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Conserved domains on  [gi|755527302|ref|XP_011246818|]
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tetratricopeptide repeat protein 29 isoform X1 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 234-381 3.33e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 234 VRTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGL 313
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALEK------ALKLDPDC 177

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302 314 GRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQAF 381
Cdd:COG2956  178 ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP------RLAELYEKLGDPEEALELLRKAL 239
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 234-381 3.33e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 234 VRTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGL 313
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALEK------ALKLDPDC 177

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302 314 GRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQAF 381
Cdd:COG2956  178 ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP------RLAELYEKLGDPEEALELLRKAL 239
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 245-380 9.24e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 9.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302  245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEIstsLDDDHglgRAYEAIAKAL 324
Cdd:TIGR02917 272 FQKKNYEDARETLQDALKSAPE------YLPALLLAGASEYQLGNLEQAYQYLNQILKY---APNSH---QARRLLASIQ 339

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755527302  325 QSQGETTEAINYLEKFVTIARNNLQSLdmiracTMLGDIYNEKGQYSKASEYFQQA 380
Cdd:TIGR02917 340 LRLGRVDEAIATLSPALGLDPDDPAAL------SLLGEAYLALGDFEKAAEYLAKA 389
TPR_12 pfam13424
Tetratricopeptide repeat;
315-380 1.67e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.37  E-value: 1.67e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302  315 RAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDMIRACTM--LGDIYNEKGQYSKASEYFQQA 380
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLlnLGRLYLELGRYEEALELLERA 71
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 234-381 3.33e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 3.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 234 VRTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGL 313
Cdd:COG2956  110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALEK------ALKLDPDC 177

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302 314 GRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQAF 381
Cdd:COG2956  178 ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALP------RLAELYEKLGDPEEALELLRKAL 239
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 165-380 5.56e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 5.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 165 RCFNIAQLIKADGGKKEAEAESHMGLLFEEEGELLKAAEHYEAFHEL----THGRLWKDGTGQLLNLVACESLVRTYRLL 240
Cdd:COG3914    5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALaeaaAAALLALAAGEAAAAAAALLLLAALLELA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 241 SDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGLGRAYEAI 320
Cdd:COG3914   85 ALLLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRR------ALALNPDFAEAYLNL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 321 AKALQSQGETTEAINYLEKFVTIARNNLQsldmirACTMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG3914  153 GEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQDLGRLEEAIAAYRRA 206
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 245-380 3.19e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 3.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYseistsLDDDHGLGRAYEAIAKAL 324
Cdd:COG2956   19 LLNGQPDKAIDLLEEALELDPE------TVEAHLALGNLYRRRGEYDRAIRIHQKL------LERDPDRAEALLELAQDY 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 755527302 325 QSQGETTEAINYLEKFVTIARNNLQSLdmiracTMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG2956   87 LKAGLLDRAEELLEKLLELDPDDAEAL------RLLAEIYEQEGDWEKAIEVLERL 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
233-380 6.12e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 56.55  E-value: 6.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 233 LVRTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHG 312
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGRYEEALADYEQ------ALELDPD 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302 313 LGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG0457   75 DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALY------NLGLALLELGRYDEAIEAYERA 136
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 200-393 1.16e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.19  E-value: 1.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 200 KAAEHYEAFHEL------THGRL---------WKDGTGQLLNLVA-CESLVRTYRLLSDRMLENKDYKQAIKILIKASEI 263
Cdd:COG2956   26 KAIDLLEEALELdpetveAHLALgnlyrrrgeYDRAIRIHQKLLErDPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 264 AREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEISTsldddhGLGRAYEAIAKALQSQGETTEAINYLEKFVTI 343
Cdd:COG2956  106 DPD------DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP------ENAHAYCELAELYLEQGDYDEAIEALEKALKL 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 755527302 344 ARNNlqsldmIRACTMLGDIYNEKGQYSKASEYFQQAFSTAMELMKTALM 393
Cdd:COG2956  174 DPDC------ARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPR 217
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 245-380 8.43e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.26  E-value: 8.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGLGRAYEAIAKAL 324
Cdd:COG4783   15 LLAGDYDEAEALLEKALELDPD------NPEAFALLGEILLQLGDLDEAIVLLHE------ALELDPDEPEARLNLGLAL 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 755527302 325 QSQGETTEAINYLEKFVTIARNNLQSLDMiractmLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG4783   83 LKAGDYDEALALLEKALKLDPEHPEAYLR------LARAYRALGRPDEAIAALEKA 132
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 278-384 1.08e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.11  E-value: 1.08e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 278 YYLGLAHLASGEYETALTVLNRYSEISTSLDDdhglgrAYEAIAKALQSQGETTEAINYLEKfvTIARNNlqslDMIRAC 357
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVE------AHLALGNLYRRRGEYDRAIRIHQK--LLERDP----DRAEAL 79

