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Conserved domains on  [gi|568979301|ref|XP_006515762|]
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ubiquinone biosynthesis monooxygenase COQ6, mitochondrial isoform X1 [Mus musculus]

Protein Classification

Rossmann-fold NAD(P)-binding domain-containing protein( domain architecture ID 229380)

Rossmann-fold NAD(P)-binding domain-containing protein may function as an oxidoreductase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NADB_Rossmann super family cl21454
Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a ...
 57-471 0e+00

Rossmann-fold NAD(P)(+)-binding proteins; A large family of proteins that share a Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The NADB domain is found in numerous dehydrogenases of metabolic pathways such as glycolysis, and many other redox enzymes. NAD binding involves numerous hydrogen-bonds and van der Waals contacts, in particular H-bonding of residues in a turn between the first strand and the subsequent helix of the Rossmann-fold topology. Characteristically, this turn exhibits a consensus binding pattern similar to GXGXXG, in which the first 2 glycines participate in NAD(P)-binding, and the third facilitates close packing of the helix to the beta-strand. Typically, proteins in this family contain a second domain in addition to the NADB domain, which is responsible for specifically binding a substrate and catalyzing a particular enzymatic reaction.


The actual alignment was detected with superfamily member TIGR01989:

Pssm-ID: 473865 [Multi-domain]  Cd Length: 437  Bit Score: 634.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301   57 AMACALGHDIHFHDKKILLLEAG--PKKA---LEKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDS 131
Cdd:TIGR01989  14 ALAAALGNNPLTKDLKVLLLDAVdnPKLKsrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  132 CSEALIMFDRDN-LDDMGYIVENDVIMYALTKQLEAV-ADRVKVLYESKAVGYSWPGAfSMADSSPWVHITLGDGSTLQT 209
Cdd:TIGR01989  94 CSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSK-YPNDNSNWVHITLSDGQVLYT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  210 KLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAEL 289
Cdd:TIGR01989 173 KLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRL 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  290 VSMDEEEFVDAINSAF---WSDVHHTDFVDSASAMVRHAVALLKPTKVSARQLPPSIAKVDAKSRALFPLGLGHAAEYVR 366
Cdd:TIGR01989 253 LSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVT 332

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  367 PRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSA 446
Cdd:TIGR01989 333 KRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDF 412

                         410       420
                  ....*....|....*....|....*
gi 568979301  447 TPLVLLRTWGLQATNAVSPLKEQIM 471
Cdd:TIGR01989 413 PPVVALRTFGLNLTNYIGPLKNFIM 437
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 57-471 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 634.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301   57 AMACALGHDIHFHDKKILLLEAG--PKKA---LEKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDS 131
Cdd:TIGR01989  14 ALAAALGNNPLTKDLKVLLLDAVdnPKLKsrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  132 CSEALIMFDRDN-LDDMGYIVENDVIMYALTKQLEAV-ADRVKVLYESKAVGYSWPGAfSMADSSPWVHITLGDGSTLQT 209
Cdd:TIGR01989  94 CSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSK-YPNDNSNWVHITLSDGQVLYT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  210 KLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAEL 289
Cdd:TIGR01989 173 KLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRL 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  290 VSMDEEEFVDAINSAF---WSDVHHTDFVDSASAMVRHAVALLKPTKVSARQLPPSIAKVDAKSRALFPLGLGHAAEYVR 366
Cdd:TIGR01989 253 LSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVT 332

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  367 PRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSA 446
Cdd:TIGR01989 333 KRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDF 412

                         410       420
                  ....*....|....*....|....*
gi 568979301  447 TPLVLLRTWGLQATNAVSPLKEQIM 471
Cdd:TIGR01989 413 PPVVALRTFGLNLTNYIGPLKNFIM 437
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 85-474 6.45e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 238.52  E-value: 6.45e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  85 EKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDRDNL--DDMGYIVENDVIMYALTK 162
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLALLE 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 163 QLEAvADRVKVLYESKAvgyswpGAFSMADSSPWvhITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVA 242
Cdd:PRK08850 120 QVQK-QDNVTLLMPARC------QSIAVGESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 243 TLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEEFVDAINSAFwsdvhhtdfvDSasam 321
Cdd:PRK08850 191 NVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEF----------DN---- 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 322 vrhavallkptkvsarQLppSIAKVDAkSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHL 401
Cdd:PRK08850 256 ----------------RL--GLCEVVG-ERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEI 316

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568979301 402 STAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKEQIMAFA 474
Cdd:PRK08850 317 LALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 57-467 7.59e-39

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 143.54  E-value: 7.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACALGHdiHFHDkkILLLEAGPkkaleklSETYSNRVSSISPGSTTLLSSFGAWDHICnMRCKAFRRMQVWDSCS-EA 135
Cdd:COG0654   17 ALALALAR--AGIR--VTVVERAP-------PPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDGSDgRV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 136 LIMFDRDNLD-DMGYIVENDVIMYALTKQLEAvaDRVKVLYESKAVGYSWPGAFsmadsspwVHITLGDGSTLQTKLLIG 214
Cdd:COG0654   85 LARFDAAETGlPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLEQDADG--------VTVTLADGRTLRADLVVG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 215 ADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLseatennvawqrflpsgpiallplsdtlsslvwstshehaaelvsmde 294
Cdd:COG0654  155 ADGARSAVRRLLGIGFTGRDYPQRALWAGVRT------------------------------------------------ 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 295 eEFVDAINSAFWsdvhhtdfvdsasamvrHAVALLkptkvsarqlppsiakvDAKSRALFPLGLGHAAEYVRPRVALIGD 374
Cdd:COG0654  187 -ELRARLAAAGP-----------------RLGELL-----------------ELSPRSAFPLRRRRAERWRRGRVVLLGD 231

