|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
126-421 |
3.05e-126 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 366.52 E-value: 3.05e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 126 TLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTS 205
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 206 LYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGEaLSPVSLLADpSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKK 285
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGG-EKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 286 KGCEQVLWLYGPDHELTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 365
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 927141679 366 LehgrvrEVFGSGTACQVCPVHRILYQGKFlhiPTMENGPELILRFYNELKMIQYG 421
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
78-431 |
6.66e-122 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 358.31 E-value: 6.66e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 78 EMTREPHKKPDPSEcLLFGKTFTDHMLMVEWNMEKgWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLF 157
Cdd:PRK13357 8 NPTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 158 RPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSA-GTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPV 236
Cdd:PRK13357 86 RPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 237 GAYFPGEAlSPVSLLADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIF-VFwt 314
Cdd:PRK13357 166 GAYFKGGV-KPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 315 hEDGaleLVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRALEHGRVREVFGSGTACQVCPVHRILYQGK 394
Cdd:PRK13357 243 -KDG---TVTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDK 317
|
330 340 350
....*....|....*....|....*....|....*....
gi 927141679 395 FLHIPTMENGPeLILRFYNELKMIQYGTKA--HEWMLQV 431
Cdd:PRK13357 318 EFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
114-431 |
1.46e-93 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 284.34 E-value: 1.46e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 114 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEV 193
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 194 DRDWVPDS-AGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGN 272
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKG-GLAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 273 YGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFvFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGeFR 351
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFF-FITG-DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 352 VTERKMTMNEFLRALEHGrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpELILRFYNELKMIQYGTKA--HEWML 429
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 927141679 430 QV 431
Cdd:TIGR01123 312 EV 313
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
114-424 |
5.11e-65 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 210.05 E-value: 5.11e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 114 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVE 192
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 193 VDRDwvpdsagTSLYVRPVLIGNEPSLGVGSPTH-ALLYVILCPVGAYFPGEALSPVSLLADPsFIRAWVGGVGDCKiGG 271
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEYePTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 272 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGe 349
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL---DTDgyVAEGSGSNVFIV---KDG--VLVTPPLSGGILPGITRDSVIELARELG- 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 927141679 350 FRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRIlyQGKflHIPTMENGPeLILRFYNELKMIQYGTKA 424
Cdd:COG0115 221 IPVEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGR--PIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
139-389 |
1.90e-29 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 114.38 E-value: 1.90e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 139 QLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVDRDWVPdsagtslYVRPVLIGNEP 217
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 218 SLGVGSPT-HALLYVILCPVGAYFPGEALSPVSLLADPSFIRAwvggvgDCKiGGNYGPTVFVQKEAKKKGCEQVLwLYG 296
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 297 PDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFG 376
Cdd:pfam01063 141 EDGNVTEGSTSNVFLV---KGG--TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 927141679 377 SGTACQVCPVHRI 389
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
126-421 |
3.05e-126 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 366.52 E-value: 3.05e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 126 TLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTS 205
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 206 LYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGEaLSPVSLLADpSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKK 285
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKGG-EKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 286 KGCEQVLWLYGPDHELTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 365
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 927141679 366 LehgrvrEVFGSGTACQVCPVHRILYQGKFlhiPTMENGPELILRFYNELKMIQYG 421
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
78-431 |
6.66e-122 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 358.31 E-value: 6.66e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 78 EMTREPHKKPDPSEcLLFGKTFTDHMLMVEWNMEKgWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLF 157
Cdd:PRK13357 8 NPTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLF 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 158 RPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEVDRDWVPDSA-GTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPV 236
Cdd:PRK13357 86 RPDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVPPYGeGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 237 GAYFPGEAlSPVSLLADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIF-VFwt 314
Cdd:PRK13357 166 GAYFKGGV-KPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT-- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 315 hEDGaleLVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRALEHGRVREVFGSGTACQVCPVHRILYQGK 394
Cdd:PRK13357 243 -KDG---TVTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDK 317
|
330 340 350
....*....|....*....|....*....|....*....