                         90       100
                 ....*....|....*....|....*..
gi 755527302 358 TMLGDIYNEKGQYSKASEYFQQAFSTA 384
Cdd:COG2956   80 LELAQDYLKAGLLDRAEELLEKLLELD 106
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
235-380 1.28e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 235 RTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEIstslddDHGLG 314
Cdd:COG0457   43 EALYNLGLAYLRLGRYEEALADYEQALELDPD------DAEALNNLGLALQALGRYEEALEDYDKALEL------DPDDA 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 755527302 315 RAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG0457  111 EALYNLGLALLELGRYDEAIEAYERALELDPDDADALY------NLGIALEKLGRYEEALELLEKL 170
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 274-384 3.76e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 3.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 274 GEASYYLGLAHLASGEYETALTVLNRyseiSTSLDDDHGlgRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLdm 353
Cdd:COG4235   17 AEGWLLLGRAYLRLGRYDEALAAYEK----ALRLDPDNA--DALLDLAEALLAAGDTEEAEELLERALALDPDNPEAL-- 88

                         90       100       110
                 ....*....|....*....|....*....|.
gi 755527302 354 iracTMLGDIYNEKGQYSKASEYFQQAFSTA 384
Cdd:COG4235   89 ----YLLGLAAFQQGDYAEAIAAWQKLLALL 115
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 275-380 4.12e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 4.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 275 EASYYLGLAHLASGEYETALTVLNRYseistsLDDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmi 354
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKA------LELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARL-- 76

                         90       100
                 ....*....|....*....|....*.
gi 755527302 355 ractMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG4783   77 ----NLGLALLKAGDYDEALALLEKA 98
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 245-380 9.24e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 9.24e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302  245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEIstsLDDDHglgRAYEAIAKAL 324
Cdd:TIGR02917 272 FQKKNYEDARETLQDALKSAPE------YLPALLLAGASEYQLGNLEQAYQYLNQILKY---APNSH---QARRLLASIQ 339

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 755527302  325 QSQGETTEAINYLEKFVTIARNNLQSLdmiracTMLGDIYNEKGQYSKASEYFQQA 380
Cdd:TIGR02917 340 LRLGRVDEAIATLSPALGLDPDDPAAL------SLLGEAYLALGDFEKAAEYLAKA 389
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 239-382 2.03e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 2.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302  239 LLSDRMLENKDYKQAIKILIKASEIAREGNDRSMEgeasyyLGLAHLASGEYETALtvlnrySEISTSLDDDHGLGRAYE 318
Cdd:TIGR02917 368 LLGEAYLALGDFEKAAEYLAKATELDPENAAARTQ------LGISKLSQGDPSEAI------ADLETAAQLDPELGRADL 435

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755527302  319 AIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmiractMLGDIYNEKGQYSKASEYFQQAFS 382
Cdd:TIGR02917 436 LLILSYLRSGQFDKALAAAKKLEKKQPDNASLHN------LLGAIYLGKGDLAKAREAFEKALS 493
COG3899 COG3899
Predicted ATPase [General function prediction only];
231-411 2.09e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 47.16  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302  231 ESLVRTYRLLSDRMLENKDYKQAIKILIKASEIAREGNDRSMEGEASYYLGLAHLASGEYETALTVLNR-------YSEI 303
Cdd:COG3899   702 DRAARLLLRAARRALARGAYAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERalaaralAALA 781

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302  304 STSLDDDHGLGRAYEAIAKALqsQGETTEAINYLEKFVTIARNNLQSLDMIRACTMLGDIYNEKGQYSKASEYFQQAFST 383
Cdd:COG3899   782 ALRHGNPPASARAYANLGLLL--LGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEA 859

                         170       180
                  ....*....|....*....|....*...
gi 755527302  384 AMELMKTALMDETKVHYGIARAHQMMLA 411
Cdd:COG3899   860 GLETGDAALALLALAAAAAAAAAAAALA 887
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 245-341 7.64e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 7.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 245 LENKDYKQAIKILikaSEIAREGNDRSMEGEASYYLGLAHLASGEYETALTVLNRYSEIStslDDDHGLGRAYEAIAKAL 324
Cdd:COG1729    4 LKAGDYDEAIAAF---KAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY---PDSPKAPDALLKLGLSY 77

