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Conserved domains on  [gi|2024359624|ref|XP_015130676|]
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CAP-Gly domain-containing linker protein 1 isoform X11 [Gallus gallus]

Protein Classification

CAP-Gly domain-containing linker protein; CAP-Gly domain-containing protein( domain architecture ID 13652022)

CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth| CAP (cytoskeleton-associated protein)-Gly domain-containing protein similar to Schizosaccharomyces pombe Tip elongation protein 1 that has a role in stabilizing and targeting the growing tips of the microtubules along the long axis of the cell, directing them to the ends of the cell

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.23e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.23e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 659-1483 9.34e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 9.34e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  659 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 719
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  720 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 788
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 868
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  869 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 942
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  943 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1015
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1079
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1080 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1143
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1144 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1223
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1224 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1303
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1304 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1377
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1378 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1454
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359624 1455 KKSLENAFSDMKREQELDFSAKRLLVQEN 1483
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1309-2025 2.35e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.35e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1380
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1381 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1460
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1461 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1540
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1541 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1620
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1621 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1700
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1701 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1763
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1764 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1809
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1810 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1889
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1890 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1969
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1970 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2025
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-814 3.16e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 3.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrdghDRHVLEMEAKMDQLRA 416
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRL--ESSKHI 494
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEeeEEEALE 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  495 DDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENS-- 572
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAga 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  573 -DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALK 651
Cdd:COG1196    526 vAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  652 AKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVKELD----------VLQAKCNEQTKLIGSLTQQI 721
Cdd:COG1196    605 ASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsaggslTGGSRRELLAALLEAEAELE 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  722 RASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK 801
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          490
                   ....*....|...
gi 2024359624  802 DSLEKELQLLKEK 814
Cdd:COG1196    763 EELERELERLERE 775
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2149-2165 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359624 2149 RPYCDTCEMFGHWTADC 2165
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2109-2126 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359624 2109 RLFCDICGCFDlHDTEDC 2126
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.23e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.23e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.61e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.61e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.87e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.87e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 659-1483 9.34e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 9.34e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  659 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 719
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  720 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 788
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 868
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  869 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 942
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  943 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1015
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1079
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1080 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1143
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1144 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1223
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1224 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1303
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1304 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1377
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1378 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1454
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359624 1455 KKSLENAFSDMKREQELDFSAKRLLVQEN 1483
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1309-2025 2.35e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.35e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1380
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1381 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1460
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1461 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1540
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1541 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1620
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1621 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1700
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1701 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1763
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1764 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1809
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1810 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1889
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1890 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1969
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1970 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2025
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 805-1655 6.47e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 87.72  E-value: 6.47e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  805 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 883
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  884 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 961
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  962 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1041
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1042 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1121
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1122 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1201
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1202 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1274
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1275 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1354
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1355 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1434
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1435 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1513
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1514 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1593
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624 1594 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1655
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1021-1665 1.05e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1021 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1097
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1098 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1177
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1178 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1257
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1258 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1337
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1338 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1417
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1418 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1495
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1496 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1575
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1576 NMKENLTVEKKARILDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1655
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024359624 1656 EQLASKIEQL 1665
Cdd:COG1196    770 ERLEREIEAL 779
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.70e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.70e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1309-1987 6.91e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 6.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1385
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1386 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1460
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1461 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1538
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1539 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1599
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1600 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1670
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1671 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1747
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1748 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1823
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1824 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1891
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1892 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1952
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359624 1953 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1987
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1729-2028 7.97e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.97e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1729 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1808
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1809 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1888
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1889 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1968
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1969 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2028
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1164 8.58e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.86  E-value: 8.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  335 GLLTETSSRYARKISGTTALQEALK--EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDGHDRHVLEMEAKMD 412
Cdd:PTZ00121  1098 GKAEEAKKTETGKAEEARKAEEAKKkaEDARKAEEARKAEDARKAEEARK----AEDAKRVEIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  413 QLRAMVEAADREKVELLNQLE--EEKRKVEDLQFRVEEESITkgdlEVATVSEKSRIMElerdlalrVKEVAELRGRLES 490
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRkaEDARKAEAARKAEEERKAE----EARKAEDAKKAEA--------VKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  491 SKHIDDVDTSlsllQEISSLQEKMAAagkEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKEneslKTKLDHANKE 570
Cdd:PTZ00121  1242 AKKAEEERNN----EEIRKFEEARMA---HFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE----KKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  571 nsdvielwksklesaiASHQQAMEELKvsfnkgvgaQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEAL 650
Cdd:PTZ00121  1311 ----------------AEEAKKADEAK---------KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  651 KAKLLEVTEEKEQTLENLKAKLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLD 730
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKAEEKK-----KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  731 LAALQKANSEGKLEIQKLSEQL--QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKEl 808
Cdd:PTZ00121  1441 EEAKKADEAKKKAEEAKKAEEAkkKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE- 1519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  809 qllKEKFTSAVDGAENAQRAmqETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQL---TEAKVKLENDI 885
Cdd:PTZ00121  1520 ---EAKKADEAKKAEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaEEAKKAEEARI 1594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  886 AEIMKSSGDSS---AQLMKMNDELRLKERQL----------EQIQLELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLK 950
Cdd:PTZ00121  1595 EEVMKLYEEEKkmkAEEAKKAEEAKIKAEELkkaeeekkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEeaKKAEEDK 1674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  951 THQEELKKMQDQLTDMKKQMETSQNQYKDLQaKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQ---KKNDELETQA 1027
Cdd:PTZ00121  1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEedkKKAEEAKKDE 1753

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1028 EELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEME-------SKILLVQQDR 1100
Cdd:PTZ00121  1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEgnlvindSKEMEDSAIK 1833

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1101 EELWTKNEELNsENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETA-QADLLKITQEND 1164
Cdd:PTZ00121  1834 EVADSKNMQLE-EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIeEADEIEKIDKDD 1897
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1610-2024 3.09e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.86  E-value: 3.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1610 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1689
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1690 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1769
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1770 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1849
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1850 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1924
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1925 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2004
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359624 2005 LESDKLKLEEKVKNLEQKLK 2024
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.09e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.09e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-814 3.16e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 3.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrdghDRHVLEMEAKMDQLRA 416
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRL--ESSKHI 494
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEeeEEEALE 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  495 DDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENS-- 572
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAga 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  573 -DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALK 651
Cdd:COG1196    526 vAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  652 AKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVKELD----------VLQAKCNEQTKLIGSLTQQI 721
Cdd:COG1196    605 ASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsaggslTGGSRRELLAALLEAEAELE 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  722 RASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK 801
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          490
                   ....*....|...
gi 2024359624  802 DSLEKELQLLKEK 814
Cdd:COG1196    763 EELERELERLERE 775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
423-890 1.02e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 1.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  423 REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDV----- 497
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKaeeyi 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  498 ------DTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEE--ALRKEIKTLSASNERMGKENESLKTKLDHANK 569
Cdd:PRK03918   297 klsefyEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEElkKKLKELEKRLEELEERHELYEEAKAKKEELER 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  570 ENSDVIELWKSKLESAIASHQQAMEELKVSFNK---GVGAQTAEFAELKTQMEKVK-LDYENEMSNLKLKQENEK---SQ 642
Cdd:PRK03918   377 LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKitaRIGELKKEIKELKKAIEELKkAKGKCPVCGRELTEEHRKellEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  643 HLKEIEALKAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IG 715
Cdd:PRK03918   457 YTAELKRIEKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLI 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  716 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLS 795
Cdd:PRK03918   536 KLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEK 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  796 AVNQVKDSLEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 873
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREE 691

                          490
                   ....*....|....*..
gi 2024359624  874 LTEAKVKLENDIAEIMK 890
Cdd:PRK03918   692 IKKTLEKLKEELEEREK 708
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2149-2165 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359624 2149 RPYCDTCEMFGHWTADC 2165
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 519-675 7.13e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.10  E-value: 7.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  519 KEHQREMSSLKEKFE---SSEEALRKEIKTLSASNERM---GKENESLKTKLDHANKENSDVIELWK------SKLESAI 586
Cdd:pfam05667  331 QQREEELEELQEQLEdleSSIQELEKEIKKLESSIKQVeeeLEELKEQNEELEKQYKVKKKTLDLLPdaeeniAKLQALV 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  587 ASHQQAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyenemsnlKLKQENEKSQHLKEIEALKAKLLEVTEE---KEQ 663
Cdd:pfam05667  411 DASAQRLVELAGQWEKHRVPLIEEYRALKEA---------------KSNKEDESQRKLEEIKELREKIKEVAEEakqKEE 475

                          170
                   ....*....|..
gi 2024359624  664 TLENLKAKLESV 675
Cdd:pfam05667  476 LYKQLVAEYERL 487
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2109-2126 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359624 2109 RLFCDICGCFDlHDTEDC 2126
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 716-995 1.11e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  716 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 795
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  796 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 870
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  871 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 948
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359624  949 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 995
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.23e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.23e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.61e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.61e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.87e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.87e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 659-1483 9.34e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.61  E-value: 9.34e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  659 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 719
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  720 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 788
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 868
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  869 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 942
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  943 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1015
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1079
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1080 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1143
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1144 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1223
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1224 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1303
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1304 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1377
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1378 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1454
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359624 1455 KKSLENAFSDMKREQELDFSAKRLLVQEN 1483
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 406-1235 3.33e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 3.33e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLalrvKEVAELR 485
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL----EELEAQL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  486 GRLESSKhiDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLD 565
Cdd:TIGR02168  326 EELESKL--DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  566 HANKENSDvIELWKSKLESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQEneksqhlk 645
Cdd:TIGR02168  404 RLEARLER-LEDRRERLQQEIEELLKKLEEAELK------ELQAELEELEEELEELQEELERLEEALEELRE-------- 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  646 EIEALKAKLLEvTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTK--------LIGSL 717
Cdd:TIGR02168  469 ELEEAEQALDA-AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRL 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  718 TQQIRASEEKLLDLAALQKANSEGKLEIQKLSeqlQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAV 797
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFLKQNELGRVTFLPLD---SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  798 NQVKDSLEKELQLLKEK------FT----------SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVME 861
Cdd:TIGR02168  625 VLVVDDLDNALELAKKLrpgyriVTldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  862 TKLkereereQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTaqka 941
Cdd:TIGR02168  705 KEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA---- 773

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  942 eqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfKQNLLDAEEALKAAQKKND 1021
Cdd:TIGR02168  774 ----EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL---------------NEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1022 ELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1097
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSedieSLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1098 QDREELWTKNEELNsENKKILKQKEA--AEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQ 1175
Cdd:TIGR02168  915 RELEELREKLAQLE-LRLEGLEVRIDnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIE 993

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1176 QLKELQANKDAVDvacqkhiKEREELEHYQKLLEEndrVIKDKDDVI-QRLQSSYDDLARN 1235
Cdd:TIGR02168  994 EYEELKERYDFLT-------AQKEDLTEAKETLEE---AIEEIDREArERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1309-2025 2.35e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.35e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1380
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1381 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1460
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1461 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1540
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1541 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1620
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1621 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1700
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1701 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1763
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1764 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1809
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1810 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1889
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1890 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1969
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1970 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2025
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 358-1038 4.65e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 4.65e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  358 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHdrhvLEMEAKMDQLRAMVEAAdrekVELLNQLEEEKR 437
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYAL----ANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  438 KvedLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKhiDDVDTSLSLLQEISSLQEKMAAA 517
Cdd:TIGR02168  306 I---LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE--AELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  518 GKEHQREMSSLKEKFESSE---EALRKEIKTLSASNERMGKENESLKTKLDHANKE----NSDVIELWKSKLESAIASHQ 590
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNneiERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaELEELEEELEELQEELERLE 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  591 QAMEELKVSFNKGVGAQTA---EFAELKTQMEKVKLDYENEMSNLKLKQENEKSQH-LKEIEALKAKLLEVTEEKEQTLE 666
Cdd:TIGR02168  461 EALEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSgLSGILGVLSELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  667 nlkAKLESVEDQHLVEMEDTLNKLQEA--EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLE 744
Cdd:TIGR02168  541 ---AALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  745 IQKLSEQL-------QAAEKQIQNLETEK---------------VGGSSKVSNLT----KELQGKEQKLLDLEKNLSAVN 798
Cdd:TIGR02168  618 LSYLLGGVlvvddldNALELAKKLRPGYRivtldgdlvrpggviTGGSAKTNSSIlerrREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  799 QVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAK 878
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  879 VKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKK 958
Cdd:TIGR02168  778 AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ-IEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  959 MQDQLTDMKKQMETSQNQYKDLQAKYEketsemitKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK 1038
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERA--------SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 862-1739 9.15e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 9.15e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  862 TKLKER-EEREQQLTEAKVKLE--NDIAEIMKSSGDS-SAQLMKMNDELRLKErQLEQIQLELTKAneKAVQLQKNVEQT 937
Cdd:TIGR02168  168 SKYKERrKETERKLERTRENLDrlEDILNELERQLKSlERQAEKAERYKELKA-ELRELELALLVL--RLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  938 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSE------MITKHDADIKGFKQNLLDAEE 1011
Cdd:TIGR02168  245 QEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrleqQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1012 ALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1087
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1088 EMESKILLVQQDREELWTKNEELNsenkkilkqKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1167
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELL---------KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1168 SSESTLLQQLKELQANKDAVDVACQKHIKERE---ELEHYQKLLEENDRVIKDKDDVIQR--------LQSSYDDLA-RN 1235
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRLQAVVvEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1236 QRELLQEVSILTAERDS-------AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQA 1308
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKdEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLAEREELvnen 1388
Cdd:TIGR02168  635 LELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE--LEEKIEELEEKIAELEKALAELRKEL---- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1389 kavtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1468
Cdd:TIGR02168  708 ----EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1469 QEldfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1548
Cdd:TIGR02168  784 IE--------------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1549 CSSDIEILNRERTELQDKCQKLTGEVENMKEnltvekkarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE 1628
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1629 LLVQEKEKSETKLEEvikekmilyketeqLASKIEQLKSDFTSLsvskaeledvhscVSVMLDELQHKYEVTEKEKMELV 1708
Cdd:TIGR02168  919 ELREKLAQLELRLEG--------------LEVRIDNLQERLSEE-------------YSLTLEEAEALENKIEDDEEEAR 971

                          890       900       910
                   ....*....|....*....|....*....|.
gi 2024359624 1709 QENESLHAEWKSLVIINEEILKEKEKLSKEY 1739
Cdd:TIGR02168  972 RRLKRLENKIKELGPVNLAAIEEYEELKERY 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 905-1799 1.03e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 90.51  E-value: 1.03e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  905 ELRLKERQLEQIQLELTKANEKAVQLQKNVEqtaqKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 984
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRRERE----KAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  985 EKETSEmitkhdadikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAE-QAKSLSSVLASARKEIELMSDKMRDLIS 1063
Cdd:TIGR02169  254 EKLTEE------------------ISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1064 EKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1143
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1144 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQ 1223
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1224 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSRE-ELCVSLANT 1302
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1303 ANENQA--------LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASE 1374
Cdd:TIGR02169  553 VVEDDAvakeaielLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1375 QRLLAERE------ELVNENKAVTEKLTKATADAVLAeTAFTEKINELNLEKESVfskslqfEKHNEALLREKDELERKY 1448
Cdd:TIGR02169  633 RRLMGKYRmvtlegELFEKSGAMTGGSRAPRGGILFS-RSEPAELQRLRERLEGL-------KRELSSLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1449 SELLDEKKSLENAFSDMKREQELdfsakrlLVQENTTLKYSIEALEEELKKKNlenQELIACRSDLSDLLKEAQDARRTL 1528
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1529 ENELAAVSHAKQVLSSSFntcssdIEILNRERTELQDKCQKLTGEVENMKenltvekkaRILDKESFLLErmelqnnigF 1608
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSR------IPEIQAELSKLEEEVSRIEARLREIE---------QKLNRLTLEKE---------Y 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1609 LEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSV 1688
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1689 MLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEIL------KEKEKLSKEYYKLhEKVVALLEQTDADFSCRLL 1762
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqAELQRVEEEIRAL-EPVNMLAIQEYEEVLKRLD 989

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 2024359624 1763 VSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEA 1799
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1022-1876 2.52e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.52e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1022 ELETQAEELKKQAEQA---KSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKI 1093
Cdd:TIGR02168  197 ELERQLKSLERQAEKAeryKELKAELRELELALLVLRleelrEELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1094 LLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQestekvalisekskLLSEIETAQADLLKITQENDALRSSESTL 1173
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLAN--------------LERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1174 LQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLaRNQRELLQevsiltaerdsa 1253
Cdd:TIGR02168  343 EEKLEELKEELES----------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL-ELQIASLN------------ 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1254 qekdldlksthialkNEIDCLLQTNRSLQSEKEMLLKSREELcvslantanENQALKLRKDEMQTELETEREKLEKMTKD 1333
Cdd:TIGR02168  400 ---------------NEIERLEARLERLEDRRERLQQEIEEL---------LKKLEEAELKELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1334 NMDLKASLSSLSNFLEEMKSSREASNSEKIHLlqEALFASEQRLLAEREELVNENKAVT-EKLTKATADAVLAETAFTEk 1412
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQENLEGFSEGVKALLkNQSGLSGILGVLSELISVD- 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1413 iNELNLEKESVFSKSLQfekhneALLREKDELERKYSELLDEKKSLENAFS--DMKREQELDFSAKRLLVQENTTLKYSI 1490
Cdd:TIGR02168  533 -EGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1491 EALEEELKKKNLENQELIACRsdLSDLLKEAQDARRTLENELAAVSHAKQVLSSSF-------NTCSSD------IEILN 1557
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVL--VVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSIlerrreIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1558 RERTELQDKCQKLTGEVENMKENLT-VEKKARILDKESFLLERM--ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK 1634
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEeLEEELEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1635 EKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESL 1714
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1715 HAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvSEGKHELLLEEMSNLALKLREIERlqaqtfm 1794
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS--------LEEALALLRSELEELSEELRELES------- 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1795 QKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE 1874
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982


                   ..
gi 2024359624 1875 EL 1876
Cdd:TIGR02168  983 EL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 353-1075 2.94e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.94e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLE---MEAKMDQLRAMVEAADREKVELL 429
Cdd:TIGR02168  243 ELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrLEQQKQILRERLANLERQLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  430 NQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLES-SKHIDDVDTSLSLLQ-EI 507
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETlRSKVAQLELQIASLNnEI 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  508 SSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIA 587
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  588 SHQQA---------MEELKVSFNKGVGAQTAEFAELKTQME------KVKLDYENEMSNL-----------KLKQENEKS 641
Cdd:TIGR02168  483 ELAQLqarldslerLQENLEGFSEGVKALLKNQSGLSGILGvlseliSVDEGYEAAIEAAlggrlqavvveNLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  642 QHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQH------LVEMEDTLNK--------------LQEAEIKVKELD 701
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFlgvakdLVKFDPKLRKalsyllggvlvvddLDNALELAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  702 VLQAKCNEQTKLI---GSLTQQIRASEEKLL----DLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVS 774
Cdd:TIGR02168  643 PGYRIVTLDGDLVrpgGVITGGSAKTNSSILerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  775 NLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLK 854
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR 802

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  855 SNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV 934
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  935 EqtaqkaeqSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNL-----LDA 1009
Cdd:TIGR02168  883 A--------SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL-ELRLEGLEVRIDNLQERLseeysLTL 953

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624 1010 EEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1075
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETL 1019
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 805-1655 6.47e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 87.72  E-value: 6.47e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  805 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 883
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  884 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 961
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  962 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1041
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1042 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1121
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1122 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1201
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1202 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1274
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1275 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1354
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1355 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1434
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1435 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1513
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1514 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1593
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624 1594 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1655
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1021-1665 1.05e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.05e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1021 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1097
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1098 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1177
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1178 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1257
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1258 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1337
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1338 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1417
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1418 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1495
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1496 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1575
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1576 NMKENLTVEKKARILDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1655
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024359624 1656 EQLASKIEQL 1665
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 992-1885 2.52e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.89  E-value: 2.52e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  992 ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAkslssvlasarkeielmsDKMRDLISEKEtlaqe 1071
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA------------------ERYQALLKEKR----- 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1072 rntlKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEkskllsEIET 1151
Cdd:TIGR02169  222 ----EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLR 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1152 AQADLLKITQENDALRSSESTLLQQLKELQAnkdavdvacqKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD 1231
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEE----------RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1232 LARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKL 1311
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1312 RKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMkssreasnSEKIHLLQEALFASEQRLLAEREElVNENKAV 1391
Cdd:TIGR02169  442 EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV--------EKELSKLQRELAEAEAQARASEER-VRGGRAV 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1392 TE--------------KLTKATADAVLA-ETAFTEKINELNLEKESVFSKSLQFEKHNEA-----LLREKDELERKYSEL 1451
Cdd:TIGR02169  513 EEvlkasiqgvhgtvaQLGSVGERYATAiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1452 LDEKKSLENAFSDMKREQEldFSAKRLLVQENTTLKYSIEAleeelKKKNLENQELIACRSDL----------SDLLKEA 1521
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPK--YEPAFKYVFGDTLVVEDIEA-----ARRLMGKYRMVTLEGELfeksgamtggSRAPRGG 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1522 QDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTvekkaRILDKESFLLERME 1601
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE-----QLEQEEEKLKERLE 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1602 -LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVikEKMILYKETEQLASKIEQLKSDFTSLSVSKAELE 1680
Cdd:TIGR02169  741 eLEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1681 dvhscvsVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALleqtdadfscr 1760
Cdd:TIGR02169  819 -------QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL----------- 880

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1761 llvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIH------QEKIETLASLENS 1834
Cdd:TIGR02169  881 ----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedEEIPEEELSLEDV 956

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1835 RQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKL 1885
Cdd:TIGR02169  957 QAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 429-1183 2.60e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.60e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  429 LNQLEEEKRKVEDLQFRVEEESITKGDLEVAtvseksRIMELERDLALRVKEVAELRGRLES-SKHIDDVDTSLSLLQ-E 506
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAELRELELALLVL------RLEELREELEELQEELKEAEEELEElTAELQELEEKLEELRlE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  507 ISSLQEKMAAAGKEHQrEMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKEnsdvIELWKSKLESAI 586
Cdd:TIGR02168  276 VSELEEEIEELQKELY-ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE----LAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  587 ASHQQAMEELKvsfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHlKEIEALKAKLLEVTEEKEQTLE 666
Cdd:TIGR02168  351 EELESLEAELE--------ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-NEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  667 NLKAKLESVEDQHLVEMEDTLNKL-QEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEI 745
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELeEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  746 QKLSEqlqaAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKL-LDLEKNLSAVnqVKDSLEKELQ----LLKEKFTSAVD 820
Cdd:TIGR02168  502 EGFSE----GVKALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAV--VVENLNAAKKaiafLKQNELGRVTF 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  821 GAENAQRAMQETINKLNQKEEQFALMSSELEQLKS------------NLTVMETKLKEREEREQQLT--EAKVKLENDIA 886
Cdd:TIGR02168  576 LPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFdpklrkalsyllGGVLVVDDLDNALELAKKLRpgYRIVTLDGDLV 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  887 eimKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDM 966
Cdd:TIGR02168  656 ---RPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEE-LEQLRKELEELSRQISAL 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  967 KKQMETSQNQYKDLQAKYEKETSEmITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKkqaEQAKSLSSVLAS 1046
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKE-LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLK---EELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1047 ARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEA 1126
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE 887

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1127 KSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQAN 1183
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 684-1333 4.68e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 4.68e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  684 EDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRA--------SEEKLLDLAALqkansegKLEIQKLSEQLQAA 755
Cdd:COG1196    175 EEAERKLEATE---ENLERLEDILGELERQLEPLERQAEKaeryrelkEELKELEAELL-------LLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  756 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 835
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  836 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 915
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  916 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDmKKQMETSQNQYKDLQAKYEKETSEMITKH 995
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL-EEEEEALLELLAELLEEAALLEAALAELL 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  996 DADIKgfkqnlLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARK---------EIELMSDKMRDLISEKE 1066
Cdd:COG1196    484 EELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaalEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1067 TLAQERNTLKLEKE-----------------SLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSR 1129
Cdd:COG1196    558 VAAAAIEYLKAAKAgratflpldkiraraalAAALARGAIGAAVDLVASDLREA----DARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1130 QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLE 1209
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1210 ENDRviKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthiALKNEIdcllqtnRSLQSEKEML- 1288
Cdd:COG1196    714 EERL--EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE----ELEREL-------ERLEREIEALg 780

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1289 ---LKSREELcvslantanenQALKLRKDEMQTE---LETEREKLEKMTKD 1333
Cdd:COG1196    781 pvnLLAIEEY-----------EELEERYDFLSEQredLEEARETLEEAIEE 820
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 354-1009 9.31e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.31e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  354 LQEALKEKQQHIEQLLAERDLERAEVAKATshvgEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLE 433
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLE 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  434 EEKRKVEDLQFRVEEESITKGDLEVATVSEksRIMELERDLALRVKEVAELRGRLESskhiddvdtslsLLQEISSLQEK 513
Cdd:TIGR02168  411 RLEDRRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEE------------LREELEEAEQA 476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  514 MAAAGKEHQREMSSLK--EKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKensdvielWKSKLESAIASHQQ 591
Cdd:TIGR02168  477 LDAAERELAQLQARLDslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEG--------YEAAIEAALGGRLQ 548

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  592 AME-------ELKVSFNKGVGAQTAEFAELKTqmekVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKL---------- 654
Cdd:TIGR02168  549 AVVvenlnaaKKAIAFLKQNELGRVTFLPLDS----IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllgg 624

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  655 LEVTEEKEQTLENLKAKLES----VEDQHLV----------------------EMEDTLNKLQEAEIKVKELDV-LQAKC 707
Cdd:TIGR02168  625 VLVVDDLDNALELAKKLRPGyrivTLDGDLVrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKaLAELR 704

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  708 NEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKL 787
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  788 LDLEK-------NLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM 860
Cdd:TIGR02168  785 EELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  861 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK 940
Cdd:TIGR02168  865 EELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQER 944

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624  941 AEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL---------QAKYEKETSEMITKHDADIKGFKQNLLDA 1009
Cdd:TIGR02168  945 LSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 392-1255 2.33e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 82.81  E-value: 2.33e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  392 ELALVRDGHDRHVLEMEAKMDQLRAMveAADREKVELLNQLEEEKRKVED----LQFRVEEESITKGDLEVATVSEKsrI 467
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERL--RREREKAERYQALLKEKREYEGyellKEKEALERQKEAIERQLASLEEE--L 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  468 MELERDLALRVKEVAELRGRLESskhiddvdtslsLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKtlS 547
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEE------------LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE--D 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  548 ASNERMGKENESLKTKLDHANKENSdvIELWKSKLESAIASHQQAMEELKVSFNKgVGAQTAEFAELKtqmEKVKlDYEN 627
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELERE--IEEERKRRDKLTEEYAELKEELEDLRAE-LEEVDKEFAETR---DELK-DYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  628 EMSNLKLKQEneksqhlkEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemedtlNKLQEaeikvkELDVLQAKC 707
Cdd:TIGR02169  393 KLEKLKREIN--------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKI--------NELEE------EKEDKALEI 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  708 NEQTKLIGSLTQQIRASEEKLLDLAALQKANSEgklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQG----- 782
Cdd:TIGR02169  451 KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEK---ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtv 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  783 ------KEQKLLDLE----KNLSAVNQVKDSLEKE-LQLLKEKftsavdgaeNAQRAMQETINKLNQKEEQ--------- 842
Cdd:TIGR02169  528 aqlgsvGERYATAIEvaagNRLNNVVVEDDAVAKEaIELLKRR---------KAGRATFLPLNKMRDERRDlsilsedgv 598

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  843 --FALMSSELEQLKSNLTVM---ETKLKEREE--REQQLTEAKVKLENDIAE--------IMKSSGDSS------AQLMK 901
Cdd:TIGR02169  599 igFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEaaRRLMGKYRMVTLEGELFEksgamtggSRAPRGGILfsrsepAELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  902 MNDELRLKERQLEQIQLELTKAnekavqlqknveqtaqkaeqsqqetlkthQEELKKMQDQLTDMKKQMETSQNQYKDLQ 981
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRI-----------------------------ENRLDELSQELSDASRKIGEIEKEIEQLE 729

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  982 AKYEKEtSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE--QAKSLSSVLASARKEIELMSDKMR 1059
Cdd:TIGR02169  730 QEEEKL-KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSKLEEEVS 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1060 DLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALI 1139
Cdd:TIGR02169  809 RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK 888

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1140 SEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRV---IK 1216
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVeeeIR 968

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 2024359624 1217 DKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQE 1255
Cdd:TIGR02169  969 ALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1163-1956 1.55e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 1.55e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1163 NDALRSSESTLL-QQLKELQANKDAVDVACQKHIKEREELehyQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQ 1241
Cdd:TIGR02168  219 KAELRELELALLvLRLEELREELEELQEELKEAEEELEEL---TAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1242 EVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELE 1321
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1322 TEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL---VNENKAVTEKLTKA 1398
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1399 TADAVLAETAFTEKINELNLEKESVFSK--SLQFEKHN-EALLREKDELERKYSELLDEKKSLENAFS--------DMKR 1467
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERElaQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvDEGY 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1468 EQELDF----SAKRLLVQENTTLKYSIEALEEELKKK------------------NLENQELIACRSDLSDLLKEAQDAR 1525
Cdd:TIGR02168  536 EAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldsikgteiqgndREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1526 RTLENELAAVshakqVLSSSFNTCSSDIEILNRERT------ELQDKCQKLTGEVENmKENLTVEKKARILDKESfllER 1599
Cdd:TIGR02168  616 KALSYLLGGV-----LVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAK-TNSSILERRREIEELEE---KI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1600 MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAEL 1679
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1680 EDvhscvsvMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvVALLEQTDADFSC 1759
Cdd:TIGR02168  767 EE-------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER-LESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1760 RLLVSEGKHELLLEEMSNLALKLRE----IERLQAQT------FMQKFEADKRAEEVLQTMEKVTKEKDaihQEKIETLA 1829
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEEleelIEELESELeallneRASLEEALALLRSELEELSEELRELE---SKRSELRR 915

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1830 SLENSRQTNEKLQNELDMLKQNNLKNEEELTkSKELLNLENKKVEELKKEFEALKLAAAQKS--QQLAALQEENVKLAEE 1907
Cdd:TIGR02168  916 ELEELREKLAQLELRLEGLEVRIDNLQERLS-EEYSLTLEEAEALENKIEDDEEEARRRLKRleNKIKELGPVNLAAIEE 994

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359624 1908 LgrsrdevtshQKLEEERSVLNNQLLEMKKSLpsNTLRESTlkKEIDEE 1956
Cdd:TIGR02168  995 Y----------EELKERYDFLTAQKEDLTEAK--ETLEEAI--EEIDRE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 590-1435 1.94e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 1.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  590 QQAMEELKVsfnkgVGAQTAEF----AELKTQMEKVKLDYENEMSNLKL---KQENEKSQHLKEIEALKAKLLEVT---E 659
Cdd:TIGR02169  173 EKALEELEE-----VEENIERLdliiDEKRQQLERLRREREKAERYQALlkeKREYEGYELLKEKEALERQKEAIErqlA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  660 EKEQTLENLKAKLESVEDQhLVEMEDTLNKLqEAEIKVK---ELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 736
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKR-LEEIEQLLEEL-NKKIKDLgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  737 ansEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKft 816
Cdd:TIGR02169  326 ---KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE-- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  817 savdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 896
Cdd:TIGR02169  401 ------------INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  897 AQLMKMNDELRLKERQLEQIQLELTKAnekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ-- 974
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIev 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  975 ---------------------NQYKDLQA---------KYEKETSEMITKHDADIKGFKQNLLDAE-------------- 1010
Cdd:TIGR02169  544 aagnrlnnvvveddavakeaiELLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDpkyepafkyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1011 ---EALKAAQKKNDE--LETQAEELKKQ-------AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLE 1078
Cdd:TIGR02169  624 lvvEDIEAARRLMGKyrMVTLEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1079 KESLLSQHLEMESKILLVQQDREELwtkNEELNSENKKIlkqkEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLK 1158
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERL----EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1159 ITQENDALRSSESTllQQLKELQANKDAVDvacqkhikereelehyqklleendrvikdkdDVIQRLQSSYDDLARNQRE 1238
Cdd:TIGR02169  777 LEEALNDLEARLSH--SRIPEIQAELSKLE-------------------------------EEVSRIEARLREIEQKLNR 823

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1239 LLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQT 1318
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1319 ELETEREKLEKMTKDNMDLKASLSSLSNFLEEM-KSSREASNSEKIHLLQEALFASEQRLLAEREEL--VNeNKAVTE-K 1394
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIeDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepVN-MLAIQEyE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359624 1395 LTKATAD------AVLAE--TAFTEKINELNLEKESVFSKSlqFEKHNE 1435
Cdd:TIGR02169  983 EVLKRLDelkekrAKLEEerKAILERIEEYEKKKREVFMEA--FEAINE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 681-1627 2.15e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.15e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  681 VEMEDTLNKLQEAEIKVKELDVLQAKCNEQTkligsltQQIRASEEKLLDLAALQKanSEGKLEIQKLSEQLQAAEKQIQ 760
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQL-------ERLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  761 NLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQllkekftsavDGAENAQRAMQETINKLnqke 840
Cdd:TIGR02169  241 AIERQ-------LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK----------DLGEEEQLRVKEKIGEL---- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  841 eqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlkERQLEQIQLEL 920
Cdd:TIGR02169  300 ------EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL---------------------EREIEEERKRR 352

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  921 TKANEKAVQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIK 1000
Cdd:TIGR02169  353 DKLTEEYAELKEELEDLRAELEE-VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-LADLNAAIA 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1001 GFKQNLLDAEEalkaaqkkndELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKE 1080
Cdd:TIGR02169  431 GIEAKINELEE----------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1081 SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQE---STEKVAliSEKSKLLSEIETAQADLL 1157
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNvvvEDDAVA--KEAIELLKRRKAGRATFL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1158 KITQENDALRssestLLQQLKELQANKDAVD-VACQKHIKER-----------EELEHYQKLLEENDRV-----IKDKDD 1220
Cdd:TIGR02169  579 PLNKMRDERR-----DLSILSEDGVIGFAVDlVEFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKYRMVtlegeLFEKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1221 VIQRLQSSYDDLARNQRELLQEVSILTAERDSaqekdldlksthiaLKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLA 1300
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1301 NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAE 1380
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE--------EDLHKLEEALNDLEARLSHS 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1381 R-----------EELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYS 1449
Cdd:TIGR02169  792 RipeiqaelsklEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1450 ELLDEKKSLENAFSDMKREqeldfsakrllvqenttlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLE 1529
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKE---------------------RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1530 NELAAVSHAKQVLSSSfNTCSSDIEILNRERTELQDKCQKLtGEVeNMKEnltvekkarILDKESFLLERMELQNNIGFL 1609
Cdd:TIGR02169  931 EELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRAL-EPV-NMLA---------IQEYEEVLKRLDELKEKRAKL 998

                          970
                   ....*....|....*...
gi 2024359624 1610 EKEVEEMREKNKEFLTEK 1627
Cdd:TIGR02169  999 EEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 353-972 2.17e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.21  E-value: 2.17e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  353 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELE----AELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  433 EEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtslSLLQEISSLQE 512
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE------------EAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  513 KMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKensdvielwKSKLESAIASHQQA 592
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLER---------LERLEEELEELEEA 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  593 MEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKL 672
Cdd:COG1196    430 LAELEEE------EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  673 ESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL 752
Cdd:COG1196    504 EGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  753 QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQLLKEKFTSAVDGAENAQRA 828
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  829 MQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL 908
Cdd:COG1196    664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624  909 KERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQDQLTDMKKQMET 972
Cdd:COG1196    744 EEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLSEQREDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 346-1082 3.33e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.96  E-value: 3.33e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  346 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQeLALVRDghdrhVLEMEAKMDQLRAMVEA----- 420
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ-LRVKEK-----IGELEAEIASLERSIAEkerel 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  421 --ADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLES-SKHIDDV 497
Cdd:TIGR02169  318 edAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDyREKLEKL 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  498 DTSL-SLLQEISSLQE---KMAAAGKEHQREMSSLKEK---FESSEEALRKEIK-------TLSASNERMGKENESLKTK 563
Cdd:TIGR02169  398 KREInELKRELDRLQEelqRLSEELADLNAAIAGIEAKineLEEEKEDKALEIKkqewkleQLAADLSKYEQELYDLKEE 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  564 LDHANKENSDVielwKSKLESAIASHQQ---------AMEELKVSFNKGVGAQTAEFAELKTQMEK-VKLDYENEMSNLK 633
Cdd:TIGR02169  478 YDRVEKELSKL----QRELAEAEAQARAseervrggrAVEEVLKASIQGVHGTVAQLGSVGERYATaIEVAAGNRLNNVV 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  634 LKQEN---EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ--HLVEMEDtlnKLQEAEIKVKELDVLQAKCN 708
Cdd:TIGR02169  554 VEDDAvakEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFavDLVEFDP---KYEPAFKYVFGDTLVVEDIE 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  709 EQTKLIGSLTQQIRASE--EK-------LLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKE 779
Cdd:TIGR02169  631 AARRLMGKYRMVTLEGElfEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  780 LQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSnltv 859
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA---- 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  860 metklKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQLELTKANEKAVQ-----LQK 932
Cdd:TIGR02169  787 -----RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYleKEIQELQEQRIDLKEQIKSIEkeienLNG 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  933 NVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETsemitKHDADIKGFKQNLLDAEEA 1012
Cdd:TIGR02169  862 KKEELEEELEELEAA-LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR-----KRLSELKAKLEALEEELSE 935

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1013 LKAAQKKNDE-------LETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL 1082
Cdd:TIGR02169  936 IEDPKGEDEEipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 744-1350 1.44e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 76.60  E-value: 1.44e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  744 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAE 823
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  824 NAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 903
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  904 DEL---RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKdl 980
Cdd:TIGR04523  201 LLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTE-ISNTQTQLNQLKDEQNKIKKQLSEKQKELE-- 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  981 qakyekETSEMITKHDADIKGFKQNLLDAEEalkaaQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD 1060
Cdd:TIGR04523  278 ------QNNKKIKELEKQLNQLKSEISDLNN-----QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1061 LISEKETLAQERNTLKLEKEsllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS 1140
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1141 EKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDA----VDVACQKHIKEREELEHYQKLLEENDRVIK 1216
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESletqLKVLSRSINKIKQNLEQKQKELKSKEKELK 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1217 DKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS---------THIALKNEIDCLLQTNRSLQSEKEM 1287
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKNKEIEELKQTQKS 579

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624 1288 LLKSREELCVSLANTANENQALK---LRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEE 1350
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIkeiEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 357-1130 1.95e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.26  E-value: 1.95e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  357 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEE 434
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  435 EKRKVEdLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRvkEVAELRGRLESSKHIDDvdtslSLLQEISSLQEKM 514
Cdd:TIGR02169  295 KIGELE-AEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA--EIEELEREIEEERKRRD-----KLTEEYAELKEEL 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  515 AAAgkehQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKSKLESAIASHQQAME 594
Cdd:TIGR02169  367 EDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL-NAAIAGIEAKINELEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  595 ELKVSFNKgVGAQTAEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKL-------------LEVTEEK 661
Cdd:TIGR02169  442 EKEDKALE-IKKQEWKLEQLAADLSKYEQELYDLKEEYD-RVEKELSKLQRELAEAEAQAraseervrggravEEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  662 EQTLENLKAKLESVEDQHLVEMEDTL-NKLQEAeikVKELDVLQAKCNEQTKL--IGSLT-QQIRASEEKLLDLAALQKA 737
Cdd:TIGR02169  520 IQGVHGTVAQLGSVGERYATAIEVAAgNRLNNV---VVEDDAVAKEAIELLKRrkAGRATfLPLNKMRDERRDLSILSED 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  738 NSEG-KLEIQKLSEQLQAAEKQI-------QNLETEK----------------------VGGSSKVSN-------LTKEL 780
Cdd:TIGR02169  597 GVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARrlmgkyrmvtlegelfeksgamTGGSRAPRGgilfsrsEPAEL 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  781 QGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM 860
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  861 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDS-----SAQLMKMNDELRLKERQLEQIQLELtkaneKAVQLQKNVE 935
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSripeiQAELSKLEEEVSRIEARLREIEQKL-----NRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  936 QTAQKAEQSQQETLKTHQEELKKMQD----QLTDMKKQMETSQNQYKDLQAKYeketsemitkhdadiKGFKQNLLDAEE 1011
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRL---------------GDLKKERDELEA 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1012 ALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEK---ETLAQERNTLKLEKESLLSQHLE 1088
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNML 976

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 2024359624 1089 MESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQ 1130
Cdd:TIGR02169  977 AIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1314-2081 3.63e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 3.63e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1314 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLA-EREELVNENKAVT 1392
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--KAERYQALLKEKREYEGYELLkEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1393 EKLtkATADAVLAEtaFTEKINELNLEKESVFSKSLQFEKHNEALLR-EKDELERKYSELLDEKKSLENAFSDMKREQEL 1471
Cdd:TIGR02169  244 RQL--ASLEEELEK--LTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1472 DFSAKRLLVQENTTLKYSIEALEEELKKKNLEnqeliacRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1551
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKR-------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1552 DIEILNRERTE-------LQDKCQKLTGEVENMKENLTVeKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFL 1624
Cdd:TIGR02169  393 KLEKLKREINElkreldrLQEELQRLSEELADLNAAIAG-IEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1625 TEKELLVQEKEKSETKLEEVIKEkmILYKETEQLASKIEQLKSDFTSLsVSKAELEDVHSCVSvMLDELQHKY------- 1697
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRE--LAEAEAQARASEERVRGGRAVEE-VLKASIQGVHGTVA-QLGSVGERYataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1698 ------------EVTEKEKMELVQENESLHAEWKSLVIINEEiLKEKEKLSK-----------EYYKLHEKVVA------ 1748
Cdd:TIGR02169  545 agnrlnnvvvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEdgvigfavdlvEFDPKYEPAFKyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1749 -LLEQTDAD----FSCRLLVSEGKhelLLEE---MSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAI 1820
Cdd:TIGR02169  624 lVVEDIEAArrlmGKYRMVTLEGE---LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1821 HQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEE 1900
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1901 NVKLAEELGRSR-DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEI----------DEERASLQKSISDTS 1968
Cdd:TIGR02169  781 LNDLEARLSHSRiPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIqelqeqridlKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1969 ALITQKDEELEKLRNEITVLRGEnasAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDE 2048
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESR---LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2024359624 2049 SAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2081
Cdd:TIGR02169  938 DPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 470-1200 6.25e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 74.77  E-value: 6.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  470 LERDLALRVKEVAELRGRLESSKHIDDvDTSLSLLQEISSLQEKMAAAGKEHQrEMSSLKEKFESSEEALRKEIKTLSas 549
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNELHE-KQKFYLRQSVIDLQTKLQEMQMERD-AMADIRRRESQSQEDLRNQLQNTV-- 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  550 nermgKENESLKT-KLDHANKENSDVIELWKSKLesaiaSHQQAMEELK---VSFNKGVGAQ--------TAEFAELKTQ 617
Cdd:pfam15921  152 -----HELEAAKClKEDMLEDSNTQIEQLRKMML-----SHEGVLQEIRsilVDFEEASGKKiyehdsmsTMHFRSLGSA 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  618 MEKVKLDYENEMSNLKLKQENEKSQhlkeIEALKAkllEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKV 697
Cdd:pfam15921  222 ISKILRELDTEISYLKGRIFPVEDQ----LEALKS---ESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  698 K----ELDVLQAKCNEQTKLIGSLTQQIRASEEKLLdlAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKV 773
Cdd:pfam15921  295 NsiqsQLEIIQEQARNQNSMYMRQLSDLESTVSQLR--SELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQES 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  774 SNLTKELQG------KEQKLLDLEKN----------------------LSAVNQVKDSLEKELQLLKEKFTSAVDGAENA 825
Cdd:pfam15921  373 GNLDDQLQKlladlhKREKELSLEKEqnkrlwdrdtgnsitidhlrreLDDRNMEVQRLEALLKAMKSECQGQMERQMAA 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  826 QRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT----EAKVKLENDIAEIMKSSGDSSAQLMK 901
Cdd:pfam15921  453 IQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTaslqEKERAIEATNAEITKLRSRVDLKLQE 532

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  902 MN------DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMEtsqn 975
Cdd:pfam15921  533 LQhlknegDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-HGRTAGAMQVEKAQLEKEINDRRLELQ---- 607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  976 QYKDLQAKYEKETSEMITKHdADIKGFKQNLLDA-EEALKAA----QKKN---DELETQAEELKKQAEQAKSLSSVLASA 1047
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARV-SDLELEKVKLVNAgSERLRAVkdikQERDqllNEVKTSRNELNSLSEDYEVLKRNFRNK 686

