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Conserved domains on  [gi|755498574|ref|XP_011237563|]
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filensin isoform X1 [Mus musculus]

Protein Classification

AAA family ATPase( domain architecture ID 1003843)

AAA family ATPase containing an AAA (ATPases Associated with various cellular Activities) domain, may function as an ATP-dependent endonuclease or the ATPase component of an ABC-type transporter; similar to Bacillus subtilis protein YhaN

CATH:  3.40.50.300
Gene Ontology:  GO:0005524|GO:0016887
PubMed:  15037234|18208389|16828312|18466635|15037233

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-177 4.15e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 4.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   1 MLERLNKEADEALLRNLHLQLEAQFLQADISvAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMRESGLLMQEKLFT 80
Cdd:COG4717  352 LLREAEELEEELQLEELEQEIAALLAEAGVE-DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaikhahecyDEELQLYNEQIENLRKEIEEAERSLERssydcrq 160
Cdd:COG4717  431 EEELEELEEELEELEEELEELREELAELEAELEQLEE---------DGELAELLQELEELKAELRELAEEWAA------- 494

                        170
                 ....*....|....*..
gi 755498574 161 LAVAQQTLRNELDRYHR 177
Cdd:COG4717  495 LKLALELLEEAREEYRE 511
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-177 4.15e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 4.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   1 MLERLNKEADEALLRNLHLQLEAQFLQADISvAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMRESGLLMQEKLFT 80
Cdd:COG4717  352 LLREAEELEEELQLEELEQEIAALLAEAGVE-DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaikhahecyDEELQLYNEQIENLRKEIEEAERSLERssydcrq 160
Cdd:COG4717  431 EEELEELEEELEELEEELEELREELAELEAELEQLEE---------DGELAELLQELEELKAELRELAEEWAA------- 494

                        170
                 ....*....|....*..
gi 755498574 161 LAVAQQTLRNELDRYHR 177
Cdd:COG4717  495 LKLALELLEEAREEYRE 511
PRK09039 PRK09039
peptidoglycan -binding protein;
80-227 2.80e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 2.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  80 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCR 159
Cdd:PRK09039  93 AEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARA----LAQVELLNQQIAALRRQLAALEAALDASEKRDR 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 160 Q-------------LAVAQQTlrNELDRYH-----RI---------IEIEGSRL---SSVFIETPISLITPSHGAplslg 209
Cdd:PRK09039 169 EsqakiadlgrrlnVALAQRV--QELNRYRseffgRLreilgdregIRIVGDRFvfqSEVLFPTGSAELNPEGQA----- 241

                        170
                 ....*....|....*...
gi 755498574 210 sSVKDLARAVQDITAAKP 227
Cdd:PRK09039 242 -EIAKLAAALIELAKEIP 258
Filament pfam00038
Intermediate filament protein;
5-185 3.61e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 42.60  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    5 LNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQ--TAPQVSLVTGMREsgLLMQ------- 75
Cdd:pfam00038 108 LRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVSDTQVNVEmdAARKLDLTSALAE--IRAQyeeiaak 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   76 -----EKLFTER-------------EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQI 137
Cdd:pfam00038 186 nreeaEEWYQSKleelqqaaarngdALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELI 265

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 755498574  138 ENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSR 185
Cdd:pfam00038 266 SELEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLEGEECR 313
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-174 7.75e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574     2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSL---------------VTG 66
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelkalrealdelraeLTL 814

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    67 MRESGLLMQEKL--------FTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD---EELQLYNE 135
Cdd:TIGR02168  815 LNEEAANLRERLeslerriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRS 894

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 755498574   136 QIENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDR 174
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
 
Name Accession Description Interval E-value
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-177 4.15e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 4.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   1 MLERLNKEADEALLRNLHLQLEAQFLQADISvAKDRYKKNLLEIQTYITVLQQIVQTAPQVSLVTGMRESGLLMQEKLFT 80
Cdd:COG4717  352 LLREAEELEEELQLEELEQEIAALLAEAGVE-DEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaikhahecyDEELQLYNEQIENLRKEIEEAERSLERssydcrq 160
Cdd:COG4717  431 EEELEELEEELEELEEELEELREELAELEAELEQLEE---------DGELAELLQELEELKAELRELAEEWAA------- 494