gi 927141679 395 FLHIPTMENGPeLILRFYNELKMIQYGTKA--HEWMLQV 431
Cdd:PRK13357 318 EFVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
114-431 |
1.46e-93 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 284.34 E-value: 1.46e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 114 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVEV 193
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 194 DRDWVPDS-AGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGN 272
Cdd:TIGR01123 81 NKDWVPPYgSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKG-GLAPVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 273 YGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFvFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGeFR 351
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFF-FITG-DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 352 VTERKMTMNEFLRALEHGrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpELILRFYNELKMIQYGTKA--HEWML 429
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGDFEdpYGWIV 311
|
..
gi 927141679 430 QV 431
Cdd:TIGR01123 312 EV 313
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
132-415 |
7.44e-77 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 239.43 E-value: 7.44e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 132 SALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVdrdwvpdSAGTSLYVRP 210
Cdd:cd00449 2 RGLHYGDGVFEGLRAGKG-----RLFRLDEHLDRLNRSAKRLGLPiPYDREELREALKELVAA-------NNGASLYIRP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 211 VLIGNEPSLGVGSPTH--ALLYVILCPVGAYFPGeALSPVSLLADPSFIRAWVGGVGDCKIGGNYgPTVFVQKEAKKKGC 288
Cdd:cd00449 70 LLTRGVGGLGVAPPPSpePTFVVFASPVGAYAKG-GEKGVRLITSPDRRRAAPGGTGDAKTGGNL-NSVLAKQEAAEAGA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 289 EQVLWLYGPDHeLTEAGTMNIFVFWtheDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAleh 368
Cdd:cd00449 148 DEALLLDDNGY-VTEGSASNVFIVK---DG--ELVTPPLDGGILPGITRDSVIELAKELG-IKVEERPISLDELYAA--- 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 927141679 369 grvREVFGSGTACQVCPVHRILYQGKFlhiptMENGPELILRFYNEL 415
Cdd:cd00449 218 ---DEVFLTGTAAEVTPVTEIDGRGIG-----DGKPGPVTRKLRELL 256
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
114-424 |
5.11e-65 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 210.05 E-value: 5.11e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 114 WGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVE 192
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 193 VDRDwvpdsagTSLYVRPVLIGNEPSLGVGSPTH-ALLYVILCPVGAYFPGEALSPVSLLADPsFIRAWVGGVGDCKiGG 271
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEYePTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 272 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGe 349
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL---DTDgyVAEGSGSNVFIV---KDG--VLVTPPLSGGILPGITRDSVIELARELG- 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 927141679 350 FRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRIlyQGKflHIPTMENGPeLILRFYNELKMIQYGTKA 424
Cdd:COG0115 221 IPVEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGR--PIGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
95-394 |
4.44e-61 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 203.54 E-value: 4.44e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 95 FGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLC 174
Cdd:PLN02782 77 FGLVPTDYMYIMKCNRDGEFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENAIRMRNGAERMC 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 175 LPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLADP 254
Cdd:PLN02782 157 MPAPTVEQFVEAVKETVLANKRWVPPPGKGSLYIRPLLMGSGAVLGLAPAPEYTFLIYVSPVGNYFK-EGVAPINLIVEN 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 255 SFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLygpD--HE--LTEAGTMNIFVFwthEDGALElvTPALDGI 330
Cdd:PLN02782 236 EFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYL---DcvHKkyLEEVSSCNIFIV---KDNVIS--TPAIKGT 307
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 927141679 331 ILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGK 394
Cdd:PLN02782 308 ILPGITRKSIIDVARSQG-FQVEERNVTVDELLEA------DEVFCTGTAVVVSPVGSITYKGK 364
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
91-431 |
2.34e-53 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 182.05 E-value: 2.34e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 91 ECLLFGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSA 170
Cdd:PLN03117 23 EELGFALVPTDYMYVAKCKQGESFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQTGA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 171 LRLCLPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFpgEALSPVSL 250
Cdd:PLN03117 103 DRLCMTPPSLEQFVEAVKQTVLANKKWVPPPGKGTLYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYH--KASSGLNL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 251 LADPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWL-YGPDHELTEAGTMNIFVFwtheDGALeLVTPALDG 329
Cdd:PLN03117 181 KVDHKHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLdAATGKNIEELSACNIFIL----KGNI-VSTPPTSG 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 330 IILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGKFLHIPTMENGpeLIL 409
Cdd:PLN03117 256 TILPGVTRKSISELARDIG-YQVEERDVSVDELLEA------EEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEA--LST 326
|
330 340
....*....|....*....|....
