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Conserved domains on  [gi|767980331|ref|XP_011534969|]
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centrosomal protein of 170 kDa protein B isoform X4 [Homo sapiens]

Protein Classification

centrosomal protein of 170 kDa( domain architecture ID 12173055)

centrosomal protein of 170 kDa plays a role in microtubule organization and is required for centriole subdistal appendage assembly

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CEP170_C pfam15308
CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa ...
263-946 0e+00

CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa (CEP170).


:

Pssm-ID: 464633  Cd Length: 682  Bit Score: 974.20  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   263 GRMVIQL-RPGRSPEPDGPAPA--FLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDfHSQDTHLILKETE 339
Cdd:pfam15308    1 GRSAIQLqTQDKSPEPDKEASSksFVRQESFTKEKPSGNVPIEKLPHISSHPLLRDLERSRSARMD-HSQDTHLILKETE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   340 TALAALEARLLSNSVDAECEGgSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQP--LRAQKEMSPSPPAAQDPG 417
Cdd:pfam15308   80 TALAALEAKLLSESKGDEGEG-SPSGQPEDSLSGESDVDTASTVSLVSGKNEPSSTQKRKsiSSLQKEKSSSSPSAQDKG 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   418 GTAlvSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEatgagRL 497
Cdd:pfam15308  159 SQP--SARERLSEKRRKSRTPDDGGRAEAARRFQSRRSRGPRGSLDLTDDEQTSSLPHLPISDIVSSDHETYS-----RP 231
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   498 GSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRP 577
Cdd:pfam15308  232 SSRRKPFTSPDLLAQKEEQSKSSKSSQKVQQVLTRSNSLSTPRPTRASLLRRARLGDASDNELADTDRASVASEVSATSK 311
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   578 AAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSR 657
Cdd:pfam15308  312 PPTEAKKLSRLDILAMPRKRAGSFTAPSDSEATTSRSGFSGRSVELYCSSRKGTVSEARAAARKTARTRANSISKQPFSR 391
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   658 ARSGSARY--TSNTRRRQQGSDYTSTSEEEYGSRHGSPKHTRSHTSTATQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 735
Cdd:pfam15308  392 TRSSSAKYssSSNSRRRQQGSDYTSTSEEEYGSNHNSPKHKRSHTSTATQTPRAQGTGTARQKPPGHRETEEEEYQPDPY 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   736 GFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQ 815
Cdd:pfam15308  472 PFQDWTAHSAEIARLSQDLAKDLAILAREIHDVAGDGDSQSSSGTAPSTSLSSVPNTPASTISAREELVQHIPEASLNFQ 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   816 KVPPGSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEA 895
Cdd:pfam15308  552 KVPPGSNGRKDLDQNMNDSREDQLAKKRRPWNREEVILDNLMLNPVSQLSQAIRENTEQLAEKMKILFQNKDRNWEEIEA 631
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767980331   896 RINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGN 946
Cdd:pfam15308  632 KINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPDGTLDALTSN 682
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
64-303 6.27e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 6.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   64 PQAEHQGLPVPGSPGGQKW-VSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERA-----DSPAGPE 137
Cdd:PHA03307  212 PISASASSPAPAPGRSAADdAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSsrpgpASSSSSP 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  138 SSRRSGPGPP-ELDSEQPSRLFGQEELDPDSLSD----ASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGE 212
Cdd:PHA03307  292 RERSPSPSPSsPGSGPAPSSPRASSSSSSSRESSssstSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRP 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  213 PTPASFfigdqngdavlsrkPLAAPGDGEGLGQTAQPSPPARDGvyvSANGRMVIQLRPGRSPEPDGPAPAFLRQE---- 288
Cdd:PHA03307  372 SRAPSS--------------PAASAGRPTRRRARAAVAGRARRR---DATGRFPAGRPRPSPLDAGAASGAFYARYpllt 434
                         250
                  ....*....|....*.
gi 767980331  289 -SFTKEPASGPPAPGK 303
Cdd:PHA03307  435 pSGEPWPGSPPPPPGR 450
 
Name Accession Description Interval E-value
CEP170_C pfam15308
CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa ...
263-946 0e+00

CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa (CEP170).