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 375 AAHRIHPLAGQGVNMGFGDISSLVHHLStAAFNGKDLGSMshLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRT 454
Cdd:COG0654  232 AAHTMHPLGGQGANLALRDAAALAWKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRN 308

                        410
                 ....*....|...
gi 568979301 455 WGLQATNAVSPLK 467
Cdd:COG0654  309 AGLRLLDRLPPLK 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 202-435 2.08e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 58.88  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  202 GDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPLSDTLS 275
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  276 S---LVWSTSHEHAAELVSMDEEEFVDAINSAfwsdvHHTDFVDsasamvrhavallkptkvsarqlppsiAKVDAKSRa 352
Cdd:pfam01494 223 EryyVQVPWDEEVEERPEEFTDEELKQRLRSI-----VGIDLAL---------------------------VEILWKSI- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  353 lFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLStAAFNGKdlGSMSHLTGYETDRQRHNTALL 432
Cdd:pfam01494 270 -WGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVV 345


                  ...
gi 568979301  433 AAT 435
Cdd:pfam01494 346 DFA 348
 
Name Accession Description Interval E-value
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
 57-471 0e+00

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 634.49  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301   57 AMACALGHDIHFHDKKILLLEAG--PKKA---LEKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDS 131
Cdd:TIGR01989  14 ALAAALGNNPLTKDLKVLLLDAVdnPKLKsrnYEKPDGPYSNRVSSITPASISFFKKIGAWDHIQSDRIQPFGRMQVWDG 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  132 CSEALIMFDRDN-LDDMGYIVENDVIMYALTKQLEAV-ADRVKVLYESKAVGYSWPGAfSMADSSPWVHITLGDGSTLQT 209
Cdd:TIGR01989  94 CSLALIRFDRDNgKEDMACIIENDNIQNSLYNRLQEYnGDNVKILNPARLISVTIPSK-YPNDNSNWVHITLSDGQVLYT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  210 KLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAEL 289
Cdd:TIGR01989 173 KLLIGADGSNSNVRKAANIDTTGWNYNQHAVVATLKLEEATENDVAWQRFLPTGPIALLPLPDNNSTLVWSTSPEEALRL 252

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  290 VSMDEEEFVDAINSAF---WSDVHHTDFVDSASAMVRHAVALLKPTKVSARQLPPSIAKVDAKSRALFPLGLGHAAEYVR 366
Cdd:TIGR01989 253 LSLPPEDFVDALNAAFdlgYSDHPYSYLLDYAMEKLNEDIGFRTEGSKSCFQVPPRVIGVVDKSRAAFPLGLGHADEYVT 332

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  367 PRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSA 446
Cdd:TIGR01989 333 KRVALVGDAAHRVHPLAGQGVNLGFGDVASLVKALAEAVSVGADIGSISSLKPYERERYAKNVVLLGLVDKLHKLYATDF 412

                         410       420
                  ....*....|....*....|....*
gi 568979301  447 TPLVLLRTWGLQATNAVSPLKEQIM 471
Cdd:TIGR01989 413 PPVVALRTFGLNLTNYIGPLKNFIM 437
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
 57-475 1.51e-151

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 436.63  E-value: 1.51e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301   57 AMACALGHDIhfhdKKILLLEAGPkkALEKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEAL 136
Cdd:TIGR01988  13 ALALALARSG----LKVALIEATP--LPAPADPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSDGGSFGA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  137 IMFDRD--NLDDMGYIVENDVIMYALTKQLEavadrvkvlyESKAVGYSWPGAF-SMADSSPWVHITLGDGSTLQTKLLI 213
Cdd:TIGR01988  87 LRFDADeiGLEALGYVVENRVLQQALWERLQ----------ELPNVTLLCPARVvELPRHSDHVELTLDDGQQLRARLLV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  214 GADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATeNNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMD 293
Cdd:TIGR01988 157 GADGANSKVRQLAGIPTTGWDYGQSAVVANVKHERPH-QGTAWERFTPTGPLALLPLPDNRSSLVWTLPPEEAERLLALS 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  294 EEEFVDAINSAFWSdvhhtdfvdsasamvrhavallkptkvsarQLPPSiakVDAKSRALFPLGLGHAAEYVRPRVALIG 373
Cdd:TIGR01988 236 DEEFLAELQRAFGS------------------------------RLGAI---TLVGERHAFPLSLTHAKRYVAPRLALIG 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  374 DAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLR 453
Cdd:TIGR01988 283 DAAHTIHPLAGQGLNLGLRDVAALAEVLEDARRRGEDIGSLRVLQRYERRRRFDNAAMLGATDGLNRLFSNDFPPLRLLR 362

                         410       420
                  ....*....|....*....|..
gi 568979301  454 TWGLQATNAVSPLKEQIMAFAS 475
Cdd:TIGR01988 363 NLGLRLLNNLPPLKNFIARYAM 384
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
 85-474 6.45e-74

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 238.52  E-value: 6.45e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  85 EKLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDRDNL--DDMGYIVENDVIMYALTK 162
Cdd:PRK08850  40 EALNELPDVRVSALSRSSEHILRNLGAWQGIEARRAAPYIAMEVWEQDSFARIEFDAESMaqPDLGHIVENRVIQLALLE 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 163 QLEAvADRVKVLYESKAvgyswpGAFSMADSSPWvhITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVA 242
Cdd:PRK08850 120 QVQK-QDNVTLLMPARC------QSIAVGESEAW--LTLDNGQALTAKLVVGADGANSWLRRQMDIPLTHWDYGHSALVA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 243 TLHLSEaTENNVAWQRFLPSGPIALLPLSDT-LSSLVWSTSHEHAAELVSMDEEEFVDAINSAFwsdvhhtdfvDSasam 321
Cdd:PRK08850 191 NVRTVD-PHNSVARQIFTPQGPLAFLPMSEPnMSSIVWSTEPLRAEALLAMSDEQFNKALTAEF----------DN---- 255

