NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|630959908|ref|XP_007876362|]
View 

uncharacterized protein PFL1_00678 [Pseudozyma flocculosa PF-1]

Protein Classification

CRA domain-containing protein( domain architecture ID 10654745)

CRA domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CRA smart00757
CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, ...
 413-511 5.06e-16

CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, fungi)


:

Pssm-ID: 214806  Cd Length: 99  Bit Score: 73.48  E-value: 5.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630959908   413 ALHSALAVAQGLYSSAQKLPSYWramyLKELEQVTALLAYPDV-EHSPVRKFLHRSRKVALAEQVNSAIL-YRTGKPSQP 490
Cdd:smart00757   2 KIEEALAYARELLAPFAKEHEKF----LKELEKTMALLAYPDPtEPSPYKELLSPSQREKLAEELNSAILeLLHGKSSES 77

                           90       100
                   ....*....|....*....|.
gi 630959908   491 LIESAVRQTAFTYAGLNSDKV 511
Cdd:smart00757  78 PLEILLSAGLAALKTLLEKGG 98
 
Name Accession Description Interval E-value
CRA smart00757
CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, ...
 413-511 5.06e-16

CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, fungi)


Pssm-ID: 214806  Cd Length: 99  Bit Score: 73.48  E-value: 5.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630959908   413 ALHSALAVAQGLYSSAQKLPSYWramyLKELEQVTALLAYPDV-EHSPVRKFLHRSRKVALAEQVNSAIL-YRTGKPSQP 490
Cdd:smart00757   2 KIEEALAYARELLAPFAKEHEKF----LKELEKTMALLAYPDPtEPSPYKELLSPSQREKLAEELNSAILeLLHGKSSES 77

                           90       100
                   ....*....|....*....|.
gi 630959908   491 LIESAVRQTAFTYAGLNSDKV 511
Cdd:smart00757  78 PLEILLSAGLAALKTLLEKGG 98
CTLH pfam10607
CTLH/CRA C-terminal to LisH motif domain; RanBPM is a scaffolding protein and is important in ...
 428-498 7.22e-09

CTLH/CRA C-terminal to LisH motif domain; RanBPM is a scaffolding protein and is important in regulating cellular function in both the immune system and the nervous system. This domain is at the C-terminus of the proteins and is the binding domain for the CRA motif (for CT11-RanBPM), which is comprised of approximately 100 amino acids at the C terminal of RanBPM. It was found to be important for the interaction of RanBPM with fragile X mental retardation protein (FMRP), but its functional significance has yet to be determined. This region contains CTLH and CRA domains annotated by SMART; however, these may be a single domain, and it is refereed to as a C-terminal to LisH motif.


Pssm-ID: 402305 [Multi-domain]  Cd Length: 143  Bit Score: 54.50  E-value: 7.22e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 630959908  428 AQKLPSYWRAMYLKELEQVTALLAYPDVEH-SPVRKFLHRSRKVALAEQVNSAILYRTGKPSQPLIESAVRQ 498
Cdd:pfam10607  63 ARENLAPFNEEHLKELEKLMGLLAFPDPTDsSPYKSLLSPSRWEKLASEFNRAILKLLGLSSESPLEILLKA 134
 
Name Accession Description Interval E-value
CRA smart00757
CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, ...
 413-511 5.06e-16

CT11-RanBPM; protein-protein interaction domain present in crown eukaryotes (plants, animals, fungi)


Pssm-ID: 214806  Cd Length: 99  Bit Score: 73.48  E-value: 5.06e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 630959908   413 ALHSALAVAQGLYSSAQKLPSYWramyLKELEQVTALLAYPDV-EHSPVRKFLHRSRKVALAEQVNSAIL-YRTGKPSQP 490
Cdd:smart00757   2 KIEEALAYARELLAPFAKEHEKF----LKELEKTMALLAYPDPtEPSPYKELLSPSQREKLAEELNSAILeLLHGKSSES 77

                           90       100
                   ....*....|....*....|.
gi 630959908   491 LIESAVRQTAFTYAGLNSDKV 511
Cdd:smart00757  78 PLEILLSAGLAALKTLLEKGG 98
CTLH pfam10607
CTLH/CRA C-terminal to LisH motif domain; RanBPM is a scaffolding protein and is important in ...
 428-498 7.22e-09

CTLH/CRA C-terminal to LisH motif domain; RanBPM is a scaffolding protein and is important in regulating cellular function in both the immune system and the nervous system. This domain is at the C-terminus of the proteins and is the binding domain for the CRA motif (for CT11-RanBPM), which is comprised of approximately 100 amino acids at the C terminal of RanBPM. It was found to be important for the interaction of RanBPM with fragile X mental retardation protein (FMRP), but its functional significance has yet to be determined. This region contains CTLH and CRA domains annotated by SMART; however, these may be a single domain, and it is refereed to as a C-terminal to LisH motif.


Pssm-ID: 402305 [Multi-domain]  Cd Length: 143  Bit Score: 54.50  E-value: 7.22e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 630959908  428 AQKLPSYWRAMYLKELEQVTALLAYPDVEH-SPVRKFLHRSRKVALAEQVNSAILYRTGKPSQPLIESAVRQ 498
Cdd:pfam10607  63 ARENLAPFNEEHLKELEKLMGLLAFPDPTDsSPYKSLLSPSRWEKLASEFNRAILKLLGLSSESPLEILLKA 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH