|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02970 |
PLN02970 |
serine racemase |
5-320 |
1.51e-154 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 436.42 E-value: 1.51e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 5 YCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALErkpKAVVTHSS 84
Cdd:PLN02970 7 YAADLSSIREARKRIAPFIHRTPVLTSSSLDALAGRSLFFKCECFQKGGAFKFRGACNAIFSLSDDQAE---KGVVTHSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 85 GNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQG 164
Cdd:PLN02970 84 GNHAAALALAAKLRGIPAYIVVPKNAPACKVDAVIRYGGIITWCEPTVESREAVAARVQQETGAVLIHPYNDGRVISGQG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 165 TIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVKSSI 244
Cdd:PLN02970 164 TIALEFLEQVPELDVIIVPISGGGLISGIALAAKAIKPSIKIIAAEPKGADDAAQSKAAGEIIT-LPVTNTIADGLRASL 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 245 GLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSP--EVKNICIVLSGGNVDLT 320
Cdd:PLN02970 243 GDLTWPVVRDLVDDVITVDDKEIIEAMKLCYERLKVVVEPSGAIGLAAALSDSFRSNPAwkGCKNVGIVLSGGNVDLG 320
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
9-318 |
2.48e-142 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 404.56 E-value: 2.48e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 9 FADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPdalERKPKAVVTHSSGNHG 88
Cdd:cd01562 1 LEDILAAAARIKPVVRRTPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLLSLSE---EERAKGVVAASAGNHA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 89 QALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIAL 168
Cdd:cd01562 78 QGVAYAAKLLGIPATIVMPETAPAAKVDATRAYGAEVVLYGEDFDEAEAKARELAEEEGLTFIHPFDDPDVIAGQGTIGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 169 EVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVK-SSIGLN 247
Cdd:cd01562 158 EILEQVPDLDAVFVPVGGGGLIAGIATAVKALSPNTKVIGVEPEGAPAMAQSLAAGKPVT-LPEVDTIADGLAvKRPGEL 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578830008 248 TWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQtvsPEVKNICIVLSGGNVD 318
Cdd:cd01562 237 TFEIIRKLVDDVVTVSEDEIAAAMLLLFEREKLVAEPAGALALAALLSGKLD---LKGKKVVVVLSGGNID 304
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
7-320 |
1.63e-122 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 355.11 E-value: 1.63e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERkpkAVVTHSSGN 86
Cdd:COG1171 6 PTLADIEAAAARIAGVVRRTPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALASLSEEERAR---GVVAASAGN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTI 166
Cdd:COG1171 83 HAQGVAYAARLLGIPATIVMPETAPAVKVAATRAYGAEVVLHGDTYDDAEAAAAELAEEEGATFVHPFDDPDVIAGQGTI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 167 ALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVK-SSIG 245
Cdd:COG1171 163 ALEILEQLPDLDAVFVPVGGGGLIAGVAAALKALSPDIRVIGVEPEGAAAMYRSLAAGEPVT-LPGVDTIADGLAvGRPG 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 246 LNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQtvsPEVKNICIVLSGGNVDLT 320
Cdd:COG1171 242 ELTFEILRDLVDDIVTVSEDEIAAAMRLLLERTKIVVEPAGAAALAALLAGKER---LKGKRVVVVLSGGNIDPD 313
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
7-320 |
2.10e-109 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 321.58 E-value: 2.10e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPdalERKPKAVVTHSSGN 86
Cdd:PRK07048 6 PTYDDVAAAAARLAGVAHRTPVLTSRTADARTGAQVFFKCENFQRMGAFKFRGAYNALSQFSP---EQRRAGVVTFSSGN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTI 166
Cdd:PRK07048 83 HAQAIALSARLLGIPATIVMPQDAPAAKVAATRGYGGEVVTYDRYTEDREEIGRRLAEERGLTLIPPYDHPHVIAGQGTA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 167 ALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMpNLYPPETIADGVKS-SIG 245
Cdd:PRK07048 163 AKELFEEVGPLDALFVCLGGGGLLSGCALAARALSPGCKVYGVEPEAGNDGQQSFRSGEIV-HIDTPRTIADGAQTqHLG 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 246 LNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSqhfQTVSPEVKNICIVLSGGNVDLT 320
Cdd:PRK07048 242 NYTFPIIRRLVDDIVTVSDAELVDAMRFFAERMKIVVEPTGCLGAAAALR---GKVPLKGKRVGVIISGGNVDLA 313
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
8-318 |
6.03e-88 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 267.79 E-value: 6.03e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 8 SFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDalERKPKAVVTHSSGNH 87
Cdd:PRK06608 6 NPQNIAAAHNRIKQYLHLTPIVHSESLNEMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQ--GKLPDKIVAYSTGNH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 88 GQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKrvTEETEGIMVHPNQEPAVIAGQGTIA 167
Cdd:PRK06608 84 GQAVAYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVILTNTRQEAEEKAKE--DEEQGFYYIHPSDSDSTIAGAGTLC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 168 LEVLNQVPL-VDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKS-SIG 245
Cdd:PRK06608 162 YEALQQLGFsPDAIFASCGGGGLISGTYLAKELISPTSLLIGSEPLNANDAYLSLKNNKIYRLNYSPNTIADGLKTlSVS 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578830008 246 LNTWPIIRDLvDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPevKNICIVLSGGNVD 318
Cdd:PRK06608 242 ARTFEYLKKL-DDFYLVEEYEIYYWTAWLTHLLKVICEPSSAINMVAVVNWLKTQSKP--QKLLVILSGGNID 311
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
19-314 |
1.20e-86 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 262.63 E-value: 1.20e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 19 IRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPdalERKPKAVVTHSSGNHGQALTYAAKLE 98
Cdd:pfam00291 1 ISLGIGPTPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKE---GEGGKTVVEASSGNHGRALAAAAARL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 99 GIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEG-IMVHPNQEPAVIAGQGTIALEVLNQV-PL 176
Cdd:pfam00291 78 GLKVTIVVPEDAPPGKLLLMRALGAEVVLVGGDYDEAVAAARELAAEGPGaYYINQYDNPLNIEGYGTIGLEILEQLgGD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 177 VDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVKSSI--GLNTWPIIRD 254
Cdd:pfam00291 158 PDAVVVPVGGGGLIAGIARGLKELGPDVRVIGVEPEGAPALARSLAAGRPVP-VPVADTIADGLGVGDepGALALDLLDE 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 255 LVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEvKNICIVLSG 314
Cdd:pfam00291 237 YVGEVVTVSDEEALEAMRLLARREGIVVEPSSAAALAALKLALAGELKGG-DRVVVVLTG 295
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
9-319 |
3.38e-83 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 254.62 E-value: 3.38e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 9 FADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERkpkAVVTHSSGNHG 88
Cdd:PRK06815 4 FDAILEAHQRLRPQVRVTPLEHSPLLSQHTGCEVYLKCEHLQHTGSFKFRGASNKLRLLNEAQRQQ---GVITASSGNHG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 89 QALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIAL 168
Cdd:PRK06815 81 QGVALAAKLAGIPVTVYAPEQASAIKLDAIRALGAEVRLYGGDALNAELAARRAAEQQGKVYISPYNDPQVIAGQGTIGM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 169 EVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVKSSI--GL 246
Cdd:PRK06815 161 ELVEQQPDLDAVFVAVGGGGLISGIATYLKTLSPKTEIIGCWPANSPSLYTSLEAGEIVE-VAEQPTLSDGTAGGVepGA 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 247 NTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQhfqtvSPEV--KNICIVLSGGNVDL 319
Cdd:PRK06815 240 ITFPLCQQLIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALKL-----APRYqgKKVAVVLCGKNIVL 309
|
|
| ilvA_1Cterm |
TIGR01127 |
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the ... |
26-321 |
3.49e-79 |
|
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the C-terminal domain pfam00585 is described by TIGR01124. This model describes a phylogenetically distinct form with a single copy of pfam00585. This form branches with the catabolic threonine dehydratase of E. coli; many members are designated as catabolic for this reason. However, the catabolic form lacks any pfam00585 domain. Many members of this model are found in species with other Ile biosynthetic enzymes. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130197 [Multi-domain] Cd Length: 380 Bit Score: 246.58 E-value: 3.49e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLvpdALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIV 105
Cdd:TIGR01127 1 TPLIYSTTLSDITGSEVYLKLENLQKTGSFKIRGALNKIANL---SEDQRQRGVVAASAGNHAQGVAYAAKKFGIKAVIV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 106 VPQTAPDCKKLAIQAYGASIV-YCEPSDESREnVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPV 184
Cdd:TIGR01127 78 MPESAPPSKVKATKSYGAEVIlHGDDYDEAYA-FATSLAEEEGRVFVHPFDDEFVMAGQGTIGLEIMEDIPDVDTVIVPV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 185 GGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMpNLYPPETIADGVK-SSIGLNTWPIIRDLVDDIFTVT 263
Cdd:TIGR01127 157 GGGGLISGVASAAKQINPNVKVIGVEAEGAPSMYESLREGKIK-AVESVRTIADGIAvKKPGDLTFNIIKEYVDDVVTVD 235
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 264 EDEIKCATQLVWERMKLLIEPTAGVGVAAVLSqhfQTVSPEVKNICIVLSGGNVDLTS 321
Cdd:TIGR01127 236 EEEIANAIYLLLERHKILAEGAGAAGVAALLE---QKVDVKGKKIAVVLSGGNIDLNL 290
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
7-318 |
3.40e-74 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 234.40 E-value: 3.40e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPdalERKPKAVVTHSSGN 86
Cdd:PRK07334 5 VTLADIRAAAARLAGQVLRTPCVHSRTLSQITGAEVWLKFENLQFTASFKERGALNKLLLLTE---EERARGVIAMSAGN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIV-YCEPSDESREnVAKRVTEETEGIMVHPNQEPAVIAGQGT 165
Cdd:PRK07334 82 HAQGVAYHAQRLGIPATIVMPRFTPTVKVERTRGFGAEVVlHGETLDEARA-HARELAEEEGLTFVHPYDDPAVIAGQGT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQsKLKGKLMPNlyPPETIADG--VKsS 243
Cdd:PRK07334 161 VALEMLEDAPDLDTLVVPIGGGGLISGMATAAKALKPDIEIIGVQTELYPSMYA-AIKGVALPC--GGSTIAEGiaVK-Q 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578830008 244 IGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLS--QHFQTvspevKNICIVLSGGNVD 318
Cdd:PRK07334 237 PGQLTLEIVRRLVDDILLVSEADIEQAVSLLLEIEKTVVEGAGAAGLAALLAypERFRG-----RKVGLVLSGGNID 308
|
|
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
7-324 |
1.97e-73 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 230.39 E-value: 1.97e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPdalERKPKAVVTHSSGN 86
Cdd:PRK08638 9 VAIDDIIEAKQRLAGRIRKTPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFNKLSSLTD---AEKRKGVVACSAGN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIV-YCEPSDESRENVAKRVTEETEgIMVHPNQEPAVIAGQGT 165
Cdd:PRK08638 86 HAQGVALSCALLGIDGKVVMPKGAPKSKVAATCGYGAEVVlHGDNFNDTIAKVEEIVEEEGR-TFIPPYDDPKVIAGQGT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMpNLYPPETIADGVKSSI- 244
Cdd:PRK08638 165 IGLEILEDLWDVDTVIVPIGGGGLIAGIAVALKSINPTIHIIGVQSENVHGMAASFYAGEIT-THRTTGTLADGCDVSRp 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 245 GLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVlSGGNVDLT--SS 322
Cdd:PRK08638 244 GNLTYEIVRELVDDIVLVSEDEIRNAMKDLIQRNKVVTEGAGALATAALLSGKLDQYIQNKKVVAII-SGGNVDLSrvSQ 322
|
..