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1048 RKEIELMSDKMR-DLISEKETLAQERNTLKlekesllSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEA 1126
Cdd:pfam15921  687 SEEMETTTNKLKmQLKSAQSELEQTRNTLK-------SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1127 KSRqestEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVA---CQKHIKEREE 1200
Cdd:pfam15921  760 ANK----EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQfaeCQDIIQRQEQ 832
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1098-2020 2.07e-12

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 73.16  E-value: 2.07e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1098 QDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1177
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1178 KELQANKDAVDVACQKHIKEREEleHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSI--LTAERDSAQE 1255
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYH--NHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqLQADRHQEHI 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1256 KDLDLKSTHIALKNEIDCLLQ---TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1332
Cdd:TIGR00606  364 RARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1333 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEK 1412
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQE 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1413 INELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDE------KKSLENAFSDMKREQ---ELDFSAKRLLVQEN 1483
Cdd:TIGR00606  524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEInqtRDRLAKLNKELASL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1484 TTLKYSIEALEEELKKKNLENQELI-------ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEIL 1556
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSSYEDKLfdvcgsqDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVC 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1557 NR------ERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELL 1630
Cdd:TIGR00606  684 QRvfqteaELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1631 VQEKEKSETKLEEVIKEkmilyketEQLAskiEQLKSDFTSLSVSKAELEDVhscvsvmldelqhkyevtEKEKMELVQE 1710
Cdd:TIGR00606  764 KNDIEEQETLLGTIMPE--------EESA---KVCLTDVTIMERFQMELKDV------------------ERKIAQQAAK 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1711 NESLhaewkSLVIINEEILKEKEKLSKEYYKLHEKVvALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQA 1790
Cdd:TIGR00606  815 LQGS-----DLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1791 QTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNnLKNEEELTKSKELLNLEN 1870
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK-VKNIHGYMKDIENKIQDG 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1871 KKVEELKKEFEALKLAAaqksqQLAALQEENVKLAEELGRSRDEVTSHQKLEeerSVLNNQLLEMKkslpsntlRESTLK 1950
Cdd:TIGR00606  968 KDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQE---RWLQDNLTLRK--------RENELK 1031

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1951 kEIDEERASLQKSISDTSalITQKDEELEKLRNEITVLRGENASAKTLQsvvKTLESDKLKLEEKVKNLE 2020
Cdd:TIGR00606 1032 -EVEEELKQHLKEMGQMQ--VLQMKQEHQKLEENIDLIKRNHVLALGRQ---KGYEKEIKHFKKELREPQ 1095
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 631-1232 4.02e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.59  E-value: 4.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  631 NLKLKQENEKSQHLKEIEALKAKLlevtEEKEQTLENL-KAKLESVEDQHLVEMEDTLNKLQEAEIKVKE------LDVL 703
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNEL----KNKEKELKNLdKNLNKDEEKINNSNNKIKILEQQIKDLNDKLkknkdkINKL 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  704 QAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKL-----------EIQKLSEQLQAAEKQIQNLETEKVGGSSK 772
Cdd:TIGR04523  102 NSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDkflteikkkekELEKLNNKYNDLKKQKEELENELNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  773 VSNLTKELQGKEQKLLDLEKNLS---AVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE 849
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLSnlkKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  850 LEQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK-MNDELRLKERQLEQIQLELTKANEKAV 928
Cdd:TIGR04523  262 QNKIKKQL---SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKeLKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  929 QLQKNVEQTAQKAEQSQQETLKThQEELKKMQDQLTDMKKQmetsQNQYKDLQAKYEKETSEMITKhdadIKGFKQNLLD 1008
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEK-QRELEEKQNEIEKLKKE----NQSYKQEIKNLESQINDLESK----IQNQEKLNQQ 409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1009 AEEALKAAQKKNDELETQAEELK----KQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLS 1084
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKetiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1085 QHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISE---------KSKLLSEIETAQAD 1155
Cdd:TIGR04523  490 ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDElnkddfelkKENLEKEIDEKNKE 569

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1156 LLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIkdkDDVIQRLQSSYDDL 1232
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKL---SSIIKNIKSKKNKL 643
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-960 4.22e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 72.07  E-value: 4.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  427 ELLNQLEEekrkvedlQFRVEEESITKGDLEVATVSEKSRIM--ELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLl 504
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERDQFSQESGNLddQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSI- 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  505 qEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENeSLKTKLDHANKENSDVIELWKSKlES 584
Cdd:pfam15921  413 -TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMLRKVVEELTAK-KM 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  585 AIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyenemsNLKLKQenekSQHLKEiealkakllevteeKEQT 664
Cdd:pfam15921  490 TLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---------DLKLQE----LQHLKN--------------EGDH 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  665 LENLKAKLESVedqhlvemedtlnKLQEAEiKVKELDVLQAKCNEQTKLIGsltQQIRASEEKLLDLAALQKANSEGKLE 744
Cdd:pfam15921  543 LRNVQTECEAL-------------KLQMAE-KDKVIEILRQQIENMTQLVG---QHGRTAGAMQVEKAQLEKEINDRRLE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  745 IQKLS-------EQLQAAEKQIQNLETEKV----GGSSKVSNLTKELQGKEQKLLDLEKNLSAVNqvkdSLEKELQLLKE 813
Cdd:pfam15921  606 LQEFKilkdkkdAKIRELEARVSDLELEKVklvnAGSERLRAVKDIKQERDQLLNEVKTSRNELN----SLSEDYEVLKR 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  814 KFTSAVDGAE-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTVMETKLKERE 868
Cdd:pfam15921  682 NFRNKSEEMEtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNAN 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  869 EREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQET 948
Cdd:pfam15921  762 KEKHFLKEEKNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837

                          650
                   ....*....|..
gi 2024359624  949 LKTHQEELKKMQ 960
Cdd:pfam15921  838 KLQHTLDVKELQ 849
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.70e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.70e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 471-1218 3.53e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 69.10  E-value: 3.53e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  471 ERDLALRVKEVAElrgrlESSKHIDDVDTSLSLLQEISSLQEKMaaagKEHQREMSSLKEKFESSEEALRKEIKTLSAS- 549
Cdd:pfam12128  229 DIQAIAGIMKIRP-----EFTKLQQEFNTLESAELRLSHLHFGY----KSDETLIASRQEERQETSAELNQLLRTLDDQw 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  550 NERMGKENESLKT-KLDHANKENS-DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYEN 627
Cdd:pfam12128  300 KEKRDELNGELSAaDAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNR 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  628 EMSNLKlkqenekSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVK----ELDVL 703
Cdd:pfam12128  380 RRSKIK-------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKsrlgELKLR 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  704 QAkcneqtkligsltqQIRASEEKLLDLAALQKansegklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGK 783
Cdd:pfam12128  453 LN--------------QATATPELLLQLENFDE-------RIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQA 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  784 EQKLLDLEKNLSAVNQVKDS--------LEKELQLLKEKFTSAVDGA-----------ENAQRAMQETINKLNQKEEQFA 844
Cdd:pfam12128  512 SRRLEERQSALDELELQLFPqagtllhfLRKEAPDWEQSIGKVISPEllhrtdldpevWDGSVGGELNLYGVKLDLKRID 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  845 LMSSEL--EQLKSNLTVMETKLKEREEREQQLTEAKVKLendiaeimkssgdsSAQLMKMNDELRLKERQLEQIQLELTK 922
Cdd:pfam12128  592 VPEWAAseEELRERLDKAEEALQSAREKQAAAEEQLVQA--------------NGELEKASREETFARTALKNARLDLRR 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  923 ANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMetsQNQYKDLQAKYEKETSEMITKHDADIKGF 1002
Cdd:pfam12128  658 LFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREARTEKQAYWQVVEGALDAQLALL 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1003 KQNLLDAEEALKAAQKkndELETQ-AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKES 1081
Cdd:pfam12128  735 KAAIAARRSGAKAELK---ALETWyKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPR 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1082 LLSQHLEMESKILLVQQDreeLWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSeietaqadlLKITQ 1161
Cdd:pfam12128  812 LATQLSNIERAISELQQQ---LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT---------LKEDA 879

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1162 ENDALRSSESTLLQQLKELQANKDAVDVACQKHI---------KEREEL-EHYQKlLEENDRVIKDK 1218
Cdd:pfam12128  880 NSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVehfknviadHSGSGLaETWES-LREEDHYQNDK 945
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 422-1261 3.57e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 68.84  E-value: 3.57e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  422 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSL 501
Cdd:pfam02463  168 KRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  502 SLLQEISSLQEKMAAAGKEHQREMSSLKEkfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSK 581
Cdd:pfam02463  248 DEQEEIESSKQEIEKEEEKLAQVLKENKE--EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  582 LESAIASHQQAMEELKVSfNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQEnEKSQHLKEIEALKAKLLEVTEEK 661
Cdd:pfam02463  326 AEKELKKEKEEIEELEKE-LKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK-LESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  662 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEiKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEG 741
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEE-ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  742 KLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDG 821
Cdd:pfam02463  483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  822 AENAQRAMQETINKLNQKEE--QFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD----- 894
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLkesak 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  895 ---SSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQS--QQETLKTHQEELKKMQDQLTDMKKQ 969
Cdd:pfam02463  643 akeSGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILrrQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  970 METSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARK 1049
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1050 EIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELN---SENKKILKQKEAAEA 1126
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITkeeLLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1127 KSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQK 1206
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERN 962

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1207 LLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvsILTAERDSAQEKDLDLK 1261
Cdd:pfam02463  963 KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE--RLEEEKKKLIRAIIEET 1015
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 619-1161 4.10e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.51  E-value: 4.10e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  619 EKVKLDYENEmsnlKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKlesveDQHLVEMEDTLNKLQEAEIKVK 698
Cdd:TIGR04523  165 KKQKEELENE----LNLLEKEKLNIQKNIDKIKNKLLK----LELLLSNLKKK-----IQKNKSLESQISELKKQNNQLK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  699 E-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLD----LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKv 773
Cdd:TIGR04523  232 DnIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  774 sNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQL 853
Cdd:TIGR04523  311 -ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  854 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 933
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  934 VEQTAQKAEQSQQeTLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEAL 1013
Cdd:TIGR04523  470 LKVLSRSINKIKQ-NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK-ISSLKEKIEKLESEKKEKESKISDLEDEL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1014 KA--AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmrDLISEKETlaqerntlklEKESLLSQHLEMES 1091
Cdd:TIGR04523  548 NKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ-------ELIDQKEK----------EKKDLIKEIEEKEK 610

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1092 KILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1161
Cdd:TIGR04523  611 KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 406-1397 6.23e-11

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 68.28  E-value: 6.23e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALrvkeVAELR 485
Cdd:pfam01576   72 ELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILL----LEDQN 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  486 GRLESSKhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESS----EEALRKEiktlsasnERMGKENESLK 561
Cdd:pfam01576  148 SKLSKER---------KLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMisdlEERLKKE--------EKGRQELEKAK 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  562 TKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFA------ELKTQMEKVKLDYENEMSnLKLK 635
Cdd:pfam01576  211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkkirELEAQISELQEDLESERA-ARNK 289

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  636 QENEKSQHLKEIEALKAKLL----------EVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAeikvkeLDVLQA 705
Cdd:pfam01576  290 AEKQRRDLGEELEALKTELEdtldttaaqqELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA------LEELTE 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  706 KCNEQTKLIGSLTQQIRASEEKLLDLAA----LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQ 781
Cdd:pfam01576  364 QLEQAKRNKANLEKAKQALESENAELQAelrtLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELE 443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  782 GKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTsavdgaenaqramQETINKLNqkeeqfalMSSELEQLKSNLTVME 861
Cdd:pfam01576  444 SVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQ-------------EETRQKLN--------LSTRLRQLEDERNSLQ 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  862 TKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKA 941
Cdd:pfam01576  503 EQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQEL 582

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  942 EQS--QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDAdikgFKQNLLDAEEALKAAQKK 1019
Cdd:pfam01576  583 DDLlvDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS----LARALEEALEAKEELERT 658

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1020 NDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEkesllsqhLEMESKILLVQQD 1099
Cdd:pfam01576  659 NKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLR--------LEVNMQALKAQFE 730

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1100 ReELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLlkitqenDALRSSESTLLQQLKE 1179
Cdd:pfam01576  731 R-DLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQI-------DAANKGREEAVKQLKK 802

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1180 LQANKDAVDVACQKHIKEREELEHYQKlleENDRVIKDKDDVIQRLQssyDDLARNQRELLQevsiLTAERDSAQEKDLD 1259
Cdd:pfam01576  803 LQAQMKDLQRELEEARASRDEILAQSK---ESEKKLKNLEAELLQLQ---EDLAASERARRQ----AQQERDELADEIAS 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1260 LKSTHIALKNEidcllqtNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKA 1339
Cdd:pfam01576  873 GASGKSALQDE-------KRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLER 945

                          970       980       990      1000      1010
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624 1340 SLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTK 1397
Cdd:pfam01576  946 QNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKK 1003
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1309-1987 6.91e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.84  E-value: 6.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1385
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1386 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1460
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1461 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1538
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1539 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1599
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1600 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1670
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1671 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1747
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1748 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1823
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1824 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1891
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1892 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1952
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359624 1953 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1987
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1729-2028 7.97e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.97e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1729 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1808
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1809 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1888
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1889 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1968
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1969 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2028
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1164 8.58e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.86  E-value: 8.58e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  335 GLLTETSSRYARKISGTTALQEALK--EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDGHDRHVLEMEAKMD 412
Cdd:PTZ00121  1098 GKAEEAKKTETGKAEEARKAEEAKKkaEDARKAEEARKAEDARKAEEARK----AEDAKRVEIARKAEDARKAEEARKAE 1173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  413 QLRAMVEAADREKVELLNQLE--EEKRKVEDLQFRVEEESITkgdlEVATVSEKSRIMElerdlalrVKEVAELRGRLES 490
Cdd:PTZ00121  1174 DAKKAEAARKAEEVRKAEELRkaEDARKAEAARKAEEERKAE----EARKAEDAKKAEA--------VKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  491 SKHIDDVDTSlsllQEISSLQEKMAAagkEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKEneslKTKLDHANKE 570
Cdd:PTZ00121  1242 AKKAEEERNN----EEIRKFEEARMA---HFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE----KKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  571 nsdvielwksklesaiASHQQAMEELKvsfnkgvgaQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEAL 650
Cdd:PTZ00121  1311 ----------------AEEAKKADEAK---------KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK 1365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  651 KAKLLEVTEEKEQTLENLKAKLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLD 730
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKAEEKK-----KADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKA 1440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  731 LAALQKANSEGKLEIQKLSEQL--QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKEl 808
Cdd:PTZ00121  1441 EEAKKADEAKKKAEEAKKAEEAkkKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAE- 1519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  809 qllKEKFTSAVDGAENAQRAmqETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQL---TEAKVKLENDI 885
Cdd:PTZ00121  1520 ---EAKKADEAKKAEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALrkaEEAKKAEEARI 1594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  886 AEIMKSSGDSS---AQLMKMNDELRLKERQL----------EQIQLELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLK 950
Cdd:PTZ00121  1595 EEVMKLYEEEKkmkAEEAKKAEEAKIKAEELkkaeeekkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEeaKKAEEDK 1674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  951 THQEELKKMQDQLTDMKKQMETSQNQYKDLQaKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQ---KKNDELETQA 1027
Cdd:PTZ00121  1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEedkKKAEEAKKDE 1753

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1028 EELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEME-------SKILLVQQDR 1100
Cdd:PTZ00121  1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEgnlvindSKEMEDSAIK 1833

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1101 EELWTKNEELNsENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETA-QADLLKITQEND 1164
Cdd:PTZ00121  1834 EVADSKNMQLE-EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIeEADEIEKIDKDD 1897
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 931-1508 9.59e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.35  E-value: 9.59e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  931 QKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQaKYEKETSEMITKHDADIKGFKQNLLDAE 1010
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE-QQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1011 EALKAAQKKNDELETQAEELKKQAEQAKSL----SSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQH 1086
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNidkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1087 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEaaeaKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDAL 1166
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKK----QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1167 RSSESTLLQQLKELQANKDAVDVACQKHIKEREEL--EHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVS 1244
Cdd:TIGR04523  266 KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1245 ILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETER 1324
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1325 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfaseqrlLAEREELVNENKAVTEKLTKATADAVL 1404
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ---------LKVLSRSINKIKQNLEQKQKELKSKEK 496

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1405 AETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRL--LVQE 1482
Cdd:TIGR04523  497 ELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIeeLKQT 576

                          570       580
                   ....*....|....*....|....*.
gi 2024359624 1483 NTTLKYSIEALEEELKKKNLENQELI 1508
Cdd:TIGR04523  577 QKSLKKKQEEKQELIDQKEKEKKDLI 602
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
709-1225 9.84e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 9.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  709 EQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLL 788
Cdd:PRK03918   197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKDSLEK--ELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE 866
Cdd:PRK03918   277 ELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  867 REEREQQLTEAKVKLENdIAEIMKSSGDSSAQlmKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ- 945
Cdd:PRK03918   357 LEERHELYEEAKAKKEE-LERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKk 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  946 ---------QETLKTHQEEL-KKMQDQLTDMKKQMETSQNQYKDLQAkyEKETSEMITKHDADIKGFKQNLLDAEEALKA 1015
Cdd:PRK03918   434 akgkcpvcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRK--ELRELEKVLKKESELIKLKELAEQLKELEEK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 AQKKN-DELETQAEELKKQAEQAKSLS---SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL-LSQHLEME 1090
Cdd:PRK03918   512 LKKYNlEELEKKAEEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgFESVEELE 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1091 SKIllvqQDREELWTKNEELnSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEND------ 1164
Cdd:PRK03918   592 ERL----KELEPFYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeelre 666

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624 1165 ---ALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRL 1225
Cdd:PRK03918   667 eylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 785-1001 1.37e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.56  E-value: 1.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  785 QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKL 864
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  865 KEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN--------------DELRLKERQLEQIQLELTKANEKAVQL 930
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparreqaEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624  931 QKNVEQ---TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKG 1001
Cdd:COG4942    180 LAELEEeraALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
PTZ00121 PTZ00121
MAEBL; Provisional
 370-998 1.71e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.70  E-value: 1.71e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  370 AERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEE 449
Cdd:PTZ00121  1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED 1403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  450 SitKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKmaaagKEHQREMSSLK 529
Cdd:PTZ00121  1404 K--KKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK-----AEEAKKADEAK 1476

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  530 EKFESSEEAlrkeiktlsasnERMGKENESLKTKLDHANKENsdviELWKSKLESAIASHQQAMEELKvsfnKGVGAQTA 609
Cdd:PTZ00121  1477 KKAEEAKKA------------DEAKKKAEEAKKKADEAKKAA----EAKKKADEAKKAEEAKKADEAK----KAEEAKKA 1536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  610 EfaELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNK 689
Cdd:PTZ00121  1537 D--EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  690 LQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEklldlaaLQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGG 769
Cdd:PTZ00121  1615 AEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE-------LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  770 SSKVSNLTKELQGKeQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE 849
Cdd:PTZ00121  1688 KKAAEALKKEAEEA-KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  850 ----LEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANE 925
Cdd:PTZ00121  1767 ekkaEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEA 1846

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  926 KAVQLQK------NVEQTAQKAEQSQQETLKTHQEE---LKKMQDQL--TDMKKQMETSQNQYKDLQAKYEKETSEMITK 994
Cdd:PTZ00121  1847 DAFEKHKfnknneNGEDGNKEADFNKEKDLKEDDEEeieEADEIEKIdkDDIEREIPNNNMAGKNNDIIDDKLDKDEYIK 1926


                   ....
gi 2024359624  995 HDAD 998
Cdd:PTZ00121  1927 RDAE 1930
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 812-1629 2.11e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 66.30  E-value: 2.11e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  812 KEKFTSAVDGAENAQRAMQETINKLNQ-KEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQltEAKVKLEND 884
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQMErdamadIRRRESQSQE--DLRNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  885 IAEI----------MKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ-QETLKTHQ 953
Cdd:pfam15921  151 VHELeaakclkedmLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAiSKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  954 EELKKMQDQLTDMKKQMET----SQNQYKDLQAKYEKETSEMITKHDADIKGFKqnlldaeEALKAAQKKNDELETQAEE 1029
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLT-------EKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1030 LKKQAEQAKSLSsvlasarkeielmsdkMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1109
Cdd:pfam15921  304 IQEQARNQNSMY----------------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1110 LNSENKKILKQKEAAEAKSRQESTEkVALISEKSKLLSEIETAQADLLkitqenDALRSSESTLLQQLKELQANKDAVDV 1189
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKE-LSLEKEQNKRLWDRDTGNSITI------DHLRRELDDRNMEVQRLEALLKAMKS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1190 ACQKHIKER--------EELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQREllqeVSILTAerdSAQEKDLDLK 1261
Cdd:pfam15921  441 ECQGQMERQmaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT----VSDLTA---SLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1262 STH---IALKNEIDCLLQTNRSLQSEKEmllksreelcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKdnmdlk 1338
Cdd:pfam15921  514 ATNaeiTKLRSRVDLKLQELQHLKNEGD-----------HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ------ 576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1339 aslsslsnFLEEMKSSREASNSEKIHLLQEalfASEQRLlaEREELvnenkavteKLTKATADAVLAEtaFTEKINELNL 1418
Cdd:pfam15921  577 --------LVGQHGRTAGAMQVEKAQLEKE---INDRRL--ELQEF---------KILKDKKDAKIRE--LEARVSDLEL 632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1419 EKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-----EQELDFSAKRL----------LVQEN 1483
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnkSEEMETTTNKLkmqlksaqseLEQTR 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1484 TTLKySIEALEEELKKKNLENQELIACRSDLSDLLkeaQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTEL 1563
Cdd:pfam15921  713 NTLK-SMEGSDGHAMKVAMGMQKQITAKRGQIDAL---QSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624 1564 QDKCQKLTGEVENMKENLTVEKKAriLDKESflLERMELQNNIGflEKEVEEMREKNKEFLTEKEL 1629
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVA--LDKAS--LQFAECQDIIQ--RQEQESVRLKLQHTLDVKEL 848
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 336-1208 2.66e-10

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 65.97  E-value: 2.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  336 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERA-------EVAKATSHVGEIEQELALVRDGHDRHVLEME 408
Cdd:pfam01576   76 ILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAarqklqlEKVTTEAKIKKLEEDILLLEDQNSKLSKERK 155

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  409 AKMDQLRAMVE--AADREKVELLNQLEEEKRKV-EDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELR 485
Cdd:pfam01576  156 LLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  486 GRLesSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTlsasNERMGKENESLKTKLD 565
Cdd:pfam01576  236 AQL--AKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQ----RRDLGEELEALKTELE 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  566 HANKENSDVIELwKSKLESAIASHQQAMEELKVSFNKGVG----AQTAEFAELKTQMEKVKldyENEMSNLKLKQ--ENE 639
Cdd:pfam01576  310 DTLDTTAAQQEL-RSKREQEVTELKKALEEETRSHEAQLQemrqKHTQALEELTEQLEQAK---RNKANLEKAKQalESE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  640 KSQHLKEIEALKAKLLEVTEEK---EQTLENLKAKLESVEDQHlVEMEDTLNKLQ-EAEIKVKELDVLQAKCNEQTKLIG 715
Cdd:pfam01576  386 NAELQAELRTLQQAKQDSEHKRkklEGQLQELQARLSESERQR-AELAEKLSKLQsELESVSSLLNEAEGKNIKLSKDVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  716 SLTQQIRASEEKLldlaalqkansegkleiQKLSEQLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLS 795
Cdd:pfam01576  465 SLESQLQDTQELL-----------------QEETRQKLNLSTRLRQLEDER-------NSLQEQLEEEEEAKRNVERQLS 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  796 AVNQVKDSLEKELqllkEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT 875
Cdd:pfam01576  521 TLQAQLSDMKKKL----EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLV 596

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  876 EAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTaQKAEQSQQETLKTHQEE 955
Cdd:pfam01576  597 SNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERT-NKQLRAEMEDLVSSKDD 675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  956 LKK-----------MQDQLTDMKKQMETSQNQYK---DLQAKYEKETSEMITKHDADIKGFKQNlldAEEALKAAQKKND 1021
Cdd:pfam01576  676 VGKnvhelerskraLEQQVEEMKTQLEELEDELQateDAKLRLEVNMQALKAQFERDLQARDEQ---GEEKRRQLVKQVR 752

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1022 ELETQAEELKKQAEQA-----------KSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEME 1090
Cdd:pfam01576  753 ELEAELEDERKQRAQAvaakkkleldlKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESE 832

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1091 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSE 1170
Cdd:pfam01576  833 KKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRL 912

                          890       900       910
                   ....*....|....*....|....*....|....*...
gi 2024359624 1171 STLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLL 1208
Cdd:pfam01576  913 RKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKEL 950
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1196-2024 2.84e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 2.84e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1196 KEREELEHYQKLLEENDRVIKDKDDVIQRLQSsyddlarnqrellqevsiltaERDSAqEKDLDLKSTHIalKNEIDCLL 1275
Cdd:TIGR02169  174 KALEELEEVEENIERLDLIIDEKRQQLERLRR---------------------EREKA-ERYQALLKEKR--EYEGYELL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1276 QTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM-DLKASLSSLSNFLEEMKSS 1354
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1355 REASNSEKIHLLQEA--LFASEQRLLAEREEL---VNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQ 1429
Cdd:TIGR02169  310 IAEKERELEDAEERLakLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1430 FEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK----KKNLENQ 1505
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEqlaaDLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1506 ELIACRSDLSDLLKEAQDARRtlenELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLtGEVE---------- 1575
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQR----ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL-GSVGeryataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1576 --NMKENLTVEK-----------KARILDKESFL-----------LERMELQNNIGFLEKEVEEMREKNKEFL------- 1624
Cdd:TIGR02169  545 agNRLNNVVVEDdavakeaiellKRRKAGRATFLplnkmrderrdLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtl 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1625 ------TEKELLVQ-----------EKEKSET----KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvh 1683
Cdd:TIGR02169  625 vvedieAARRLMGKyrmvtlegelfEKSGAMTggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-- 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1684 scvsvMLDELQHKYEVTEKEKMELVQENESLHAEwkslviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLlv 1763
Cdd:TIGR02169  703 -----RLDELSQELSDASRKIGEIEKEIEQLEQE--------EEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-- 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1764 segkhELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA-EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQ 1842
Cdd:TIGR02169  768 -----EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1843 NELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLE 1922
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENL----------NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI---EELE 909

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1923 EERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEEraslqKSISDTSALITQKDEELEKLRNEITVLRGENASA------- 1995
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGED-----EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeev 984

                          890       900       910
                   ....*....|....*....|....*....|...
gi 2024359624 1996 ----KTLQSVVKTLESDKLKLEEKVKNLEQKLK 2024
Cdd:TIGR02169  985 lkrlDELKEKRAKLEEERKAILERIEEYEKKKR 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1610-2024 3.09e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.86  E-value: 3.09e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1610 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1689
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1690 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1769
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1770 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1849
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1850 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1924
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1925 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2004
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359624 2005 LESDKLKLEEKVKNLEQKLK 2024
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.09e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.09e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1773-2027 4.35e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 4.35e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1773 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1852
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1853 LKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK-----------L 1921
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeierlearlerL 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1922 EEERSVLNNQLLEMKKSLPSNTLRE-STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQS 2000
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          250       260
                   ....*....|....*....|....*..
gi 2024359624 2001 VVKTLESDKLKLEEKVKNLEQKLKAKS 2027
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLS 519
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 408-1093 7.54e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.37  E-value: 7.54e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  408 EAKMDQLRAMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESITKGDLE------VATVSEKSRIMELERDLALRVKE- 480
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESNELHEKQKfylrqsVIDLQTKLQEMQMERDAMADIRRr 135

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  481 ----VAELRGRLESSKHIDDVDTSLS--LLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEI----------- 543
Cdd:pfam15921  136 esqsQEDLRNQLQNTVHELEAAKCLKedMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIyehdsmstmhf 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  544 KTLSASNERMGKENESLKTKLDHANKENSDVIELWKS----KLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQME 619
Cdd:pfam15921  216 RSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSesqnKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQAN 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  620 KVkldyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDtlnkLQEAEIKVKE 699
Cdd:pfam15921  296 SI----QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSE----LTEARTERDQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  700 LDVLQAKCNEQ-TKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLE----TEKVGGSSKVS 774
Cdd:pfam15921  368 FSQESGNLDDQlQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEallkAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  775 NLTKELQGKEQKLldleKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLK 854
Cdd:pfam15921  448 RQMAAIQGKNESL----EKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  855 SNLTVMETKLKEREEREQQLTEAKVKLE---------NDIAEIMKSSGDSSAQLM---------------KMNDELRLKE 910
Cdd:pfam15921  524 SRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEILRQQIENMTQLVgqhgrtagamqvekaQLEKEINDRR 603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  911 RQLEQIQLELTKANEKAVQLQKNV---EQTAQKAEQSQQETLKThQEELKKMQDQLTDmkkQMETSQNQYKDLQAKYE-- 985
Cdd:pfam15921  604 LELQEFKILKDKKDAKIRELEARVsdlELEKVKLVNAGSERLRA-VKDIKQERDQLLN---EVKTSRNELNSLSEDYEvl 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  986 -------KETSEMIT-KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQ---------AEQAKS--LSSVLAS 1046
Cdd:pfam15921  680 krnfrnkSEEMETTTnKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQitakrgqidALQSKIqfLEEAMTN 759