                         90
                 ....*....|....*..
gi 755527302 325 QSQGETTEAINYLEKFV 341
Cdd:COG1729   78 LELGDYDKARATLEELI 94
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 282-379 7.86e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.90  E-value: 7.86e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 282 LAHLASGEYETALTVLNRYSEistSLDDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDmirACTMLG 361
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLK---RYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPD---ALLKLG 74

                         90
                 ....*....|....*...
gi 755527302 362 DIYNEKGQYSKASEYFQQ 379
Cdd:COG1729   75 LSYLELGDYDKARATLEE 92
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 237-347 8.70e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.49  E-value: 8.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 237 YRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEistsLDDDHglGRA 316
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEALELDPD------EPEARLNLGLALLKAGDYDEALALLEKALK----LDPEH--PEA 108

                         90       100       110
                 ....*....|....*....|....*....|.
gi 755527302 317 YEAIAKALQSQGETTEAINYLEKFVTIARNN 347
Cdd:COG4783  109 YLRLARAYRALGRPDEAIAALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
245-349 3.02e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.77  E-value: 3.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALtvlnrysEISTSLDDDHGLGRAYEAIAKAL 324
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAI-------ALEKALKLDPNNAEALLNLAELL 69

                         90       100
                 ....*....|....*....|....*
gi 755527302 325 QSQGETTEAINYLEKFVTIARNNLQ 349
Cdd:COG3063   70 LELGDYDEALAYLERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 234-339 4.23e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 4.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 234 VRTYRLLSDRMLENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEISTSLDddhgl 313
Cdd:COG2956  178 ARALLLLAELYLEQGDYEEAIAALERALEQDPD------YLPALPRLAELYEKLGDPEEALELLRKALELDPSDD----- 246

                         90       100
                 ....*....|....*....|....*.
gi 755527302 314 grAYEAIAKALQSQGETTEAINYLEK 339
Cdd:COG2956  247 --LLLALADLLERKEGLEAALALLER 270
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
307-380 7.62e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 41.15  E-value: 7.62e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 755527302 307 LDDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLdmiracTMLGDIYNEKGQYSKASEYFQQA 380
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEAL------YNLGLAYLRLGRYEEALADYEQA 68
TPR_12 pfam13424
Tetratricopeptide repeat;
315-380 1.67e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.37  E-value: 1.67e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 755527302  315 RAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDMIRACTM--LGDIYNEKGQYSKASEYFQQA 380
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLlnLGRLYLELGRYEEALELLERA 71
TPR_12 pfam13424
Tetratricopeptide repeat;
232-306 1.79e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.98  E-value: 1.79e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 755527302  232 SLVRTYRLLSDRMLENKDYKQAIKILIKASEIARE--GNDRSMEGEASYYLGLAHLASGEYETALTVLNRYSEISTS 306
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRllGPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 234-347 1.82e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 1.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 234 VRTYRLLSDRMLENKDYKQAIKILIKAseIAREGNDrsmeGEASYYLGLAHLASGEYETALTVLNRyseistSLDDDHGL 313
Cdd:COG4235   17 AEGWLLLGRAYLRLGRYDEALAAYEKA--LRLDPDN----ADALLDLAEALLAAGDTEEAEELLER------ALALDPDN 84

                         90       100       110
                 ....*....|....*....|....*....|....
gi 755527302 314 GRAYEAIAKALQSQGETTEAINYLEKFVTIARNN 347
Cdd:COG4235   85 PEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
283-389 1.97e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 1.97e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 283 AHLASGEYETALTVLNRyseistSLDDDHGLGRAYEAIAKALQSQGETTEAINYlEKFVTIARNNLQSLdmiracTMLGD 362
Cdd:COG3063    1 LYLKLGDLEEAEEYYEK------ALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEAL------LNLAE 67

                         90       100
                 ....*....|....*....|....*..
gi 755527302 363 IYNEKGQYSKASEYFQQAFSTAMELMK 389
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDPSALR 94
TPR_12 pfam13424
Tetratricopeptide repeat;
276-346 3.32e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.21  E-value: 3.32e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 755527302  276 ASYYLGLAHLASGEYETALTVLNRYSEISTSL--DDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARN 346
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 245-339 3.42e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.02  E-value: 3.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755527302 245 LENKDYKQAIKILIKASEIAREgndrsmEGEASYYLGLAHLASGEYETALTVLNRYSEIstslddDHGLGRAYEAIAKAL 324
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPN------NPELYYNLALLYSRSGDKDEAKEYYEKALAL------SPDNPNAYSNLAALL 132

                         90
                 ....*....|....*
gi 755527302 325 QSQGETTEAINYLEK 339
Cdd:COG5010  133 LSLGQDDEAKAALQR 147
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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