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Conserved domains on  [gi|568972515|ref|XP_006532702|]
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seizure protein 6 isoform X3 [Mus musculus]

Protein Classification

CUB domain-containing protein; beta-2-glycoprotein 1( domain architecture ID 12869276)

CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein| beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 254-364 5.78e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 5.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 254 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 329
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 330 YLPIEgLLSSGRHFFVEFSTDSSGAAAGMALRYEA 364
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 431-540 5.70e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 88.62  E-value: 5.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 431 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSG-----DVLTFYDGDDLTARVLGQYSGPR 504
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 568972515 505 GHFKLFTSMADVTIQFQSDPGTSAlgyqQGFVIHFF 540
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTG----RGFKATYS 112
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 548-604 1.93e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.26  E-value: 1.93e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQ 604
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 548-733 4.32e-14

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 73.15  E-value: 4.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELvhGTVVTYQCYPGYQVVGSSILMCQW----DLSWSEDLPSCQRVtSCHDPGDVEHSRRLIS 623
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 624 SPKFPVGATVQYVCDQGFVLTGSAILTChdrqaGSPKWSDrAPKClleQFKPCHGLSAPENGARSPEKRLHPAGATIHFS 703
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 568972515 704 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 733
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
Sushi pfam00084
Sushi repeat (SCR repeat);
370-427 1.00e-10

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.89  E-value: 1.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515  370 CYEPF-VKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECVDlhDPQWNETEPAC 427
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 82-190 1.93e-07

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 50.10  E-value: 1.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  82 CSWNFSGP-EGSLDSPTAPSSPSDvGLDCFYYISVYPGYGVEIKVENISLQEGET-----ITVEGLGGPDPLPLANQSFL 155
Cdd:cd00041    1 CGGTLTAStSGTISSPNYPNNYPN-NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 156 LRGQVIRSPTHQAALRFQSLPLPAGPGtFHFRYQA 190
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 195-251 2.79e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 2.79e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515 195 CHFPRRPAYGDVTV--TSLHPGGSAHFHCATGYQLKGARFLTCLNATQpfWDSQEPVCI 251
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 254-364 5.78e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 5.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 254 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 329
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 330 YLPIEgLLSSGRHFFVEFSTDSSGAAAGMALRYEA 364
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 431-540 5.70e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 88.62  E-value: 5.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 431 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSG-----DVLTFYDGDDLTARVLGQYSGPR 504
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 568972515 505 GHFKLFTSMADVTIQFQSDPGTSAlgyqQGFVIHFF 540
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTG----RGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 264-362 1.00e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 84.75  E-value: 1.00e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   264 GRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVEYLPIEGLLSS 339
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 568972515   340 GRHFFVEFSTDSSGAAAGMALRY 362
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 440-539 5.96e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 79.74  E-value: 5.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   440 GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSG-----DVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMA 514
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 568972515   515 D-VTIQFQSDPGTSAlgyqQGFVIHF 539
Cdd:smart00042  81 NsLTLTFVSDSSVQK----RGFSARY 102
CUB pfam00431
CUB domain;
254-362 1.08e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 73.48  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  254 CGGVIRNATtGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNvEAPPVYDSYEVE 329
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 568972515  330 YLPiEGLLSSGRHFFVEFSTDSSGAAAGMALRY 362
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB pfam00431
CUB domain;
431-539 1.07e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 70.79  E-value: 1.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  431 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML-----DIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRG 505
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 568972515  506 HFKLFTSMADVTIQFQSDPGTSAlgyqQGFVIHF 539
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASVQK----RGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 548-604 1.93e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.26  E-value: 1.93e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQ 604
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 548-603 2.36e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 67.94  E-value: 2.36e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515   548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 548-733 4.32e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 73.15  E-value: 4.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELvhGTVVTYQCYPGYQVVGSSILMCQW----DLSWSEDLPSCQRVtSCHDPGDVEHSRRLIS 623
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 624 SPKFPVGATVQYVCDQGFVLTGSAILTChdrqaGSPKWSDrAPKClleQFKPCHGLSAPENGARSPEKRLHPAGATIHFS 703
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 568972515 704 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 733
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 676-734 1.48e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 1.48e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515 676 CHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPICR 734
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 609-668 4.63e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 4.63e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKC 668
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE----NGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
548-603 7.25e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 7.25e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515  548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
370-427 1.00e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.89  E-value: 1.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515  370 CYEPF-VKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECVDlhDPQWNETEPAC 427
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 373-428 2.61e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.61e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515 373 PFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECVDlhDPQWNETEPACR 428
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 373-427 1.18e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 1.18e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568972515   373 PFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECvdLHDPQWNETEPAC 427
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITC--LENGTWSPPPPTC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 82-190 1.93e-07

