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Conserved domains on  [gi|569009329|ref|XP_006541574|]
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coiled-coil domain-containing protein 160 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 145-284 2.75e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009329   145 RLHLLNEELGELSLKCREIERDFENAEKELLNFRKEAS-------VKAVNFQEPGTGASKKDRELQALKNDLSEKATNVK 217
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569009329   218 NLTEELQQAKEVMYRLSLENRNLKDAVRKLK-HQTELNTALLREEMKLF-YELEMEKIRLELGAIKNEL 284
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELEsRLEELEEQLETLRSKVAqLELQIASLNNEIERLEARL 409
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 145-284 2.75e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009329   145 RLHLLNEELGELSLKCREIERDFENAEKELLNFRKEAS-------VKAVNFQEPGTGASKKDRELQALKNDLSEKATNVK 217
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569009329   218 NLTEELQQAKEVMYRLSLENRNLKDAVRKLK-HQTELNTALLREEMKLF-YELEMEKIRLELGAIKNEL 284
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELEsRLEELEEQLETLRSKVAqLELQIASLNNEIERLEARL 409
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 145-284 2.75e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 39.65  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009329   145 RLHLLNEELGELSLKCREIERDFENAEKELLNFRKEAS-------VKAVNFQEPGTGASKKDRELQALKNDLSEKATNVK 217
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISrleqqkqILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569009329   218 NLTEELQQAKEVMYRLSLENRNLKDAVRKLK-HQTELNTALLREEMKLF-YELEMEKIRLELGAIKNEL 284
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELEsRLEELEEQLETLRSKVAqLELQIASLNNEIERLEARL 409
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 152-311 8.94e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.73  E-value: 8.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009329   152 ELGELSLKCREIERDFENAEKELLNFRKEASVKAVNFQEPGTGASKKDRELQALKNDLSEKATNVKNLTEELQQAKEVMY 231
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569009329   232 RLSLENRNLKDAVRKL---KHQTELNTALLREEMKLFyELEMEKIRLELGAIKNELRVEKTLRVKNSRALEVLGRHVASV 308
Cdd:TIGR02168  758 ELEAEIEELEERLEEAeeeLAEAEAEIEELEAQIEQL-KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT 836


                   ...
gi 569009329   309 VRS 311
Cdd:TIGR02168  837 ERR 839
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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