|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
133-537 |
5.16e-60 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 203.60 E-value: 5.16e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 133 QARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSS 212
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 213 SDAARRRsvssfpvPQDNVDTHPGSGKEVRV----PATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEK 288
Cdd:COG2319 81 VLSVAFS-------PDGRLLASASADGTVRLwdlaTGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 289 CEfkGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 368
Cdd:COG2319 154 LL--RTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 369 DLRSKVCIKTV-FAGSSCNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVREME-LLGKITALDLNPERTELLSCSRDDL 444
Cdd:COG2319 232 DLATGKLLRTLtGHSGSVRSVAFSpdGRLLASGSADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGKLLASGSDDGT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 445 LKVIDLRTNAIKQTFSAPgfkcGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLsKQHSSSINAVAWSPSGSH 524
Cdd:COG2319 312 VRLWDLATGKLLRTLTGH----TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTL-TGHTGAVTSVAFSPDGRT 386
|
410
....*....|...
gi 578804524 525 VVSVDKGCKAVLW 537
Cdd:COG2319 387 LASGSADGTVRLW 399
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
248-538 |
1.34e-57 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 193.71 E-value: 1.34e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVfgEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWT 327
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 328 VDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTvFAG----------SSCNDIVCteqcvmS 397
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTT-LRGhtdwvnsvafSPDGTFVA------S 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 398 GHFDKKIRFWDIRSESIVREMEL-LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPgfkcgSDW-TRVVF 475
Cdd:cd00200 153 SSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGH-----ENGvNSVAF 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578804524 476 SPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSkQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA 538
Cdd:cd00200 228 SPDGYLLASGSEDGTIRVWDLRTGECVQTLS-GHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
31-146 |
1.22e-26 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 106.17 E-value: 1.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 31 AFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLV 110
Cdd:pfam08614 1 AFLELIDAYNRLLDRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELAELYRSRGELAQRL 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 578804524 111 IDLNNQMQRKDREMQMNEakRRQARLQKELAEAAKE 146
Cdd:pfam08614 81 VDLNEELQELEKKLREDE--RRLAALEAERAQLEEK 114
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
89-494 |
9.80e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 9.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 89 RIKHQEELTE----LHKKRGELAQLVID------------LNNQM--QRKDREMQMNEAKRRQARLQKELAEAAKE--PL 148
Cdd:PLN00181 287 RIEEQELLLEflflIQQRKQEAADKLQDtisllssdidqvVKRQLvlQQKGSDVRSFLASRKRIRQGAETLAAEEEndDN 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 149 PVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNifglsESPLLGHHSSSDAARRRSVSSFPVPQ 228
Cdd:PLN00181 367 SSKLDDTLESTLLESSRLMRNLKKLESVYFATRYRQIKAAAAAEKPLAR-----YYSALSENGRSSEKSSMSNPAKPPDF 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 229 DNVDTHPG--------------SGKEVRVPAtalcvfDAHDGE-------VNAVQFSPGSRLLATGGMDRRVKLWEVF-- 285
Cdd:PLN00181 442 YINDSRQGgwidpfleglckylSFSKLRVKA------DLKQGDllnssnlVCAIGFDRDGEFFATAGVNKKIKIFECEsi 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 286 ---GEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASN-DFASRIWTVDDYRLRHTLTGHSGKVLSAKFL-LDNARIVSGS 360
Cdd:PLN00181 516 ikdGRDIHYPVVELASRSKLSGICWNSYIKSQVASSNfEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSsADPTLLASGS 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 361 HDRTLKLWDLRSKVCIKTVfagSSCNDIVCTE------QCVMSGHFDKKIRFWDIRSESI-VREMELLGKITALDLNPER 433
Cdd:PLN00181 596 DDGSVKLWSINQGVSIGTI---KTKANICCVQfpsesgRSLAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRFVDS 672
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578804524 434 TELLSCSRDDLLKVIDLRTNA--IKQT--FSAPGFKCGSDWTRVVFSpDGsYVAAGSAEGSLYIW 494
Cdd:PLN00181 673 STLVSSSTDNTLKLWDLSMSIsgINETplHSFMGHTNVKNFVGLSVS-DG-YIATGSETNEVFVY 735
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
248-283 |
1.50e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 47.69 E-value: 1.50e-07
10 20 30
....*....|....*....|....*....|....*.
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWE 283
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
248-283 |
5.05e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 46.18 E-value: 5.05e-07
10 20 30
....*....|....*....|....*....|....*.