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 50.10  E-value: 1.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  82 CSWNFSGP-EGSLDSPTAPSSPSDvGLDCFYYISVYPGYGVEIKVENISLQEGET-----ITVEGLGGPDPLPLANQSFL 155
Cdd:cd00041    1 CGGTLTAStSGTISSPNYPNNYPN-NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 156 LRGQVIRSPTHQAALRFQSLPLPAGPGtFHFRYQA 190
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
Sushi pfam00084
Sushi repeat (SCR repeat);
609-668 4.68e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.68e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKC 668
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQE----DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 195-251 2.79e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 2.79e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515 195 CHFPRRPAYGDVTV--TSLHPGGSAHFHCATGYQLKGARFLTCLNATQpfWDSQEPVCI 251
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 195-250 3.47e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 3.47e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568972515   195 CHFPRRPAYGDVTVTS--LHPGGSAHFHCATGYQLKGARFLTCLNATQpfWDSQEPVC 250
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 542-603 4.43e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.06  E-value: 4.43e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515 542 VPRNDTCP----ELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 254-364 5.78e-25

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 100.18  E-value: 5.78e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 254 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVE 329
Cdd:cd00041    1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSPncsyDYLEIYDGPSTSS-PLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 330 YLPIEgLLSSGRHFFVEFSTDSSGAAAGMALRYEA 364
Cdd:cd00041   80 TLPPP-IISSGNSLTVRFRSDSSVTGRGFKATYSA 113
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 431-540 5.70e-21

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 88.62  E-value: 5.70e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 431 CSGEITDSA-GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSG-----DVLTFYDGDDLTARVLGQYSGPR 504
Cdd:cd00041    1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 568972515 505 GHFKLFTSMADVTIQFQSDPGTSAlgyqQGFVIHFF 540
Cdd:cd00041   81 LPPPIISSGNSLTVRFRSDSSVTG----RGFKATYS 112
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 264-362 1.00e-19

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 84.75  E-value: 1.00e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   264 GRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNVEApPVYDSYEVEYLPIEGLLSS 339
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASS-PLLGRFCGSEAPPPVISSS 79

                           90       100
                   ....*....|....*....|...
gi 568972515   340 GRHFFVEFSTDSSGAAAGMALRY 362
Cdd:smart00042  80 SNSLTLTFVSDSSVQKRGFSARY 102
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 440-539 5.96e-18

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 79.74  E-value: 5.96e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   440 GVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSG-----DVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMA 514
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEAPPPVISSSS 80

                           90       100
                   ....*....|....*....|....*.
gi 568972515   515 D-VTIQFQSDPGTSAlgyqQGFVIHF 539
Cdd:smart00042  81 NsLTLTFVSDSSVQK----RGFSARY 102
CUB pfam00431
CUB domain;
254-362 1.08e-15

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 73.48  E-value: 1.08e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  254 CGGVIRNATtGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDD----DRLIIRNGNNvEAPPVYDSYEVE 329
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHDecgyDYVEIRDGPS-ASSPLLGRFCGS 78

                          90       100       110
                  ....*....|....*....|....*....|...
gi 568972515  330 YLPiEGLLSSGRHFFVEFSTDSSGAAAGMALRY 362
Cdd:pfam00431  79 GIP-EDIVSSSNQMTIKFVSDASVQKRGFKATY 110
CUB pfam00431
CUB domain;
431-539 1.07e-14

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 70.79  E-value: 1.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  431 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML-----DIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRG 505
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLtfqdfELEDHDECGYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 568972515  506 HFKLFTSMADVTIQFQSDPGTSAlgyqQGFVIHF 539
Cdd:pfam00431  81 PEDIVSSSNQMTIKFVSDASVQK----RGFKATY 110
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 548-604 1.93e-14

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 68.26  E-value: 1.93e-14
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQ 604
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 548-603 2.36e-14

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 67.94  E-value: 2.36e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515   548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 548-733 4.32e-14

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 73.15  E-value: 4.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELvhGTVVTYQCYPGYQVVGSSILMCQW----DLSWSEDLPSCQRVtSCHDPGDVEHSRRLIS 623
Cdd:PHA02927  86 CPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGY 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 624 SPKFPVGATVQYVCDQGFVLTGSAILTChdrqaGSPKWSDrAPKClleQFKPCHGLSAPENGARSPEKRLHPAGATIHFS 703
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLC-----SGGEWSD-PPTC---QIVKCPHPTISNGYLSSGFKRSYSYNDNVDFK 233