Pssm-ID: 464633  Cd Length: 682  Bit Score: 974.20  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   263 GRMVIQL-RPGRSPEPDGPAPA--FLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDfHSQDTHLILKETE 339
Cdd:pfam15308    1 GRSAIQLqTQDKSPEPDKEASSksFVRQESFTKEKPSGNVPIEKLPHISSHPLLRDLERSRSARMD-HSQDTHLILKETE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   340 TALAALEARLLSNSVDAECEGgSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQP--LRAQKEMSPSPPAAQDPG 417
Cdd:pfam15308   80 TALAALEAKLLSESKGDEGEG-SPSGQPEDSLSGESDVDTASTVSLVSGKNEPSSTQKRKsiSSLQKEKSSSSPSAQDKG 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   418 GTAlvSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEatgagRL 497
Cdd:pfam15308  159 SQP--SARERLSEKRRKSRTPDDGGRAEAARRFQSRRSRGPRGSLDLTDDEQTSSLPHLPISDIVSSDHETYS-----RP 231
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   498 GSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRP 577
Cdd:pfam15308  232 SSRRKPFTSPDLLAQKEEQSKSSKSSQKVQQVLTRSNSLSTPRPTRASLLRRARLGDASDNELADTDRASVASEVSATSK 311
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   578 AAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSR 657
Cdd:pfam15308  312 PPTEAKKLSRLDILAMPRKRAGSFTAPSDSEATTSRSGFSGRSVELYCSSRKGTVSEARAAARKTARTRANSISKQPFSR 391
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   658 ARSGSARY--TSNTRRRQQGSDYTSTSEEEYGSRHGSPKHTRSHTSTATQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 735
Cdd:pfam15308  392 TRSSSAKYssSSNSRRRQQGSDYTSTSEEEYGSNHNSPKHKRSHTSTATQTPRAQGTGTARQKPPGHRETEEEEYQPDPY 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   736 GFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQ 815
Cdd:pfam15308  472 PFQDWTAHSAEIARLSQDLAKDLAILAREIHDVAGDGDSQSSSGTAPSTSLSSVPNTPASTISAREELVQHIPEASLNFQ 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   816 KVPPGSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEA 895
Cdd:pfam15308  552 KVPPGSNGRKDLDQNMNDSREDQLAKKRRPWNREEVILDNLMLNPVSQLSQAIRENTEQLAEKMKILFQNKDRNWEEIEA 631
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767980331   896 RINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGN 946
Cdd:pfam15308  632 KINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPDGTLDALTSN 682
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
47-478 1.53e-06

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 52.38  E-value: 1.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   47 QRMALLQEFASRPLGAAPQA-EHQGLPvPGSPG------GQKWVSRWASLADSYSDPGLTEDG-LGRRGGEPE----GSL 114
Cdd:PTZ00449  494 KKLAPIEEEDSDKHDEPPEGpEASGLP-PKAPGdkegeeGEHEDSKESDEPKEGGKPGETKEGeVGKKPGPAKehkpSKI 572
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  115 PVRMRRrlPQLPsERADSPAGPESSRRS-GPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRS 193
Cdd:PTZ00449  573 PTLSKK--PEFP-KDPKHPKDPEEPKKPkRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPE 649
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  194 PQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANgRMVIQLRPgR 273
Cdd:PTZ00449  650 GPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTP-RPLPPKLP-R 727
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  274 SP--------EPDGPAPA----FLRQES---FTKEPASGPPAPG------KPPHISSHPLLQDLAATRAARMDFHSqDTH 332
Cdd:PTZ00449  728 DEefpfepigDPDAEQPDdiefFTPPEEertFFHETPADTPLPDilaeefKEEDIHAETGEPDEAMKRPDSPSEHE-DKP 806
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  333 LILKETETALAALEARLLSNSVDAECEGGSTPRPPedalsgdsdvdTASTVSLRSGKSGPSPTTpqpLRAQKEMSPSPPA 412
Cdd:PTZ00449  807 PGDHPSLPKKRHRLDGLALSTTDLESDAGRIAKDA-----------SGKIVKLKRSKSFDDLTT---VEEAEEMGAEARK 872
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767980331  413 -AQDPGGTalvsareQSSERQHHPlgPTDMGRGEPVRRSAIRRGHRPRGSLDwPSEERGPVLAHLPS 478
Cdd:PTZ00449  873 iVVDDDGT-------EADDEDTHP--PEEKHKSEVRRRRPPKKPSKPKKPSK-PKKPKKPDSAFIPS 929
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
64-303 6.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 6.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   64 PQAEHQGLPVPGSPGGQKW-VSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERA-----DSPAGPE 137
Cdd:PHA03307  212 PISASASSPAPAPGRSAADdAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSsrpgpASSSSSP 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  138 SSRRSGPGPP-ELDSEQPSRLFGQEELDPDSLSD----ASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGE 212
Cdd:PHA03307  292 RERSPSPSPSsPGSGPAPSSPRASSSSSSSRESSssstSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRP 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  213 PTPASFfigdqngdavlsrkPLAAPGDGEGLGQTAQPSPPARDGvyvSANGRMVIQLRPGRSPEPDGPAPAFLRQE---- 288
Cdd:PHA03307  372 SRAPSS--------------PAASAGRPTRRRARAAVAGRARRR---DATGRFPAGRPRPSPLDAGAASGAFYARYpllt 434
                         250
                  ....*....|....*.
gi 767980331  289 -SFTKEPASGPPAPGK 303
Cdd:PHA03307  435 pSGEPWPGSPPPPPGR 450
 
