|
Name |
Accession |
Description |
Interval |
E-value |
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
24-329 |
0e+00 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 561.71 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 24 IDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITT 103
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 104 GSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDA 183
Cdd:TIGR02238 81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 184 VLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVA 263
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEE--PFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVA 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768023179 264 VFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDRLSEREQKASVK 329
Cdd:TIGR02238 239 VFVTNQVQADPGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQ 304
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
2-317 |
0e+00 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 513.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 2 KEDQVVAEepgfqDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLI 81
Cdd:PTZ00035 6 NEQQEEEE-----EEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 82 EPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDT 161
Cdd:PTZ00035 81 PMGFISATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 162 ENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAE 241
Cdd:PTZ00035 161 EGTFRPERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEER--FALLIVDSATALFRVDYSGRGELAE 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 768023179 242 RQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYD 317
Cdd:PTZ00035 239 RQQHLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYD 314
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
101-327 |
2.02e-174 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 484.17 E-value: 2.02e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEA-VFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768023179 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDRLSEREQKAS 327
Cdd:cd19514 160 NVAVFITNQVTADPGAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEAT 226
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
15-327 |
9.77e-159 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 448.84 E-value: 9.77e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 15 DEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEK 94
Cdd:PLN03187 22 DEEEDLFESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQGFITGSDALLK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 95 RKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIA 174
Cdd:PLN03187 102 RKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIA 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 175 DRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQ 254
Cdd:PLN03187 182 ERFGMDADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEP--FRLLIVDSVIALFRVDFTGRGELAERQQKLAQMLSRLT 259
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768023179 255 KISEEYNVAVFVTNQMTADPGAtMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDRLSEREQKAS 327
Cdd:PLN03187 260 KIAEEFNVAVYMTNQVIADPGG-GMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEAEAE 331
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
101-317 |
4.69e-146 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 412.31 E-value: 4.69e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVES--RFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEF 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 768023179 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYD 317
Cdd:cd01123 159 GVAVVVTNQVVAQVDGAMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYD 215
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
1-330 |
3.36e-141 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 404.11 E-value: 3.36e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 1 MKEDQVVAEEPGFQDEEESL-FQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANK 79
Cdd:PLN03186 4 AVAAAAAQAMQEEEEEEAAHgPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 80 LIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFI 159
Cdd:PLN03186 84 LVPLGFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 160 DTENTFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGEL 239
Cdd:PLN03186 164 DTEGTFRPQRLIQIAERFGLNGADVLENVAYARAYNTDHQSELLLEAASMMAETR--FALMIVDSATALYRTEFSGRGEL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 240 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGAtMTFQADPK-KPIGGHILAHASTTRISLRKGRGELRIAKIYDR 318
Cdd:PLN03186 242 SARQMHLGKFLRSLQRLADEFGVAVVITNQVVAQVDG-SAFFAGPQlKPIGGNIMAHASTTRLALRKGRGENRICKVISS 320
|
330
....*....|....
gi 768023179 319 --LSEREQKASVKT 330
Cdd:PLN03186 321 pcLPEAEARFSISS 334
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
24-336 |
1.06e-140 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 401.80 E-value: 1.06e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 24 IDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITT 103
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 104 GSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDA 183
Cdd:TIGR02239 81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 184 VLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVA 263
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVA 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 768023179 264 VFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDR--LSEREQKASVKT--IKDPEE 336
Cdd:TIGR02239 239 VVITNQVVAQVdGAGSMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSpcLPESEAMFAIYEdgIGDPKE 316
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
84-323 |
4.08e-140 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 397.83 E-value: 4.08e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 84 GFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTEN 163
Cdd:pfam08423 2 GFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 164 TFRPDRLRDIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQ 243
Cdd:pfam08423 82 TFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELAERQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 244 QKLAQMLSRLQKISEEYNVAVFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDR--LS 320
Cdd:pfam08423 160 QHLAKFLRTLQRLADEFGVAVVITNQVVAQVdGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSpcLP 239
|
...