                        170
                 ....*....|....*..
gi 755498574 161 LAVAQQTLRNELDRYHR 177
Cdd:COG4717  495 LKLALELLEEAREEYRE 511
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 80-273 4.65e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 4.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  80 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHecydEELQLYNEQIENLRKEIEEAERSLERSSydcR 159
Cdd:COG4942   25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELR---A 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 160 QLAVAQQTLRNELDRYHRIIEIEGSRL---SSVFIETPISLITPSHGAP------LSLGSSVKDLARAVQDITAAKPRQK 230
Cdd:COG4942   98 ELEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAParreqaEELRADLAELAALRAELEAERAELE 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 755498574 231 ALPKSLPKRKEIIAQDKVE--ETLEDAPLKPPQEPKALQVERKAE 273
Cdd:COG4942  178 ALLAELEEERAALEALKAErqKLLARLEKELAELAAELAELQQEA 222
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 2-152 4.91e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 48.00  E-value: 4.91e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   2 LERLNKEAD--EALLRNLHLQLEAqfLQADISVAKDRYKKNLLEIQTyitVLQQIVQTAPQVSLVTGMRESGLLMQEKLF 79
Cdd:COG1579   26 LKELPAELAelEDELAALEARLEA--AKTELEDLEKEIKRLELEIEE---VEARIKKYEEQLGNVRNNKEYEALQKEIES 100

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755498574  80 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLE 152
Cdd:COG1579  101 LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1-266 6.39e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 6.39e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   1 MLERLNKEADEALLRN----LHLQLEAQFLQADISVAKDRYK------KNLLEIQTYITVLQQ-IVQTAPQVSLVTGMRE 69
Cdd:COG4717   47 LLERLEKEADELFKPQgrkpELNLKELKELEEELKEAEEKEEeyaelqEELEELEEELEELEAeLEELREELEKLEKLLQ 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  70 SGLLMQEKLFTEREVAALQNQLEEGR---EAVTHLQAQKAELQAQTTALEQAIKHAHECYD----EELQLYNEQIENLRK 142
Cdd:COG4717  127 LLPLYQELEALEAELAELPERLEELEerlEELRELEEELEELEAELAELQEELEELLEQLSlateEELQDLAEELEELQQ 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 143 EIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEgSRLSSVFIETPISLITPSHGAPLSLGSSVKDLARAVQDI 222
Cdd:COG4717  207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLK-EARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 755498574 223 TA----------AKPRQKALPKSLPKRKEIIAQDKVEETLEDAPLKPPQEPKAL 266
Cdd:COG4717  286 LAllflllarekASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEEL 339
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
79-168 1.70e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   79 FTEREVAALQNQLEEgreavthLQAQKAELQAQTTALEQAIKHAHECYDE-ELQLYN---EQIENLRKEIEEAERSLERS 154
Cdd:COG4913   285 FAQRRLELLEAELEE-------LRAELARLEAELERLEARLDALREELDElEAQIRGnggDRLEQLEREIERLERELEER 357

                          90
                  ....*....|....
gi 755498574  155 SYDCRQLAVAQQTL 168
Cdd:COG4913   358 ERRRARLEALLAAL 371
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 68-174 2.65e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 2.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  68 RESGLLMQEKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEA 147
Cdd:COG1196  225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL----ELELEEAQAEEYELLAELARL 300

                         90       100
                 ....*....|....*....|....*..
gi 755498574 148 ERSLERSSYDCRQLAVAQQTLRNELDR 174
Cdd:COG1196  301 EQDIARLEERRRELEERLEELEEELAE 327
PRK09039 PRK09039
peptidoglycan -binding protein;
80-227 2.80e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 2.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  80 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCR 159
Cdd:PRK09039  93 AEAERSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARA----LAQVELLNQQIAALRRQLAALEAALDASEKRDR 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 160 Q-------------LAVAQQTlrNELDRYH-----RI---------IEIEGSRL---SSVFIETPISLITPSHGAplslg 209
Cdd:PRK09039 169 EsqakiadlgrrlnVALAQRV--QELNRYRseffgRLreilgdregIRIVGDRFvfqSEVLFPTGSAELNPEGQA----- 241

                        170
                 ....*....|....*...
gi 755498574 210 sSVKDLARAVQDITAAKP 227
Cdd:PRK09039 242 -EIAKLAAALIELAKEIP 258
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 7-174 2.86e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.85  E-value: 2.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   7 KEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTapqvslVTGMRESGLLMQEKLF-TEREVA 85
Cdd:COG1196  225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE------LEELELELEEAQAEEYeLLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  86 ALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSydcRQLAVAQ 165
Cdd:COG1196  299 RLEQDIARLEERRRELEERLEELEEELAELEEELEEL----EEELEELEEELEEAEEELEEAEAELAEAE---EALLEAE 371


                 ....*....
gi 755498574 166 QTLRNELDR 174
Cdd:COG1196  372 AELAEAEEE 380
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2-165 6.52e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 6.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    2 LERLNKEADEallrnlhLQLEAQFLQADISVAKDRYKknllEIQTYITVLQQIVQtapqvslvtgMRESGLLMQEklfTE 81
Cdd:COG4913   612 LAALEAELAE-------LEEELAEAEERLEALEAELD----ALQERREALQRLAE----------YSWDEIDVAS---AE 667

