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Conserved domains on  [gi|578817106|ref|XP_006717038|]
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protein shortage in chiasmata 1 ortholog isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF5587 pfam17825
Family of unknown function (DUF5587); This is a family of unknown function found in chordata.
 65-1473 0e+00

Family of unknown function (DUF5587); This is a family of unknown function found in chordata.


:

Pssm-ID: 465523  Cd Length: 1442  Bit Score: 2689.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106    65 MTDTSVLDQWKASFFVEDFLEKKTITRMVTQINCEFEEVVPSSNPDSQIEVEEVSLYTHMDYNEVFTPVSCLEKCSALQN 144
Cdd:pfam17825    1 MTDSSVLDQWKASFFVEDFLEKKTVTGMMTQINGEFEEIVPSSNPNSPIEVEEASLYTHKDYNEVFTPVKCSEKCPALQA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   145 QNQDLFIDDKGILFVSS----RKHLPTLPTLLSRLKLFLVKDPLLDFKGQIFTEANFSRECFSLQETLEAFVKEDFCMDK 220
Cdd:pfam17825   81 QNQDLFIDDEEIIFVNNlatyKSHLPTLNTLLSRLKLFLIKDPLLDFKEQIFTEANFFREYFSFQEDLEPFVKEDFYMDK 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   221 VNFCQEKLEdticlNEPSSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEIINYVDEKEKLFERDLTNKHGIeDIGD 300
Cdd:pfam17825  161 ENFCQEKLE-----NETPSFLSECEFLISTSLKQEIDIPSPSELKESLNLVPEIINYVDENEKLFKRDLTTKHGI-DIED 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   301 IKFSSTEILTIQSQSEPEeCSKPGELEMPLTPLFLTCQHSSVNSLRTELQTFPLSPVCKINLLTAEESANEYYMMWQLER 380
Cdd:pfam17825  235 IKCSSTEILAIQSQCEPE-CSEPGELEMPLTPLHLTNQHSSVNSLCTGLQTFPFSPVCKINLLTAEESANKYCMVWQLES 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   381 CRSPLNPFLLTVPRIQEPHSQYSVTDLKKIFSVKEESLVINLEKAEWWKQAGLNLKMMETLEHLNTYLCHDNLSSNDTKI 460
Cdd:pfam17825  314 CRSSLNSFLLTVPRTQEPNSQYSVTDLKKIFSIKEESLVINPVKAEWWKQAGLNLIMTETLEHLNTYLCHDDLSSDDTKM 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   461 EIFLPTKVLQLESCLEHKSHSSPIALIDEKSTNAHLSLPQKSPSLAKEVPDLCFSDDYFSDKGAAKEEKPKNDQEPVNRI 540
Cdd:pfam17825  394 EIFLPTKVLQLESWLEHKSCSSPIVLINEKSTNDHLLLPQKSPSPAKEVPDLCFSDEYISVKKPKKEEKPKNDQEPVARI 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   541 IQKKENNDHFELDCTGPSIKSPSSSIIKKASFEHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTNSDEKHDKEACSLTL 620
Cdd:pfam17825  474 IQKKENNDCLELDCTVPSIESSSSSKIEKASFKHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTDSDEKNDKEEYSLTL 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   621 QEESPIVHINKTLEEINQERGTDSVIEIQASDSQCQAFCLLEAAASPILKNLVSLCTLPTANWKFATVIFDQTRFLLKEQ 700
Cdd:pfam17825  554 QEESPVVSTNKTLEKINQERRADNVIEIQASDSQCQAYCLLEAAATPILKKLVCLCTLPAANWKFATVIFDQTRFFLKEQ 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   701 EKVVSDAVRQ-----------------------------------GYLSKAKDIYNSILGPYLGDIWRQLEIVQFIRGKK 745
Cdd:pfam17825  634 EKVISDAIHQgtnderemtfkhaallhllvtirdvlltcsldtalGYLSNAKDIYKSILGSYLDDIWRQLEIVQFIREKN 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   746 PETNYKIQELQCQILSWMQSQQQIKVLIIIRMDSDGEKHFLIKILNKIEGLTLTVLHSNERKDFLESEGVLRGTSSCVVV 825
Cdd:pfam17825  714 PETNYKIQELQCQILSWMQSEQQIKVLIIIRMDSDGEKHLLIKILNKIEGLTLTVLHSNKRKDFLESEGVLNGTSSCVVV 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   826 HNQYIGADFPWSNFSFVVEYNYVEDSCWTKHCKELNIPYMAFKVILPDTVLERSTLLDRFGGFLLEIQIPYVFFASEGLL 905
Cdd:pfam17825  794 HNQYIGADFPWSNFSFVVEYNYVENSCWTKHCKKLNIPYMAFKVILPDTVLKRSTLLDRFGGFLLEIQIPYVFFASEGLL 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   906 NTPDILQLLESNYNISLVERGCSESLKLFGSSECYVVVTIDEHTAIILQDLEELNYEKASDNIIMRLMALSLQYRYCWII 985
Cdd:pfam17825  874 NTPEILQLLESNYNITLVERCCSESLKLFGGTECYVVVTIDEHTAIILQDLEELNCEKASDNIIMRLMALSFQYSYCWII 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   986 LYTKETLNSEYLLTEKTLHHLALIYAALVSFGLNSEELDVKLIIAPGVEATALIIRQIADHSLMTSKRDPHEWLDKSWLK 1065
Cdd:pfam17825  954 LYTKETLNSEYHLTEKTLHHLALIYAALVSFGLKSEELDVKLIIAPGVEETALIIRQIADHNLMTSKRDPHEWLDKSWLE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1066 VSPSEEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKIGSSSITKSPQISSP 1145
Cdd:pfam17825 1034 VSPSKEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKISSSSITKSPQISSP 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1146 QENRNQISTLSSQSSASDLDSVIQEHNEYYQYLGLGETVQEDKTTILNDNSSIMELKEISSFLPPVTSYNQTSYWKDSSC 1225
Cdd:pfam17825 1114 QENGNQTSTFISQSSASGSDSVIQEHNEYYQYSDLGETVQEDTNTTSNDNSSLMELREMPCVLPPVTSYSQTSYWKDSSC 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1226 KSNIGQNTPFLINIESRRPAYNSFLNHSDSESDVFSLGLTQMNCETIKSPTDTQKRVSvvPRFINSQKRRTHEAKGFINK 1305
Cdd:pfam17825 1194 NPNIVQNNPFLINIESRKVAGNSFLNQNDSESDVFSLGLTQMNCETIISPIDTQRRVA--PNFINYQKKGTHEAKGPINK 1271

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1306 DVSDPIFSLEGTQSPLHWNFKKNIWEQENHPFNLQYGAQQTACNKLYSQKGNLFTDQQKCLSDESEGLTCESSKD---ET 1382
Cdd:pfam17825 1272 EVSAPVFSLEGSQSPLHWNFKKNVWEQQNHSFNLQYGAEQTTCDKWYSQKDNLFTNQQKCLSDELEGLTYESSNAgtkET 1351

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1383 FWRELPSVPSLDLFRASDSNANQKEFNSLYFYQRAGKSLGQKRHHESSFNSGDKESLTGFMCSQLPQFKKRRLAYEKVPG 1462
Cdd:pfam17825 1352 FWRELPSVPSLDLFCASDSNVNQKEFNSLYFYQRAGKCLGQKRHLESSSNSGDKKSLTDLMCSQLPQFKKRRLVYEKVPG 1431

                         1450
                   ....*....|.
gi 578817106  1463 RVDGQTRLRFF 1473
Cdd:pfam17825 1432 RADGQTRLRFF 1442
 
Name Accession Description Interval E-value
DUF5587 pfam17825
Family of unknown function (DUF5587); This is a family of unknown function found in chordata.
 65-1473 0e+00

Family of unknown function (DUF5587); This is a family of unknown function found in chordata.