gi 578830008 323 IT 324
Cdd:PRK08638 323 IT 324
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
26-315 |
6.15e-72 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 223.16 E-value: 6.15e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLvpDALERKPKAVVTH-SSGNHGQALTYAAKLEGIPAYI 104
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLA--EEEGKLPKGVIIEsTGGNTGIALAAAAARLGLKCTI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 105 VVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEG-IMVHPNQEPAVIAGQGTIALEVLNQVP--LVDALV 181
Cdd:cd00640 79 VMPEGASPEKVAQMRALGAEVVLVPGDFDDAIALAKELAEEDPGaYYVNQFDNPANIAGQGTIGLEILEQLGgqKPDAVV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 182 VPVGGGGMLAGIAITVKALKPSVKVYAAEPsnaddcyqsklkgklmpnlyppetiadgvkssiglntwpiirdlvdDIFT 261
Cdd:cd00640 159 VPVGGGGNIAGIARALKELLPNVKVIGVEP----------------------------------------------EVVT 192
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 578830008 262 VTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTvsPEVKNICIVLSGG 315
Cdd:cd00640 193 VSDEEALEAIRLLAREEGILVEPSSAAALAAALKLAKKL--GKGKTVVVILTGG 244
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
7-319 |
1.81e-70 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 222.15 E-value: 1.81e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERkpkAVVTHSSGN 86
Cdd:PRK07476 1 VSLADIYRARRRIAGRVRRTPLVASASLSARAGVPVWLKLETLQPTGSFKLRGATNALLSLSAQERAR---GVVTASTGN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPS-DESRENVAkRVTEETEGIMVHPNQEPAVIAGQGT 165
Cdd:PRK07476 78 HGRALAYAARALGIRATICMSRLVPANKVDAIRALGAEVRIVGRSqDDAQAEVE-RLVREEGLTMVPPFDDPRIIAGQGT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKlmP-NLYPPETIADGVKSSI 244
Cdd:PRK07476 157 IGLEILEALPDVATVLVPLSGGGLASGVAAAVKAIRPAIRVIGVSMERGAAMHASLAAGR--PvQVEEVPTLADSLGGGI 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 245 GLN---TWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSqhfQTVSPEVKNICIVLSGGNVDL 319
Cdd:PRK07476 235 GLDnryTFAMCRALLDDVVLLDEAEIAAGIRHAYREERLVVEGAGAVGIAALLA---GKIAARDGPIVVVVSGANIDM 309
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
7-321 |
2.50e-62 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 200.95 E-value: 2.50e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSIlNQLTGRNLFFKCELFQKTGSFKIRGALNAVRS-LVPDAlerkpkAVVTHSSG 85
Cdd:PRK08246 5 ITRSDVRAAAQRIAPHIRRTPVLEADG-AGFGPAPVWLKLEHLQHTGSFKARGAFNRLLAaPVPAA------GVVAASGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 86 NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGT 165
Cdd:PRK08246 78 NAGLAVAYAAAALGVPATVFVPETAPPAKVARLRALGAEVVVVGAEYADALEAAQAFAAETGALLCHAYDQPEVLAGAGT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPLVDALVVPVGGGGMLAGIAitvKALKPSVKVYAAEPSNADDCYQSKLKGKlmpnlyPPETIADGVKSS-- 243
Cdd:PRK08246 158 LGLEIEEQAPGVDTVLVAVGGGGLIAGIA---AWFEGRARVVAVEPEGAPTLHAALAAGE------PVDVPVSGIAADsl 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 244 ----IGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEvkNICIVLSGGNVDL 319
Cdd:PRK08246 229 garrVGEIAFALARAHVVTSVLVSDEAIIAARRALWEELRLAVEPGAATALAALLSGAYVPAPGE--RVAVVLCGANTDP 306
|
..
gi 578830008 320 TS 321
Cdd:PRK08246 307 AT 308
|
|
| ectoine_eutB |
TIGR02991 |
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted ... |
7-319 |
1.24e-57 |
|
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted arylmalonate decarboxylase found in a conserved ectoine utilization operon of species that include Sinorhizobium meliloti 1021 (where it is known to be induced by ectoine), Mesorhizobium loti, Silicibacter pomeroyi, Agrobacterium tumefaciens, and Pseudomonas putida. Members of this family resemble threonine dehydratases.
Pssm-ID: 132036 [Multi-domain] Cd Length: 317 Bit Score: 188.91 E-value: 1.24e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLvpDALERKpKAVVTHSSGN 86
Cdd:TIGR02991 1 VTLQDIERAAARISGRVEETPLVESPSLSELCGVPVHLKLEHRQTTGSFKLRGATNAVLSL--SDTQRA-AGVVAASTGN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASI-VYCEPSDESRENVaKRVTEETEGIMVHPNQEPAVIAGQGT 165
Cdd:TIGR02991 78 HGRALAYAAAEEGVRATICMSELVPQNKVDEIRRLGAEVrIVGRSQDDAQEEV-ERLVADRGLTMLPPFDHPDIVAGQGT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKlmPNLYPPE-TIADGVKSSI 244
Cdd:TIGR02991 157 LGLEVVEQMPDLATVLVPLSGGGLASGVAMAVKAARPDTRVIGVSMERGAAMKASLQAGR--PVLVAELpTLADSLGGGI 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 245 GLN---TWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPevknICIVLSGGNVDL 319
Cdd:TIGR02991 235 GLDnrvTFAMCKALLDEIVLVSEAEIAAGIRHAYAEEREIVEGAGAVGIAALLAGKIKNPGP----CAVIVSGRNIDM 308
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
26-317 |
8.82e-55 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 186.50 E-value: 8.82e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERkpkAVVTHSSGNHGQALTYAAKLEGIPAYIV 105
Cdd:PRK09224 21 TPLEKAPKLSARLGNQVLLKREDLQPVFSFKLRGAYNKMAQLTEEQLAR---GVITASAGNHAQGVALSAARLGIKAVIV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 106 VPQTAPDCKKLAIQAYGASIV-YCEPSDESRENvAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVP-LVDALVVP 183
Cdd:PRK09224 98 MPVTTPDIKVDAVRAFGGEVVlHGDSFDEAYAH-AIELAEEEGLTFIHPFDDPDVIAGQGTIAMEILQQHPhPLDAVFVP 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 184 VGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKlmpnlypPETI------ADG--VKsSIGLNTWPIIRDL 255
Cdd:PRK09224 177 VGGGGLIAGVAAYIKQLRPEIKVIGVEPEDSACLKAALEAGE-------RVDLpqvglfADGvaVK-RIGEETFRLCQEY 248
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578830008 256 VDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAvLSQHFQTVSPEVKNICIVLSGGNV 317