                        170       180       190
                 ....*....|....*....|....*....|
gi 568972515 704 CAPGYVLKGQASIKCVPGHPshWSDPPPIC 733
Cdd:PHA02927 234 CKYGYKLSGSSSSTCSPGNT--WQPELPKC 261
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 569-730 1.29e-12

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 68.91  E-value: 1.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 569 GTVVTYQCYPGY--QVVGSSILMCQ---WDLswsedLPSCQRvTSCHDPGDVEHSRRLISSPKFpvGATVQYVCDQGFVL 643
Cdd:PHA02927  47 GDTIEYLCLPGYrkQKMGPIYAKCTgtgWTL-----FNQCIK-RRCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 644 TGSAILTCHDRQAGSPKWSDRAPKCllEQFKpCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGhp 723
Cdd:PHA02927 119 IGESKSYCELGSTGSMVWNPEAPIC--ESVK-CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-- 193


                 ....*..
gi 568972515 724 sHWSDPP 730
Cdd:PHA02927 194 -EWSDPP 199
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 676-734 1.48e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.17  E-value: 1.48e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515 676 CHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPICR 734
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 609-668 4.63e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 58.69  E-value: 4.63e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515   609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKC 668
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLE----NGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
548-603 7.25e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 7.25e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515  548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 609-668 9.27e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 9.27e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKC 668
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTE----NGGWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
370-427 1.00e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.89  E-value: 1.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515  370 CYEPF-VKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECVDlhDPQWNETEPAC 427
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRL-VGSPTITCQE--DGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 676-733 3.86e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 3.86e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568972515   676 CHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPIC 733
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 547-675 7.84e-10

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 61.26  E-value: 7.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 547 TCPELP----EIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDlSWSEdLPSCQRvtSCHDPgdvEHSRRLI 622
Cdd:PHA02954 124 TCPNAEcqplQLEHGSCQPVKEKYSFGEHITINCDVGYEVIGASYISCTAN-SWNV-IPSCQQ--KCDIP---SLSNGLI 196

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568972515 623 SSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagsPKWSDRAPKCLL--EQFKP 675
Cdd:PHA02954 197 SGSTFSIGGVIHLSCKSGFTLTGSPSSTCID-----GKWNPVLPICVRsnEEFDP 246
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 548-669 1.57e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 59.67  E-value: 1.57e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDlSWSeDLPSCQrVTSCHDPGDVEHSRRLISSPKF 627
Cdd:PHA02927 148 CQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG-EWS-DPPTCQ-IVKCPHPTISNGYLSSGFKRSY 224

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 568972515 628 PVGATVQYVCDQGFVLTGSAILTChdrqagSP--KWSDRAPKCL 669
Cdd:PHA02927 225 SYNDNVDFKCKYGYKLSGSSSSTC------SPgnTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 373-428 2.61e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.61e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515 373 PFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECVDlhDPQWNETEPACR 428
Cdd:cd00033    5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTL-VGSSTITCTE--NGGWSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 609-744 5.41e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 58.52  E-value: 5.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTChDRQAGSPKWSDRAPKCLLeqfKPCHGLSAPENGARS 688
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTC-IKDKNNAIWSNKAPFCML---KECNDPPSIINGKIY 97

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515 689 PEKRLHPAGATIHFSC----APGYVLKGQASIKCVpgHPSHWSDPPPICR------AASLDGFYNG 744
Cdd:PHA02639  98 NKREMYKVGDEIYYVCnehkGVQYSLVGNEKITCI--QDKSWKPDPPICKmincrfPALQNGYING 161
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 373-427 1.18e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 1.18e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 568972515   373 PFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLeQGSIIIECvdLHDPQWNETEPAC 427
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTL-IGSSTITC--LENGTWSPPPPTC 56
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 82-190 1.93e-07

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 50.10  E-value: 1.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  82 CSWNFSGP-EGSLDSPTAPSSPSDvGLDCFYYISVYPGYGVEIKVENISLQEGET-----ITVEGLGGPDPLPLANQSFL 155
Cdd:cd00041    1 CGGTLTAStSGTISSPNYPNNYPN-NLNCVWTIEAPPGYRIRLTFEDFDLESSPNcsydyLEIYDGPSTSSPLLGRFCGS 79

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 568972515 156 LRGQVIRSPTHQAALRFQSLPLPAGPGtFHFRYQA 190
Cdd:cd00041   80 TLPPPIISSGNSLTVRFRSDSSVTGRG-FKATYSA 113
Sushi pfam00084
Sushi repeat (SCR repeat);
609-668 4.68e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.49  E-value: 4.68e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515  609 CHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKC 668
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQE----DGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 195-251 2.79e-06