gi 927141679 410 RFYNELKMIQYGTKAHE--WMLQV 431
Cdd:PLN03117 327 KLHLILTNIQMGVVEDKkgWMVEI 350
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
93-402 |
1.18e-46 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 165.28 E-value: 1.18e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 93 LLFGKTFTDHMLMVEWNMEKGWGRPRIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALR 172
Cdd:PLN02259 61 LGFGLNPADYMYVMKCSKDGEFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNAIRMKLGAER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 173 LCLPSFDKVELLECIRRLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLA 252
Cdd:PLN02259 141 MLMPSPSVDQFVNAVKQTALANKRWVPPAGKGTLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYFK-EGMAALNLYV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 253 DPSFIRAWVGGVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHE-LTEAGTMNIFVFwthedGALELVTPALDGII 331
Cdd:PLN02259 220 EEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSVKKKyLEEASSCNVFVV-----KGRTISTPATNGTI 294
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 927141679 332 LPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQGKFLHIPTME 402
Cdd:PLN02259 295 LEGITRKSVMEIASDQG-YQVVEKAVHVDEVMDA------DEVFCTGTAVVVAPVGTITYQEKRVEYKTGD 358
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
109-392 |
2.49e-46 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 164.12 E-value: 2.49e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 109 NMEKGWgrprIQPFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIR 188
Cdd:PLN02883 77 NFEQGY----LSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNAMRMKIGAERMCMHSPSVHQFIEGVK 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 189 RLVEVDRDWVPDSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCPVGAYFPgEALSPVSLLADPSFIRAWVGGVGDCK 268
Cdd:PLN02883 153 QTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYFK-EGTAALNLYVEEVIPRAYLGGTGGVK 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 269 IGGNYGPTVFVQKEAKKKGCEQVLWLYG-PDHELTEAGTMNIFVFWTHedgalELVTPALDGIILPGVVRQSLLDLARTW 347
Cdd:PLN02883 232 AISNYGPVLEVMRRAKSRGFSDVLYLDAdTGKNIEEVSAANIFLVKGN-----IIVTPATSGTILGGITRKSIIEIALDL 306
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 927141679 348 GeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRILYQ 392
Cdd:PLN02883 307 G-YKVEERRVPVEELKEA------EEVFCTGTAAGVASVGSITFK 344
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
139-389 |
1.90e-29 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 114.38 E-value: 1.90e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 139 QLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVDRDWVPdsagtslYVRPVLIGNEP 217
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 218 SLGVGSPT-HALLYVILCPVGAYFPGEALSPVSLLADPSFIRAwvggvgDCKiGGNYGPTVFVQKEAKKKGCEQVLwLYG 296
Cdd:pfam01063 69 GFGLPTSDpTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 297 PDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFG 376
Cdd:pfam01063 141 EDGNVTEGSTSNVFLV---KGG--TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 927141679 377 SGTACQVCPVHRI 389
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
121-389 |
8.64e-27 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 109.08 E-value: 8.64e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 121 PFQNLTLHPACSALHYSLQLFEGLKAYKGGDQRVrLFRPWLNMDRMLRSA--LRLCLPsFDKVELLECIRRLVEVDRdwv 198
Cdd:PRK06606 17 PWEDAKVHVLTHALHYGTGVFEGIRAYDTPKGPA-IFRLREHTKRLFNSAkiLRMEIP-YSVDELMEAQREVVRKNN--- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 199 PDSAgtslYVRP-VLIGNEpSLGV---GSPTHALLYVIlcPVGAYFPGEALSP-----VSlladpSFIRAWVGGV-GDCK 268