Cdd:PRK09224 249 VDDVITVDTDEICAAIKDVFEDTRSIAEPAGALALAG-LKKYVAQHGIEGETLVAILSGANM 309
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
26-318 |
1.32e-54 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 186.54 E-value: 1.32e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERkpkAVVTHSSGNHGQALTYAAKLEGIPAYIV 105
Cdd:PRK12483 38 TPLQRAPNLSARLGNQVLLKREDLQPVFSFKIRGAYNKMARLPAEQLAR---GVITASAGNHAQGVALAAARLGVKAVIV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 106 VPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVP-LVDALVVPV 184
Cdd:PRK12483 115 MPRTTPQLKVDGVRAHGGEVVLHGESFPDALAHALKLAEEEGLTFVPPFDDPDVIAGQGTVAMEILRQHPgPLDAIFVPV 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 185 GGGGMLAGIAITVKALKPSVKVYAAEPSNAdDCYQSKLKGKLMPNLYPPETIADGVK-SSIGLNTWPIIRDLVDDIFTVT 263
Cdd:PRK12483 195 GGGGLIAGIAAYVKYVRPEIKVIGVEPDDS-NCLQAALAAGERVVLGQVGLFADGVAvAQIGEHTFELCRHYVDEVVTVS 273
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 264 EDEIKCATQLVWERMKLLIEPTAGVGVAAvLSQHFQTVSPEVKNICIVLSGGNVD 318
Cdd:PRK12483 274 TDELCAAIKDIYDDTRSITEPAGALAVAG-IKKYAEREGIEGQTLVAIDSGANVN 327
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
7-318 |
3.05e-53 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 180.39 E-value: 3.05e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALErkpKAVVTHSSGN 86
Cdd:PRK08639 7 VSAKDIDKAAKRLKDVVPETPLQRNDYLSEKYGANVYLKREDLQPVRSYKLRGAYNAISQLSDEELA---AGVVCASAGN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 87 HGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGAS----IVYCEPSDESrENVAKRVTEETEGIMVHPNQEPAVIAG 162
Cdd:PRK08639 84 HAQGVAYACRHLGIPGVIFMPVTTPQQKIDQVRFFGGEfveiVLVGDTFDDS-AAAAQEYAEETGATFIPPFDDPDVIAG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 163 QGTIALEVLNQV---PLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKL--MPNLyppETIA 237
Cdd:PRK08639 163 QGTVAVEILEQLekeGSPDYVFVPVGGGGLISGVTTYLKERSPKTKIIGVEPAGAASMKAALEAGKPvtLEKI---DKFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 238 DG--VKsSIGLNTWPIIRDLVDDIFTVTEDEIkCATQLvwermKLL------IEPtAGVGVAAVLSQHFQTVspEVKNIC 309
Cdd:PRK08639 240 DGaaVA-RVGDLTFEILKDVVDDVVLVPEGAV-CTTIL-----ELYnkegivAEP-AGALSIAALELYKDEI--KGKTVV 309
|
....*....
gi 578830008 310 IVLSGGNVD 318
Cdd:PRK08639 310 CVISGGNND 318
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
24-318 |
1.02e-40 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 150.46 E-value: 1.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 24 HLTPVLTSSI--------------LNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALErkpKAVVTHSSGNHGQ 89
Cdd:PLN02550 94 YLTNILSAKVydvaiesplqlakkLSERLGVKVLLKREDLQPVFSFKLRGAYNMMAKLPKEQLD---KGVICSSAGNHAQ 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 90 ALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALE 169
Cdd:PLN02550 171 GVALSAQRLGCDAVIAMPVTTPEIKWQSVERLGATVVLVGDSYDEAQAYAKQRALEEGRTFIPPFDHPDVIAGQGTVGME 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 170 VLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMpNLYPPETIADGVK-SSIGLN 247
Cdd:PLN02550 251 IVRQHQgPLHAIFVPVGGGGLIAGIAAYVKRVRPEVKIIGVEPSDANAMALSLHHGERV-MLDQVGGFADGVAvKEVGEE 329
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578830008 248 TWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVlSQHFQTVSPEVKNICIVLSGGNVD 318
Cdd:PLN02550 330 TFRLCRELVDGVVLVSRDAICASIKDMFEEKRSILEPAGALALAGA-EAYCKYYGLKDENVVAITSGANMN 399
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
7-320 |
2.09e-38 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 139.76 E-value: 2.09e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 7 ISFADVEKAHINIRDSIHLTPVLTSSILNqltgrnLFFKCELFQKTGSFKIRGALNAVRSlvpdALER-KPKAVVTHSSG 85
Cdd:PRK08813 21 VSVADVLAAQARLRRYLSPTPLHYAERFG------VWLKLENLQRTGSYKVRGALNALLA----GLERgDERPVICASAG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 86 NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGT 165
Cdd:PRK08813 91 NHAQGVAWSAYRLGVQAITVMPHGAPQTKIAGVAHWGATVRQHGNSYDEAYAFARELADQNGYRFLSAFDDPDVIAGQGT 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 166 IALEVLNQVPlvDALVVPVGGGGMLAGIAITVKAlkPSVKVYAAEPSNADDCYQSkLKGKLMpNLYPPETIADGVKSSI- 244
Cdd:PRK08813 171 VGIELAAHAP--DVVIVPIGGGGLASGVALALKS--QGVRVVGAQVEGVDSMARA-IRGDLR-EIAPVATLADGVKVKIp 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578830008 245 GLNTWPIIRDLVDDIFTVTEDEIK-CATQLVWERmKLLIEPTAGVGVAAvlsqhFQTVSPEVKniCIVLSGGNVDLT 320
Cdd:PRK08813 245 GFLTRRLCSSLLDDVVIVREAELReTLVRLALEE-HVIAEGAGALALAA-----GRRVSGKRK--CAVVSGGNIDAT 313
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
9-294 |
5.34e-37 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 136.87 E-value: 5.34e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 9 FADVEKAhINIRDSIhlTPVLTSSILNQLTGRNLFFKcELFQ-KTGSFKIRGAlnAVrsLVPDALERKPKAVVTHSSGNH 87
Cdd:COG0498 53 FDDEEKA-VSLGEGG--TPLVKAPRLADELGKNLYVK-EEGHnPTGSFKDRAM--QV--AVSLALERGAKTIVCASSGNG 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 88 GQAL-TYAAKlEGIPAYIVVPQT-APDCKKLAIQAYGASIVYCEPS-DEsRENVAKRVTEETEGIMVHpNQEPAVIAGQG 164
Cdd:COG0498 125 SAALaAYAAR-AGIEVFVFVPEGkVSPGQLAQMLTYGAHVIAVDGNfDD-AQRLVKELAADEGLYAVN-SINPARLEGQK 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 165 TIALEV---LNQVPlvDALVVPVGGGGMLAGIAitvKALK-----------PsvKVYAAEPSNADDCYQSKLKGKLMPNL 230
Cdd:COG0498 202 TYAFEIaeqLGRVP--DWVVVPTGNGGNILAGY---KAFKelkelglidrlP--RLIAVQATGCNPILTAFETGRDEYEP 274
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578830008 231 YPPETIADGVksSIG--LNTWPIIRDLVD---DIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVL 294
