90
Cdd:COG0500 5 YYSDELLPGLAALLALLERLPKGGRVLDLGCGTGRNLlalaaRFGGRV--IGIDLSPEAIALARARaakaglgNVEFLVA 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568954128 91 DNLNL-PFRDQGFDAIISIGVIHHFStKERRIRAIKEMARVLAPGGQLMIYVWAMEQKNRRFE 152
Cdd:COG0500 83 DLAELdPLPAESFDLVVAFGVLHHLP-PEEREALLRELARALKPGGVLLLSASDAAAALSLAR 144
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
22-139 |
3.15e-15 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 74.97 E-value: 3.15e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 22 PYFTDLQSkawpRVRQFLQDQkPGSLVADIGCGTG---KYLK--VNSQVHTLGCDYCGPLVEIARNRGC------EVMVC 90
Cdd:PRK08317 2 PDFRRYRA----RTFELLAVQ-PGDRVLDVGCGPGndaRELArrVGPEGRVVGIDRSEAMLALAKERAAglgpnvEFVRG 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 568954128 91 DNLNLPFRDQGFDAIISIGVIHHFSTKERrirAIKEMARVLAPGGQLMI 139
Cdd:PRK08317 77 DADGLPFPDGSFDAVRSDRVLQHLEDPAR---ALAEIARVLRPGGRVVV 122
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
13-139 |
4.00e-15 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 74.42 E-value: 4.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 13 VHSVYENTAP-YftDL--------QSKAWprvRQFLQDQ---KPGSLVADIGCGTGKYL-----KVNSQVHTLGCDYCGP 75
Cdd:PRK00216 13 VAEMFDSIAPkY--DLmndllsfgLHRVW---RRKTIKWlgvRPGDKVLDLACGTGDLAialakAVGKTGEVVGLDFSEG 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568954128 76 LVEIARNR--------GCEVMVCDNLNLPFRDQGFDAI-ISIG---VIHhfstkerRIRAIKEMARVLAPGGQLMI 139
Cdd:PRK00216 88 MLAVGREKlrdlglsgNVEFVQGDAEALPFPDNSFDAVtIAFGlrnVPD-------IDKALREMYRVLKPGGRLVI 156
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
43-141 |
1.80e-14 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 70.73 E-value: 1.80e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 43 KPGSLVADIGCGTG---KYLKVNSQVHTLGCDYCGPLVEIARNR--------GCEVMVCDNLNLPFrDQGFDAIISIGVI 111
Cdd:COG2230 50 KPGMRVLDIGCGWGglaLYLARRYGVRVTGVTLSPEQLEYARERaaeagladRVEVRLADYRDLPA-DGQFDAIVSIGMF 128
|
90 100 110
....*....|....*....|....*....|
gi 568954128 112 HHFSTKERRiRAIKEMARVLAPGGQLMIYV 141
Cdd:COG2230 129 EHVGPENYP-AYFAKVARLLKPGGRLLLHT 157
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
44-141 |
9.13e-14 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 66.77 E-value: 9.13e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 44 PGSLVADIGCGTGKYLKV----NSQVHTLGCDYCGPLVEIARNR--GCEVMVCDNLNLPFrDQGFDAIISIGVIHHFstk 117
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALlaerFPGARVTGVDLSPEMLARARARlpNVRFVVADLRDLDP-PEPFDLVVSNAALHWL--- 76
|
90 100
....*....|....*....|....