Cdd:PRK06606 92 LKSA----YIRPlVFVGDE-GLGVrphGLPTDVAIAAW--PWGAYLGEEALEKgirvkVS-----SWTRHAPNSIpTRAK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 269 IGGNYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLART 346
Cdd:PRK06606 160 ASGNYLNSILAKTEARRNGYDEALLL---DVEgyVSEGSGENIFIV---RDG--VLYTPPLTSSILEGITRDTVITLAKD 231
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 927141679 347 WGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 389
Cdd:PRK06606 232 LG-IEVIERRITRDELYIA------DEVFFTGTAAEVTPIREV 267
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
121-389 |
1.41e-23 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 100.13 E-value: 1.41e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 121 PFQNLTLHPACSALHYSLQLFEGLKAYKgGDQRVRLFRPWLNMDRMLRSALRLCLP-SFDKVELLECIRRLVEVdrdwvp 199
Cdd:TIGR01122 8 DWEDAKVHVLTHALHYGTGVFEGIRAYD-TDKGPAIFRLKEHIQRLYDSAKIYRMEiPYSKEELMEATRETLRK------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 200 dSAGTSLYVRPVLIGNEPSLGV----GSPTHalLYVILCPVGAYFPGEALSPVSLLADPSFIRAWVGGV-GDCKIGGNYG 274
Cdd:TIGR01122 81 -NNLRSAYIRPLVFRGDGDLGLnpraGYKPD--VIIAAWPWGAYLGEEALEKGIDAKVSSWRRNAPNTIpTAAKAGGNYL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 275 PTVFVQKEAKKKGCEQVLWLyGPDHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTE 354
Cdd:TIGR01122 158 NSLLAKSEARRHGYDEAILL-DVEGYVAEGSGENIFIV---KDG--VLFTPPVTSSILPGITRDTVITLAKELG-IEVVE 230
|
250 260 270
....*....|....*....|....*....|....*
gi 927141679 355 RKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 389
Cdd:TIGR01122 231 QPISREELYTA------DEAFFTGTAAEITPIREV 259
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
141-389 |
1.96e-18 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 84.57 E-value: 1.96e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 141 FEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLPS-FDKVELLECIRRLVEvdRDWVPDSAGtslYVRpVLIGNEP-S 218
Cdd:cd01558 28 YEVIRVYNG-----KPFALDEHLDRLYRSAKELRIDIpYTREELKELIRELVA--KNEGGEGDV---YIQ-VTRGVGPrG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 219 LGVGSPTHALLYVILCPVGAYFPGEALSPVSLLADPsFIRaWvggvGDCKI-GGNYGPTVFVQKEAKKKGCEQVlWLYGP 297
Cdd:cd01558 97 HDFPKCVKPTVVIITQPLPLPPAELLEKGVRVITVP-DIR-W----LRCDIkSLNLLNNVLAKQEAKEAGADEA-ILLDA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 298 DHELTEAGTMNIFVFwthEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGS 377
Cdd:cd01558 170 DGLVTEGSSSNVFIV---KNG--VLVTPPLDNGILPGITRATVIELAKELG-IPVEERPFSLEELYTA------DEVFLT 237
|
250
....*....|..
gi 927141679 378 GTACQVCPVHRI 389
Cdd:cd01558 238 STTAEVMPVVEI 249
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
133-389 |
2.51e-14 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 72.34 E-value: 2.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 133 ALHYSLQLFEGLKAYKGgdqRVRLFRPWLnmDRMLRSALRLCLPSFDKVELLeciRRLVEVDRDWVPDSAGTSL-YVRPV 211
Cdd:cd01559 3 GFAYGDGVFETMRALDG---RLFLLDAHL--ARLERSARRLGIPEPDLPRLR---AALESLLAANDIDEGRIRLiLSRGP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 212 LIGNEPSLGVGSPTHaLLYVILCPVGAYFPGEALSPVSL-LADPSFIrawvGGVGDCkiggNYGPTVFVQKEAKKKGCEQ 290
Cdd:cd01559 75 GGRGYAPSVCPGPAL-YVSVIPLPPAWRQDGVRLITCPVrLGEQPLL----AGLKHL----NYLENVLAKREARDRGADE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 291 VLWLyGPDHELTEAGTMNifVFWTHeDGalELVTPALDGIILPGVVRQSLLDLARTWGEfRVTERKMTMNEFLRAlehgr 370
Cdd:cd01559 146 ALFL-DTDGRVIEGTASN--LFFVK-DG--ELVTPSLDRGGLAGITRQRVIELAAAKGY-AVDERPLRLEDLLAA----- 213
|
250
....*....|....*....