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 45.15  E-value: 2.79e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568972515 195 CHFPRRPAYGDVTV--TSLHPGGSAHFHCATGYQLKGARFLTCLNATQpfWDSQEPVCI 251
Cdd:cd00033    1 CPPPPVPENGTVTGskGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG--WSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 548-733 3.08e-06

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 50.05  E-value: 3.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLS---WSEDLPSCQrVTSCHDPGDVEHSRRLISS 624
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCM-LKECNDPPSIINGKIYNKR 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 625 PKFPVGATVQYVCDQ----GFVLTGSAILTCHDRQAgspkWSDRAPKCLLEQFKpchgLSAPENGARS--PEKRLHPAGA 698
Cdd:PHA02639 101 EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKS----WKPDPPICKMINCR----FPALQNGYINgiPSNKKFYYKT 172

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 568972515 699 TIHFSCAPGYVLKGQASIKCvpGHPSHWSDPPPIC 733
Cdd:PHA02639 173 RVGFSCKSGFDLVGEKYSTC--NINATWFPSIPTC 205
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 195-250 3.47e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 3.47e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 568972515   195 CHFPRRPAYGDVTVTS--LHPGGSAHFHCATGYQLKGARFLTCLNATQpfWDSQEPVC 250
Cdd:smart00032   1 CPPPPDIENGTVTSSSgtYSYGDTVTYSCDPGYTLIGSSTITCLENGT--WSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 548-669 3.21e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 46.52  E-value: 3.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQC----YPGYQVVGSSILMCqWDLSWSEDLPSCqRVTSCHDPGdVEHSRRLIS 623
Cdd:PHA02831  78 CKDPVTILNGYIKNKKDQYSFGDSVTYACkvnkLEKYSIVGNETVKC-INKQWVPKYPVC-KLIRCKYPA-LQNGFLNVF 154

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 568972515 624 SPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAgspkWSDRAPKCL 669
Cdd:PHA02831 155 EKKFYYGDIVNFKCKKGFILLGSSVSTCDINSI----WYPGIPKCV 196
Sushi pfam00084
Sushi repeat (SCR repeat);
676-733 4.15e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.72  E-value: 4.15e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568972515  676 CHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGhpSHWSDPPPIC 733
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 546-668 6.82e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 44.93  E-value: 6.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 546 DTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPG-----YQVVGSSILMCQWDLSWSEDLPSCQrVTSCHDPG-DVEHSR 619
Cdd:PHA02817  22 NKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCK-IIRCRFPAlQNGFVN 100

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 568972515 620 RLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAgspkWSDRAPKC 668
Cdd:PHA02817 101 GIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSS----WIPKVPIC 145
PHA02831 PHA02831
EEV host range protein; Provisional
 542-603 4.43e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 43.06  E-value: 4.43e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568972515 542 VPRNDTCP----ELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSC 603
Cdd:PHA02831 130 VPKYPVCKlircKYPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
PHA02639 PHA02639
EEV host range protein; Provisional
 548-669 1.24e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 41.57  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 548 CPELPEIPNGWKNPSQPELVHGTVVTYQC--YPG--YQVVGSSILMCQWDLSWSEDLPSCQRVtSCHDPG-DVEHSRRLI 622
Cdd:PHA02639  85 CNDPPSIINGKIYNKREMYKVGDEIYYVCneHKGvqYSLVGNEKITCIQDKSWKPDPPICKMI-NCRFPAlQNGYINGIP 163

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 568972515 623 SSPKFPVGATVQYVCDQGFVLTGSAILTCHDrqagSPKWSDRAPKCL 669
Cdd:PHA02639 164 SNKKFYYKTRVGFSCKSGFDLVGEKYSTCNI----NATWFPSIPTCV 206
PHA02831 PHA02831
EEV host range protein; Provisional
 574-723 3.09e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 40.36  E-value: 3.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 574 YQCYPGYQVVgssILMCQwDLSWSEDlPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYVCD----QGFVLTGSAIL 649
Cdd:PHA02831  48 YKCNNNFDKV---FVTCN-NGSWSTK-NMCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACKvnklEKYSIVGNETV 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972515 650 TCHDRQagspkWSDRAPKCLLEQFKpchgLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKC------VPGHP 723
Cdd:PHA02831 123 KCINKQ-----WVPKYPVCKLIRCK----YPALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCdinsiwYPGIP 193
PHA02639 PHA02639
EEV host range protein; Provisional
 551-605 6.62e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 39.65  E-value: 6.62e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568972515 551 LPEIPNGWKN--PSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQR 605
Cdd:PHA02639 151 FPALQNGYINgiPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVR 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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