Name Accession Description Interval E-value
CEP170_C pfam15308
CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa ...
263-946 0e+00

CEP170 C-terminus; This family includes the C-terminus of centrosomal protein of 170 kDa (CEP170).


Pssm-ID: 464633  Cd Length: 682  Bit Score: 974.20  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   263 GRMVIQL-RPGRSPEPDGPAPA--FLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDfHSQDTHLILKETE 339
Cdd:pfam15308    1 GRSAIQLqTQDKSPEPDKEASSksFVRQESFTKEKPSGNVPIEKLPHISSHPLLRDLERSRSARMD-HSQDTHLILKETE 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   340 TALAALEARLLSNSVDAECEGgSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQP--LRAQKEMSPSPPAAQDPG 417
Cdd:pfam15308   80 TALAALEAKLLSESKGDEGEG-SPSGQPEDSLSGESDVDTASTVSLVSGKNEPSSTQKRKsiSSLQKEKSSSSPSAQDKG 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   418 GTAlvSAREQSSERQHHPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASNHETPEatgagRL 497
Cdd:pfam15308  159 SQP--SARERLSEKRRKSRTPDDGGRAEAARRFQSRRSRGPRGSLDLTDDEQTSSLPHLPISDIVSSDHETYS-----RP 231
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   498 GSRRKPAAPPPSPAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRP 577
Cdd:pfam15308  232 SSRRKPFTSPDLLAQKEEQSKSSKSSQKVQQVLTRSNSLSTPRPTRASLLRRARLGDASDNELADTDRASVASEVSATSK 311
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   578 AAEQAKKLSRLDILAMPRKRAGSFTGTSDPEAAPARTSFSGRSVELCCASRKPTMAEARAVSRKAANTATTTGPRQPFSR 657
Cdd:pfam15308  312 PPTEAKKLSRLDILAMPRKRAGSFTAPSDSEATTSRSGFSGRSVELYCSSRKGTVSEARAAARKTARTRANSISKQPFSR 391
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   658 ARSGSARY--TSNTRRRQQGSDYTSTSEEEYGSRHGSPKHTRSHTSTATQTPRAGSSSRARSRAPGPRDTDDDEEEPDPY 735
Cdd:pfam15308  392 TRSSSAKYssSSNSRRRQQGSDYTSTSEEEYGSNHNSPKHKRSHTSTATQTPRAQGTGTARQKPPGHRETEEEEYQPDPY 471
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   736 GFIVQTAEIAEIARLSQTLVKDVAILAQEIHDVAGDGDTLGSSEPAHSASLSNMPSTPASTISAREELVQRIPEASLNFQ 815
Cdd:pfam15308  472 PFQDWTAHSAEIARLSQDLAKDLAILAREIHDVAGDGDSQSSSGTAPSTSLSSVPNTPASTISAREELVQHIPEASLNFQ 551
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   816 KVPPGSLNSRDFDQNMNDSCEDALANKTRPRNREEVIFDNLMLNPVSQLSQAIRENTEHLAEKMKILFQNTGRAWEDLEA 895
Cdd:pfam15308  552 KVPPGSNGRKDLDQNMNDSREDQLAKKRRPWNREEVILDNLMLNPVSQLSQAIRENTEQLAEKMKILFQNKDRNWEEIEA 631
                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 767980331   896 RINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPSGSLDLLTGN 946
Cdd:pfam15308  632 KINAENEVPILKTSNKEISSILKELRRVQKQLEVINAIVDPDGTLDALTSN 682
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
47-478 1.53e-06