gi 927141679 371 vREVFGSGTACQVCPVHRI 389
Cdd:cd01559 214 -DEAFLTNSLLGVAPVTAI 231
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
141-394 |
1.36e-11 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 64.89 E-value: 1.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 141 FEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCL-PSFDKVELLECIRRLVEVD--RDwvpdsagtsLYVRPVLignep 217
Cdd:PRK08320 33 FEGIRAYNG-----RVFRLKEHIDRLYDSAKAIMLeIPLSKEEMTEIVLETLRKNnlRD---------AYIRLVV----- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 218 SLGVGS----------PThalLYVILCPVGAYfPGEaLSPVSLLADPSFIRAWVGGVGDCKIGG-NYGPTVFVQKEAKKK 286
Cdd:PRK08320 94 SRGVGDlgldprkcpkPT---VVCIAEPIGLY-PGE-LYEKGLKVITVSTRRNRPDALSPQVKSlNYLNNILAKIEANLA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 287 GCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGALelVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLR 364
Cdd:PRK08320 169 GVDEAIML---NDEgyVAEGTGDNIFIV---KNGKL--ITPPTYAGALEGITRNAVIEIAKELG-IPVREELFTLHDLYT 239
|
250 260 270
....*....|....*....|....*....|....
gi 927141679 365 AlehgrvREVFGSGTACQVCPV----HRILYQGK 394
Cdd:PRK08320 240 A------DEVFLTGTAAEVIPVvkvdGRVIGDGK 267
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
121-389 |
1.85e-09 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 58.45 E-value: 1.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 121 PFQNLTLHPACSALHYSLQLFEGLKAYKGgdqrvRLFRPWLNMDRMLRSALRLCLPSFDKVELLECIRRLVeVDRDWVPD 200
Cdd:PRK07544 19 PWRDAKVHVLTHGLHYASSVFEGERAYGG-----KIFKLREHSERLRRSAELLDFEIPYSVAEIDAAKKET-LAANGLTD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 201 SagtslYVRPVLIGNEPSLGVGSPTHALLYVILC-PVGAYFPGEA-LSPVSL-LA-----DPSFIRAwvggvgDCKIGGN 272
Cdd:PRK07544 93 A-----YVRPVAWRGSEMMGVSAQQNKIHLAIAAwEWPSYFDPEAkMKGIRLdIAkwrrpDPETAPS------AAKAAGL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 273 YGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIFVFwthEDGALElvTPALDgIILPGVVRQSLLDLARTWGeF 350
Cdd:PRK07544 162 YMICTISKHAAEAKGYADALML---DYRgyVAEATGANIFFV---KDGVIH--TPTPD-CFLDGITRQTVIELAKRRG-I 231
|
250 260 270
....*....|....*....|....*....|....*....
gi 927141679 351 RVTERKMtMNEFLRALEhgrvrEVFGSGTACQVCPVHRI 389
Cdd:PRK07544 232 EVVERHI-MPEELAGFS-----ECFLTGTAAEVTPVSEI 264
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
161-389 |
2.48e-07 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 51.88 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 161 LNMDRMLRSALRLCL-PSFDKVEL----LECIRRLvevdrdwvpdSAGTSLYVRPVLIGNEPSLGVGSPTHALLYVILCP 235
Cdd:PRK13356 52 LHCARVNRSAEALGLkPTVSAEEIealaREGLKRF----------DPDTALYIRPMYWAEDGFASGVAPDPESTRFALCL 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 236 VGAYFPGEALSPVSLladPSFIRAWVG-GVGDCKIGGNYGPTVFVQKEAKKKGCEQVLWLYGPDHeLTEAGTMNIFVFwt 314
Cdd:PRK13356 122 EEAPMPEPTGFSLTL---SPFRRPTLEmAPTDAKAGCLYPNNARALREARSRGFDNALVLDMLGN-VAETATSNVFMV-- 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 927141679 315 hEDGalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 389
Cdd:PRK13356 196 -KDG--VVFTPVPNGTFLNGITRQRVIALLREDG-VTVVETTLTYEDFLEA------DEVFSTGNYSKVVPVTRF 260
|
|
| PRK12400 |
PRK12400 |
D-amino acid aminotransferase; Reviewed |
134-386 |
7.37e-07 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 171470 Cd Length: 290 Bit Score: 50.40 E-value: 7.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 134 LHYSLQLFEGLKAYKGGdqrVRLFRPwlNMDRMLRS--ALRLCLPsFDKVELLECIRRLVEvDRDWVPDsaGTsLYVrpv 211
Cdd:PRK12400 30 LQFGDGVYEVIRLYKGN---FHLLDP--HITRLYRSmeEIELTLP-FSKAELITLLYKLIE-NNNFHED--GT-IYL--- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 212 lignEPSLGVGSPTHALLYVILCPVGAYfpgealspVSLLADPSF-----IRA-------WVggvgDCKIGG-NYGPTVF 278
Cdd:PRK12400 97 ----QVSRGVQARTHTFSYDVPPTIYAY--------ITKKERPALwieygVRAisepdtrWL----RCDIKSlNLLPNIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 279 VQKEAKKKGCEQVLWLYgpDHELTEAGTMNIFVFwthEDGALeLVTPAlDGIILPGVVRQSLLDLARTWgEFRVTERKMT 358
Cdd:PRK12400 161 AATKAERKGCKEALFVR--NGTVTEGSHSNFFLI---KNGTL-YTHPA-NHLILNGIIRQYVLSLAKTL-RIPVQEELFS 232
|
250 260
....*....|....*....|....*...