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWE 283
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
31-146 |
2.26e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 31 AFEEIILQYNKLLEKSDLHSVLAQKLQAEKhdvPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELaqlv 110
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELL---GELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL---- 458
|
90 100 110
....*....|....*....|....*....|....*.
gi 578804524 111 idlNNQMQRKDREMQMNEAKRRQARLQKELAEAAKE 146
Cdd:COG4717 459 ---EAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
133-537 |
5.16e-60 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 203.60 E-value: 5.16e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 133 QARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSS 212
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 213 SDAARRRsvssfpvPQDNVDTHPGSGKEVRV----PATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEK 288
Cdd:COG2319 81 VLSVAFS-------PDGRLLASASADGTVRLwdlaTGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 289 CEfkGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLW 368
Cdd:COG2319 154 LL--RTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLW 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 369 DLRSKVCIKTV-FAGSSCNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVREME-LLGKITALDLNPERTELLSCSRDDL 444
Cdd:COG2319 232 DLATGKLLRTLtGHSGSVRSVAFSpdGRLLASGSADGTVRLWDLATGELLRTLTgHSGGVNSVAFSPDGKLLASGSDDGT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 445 LKVIDLRTNAIKQTFSAPgfkcGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLsKQHSSSINAVAWSPSGSH 524
Cdd:COG2319 312 VRLWDLATGKLLRTLTGH----TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTL-TGHTGAVTSVAFSPDGRT 386
|
410
....*....|...
gi 578804524 525 VVSVDKGCKAVLW 537
Cdd:COG2319 387 LASGSADGTVRLW 399
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
248-538 |
1.34e-57 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 193.71 E-value: 1.34e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVfgEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWT 327
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 328 VDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTvFAG----------SSCNDIVCteqcvmS 397
Cdd:cd00200 80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTT-LRGhtdwvnsvafSPDGTFVA------S 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 398 GHFDKKIRFWDIRSESIVREMEL-LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPgfkcgSDW-TRVVF 475
Cdd:cd00200 153 SSQDGTIKLWDLRTGKCVATLTGhTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGH-----ENGvNSVAF 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578804524 476 SPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSkQHSSSINAVAWSPSGSHVVSVDKGCKAVLWA 538
Cdd:cd00200 228 SPDGYLLASGSEDGTIRVWDLRTGECVQTLS-GHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
236-496 |
3.85e-48 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 172.02 E-value: 3.85e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 236 GSGKEVRV----PATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFkgSLSGSNAGITSIEFDSAG 311
Cdd:COG2319 139 SADGTVRLwdlaTGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLR--TLTGHTGAVRSVAFSPDG 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 312 SYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSC-NDIVC 390
Cdd:COG2319 217 KLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGvNSVAF 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 391 T--EQCVMSGHFDKKIRFWDIRSESIVREME-LLGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPgfkcg 467
Cdd:COG2319 297 SpdGKLLASGSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGH----- 371
|
250 260 270
....*....|....*....|....*....|
gi 578804524 468 SDW-TRVVFSPDGSYVAAGSAEGSLYIWSV 496
Cdd:COG2319 372 TGAvTSVAFSPDGRTLASGSADGTVRLWDL 401
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
333-537 |
1.16e-34 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 132.07 E-value: 1.16e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 333 LRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTV----FAGSSCNDIVCTEQCVmSGHFDKKIRFWD 408
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLkghtGPVRDVAASADGTYLA-SGSSDKTIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 409 IRSESIVREMEL-LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPgfkcgSDWTR-VVFSPDGSYVAAGS 486
Cdd:cd00200 80 LETGECVRTLTGhTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGH-----TDWVNsVAFSPDGTFVASSS 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 578804524 487 AEGSLYIWSVLTGKVEKVLsKQHSSSINAVAWSPSGSHVV--SVDKGCKavLW 537
Cdd:cd00200 155 QDGTIKLWDLRTGKCVATL-TGHTGEVNSVAFSPDGEKLLssSSDGTIK--LW 204
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
31-146 |
1.22e-26 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 106.17 E-value: 1.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 31 AFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELAQLV 110
Cdd:pfam08614 1 AFLELIDAYNRLLDRTALLEAENAKLQSEPESVLPSTSSSKLSKASPQSASIQSLEQLLAQLREELAELYRSRGELAQRL 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 578804524 111 IDLNNQMQRKDREMQMNEakRRQARLQKELAEAAKE 146
Cdd:pfam08614 81 VDLNEELQELEKKLREDE--RRLAALEAERAQLEEK 114
|
|
| PLN00181 |
PLN00181 |
protein SPA1-RELATED; Provisional |
89-494 |
9.80e-08 |
|
protein SPA1-RELATED; Provisional
Pssm-ID: 177776 [Multi-domain] Cd Length: 793 Bit Score: 55.09 E-value: 9.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 89 RIKHQEELTE----LHKKRGELAQLVID------------LNNQM--QRKDREMQMNEAKRRQARLQKELAEAAKE--PL 148
Cdd:PLN00181 287 RIEEQELLLEflflIQQRKQEAADKLQDtisllssdidqvVKRQLvlQQKGSDVRSFLASRKRIRQGAETLAAEEEndDN 366
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 149 PVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNifglsESPLLGHHSSSDAARRRSVSSFPVPQ 228
Cdd:PLN00181 367 SSKLDDTLESTLLESSRLMRNLKKLESVYFATRYRQIKAAAAAEKPLAR-----YYSALSENGRSSEKSSMSNPAKPPDF 441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 229 DNVDTHPG--------------SGKEVRVPAtalcvfDAHDGE-------VNAVQFSPGSRLLATGGMDRRVKLWEVF-- 285
Cdd:PLN00181 442 YINDSRQGgwidpfleglckylSFSKLRVKA------DLKQGDllnssnlVCAIGFDRDGEFFATAGVNKKIKIFECEsi 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 286 ---GEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASN-DFASRIWTVDDYRLRHTLTGHSGKVLSAKFL-LDNARIVSGS 360
Cdd:PLN00181 516 ikdGRDIHYPVVELASRSKLSGICWNSYIKSQVASSNfEGVVQVWDVARSQLVTEMKEHEKRVWSIDYSsADPTLLASGS 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 361 HDRTLKLWDLRSKVCIKTVfagSSCNDIVCTE------QCVMSGHFDKKIRFWDIRSESI-VREMELLGKITALDLNPER 433
Cdd:PLN00181 596 DDGSVKLWSINQGVSIGTI---KTKANICCVQfpsesgRSLAFGSADHKVYYYDLRNPKLpLCTMIGHSKTVSYVRFVDS 672
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578804524 434 TELLSCSRDDLLKVIDLRTNA--IKQT--FSAPGFKCGSDWTRVVFSpDGsYVAAGSAEGSLYIW 494
Cdd:PLN00181 673 STLVSSSTDNTLKLWDLSMSIsgINETplHSFMGHTNVKNFVGLSVS-DG-YIATGSETNEVFVY 735
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
248-283 |
1.50e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 47.69 E-value: 1.50e-07
10 20 30
....*....|....*....|....*....|....*.
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWE 283
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
332-369 |
3.46e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.54 E-value: 3.46e-07
10 20 30
....*....|....*....|....*....|....*...
gi 578804524 332 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 369
Cdd:smart00320 3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
248-283 |
5.05e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 46.18 E-value: 5.05e-07
10 20 30
....*....|....*....|....*....|....*.
gi 578804524 248 LCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWE 283
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
332-369 |
8.91e-07 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 45.41 E-value: 8.91e-07
10 20 30
....*....|....*....|....*....|....*...
gi 578804524 332 RLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWD 369
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
291-499 |
3.90e-06 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 48.15 E-value: 3.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 291 FKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARI-VSGSHDRTLKLWD 369
Cdd:COG3391 17 ALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLyVANSGSGRVSVID 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 370 LRSKVCIKTVFAGSSCNDIVCTE---QCVMSGHFDKKIRFWDIRSESIVREMELLGKITALDLNPERTELLSCSRDD--- 443
Cdd:COG3391 97 LATGKVVATIPVGGGPRGLAVDPdggRLYVADSGNGRVSVIDTATGKVVATIPVGAGPHGIAVDPDGKRLYVANSGSntv 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578804524 444 --LLKVIDLRTNAIKQTFSApgfkcGSDWTRVVFSPDGS--YVA------AGSAEGSLYIWSVLTG 499
Cdd:COG3391 177 svIVSVIDTATGKVVATIPV-----GGGPVGVAVSPDGRrlYVAnrgsntSNGGSNTVSVIDLATL 237
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
447-526 |
3.67e-05 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 44.28 E-value: 3.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 447 VIDLRTNAIKQTFSAPGFKCGSDWtrvvfSPDGSYVAAGSAEGS---LYIWSVLTGKVEKVLSKQHSSSinAVAWSPSGS 523
Cdd:COG0823 15 VVDLDGGEPRRLTNSPGIDTSPAW-----SPDGRRIAFTSDRGGgpqIYVVDADGGEPRRLTFGGGYNA--SPSWSPDGK 87
|
...