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 52.38  E-value: 1.53e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   47 QRMALLQEFASRPLGAAPQA-EHQGLPvPGSPG------GQKWVSRWASLADSYSDPGLTEDG-LGRRGGEPE----GSL 114
Cdd:PTZ00449  494 KKLAPIEEEDSDKHDEPPEGpEASGLP-PKAPGdkegeeGEHEDSKESDEPKEGGKPGETKEGeVGKKPGPAKehkpSKI 572
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  115 PVRMRRrlPQLPsERADSPAGPESSRRS-GPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRS 193
Cdd:PTZ00449  573 PTLSKK--PEFP-KDPKHPKDPEEPKKPkRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPE 649
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  194 PQEGPTWSRGRRSPRAPGEPTPASFFIGDQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANgRMVIQLRPgR 273
Cdd:PTZ00449  650 GPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTP-RPLPPKLP-R 727
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  274 SP--------EPDGPAPA----FLRQES---FTKEPASGPPAPG------KPPHISSHPLLQDLAATRAARMDFHSqDTH 332
Cdd:PTZ00449  728 DEefpfepigDPDAEQPDdiefFTPPEEertFFHETPADTPLPDilaeefKEEDIHAETGEPDEAMKRPDSPSEHE-DKP 806
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  333 LILKETETALAALEARLLSNSVDAECEGGSTPRPPedalsgdsdvdTASTVSLRSGKSGPSPTTpqpLRAQKEMSPSPPA 412
Cdd:PTZ00449  807 PGDHPSLPKKRHRLDGLALSTTDLESDAGRIAKDA-----------SGKIVKLKRSKSFDDLTT---VEEAEEMGAEARK 872
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767980331  413 -AQDPGGTalvsareQSSERQHHPlgPTDMGRGEPVRRSAIRRGHRPRGSLDwPSEERGPVLAHLPS 478
Cdd:PTZ00449  873 iVVDDDGT-------EADDEDTHP--PEEKHKSEVRRRRPPKKPSKPKKPSK-PKKPKKPDSAFIPS 929
PHA03247 PHA03247
large tegument protein UL36; Provisional
120-582 2.00e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 45.70  E-value: 2.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  120 RRLPQLPSERADSPAGPEssrrsgpgPPELDSEQPSRLFGQEELDPDSLSDASGSdggRGPEPGVEPQDSRRRSPQEgpt 199
Cdd:PHA03247 2538 RGLEELASDDAGDPPPPL--------PPAAPPAAPDRSVPPPRPAPRPSEPAVTS---RARRPDAPPQSARPRAPVD--- 2603
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  200 wsrGRRSPRAPGEPTPASffigdQNGDAVLSRKPLAAPGDGEGLGQTAQPSPPARDGVYVSANGRMVIQLR-------PG 272
Cdd:PHA03247 2604 ---DRGDPRGPAPPSPLP-----PDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRarrlgraAQ 2675
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  273 RSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAarmdfhsqdthlilketetalaalearllsn 352
Cdd:PHA03247 2676 ASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG------------------------------- 2724
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  353 svdAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTP-QPLRAQKEMSPSPPAAQDPGGTALVSAREQSSEr 431
Cdd:PHA03247 2725 ---PAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPpAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS- 2800
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  432 qhhPLGPTDMGRGEPVRRSAIRRGHRPRGSLDWPSEERgPVLAHLPSSDVmasnhETPEATGAGRL--GSRRKPAAPPPS 509
Cdd:PHA03247 2801 ---PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ-PTAPPPPPGPP-----PPSLPLGGSVApgGDVRRRPPSRSP 2871
                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767980331  510 PAAREEQSRSSASSQKGPQALTRSNSLSTPRPTRASRLRRARLGDASDTEAADGERGSLGNPEPVGRPAAEQA 582
Cdd:PHA03247 2872 AAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944
PHA03247 PHA03247
large tegument protein UL36; Provisional
116-541 4.86e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.54  E-value: 4.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  116 VRMRRRLPQLPSERAdSPAGPESSRRSGPGPPELDSEQPSrlfgQEELDPDSLSDASGSDGGRGPEPGVEPQDSRRRSPQ 195
Cdd:PHA03247 2582 VTSRARRPDAPPQSA-RPRAPVDDRGDPRGPAPPSPLPPD----THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP 2656
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  196 EGPTWSRGRRSpRAPGEPTPASffigdqngdAVLSR-KPLAAPGDGEGLGQTAQPSPPARDgvyvsangrmviqlrPGRS 274
Cdd:PHA03247 2657 APGRVSRPRRA-RRLGRAAQAS---------SPPQRpRRRAARPTVGSLTSLADPPPPPPT---------------PEPA 2711