gi 768023179 321 ERE 323
Cdd:pfam08423 240 ESE 242
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
101-323 |
6.94e-123 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 353.55 E-value: 6.94e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESR--YALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEF 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768023179 261 NVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDR--LSERE 323
Cdd:cd19513 159 GVAVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSpcLPEAE 223
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
23-334 |
8.67e-113 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 331.07 E-value: 8.67e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 23 DIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIE-PGFLTAFEYSEKRKMVFHI 101
Cdd:PRK04301 5 EKDLEDLPGVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADiGGFETALEVLERRKNVGKI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 102 TTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDH 181
Cdd:PRK04301 85 TTGSKELDELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGLDP 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 182 DAVLDNVLYARAYTSEHQMELLDYvAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 261
Cdd:PRK04301 165 DEVLDNIHVARAYNSDHQMLLAEK-AEELIKEGENIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLYN 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768023179 262 VAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYD--RLSEREQKASVKT--IKDP 334
Cdd:PRK04301 244 AAVVVTNQVMARPDA---FFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDspHLPEGEAVFRITEegIRDA 317
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
31-317 |
3.29e-107 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 316.69 E-value: 3.29e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 31 GINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANKLIEPG-FLTAFEYSEKRKMVFHITTGSQEFD 109
Cdd:TIGR02236 6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 110 KLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVDHDAVLDNVL 189
Cdd:TIGR02236 86 ELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 190 YARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQ 269
Cdd:TIGR02236 166 VARAYNSNHQMLLVEKAEDLIKELNNPVKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQ 245
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 768023179 270 MTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYD 317
Cdd:TIGR02236 246 VMARPDA---FFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVD 290
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
101-323 |
1.56e-97 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 289.26 E-value: 1.56e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 180
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 260
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNNI-KLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLY 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 768023179 261 NVAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYD--RLSERE 323
Cdd:cd19515 160 NIAVLVTNQVMAKPDA---FFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDspHLPEGE 221
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
121-305 |
1.38e-45 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 154.43 E-value: 1.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 121 ITEAFGEFRTGKTQLSHTLCVTAQLPGaggypgGKIIFIDTENTFRPDRLRDIA---DRFNVDHDAVLDNVLYARAYTSE 197
Cdd:cd01393 3 ITEIYGPPGSGKTQLALQLAANALLLG------GGVVWIDTEGAFPPSRLVQILeasPSSELELAEALSRLLYFRPPDTL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 198 HQMELLDYvaakfHEEAGI----FKLLIIDSIMALFRVDF----SGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQ 269
Cdd:cd01393 77 AHLLALDS-----LPESLFpppnTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQ 151
|
170 180 190
....*....|....*....|....*....|....*.
gi 768023179 270 MTADPGAtmTFQADPKKPIGGHILAHASTTRISLRK 305
Cdd:cd01393 152 VTTKIRG--GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
108-305 |
8.44e-42 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 146.28 E-value: 8.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 108 FDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRF-----NVDHD 182
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLpkryhLEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 183 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDF-SGRGELAERQQKLAQMLSRLQKISEEYN 261
Cdd:cd19491 81 NFLDNIFVEHVADLETLEHCLNYQLPALLERGPI-RLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYN 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 768023179 262 VAVFVTNQMTADPGA---------------TMTFQADP----KKPIGGHILAHASTTRISLRK 305
Cdd:cd19491 160 LAVVVVNQVTDRFDSssdasglgvldylsqFSSFSGGVsgnrKVPALGLTWANLVNTRLMLSR 222
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
97-323 |
