|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.34e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
:
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.34e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016675 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 super family |
cl26621 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
525-843 |
2.28e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
The actual alignment was detected with superfamily member pfam09606:
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.72 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 525 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 604
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 605 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 677
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 678 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 756
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 757 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 836
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 768016675 837 HVQAMQG 843
Cdd:pfam09606 361 GANPMQR 367
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1061-1307 |
3.24e-06 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1061 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1140
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1141 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1209
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1210 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1289
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016675 1290 qAPSNLTMNPSNFATPQT 1307
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
190-549 |
1.01e-04 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.63 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 190 PPGGNVS----SSMMAPGPNPELQPRTPRPASQSDAMDPLlsglhiqqqshpsGSLAPPHHPMQPVSvnrqmnPANFPQL 265
Cdd:PHA03247 2656 PAPGRVSrprrARRLGRAAQASSPPQRPRRRAARPTVGSL-------------TSLADPPPPPPTPE------PAPHALV 2716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 266 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTA 345
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 346 NQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP-GQFTAPqmkslqGGPSRVPTPLQ 424
Cdd:PHA03247 2797 SLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlGGSVAP------GGDVRRRPPSR 2869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 425 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQPVSSPGRNPMVQQGNVPPnfmvmqqqPPNQ 504
Cdd:PHA03247 2870 SPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPPQPQPQPPPPPQPQPPPP--------PPPR 2938
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 768016675 505 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 549
Cdd:PHA03247 2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.34e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.34e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016675 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
525-843 |
2.28e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.72 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 525 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 604
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 605 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 677
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 678 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 756
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 757 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 836
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 768016675 837 HVQAMQG 843
Cdd:pfam09606 361 GANPMQR 367
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1061-1307 |
3.24e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1061 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1140
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1141 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1209
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1210 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1289
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016675 1290 qAPSNLTMNPSNFATPQT 1307
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
617-760 |
6.42e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 617 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 695
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016675 696 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 760
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
190-549 |
1.01e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.63 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 190 PPGGNVS----SSMMAPGPNPELQPRTPRPASQSDAMDPLlsglhiqqqshpsGSLAPPHHPMQPVSvnrqmnPANFPQL 265
Cdd:PHA03247 2656 PAPGRVSrprrARRLGRAAQASSPPQRPRRRAARPTVGSL-------------TSLADPPPPPPTPE------PAPHALV 2716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 266 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTA 345
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 346 NQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP-GQFTAPqmkslqGGPSRVPTPLQ 424
Cdd:PHA03247 2797 SLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlGGSVAP------GGDVRRRPPSR 2869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 425 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQPVSSPGRNPMVQQGNVPPnfmvmqqqPPNQ 504
Cdd:PHA03247 2870 SPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPPQPQPQPPPPPQPQPPPP--------PPPR 2938
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 768016675 505 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 549
Cdd:PHA03247 2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1112-1407 |
1.07e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1112 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1183
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1184 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1257
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1258 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1336
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768016675 1337 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1407
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-195 |
2.34e-59 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 200.73 E-value: 2.34e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768016675 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIFflgiiRMNNPATVMIPPGGNV 195
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLI-----SDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
525-843 |
2.28e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.72 E-value: 2.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 525 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 604
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 605 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 677
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 678 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 756
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 757 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 836
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 768016675 837 HVQAMQG 843
Cdd:pfam09606 361 GANPMQR 367
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
277-753 |
2.16e-06 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 53.09 E-value: 2.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 277 QQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAptqvPVPPGwNQLPSGALQPPPAQGSLGTMTANQGWKK---AP 353
Cdd:pfam09606 64 QGGQGNGGMGGGQQGMPDPINALQNLAGQGTRPQMMG----PMGPG-PGGPMGQQMGGPGTASNLLASLGRPQMPmggAG 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 354 LPGPMQQQLQARPSLATvqtpsHPPPPYPFGSQQASQAHTNFPQMSnPGQFTAPQMKSLQGGPSRVPTPLQ--------- 424
Cdd:pfam09606 139 FPSQMSRVGRMQPGGQA-----GGMMQPSSGQPGSGTPNQMGPNGG-PGQGQAGGMNGGQQGPMGGQMPPQmgvpgmpgp 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 425 ---QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMgpRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMvmqqqp 501
Cdd:pfam09606 213 adaGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQ--QQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPM------ 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 502 pnqgpqslhPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMqvshGP 581
Cdd:pfam09606 285 ---------GPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHL----ET 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 582 PNMMQPSLMGIHGnMNNQQAGTSGVPQVnlSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLM 661
Cdd:pfam09606 352 WNPGNFGGLGANP-MQRGQPGMMSSPSP--VPGQQVRQVTPNQFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSPALIPS 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 662 PQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnv 741
Cdd:pfam09606 429 PSPQMSQQPAQQRTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYREKYRQLTKYIEPLKRMIAKMENDPGDIDKMNK--- 505
|
490
....*....|..