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   82 REVAALQNQLEEGREA---VTHLQAQKAELQAQTTALEQAIKhahECYDEELQLyNEQIENLRKEIEEAERSLERSSYDC 158
Cdd:COG4913   668 REIAELEAELERLDASsddLAALEEQLEELEAELEELEEELD---ELKGEIGRL-EKELEQAEEELDELQDRLEAAEDLA 743


                  ....*..
gi 755498574  159 RQLAVAQ 165
Cdd:COG4913   744 RLELRAL 750
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
80-185 6.56e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.62  E-value: 6.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  80 TEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECY------DEELQLYNEQIENLRKEIEEAERSLER 153
Cdd:COG2433  411 EEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEErreirkDREISRLDREIERLERELEEERERIEE 490

                         90       100       110
                 ....*....|....*....|....*....|..
gi 755498574 154 ssydcrqlavaqqtLRNELDRYHRIIEIEGSR 185
Cdd:COG2433  491 --------------LKRKLERLKELWKLEHSG 508
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
20-200 1.66e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 1.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  20 QLEAQFLQADISVAKDRYKKNLLEIQtyitvLQQIVQTAPQVSLVTGMREsglLMQEKLFTEREVAALQNQLEEGREAVT 99
Cdd:COG3206  223 ELESQLAEARAELAEAEARLAALRAQ-----LGSGPDALPELLQSPVIQQ---LRAQLAELEAELAELSARYTPNHPDVI 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 100 HLQAQKAELQAQttaLEQAIKHAHECYDEELQLYNEQIENLRKEIEEAERSLERSSydcrQLAVAQQTLRNELDRYHRII 179
Cdd:COG3206  295 ALRAQIAALRAQ---LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELP----ELEAELRRLEREVEVARELY 367

                        170       180
                 ....*....|....*....|....*.
gi 755498574 180 E-----IEGSRLSSVFIETPISLITP 200
Cdd:COG3206  368 EsllqrLEEARLAEALTVGNVRVIDP 393
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
81-174 3.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD---------------EELQLYNEQIENLRKEIE 145
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDvasaereiaeleaelERLDASSDDLAALEEQLE 695

                          90       100
                  ....*....|....*....|....*....
gi 755498574  146 EAERSLERSSYDCRQLAVAQQTLRNELDR 174
Cdd:COG4913   696 ELEAELEELEEELDELKGEIGRLEKELEQ 724
Filament pfam00038
Intermediate filament protein;
5-185 3.61e-04

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 42.60  E-value: 3.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    5 LNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQ--TAPQVSLVTGMREsgLLMQ------- 75
Cdd:pfam00038 108 LRKDLDEATLARVDLEAKIESLKEELAFLKKNHEEEVRELQAQVSDTQVNVEmdAARKLDLTSALAE--IRAQyeeiaak 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   76 -----EKLFTER-------------EVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQLYNEQI 137
Cdd:pfam00038 186 nreeaEEWYQSKleelqqaaarngdALRSAKEEITELRRTIQSLEIELQSLKKQKASLERQLAETEERYELQLADYQELI 265

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 755498574  138 ENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIEIEGSR 185
Cdd:pfam00038 266 SELEAELQETRQEMARQLREYQELLNVKLALDIEIATYRKLLEGEECR 313
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2-180 4.15e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.39  E-value: 4.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQvslvtgmresgllmqeklfTE 81
Cdd:COG1196  241 LEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR-------------------LE 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  82 REVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSydcRQL 161
Cdd:COG1196  302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL----EEELEEAEEELEEAEAELAEAEEALLEAE---AEL 374

                        170
                 ....*....|....*....
gi 755498574 162 AVAQQTLRNELDRYHRIIE 180
Cdd:COG1196  375 AEAEEELEELAEELLEALR 393
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
15-154 4.19e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 42.73  E-value: 4.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  15 RNLHLQLEAqfLQADISVAKDRYK--KNLLEIQTYITVLQQIVQTApQVSLVTGMREsgLLMQEKLFTEREVAalQNQLE 92
Cdd:COG1566   79 TDLQAALAQ--AEAQLAAAEAQLArlEAELGAEAEIAAAEAQLAAA-QAQLDLAQRE--LERYQALYKKGAVS--QQELD 151

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755498574  93 EGREAVTHLQAQKAELQAQTTALEQAIKhahecYDEELQLYNEQIENLRKEIEEAERSLERS 154
Cdd:COG1566  152 EARAALDAAQAQLEAAQAQLAQAQAGLR-----EEEELAAAQAQVAQAEAALAQAELNLART 208
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-174 7.75e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 7.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574     2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTAPQVSL---------------VTG 66
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelkalrealdelraeLTL 814