2.64e-37 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 133.83 E-value: 2.64e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 97 MVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTqlshTLCVTAQLPGAGGypGGKIIFIDTENtFRPDRLRDIADR 176
Cdd:PRK09361 1 MDERLPTGCKMLDELLGGGFERGTITQIYGPPGSGKT----NICLQLAVEAAKN--GKKVIYIDTEG-LSPERFKQIAGE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 177 fnvDHDAVLDNVLYARAYTSEHQ----MELLDYVAAKFheeagifKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSR 252
Cdd:PRK09361 74 ---DFEELLSNIIIFEPSSFEEQseaiRKAEKLAKENV-------GLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTH 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768023179 253 LQKISEEYNVAVFVTNQMTADPGATMTfqadpkKPIGGHILAHASTTRISLRKGRGELRIAKIYDRLSERE 323
Cdd:PRK09361 144 LLKLARKHDLAVVITNQVYSDIDSDGL------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPE 208
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
109-314 |
3.99e-34 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 125.51 E-value: 3.99e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 109 DKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIA-----------DRF 177
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAearfpeafsgfMEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 178 NVDHDAVLDNVLYARAYTSEhqmELLDYVAAKFHE--EAGIfKLLIIDSIMALFRVDFSG-RGELAERQQKLAQMLSRLQ 254
Cdd:cd19493 81 NERAEEMLKRVAVVRVTTLA---QLLERLPNLEEHilSSGV-RLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLK 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 768023179 255 KISEEYNVAVFVTNQMTADPGATMTFQADPKKPIgGHILAHASTTRISLRKGRGELR----IAK 314
Cdd:cd19493 157 RLAEEFRIAVLVTNQATTHFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLQLRrvleIVK 219
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
101-315 |
7.58e-34 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 124.35 E-value: 7.58e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAqlpgagGYPGGKIIFIDTENtFRPDRLRDIA-DRFnv 179
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA------AKQGKKVVYIDTEG-LSPERFQQIAgERF-- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 180 dhDAVLDNVLYARAYTSEHQMELLDYvAAKFhEEAGIFKLLIIDSIMALFRVDfsgRGELAERQQKLAQMLSRLQKISEE 259
Cdd:cd01394 72 --ESIASNIIVFEPYSFDEQGVAIQE-AEKL-LKSDKVDLVVVDSATALYRLE---LGDDSEANRELSRQMSKLLSIARK 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 768023179 260 YNVAVFVTNQMTADpgatmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKI 315
Cdd:cd01394 145 YDIPVVITNQVYSD------IDDDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATL 194
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
71-306 |
2.17e-28 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 113.34 E-value: 2.17e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 71 DKIKEAANKLIEPGFL--TAFEYSEKRKM-VFHITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLSHTLCVTAQLp 146
Cdd:COG0468 11 EKALEAALSQIEKQFGkgSIMRLGDKARQdVEVISTGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 147 gaggyPGGKIIFIDTENTFRPDRlrdiADRFNVDhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIIDSIM 226
Cdd:COG0468 90 -----AGGIAAFIDAEHALDPEY----AKKLGVD----IDNLLVSQPDTGEQALEIAETLV-----RSGAVDLIVVDSVA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 227 ALF-RVDFSGR---GELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGatMTFqADPKKPIGGHILAHASTTRIS 302
Cdd:COG0468 152 ALVpKAEIEGEmgdSHVGLQARLMSQALRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLD 228
|
....
gi 768023179 303 LRKG 306
Cdd:COG0468 229 IRRI 232
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
109-312 |
5.31e-28 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 108.66 E-value: 5.31e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 109 DKLLGGGIESMAITEAFGEFRTGKTqlshTLCVTAQLPGAGGypGGKIIFIDTENtFRPDRLRDIADRfnvDHDAVLDNV 188
Cdd:TIGR02237 2 DELLGGGVERGTITQIYGPPGSGKT----NICMILAVNAARQ--GKKVVYIDTEG-LSPERFKQIAED---RPERALSNF 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 189 LYARAYTSEHQMELLDYvAAKFHEEAGiFKLLIIDSIMALFRVDFSGRGELAERQqkLAQMLSRLQKISEEYNVAVFVTN 268
Cdd:TIGR02237 72 IVFEVFDFDEQGVAIQK-TSKFIDRDS-ASLVVVDSFTALYRLELSDDRISRNRE--LARQLTLLLSLARKKNLAVVITN 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 768023179 269 QMTADPGatmtfqADPKKPIGGHILAHASTTRISLRKGRGELRI 312
Cdd:TIGR02237 148 QVYTDVN------NGTLRPLGGHLLEHWSKVILRLEKFRGRRLA 185
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
121-316 |
6.30e-27 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 104.61 E-value: 6.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 121 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFrpdrlrdiadrfnvdhdavldNVLYARAYTSEHQM 200
Cdd:cd19492 3 ITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVELL 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 201 ELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDFSGrgeLAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTF 280
Cdd:cd19492 62 ALINSLPKFLEDHPKV-KLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISEDGQS 137
|
170 180 190
....*....|....*....|....*....|....*.