Pssm-ID: 465523  Cd Length: 1442  Bit Score: 2689.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106    65 MTDTSVLDQWKASFFVEDFLEKKTITRMVTQINCEFEEVVPSSNPDSQIEVEEVSLYTHMDYNEVFTPVSCLEKCSALQN 144
Cdd:pfam17825    1 MTDSSVLDQWKASFFVEDFLEKKTVTGMMTQINGEFEEIVPSSNPNSPIEVEEASLYTHKDYNEVFTPVKCSEKCPALQA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   145 QNQDLFIDDKGILFVSS----RKHLPTLPTLLSRLKLFLVKDPLLDFKGQIFTEANFSRECFSLQETLEAFVKEDFCMDK 220
Cdd:pfam17825   81 QNQDLFIDDEEIIFVNNlatyKSHLPTLNTLLSRLKLFLIKDPLLDFKEQIFTEANFFREYFSFQEDLEPFVKEDFYMDK 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   221 VNFCQEKLEdticlNEPSSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEIINYVDEKEKLFERDLTNKHGIeDIGD 300
Cdd:pfam17825  161 ENFCQEKLE-----NETPSFLSECEFLISTSLKQEIDIPSPSELKESLNLVPEIINYVDENEKLFKRDLTTKHGI-DIED 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   301 IKFSSTEILTIQSQSEPEeCSKPGELEMPLTPLFLTCQHSSVNSLRTELQTFPLSPVCKINLLTAEESANEYYMMWQLER 380
Cdd:pfam17825  235 IKCSSTEILAIQSQCEPE-CSEPGELEMPLTPLHLTNQHSSVNSLCTGLQTFPFSPVCKINLLTAEESANKYCMVWQLES 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   381 CRSPLNPFLLTVPRIQEPHSQYSVTDLKKIFSVKEESLVINLEKAEWWKQAGLNLKMMETLEHLNTYLCHDNLSSNDTKI 460
Cdd:pfam17825  314 CRSSLNSFLLTVPRTQEPNSQYSVTDLKKIFSIKEESLVINPVKAEWWKQAGLNLIMTETLEHLNTYLCHDDLSSDDTKM 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   461 EIFLPTKVLQLESCLEHKSHSSPIALIDEKSTNAHLSLPQKSPSLAKEVPDLCFSDDYFSDKGAAKEEKPKNDQEPVNRI 540
Cdd:pfam17825  394 EIFLPTKVLQLESWLEHKSCSSPIVLINEKSTNDHLLLPQKSPSPAKEVPDLCFSDEYISVKKPKKEEKPKNDQEPVARI 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   541 IQKKENNDHFELDCTGPSIKSPSSSIIKKASFEHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTNSDEKHDKEACSLTL 620
Cdd:pfam17825  474 IQKKENNDCLELDCTVPSIESSSSSKIEKASFKHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTDSDEKNDKEEYSLTL 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   621 QEESPIVHINKTLEEINQERGTDSVIEIQASDSQCQAFCLLEAAASPILKNLVSLCTLPTANWKFATVIFDQTRFLLKEQ 700
Cdd:pfam17825  554 QEESPVVSTNKTLEKINQERRADNVIEIQASDSQCQAYCLLEAAATPILKKLVCLCTLPAANWKFATVIFDQTRFFLKEQ 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   701 EKVVSDAVRQ-----------------------------------GYLSKAKDIYNSILGPYLGDIWRQLEIVQFIRGKK 745
Cdd:pfam17825  634 EKVISDAIHQgtnderemtfkhaallhllvtirdvlltcsldtalGYLSNAKDIYKSILGSYLDDIWRQLEIVQFIREKN 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   746 PETNYKIQELQCQILSWMQSQQQIKVLIIIRMDSDGEKHFLIKILNKIEGLTLTVLHSNERKDFLESEGVLRGTSSCVVV 825
Cdd:pfam17825  714 PETNYKIQELQCQILSWMQSEQQIKVLIIIRMDSDGEKHLLIKILNKIEGLTLTVLHSNKRKDFLESEGVLNGTSSCVVV 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   826 HNQYIGADFPWSNFSFVVEYNYVEDSCWTKHCKELNIPYMAFKVILPDTVLERSTLLDRFGGFLLEIQIPYVFFASEGLL 905
Cdd:pfam17825  794 HNQYIGADFPWSNFSFVVEYNYVENSCWTKHCKKLNIPYMAFKVILPDTVLKRSTLLDRFGGFLLEIQIPYVFFASEGLL 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   906 NTPDILQLLESNYNISLVERGCSESLKLFGSSECYVVVTIDEHTAIILQDLEELNYEKASDNIIMRLMALSLQYRYCWII 985
Cdd:pfam17825  874 NTPEILQLLESNYNITLVERCCSESLKLFGGTECYVVVTIDEHTAIILQDLEELNCEKASDNIIMRLMALSFQYSYCWII 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   986 LYTKETLNSEYLLTEKTLHHLALIYAALVSFGLNSEELDVKLIIAPGVEATALIIRQIADHSLMTSKRDPHEWLDKSWLK 1065
Cdd:pfam17825  954 LYTKETLNSEYHLTEKTLHHLALIYAALVSFGLKSEELDVKLIIAPGVEETALIIRQIADHNLMTSKRDPHEWLDKSWLE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1066 VSPSEEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKIGSSSITKSPQISSP 1145
Cdd:pfam17825 1034 VSPSKEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKISSSSITKSPQISSP 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1146 QENRNQISTLSSQSSASDLDSVIQEHNEYYQYLGLGETVQEDKTTILNDNSSIMELKEISSFLPPVTSYNQTSYWKDSSC 1225
Cdd:pfam17825 1114 QENGNQTSTFISQSSASGSDSVIQEHNEYYQYSDLGETVQEDTNTTSNDNSSLMELREMPCVLPPVTSYSQTSYWKDSSC 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1226 KSNIGQNTPFLINIESRRPAYNSFLNHSDSESDVFSLGLTQMNCETIKSPTDTQKRVSvvPRFINSQKRRTHEAKGFINK 1305
Cdd:pfam17825 1194 NPNIVQNNPFLINIESRKVAGNSFLNQNDSESDVFSLGLTQMNCETIISPIDTQRRVA--PNFINYQKKGTHEAKGPINK 1271