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 322 vrhavallkptkvsarQLppSIAKVDAkSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHL 401
Cdd:PRK08850 256 ----------------RL--GLCEVVG-ERQAFPLKMRYARDFVRERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEI 316

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568979301 402 STAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKEQIMAFA 474
Cdd:PRK08850 317 LALWQQGRDIGLKRNLRGYERWRKAEAAKMIAAMQGFRDLFSGSNPAKKLVRGIGMSLAGQLPGAKDEIMKRA 389
PRK07364 PRK07364
FAD-dependent hydroxylase;
58-467 2.36e-70

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 229.52  E-value: 2.36e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  58 MACALGHDihfhDKKILLLEAGPKKALEKLSETYSnrvssISPGSTTLLSSFGAWDHICNmRCKAFRRMQVWDSCSEALI 137
Cdd:PRK07364  33 LAAALKDS----GLRIALIEAQPAEAAAAKGQAYA-----LSLLSARIFEGIGVWEKILP-QIGKFRQIRLSDADYPGVV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 138 MFDRDNL--DDMGYIVENDVIMYALTKQLEAvADRVKVLYESKAVGYSWPGAFsmadsspwVHITL---GDGSTLQTKLL 212
Cdd:PRK07364 103 KFQPTDLgtEALGYVGEHQVLLEALQEFLQS-CPNITWLCPAEVVSVEYQQDA--------ATVTLeieGKQQTLQSKLV 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 213 IGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSM 292
Cdd:PRK07364 174 VAADGARSPIRQAAGIKTKGWKYWQSCVTATVKH-EAPHNDIAYERFWPSGPFAILPLPGNRCQIVWTAPHAQAKALLAL 252

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 293 DEEEFvdainsafwsdvhhtdfvdsasamvrhaVALLKptkvsaRQLPPSIAKVDAKS-RALFPLGLGHAAEYVRPRVAL 371
Cdd:PRK07364 253 PEAEF----------------------------LAELQ------QRYGDQLGKLELLGdRFLFPVQLMQSDRYVQHRLAL 298

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 372 IGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVL 451
Cdd:PRK07364 299 VGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTAHQRGEDIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQWWPLVV 378

                        410
                 ....*....|....*.
gi 568979301 452 LRTWGLQATNAVSPLK 467
Cdd:PRK07364 379 VRRLGLWLLRHVPPLK 394
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
57-475 9.30e-67

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 219.06  E-value: 9.30e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACALGHDihfhDKKILLLEAGPKKALEklSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDScSEAL 136
Cdd:PRK07608  19 SLALALAQS----GLRVALLAPRAPPRPA--DDAWDSRVYAISPSSQAFLERLGVWQALDAARLAPVYDMRVFGD-AHAR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 137 IMFD--RDNLDDMGYIVENDVIMYALTKQLeAVADRVKVLYESkavgyswPGAFSMADSSpwVHITLGDGSTLQTKLLIG 214
Cdd:PRK07608  92 LHFSayQAGVPQLAWIVESSLIERALWAAL-RFQPNLTWFPAR-------AQGLEVDPDA--ATLTLADGQVLRADLVVG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 215 ADGHKSGVRQAAGIQNVSWKYDQSAVVATLhLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDE 294
Cdd:PRK07608 162 ADGAHSWVRSQAGIKAERRPYRQTGVVANF-KAERPHRGTAYQWFRDDGILALLPLPDGHVSMVWSARTAHADELLALSP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 295 EEFVDAinsafwsdvhhtdfVDSASAMVRHAVALLKPtkvsarqlppsiakvdaksRALFPLGLGHAAEYVRPRVALIGD 374
Cdd:PRK07608 241 EALAAR--------------VERASGGRLGRLECVTP-------------------AAGFPLRLQRVDRLVAPRVALVGD 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 375 AAHRIHPLAGQGVNMGFGDISSLVHHL-STAAFngKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLR 453
Cdd:PRK07608 288 AAHLIHPLAGQGMNLGLRDVAALADVLaGREPF--RDLGDLRLLRRYERARREDILALQVATDGLQRLFALPGPLARWLR 365

                        410       420
                 ....*....|....*....|..
gi 568979301 454 TWGLQATNAVSPLKEQIMAFAS 475
Cdd:PRK07608 366 NAGMALVGALPLVKRWLVRHAL 387
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
70-468 1.13e-66

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 219.47  E-value: 1.13e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  70 DKKILLLEAGPKKALEKlsetySNRVSSISPGSTTLLSSFGAWDHICNmRCKAFRRMQVWDSCSE-----ALIMFDRDNL 144
Cdd:PRK07333  26 HLPVTVVDAAPAGAWSR-----DPRASAIAAAARRMLEALGVWDEIAP-EAQPITDMVITDSRTSdpvrpVFLTFEGEVE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 145 DD--MGYIVENDVIMYALTKQLEAVAdrVKVLYESKAVGyswpgaFSMADSSpwVHITLGDGSTLQTKLLIGADGHKSGV 222
Cdd:PRK07333 100 PGepFAHMVENRVLINALRKRAEALG--IDLREATSVTD------FETRDEG--VTVTLSDGSVLEARLLVAADGARSKL 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 223 RQAAGIQNVSWKYDQSAVVATL-HlsEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEEFVDAI 301
Cdd:PRK07333 170 RELAGIKTVGWDYGQSGIVCTVeH--ERPHGGRAEEHFLPAGPFAILPLKGNRSSLVWTERTADAERLVALDDLVFEAEL 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 302 NSAFWsdvHHTDFVdsasamvrhavallkptkvsarqlppsiaKVDAKSRAlFPLGLGHAAEYVRPRVALIGDAAHRIHP 381
Cdd:PRK07333 248 EQRFG---HRLGEL-----------------------------KVLGKRRA-FPLGLTLARSFVAPRFALVGDAAHGIHP 294