gi 768023179 281 QAdpkKPIGGHILAHASTTRISLRKGRGElRIAKIY 316
Cdd:cd19492 138 QL---VPALGESWSHACTTRLFLTWDEKQ-RFAHLY 169
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
113-305 |
1.23e-20 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 88.85 E-value: 1.23e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 113 GGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLpgaggYPGGKIIFIDTENTFRPDRLRDIAD-RFNVDH--DAVLDNVL 189
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAANVAS-----RSGQNVLYIDTKSSFSARRLAQILKsRAQDAEeiDKALQRIR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 190 YARAYTSEHQMELLDYVAAKFHEE----AGIFKLLIIDSIMALFRVDFSGrgelAERQQKLAQM--LSR-LQKISEEYNV 262
Cdd:cd19489 76 VVRVFDPYELLDLLEELRNTLSQQqenlYSRLKLVIIDSLSALISPLLGG----SKHSEGHALLasLARlLKKLAAEYQI 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 768023179 263 AVFVTNQMTADPGatMTFQADPkKPIGGHILAHASTTRISLRK 305
Cdd:cd19489 152 AVLVTNLTVRGGD--GGQQGST-KPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
130-305 |
3.06e-13 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 68.14 E-value: 3.06e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 130 TGKTQLSHTLCVTAQLP-GAGGYP-GGK---IIFIDTENTFRPDRLRDIAD-RFN------------VDHDAV----LDN 187
Cdd:cd19490 12 SGKTELLYHLAARCILPsSWGGVPlGGLeaaVVFIDTDGRFDILRLRSILEaRIRaaiqaanssddeEDVEEIarecLQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 188 VLYARAYTSEH---QMELLDYVAAK--FHEEAGifkLLIIDSIMALFRVDFSGRGELAERQQK----LAQMLSRLQKISE 258
Cdd:cd19490 92 LHIFRCHSSLQllaTLLSLENYLLSlsANPELG---LLLIDSISAFYWQDRFSAELARAAPLLqeaaLRAILRELRRLRR 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 768023179 259 EYNVAVFVTNQM-----------TADPGATMTFQADPKKPIGGHILAHASTTRISLRK 305
Cdd:cd19490 169 RFQLVVIATKQAlfpgksastdnPAANNAVSKASAPSHREYLPRPWQRLVTHRLVLSR 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
101-323 |
1.14e-10 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 60.70 E-value: 1.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIE---SMAITeafGEFRTGKTQLSHTLCVtaqlpgAGGYPGGKIIFIDTENtfRPDRLRDIADRF 177
Cdd:COG0467 2 VPTGIPGLDELLGGGLPrgsSTLLS---GPPGTGKTTLALQFLA------EGLRRGEKGLYVSFEE--SPEQLLRRAESL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 178 NVDHDAVLDN--VLYARAYTSEHQM---ELLDYVAAKFHEEAGifKLLIIDSIMALFRvdfsgrgeLAERQQKLAQMLSR 252
Cdd:COG0467 71 GLDLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGA--KRVVIDSLSGLLL--------ALPDPERLREFLHR 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 768023179 253 LQKISEEYNVAVFVTNQMTADPGatmtfqadpkkPIGGHILAHASTTRISLRK--GRGE----LRIAKIYDRLSERE 323
Cdd:COG0467 141 LLRYLKKRGVTTLLTSETGGLED-----------EATEGGLSYLADGVILLRYveLGGElrraLSVLKMRGSAHDRT 206
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
72-333 |
1.12e-09 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 58.56 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 72 KIKEAANKLIEPGF-------LTafeySEKRKMVFHITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLshTLCVTA 143
Cdd:pfam00154 1 KALEAALKQIEKQFgkgsimkLG----DEKKLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL--ALHAIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 144 QLPGAGGYpggkIIFIDTENTFRPdrlrDIADRFNVDhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIID 223
Cdd:pfam00154 75 EAQKAGGT----AAFIDAEHALDP----VYAKKLGVD----IDNLLVSQPDTGEQALEIADMLV-----RSGAIDLIVVD 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 224 SIMALF-RVDFSgrGELAERQQKL-AQMLSR-LQKIS---EEYNVAVFVTNQMTADPGatMTFqADPKKPIGGHILAHAS 297
Cdd:pfam00154 138 SVAALVpKAEIE--GEMGDSHVGLqARLMSQaLRKLTgsiSKSNTTVIFINQIREKIG--VMF-GNPETTTGGRALKFYA 212
|
250 260 270
....*....|....*....|....*....|....*.
