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Conserved domains on  [gi|768024832|ref|XP_011528480|]
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SRR1-like protein isoform X1 [Homo sapiens]

Protein Classification

SRR1 family protein( domain architecture ID 10546804)

SRR1 family protein similar to Saccharomyces cerevisiae SRR1-like protein BER1 that is involved in microtubule stability and kinetochore function

Gene Ontology:  GO:0007017

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SRR1 pfam07985
SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock ...
69-226 1.03e-49

SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock in Arabidopsis. This presumed domain has a Rossmann-like fold and structural models suggest it may have a methyltransferase function.


:

Pssm-ID: 462330  Cd Length: 170  Bit Score: 161.36  E-value: 1.03e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832   69 KCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRS-HCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIrGEPTIFYM 147
Cdd:pfam07985  17 KIVCLGLGSFEESRRARYQLALLLELVELLKIPGSiNVYAYDPVFTELDKEFLESLGIEVLSENPEGFREV-DEPTLFYM 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832  148 LHCGTALYNNLLWSNWsvdalsKMVIIGNSFKGLEERLLARILQKNYPYIAKILKGLEELEFPQT--SQYMDIFNDTSVH 225
Cdd:pfam07985  96 PHCPLELYENLLAANS------PAVLLGNSLEAYTDRLTKRELKEKYPYISLVHLLEETENNFELlaIPWENAFNDLSLH 169

                  .
gi 768024832  226 W 226
Cdd:pfam07985 170 W 170
 
Name Accession Description Interval E-value
SRR1 pfam07985
SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock ...
69-226 1.03e-49

SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock in Arabidopsis. This presumed domain has a Rossmann-like fold and structural models suggest it may have a methyltransferase function.


Pssm-ID: 462330  Cd Length: 170  Bit Score: 161.36  E-value: 1.03e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832   69 KCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRS-HCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIrGEPTIFYM 147
Cdd:pfam07985  17 KIVCLGLGSFEESRRARYQLALLLELVELLKIPGSiNVYAYDPVFTELDKEFLESLGIEVLSENPEGFREV-DEPTLFYM 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832  148 LHCGTALYNNLLWSNWsvdalsKMVIIGNSFKGLEERLLARILQKNYPYIAKILKGLEELEFPQT--SQYMDIFNDTSVH 225
Cdd:pfam07985  96 PHCPLELYENLLAANS------PAVLLGNSLEAYTDRLTKRELKEKYPYISLVHLLEETENNFELlaIPWENAFNDLSLH 169

                  .
gi 768024832  226 W 226
Cdd:pfam07985 170 W 170
PLN03093 PLN03093
Protein SENSITIVITY TO RED LIGHT REDUCED 1; Provisional
68-227 5.29e-23

Protein SENSITIVITY TO RED LIGHT REDUCED 1; Provisional


Pssm-ID: 178641  Cd Length: 273  Bit Score: 94.92  E-value: 5.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832  68 LKCVCYGIGNFATCIVARNQLTFLLLllekcqIPRSHCW-----VYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIRgEP 142
Cdd:PLN03093  99 MQMVIYGIGSIESYETPRFQLSLAIL------MKREFDWigdieVFDPVLSATESRVLESLGCSVLSVNEQGRREAT-KP 171
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832 143 TIFYMLHCGTALYNNLLWSNWSVDALSKMVIIGNSFKGLEERL---LARILQKNYPYIAKILKGLEELEFPQTSQ-YMDI 218
Cdd:PLN03093 172 TLFFMPHCEAELYNNLLQANWRMERLNHIALFGNSFEMYEEQVsefFNSEVVDSTKHILAARKFTSEFAIKTVSDdYFAA 251

                 ....*....
gi 768024832 219 FNDTSVHWF 227
Cdd:PLN03093 252 FHDSSWHFF 260
 
Name Accession Description Interval E-value
SRR1 pfam07985
SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock ...
69-226 1.03e-49

SRR1 domain; SRR1 proteins are signalling proteins involved in regulating the circadian clock in Arabidopsis. This presumed domain has a Rossmann-like fold and structural models suggest it may have a methyltransferase function.


Pssm-ID: 462330  Cd Length: 170  Bit Score: 161.36  E-value: 1.03e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832   69 KCVCYGIGNFATCIVARNQLTFLLLLLEKCQIPRS-HCWVYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIrGEPTIFYM 147
Cdd:pfam07985  17 KIVCLGLGSFEESRRARYQLALLLELVELLKIPGSiNVYAYDPVFTELDKEFLESLGIEVLSENPEGFREV-DEPTLFYM 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832  148 LHCGTALYNNLLWSNWsvdalsKMVIIGNSFKGLEERLLARILQKNYPYIAKILKGLEELEFPQT--SQYMDIFNDTSVH 225
Cdd:pfam07985  96 PHCPLELYENLLAANS------PAVLLGNSLEAYTDRLTKRELKEKYPYISLVHLLEETENNFELlaIPWENAFNDLSLH 169

                  .
gi 768024832  226 W 226
Cdd:pfam07985 170 W 170
PLN03093 PLN03093
Protein SENSITIVITY TO RED LIGHT REDUCED 1; Provisional
68-227 5.29e-23

Protein SENSITIVITY TO RED LIGHT REDUCED 1; Provisional


Pssm-ID: 178641  Cd Length: 273  Bit Score: 94.92  E-value: 5.29e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832  68 LKCVCYGIGNFATCIVARNQLTFLLLllekcqIPRSHCW-----VYDPLFSQLEIEVLNTLGVTVLSENEEGKRSIRgEP 142
Cdd:PLN03093  99 MQMVIYGIGSIESYETPRFQLSLAIL------MKREFDWigdieVFDPVLSATESRVLESLGCSVLSVNEQGRREAT-KP 171
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768024832 143 TIFYMLHCGTALYNNLLWSNWSVDALSKMVIIGNSFKGLEERL---LARILQKNYPYIAKILKGLEELEFPQTSQ-YMDI 218
Cdd:PLN03093 172 TLFFMPHCEAELYNNLLQANWRMERLNHIALFGNSFEMYEEQVsefFNSEVVDSTKHILAARKFTSEFAIKTVSDdYFAA 251

                 ....*....
gi 768024832 219 FNDTSVHWF 227
Cdd:PLN03093 252 FHDSSWHFF 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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