gi 568954128 118 ERRIRAIKEMARVLAPGGQLMIYV 141
Cdd:COG4106 77 PDHAALLARLAAALAPGGVLAVQV 100
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
10-155 |
9.78e-14 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 69.26 E-value: 9.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 10 KRHVHSVYENTAPYF-----TDLQSKAWPRVRQFLQDQ---KPGSLVADIGCGTG---KYLKvNSQVHTLGCDYCGPLVE 78
Cdd:COG4976 4 DAYVEALFDQYADSYdaalvEDLGYEAPALLAEELLARlppGPFGRVLDLGCGTGllgEALR-PRGYRLTGVDLSEEMLA 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568954128 79 IARNRGC--EVMVCDNLNLPFRDQGFDAIISIGVIHHFstkERRIRAIKEMARVLAPGGQLMIYVWAMEQKNRRFEKQD 155
Cdd:COG4976 83 KAREKGVydRLLVADLADLAEPDGRFDLIVAADVLTYL---GDLAAVFAGVARALKPGGLFIFSVEDADGSGRYAHSLD 158
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
50-137 |
6.10e-12 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 61.61 E-value: 6.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 50 DIGCGTG----KYLKVNSQVHTLGCDYCGPLVEIARNR--GCEVMVCDNLNLPFRD------QGFDAIISIGVIHHFSTK 117
Cdd:pfam08242 2 EIGCGTGtllrALLEALPGLEYTGLDISPAALEAARERlaALGLLNAVRVELFQLDlgeldpGSFDVVVASNVLHHLADP 81
|
90 100
....*....|....*....|
gi 568954128 118 ErriRAIKEMARVLAPGGQL 137
Cdd:pfam08242 82 R---AVLRNIRRLLKPGGVL 98
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
48-139 |
8.25e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 61.68 E-value: 8.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 48 VADIGCGTGKY---LKVNSQVHTLGCDYCGPLVEIARNR-------GCEVMVCDNLNLPF-RDQGFDAIISIGVIHHFst 116
Cdd:cd02440 2 VLDLGCGTGALalaLASGPGARVTGVDISPVALELARKAaaalladNVEVLKGDAEELPPeADESFDVIISDPPLHHL-- 79
|
90 100
....*....|....*....|...
gi 568954128 117 KERRIRAIKEMARVLAPGGQLMI 139
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVL 102
|
|
| MenG_MenH_UbiE |
TIGR01934 |
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ... |
13-139 |
1.90e-11 |
|
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273884 [Multi-domain] Cd Length: 223 Bit Score: 63.44 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 13 VHSVYENTAPYFTDL-------QSKAWprvRQFLQDQ---KPGSLVADIGCGTG----KYLKVNSQV-HTLGCDYCGPLV 77
Cdd:TIGR01934 1 VQEMFDRIAPKYDLLndllsfgLHRLW---RRRAVKLigvFKGQKVLDVACGTGdlaiELAKSAPDRgKVTGVDFSSEML 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568954128 78 EIARNRGC-----EVMVCDNLNLPFRDQGFDAI-ISIGvIHHFStkeRRIRAIKEMARVLAPGGQLMI 139
Cdd:TIGR01934 78 EVAKKKSElplniEFIQADAEALPFEDNSFDAVtIAFG-LRNVT---DIQKALREMYRVLKPGGRLVI 141
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
43-139 |
7.76e-11 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 60.12 E-value: 7.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 43 KPGSLVADIGCGTGKYL-----KVNSQVHTLGCDYCGPLVEIARNR-------GCEVMVCDNLNLP--FRDQGFDAIISI 108
Cdd:pfam13847 2 DKGMRVLDLGCGTGHLSfelaeELGPNAEVVGIDISEEAIEKARENaqklgfdNVEFEQGDIEELPelLEDDKFDVVISN 81
|
90 100 110
....*....|....*....|....*....|.
gi 568954128 109 GVIHHFSTKErriRAIKEMARVLAPGGQLMI 139
Cdd:pfam13847 82 CVLNHIPDPD---KVLQEILRVLKPGGRLII 109
|
|
| BioC |
TIGR02072 |
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ... |
48-138 |
6.48e-08 |
|
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]
Pssm-ID: 273953 [Multi-domain] Cd Length: 240 Bit Score: 53.44 E-value: 6.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 48 VADIGCGTG----KYLKVNSQVHTLGCDYCGPLVEIARNRGCEVM--VCDNL-NLPFRDQGFDAIISIGVIHHFSTKErr 120
Cdd:TIGR02072 38 VLDIGCGTGyltrALLKRFPQAEFIALDISAGMLAQAKTKLSENVqfICGDAeKLPLEDSSFDLIVSNLALQWCDDLS-- 115
|
90
....*....|....*...