gi 768023179 298 TTRISLRkgrgelRIAKIYDRLSEREQKASVKTIKD 333
Cdd:pfam00154 213 SVRLDIR------RIGQIKQGEEVIGNKTKVKVVKN 242
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
101-306 |
3.63e-09 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 56.41 E-value: 3.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLG-GGIESMAITEAFGEFRTGKTQLshTLCVTAQLPGAGGYpggkIIFIDTENTFRPdrlrDIADRFNV 179
Cdd:cd00983 5 IPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTL--ALHAIAEAQKLGGT----AAFIDAEHALDP----EYAKKLGV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 180 DhdavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIIDSIMALF-RVDFSgrGELAERQQKL-AQMLSR-LQKI 256
Cdd:cd00983 75 D----IDNLLVSQPDTGEQALEIADTLI-----RSGAVDLIVVDSVAALVpKAEIE--GEMGDSHVGLqARLMSQaLRKL 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 768023179 257 S---EEYNVAVFVTNQMTADPGatmTFQADPKKPIGGHILAHASTTRISLRKG 306
Cdd:cd00983 144 TgslSKSKTTVIFINQLREKIG---VMFGNPETTTGGNALKFYASVRLDIRRI 193
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
101-311 |
7.22e-08 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 52.65 E-value: 7.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTqlshTLCvtAQLPGAGGYPGGKIIFIDTENTfrPDRLRDIADRFNVD 180
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKT----LFG--LQFLYAGAKNGEPGLFFTFEES--PERLLRNAKSFGWD 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDA--VLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKL--LIIDSIMALFRvdfsgrgeLAERQQKLAQMLSRLQKI 256
Cdd:cd01124 73 FDEmeDEGKLIIVDAPPTEAGRFSLDELLSRILSIIKSFKAkrVVIDSLSGLRR--------AKEDQMRARRIVIALLNE 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 768023179 257 SEEYNVAVFVTNQMTADPGATMTfqadpkkpiGGHILAHASTTRISLRK--GRGELR 311
Cdd:cd01124 145 LRAAGVTTIFTSEMRSFLSSESA---------GGGDVSFIVDGVILLRYveIEGELR 192
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
25-79 |
4.81e-05 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 40.55 E-value: 4.81e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 768023179 25 DLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVDKIKEAANK 79
Cdd:pfam14520 3 ELLSISGIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
101-273 |
4.42e-04 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 41.36 E-value: 4.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLShtLCVTAQLPGAggypGGKIIFIDTENTFRPDRLRdiADRFNVD 180
Cdd:cd01121 64 ISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKSTLL--LQVAARLAQR----GGKVLYVSGEESLSQIKLR--AERLGLG 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 181 HDAvldnvLYARAYTSehqmelLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGR-GELAE-RQqkLAQMLSRLQKise 258
Cdd:cd01121 136 SDN-----LYLLAETN------LEAILAEIEELK--PSLVVIDSIQTVYSPELTSSpGSVSQvRE--CAAELLRLAK--- 197
|
170
....*....|....*
gi 768023179 259 EYNVAVFVTNQMTAD 273
Cdd:cd01121 198 ETGIPVFLVGHVTKD 212
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
109-267 |
8.53e-04 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 40.06 E-value: 8.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 109 DKLLGGGIESMAITEAFGEFRTGKT----QLShtLCVTAQLPGAGGYP---GGKIIFIDTENTFR--PDRLRDIADRFNV 179
Cdd:pfam13481 23 RWLIKGLLPAGGLGLLAGAPGTGKTtlalDLA--AAVATGKPWLGGPRvpeQGKVLYVSAEGPADelRRRLRAAGADLDL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 180 D-----HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDFSGRGElaerqqkLAQMLSRLQ 254
Cdd:pfam13481 101 ParllfLSLVESLPLFFLDRGGPLLDADVDALEAALEEVEDP-DLVVIDPLARALGGDENSNSD-------VGRLVKALD 172
|
170
....*....|...
gi 768023179 255 KISEEYNVAVFVT 267
Cdd:pfam13481 173 RLARRTGATVLLV 185
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
101-276 |
5.36e-03 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 37.89 E-value: 5.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 101 ITTGSQEFDKLLGGGI--ESMAITEafGEFRTGKTQLSHTLCVTAQLPGAggypggKIIFIDTENTFRpDRLR------- 171
Cdd:COG2874 3 ISTGNDELDKRLGGGIplGSLVLIE--GENGTGKSVLSQQFAYGALENGL------SVTYISTELTTK-EFIKqmkslsy 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768023179 172 DIADRFnvdhdavLDNVL-------YARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDfsgrgelaeRQQ 244
Cdd:COG2874 74 DISDYL-------LRGRLlflpvhpLGFEWNSKQRKDLLKRLMKYIASNLWEADVIIIDSLSALLRNA---------EES 137
|
170 180 190
....*....|....*....|....*....|..
gi 768023179 245 KLAQMLSRLQKISEEYNVAVfvtnqMTADPGA 276
Cdd:COG2874 138 AILDFITFFKNLVDLGKTII-----LTVHPSA 164
|
|
| |