Cdd:COG0498 275 ERPETIAPSM--DIGnpSNGERALFALREsggTAVAVSDEEILEAIRLLARREGIFVEPATAVAVAGLR 341
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
26-312 |
6.75e-37 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 134.18 E-value: 6.75e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRslvpDALER---KPKA-VVTHSSGNHGQALTYAAKLEGIP 101
Cdd:cd01561 3 TPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIE----DAEKRgllKPGTtIIEPTSGNTGIGLAMVAAAKGYR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 102 AYIVVPQTAPDCKKLAIQAYGASIVYCEPSD----ESRENVAKRVTEETEGImVHPNQ--EPA-VIAGQGTIALEVLNQV 174
Cdd:cd01561 79 FIIVMPETMSEEKRKLLRALGAEVILTPEAEadgmKGAIAKARELAAETPNA-FWLNQfeNPAnPEAHYETTAPEIWEQL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 175 P-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADdcyqsklkgkLMPNLYPPETIADGvkssIGLNTWPII- 252
Cdd:cd01561 158 DgKVDAFVAGVGTGGTITGVARYLKEKNPNVRIVGVDPVGSV----------LFSGGPPGPHKIEG----IGAGFIPENl 223
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578830008 253 -RDLVDDIFTVTEDE-IKCATQLVwERMKLLIEPTAGVGVAAVLsqHFQTVSPEVKNICIVL 312
Cdd:cd01561 224 dRSLIDEVVRVSDEEaFAMARRLA-REEGLLVGGSSGAAVAAAL--KLAKRLGPGKTIVTIL 282
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
8-332 |
1.38e-36 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 133.97 E-value: 1.38e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 8 SFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVpdALERKPKAVVTHSSGNH 87
Cdd:PRK06110 4 TLAELEAAAAVVYAAMPPTPQYRWPLLAERLGCEVWVKHENHTPTGAFKVRGGLVYFDRLA--RRGPRVRGVISATRGNH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 88 GQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIV-YCEPSDESRENvAKRVTEETEGIMVhPNQEPAVIAGQGTI 166
Cdd:PRK06110 82 GQSVAFAARRHGLAATIVVPHGNSVEKNAAMRALGAELIeHGEDFQAAREE-AARLAAERGLHMV-PSFHPDLVRGVATY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 167 ALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNlypP--ETIADGVKSSI 244
Cdd:PRK06110 160 ALELFRAVPDLDVVYVPIGMGSGICGAIAARDALGLKTRIVGVVSAHAPAYALSFEAGRVVTT---PvaTTLADGMACRT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 245 GL-NTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTvspEVKNICIVLSGGNVDLTSSI 323
Cdd:PRK06110 237 PDpEALEVIRAGADRIVRVTDDEVAAAMRAYFTDTHNVAEGAGAAALAAALQERERL---AGKRVGLVLSGGNIDRAVFA 313
|
....*....
gi 578830008 324 TWVKQAERP 332
Cdd:PRK06110 314 RVLAGAAAE 322
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
26-316 |
2.39e-34 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 128.19 E-value: 2.39e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPkAVVTHSSGNHGQALTYAAKLEGIPAYIV 105
Cdd:cd06448 2 TPLIESTALSKTAGCNVFLKLENLQPSGSFKIRGIGHLCQKSAKQGLNECV-HVVCSSGGNAGLAAAYAARKLGVPCTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 106 VPQTAPDCKKLAIQAYGASIV-----YCEPSDESRENVAKRvteETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL---V 177
Cdd:cd06448 81 VPESTKPRVVEKLRDEGATVVvhgkvWWEADNYLREELAEN---DPGPVYVHPFDDPLIWEGHSSMVDEIAQQLQSqekV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 178 DALVVPVGGGGMLAGIaitVKALK----PSVKVYAAEPSNADDCYQSKLKGKLMPnLYPPETIADGVKSS-IGLNTW--- 249
Cdd:cd06448 158 DAIVCSVGGGGLLNGI---VQGLErngwGDIPVVAVETEGAHSLNASLKAGKLVT-LPKITSVATSLGAKtVSSQALeya 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 250 ---PIIRDLVDDIFTVTedeikcATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVK-----NICIVLSGGN 316
Cdd:cd06448 234 qehNIKSEVVSDRDAVQ------ACLRFADDERILVEPACGAALAVVYSGKILDLQLEVLltpldNVVVVVCGGS 302
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
26-294 |
3.80e-33 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 125.01 E-value: 3.80e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSIL-NQLTGRNLFFKCELFQKTGSFKIRGALNAVRSlvpdALERKPKAVVTHSSGNHGQAL-TYAAKlEGIPAY 103
Cdd:cd01563 23 TPLVRAPRLgERLGGKNLYVKDEGLNPTGSFKDRGMTVAVSK----AKELGVKAVACASTGNTSASLaAYAAR-AGIKCV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 104 IVVPQTAPDCKKLAIQAYGASIVycePSDESRENVAKRVTEETE--GIMVHPNQEPAVIAGQGTIALEVLNQ----VPlv 177
Cdd:cd01563 98 VFLPAGKALGKLAQALAYGATVL---AVEGNFDDALRLVRELAEenWIYLSNSLNPYRLEGQKTIAFEIAEQlgweVP-- 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 178 DALVVPVGGGGMLAGIAITVKALKPS------VKVYAAEPSNADDCYQSKLKGKLMPNLYP-PETIADGVKssIGlN--T 248
Cdd:cd01563 173 DYVVVPVGNGGNITAIWKGFKELKELglidrlPRMVGVQAEGAAPIVRAFKEGKDDIEPVEnPETIATAIR--IG-NpaS 249
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 578830008 249 WPIIRDLVD----DIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVL 294
Cdd:cd01563 250 GPKALRAVResggTAVAVSDEEILEAQKLLARTEGIFVEPASAASLAGLK 299
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
18-266 |
2.53e-30 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 116.69 E-value: 2.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRgalnAVRSLVPDALER---KP-KAVVTHSSGNHGQALTY 93
Cdd:COG0031 6 SILELIGNTPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDR----IALSMIEDAEKRgllKPgGTIVEATSGNTGIGLAM 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 94 AAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSD--ESRENVAKRVTEETEGiMVHPNQ--EPA-VIAGQGTIAL 168
Cdd:COG0031 82 VAAAKGYRLILVMPETMSKERRALLRAYGAEVVLTPGAEgmKGAIDKAEELAAETPG-AFWPNQfeNPAnPEAHYETTGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 169 EVLNQVPL-VDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNA-----DDCYQSKLKGklmpnlyppetiadgvks 242
Cdd:COG0031 161 EIWEQTDGkVDAFVAGVGTGGTITGVGRYLKERNPDIKIVAVEPEGSpllsgGEPGPHKIEG------------------ 222
|
250 260
....*....|....*....|....*.