gi 568954128 121 iRAIKEMARVLAPGGQLM 138
Cdd:TIGR02072 116 -QALSELARVLKPGGLLA 132
|
|
| COG4627 |
COG4627 |
Predicted SAM-depedendent methyltransferase [General function prediction only]; |
59-141 |
3.26e-07 |
|
Predicted SAM-depedendent methyltransferase [General function prediction only];
Pssm-ID: 443666 [Multi-domain] Cd Length: 161 Bit Score: 49.86 E-value: 3.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 59 LKVNsqvhtLGC--DYCGPLVEIARNRGCEVMVCDNLN--LPFRDQGFDAIISIGVIHHFsTKERRIRAIKEMARVLAPG 134
Cdd:COG4627 5 LKLN-----IGCgpKRLPGWLNVDIVPAPGVDIVGDLTdpLPFPDNSVDAIYSSHVLEHL-DYEEAPLALKECYRVLKPG 78
|
....*..
gi 568954128 135 GQLMIYV 141
Cdd:COG4627 79 GILRIVV 85
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
41-168 |
3.62e-07 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 51.67 E-value: 3.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 41 DQKPGSLVADIGCGTG---KYL--KVNSQVH--TLGCDYCGPLVEIARNRG----CEVMVCDNLNLPFRDQGFDAIISIG 109
Cdd:PLN02244 115 DEKRPKRIVDVGCGIGgssRYLarKYGANVKgiTLSPVQAARANALAAAQGlsdkVSFQVADALNQPFEDGQFDLVWSME 194
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 110 VIHHFSTKERrirAIKEMARVLAPGGQLMIYVWAmeqkNRRFEK-QDVLVPWNRALCSRL 168
Cdd:PLN02244 195 SGEHMPDKRK---FVQELARVAAPGGRIIIVTWC----HRDLEPgETSLKPDEQKLLDKI 247
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
36-150 |
5.36e-07 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 49.35 E-value: 5.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 36 RQFLQDQKPGSLVaDIGCGTGKYLKVNSQVhtlGCDYCGplVEIARNRGCEVMVC------DNLNLPFRDQGFDAIISIG 109
Cdd:pfam13489 15 RLLPKLPSPGRVL-DFGCGTGIFLRLLRAQ---GFSVTG--VDPSPIAIERALLNvrfdqfDEQEAAVPAGKFDVIVARE 88
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 568954128 110 VIHHFSTKerrIRAIKEMARVLAPGGQLMIYVWAMEQKNRR 150
Cdd:pfam13489 89 VLEHVPDP---PALLRQIAALLKPGGLLLLSTPLASDEADR 126
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
43-135 |
1.57e-06 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 48.02 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 43 KPGSLVADIGCGTG------KYLKVNSqvhtLGCDYCGPLVEIAR-------NRGCEVMVCDNLNLPFRDQGFDAIIS-- 107
Cdd:COG1041 25 KEGDTVLDPFCGTGtilieaGLLGRRV----IGSDIDPKMVEGARenlehygYEDADVIRGDARDLPLADESVDAIVTdp 100
|
90 100 110
....*....|....*....|....*....|..
gi 568954128 108 -IGVIHHFSTKERRI---RAIKEMARVLAPGG 135
Cdd:COG1041 101 pYGRSSKISGEELLElyeKALEEAARVLKPGG 132
|
|
| PLN02233 |
PLN02233 |
ubiquinone biosynthesis methyltransferase |
16-139 |
9.04e-06 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 177877 [Multi-domain] Cd Length: 261 Bit Score: 47.19 E-value: 9.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 16 VYENTAPYFTDLQSKAWPRVRQFLQDQKPGSLVADIGCGTGK--YL---KVNSQVHTLGCDYCGPLVEIA------RNRG 84
Cdd:PLN02233 45 VYDNLNDLLSLGQHRIWKRMAVSWSGAKMGDRVLDLCCGSGDlaFLlseKVGSDGKVMGLDFSSEQLAVAasrqelKAKS 124
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 568954128 85 C----EVMVCDNLNLPFRDQGFDAIiSIGviHHFSTKERRIRAIKEMARVLAPGGQLMI 139