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 382 LAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATN 461
Cdd:PRK07333 295 IAGQGLNLGLKDVAALAEVVVEAARLGLDIGSLDVLERYQRWRRFDTVRMGVTTDVLNRLFSNDSTLLRSVRDIGLGLVD 374


                 ....*..
gi 568979301 462 AVSPLKE 468
Cdd:PRK07333 375 RLPKLKS 381
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 94-474 1.77e-66

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 218.70  E-value: 1.77e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  94 RVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSeALIMFDRD--NLDDMGYIVENDVIMYALTKQLEAvADRV 171
Cdd:PRK08020  51 RISAISAASVALLKGLGVWDAVQAMRSHPYRRLETWEWET-AHVVFDAAelKLPELGYMVENRVLQLALWQALEA-HPNV 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 172 KVLYESKAVGYSWpgafsmaDSSPWvHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHlSEATE 251
Cdd:PRK08020 129 TLRCPASLQALQR-------DDDGW-ELTLADGEEIQAKLVIGADGANSQVRQMAGIGVHGWQYRQSCMLISVK-CENPP 199

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 252 NNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEEFVDAINSAFwsdvhhtdfvdsasamvrhavallkp 331
Cdd:PRK08020 200 GDSTWQQFTPSGPRAFLPLFDNWASLVWYDSPARIRQLQAMSMAQLQQEIAAHF-------------------------- 253

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 332 tkvsarqlPPSIAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDL 411
Cdd:PRK08020 254 --------PARLGAVTPVAAGAFPLTRRHALQYVQPGLALVGDAAHTINPLAGQGVNLGYRDVDALLDVLVNARSYGEAW 325

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568979301 412 GSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKEQIMAFA 474
Cdd:PRK08020 326 ASEAVLKRYQRRRMADNLLMQSGMDLFYAGFSNNLPPLRFARNLGLMAAQRAGVLKRQALKYA 388
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 71-474 4.39e-62

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 206.93  E-value: 4.39e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  71 KKILLLEAGPKKALEKlSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDScSEALIMFDRD--NLDDMG 148
Cdd:PRK08849  27 RSVAVIEGGEPKAFEP-SQPMDIRVSAISQTSVDLLESLGAWSSIVAMRVCPYKRLETWEH-PECRTRFHSDelNLDQLG 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 149 YIVENDVIMYALTKQLEAVaDRVKVLYESKavgyswpgafsMAD---SSPWVHITLGDGSTLQTKLLIGADGHKSGVRQA 225
Cdd:PRK08849 105 YIVENRLIQLGLWQQFAQY-PNLTLMCPEK-----------LADlefSAEGNRVTLESGAEIEAKWVIGADGANSQVRQL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 226 AGIQNVSWKYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEEFVDAInsaf 305
Cdd:PRK08849 173 AGIGITAWDYRQHCMLINVE-TEQPQQDITWQQFTPSGPRSFLPLCGNQGSLVWYDSPKRIKQLSAMNPEQLRSEI---- 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 306 wsdvhhtdfvdsasamVRHavallkptkvsarqLPPSIAKVDAKSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQ 385
Cdd:PRK08849 248 ----------------LRH--------------FPAELGEIKVLQHGSFPLTRRHAQQYVKNNCVLLGDAAHTINPLAGQ 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 386 GVNMGFGDISSLVHhlstaAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSP 465
Cdd:PRK08849 298 GVNLGFKDVDVLLA-----ETEKQGVLNDASFARYERRRRPDNLLMQTGMDLFYKTFSNSLTPLKFVRNAALKLAENSGP 372


                 ....*....
gi 568979301 466 LKEQIMAFA 474
Cdd:PRK08849 373 LKTQVLKYA 381
UbiH TIGR01984
2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent ...
 72-470 5.08e-62

2-polyprenyl-6-methoxyphenol 4-hydroxylase; This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273911 [Multi-domain]  Cd Length: 382  Bit Score: 206.78  E-value: 5.08e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301   72 KILLLEAGPKKALEKlseTYSNRVSSISPGSTTLLSSFGAWDHICNMRCkAFRRMQVWDSCSEALIMFDRD--NLDDMGY 149
Cdd:TIGR01984  25 KIALIEANSPSAAQP---GFDARSLALSYGSKQILEKLGLWPKLAPFAT-PILDIHVSDQGHFGATHLRASefGLPALGY 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  150 IVENDVIMYALTKQLeAVADRVKVLYESKAVGYswpgafsmADSSPWVHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQ 229
Cdd:TIGR01984 101 VVELADLGQALLSRL-ALLTNIQLYCPARYKEI--------IRNQDYVRVTLDNGQQLRAKLLIAADGANSKVRELLSIP 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  230 NVSWKYDQSAVVATLHLSEATENnVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAELVSMDEEEFVDAINSAFWSD 308
Cdd:TIGR01984 172 TEEHDYNQTALIANIRHEQPHQG-CAFERFTPHGPLALLPLKDnYRSSLVWCLPSKQADTIANLPDAEFLAELQQAFGWR 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  309 vhhtdfvdsasamvrhavaLLKPTKVSARQLppsiakvdaksralFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVN 388
Cdd:TIGR01984 251 -------------------LGKITQVGERKT--------------YPLKLRIAETHVHPRVVLIGNAAQTLHPIAGQGFN 297

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  389 MGFGDISSLVHHLSTAAfngKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKE 468
Cdd:TIGR01984 298 LGLRDVETLAEVLIDAR---IDLGTYALLQEYLRRRQFDQFITIGLTDGLNRLFSNHIPLLRALRNLGLLALENFPPLKK 374


                  ..
gi 568979301  469 QI 470
Cdd:TIGR01984 375 RL 376
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 57-467 7.57e-61