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  275 PEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMDFHSQDTHLILKETETALAALEARLLSNSV 354
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASL 2791
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  355 DAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPPAAQDPGGTAlvsareqsserqhh 434
Cdd:PHA03247 2792 SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA-------------- 2857
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  435 PLGPtdmgrgepvrrsaIRRGHRPRGSLDWPSEERGPVLAHLPSSDVMASnhetPEATGAGRLGSRRKPAAPPPSPAARE 514
Cdd:PHA03247 2858 PGGD-------------VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRS----TESFALPPDQPERPPQPQAPPPPQPQ 2920
                         410       420
                  ....*....|....*....|....*..
gi 767980331  515 EQSRSSASSQKGPQALTRSNSLSTPRP 541
Cdd:PHA03247 2921 PQPPPPPQPQPPPPPPPRPQPPLAPTT 2947
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
92-442 2.98e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   92 SYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDA 171
Cdd:PHA03307  105 SPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETAR 184
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  172 SGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPAsffigDQNGDAVLSRKPLAAPGDGEGlGQTAQPSP 251
Cdd:PHA03307  185 APSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAA-----DDAGASSSDSSSSESSGCGWG-PENECPLP 258
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  252 PARDGVYVSANGRMVIQLRPGRSPEPDGPAPAFLRqesftKEPASGPPAPGKPPHISSHPLLQDLAATRAArmdfhsqdt 331
Cdd:PHA03307  259 RPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRE-----RSPSPSPSSPGSGPAPSSPRASSSSSSSRES--------- 324
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  332 hlilketetalaaleARLLSNSVDAECEGGSTPRPPEDALSGDSDVDTASTVSLRSGKSGPSPTTPQPLRAQKEMSPSPP 411
Cdd:PHA03307  325 ---------------SSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRR 389
                         330       340       350
                  ....*....|....*....|....*....|.
gi 767980331  412 AAQDPGGTALVSAREQSSERQHHPLGPTDMG 442
Cdd:PHA03307  390 ARAAVAGRARRRDATGRFPAGRPRPSPLDAG 420
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
64-303 6.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.54  E-value: 6.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331   64 PQAEHQGLPVPGSPGGQKW-VSRWASLADSYSDPGLTEDGLGRRGGEPEGSLPVRMRRRLPQLPSERA-----DSPAGPE 137
Cdd:PHA03307  212 PISASASSPAPAPGRSAADdAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSsrpgpASSSSSP 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  138 SSRRSGPGPP-ELDSEQPSRLFGQEELDPDSLSD----ASGSDGGRGPEPGVEPQDSRRRSPQEGPTWSRGRRSPRAPGE 212
Cdd:PHA03307  292 RERSPSPSPSsPGSGPAPSSPRASSSSSSSRESSssstSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRP 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  213 PTPASFfigdqngdavlsrkPLAAPGDGEGLGQTAQPSPPARDGvyvSANGRMVIQLRPGRSPEPDGPAPAFLRQE---- 288
Cdd:PHA03307  372 SRAPSS--------------PAASAGRPTRRRARAAVAGRARRR---DATGRFPAGRPRPSPLDAGAASGAFYARYpllt 434
                         250
                  ....*....|....*.
gi 767980331  289 -SFTKEPASGPPAPGK 303
Cdd:PHA03307  435 pSGEPWPGSPPPPPGR 450
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
104-325 8.25e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 8.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  104 GRRGGEPEGSLPVRMRRRLPQLPSERADSPAGPESSRRSGPGPPELDSEQPSRLFGQEELDPDSLSDASGSDGGRGPEPG 183
Cdd:PRK07764  590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767980331  184 VEPQDSRRRSPQEGPTWSRGRRSPRAPGEPTPASffigdqngdavlsrKPLAAPGDGEGLGQTAQPSPPARDGVYVSANG 263
Cdd:PRK07764  670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP--------------APAATPPAGQADDPAAQPPQAAQGASAPSPAA 735
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767980331  264 RMVIQLRPGRSPEPDGPAPAFLRQESFTKEPASGPPAPGKPPHISSHPLLQDLAATRAARMD 325
Cdd:PRK07764  736 DDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDED 797
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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