gi 768016675 742 MPGPAQIMRGPT 753
Cdd:pfam09606 506 MKRLLEILSNPS 517
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
617-787 |
3.13e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 52.35 E-value: 3.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 617 QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQnpmilsraQLMPQGQMMVNPPSQNLGPSPQRmtppkqmLSQQGPQM 696
Cdd:pfam09770 209 KPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQ--------QQQPQQQPQQPQQHPGQGHPVTI-------LQRPQSPQ 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 697 MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnvMPGPAQIMRGPTPNMQgnmvqftGQMSGQMLPQQG 776
Cdd:pfam09770 274 PDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVG---YPQNPQPGVQPAPAHQ-------AHRQQGSFGRQA 343
|
170
....*....|.
gi 768016675 777 PVNNSPSQVMG 787
Cdd:pfam09770 344 PIITHPQQLAQ 354
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1061-1307 |
3.24e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1061 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1140
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1141 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1209
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1210 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1289
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 768016675 1290 qAPSNLTMNPSNFATPQT 1307
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
460-659 |
2.88e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 49.26 E-value: 2.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 460 PRPPQNNPLPQGFQQPVSSPGRN---------PMVQQGNVPPNfmvmQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN 530
Cdd:pfam09770 170 AAAPAPAPQPAAQPASLPAPSRKmmsleeveaAMRAQAKKPAQ----QPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 531 PNFMQGQVPSTtattPGNSGAPQ-LQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPslMGIHGNMNNQQAGTSGVPQv 609
Cdd:pfam09770 246 PQQQPQQPQQH----PGQGHPVTiLQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQP--TQILQNPNRLSAARVGYPQ- 318
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 768016675 610 nlsNMQGQPQQGPPSQlmgmHQQIVPSQGQMVQQQgtLNPQNPMILSRAQ 659
Cdd:pfam09770 319 ---NPQPGVQPAPAHQ----AHRQQGSFGRQAPII--THPQQLAQLSEEE 359
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1090-1564 |
3.58e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1090 PASVPPSPDkQRMPMPVNTPlgsnsrkmvyqeSPQNPSSSPLAEMASLPEASGSeaPSVPGGPNNMPSHVV----LPQNQ 1165
Cdd:PHA03247 2557 PAAPPAAPD-RSVPPPRPAP------------RPSEPAVTSRARRPDAPPQSAR--PRAPVDDRGDPRGPAppspLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1166 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1245
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1246 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1325
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAAR----QASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1326 TKRASPSNSRRSSPGSSRKTTPS---PGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLN 1402
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSpwdPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1403 PQNSTVSVAAVGGVVEDNKESLNVPQDSdcqnsqsrkeqvnIELKAVPAQEVKMVVPEDQSKKDGQPSDPNK--LPSVEE 1480
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR-------------LARPAVSRSTESFALPPDQPERPPQPQAPPPpqPQPQPP 2924
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1481 NKNLVSPAMREAPTSLSQL---LDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHS 1557
Cdd:PHA03247 2925 PPPQPQPPPPPPPRPQPPLaptTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRV 3004
|
....*..