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 204.29  E-value: 7.57e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACALGHDihfhDKKILLLEAGPKKALE-KLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEA 135
Cdd:PRK05714  16 ALALALQGS----GLEVLLLDGGPLSVKPfDPQAPFEPRVSALSAASQRILERLGAWDGIAARRASPYSEMQVWDGSGTG 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 136 LIMFDRDNL--DDMGYIVENDVIMYALtkqLEAVAD-RVKVLYESKAVGYSWPGafsmadsSPWVhITLGDGSTLQTKLL 212
Cdd:PRK05714  92 QIHFSAASVhaEVLGHIVENRVVQDAL---LERLHDsDIGLLANARLEQMRRSG-------DDWL-LTLADGRQLRAPLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 213 IGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEAtENNVAWQRFLPSGPIALLPLSDT----LSSLVWSTSHEHAAE 288
Cdd:PRK05714 161 VAADGANSAVRRLAGCATREWDYLHHAIVTSVRCSEP-HRATAWQRFTDDGPLAFLPLERDgdehWCSIVWSTTPEEAER 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 289 LVSMDEEEFVDAINSAFWSDVHHTdfvdsasamvrhavallkptkvsarqlppsiakVDAKSRALFPLGLGHAAEYVRPR 368
Cdd:PRK05714 240 LMALDDDAFCAALERAFEGRLGEV---------------------------------LSADPRLCVPLRQRHAKRYVEPG 286

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 369 VALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATP 448
Cdd:PRK05714 287 LALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLHAAERGERLADVRVLSRFERRRMPHNLALMAAMEGFERLFQADPLP 366

                        410
                 ....*....|....*....
gi 568979301 449 LVLLRTWGLQATNAVSPLK 467
Cdd:PRK05714 367 LRWLRNTGLKLVDQMPEAK 385
PRK08013 PRK08013
oxidoreductase; Provisional
 57-471 6.10e-60

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 201.81  E-value: 6.10e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACAL-GHDIhfhdkKILLLEAGPKKALEkLSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEA 135
Cdd:PRK08013  17 AVACGLqGSGL-----RVAVLEQRVPEPLA-ADAPPALRVSAINAASEKLLTRLGVWQDILARRASCYHGMEVWDKDSFG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 136 LIMFDRDN--LDDMGYIVENDVIMYALTKQLEAVADrVKVLYES--KAVGYSWPGAFsmadsspwvhITLGDGSTLQTKL 211
Cdd:PRK08013  91 RIAFDDQSmgYSHLGHIIENSVIHYALWQKAQQSSD-ITLLAPAelQQVAWGENEAF----------LTLKDGSMLTARL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 212 LIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSD-TLSSLVWSTSHEHAAELV 290
Cdd:PRK08013 160 VVGADGANSWLRNKADIPLTFWDYQHHALVATIR-TEEPHDAVARQVFHGDGILAFLPLSDpHLCSIVWSLSPEEAQRMQ 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 291 SMDEEEFVDAINSAFwsDVHhtdfvdsasamvrhavaLLKPTKVSARQlppsiakvdaksraLFPLGLGHAAEYVRPRVA 370
Cdd:PRK08013 239 QAPEEEFNRALAIAF--DNR-----------------LGLCELESERQ--------------VFPLTGRYARQFAAHRLA 285

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 371 LIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLV 450
Cdd:PRK08013 286 LVGDAAHTIHPLAGQGVNLGFMDAAELIAELRRLHRQGKDIGQHLYLRRYERSRKHSAALMLAGMQGFRDLFAGNNPAKK 365

                        410       420
                 ....*....|....*....|.
gi 568979301 451 LLRTWGLQATNAVSPLKEQIM 471
Cdd:PRK08013 366 LLRDIGLKLADTLPGVKPQLI 386
PRK08773 PRK08773
UbiH/UbiF family hydroxylase;
94-466 1.46e-54

UbiH/UbiF family hydroxylase;


Pssm-ID: 181552 [Multi-domain]  Cd Length: 392  Bit Score: 187.38  E-value: 1.46e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  94 RVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDRDNL--DDMGYIVENDVIMYALTKQLEAVAdrV 171
Cdd:PRK08773  51 RVYAFAADNAALLDRLGVWPAVRAARAQPYRRMRVWDAGGGGELGFDADTLgrEQLGWIVENDLLVDRLWAALHAAG--V 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 172 KVLYESKAVgyswpgafSMADSSPWVHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVA---TLHLSE 248
Cdd:PRK08773 129 QLHCPARVV--------ALEQDADRVRLRLDDGRRLEAALAIAADGAASTLRELAGLPVSRHDYAQRGVVAfvdTEHPHQ 200

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 249 ATennvAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEEFVDAINSAFWSDVHHtdfVDSASAmvrhaval 328
Cdd:PRK08773 201 AT----AWQRFLPTGPLALLPFADGRSSIVWTLPDAEAERVLALDEAAFSRELTQAFAARLGE---VRVASP-------- 265

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 329 lkptkvsarqlppsiakvdaksRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNG 408
Cdd:PRK08773 266 ----------------------RTAFPLRRQLVQQYVSGRVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARR 323

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 568979301 409 KDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPL 466
Cdd:PRK08773 324 ADWAAPHRLQRWARTRRSDNTVAAYGFDAINRVFSNDEMHLTLLRGSVLGLAGKLPPL 381
PRK05732 PRK05732
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 59-467 1.37e-51