Cdd:PLN02233 125 CykniEWIEGDATDLPFDDCYFDAI-TMG--YGLRNVVDRLKAMQEMYRVLKPGSRVSI 180
|
|
| Ubie_methyltran |
pfam01209 |
ubiE/COQ5 methyltransferase family; |
28-137 |
1.11e-05 |
|
ubiE/COQ5 methyltransferase family;
Pssm-ID: 395966 [Multi-domain] Cd Length: 228 Bit Score: 46.28 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 28 QSKAWPRVRQFLQDQKPGSLVADIGCGTG----KYLK-VNSQVHTLGCDYCGPLVEIARNRGCEV------MVCDN-LNL 95
Cdd:pfam01209 26 IHRLWKDFTMKCMGVKRGNKFLDVAGGTGdwtfGLSDsAGSSGKVVGLDINENMLKEGEKKAKEEgkynieFLQGNaEEL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 568954128 96 PFRDQGFDAI-ISIGvIHHFSTkerRIRAIKEMARVLAPGGQL 137
Cdd:pfam01209 106 PFEDDSFDIVtISFG-LRNFPD---YLKVLKEAFRVLKPGGRV 144
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
41-139 |
3.48e-05 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 45.90 E-value: 3.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 41 DQKPGSLVADIGCGTGK---YLKVNSQVHTLGCDYCGPLVEIA------RNRGCEVMVCDNLNLPFRDQGFDAIISIGVI 111
Cdd:PLN02336 263 DLKPGQKVLDVGCGIGGgdfYMAENFDVHVVGIDLSVNMISFAleraigRKCSVEFEVADCTKKTYPDNSFDVIYSRDTI 342
|
90 100
....*....|....*....|....*...
gi 568954128 112 HHFSTKERRIRAikeMARVLAPGGQLMI 139
Cdd:PLN02336 343 LHIQDKPALFRS---FFKWLKPGGKVLI 367
|
|
| PTZ00098 |
PTZ00098 |
phosphoethanolamine N-methyltransferase; Provisional |
44-139 |
1.00e-04 |
|
phosphoethanolamine N-methyltransferase; Provisional
Pssm-ID: 173391 [Multi-domain] Cd Length: 263 Bit Score: 43.81 E-value: 1.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 44 PGSLVADIGCGTG---KYLKVNSQVHTLGCDYCGPLVEIA--RNRG---CEVMVCDNLNLPFRDQGFDAIISIGVIHHFS 115
Cdd:PTZ00098 52 ENSKVLDIGSGLGggcKYINEKYGAHVHGVDICEKMVNIAklRNSDknkIEFEANDILKKDFPENTFDMIYSRDAILHLS 131
|
90 100
....*....|....*....|....
gi 568954128 116 TKERRiRAIKEMARVLAPGGQLMI 139
Cdd:PTZ00098 132 YADKK-KLFEKCYKWLKPNGILLI 154
|
|
| arsM |
PRK11873 |
arsenite methyltransferase; |
43-139 |
7.46e-04 |
|
arsenite methyltransferase;
Pssm-ID: 237007 [Multi-domain] Cd Length: 272 Bit Score: 41.09 E-value: 7.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 43 KPGSLVADIGCGTGK--YL---KVNSQVHTLGCDYCGPLVEIARN----RG---CEVMVCDNLNLPFRDQGFDAIISIGV 110
Cdd:PRK11873 76 KPGETVLDLGSGGGFdcFLaarRVGPTGKVIGVDMTPEMLAKARAnarkAGytnVEFRLGEIEALPVADNSVDVIISNCV 155
|
90 100
....*....|....*....|....*....
gi 568954128 111 IHHFSTKErriRAIKEMARVLAPGGQLMI 139
Cdd:PRK11873 156 INLSPDKE---RVFKEAFRVLKPGGRFAI 181
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
37-139 |
7.80e-04 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 40.56 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 37 QFLQDQKPGSlVADIGCGTG----KYLKVNSQVHTLGCDYCGPLVEIAR-N------RGCEVMVCDNLNlPFRDQGFDAI 105
Cdd:COG2813 43 EHLPEPLGGR-VLDLGCGYGviglALAKRNPEARVTLVDVNARAVELARaNaaanglENVEVLWSDGLS-GVPDGSFDLI 120
|
90 100 110
....*....|....*....|....*....|....*....