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    67 MRESGLLMQEKL--------FTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD---EELQLYNE 135
Cdd:TIGR02168  815 LNEEAANLRERLeslerriaATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAsleEALALLRS 894

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 755498574   136 QIENLRKEIEEAERSLERSSYDCRQLAVAQQTLRNELDR 174
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
81-180 8.52e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQaIKHAHecydEELQLYNEQIEN---LRKEIEEAE---RSLERS 154
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQE-RREAL----QRLAEYSWDEIDvasAEREIAELEaelERLDAS 683

                          90       100
                  ....*....|....*....|....*.
gi 755498574  155 SYDCRQLAVAQQTLRNELDRYHRIIE 180
Cdd:COG4913   684 SDDLAALEEQLEELEAELEELEEELD 709
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2-180 1.19e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574     2 LERLNKEADEALLRNLHLQLEAQFLQADISVAKDR----------YKKNLLEIQTYITVLQQIVQTA------PQVSLVT 65
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEvseleeeieeLQKELYALANEISRLEQQKQILrerlanLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    66 GMRESGLLMQEKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYD----------EELQLYNE 135
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLEtlrskvaqleLQIASLNN 400

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 755498574   136 QIENLRKEIEEAERSLERssYDCRQLAVAQQTLRNELDRYHRIIE 180
Cdd:TIGR02168  401 EIERLEARLERLEDRRER--LQQEIEELLKKLEEAELKELQAELE 443
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
24-186 1.20e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  24 QFLQADISVAKDRYKKNLLEIQTYITVLQQIVQTApQVSLVTGMRESGLLMqeklfTEREVAALQNQLEEGREAVTHLQA 103
Cdd:COG3206  160 AYLEQNLELRREEARKALEFLEEQLPELRKELEEA-EAALEEFRQKNGLVD-----LSEEAKLLLQQLSELESQLAEARA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574 104 QKAELQAQTTALEQAIKHAHECYDEELQlyNEQIENLRKEIEEAERSL--ERSSYDCRQLAVaqQTLRNELDRYHRIIEI 181
Cdd:COG3206  234 ELAEAEARLAALRAQLGSGPDALPELLQ--SPVIQQLRAQLAELEAELaeLSARYTPNHPDV--IALRAQIAALRAQLQQ 309


                 ....*
gi 755498574 182 EGSRL 186
Cdd:COG3206  310 EAQRI 314
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 68-180 1.60e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    68 RESGLLMQEKLFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHE----CYDEELQLYNEQIENLRKE 143
Cdd:TIGR02169  223 YEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAE 302

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 755498574   144 IEEAERSLERSSYDCRQLAVAQQTLRNELDRYHRIIE 180
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIE 339
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 82-180 1.94e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.08  E-value: 1.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  82 REVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQL 161
Cdd:COG1196  232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL----RLELEELELELEEAQAEEYELLAELARLEQDIARL 307

                         90
                 ....*....|....*....
gi 755498574 162 AVAQQTLRNELDRYHRIIE 180
Cdd:COG1196  308 EERRRELEERLEELEEELA 326
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 78-186 4.08e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 40.04  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574    78 LFTEREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYD 157
Cdd:TIGR02168  673 LERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQL----RKELEELSRQISALRKDLARLEAEVEQLEER 748

                           90       100
                   ....*....|....*....|....*....
gi 755498574   158 CRQLAVAQQTLRNELDRYHRIIEIEGSRL 186
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEEL 777
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 82-170 4.82e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 39.94  E-value: 4.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   82 REVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDEELQlynEQIENLRKEIE---EAERSLERSSYDC 158
Cdd:COG3096   843 QRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLA---DRLEELREELDaaqEAQAFIQQHGKAL 919

                          90
                  ....*....|..
gi 755498574  159 RQLAVAQQTLRN 170
Cdd:COG3096   920 AQLEPLVAVLQS 931
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 81-167 4.94e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 39.43  E-value: 4.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574  81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAhecyDEELQLYNEQIENLRKEIEEAERSLERSSYDCRQ 160
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90


                 ....*..
gi 755498574 161 LAVAQQT 167
Cdd:COG3883   91 RARALYR 97
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
81-177 7.36e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.13  E-value: 7.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755498574   81 EREVAALQNQLEEGREAVTHLQAQKAELQAQTTALEQAIKHAHECYDE-------------ELQLYNEQIENLRKEIEEA 147
Cdd:COG4913   691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlarlelrallEERFAAALGDAVERELREN 770

                          90       100       110
                  ....*....|....*....|....*....|.
gi 755498574  148 -ERSLERSSydcRQLAVAQQTLRNELDRYHR 177
Cdd:COG4913   771 lEERIDALR---ARLNRAEEELERAMRAFNR 798
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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