gi 927141679 359 MNEFLRAlehgrvREVFGSGTACQVCPV 386
Cdd:PRK12400 233 VRDVYQA------DECFFTGTTIEILPM 254
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
275-389 |
9.11e-06 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 47.23 E-value: 9.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 275 PTVFVQKEAKKKGCeQVLWLYGpDHELTEAGTMNIFVfwTHEDGALelVTPALDGIILPGVVRQSLLDLARTWGeFRVTE 354
Cdd:PRK06680 155 PNVLAKQAAKEAGA-QEAWMVD-DGFVTEGASSNAWI--VTKDGKL--VTRPADNFILPGITRHTLIDLAKELG-LEVEE 227
|
90 100 110
....*....|....*....|....*....|....*
gi 927141679 355 RKMTMNEFLRAlehgrvREVFGSGTACQVCPVHRI 389
Cdd:PRK06680 228 RPFTLQEAYAA------REAFITAASSFVFPVVQI 256
|
|
| PRK07849 |
PRK07849 |
aminodeoxychorismate lyase; |
141-365 |
7.17e-05 |
|
aminodeoxychorismate lyase;
Pssm-ID: 236114 [Multi-domain] Cd Length: 292 Bit Score: 44.56 E-value: 7.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 141 FEGLKAYKGgdqRVRLFRPWLnmDRMLRSALRLCLPSFDkvelLECIRRLVE-VDRDWvpDSAGTSLYVRPVLignepSL 219
Cdd:PRK07849 42 FETLLVRDG---RPCNLEAHL--ERLARSAALLDLPEPD----LDRWRRAVElAIEEW--RAPEDEAALRLVY-----SR 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 220 GVGSPTHALLYVILCPVGAYFPGEALSPVSLLADPsfiRAWVGGVGDCK---IGG----NYGPTVFVQKEAKKKGCEQVL 292
Cdd:PRK07849 106 GRESGGAPTAWVTVSPVPERVARARREGVSVITLD---RGYPSDAAERApwlLAGaktlSYAVNMAALRYAARRGADDVI 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 927141679 293 WLyGPDHELTEAGTMNifVFWTHEDgalELVTPALDGIILPGVVRQSLLDLARTWGeFRVTERKMTMNEFLRA 365
Cdd:PRK07849 183 FT-STDGYVLEGPTST--VVIATDD---RLLTPPPWYGILPGTTQAALFEVAREKG-WDCEYRALRPADLFAA 248
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
272-367 |
2.31e-04 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 43.08 E-value: 2.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 927141679 272 NYGPTVFVQKEAKKKGCEQVLWLygpDHE--LTEAGTMNIfVFWTHEDgalELVTPALDGiILPGVVRQSLLDLA---RT 346
Cdd:PLN02845 188 NYLPNALSQMEAEERGAFAGIWL---DEEgfVAEGPNMNV-AFLTNDG---ELVLPPFDK-ILSGCTARRVLELAprlVS 259
|
90 100
....*....|....*....|..
gi 927141679 347 WGEFR-VTERKMTMNEFLRALE 367
Cdd:PLN02845 260 PGDLRgVKQRKISVEEAKAADE 281
|
|
| |