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 235584 [Multi-domain]  Cd Length: 395  Bit Score: 179.28  E-value: 1.37e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  59 ACALGHDIHfHDKKILLLEAgpKKALEKLSETYSNRVSSISPGSTTLLSSFGAWDHIcNMRCKAFRRMQVWDS--CSEAL 136
Cdd:PRK05732  19 ALALSRLSH-GGLPVALIEA--FAPESDAHPGFDARAIALAAGTCQQLARLGVWQAL-ADCATPITHIHVSDRghAGFVR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 137 IMFDRDNLDDMGYIVENDVIMYALTKQLEavadrvkvlyesKAVGYSW--PGAF-SMADSSPWVHITLGDGSTLQTKLLI 213
Cdd:PRK05732  95 LDAEDYGVPALGYVVELHDVGQRLFALLD------------KAPGVTLhcPARVaNVERTQGSVRVTLDDGETLTGRLLV 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 214 GADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEAtENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMD 293
Cdd:PRK05732 163 AADGSHSALREALGIDWQQHPYEQVAVIANVTTSEA-HQGRAFERFTEHGPLALLPMSDGRCSLVWCHPLEDAEEVLSWS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 294 EEEFVDAINSAF-WSdvhhtdfvdsasamvrhavaLLKPTKVSArqlppsiakvdaksRALFPLGLGHAAEYVRPRVALI 372
Cdd:PRK05732 242 DAQFLAELQQAFgWR--------------------LGRITHAGK--------------RSAYPLALVTAAQQISHRLALV 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 373 GDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQ--RHNTalLAATDLLKRLYSTSATPLV 450
Cdd:PRK05732 288 GNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDIGDYAVLQRYQQRRQqdREAT--IGFTDGLVRLFANRWAPLV 365

                        410
                 ....*....|....*..
gi 568979301 451 LLRTWGLQATNAVSPLK 467
Cdd:PRK05732 366 VGRNLGLMAMDLLPPAR 382
PRK09126 PRK09126
FAD-dependent hydroxylase;
72-470 3.57e-43

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 157.03  E-value: 3.57e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  72 KILLLEAGPKKALEklSETYSNRVSSISPGSTTLLSSFGAWDHICNMRCKAFRRMQVWDSCSEALIMFDRDN--LDDMGY 149
Cdd:PRK09126  28 KVTLIERQPLAALA--DPAFDGREIALTHASREILQRLGAWDRIPEDEISPLRDAKVLNGRSPFALTFDARGrgADALGY 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 150 IVENDVIMYALtkqLEAVADRVKV-LYESKAVGYSWPGAfsmadssPWVHITLGDGSTLQTKLLIGADGHKSGVRQAAGI 228
Cdd:PRK09126 106 LVPNHLIRRAA---YEAVSQQDGIeLLTGTRVTAVRTDD-------DGAQVTLANGRRLTARLLVAADSRFSATRRQLGI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 229 QNVSWKYDQSAVVATLHlSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEEFVDAInsafwsd 308
Cdd:PRK09126 176 GADMHDFGRTMLVCRMR-HELPHHHTAWEWFGYGQTLALLPLNGHLSSLVLTLPPDQIEALLALDPEAFAAEV------- 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 309 vhhtdfvdsaSAMVRHAVALLKPtkvsarqlppsiakvdAKSRALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVN 388
Cdd:PRK09126 248 ----------TARFKGRLGAMRL----------------VSSRHAYPLVAVYAHRFVAKRFALIGDAAVGMHPVTAHGFN 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 389 MGFGDISSLVHHLSTAAFNGKDLGSMSHLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKE 468
Cdd:PRK09126 302 LGLKGQDILARLILAAARRGQDIGAASLLERYERKHRLATRPLYHATNAIAALYTDDRPPARLLRRAVLRAANRFPPLKQ 381


                 ..
gi 568979301 469 QI 470
Cdd:PRK09126 382 AI 383
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 57-467 7.59e-39

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 143.54  E-value: 7.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACALGHdiHFHDkkILLLEAGPkkaleklSETYSNRVSSISPGSTTLLSSFGAWDHICnMRCKAFRRMQVWDSCS-EA 135
Cdd:COG0654   17 ALALALAR--AGIR--VTVVERAP-------PPRPDGRGIALSPRSLELLRRLGLWDRLL-ARGAPIRGIRVRDGSDgRV 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 136 LIMFDRDNLD-DMGYIVENDVIMYALTKQLEAvaDRVKVLYESKAVGYSWPGAFsmadsspwVHITLGDGSTLQTKLLIG 214
Cdd:COG0654   85 LARFDAAETGlPAGLVVPRADLERALLEAARA--LGVELRFGTEVTGLEQDADG--------VTVTLADGRTLRADLVVG 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 215 ADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLseatennvawqrflpsgpiallplsdtlsslvwstshehaaelvsmde 294
Cdd:COG0654  155 ADGARSAVRRLLGIGFTGRDYPQRALWAGVRT------------------------------------------------ 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 295 eEFVDAINSAFWsdvhhtdfvdsasamvrHAVALLkptkvsarqlppsiakvDAKSRALFPLGLGHAAEYVRPRVALIGD 374
Cdd:COG0654  187 -ELRARLAAAGP-----------------RLGELL-----------------ELSPRSAFPLRRRRAERWRRGRVVLLGD 231

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 375 AAHRIHPLAGQGVNMGFGDISSLVHHLStAAFNGKDLGSMshLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRT 454
Cdd:COG0654  232 AAHTMHPLGGQGANLALRDAAALAWKLA-AALRGRDDEAA--LARYERERRPRAARVQRAADALGRLFHPDSPPLRLLRN 308

                        410
                 ....*....|...
gi 568979301 455 WGLQATNAVSPLK 467
Cdd:COG0654  309 AGLRLLDRLPPLK 321
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
197-471 1.00e-38