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1306 DVSDPIFSLEGTQSPLHWNFKKNIWEQENHPFNLQYGAQQTACNKLYSQKGNLFTDQQKCLSDESEGLTCESSKD---ET 1382
Cdd:pfam17825 1272 EVSAPVFSLEGSQSPLHWNFKKNVWEQQNHSFNLQYGAEQTTCDKWYSQKDNLFTNQQKCLSDELEGLTYESSNAgtkET 1351

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1383 FWRELPSVPSLDLFRASDSNANQKEFNSLYFYQRAGKSLGQKRHHESSFNSGDKESLTGFMCSQLPQFKKRRLAYEKVPG 1462
Cdd:pfam17825 1352 FWRELPSVPSLDLFCASDSNVNQKEFNSLYFYQRAGKCLGQKRHLESSSNSGDKKSLTDLMCSQLPQFKKRRLVYEKVPG 1431

                         1450
                   ....*....|.
gi 578817106  1463 RVDGQTRLRFF 1473
Cdd:pfam17825 1432 RADGQTRLRFF 1442
 
Name Accession Description Interval E-value
DUF5587 pfam17825
Family of unknown function (DUF5587); This is a family of unknown function found in chordata.
 65-1473 0e+00

Family of unknown function (DUF5587); This is a family of unknown function found in chordata.