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359624 1047 ARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKI 1093
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKV 806
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
620-1149 8.04e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 8.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  620 KVKLDYENEMSNLK--LKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKV 697
Cdd:PRK03918   169 EVIKEIKRRIERLEkfIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKE-VKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  698 ----KELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQ-----------------KANSEGKLEIQKLSEQLQAAE 756
Cdd:PRK03918   248 esleGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyiklsefyeeylDELREIEKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  757 KQIQNLETEKvggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKdSLEKELQLLKEKFT--------SAVDGAENAQRA 828
Cdd:PRK03918   328 ERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTgltpekleKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  829 MQETINKLNQKEEQFALMSSEL----EQLKS--------------------------NLTVMETKLKEREEREQQLTEAK 878
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELkkaiEELKKakgkcpvcgrelteehrkelleeytaELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  879 VKLENDIAEIMKSSgdssaQLMKMNDELRLKERQLEQIQLELTKANEKavqLQKNVEQTAQKAEqSQQETLKTHQEELKK 958
Cdd:PRK03918   483 RELEKVLKKESELI-----KLKELAEQLKELEEKLKKYNLEELEKKAE---EYEKLKEKLIKLK-GEIKSLKKELEKLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  959 MQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIK---GFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE 1035
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKelePFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1036 QAKSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEEL 1110
Cdd:PRK03918   634 ELAETEKRLEELRKELEELEkkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 2024359624 1111 NSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEI 1149
Cdd:PRK03918   714 EKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1173-1666 8.44e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 8.44e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1173 LLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDS 1252
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1253 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1332
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1333 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE---------ALFASEQRLLAEREELVNENKAVTEKLTKATADAV 1403
Cdd:COG1196    394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEAlaeleeeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1404 LAETAFTEKINELNlEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQEN 1483
Cdd:COG1196    474 LLEAALAELLEELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1484 TTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAkQVLSSSFNTCSSDIEILNRERTEL 1563
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD-LREADARYYVLGDTLLGRTLVAAR 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1564 QDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEE 1643
Cdd:COG1196    632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                          490       500
                   ....*....|....*....|...
gi 2024359624 1644 VIKEKMILYKETEQLASKIEQLK 1666
Cdd:COG1196    712 AEEERLEEELEEEALEEQLEAER 734
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1279-1865 8.98e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.31  E-value: 8.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1279 RSLQSEKEMLLKSREELCVSLANTANenqaLKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREAS 1358
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1359 NSEKIHLLQ-EALFASEQRLLAEREELVNENKAVTEKLT---------KATADAVLAETAFTEKINELNLEKESVFSKSL 1428
Cdd:PRK03918   241 EELEKELESlEGSKRKLEEKIRELEERIEELKKEIEELEekvkelkelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1429 QFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENttlKYSIEALEEELKKKNLENQELI 1508
Cdd:PRK03918   321 EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE---RLKKRLTGLTPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1509 ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSsdieILNRERTELQDK--CQKLTGEVENMKENL-TVEK 1585
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCP----VCGRELTEEHRKelLEEYTAELKRIEKELkEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1586 KARILDKESFLLER-MELQNNIGFLEKEVEEMREKNKEFlteKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQ 1664
Cdd:PRK03918   474 KERKLRKELRELEKvLKKESELIKLKELAEQLKELEEKL---KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1665 LKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLhE 1744
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-D 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1745 KVVALLEQTDADF-SCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhQE 1823
Cdd:PRK03918   630 KAFEELAETEKRLeELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER-EK 708

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2024359624 1824 KIETLASLENSRQTNEKLQNELDMLKqnNLKNEEELTKSKEL 1865
Cdd:PRK03918   709 AKKELEKLEKALERVEELREKVKKYK--ALLKERALSKVGEI 748
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 631-1470 9.68e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.22  E-value: 9.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  631 NLKLKQENE-KSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLEsvedqhLVEMEDTLNKLQEAEIKVKELDVLQAKCNE 709
Cdd:pfam02463  175 LKKLIEETEnLAELIIDLEELKLQELKLKEQAKKALEYYQLKEK------LELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  710 QTKLIGSLTQQIRASEEKLldlAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLD 789
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKL---AQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  790 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 869
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  870 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKavqlqknveqTAQKAEQSQQETL 949
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLK----------DELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  950 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEE 1029
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1030 LKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1109
Cdd:pfam02463  556 TADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELT 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1110 LNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDV 1189
Cdd:pfam02463  636 KLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKL 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1190 ACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLK--STHIAL 1267
Cdd:pfam02463  716 KLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKveEEKEEK 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1268 KNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNF 1347
Cdd:pfam02463  796 LKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLK 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1348 LEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS 1427
Cdd:pfam02463  876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 2024359624 1428 LQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQE 1470
Cdd:pfam02463  956 EEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
502-1078 2.11e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 2.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  502 SLLQEISSLQEKMAAAGKEHQrEMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIEL---- 577
Cdd:PRK03918   211 EISSELPELREELEKLEKEVK-ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkelk 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  578 WKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyeNEMSNLKLKQENEKSQHLKEIEALK--AKLL 655
Cdd:PRK03918   290 EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEerHELY 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  656 EVTEEKEQTLENLKAKLESVEdqhlveMEDTLNKLQEAEIKVKELdvlQAKCNEQTKLIGSLTQQIrasEEKLLDLAALQ 735
Cdd:PRK03918   365 EEAKAKKEELERLKKRLTGLT------PEKLEKELEELEKAKEEI---EEEISKITARIGELKKEI---KELKKAIEELK 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  736 KANSEGKLEIQKLSEQlqaAEKQIQNLETEKVggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVkdsLEKELQLLKEKf 815
Cdd:PRK03918   433 KAKGKCPVCGRELTEE---HRKELLEEYTAEL------KRIEKELKEIEEKERKLRKELRELEKV---LKKESELIKLK- 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  816 tSAVDGAENAQRAMQE-TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD 894
Cdd:PRK03918   500 -ELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKE 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  895 SSAQLMKMNDELRLKERQLEQIQLELTKAnekavqlqknveQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 974
Cdd:PRK03918   579 LEELGFESVEELEERLKELEPFYNEYLEL------------KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  975 NQYKDLQAKYEKETSEMItkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELM 1054
Cdd:PRK03918   647 KELEELEKKYSEEEYEEL----------REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKL 716

                          570       580
                   ....*....|....*....|....
gi 2024359624 1055 SDKMRDLISEKETLAQERNTLKLE 1078
Cdd:PRK03918   717 EKALERVEELREKVKKYKALLKER 740
PLN02939 PLN02939
transferase, transferring glycosyl groups
 641-971 2.47e-09

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 62.61  E-value: 2.47e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  641 SQHLKEIEALKAKLLEVTEEKEQ----TLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQakcneqtkligs 716
Cdd:PLN02939   102 MQRDEAIAAIDNEQQTNSKDGEQlsdfQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQ------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  717 ltQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLqaaEKQIQNLETEKVGGSSKVSNLTKELQgkeqkLLDLEkNLSa 796
Cdd:PLN02939   170 --GKINILEMRLSETDARIKLAAQEKIHVEILEEQL---EKLRNELLIRGATEGLCVHSLSKELD-----VLKEE-NML- 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  797 vnqvkdsLEKELQLLKEKFTSavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTE 876
Cdd:PLN02939   238 -------LKDDIQFLKAELIE-----------VAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWW 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  877 AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQiqlELTKAN------EKAVQLQKNVEQTAQKAEQSQQET-- 948
Cdd:PLN02939   300 EKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEA---SLKEANvskfssYKVELLQQKLKLLEERLQASDHEIhs 376

                          330       340
                   ....*....|....*....|....
gi 2024359624  949 -LKTHQEELKKMQDQLTDMKKQME 971
Cdd:PLN02939   377 yIQLYQESIKEFQDTLSKLKEESK 400
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 496-1218 2.99e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.43  E-value: 2.99e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  496 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI 575
Cdd:pfam05483   69 DFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLI 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  576 E------LWKSKLESAIAS----------HQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENE 639
Cdd:pfam05483  148 KennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEM-----HFKLKEDHE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  640 KSQHLKEiealkaKLLEVTEEKEQTLENLKAKLESVEDQhlveMEDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQ 719
Cdd:pfam05483  223 KIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----MKDLTFLLEESRDKANQLE-------EKTKLQDENLK 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  720 QIRASEEKLLDLAALQKANSEGKLEIQK-LSEQLQAAEKQIQNLETEKvggSSKVSNLTKELQGKEQKLLDLEKNLSAVN 798
Cdd:pfam05483  286 ELIEKKDHLTKELEDIKMSLQRSMSTQKaLEEDLQIATKTICQLTEEK---EAQMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  799 QVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAK 878
Cdd:pfam05483  363 ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKE-------VELEELKKILAEDEKLLDEKKQFEKIAEELK 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  879 VKLENDIAEIM---KSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQET------L 949
Cdd:pfam05483  436 GKEQELIFLLQareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAsdmtleL 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  950 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHD---ADIKGFKQNLLDAEEALKAAQKKNDELETQ 1026
Cdd:pfam05483  516 KKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDevkCKLDKSEENARSIEYEVLKKEKQMKILENK 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1027 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETlaqERNTLKLEKESLLSQHLEM----ESKILLVQQDREE 1102
Cdd:pfam05483  596 CNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEI---KVNKLELELASAKQKFEEIidnyQKEIEDKKISEEK 672

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1103 LWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS----EKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLK 1178
Cdd:pfam05483  673 LLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEkhkhQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIK 752

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2024359624 1179 -ELQANKDAVDVacqkhikEREELEHYQKLLEENDRVIKDK 1218
Cdd:pfam05483  753 aELLSLKKQLEI-------EKEEKEKLKMEAKENTAILKDK 786
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 337-814 3.16e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 3.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrdghDRHVLEMEAKMDQLRA 416
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA----EEELEEAEAELAEAEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRL--ESSKHI 494
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEeeEEEALE 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  495 DDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENS-- 572
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAga 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  573 -DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALK 651
Cdd:COG1196    526 vAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  652 AKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVKELD----------VLQAKCNEQTKLIGSLTQQI 721
Cdd:COG1196    605 ASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsaggslTGGSRRELLAALLEAEAELE 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  722 RASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK 801
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          490
                   ....*....|...
gi 2024359624  802 DSLEKELQLLKEK 814
Cdd:COG1196    763 EELERELERLERE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 867-1501 3.90e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.47  E-value: 3.90e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  867 REEREQQLTEAKVKLEND--IAEIMKSSGDSSAQLMKMNDELRLKE----RQLEQIQLELTKANEKAVQLQKNVEQTAQK 940
Cdd:PTZ00121  1194 RKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAeeakKAEEERNNEEIRKFEEARMAHFARRQAAIK 1273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  941 AEQSQQETLKTHQEELKKMQDqltdMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKN 1020
Cdd:PTZ00121  1274 AEEARKADELKKAEEKKKADE----AKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK 1349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1021 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKmrdliSEKETLAQErntLKLEKESLLSQHLEMESKillvqqdr 1100
Cdd:PTZ00121  1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK-----AEEKKKADE---AKKKAEEDKKKADELKKA-------- 1413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1101 EELWTKNEELnseNKKILKQKEAAEAKSRQESTEKVALISEKSKllseiETAQAdllkitqENDALRSSESTLLQQLKEL 1180
Cdd:PTZ00121  1414 AAAKKKADEA---KKKAEEKKKADEAKKKAEEAKKADEAKKKAE-----EAKKA-------EEAKKKAEEAKKADEAKKK 1478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1181 QANKDAVDVACQKHIKEREELEHYQKLLEENdrviKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERdsaQEKDLDL 1260
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEE---KKKADEL 1551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1261 KSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTE----LETEREKLEKMTKDNMD 1336
Cdd:PTZ00121  1552 KKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEeakkAEEAKIKAEELKKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1337 LKASLSSLSNFLEEMKSSREASNSEKIHLLQealfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINEL 1416
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1417 NLEKESVFSKSLQFEKHNEALLREKDELERKYSElldEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEE 1496
Cdd:PTZ00121  1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784


                   ....*
gi 2024359624 1497 LKKKN 1501
Cdd:PTZ00121  1785 LDEED 1789
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 607-1580 4.52e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.99  E-value: 4.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  607 QTAEFAELKTQMEKVKLDY-----ENEMSNLKLKQENEKSQHLKEI----EALKAKLLEVTEEKEQTLENLKAKLESVED 677
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQgqkvqEHQMELKYLKQYKEKACEIRDQitskEAQLESSREIVKSYENELDPLKNRLKEIEH 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  678 Q--HLVEMEDTLNKLQEAEIKVKeldvlqakcNEQTKLIGSLTQQIRASEEKLLDLAALQKAnsegklEIQKLSEQLQAA 755
Cdd:TIGR00606  260 NlsKIMKLDNEIKALKSRKKQME---------KDNSELELKMEKVFQGTDEQLNDLYHNHQR------TVREKERELVDC 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  756 EKQIQNLETEKVGGSSKVSNLTKElQGKEQklldleknLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 835
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVE-QGRLQ--------LQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNF 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  836 LNQKEEQFALMSSELEQLKSNLTvmetklkereEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 915
Cdd:TIGR00606  396 HTLVIERQEDEAKTAAQLCADLQ----------SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  916 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLtDMKKQMETSQNQYKDLQAKYEKETsEMITKH 995
Cdd:TIGR00606  466 LEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADL-DRKLRKLDQEMEQLNHHTTTRTQM-EMLTKD 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  996 DADikgfkqnllDAEEALKAAQKKNDELETQAEELKKQaeqaKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1075
Cdd:TIGR00606  544 KMD---------KDEQIRKIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHI 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1076 KLEKESLLSQHLEMESKILlvqqdrEELWTKNEELNSENKKilkqkeaaeaKSRQESTEKVALISEKSKLLSEIETaqad 1155
Cdd:TIGR00606  611 NNELESKEEQLSSYEDKLF------DVCGSQDEESDLERLK----------EEIEKSSKQRAMLAGATAVYSQFIT---- 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1156 llKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1235
Cdd:TIGR00606  671 --QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPE 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1236 QRELLQEVSILTAERDSAQEKDLDLKSThIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLAnTANENQALKLRKDE 1315
Cdd:TIGR00606  749 LRNKLQKVNRDIQRLKNDIEEQETLLGT-IMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQA-AKLQGSDLDRTVQQ 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1316 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAlfaseQRLLAEREELVNENKAVTEkL 1395
Cdd:TIGR00606  827 VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNL-----QRRQQFEEQLVELSTEVQS-L 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1396 TKATADAVLAETAFTEKINELNLEKESVFSKSlqfEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsa 1475
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSK---ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDY------ 971

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1476 krlLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSdllkEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEI 1555
Cdd:TIGR00606  972 ---LKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDID----TQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEM 1044