gi 768016675 1558 NELCSSL 1564
Cdd:PHA03247 3005 SSWASSL 3011
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
617-760 |
6.42e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 617 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 695
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768016675 696 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 760
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
190-549 |
1.01e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 47.63 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 190 PPGGNVS----SSMMAPGPNPELQPRTPRPASQSDAMDPLlsglhiqqqshpsGSLAPPHHPMQPVSvnrqmnPANFPQL 265
Cdd:PHA03247 2656 PAPGRVSrprrARRLGRAAQASSPPQRPRRRAARPTVGSL-------------TSLADPPPPPPTPE------PAPHALV 2716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 266 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTA 345
Cdd:PHA03247 2717 SATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 346 NQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNP-GQFTAPqmkslqGGPSRVPTPLQ 424
Cdd:PHA03247 2797 SLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlGGSVAP------GGDVRRRPPSR 2869
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 425 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQPVSSPGRNPMVQQGNVPPnfmvmqqqPPNQ 504
Cdd:PHA03247 2870 SPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPPQPQPQPPPPPQPQPPPP--------PPPR 2938
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 768016675 505 GPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 549
Cdd:PHA03247 2939 PQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
624-775 |
1.77e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 46.72 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 624 SQLMGMHQQIVPSQGQMVQqqgtLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMtPPKQMLSQQGPQMMAPhnqm 703
Cdd:TIGR01628 369 AHLQDQFMQLQPRMRQLPM----GSPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMP-TPMGPGGPLRPNGLAP---- 439
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 768016675 704 MGPQGQVLLQQNPMIEQimtNQMQGNKQQFNTQNQSNVMPGPAQimrGPTPNMQGNMvQFTGQMSGQMLPQQ 775
Cdd:TIGR01628 440 MNAVRAPSRNAQNAAQK---PPMQPVMYPPNYQSLPLSQDLPQP---QSTASQGGQN-KKLAQVLASATPQM 504
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
934-1495 |
2.08e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 2.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 934 DLNTPDTRPAgleeadqpPLPGEQGINLDNSGPKLPEFSNRP--PGYPS-QPVEQRPLQQMPPQLMQHVAPPPQPPQQQP 1010
Cdd:PHA03247 2565 DRSVPPPRPA--------PRPSEPAVTSRARRPDAPPQSARPraPVDDRgDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN 2636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1011 QPQLPQQQQPPPPSQPQSQQQqqqqqqmmmmlmmqqdPKSVRLP--VSQNVHPPRGPLNPDSQRMPMQQSGSVPVmVSLQ 1088
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPA----------------PGRVSRPrrARRLGRAAQASSPPQRPRRRAARPTVGSL-TSLA 2699
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1089 GPASVPPSPDKQRMPMPVNTPL--GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA-PSVPGGPNNmPSHVVLPQNQ 1165
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLppGPAAARQASPALPAAPAPPAVPAGPATPGGPARPArPPTTAGPPA-PAPPAAPAAG 2778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1166 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVaAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1245
Cdd:PHA03247 2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1246 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqqglnpTTLKAIGQAPSNLTMNPSNFATPQTHKLDsvvvnSGKQSNSGA 1325
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---------LARPAVSRSTESFALPPDQPERPPQPQAP-----PPPQPQPQP 2923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1326 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQ-NVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQ 1404
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPgRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1405 NSTVSVAAVGGVVEDN-----KESLNVPQDSDCQNSQSRKEQVNIELkavpaqevkmvvpeDQSKKDGQPSDPNKLPSVE 1479
Cdd:PHA03247 3004 VSSWASSLALHEETDPppvslKQTLWPPDDTEDSDADSLFDSDSERS--------------DLEALDPLPPEPHDPFAHE 3069
|
570
....*....|....*.
gi 768016675 1480 ENKNLVSPAMREAPTS 1495
Cdd:PHA03247 3070 PDPATPEAGARESPSS 3085
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1112-1407 |
1.07e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1112 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1183
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1184 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1257
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1258 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1336
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768016675 1337 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1407
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
204-575 |
1.71e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 204 PNPELQPRTPRPASQSDAMDPllsGLHIQQ--------------QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQ 269
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRARRP---DAPPQSarprapvddrgdprGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPT 2645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 270 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV-----PPGWNQLPSGAlqPPPAQGSLGTMT 344
Cdd:PHA03247 2646 VPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLtsladPPPPPPTPEPA--PHALVSATPLPP 2723
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 345 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ 424
Cdd:PHA03247 2724 GPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 425 QPHLTNKSPASSPSSFQQGSPAS----SPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV-------PPN 493
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAASPAGplppPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAkpaaparPPV 2883
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 494 FMVMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPqLQANQNVQHAGGQGAGPPQN 573
Cdd:PHA03247 2884 RRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP-LAPTTDPAGAGEPSGAVPQP 2962
|
..
gi 768016675 574 QM 575
Cdd:PHA03247 2963 WL 2964
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
1085-1299 |
2.67e-03 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 42.11 E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1085 VSLQGPASVPPSPDKQRMPMPVNTPLGS--NSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLP 1162
Cdd:pfam15279 91 ESVSPGPSSSASPSSSPTSSNSSKPLISvaSSSKLLAPKPHEPPSLPPPPLPPKKGRRHRPGLHPPLGRPPGSPPMSMTP 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768016675 1163 QNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHhfPNVAAPTQTSRPKTPNRASPRPYYPQT-PNNRPP-----S 1236
Cdd:pfam15279 171 RGLLGKPQQHPPPSPLPAFMEPSSMPPPFLRPPPSIPQ--PNSPLSNPMLPGIGPPPKPPRNLGPPSnPMHRPPfsphhP 248
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768016675 1237 TEPSEISLSPERLNASIAGLFPPQINIPLPPrpnLNRGFDQQGLNPTTLKAIGQAPSNLTMNP 1299
Cdd:pfam15279 249 PPPPTPPGPPPGLPPPPPRGFTPPFGPPFPP---VNMMPNPPEMNFGLPSLAPLVPPVTVLVP 308
|
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