gi 578830008 243 sIGLNTWP--IIRDLVDDIFTVTEDE 266
Cdd:COG0031 223 -IGAGFVPkiLDPSLIDEVITVSDEE 247
|
|
| thrC |
TIGR00260 |
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction ... |
33-318 |
3.19e-24 |
|
threonine synthase; Involved in threonine biosynthesis it catalyses the reaction O-PHOSPHO-L-HOMOSERINE + H(2)O = L-THREONINE + ORTHOPHOSPHATE using pyridoxal phosphate as a cofactor. the enzyme is distantly related to the serine/threonine dehydratases which are also pyridoxal-phosphate dependent enzymes. the pyridoxal-phosphate binding site is a Lys (K) residues present at residue 70 of the model. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 272986 [Multi-domain] Cd Length: 327 Bit Score: 100.92 E-value: 3.19e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 33 ILNQLTGRNLFFKCELFQKTGSFKIRGalnaVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPD 112
Cdd:TIGR00260 31 LAANVGIKNLYVKELGHNPTLSFKDRG----MAVALTKALELGNDTVLCASTGNTGAAAAAYAGKAGLKVVVLYPAGKIS 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 113 CKKLAIQ-AYGASIVYCEPSDESRENVAKRVTEETEGIMVHP-NQEPAVIAGQGTIALEVLNQVP--LVDALVVPVGGGG 188
Cdd:TIGR00260 107 LGKLAQAlGYNAEVVAIDGNFDDAQRLVKQLFEDKPALGLNSaNSIPYRLEGQKTYAFEAVEQLGweAPDKVVVPVPNSG 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 189 MLAGIAITVKALK-------PsvKVYAAEPSNADDCYQSKLKGKlmpNLYP---PETIA---DGVKSSIGLNTWPIIRDL 255
Cdd:TIGR00260 187 NFGAIWKGFKEKKmlgldslP--VKRGIQAEGAADIVRAFLEGG---QWEPietPETLStamDIGNPANWPRALEAFRRS 261
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578830008 256 VDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQ-TVSPEVKNICIVLSGGNVD 318
Cdd:TIGR00260 262 NGYAEDLSDEEILEAIKLLAREEGYFVEPHSAVAVAALLKLVEKgTADPAERVVCALTGNGLKD 325
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
24-319 |
2.73e-20 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 90.27 E-value: 2.73e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 24 HLTPVLTSSILnqlTGRNLFFKCELFQKTGSFKIRGALNAVRSLvpdaLERKPKAVVTHSSGNHGQALTYAAKLEGIPAY 103
Cdd:PRK08329 59 HLTPPITPTVK---RSIKVYFKLDYLQPTGSFKDRGTYVTVAKL----KEEGINEVVIDSSGNAALSLALYSLSEGIKVH 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 104 IVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVP 183
Cdd:PRK08329 132 VFVSYNASKEKISLLSRLGAELHFVEGDRMEVHEEAVKFSKRNNIPYVSHWLNPYFLEGTKTIAYEIYEQIGVPDYAFVP 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 184 VGGGGMLAGIAITVKALK--------PSVKVYAAEPSNAdDCYQSKLKGKL-----MPNlyPP--ETIADGVKSSIGLnt 248
Cdd:PRK08329 212 VGSGTLFLGIWKGFKELHemgeiskmPKLVAVQAEGYES-LCKRSKSENKLadgiaIPE--PPrkEEMLRALEESNGF-- 286
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578830008 249 wpiirdlvddIFTVTEDEIKCAtqLVW-ERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDL 319
Cdd:PRK08329 287 ----------CISVGEEETRAA--LHWlRRMGFLVEPTSAVALAAYWKLLEEGLIEGGSKVLLPLSGSGLKN 346
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
26-314 |
1.49e-18 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 86.02 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLtGRNLFFKCELFQKTGSFKIRGALNAVRslvpDALERKPKAVVTHSSGNHGQALT-YAAKlEGIPAYI 104
Cdd:PRK05638 67 TPLIRARISEKL-GENVYIKDETRNPTGSFRDRLATVAVS----YGLPYAANGFIVASDGNAAASVAaYSAR-AGKEAFV 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 105 VVPQTAPDCKKLAIQAYGAS-IVYCEPSDESREnVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQV-PlvDALVV 182
Cdd:PRK05638 141 VVPRKVDKGKLIQMIAFGAKiIRYGESVDEAIE-YAEELARLNGLYNVTPEYNIIGLEGQKTIAFELWEEInP--THVIV 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 183 PVGGGGMLAGI------AITVKALKPSVKVYAAEPSNADDCYQS------KLKGKLMPNLYppetIADGVKSSIGLNtwp 250
Cdd:PRK05638 218 PTGSGSYLYSIykgfkeLLEIGVIEEIPKLIAVQTERCNPIASEilgnktKCNETKALGLY----VKNPVMKEYVSE--- 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578830008 251 IIRDLVDDIFTVTEDEIKCATQLVWERmKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSG 314
Cdd:PRK05638 291 AIKESGGTAVVVNEEEIMAGEKLLAKE-GIFAELSSAVVMPALLKLGEEGYIEKGDKVVLVVTG 353
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
18-211 |
7.31e-17 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 79.91 E-value: 7.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRslvpDALER---KP-KAVVTHSSGNHGQALTY 93
Cdd:PRK10717 6 DVSDTIGNTPLIRLNRASEATGCEILGKAEFLNPGGSVKDRAALNIIW----DAEKRgllKPgGTIVEGTAGNTGIGLAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 94 AAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESREN----VAKRVTEEtegiMVHPNQEPAVIAGQ------ 163
Cdd:PRK10717 82 VAAARGYKTVIVMPETQSQEKKDLLRALGAELVLVPAAPYANPNnyvkGAGRLAEE----LVASEPNGAIWANQfdnpan 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 578830008 164 -----GTIALEVLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEP 211
Cdd:PRK10717 158 reahyETTGPEIWEQTDgKVDGFVCAVGTGGTLAGVSRYLKETNPKVKIVLADP 211
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
26-193 |
1.70e-16 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 78.98 E-value: 1.70e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVLTSSILNQLTG-RNLFFKCELFQKTGSFKIRGALNAVRslvpDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYI 104
Cdd:PRK06381 16 TPLLRARKLEEELGlRKIYLKFEGANPTGTQKDRIAEAHVR----RAMRLGYSGITVGTCGNYGASIAYFARLYGLKAVI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 105 VVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIA--GQGTIALEVLNQVPLV-DALV 181
Cdd:PRK06381 92 FIPRSYSNSRVKEMEKYGAEIIYVDGKYEEAVERSRKFAKENGIYDANPGSVNSVVDieAYSAIAYEIYEALGDVpDAVA 171
|
170
....*....|..