Pssm-ID: 465523  Cd Length: 1442  Bit Score: 2689.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106    65 MTDTSVLDQWKASFFVEDFLEKKTITRMVTQINCEFEEVVPSSNPDSQIEVEEVSLYTHMDYNEVFTPVSCLEKCSALQN 144
Cdd:pfam17825    1 MTDSSVLDQWKASFFVEDFLEKKTVTGMMTQINGEFEEIVPSSNPNSPIEVEEASLYTHKDYNEVFTPVKCSEKCPALQA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   145 QNQDLFIDDKGILFVSS----RKHLPTLPTLLSRLKLFLVKDPLLDFKGQIFTEANFSRECFSLQETLEAFVKEDFCMDK 220
Cdd:pfam17825   81 QNQDLFIDDEEIIFVNNlatyKSHLPTLNTLLSRLKLFLIKDPLLDFKEQIFTEANFFREYFSFQEDLEPFVKEDFYMDK 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   221 VNFCQEKLEdticlNEPSSFLIEYEFLIPPSLKPEIDIPSLSELKELLNPVPEIINYVDEKEKLFERDLTNKHGIeDIGD 300
Cdd:pfam17825  161 ENFCQEKLE-----NETPSFLSECEFLISTSLKQEIDIPSPSELKESLNLVPEIINYVDENEKLFKRDLTTKHGI-DIED 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   301 IKFSSTEILTIQSQSEPEeCSKPGELEMPLTPLFLTCQHSSVNSLRTELQTFPLSPVCKINLLTAEESANEYYMMWQLER 380
Cdd:pfam17825  235 IKCSSTEILAIQSQCEPE-CSEPGELEMPLTPLHLTNQHSSVNSLCTGLQTFPFSPVCKINLLTAEESANKYCMVWQLES 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   381 CRSPLNPFLLTVPRIQEPHSQYSVTDLKKIFSVKEESLVINLEKAEWWKQAGLNLKMMETLEHLNTYLCHDNLSSNDTKI 460
Cdd:pfam17825  314 CRSSLNSFLLTVPRTQEPNSQYSVTDLKKIFSIKEESLVINPVKAEWWKQAGLNLIMTETLEHLNTYLCHDDLSSDDTKM 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   461 EIFLPTKVLQLESCLEHKSHSSPIALIDEKSTNAHLSLPQKSPSLAKEVPDLCFSDDYFSDKGAAKEEKPKNDQEPVNRI 540
Cdd:pfam17825  394 EIFLPTKVLQLESWLEHKSCSSPIVLINEKSTNDHLLLPQKSPSPAKEVPDLCFSDEYISVKKPKKEEKPKNDQEPVARI 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   541 IQKKENNDHFELDCTGPSIKSPSSSIIKKASFEHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTNSDEKHDKEACSLTL 620
Cdd:pfam17825  474 IQKKENNDCLELDCTVPSIESSSSSKIEKASFKHGKKQENDLDLLSDFIMLRNKYKTCTSKTEVTDSDEKNDKEEYSLTL 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   621 QEESPIVHINKTLEEINQERGTDSVIEIQASDSQCQAFCLLEAAASPILKNLVSLCTLPTANWKFATVIFDQTRFLLKEQ 700
Cdd:pfam17825  554 QEESPVVSTNKTLEKINQERRADNVIEIQASDSQCQAYCLLEAAATPILKKLVCLCTLPAANWKFATVIFDQTRFFLKEQ 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   701 EKVVSDAVRQ-----------------------------------GYLSKAKDIYNSILGPYLGDIWRQLEIVQFIRGKK 745
Cdd:pfam17825  634 EKVISDAIHQgtnderemtfkhaallhllvtirdvlltcsldtalGYLSNAKDIYKSILGSYLDDIWRQLEIVQFIREKN 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   746 PETNYKIQELQCQILSWMQSQQQIKVLIIIRMDSDGEKHFLIKILNKIEGLTLTVLHSNERKDFLESEGVLRGTSSCVVV 825
Cdd:pfam17825  714 PETNYKIQELQCQILSWMQSEQQIKVLIIIRMDSDGEKHLLIKILNKIEGLTLTVLHSNKRKDFLESEGVLNGTSSCVVV 793

