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Conserved domains on  [gi|741966139|ref|XP_010815187|]
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myocyte-specific enhancer factor 2A isoform X5 [Bos taurus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HJURP_C super family cl13744
Holliday junction regulator protein family C-terminal repeat; Although this family is ...
 14-69 3.54e-04

Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes.


The actual alignment was detected with superfamily member pfam12347:

Pssm-ID: 463543  Cd Length: 63  Bit Score: 38.48  E-value: 3.54e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 741966139   14 ESPD---ADDYFEHSPLSEDRFSKLNEDSDFIFKR--GPPGLPPQNFSMSVTVPVTSPSAL 69
Cdd:pfam12347   3 ISPVkaiSRPRTELPGRGENRYREIKEEFDKLHQEycLSSPKQPPNTKMPVSVAVSNYRAG 63
 
Name Accession Description Interval E-value
HJURP_C pfam12347
Holliday junction regulator protein family C-terminal repeat; Although this family is ...
 14-69 3.54e-04

Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes.


Pssm-ID: 463543  Cd Length: 63  Bit Score: 38.48  E-value: 3.54e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 741966139   14 ESPD---ADDYFEHSPLSEDRFSKLNEDSDFIFKR--GPPGLPPQNFSMSVTVPVTSPSAL 69
Cdd:pfam12347   3 ISPVkaiSRPRTELPGRGENRYREIKEEFDKLHQEycLSSPKQPPNTKMPVSVAVSNYRAG 63
 
Name Accession Description Interval E-value
HJURP_C pfam12347
Holliday junction regulator protein family C-terminal repeat; Although this family is ...
 14-69 3.54e-04

Holliday junction regulator protein family C-terminal repeat; Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes.


Pssm-ID: 463543  Cd Length: 63  Bit Score: 38.48  E-value: 3.54e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 741966139   14 ESPD---ADDYFEHSPLSEDRFSKLNEDSDFIFKR--GPPGLPPQNFSMSVTVPVTSPSAL 69
Cdd:pfam12347   3 ISPVkaiSRPRTELPGRGENRYREIKEEFDKLHQEycLSSPKQPPNTKMPVSVAVSNYRAG 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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