gi 578830008 182 VPVGGGGMLAGI 193
Cdd:PRK06381 172 VPVGNGTTLAGI 183
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
19-314 |
8.76e-15 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 74.00 E-value: 8.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 19 IRDSIHLTPVLTSSIlnqlTGRNLFFKCELFQKTGSFKIRGAlnavRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLE 98
Cdd:PRK06450 48 IKHFISLGEGRTPLI----KKGNIWFKLDFLNPTGSYKDRGS----VTLISYLAEKGIKQISEDSSGNAGASIAAYGAAA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 99 GIPAYIVVPQTAPDCKKLAIQAYGASIVYCEpsdESRENVAKrVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQ----V 174
Cdd:PRK06450 120 GIEVKIFVPETASGGKLKQIESYGAEVVRVR---GSREDVAK-AAENSGYYYASHVLQPQFRDGIRTLAYEIAKDldwkI 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 175 PlvDALVVPVGGGGMLAGIAITVKALKPS------VKVYAAEPSNADDCYqSKLKGKlmpNLYPPE---TIADGVKSsig 245
Cdd:PRK06450 196 P--NYVFIPVSAGTLLLGVYSGFKHLLDSgvisemPKIVAVQTEQVSPLC-AKFKGI---SYTPPDkvtSIADALVS--- 266
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578830008 246 lnTWPIIRDLVDDIF-------TVTEDEIKCAtqlvWE---RMKLLIEPTAGVGVAAvlsqhFQTVSPEvkNICIVLSG 314
Cdd:PRK06450 267 --TRPFLLDYMVKALseygeciVVSDNEIVEA----WKelaKKGLLVEYSSATVYAA-----YKKYSVN--DSVLVLTG 332
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
25-201 |
1.08e-14 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 74.27 E-value: 1.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 25 LTPVLTSSILNQLTG-RNLFFKCELFQKTGSFKIRGALNAVRSlvpdALERKPKAVVTHSSGNHGQAL-TYAAKLeGIPA 102
Cdd:PRK08197 79 MTPLLPLPRLGKALGiGRLWVKDEGLNPTGSFKARGLAVGVSR----AKELGVKHLAMPTNGNAGAAWaAYAARA-GIRA 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 103 YIVVPQTAPDCKKLAIQAYGASIVYCEP--SDESREnVAKRVTEetEGIM-VHPNQEPAVIAGQGTIALEVLNQ----VP 175
Cdd:PRK08197 154 TIFMPADAPEITRLECALAGAELYLVDGliSDAGKI-VAEAVAE--YGWFdVSTLKEPYRIEGKKTMGLELAEQlgwrLP 230
|
170 180
....*....|....*....|....*.
gi 578830008 176 lvDALVVPVGGGGMLAGIaitVKALK 201
Cdd:PRK08197 231 --DVILYPTGGGVGLIGI---WKAFD 251
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
53-295 |
1.69e-14 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 73.76 E-value: 1.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 53 GSFKIRGALNAV------------RSLVPDAL---ERKPKA----VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDC 113
Cdd:PRK08206 74 NAFKALGGAYAVarllaeklgldiSELSFEELtsgEVREKLgditFATATDGNHGRGVAWAAQQLGQKAVIYMPKGSSEE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 114 KKLAIQAYGASIV-----YcepsDES-REnvAKRVTEETEGIMVhpnQEPA----------VIAGQGTIALEVLNQVPlv 177
Cdd:PRK08206 154 RVDAIRALGAECIitdgnY----DDSvRL--AAQEAQENGWVVV---QDTAwegyeeiptwIMQGYGTMADEAVEQLK-- 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 178 DALVVP--------VGG--GGMLAGIAITVKALKPSVKVyaAEPSNADDCYQSKLKGKLmpnlyppeTIADGVKSSI--G 245
Cdd:PRK08206 223 EMGVPPthvflqagVGSlaGAVLGYFAEVYGEQRPHFVV--VEPDQADCLYQSAVDGKP--------VAVTGDMDTImaG 292
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 246 LN-------TWPIIRDLVDDIFTVTEDEIKCAtqlvwerMKLLIEPTAG-----------VGVAAVLS 295
Cdd:PRK08206 293 LAcgepnplAWEILRNCADAFISCPDEVAALG-------MRILANPLGGdppivsgesgaVGLGALAA 353
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
18-294 |
5.57e-10 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 59.97 E-value: 5.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 18 NIRDS----IHLTPVLtssILNQLT---GRNLFFKCELFQKTGSFKIRGALnavrSLVPDALERK-----PKAVVTHSSG 85
Cdd:PLN02556 48 KIKTDasqlIGKTPLV---YLNKVTegcGAYIAAKQEMFQPTSSIKDRPAL----AMIEDAEKKNlitpgKTTLIEPTSG 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 86 NHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAK--RVTEET-EGIMVHPNQEPA-VIA 161
Cdd:PLN02556 121 NMGISLAFMAAMKGYKMILTMPSYTSLERRVTMRAFGAELVLTDPTKGMGGTVKKayELLESTpDAFMLQQFSNPAnTQV 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 162 GQGTIALEVL-NQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKlkgklmPNlyPPETIADGV 240
Cdd:PLN02556 201 HFETTGPEIWeDTLGQVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYGVEPAESNVLNGGK------PG--PHHITGNGV 272
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 578830008 241 kssiGLNTWPIIRDLVDDIFTVT-EDEIKCATQLVWERmKLLIEPTAGVGVAAVL 294
Cdd:PLN02556 273 ----GFKPDILDMDVMEKVLEVSsEDAVNMARELALKE-GLMVGISSGANTVAAL 322
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
21-211 |
8.65e-09 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 56.54 E-value: 8.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 21 DSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNavrsLVPDALERK---PKAVVTH-SSGNHGQALTYAAK 96
Cdd:PLN02356 49 DAIGNTPLIRINSLSEATGCEILGKCEFLNPGGSVKDRVAVK----IIEEALESGqlfPGGVVTEgSAGSTAISLATVAP 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 97 LEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEP----------------SDESRENVAKR---------VTEETEGIMV 151
Cdd:PLN02356 125 AYGCKCHVVIPDDVAIEKSQILEALGATVERVRPvsithkdhyvniarrrALEANELASKRrkgsetdgiHLEKTNGCIS 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 152 HPNQEPAVIAG---------------------QGTiALEVLNQVPL-VDALVVPVGGGGMLAGIAITVKALKPSVKVYAA 209
Cdd:PLN02356 205 EEEKENSLFSSsctggffadqfenlanfrahyEGT-GPEIWEQTQGnLDAFVAAAGTGGTLAGVSRFLQEKNPNIKCFLI 283
|
..
gi 578830008 210 EP 211
Cdd:PLN02356 284 DP 285
|
|
| PLN02569 |
PLN02569 |
threonine synthase |
52-192 |
5.73e-08 |
|
threonine synthase
Pssm-ID: 178182 [Multi-domain] Cd Length: 484 Bit Score: 54.05 E-value: 5.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 52 TGSFKIRGALNAVrSLVpDALERKPK---AVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLaIQ--AYGASIV 126
Cdd:PLN02569 162 TGSFKDLGMTVLV-SQV-NRLRKMAKpvvGVGCASTGDTSAALSAYCAAAGIPSIVFLPADKISIAQL-VQpiANGALVL 238
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 127 YCEPSDESRENVAKRVTEETEgIMVHPNQEPAVIAGQGTIALEVLNQ----VPlvDALVVPVGGGGMLAG 192
Cdd:PLN02569 239 SIDTDFDGCMRLIREVTAELP-IYLANSLNSLRLEGQKTAAIEILQQfdweVP--DWVIVPGGNLGNIYA 305
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
18-294 |
5.22e-06 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 47.85 E-value: 5.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALnavrSLVPDALERK-----PKAVVTHSSGNHGQALT 92
Cdd:PLN03013 116 NVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGY----SMVTDAEQKGfispgKSVLVEPTSGNTGIGLA 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 93 YAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENV--AKRVTEET-EGIMVHPNQEPAVIAGQ-GTIAL 168
Cdd:PLN03013 192 FIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVqkAEEILKNTpDAYMLQQFDNPANPKIHyETTGP 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 169 EVLNQVP-LVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKlkgklmPNLYPPETIADGVkssIGLN 247
Cdd:PLN03013 272 EIWDDTKgKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGK------PGPHKIQGIGAGF---IPKN 342
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 578830008 248 twpIIRDLVDDIFTVTEDE-IKCATQLVWERmKLLIEPTAGVGVAAVL 294
Cdd:PLN03013 343 ---LDQKIMDEVIAISSEEaIETAKQLALKE-GLMVGISSGAAAAAAI 386
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
19-150 |
9.86e-06 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 46.40 E-value: 9.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 19 IRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSlvpdALER---KPKAV-VTHSSGNHGQALTYA 94
Cdd:PRK11761 6 LEDTIGNTPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALSMIVQ----AEKRgeiKPGDTlIEATSGNTGIALAMI 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 578830008 95 AKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCePSDESRE---NVAKRVTEETEGIM 150
Cdd:PRK11761 82 AAIKGYRMKLIMPENMSQERRAAMRAYGAELILV-PKEQGMEgarDLALQMQAEGEGKV 139
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
45-323 |
9.92e-06 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 46.53 E-value: 9.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 45 KCELFQKTGSFKIRGALNAVRSLVPDALERKPKA-VVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGA 123
Cdd:PLN00011 37 KLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGKStLIEATAGNTGIGLACIGAARGYKVILVMPSTMSLERRIILRALGA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 124 SIVYCEPSDESR---ENVAKRVTEETEGIMVHPNQEPAVIAGQ-GTIALEVL-NQVPLVDALVVPVGGGGMLAGIAITVK 198
Cdd:PLN00011 117 EVHLTDQSIGLKgmlEKAEEILSKTPGGYIPQQFENPANPEIHyRTTGPEIWrDSAGKVDILVAGVGTGGTATGVGKFLK 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 199 ALKPSVKVYAAEPSnaddcyQSKLKGKLMPNLYPPETIADG-VKSSIGLNtwpiirdLVDDIFTVTEDEIKCATQLVWER 277
Cdd:PLN00011 197 EKNKDIKVCVVEPV------ESAVLSGGQPGPHLIQGIGSGiIPFNLDLT-------IVDEIIQVTGEEAIETAKLLALK 263
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 578830008 278 MKLLIEPTAGVGVAAVLSqhfQTVSPEVKNICIVL---SGGNVDLTSSI 323
Cdd:PLN00011 264 EGLLVGISSGAAAAAALK---VAKRPENAGKLIVVifpSGGERYLSTKL 309
|
|
| ACCD |
cd06449 |
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme ... |
26-206 |
4.20e-04 |
|
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia.
Pssm-ID: 107210 Cd Length: 307 Bit Score: 41.64 E-value: 4.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 26 TPVltsSILNQLTgRNLFFKCELFQK----TGSFKIRGalNAVRSL---VPDALERKPKAVVT----HSsgNHGQALTYA 94
Cdd:cd06449 1 TPI---QYLPRLS-EHLGGKVEIYAKrddcNSGLAFGG--NKIRKLeylLPDALAKGADTLVTvggiQS--NHTRQVAAV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578830008 95 AKLEGIPAYIV----VPQTAPDCKK----LAIQAYGASIVYCEPS-----DESRENVAKRVTEE-------TEGIMVHPn 154
Cdd:cd06449 73 AAKLGLKCVLVqenwVPYSDAVYDRvgniLLSRIMGADVRLVSAGfdigiRKSFEEAAEEVEAKggkpyviPAGGSEHP- 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 578830008 155 qepavIAGQGTI--ALEVLNQVPLV----DALVVPVGGGGMLAGIAITVKALKPSVKV 206
Cdd:cd06449 152 -----LGGLGYVgfVLEIAQQEEELgfkfDSIVVCSVTGSTHAGLSVGLAALGRQRRV 204
|
|
| |