                          970       980
                   ....*....|....*....|....*
gi 2024359624 1556 LNRERTELQDKCQKLTGEVENMKEN 1580
Cdd:TIGR00606 1045 GQMQVLQMKQEHQKLEENIDLIKRN 1069
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1553-2074 4.68e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.00  E-value: 4.68e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1553 IEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMrEKNKEFLTEKELLVQ 1632
Cdd:PRK03918   171 IKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1633 EKEKSETKLEEVIK--EKMI--LYKETEQLASKIEQLKS------DFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEK 1702
Cdd:PRK03918   249 SLEGSKRKLEEKIRelEERIeeLKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1703 EkmelVQENESLHAEWKSLVIINEEILKEKEKLsKEYYKLHEKVVALLEQTD---ADFSCR--------LLVSEGKHELL 1771
Cdd:PRK03918   329 R----IKELEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELErlkKRLTGLtpeklekeLEELEKAKEEI 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1772 LEEMSNLALKLREIERLQAQ--TFMQKFEADKRA----------EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1839
Cdd:PRK03918   404 EEEISKITARIGELKKEIKElkKAIEELKKAKGKcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1840 KLQNELdmlkqnnlKNEEELTKSKELL----NLENK-------KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEEL 1908
Cdd:PRK03918   484 ELEKVL--------KKESELIKLKELAeqlkELEEKlkkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1909 GRSRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESTLK---------KEIDEERASLQKSISDTSALITQKDEEL 1978
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1979 EKLRNEITVLRGENASAKTLQSV--VKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLlqdESAEDKQQE 2056
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL---EEREKAKKE 712

                          570
                   ....*....|....*...
gi 2024359624 2057 IDFLNSVIVDLQRRNEEL 2074
Cdd:PRK03918   713 LEKLEKALERVEELREKV 730
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
790-985 4.89e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 61.57  E-value: 4.89e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  790 LEKNLSAVNQVKDSLEKELQLLKEKftsaVDGAENAQRAMQETiNKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 869
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKE----LEEAEAALEEFRQK-NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  870 REQQLTEAKVKLENDIAEIMkssgdSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVE-------------- 935
Cdd:COG3206    241 RLAALRAQLGSGPDALPELL-----QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAalraqlqqeaqril 315

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  936 -------QTAQKAEQSQQETLKTHQEELKKM---QDQLTDMKKQMETSQNQYKDLQAKYE 985
Cdd:COG3206    316 asleaelEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLE 375
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1126-1923 5.69e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.62  E-value: 5.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1126 AKSRQESTEKVALISEKSkllSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvACQKHIKEREELEHYQ 1205
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFD---RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1206 KL--LEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS-THIALKNEIDCLLQTNRSLQ 1282
Cdd:TIGR02169  228 LLkeKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1283 SEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEM----KSSREAS 1358
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1359 NSEKIHLlqEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALL 1438
Cdd:TIGR02169  388 KDYREKL--EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1439 REKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKK--------KNLENQELIAC 1510
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1511 RSDLS------------------DLLKEAQDARRTL--------ENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQ 1564
Cdd:TIGR02169  542 EVAAGnrlnnvvveddavakeaiELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFG 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1565 DkcqklTGEVENMKENLTVEKKARILDKESFLLER-----------MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQE 1633
Cdd:TIGR02169  622 D-----TLVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1634 KEK--------------SETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhscvsvMLDELQHKYEV 1699
Cdd:TIGR02169  697 LRRienrldelsqelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS-------ELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1700 TEKEKMELVQENESLHAEwkslviINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLvsegKHELLLEEMSNLA 1779
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEAR------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL----EKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1780 LKLREIErlqaqtfmqkfeaDKRAEevlqtmekVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEEL 1859
Cdd:TIGR02169  840 EQRIDLK-------------EQIKS--------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624 1860 TKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEE 1923
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1321-1962 7.23e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 7.23e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1321 ETEReKLEKmTKDNMD--------LKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRL-LAEREELVNENKAV 1391
Cdd:COG1196    176 EAER-KLEA-TEENLErledilgeLERQLEPLE---------RQAEKAERYRELKEELKELEAELlLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1392 TEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQEl 1471
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1472 dfsAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1551
Cdd:COG1196    324 ---ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1552 DIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLV 1631
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1632 QEKEKSETKLEEvikekmilyKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQEN 1711
Cdd:COG1196    481 ELLEELAEAAAR---------LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1712 eslhaewkslVIINEEILKEKEKLSKEYyKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ 1791
Cdd:COG1196    552 ----------VVEDDEVAAAAIEYLKAA-KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1792 TFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdmlkqnnLKNEEELTKSKELLNLENK 1871
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL-------LEAEAELEELAERLAEEEL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1872 KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtsHQKLEEERSVLNNQLLEMKKSLPSntlrESTLKK 1951
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL--LEELLEEEELLEEEALEELPEPPD----LEELER 767

                          650
                   ....*....|.
gi 2024359624 1952 EIDEERASLQK 1962
Cdd:COG1196    768 ELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 903-1135 8.12e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 8.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  903 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQE------TLKTHQEELKKMQDQLTDMKKQMETSQNQ 976
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaalarRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  977 YKDLQAKYEKETSEMITKHDADIKGF---KQNLLDAEEALKAAQKKNDELETQAEELKKQAEQakslssvLASARKEIEL 1053
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-------LAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1054 MSDKMRDLISEKETLAQERNTLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQEST 1133
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ..
gi 2024359624 1134 EK 1135
Cdd:COG4942    249 AA 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
941-1186 9.17e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 60.80  E-value: 9.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  941 AEQSQQETLKTHQEELKK----MQDQLTDMKKQMETSQNQYKDLQAKYeketsemitkhdadikgfkqNLLDAEEALKAA 1016
Cdd:COG3206    158 AEAYLEQNLELRREEARKalefLEEQLPELRKELEEAEAALEEFRQKN--------------------GLVDLSEEAKLL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1017 QKKNDELETQAEELKKQAEQAKSLssvLASARKEIELMSDKMRDLISEKE--TLAQERNTLKLEKESLLSQHLEMESKIL 1094
Cdd:COG3206    218 LQQLSELESQLAEARAELAEAEAR---LAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1095 LVQQDREELwtkNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL 1174
Cdd:COG3206    295 ALRAQIAAL---RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371

                          250
                   ....*....|..
gi 2024359624 1175 QQLKELQANKDA 1186
Cdd:COG3206    372 QRLEEARLAEAL 383
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
423-890 1.02e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 1.02e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  423 REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIDDV----- 497
Cdd:PRK03918   217 PELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKaeeyi 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  498 ------DTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEE--ALRKEIKTLSASNERMGKENESLKTKLDHANK 569
Cdd:PRK03918   297 klsefyEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEElkKKLKELEKRLEELEERHELYEEAKAKKEELER 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  570 ENSDVIELWKSKLESAIASHQQAMEELKVSFNK---GVGAQTAEFAELKTQMEKVK-LDYENEMSNLKLKQENEK---SQ 642
Cdd:PRK03918   377 LKKRLTGLTPEKLEKELEELEKAKEEIEEEISKitaRIGELKKEIKELKKAIEELKkAKGKCPVCGRELTEEHRKellEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  643 HLKEIEALKAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IG 715
Cdd:PRK03918   457 YTAELKRIEKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLI 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  716 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLS 795
Cdd:PRK03918   536 KLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEK 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  796 AVNQVKDSLEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 873
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREE 691

                          490
                   ....*....|....*..
gi 2024359624  874 LTEAKVKLENDIAEIMK 890
Cdd:PRK03918   692 IKKTLEKLKEELEEREK 708
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 794-1048 1.04e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  794 LSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 873
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  874 LTEAKVKLENDIAEImkssgdssaqlmkmndeLRLKERQLEQIQLELTKANEKAVQLQKNVE--QTAQKAEQSQQETLKT 951
Cdd:COG4942     95 LRAELEAQKEELAEL-----------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  952 HQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1031
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233

                          250
                   ....*....|....*..
gi 2024359624 1032 KQAEQAKSLSSVLASAR 1048
Cdd:COG4942    234 AEAAAAAERTPAAGFAA 250
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 529-1180 1.04e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.75  E-value: 1.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  529 KEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSKLESAIASHQQAMEELKVSfnkgvgAQT 608
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI--EELRAQEAVLEETQERINRA------RKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  609 AEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKLLEVtEEKEQTLENLKAKLESVEDQHLV------- 681
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQ-SKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLHSQEIHIRDAHEVatsirei 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  682 ---EMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 758
Cdd:TIGR00618  371 scqQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  759 IQNLETEK---VGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT------SAVDGAENAQRAM 829
Cdd:TIGR00618  451 AQCEKLEKihlQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpnparQDIDNPGPLTRRM 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  830 QETINKLNQKEEQFALMSSELEQLKSNLTvmetKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND-ELRL 908
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDVYHQLTSERKQRA----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEkLSEA 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  909 KERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL-QAKYEKE 987
Cdd:TIGR00618  607 EDMLACEQHALLRKLQPEQDLQDVRLHL-QQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrQLALQKM 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  988 TSEmitkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQaksLSSVLASARKEIELMSDKMRDLISEKE- 1066
Cdd:TIGR00618  686 QSE------------KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE---IENASSSLGSDLAAREDALNQSLKELMh 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1067 ---------TLAQERNTLKLEKESLLSQHL-----EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQES 1132
Cdd:TIGR00618  751 qartvlkarTEAHFNNNEEVTAALQTGAELshlaaEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEE 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359624 1133 TEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1180
Cdd:TIGR00618  831 EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
774-1337 1.14e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  774 SNLTKELQGKEQKllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQramqETINKLNQKEEQFALMSSELEQL 853
Cdd:PRK02224   190 DQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEAD----EVLEEHEERREELETLEAEIEDL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  854 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 933
Cdd:PRK02224   264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  934 VEQTAQKAEQSQQETlKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEAL 1013
Cdd:PRK02224   344 AESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIE-ELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1014 KAAQKKNDELETQAEELKKQAEQAKSL----------SSVLASARKE-IELMSDKMRDLISEKETLAQERNTLKlEKESL 1082
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALleagkcpecgQPVEGSPHVEtIEEDRERVEELEAELEDLEEEVEEVE-ERLER 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1083 LSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQE 1162
Cdd:PRK02224   501 AEDLVEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1163 NDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD----LARNQRE 1238
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEarieEAREDKE 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1239 LLQE-VSILTAERDSAQEKDLDLKSTHIALKNEIDCLlqtnRSLQSEKEMLLKSREELcVSLANTANENQAL--KLRKDE 1315
Cdd:PRK02224   657 RAEEyLEQVEEKLDELREERDDLQAEIGAVENELEEL----EELRERREALENRVEAL-EALYDEAEELESMygDLRAEL 731

                          570       580
                   ....*....|....*....|..
gi 2024359624 1316 MQTELETerekLEKMTKDNMDL 1337
Cdd:PRK02224   732 RQRNVET----LERMLNETFDL 749
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 469-1184 1.21e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 60.22  E-value: 1.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  469 ELERDLALRVKEVAELRGRLESSKHIDDVDTSLSL----LQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIK 544
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQEENQHLQLtiqaLQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFR 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  545 TLSASNERMGKENESLKTKLDHANKEnsdvIELWKSKLESAIASHQQAMEELK--------VSFNKGVGAQTAEfAELKT 616
Cdd:pfam10174  120 RLQSEHERQAKELFLLRKTLEEMELR----IETQKQTLGARDESIKKLLEMLQskglpkksGEEDWERTRRIAE-AEMQL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  617 QMEKVKLDyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIK 696
Cdd:pfam10174  195 GHLEVLLD-QKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  697 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLL----DLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggssk 772
Cdd:pfam10174  274 IKQMEVYKSHSKFMKNKIDQLKQELSKKESELLalqtKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTE------- 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  773 VSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 852
Cdd:pfam10174  347 VDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKS 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  853 LKSN-------LTVMETKLKEREE-----REQQLTEAKVKLEnDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLEL 920
Cdd:pfam10174  427 LQTDssntdtaLTTLEEALSEKERiierlKEQREREDRERLE-ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHA 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  921 T-------KANEKAVQLQKNVEQTAQKAEQSQQETLKTHQ-EELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 991
Cdd:pfam10174  506 SslassglKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNaEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLl 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  992 -ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSsVLASARKEIELMSDKMRDLISEKETLAQ 1070
Cdd:pfam10174  586 gILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQ-LLEEARRREDNLADNSQQLQLEELMGAL 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1071 ERNTLKLEkesllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKqkEAAEAKsrQESTekVALISEKSKLLSEIE 1150
Cdd:pfam10174  665 EKTRQELD---------ATKARLSSTQQSLAEKDGHLTNLRAERRKQLE--EILEMK--QEAL--LAAISEKDANIALLE 729

                          730       740       750
                   ....*....|....*....|....*....|....
gi 2024359624 1151 TAQADLLKITQENDALRSSESTLLQQLKELQANK 1184
Cdd:pfam10174  730 LSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1778-2056 1.29e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1778 LALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEE 1857
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1858 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKK 1937
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---EEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1938 SLPSNTLRESTLKKEIDE---ERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEE 2014
Cdd:COG1196    373 ELAEAEEELEELAEELLEalrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359624 2015 KVKNLEQKLKAKSEQPLTVTsPSGDIAANLLQDESAEDKQQE 2056
Cdd:COG1196    453 ELEEEEEALLELLAELLEEA-ALLEAALAELLEELAEAAARL 493
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1082-1925 1.92e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1082 LLSQHLEMESKILLVQQDREElwtkNEELNSENKKILKQKEAAEAKS----RQESTEKVALISEKSKLLSEIETAQADLL 1157
Cdd:pfam02463  125 LESQGISPEAYNFLVQGGKIE----IIAMMKPERRLEIEEEAAGSRLkrkkKEALKKLIEETENLAELIIDLEELKLQEL 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1158 KIT-QENDALRSSESTLLQQLKELQANKDAVDVACQKHIKE-REELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1235
Cdd:pfam02463  201 KLKeQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1236 QRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDE 1315
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1316 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKS--SREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTE 1393
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1394 KLTKATADAVLAETAFTEKINELNLEKESVF------SKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR 1467
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEdllketQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1468 EQELDFSAKRLLVQENTTLKYS---IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1544
Cdd:pfam02463  521 GGRIISAHGRLGDLGVAVENYKvaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1545 SFNTCSSDIEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1624
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVV-EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1625 TEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1704
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1705 MELVQ------------ENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRL--LVSEGKHEL 1770
Cdd:pfam02463  760 EEKEEekselslkekelAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkiKEEELEELA 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1771 LLEEMSNLALKLREIErlqaqTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQ 1850
Cdd:pfam02463  840 LELKEEQKLEKLAEEE-----LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1851 NNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEER 1925
Cdd:pfam02463  915 KENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEER 989
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 429-1125 3.29e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 58.88  E-value: 3.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  429 LNQLEEEKRKVEDLQFRVEEEsitkgdlevatvseksrIMELERDLALRVKEVAELRGRLESSKhiddvDTSLSLLQEIS 508
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTE-----------------IKKKEKELEKLNNKYNDLKKQKEELE-----NELNLLEKEKL 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  509 SLQEKMAAAGKEHQRemsslKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKEnsdvielwKSKLESAIAS 588
Cdd:TIGR04523  184 NIQKNIDKIKNKLLK-----LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQE--------INEKTTEISN 250

