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Conserved domains on  [gi|768001990|ref|XP_011526228|]
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mitochondrial carrier protein SCaMC-3L isoform X1 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 23-304 3.27e-26

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 104.85  E-value: 3.27e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  23 DNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN--------FTNLLGGLQSMVQEGGFRSLWRGNGINVLK 94
Cdd:PTZ00169   2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEiksgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  95 IAPEYAIKFSVFEQCKNYFCGIQGSPPFQE----RLLAGSLAVAISQTLINPMEVLKTRLT--LRRTG--QYKGLLDCAR 166
Cdd:PTZ00169  82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990 167 QILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKsgrDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRM 246
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRM 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768001990 247 QAQDTVEGSNPTMRG----VLQRILAQQGWLGLYRGMTPTLLKVLpAGGISYVVYEAMKKTL 304
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTgtldCWKKILKNEGLGGFFKGAWANVLRGA-GGALVLVFYDELQKLL 299
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 23-304 3.27e-26

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 104.85  E-value: 3.27e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  23 DNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN--------FTNLLGGLQSMVQEGGFRSLWRGNGINVLK 94
Cdd:PTZ00169   2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEiksgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  95 IAPEYAIKFSVFEQCKNYFCGIQGSPPFQE----RLLAGSLAVAISQTLINPMEVLKTRLT--LRRTG--QYKGLLDCAR 166
Cdd:PTZ00169  82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990 167 QILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKsgrDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRM 246
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRM 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768001990 247 QAQDTVEGSNPTMRG----VLQRILAQQGWLGLYRGMTPTLLKVLpAGGISYVVYEAMKKTL 304
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTgtldCWKKILKNEGLGGFFKGAWANVLRGA-GGALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
118-210 3.65e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 91.18  E-value: 3.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  118 GSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRT---GQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACT 194
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 768001990  195 DLAVYEMLQCFWVKSG 210
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 23-304 3.27e-26

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 104.85  E-value: 3.27e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  23 DNKEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTN--------FTNLLGGLQSMVQEGGFRSLWRGNGINVLK 94
Cdd:PTZ00169   2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEiksgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  95 IAPEYAIKFSVFEQCKNYFCGIQGSPPFQE----RLLAGSLAVAISQTLINPMEVLKTRLT--LRRTG--QYKGLLDCAR 166
Cdd:PTZ00169  82 YFPTQAFNFAFKDYFKNMFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLM 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990 167 QILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKsgrDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRM 246
Cdd:PTZ00169 162 KISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLFG---NDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRM 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768001990 247 QAQDTVEGSNPTMRG----VLQRILAQQGWLGLYRGMTPTLLKVLpAGGISYVVYEAMKKTL 304
Cdd:PTZ00169 239 MMMSGRKAKSEIQYTgtldCWKKILKNEGLGGFFKGAWANVLRGA-GGALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
118-210 3.65e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 91.18  E-value: 3.65e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  118 GSPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRT---GQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACT 194
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*.
gi 768001990  195 DLAVYEMLQCFWVKSG 210
Cdd:pfam00153  81 YFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
28-113 7.58e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 90.41  E-value: 7.58e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990   28 LWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYS--SKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSV 105
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGgsGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84


                  ....*...
gi 768001990  106 FEQCKNYF 113
Cdd:pfam00153  85 YETLKRLL 92
Mito_carr pfam00153
Mitochondrial carrier protein;
214-305 8.99e-19

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 79.62  E-value: 8.99e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990  214 GDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTV-EGSNPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGI 292
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|...
gi 768001990  293 SYVVYEAMKKTLG 305
Cdd:pfam00153  81 YFGTYETLKRLLL 93
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 126-302 1.32e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 42.60  E-value: 1.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990 126 LLAGSLAVAISQTLINPMEVLKTRLTlrrtgqykglldcARQILQREGTRALYRGYLPNMLGIIPYACtdlavyeMLQCF 205
Cdd:PTZ00168   7 LVTGALSGVIVDAVLYPIDSIKTNIQ-------------AKKSFSFSDIKKLYSGILPTLVGTVPASA-------FFYCF 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768001990 206 WVKSGRDMGDPSGLVSLSSVTL-STTCGQMAS----YPLTLVRTRMQaqdtVEGSNPTMRGVLQriLAQQGWLGLYRGMT 280
Cdd:PTZ00168  67 YELSKKLLTEYRENISKTNLYLiSTSIAEITAcivrLPFEIVKQNMQ----VSGNISVLKTIYE--ITQREGLPSFLGKS 140

                        170       180
                 ....*....|....*....|....
gi 768001990 281 PTLLKV--LPAGGISYVVYEAMKK 302
Cdd:PTZ00168 141 YFVMIVreIPFDCIQYFLWETLKE 164
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 237-304 5.46e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 37.60  E-value: 5.46e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768001990 237 YPLTLVRTRMQAQDTVEGSNPTMrgvlqrilaqqgwlgLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 304
Cdd:PTZ00168  22 YPIDSIKTNIQAKKSFSFSDIKK---------------LYSGILPTLVGTVPASAFFYCFYELSKKLL 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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