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 144.66  E-value: 1.00e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 197 VHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVV-ATLHlsEATENNVAWQRFLPSGPIALLPLSDTLS 275
Cdd:PRK07494 144 VTVTLADGTTLSARLVVGADGRNSPVREAAGIGVRTWSYPQKALVlNFTH--SRPHQNVSTEFHTEGGPFTQVPLPGRRS 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 276 SLVWSTSHEHAAELVSMDEEEFvdainsafwsdvhhtdfvdsASAMVRHAVALLKPTKVSARqlppsiakvdaksRALFP 355
Cdd:PRK07494 222 SLVWVVRPAEAERLLALSDAAL--------------------SAAIEERMQSMLGKLTLEPG-------------RQAWP 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 356 LGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVhhlSTAAFNGKDLGSMSHLTGYetDRQRHNTALL--A 433
Cdd:PRK07494 269 LSGQVAHRFAAGRTALVGEAAHVFPPIGAQGLNLGLRDVATLV---EIVEDRPEDPGSAAVLAAY--DRARRPDILSrtA 343

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 568979301 434 ATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKEQIM 471
Cdd:PRK07494 344 SVDLLNRSLLSDFLPVQDLRAAGLHLLYSFGPLRRLFM 381
PRK06996 PRK06996
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;
57-470 8.81e-34

UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase;


Pssm-ID: 235905 [Multi-domain]  Cd Length: 398  Bit Score: 131.35  E-value: 8.81e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  57 AMACALGHDIHFHDKKILLLEAGpkkalEKLSETYSNRVSSISPGSTTLLSSFGAWDhicnMRCKAFRRMQVWDSCSEAL 136
Cdd:PRK06996  25 ALAGWLARRSATRALSIALIDAR-----EPAASANDPRAIALSHGSRVLLETLGAWP----ADATPIEHIHVSQRGHFGR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 137 IMFDRDNLD--DMGYIVENDVIMYALTKQLEAVADRVkvlyeskavgYSWPGAFSMADSSPWVHITLGDGS---TLQTKL 211
Cdd:PRK06996  96 TLIDRDDHDvpALGYVVRYGSLVAALARAVRGTPVRW----------LTSTTAHAPAQDADGVTLALGTPQgarTLRARI 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 212 LIGADGHK-SGVRQAAGIQNVSWKYDQSAVVATLHLSeATENNVAWQRFLPSGPIALLPLSDTLS---SLVWSTSHEHAA 287
Cdd:PRK06996 166 AVQAEGGLfHDQKADAGDSARRRDYGQTAIVGTVTVS-APRPGWAWERFTHEGPLALLPLGGPRQadyALVWCCAPDEAA 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 288 ELVSMDEEEFVDAINSAFwsdvhhtdfvdsASAMVRHavallkptkvsarqlppsiakVDAKSRALFPLGLGHAAEYVRP 367
Cdd:PRK06996 245 RRAALPDDAFLAELGAAF------------GTRMGRF---------------------TRIAGRHAFPLGLNAARTLVNG 291

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 368 RVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMSHltgyetdRQRHNTALLA-ATDLLKRLYSTSA 446
Cdd:PRK06996 292 RIAAVGNAAQTLHPVAGQGLNLGLRDAHTLADALSDHGATPLALATFAA-------RRALDRRVTIgATDLLPRLFTVDS 364

                        410       420
                 ....*....|....*....|....
gi 568979301 447 TPLVLLRTWGLQATNAVSPLKEQI 470
Cdd:PRK06996 365 RPLAHLRGAALTALEFVPPLKHAL 388
PRK06617 PRK06617
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
 94-474 6.69e-29

2-octaprenyl-6-methoxyphenyl hydroxylase; Validated


Pssm-ID: 168629 [Multi-domain]  Cd Length: 374  Bit Score: 117.33  E-value: 6.69e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  94 RVSSISPGSTTLLSSFGAWDHICNMRCKaFRRMQVWDSCSEALIMFDRDNLDDMGYIVENdvimyaltkqleavADRVKV 173
Cdd:PRK06617  45 RTTALTPHSKNFLFSIDIWEELEKFVAE-MQDIYVVDNKASEILDLRNDADAVLGYVVKN--------------SDFKKI 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 174 LYeSKAVGYSWpgaFSMADSSPW--------VHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLH 245
Cdd:PRK06617 110 LL-SKITNNPL---ITLIDNNQYqevishndYSIIKFDDKQIKCNLLIICDGANSKVRSHYFANEIEKPYQTALTFNIKH 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 246 lsEATENNVAWQRFLPSGPIALLPLSDTL-SSLVWSTSHEHAAELVSMDEEEfvdainsafwsdvhhtdfvdsasamVRH 324
Cdd:PRK06617 186 --EKPHENCAMEHFLPLGPFALLPLKDQYaSSVIWSTSSDQAALIVNLPVEE-------------------------VRF 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 325 avallkptkVSARQLPPSIAKVDAKSR-ALFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLST 403
Cdd:PRK06617 239 ---------LTQRNAGNSLGKITIDSEiSSFPLKARIANRYFHNRIVLIADTAHTVHPLAGQGLNQGIKDIEILSMIVSN 309

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568979301 404 aafNGKdlgsmshLTGYETDRQRHNTALLAATDLLKRLYSTSATPLVLLRTWGLQATNAVSPLKEQIMAFA 474
Cdd:PRK06617 310 ---NGT-------LQEYQKLRQEDNFIMYKLTDELNNIFSNYSKNLRCLRQIGFKVINNFKPIKNLITSYA 370
PRK06834 PRK06834
hypothetical protein; Provisional
 197-393 2.86e-10

hypothetical protein; Provisional


Pssm-ID: 235870 [Multi-domain]  Cd Length: 488  Bit Score: 62.34  E-value: 2.86e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 197 VHITLGDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNV--------AWQRFLPSGPIAll 268
Cdd:PRK06834 133 VDVELSDGRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPTTSYLIAEVEMTEEPEWGVhrdalgihAFGRLEDEGPVR-- 210