gi 578804524 524 HVV 526
Cdd:COG0823 88 RLA 90
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
474-522 |
2.89e-04 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 43.87 E-value: 2.89e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 578804524 474 VFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSPSG 522
Cdd:COG4946 395 VWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDTDGYGDGISDLAWSPDS 443
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
447-537 |
3.79e-04 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 41.20 E-value: 3.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 447 VIDLRTNAIKQ-TFSapgfkcGSDWTRVVFSPDGSYVA-AGSAEGSLYIWSV-LTGKVEKVLSKqhssSINAVAWSPSGS 523
Cdd:COG0823 59 VVDADGGEPRRlTFG------GGYNASPSWSPDGKRLAfVSRSDGRFDIYVLdLDGGAPRRLTD----GPGSPSWSPDGR 128
|
90
....*....|....*
gi 578804524 524 HVV-SVDKGCKAVLW 537
Cdd:COG0823 129 RIVfSSDRGGRPDLY 143
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
498-537 |
4.58e-04 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 37.68 E-value: 4.58e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 578804524 498 TGKVEKVLsKQHSSSINAVAWSPSGSHVVSVDKGCKAVLW 537
Cdd:smart00320 1 SGELLKTL-KGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
31-146 |
2.26e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 31 AFEEIILQYNKLLEKSDLHSVLAQKLQAEKhdvPNRHEISPGHDGTWNDNQLQEMAQLRIKHQEELTELHKKRGELaqlv 110
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELL---GELEELLEALDEEELEEELEELEEELEELEEELEELREELAEL---- 458
|
90 100 110
....*....|....*....|....*....|....*.
gi 578804524 111 idlNNQMQRKDREMQMNEAKRRQARLQKELAEAAKE 146
Cdd:COG4717 459 ---EAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
473-537 |
2.63e-03 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 40.79 E-value: 2.63e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578804524 473 VVFSPDGSYVAAGS-AEGS--LYIWSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKavLW 537
Cdd:COG4946 348 PAWSPDGKSIAYFSdASGEyeLYIAPADGSGEPKQLTLGDLGRVFNPVWSPDGKKIAFTDNRGR--LW 413
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
84-146 |
2.64e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 40.69 E-value: 2.64e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578804524 84 EMAQLRIKHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQM-NEAKRRQARLQKELAEAAKE 146
Cdd:COG1196 268 ELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERrRELEERLEELEEELAELEEE 331
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
421-524 |
3.67e-03 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 40.41 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 421 LGKITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDwtrVVFSPDGSYVA----AGSAEGSLYIWSV 496
Cdd:COG4946 388 LGRVFNPVWSPDGKKIAFTDNRGRLWVVDLASGKVRKVDTDGYGDGISD---LAWSPDSKWLAyskpGPNQLSQIFLYDV 464
|
90 100
....*....|....*....|....*...
gi 578804524 497 LTGKVEKVLSKQHSSSinAVAWSPSGSH 524
Cdd:COG4946 465 ETGKTVQLTDGRYDDG--SPAFSPDGKY 490
|
|
| Ge1_WD40 |
pfam16529 |
WD40 region of Ge1, enhancer of mRNA-decapping protein; Ge1_WD40 is the N-terminal region of ... |
298-379 |
4.68e-03 |
|
WD40 region of Ge1, enhancer of mRNA-decapping protein; Ge1_WD40 is the N-terminal region of Ge-1 or enhancer of mRNA-decapping proteins. WD40-repeat regions are involved in protein-protein interactions.
Pssm-ID: 465162 [Multi-domain] Cd Length: 328 Bit Score: 39.36 E-value: 4.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578804524 298 SNAGITSIEFDSAGSYLLAASNDFASRIWTV-----DDYRLRHTLTGHSGKVLSAKFLLDNAR----------IVSGS-H 361
Cdd:pfam16529 185 EHSLLVDAAFSPDGTALATASLDGEVKFFQIylfdnRNPRCLHEWKPHDGKPLSSLFFLDNHKkppevqfwrfAITGAdN 264
|
90
....*....|....*...
gi 578804524 362 DRTLKLWDLRSKVCIKTV 379
Cdd:pfam16529 265 NSELKLWSCESWTCLQTI 282
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
471-495 |
9.61e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 34.21 E-value: 9.61e-03
|
| |