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   826 HNQYIGADFPWSNFSFVVEYNYVEDSCWTKHCKELNIPYMAFKVILPDTVLERSTLLDRFGGFLLEIQIPYVFFASEGLL 905
Cdd:pfam17825  794 HNQYIGADFPWSNFSFVVEYNYVENSCWTKHCKKLNIPYMAFKVILPDTVLKRSTLLDRFGGFLLEIQIPYVFFASEGLL 873

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   906 NTPDILQLLESNYNISLVERGCSESLKLFGSSECYVVVTIDEHTAIILQDLEELNYEKASDNIIMRLMALSLQYRYCWII 985
Cdd:pfam17825  874 NTPEILQLLESNYNITLVERCCSESLKLFGGTECYVVVTIDEHTAIILQDLEELNCEKASDNIIMRLMALSFQYSYCWII 953

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106   986 LYTKETLNSEYLLTEKTLHHLALIYAALVSFGLNSEELDVKLIIAPGVEATALIIRQIADHSLMTSKRDPHEWLDKSWLK 1065
Cdd:pfam17825  954 LYTKETLNSEYHLTEKTLHHLALIYAALVSFGLKSEELDVKLIIAPGVEETALIIRQIADHNLMTSKRDPHEWLDKSWLE 1033

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1066 VSPSEEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKIGSSSITKSPQISSP 1145
Cdd:pfam17825 1034 VSPSKEEMYLLDFPCINPLVAQLMLNKGPSLHWILLATLCQLQELLPEVPEKVLKHFCSITSLFKISSSSITKSPQISSP 1113

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1146 QENRNQISTLSSQSSASDLDSVIQEHNEYYQYLGLGETVQEDKTTILNDNSSIMELKEISSFLPPVTSYNQTSYWKDSSC 1225
Cdd:pfam17825 1114 QENGNQTSTFISQSSASGSDSVIQEHNEYYQYSDLGETVQEDTNTTSNDNSSLMELREMPCVLPPVTSYSQTSYWKDSSC 1193

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1226 KSNIGQNTPFLINIESRRPAYNSFLNHSDSESDVFSLGLTQMNCETIKSPTDTQKRVSvvPRFINSQKRRTHEAKGFINK 1305
Cdd:pfam17825 1194 NPNIVQNNPFLINIESRKVAGNSFLNQNDSESDVFSLGLTQMNCETIISPIDTQRRVA--PNFINYQKKGTHEAKGPINK 1271

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1306 DVSDPIFSLEGTQSPLHWNFKKNIWEQENHPFNLQYGAQQTACNKLYSQKGNLFTDQQKCLSDESEGLTCESSKD---ET 1382
Cdd:pfam17825 1272 EVSAPVFSLEGSQSPLHWNFKKNVWEQQNHSFNLQYGAEQTTCDKWYSQKDNLFTNQQKCLSDELEGLTYESSNAgtkET 1351

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817106  1383 FWRELPSVPSLDLFRASDSNANQKEFNSLYFYQRAGKSLGQKRHHESSFNSGDKESLTGFMCSQLPQFKKRRLAYEKVPG 1462
Cdd:pfam17825 1352 FWRELPSVPSLDLFCASDSNVNQKEFNSLYFYQRAGKCLGQKRHLESSSNSGDKKSLTDLMCSQLPQFKKRRLVYEKVPG 1431

                         1450
                   ....*....|.
gi 578817106  1463 RVDGQTRLRFF 1473
Cdd:pfam17825 1432 RADGQTRLRFF 1442
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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