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 269 plsdtlssLVWSTSHEHAAELVSMDeeEFVDAINSAFWSD--VHHTDFVDSASAMvrhavallkptkvsARQlppsiakv 346
Cdd:PRK06834 211 --------VMVTEKQVGATGEPTLD--DLREALIAVYGTDygIHSPTWISRFTDM--------------ARQ-------- 258

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 568979301 347 daksralfplglghAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGD 393
Cdd:PRK06834 259 --------------AASYRDGRVLLAGDAAHVHSPVGGQGLNTGVQD 291
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 202-435 2.08e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 58.88  E-value: 2.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  202 GDGSTLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLS------EATENNVAWQRFLPSGPIALLPLSDTLS 275
Cdd:pfam01494 143 GEEYTVRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDApdlsdpVERAFVHYLIYAPHSRGFMVGPWRSAGR 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  276 S---LVWSTSHEHAAELVSMDEEEFVDAINSAfwsdvHHTDFVDsasamvrhavallkptkvsarqlppsiAKVDAKSRa 352
Cdd:pfam01494 223 EryyVQVPWDEEVEERPEEFTDEELKQRLRSI-----VGIDLAL---------------------------VEILWKSI- 269

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  353 lFPLGLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLStAAFNGKdlGSMSHLTGYETDRQRHNTALL 432
Cdd:pfam01494 270 -WGVASRVATRYRKGRVFLAGDAAHIHPPTGGQGLNTAIQDAFNLAWKLA-AVLRGQ--AGESLLDTYSAERLPVAWAVV 345


                  ...
gi 568979301  433 AAT 435
Cdd:pfam01494 346 DFA 348
PRK07045 PRK07045
putative monooxygenase; Reviewed
 199-433 6.49e-09

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 57.61  E-value: 6.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 199 ITLGDGSTLQTKLLIGADGHKSGVRQ-AAGIQNVSWKYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSL 277
Cdd:PRK07045 144 VTLSDGERVAPTVLVGADGARSMIRDdVLRMPAERVPYATPMAFGTIALTDSVRECNRLYVDSNQGLAYFYPIGDQATRL 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 278 VWSTSHEHAAELVSMDEEEFVDAINSAFWSDvhhtdfvDSASAMvrhavallkptkvsarqlppsiAKVDAKSR-ALFPL 356
Cdd:PRK07045 224 VVSFPADEMQGYLADTTRTKLLARLNEFVGD-------ESADAM----------------------AAIGAGTAfPLIPL 274

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568979301 357 GLGHAAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLSTAAFNGKDLGSMshLTGYETDRQRHNTALLA 433
Cdd:PRK07045 275 GRMNLDRYHKRNVVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHLSGQIALADA--LERFERIRRPVNEAVIS 349
PRK08244 PRK08244
monooxygenase;
205-473 6.11e-08

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 54.75  E-value: 6.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 205 STLQTKLLIGADGHKSGVRQAAGIQNVSWKYDQSAVVATLHLSEATENNVAwQRFLPSGPIALLPLSDTLSSLVWSTSHE 284
Cdd:PRK08244 144 RTLTSSYVVGADGAGSIVRKQAGIAFPGTDATFTAMLGDVVLKDPPPSSVL-SLCTREGGVMIVPLSGGIYRVLIIDPER 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 285 HAA---ELVSmdEEEFVDAInsafwSDVHHTDF-VDSASAMVRHAVAllkptkvsARQlppsiakvdaksralfplglgh 360
Cdd:PRK08244 223 PQVpkdEPVT--LEELKTSL-----IRICGTDFgLNDPVWMSRFGNA--------TRQ---------------------- 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 361 AAEYVRPRVALIGDAAHrIH-PLAGQGVNMGFGDISSLVHHLStAAFNGKDLGSMshLTGYETDRQRHNTALLAATDLLK 439
Cdd:PRK08244 266 AERYRSGRIFLAGDAAH-IHfPAGGQGLNVGLQDAMNLGWKLA-AAIKGWAPDWL--LDSYHAERHPVGTALLRNTEVQT 341

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 568979301 440 RL--YSTSATPLVLLRTWGLQATNAVSPLKEQIMAF 473
Cdd:PRK08244 342 KLfdFTRPGLALRSMLSDLLGFPEVNRYLAGQISAL 377
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
69-240 1.14e-04

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 43.80  E-value: 1.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301  69 HDKKILLLEAGPkkaleklSETYSNRVSSISPGSTTLLSSFGAWDHICNmrckAFRRMQVWdSCSEALIMFDRDNldDMG 148
Cdd:COG0644   15 AGLSVLLLEKGS-------FPGDKICGGGLLPRALEELEPLGLDEPLER----PVRGARFY-SPGGKSVELPPGR--GGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 149 YIVENDVIMYALTKQleAVADRVKVLYESKAVGYSWPGAfsmadsspWVHITLGDGSTLQTKLLIGADGHKSGVRQAAGI 228
Cdd:COG0644   81 YVVDRARFDRWLAEQ--AEEAGAEVRTGTRVTDVLRDDG--------RVVVRTGDGEEIRADYVVDADGARSLLARKLGL 150

                        170
                 ....*....|..
gi 568979301 229 QNVSWKYDQSAV 240
Cdd:COG0644  151 KRRSDEPQDYAL 162
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
361-455 1.62e-03

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 40.66  E-value: 1.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568979301 361 AAEYVRPRVALIGDAAHRIHPLAGQGVNMGFGDISSLVHHLStAAFNGK---DLgsmshLTGYETDRQRHNTALLAATDL 437
Cdd:PRK06183 280 ADRWRSGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKLA-AVLRGRagdAL-----LDTYEQERRPHARAMIDLAVR 353

                         90
                 ....*....|....*...
gi 568979301 438 LKRLYSTSATPLVLLRTW 455
Cdd:PRK06183 354 LGRVICPTDRLAAALRDA 371
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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