gi 568954128 106 IS-----IGVIHHFSTKERRIRAIkemARVLAPGGQLMI 139
Cdd:COG2813 121 LSnppfhAGRAVDKEVAHALIADA---ARHLRPGGELWL 156
|
|
| rrmA |
PRK11088 |
23S rRNA methyltransferase A; Provisional |
34-137 |
8.44e-04 |
|
23S rRNA methyltransferase A; Provisional
Pssm-ID: 236841 [Multi-domain] Cd Length: 272 Bit Score: 41.05 E-value: 8.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 34 RVRQFLQDQKPGS--LVADIGCGTGKY----LKVNSQVHTL---GCDYCGPLVEIARNR--GCEVMVCDNLNLPFRDQGF 102
Cdd:PRK11088 73 AVANLLAERLDEKatALLDIGCGEGYYthalADALPEITTMqlfGLDISKVAIKYAAKRypQVTFCVASSHRLPFADQSL 152
|
90 100 110
....*....|....*....|....*....|....*...
gi 568954128 103 DAIIsigvihhfstkerRIRA---IKEMARVLAPGGQL 137
Cdd:PRK11088 153 DAII-------------RIYApckAEELARVVKPGGIV 177
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
43-139 |
1.52e-03 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 40.39 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 43 KPGSLVADIGCGTG---KYLKVNSQVHTLGC-------DYCGPLV-EIARNRGCEVMVCDNLNLpfrDQGFDAIISIGVI 111
Cdd:pfam02353 60 KPGMTLLDIGCGWGglmRRAAERYDVNVVGLtlsknqyKLARKRVaAEGLARKVEVLLQDYRDF---DEPFDRIVSVGMF 136
|
90 100
....*....|....*....|....*...
gi 568954128 112 HHFStKERRIRAIKEMARVLAPGGQLMI 139
Cdd:pfam02353 137 EHVG-HENYDTFFKKLYNLLPPGGLMLL 163
|
|
| PLN02232 |
PLN02232 |
ubiquinone biosynthesis methyltransferase |
91-139 |
6.79e-03 |
|
ubiquinone biosynthesis methyltransferase
Pssm-ID: 165876 Cd Length: 160 Bit Score: 37.36 E-value: 6.79e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 568954128 91 DNLNLPFRDQGFDAIiSIGviHHFSTKERRIRAIKEMARVLAPGGQLMI 139
Cdd:PLN02232 34 DAIDLPFDDCEFDAV-TMG--YGLRNVVDRLRAMKEMYRVLKPGSRVSI 79
|
|
| PRK05785 |
PRK05785 |
hypothetical protein; Provisional |
11-130 |
6.99e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235607 [Multi-domain] Cd Length: 226 Bit Score: 37.74 E-value: 6.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 11 RHVHSVYENTAPYFTDLQSKAWPR--VRQFLQ-DQKPGsLVADIGCGTGK---YLKVNSQVHTLGCDYCGPLVEIARNRG 84
Cdd:PRK05785 16 NKIPKAYDRANRFISFNQDVRWRAelVKTILKyCGRPK-KVLDVAAGKGElsyHFKKVFKYYVVALDYAENMLKMNLVAD 94
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 568954128 85 CEVmVCDNLNLPFRDQGFDAIISIGVIHHFSTKErriRAIKEMARV 130
Cdd:PRK05785 95 DKV-VGSFEALPFRDKSFDVVMSSFALHASDNIE---KVIAEFTRV 136
|
|
| prmA |
PRK00517 |
50S ribosomal protein L11 methyltransferase; |
37-137 |
7.38e-03 |
|
50S ribosomal protein L11 methyltransferase;
Pssm-ID: 234786 [Multi-domain] Cd Length: 250 Bit Score: 37.82 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568954128 37 QFLQDQ-KPGSLVADIGCGTG------KYLKVNsqvHTLGCDYcGPL-VE-----IARNRgcevmVCDNLNLPFRDQGFD 103
Cdd:PRK00517 111 EALEKLvLPGKTVLDVGCGSGilaiaaAKLGAK---KVLAVDI-DPQaVEaarenAELNG-----VELNVYLPQGDLKAD 181
|
90 100 110
....*....|....*....|....*....|....*..
gi 568954128 104 AIIS-I--GVIhhfstkerrIRAIKEMARVLAPGGQL 137
Cdd:PRK00517 182 VIVAnIlaNPL---------LELAPDLARLLKPGGRL 209
|
|
|