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  589 HQQAMEELKVSFNKgvgaqtaefaeLKTQMEKVKLDYENemSNLKLKQENeksqhlKEIEALKAKLLEVTEEKEQ-TLEN 667
Cdd:TIGR04523  251 TQTQLNQLKDEQNK-----------IKKQLSEKQKELEQ--NNKKIKELE------KQLNQLKSEISDLNNQKEQdWNKE 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  668 LKAKLESVEdqhlvemedtlnklqeaeikvKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDL----AALQKANSEGKL 743
Cdd:TIGR04523  312 LKSELKNQE---------------------KKLEEIQNQISQNNKIISQLNEQISQLKKELTNSesenSEKQRELEEKQN 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  744 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNlsavnqvKDSLEKELQLLKEKFT---SAVD 820
Cdd:TIGR04523  371 EIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE-------KELLEKEIERLKETIIknnSEIK 443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  821 GAENAQRAMQETINKLNQK----EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 896
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTreslETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLK 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  897 AQLMKMNDELRLKERQLEQIQLELTKANE--KAVQLQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQLTDMKKQMETSQ 974
Cdd:TIGR04523  524 EKIEKLESEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKNKEIEE-----LKQTQKSLKKKQEEKQELIDQKEKEK 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  975 NQYKDLQAKYEKETSEMitkhdadikgfkqnlldaEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELM 1054
Cdd:TIGR04523  599 KDLIKEIEEKEKKISSL------------------EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1055 SDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAE 1125
Cdd:TIGR04523  661 WPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKELE 731
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1305-1883 4.27e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 4.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1305 ENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNsEKIHLLQEAlfasEQRLLAEREEL 1384
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAE----EYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1385 VNENKAVTEKLTkatadavlaetAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSD 1464
Cdd:COG1196    301 EQDIARLEERRR-----------ELEERLEELEEELA-------ELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1465 MKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1544
Cdd:COG1196    363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1545 SFNTCSSDIEILNRERTELQDKcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1624
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLEL-LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1625 TEKEL--LVQEKEKSETKLEEVIKEKM--ILYKETEQLASKIEQLKSD------FTSLSVSKAE--LEDVHSCVSVMLDE 1692
Cdd:COG1196    522 LAGAVavLIGVEAAYEAALEAALAAALqnIVVEDDEVAAAAIEYLKAAkagratFLPLDKIRARaaLAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1693 LQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKlskeyyklHEKVVALLEQTDADFScRLLVSEGKHELLL 1772
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA--------GRLREVTLEGEGGSAG-GSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1773 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1852
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2024359624 1853 LKNEEELTKSKELlnleNKKVEELKKEFEAL 1883
Cdd:COG1196    753 LEELPEPPDLEEL----ERELERLEREIEAL 779
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 656-1593 4.30e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 58.65  E-value: 4.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  656 EVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKE-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA- 733
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESE-LKELEKKHQQLCEEKNALQEqLQAETELCAEAEEMRARLAARKQELEEILHELESr 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  734 ----------LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLtkelqgkEQKLLDLEKNLSAVNQVKDS 803
Cdd:pfam01576   84 leeeeersqqLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL-------EEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  804 LEKELQLLKEKFTSAVDGAENaqramqetINKLNQKEEqfalmsseleqlkSNLTVMETKLKEREEREQQLTEAKVKLEN 883
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKS--------LSKLKNKHE-------------AMISDLEERLKKEEKGRQELEKAKRKLEG 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  884 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV-EQTAQKAEqsQQETLKTHQEELKKMQDQ 962
Cdd:pfam01576  216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIrELEAQISE--LQEDLESERAARNKAEKQ 293

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  963 LTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQA-EELKKQAEQAKSLS 1041
Cdd:pfam01576  294 RRDLGEELEALKTELEDTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1042 SVLASARKEIElmsDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSE-------- 1113
Cdd:pfam01576  373 ANLEKAKQALE---SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesvssll 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1114 ----NKKILKQKEAAEAKSR---------QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL--- 1177
Cdd:pfam01576  450 neaeGKNIKLSKDVSSLESQlqdtqellqEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLsdm 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1178 -KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL---------- 1246
Cdd:pfam01576  530 kKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLekkqkkfdqm 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1247 -----------TAERDSAQEKDLDLKSTHIALKNEIDCLL-------QTNRSLQSEKEMLLKSREELCVSLANTANENQA 1308
Cdd:pfam01576  610 laeekaisaryAEERDRAEAEAREKETRALSLARALEEALeakeeleRTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1309 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAER------- 1381
Cdd:pfam01576  690 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERkqraqav 769

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1382 ------EELVNENKAVTEKLTKATADAV-------LAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKY 1448
Cdd:pfam01576  770 aakkklELDLKELEAQIDAANKGREEAVkqlkklqAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDL 849

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1449 SELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLeNQELiacrsdLSDLLKEAQDARRTL 1528
Cdd:pfam01576  850 AASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS-NTEL------LNDRLRKSTLQVEQL 922

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1529 ENELAAVSHAKQVLSSSFNTcssdieiLNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1593
Cdd:pfam01576  923 TTELAAERSTSQKSESARQQ-------LERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLE 980
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
827-1248 5.23e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  827 RAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEIMKSSGDSSAQLMKMNDEL 906
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  907 RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEK 986
Cdd:COG4717    152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  987 ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVL--------ASARKEIELMSDKM 1058
Cdd:COG4717    232 LENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLflllarekASLGKEAEELQALP 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1059 RDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK--EAAEAKSRQESTEKV 1136
Cdd:COG4717    312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1137 ALISEKSKLLSEIETAQADLLKITQENDALRS--SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRv 1214
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE- 470

                          410       420       430
                   ....*....|....*....|....*....|....
gi 2024359624 1215 ikdkddvIQRLQSSYDDLARNQRELLQEVSILTA 1248
Cdd:COG4717    471 -------LAELLQELEELKAELRELAEEWAALKL 497
PTZ00121 PTZ00121
MAEBL; Provisional
 1348-2021 7.09e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 7.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1348 LEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAfTEKINELNLEKESVFSKS 1427
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKA 1292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1428 LQFEKHNEAL----LREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLE 1503
Cdd:PTZ00121  1293 DEAKKAEEKKkadeAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1504 NQEliaCRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTV 1583
Cdd:PTZ00121  1373 KEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1584 EKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-----KNKEFLTEKELLVQEKEKSETKLEEVIKEKMilYKETEQL 1658
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1659 ASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK----MELVQENESLHAEWKSLVIINEEILKEKEK 1734
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1735 LSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVT 1814
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1815 KEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQL 1894
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1895 AALQEENVKLAEELGRSRDEVTSHQKLEEERSVlnNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQK 1974
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359624 1975 DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQ 2021
Cdd:PTZ00121  1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK 1892
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 789-2021 7.15e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 58.14  E-value: 7.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKdsleKELQLLKEkFTSAVDGAENAQRAMQETINKLNQKEEQF--ALMSSELEQ-LKSNLTVM----E 861
Cdd:TIGR01612  484 DIDENSKQDNTVK----LILMRMKD-FKDIIDFMELYKPDEVPSKNIIGFDIDQNikAKLYKEIEAgLKESYELAknwkK 558

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  862 TKLKEREEREQQlTEAKVKLENDIAEIMKssgdssaQLMKMNDEL----RLKERQLEQIQlELTKANE---KAVQLQKNV 934
Cdd:TIGR01612  559 LIHEIKKELEEE-NEDSIHLEKEIKDLFD-------KYLEIDDEIiyinKLKLELKEKIK-NISDKNEyikKAIDLKKII 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  935 EQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKqmETSQNQYKDLQAKYeKETSEMITKHDADIKGFKQNLLDAEEALK 1014
Cdd:TIGR01612  630 ENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKS--ELSKIYEDDIDALY-NELSSIVKENAIDNTEDKAKLDDLKSKID 706

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1015 AAQKKNDELETQAEELkkqaeqakSLSSvlasarkeIELMSDKMRDLISE--KETLAQERNTLKLEKESLLSQHLEMESK 1092
Cdd:TIGR01612  707 KEYDKIQNMETATVEL--------HLSN--------IENKKNELLDIIVEikKHIHGEINKDLNKILEDFKNKEKELSNK 770

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1093 IllvqqdrEELWTKNEELNSENKKILKQKEAAEAKSRQEST--EKVALISEKSK-LLSEIETAQADLLKITQEndalrss 1169
Cdd:TIGR01612  771 I-------NDYAKEKDELNKYKSKISEIKNHYNDQINIDNIkdEDAKQNYDKSKeYIKTISIKEDEIFKIINE------- 836

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1170 estlLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleeNDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSiltae 1249
Cdd:TIGR01612  837 ----MKFMKDDFLNKVDKFINFENNCKEKIDSEHEQF----AELTNKIKAEISDDKLNDYEKKFNDSKSLINEIN----- 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1250 rdSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEK 1329
Cdd:TIGR01612  904 --KSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDK 981

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1330 MTKDnmdlkASLSSLsnfleemkssrEASNSEKIHL---LQEALFASEQRLL----AEREELVNEnkaVTEKLTKATADA 1402
Cdd:TIGR01612  982 AFKD-----ASLNDY-----------EAKNNELIKYfndLKANLGKNKENMLyhqfDEKEKATND---IEQKIEDANKNI 1042

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1403 VLAETAFTEKINELNLEKESVFSKSLqfEKHNEALLREKDELERKYSELlDEKKSLENaFSDMKREQELDFS-----AKR 1477
Cdd:TIGR01612 1043 PNIEIAIHTSIYNIIDEIEKEIGKNI--ELLNKEILEEAEINITNFNEI-KEKLKHYN-FDDFGKEENIKYAdeinkIKD 1118

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1478 LLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEA------QDARRTLENELAAVSHAKQVLSSsFNTCSS 1551
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAisnddpEEIEKKIENIVTKIDKKKNIYDE-IKKLLN 1197

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1552 DIEILNRERTELQdkcqkltgEVENMkeNLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-KNKEFLTEKELL 1630
Cdd:TIGR01612 1198 EIAEIEKDKTSLE--------EVKGI--NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEiKEKSPEIENEMG 1267

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1631 VQEKEKSETKLEEV----IKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDV--------------HSCVSVMLDE 1692
Cdd:TIGR01612 1268 IEMDIKAEMETFNIshddDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIkkelqknlldaqkhNSDINLYLNE 1347

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1693 LQHKYEVTEKEKM--------ELVQENESLHAEWKSLVIINEEILKE-KEKLSKEYYKlhEKVVALLEQTDADfSCRLLV 1763
Cdd:TIGR01612 1348 IANIYNILKLNKIkkiidevkEYTKEIEENNKNIKDELDKSEKLIKKiKDDINLEECK--SKIESTLDDKDID-ECIKKI 1424

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1764 SEGKHELLLEEMSNLAL--KLREIERLQAQTFMQKFEADKRAEEVLQTmekvtkEKDAIHQEKIETLASLENSRQTNEKL 1841
Cdd:TIGR01612 1425 KELKNHILSEESNIDTYfkNADENNENVLLLFKNIEMADNKSQHILKI------KKDNATNDHDFNINELKEHIDKSKGC 1498

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1842 QNELDmlkqnnlKNEEELTKSKELLNLENKKVEELKKEFEALKL------AAAQKSQQLAALQEENVKLAEELGRSRDEV 1915
Cdd:TIGR01612 1499 KDEAD-------KNAKAIEKNKELFEQYKKDVTELLNKYSALAIknkfakTKKDSEIIIKEIKDAHKKFILEAEKSEQKI 1571

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1916 TS--HQKLEEERSVLNNQ-----LLEMKKSL---PSNTLRESTLKKEIDE---ERASLQKSISDTSalITQKDEELEKLR 1982
Cdd:TIGR01612 1572 KEikKEKFRIEDDAAKNDksnkaAIDIQLSLenfENKFLKISDIKKKINDclkETESIEKKISSFS--IDSQDTELKENG 1649

                         1290      1300      1310
                   ....*....|....*....|....*....|....*....
gi 2024359624 1983 NEITvlrgenasakTLQSVVKTLESDKLKLEEKVKNLEQ 2021
Cdd:TIGR01612 1650 DNLN----------SLQEFLESLKDQKKNIEDKKKELDE 1678
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2149-2165 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359624 2149 RPYCDTCEMFGHWTADC 2165
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1431-1985 1.09e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1431 EKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsakRLLVQENTTLKYSIEALEEELKKKNLENQELIAC 1510
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL-------AELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1511 RSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKAR-- 1588
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELae 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1589 -ILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKS 1667
Cdd:COG1196    377 aEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1668 DFTSLSVSKAELEDVHSCVSVMLDELQHKYEvtEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLH--EK 1745
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELA--EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgvEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1746 VVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKI 1825
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1826 ETL--ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1903
Cdd:COG1196    615 YYVlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1904 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRN 1983
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774


                   ..
gi 2024359624 1984 EI 1985
Cdd:COG1196    775 EI 776
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 904-1102 1.54e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.99  E-value: 1.54e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  904 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDlQAK 983
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQAEIAEAEAEIEERREELGE-RAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  984 YEKETSEMITKHDA-----DIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1058
Cdd:COG3883     94 ALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359624 1059 RDLISEKE----TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREE 1102
Cdd:COG3883    174 EAQQAEQEallaQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 406-1506 1.64e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 56.98  E-value: 1.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVedlqFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAE-- 483
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDS----IHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNISDkn 616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  484 --LRGRLESSKHIDDVDTSLSLLQEISSLQ--EKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKEN-- 557
Cdd:TIGR01612  617 eyIKKAIDLKKIIENNNAYIDELAKISPYQvpEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKENAIDNTEDka 696

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  558 --ESLKTKLDHA-----NKENSDV------IELWKSKLESAIASHQQAME-ELKVSFNKGVGAQTAEFAELKTQMEKVKl 623
Cdd:TIGR01612  697 klDDLKSKIDKEydkiqNMETATVelhlsnIENKKNELLDIIVEIKKHIHgEINKDLNKILEDFKNKEKELSNKINDYA- 775

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  624 DYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAkLESVEDQHLVEMEDTLNKLQEAEIKVKELDVL 703
Cdd:TIGR01612  776 KEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKT-ISIKEDEIFKIINEMKFMKDDFLNKVDKFINF 854

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  704 QAKCNEQT----KLIGSLTQQIRA--SEEKLLDLAalQKANSEGKLeiqkLSEQLQAAEKQIQNLET-EKVGGSSKVSNL 776
Cdd:TIGR01612  855 ENNCKEKIdsehEQFAELTNKIKAeiSDDKLNDYE--KKFNDSKSL----INEINKSIEEEYQNINTlKKVDEYIKICEN 928

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  777 TKElqgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE------- 849
Cdd:TIGR01612  929 TKE---------SIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASLNDYEaknneli 999

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  850 --LEQLKSNL-----TVMETKLKEREEREQQLTEAKVKLENDIAEI-------MKSSGDSSAQLMKMNDELrLKERQLEQ 915
Cdd:TIGR01612 1000 kyFNDLKANLgknkeNMLYHQFDEKEKATNDIEQKIEDANKNIPNIeiaihtsIYNIIDEIEKEIGKNIEL-LNKEILEE 1078

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  916 IQLELTKANEKAVQLqknveQTAQKAEQSQQETLKtHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKH 995
Cdd:TIGR01612 1079 AEINITNFNEIKEKL-----KHYNFDDFGKEENIK-YADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQI 1152

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  996 DaDIKGFKQNLLdAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLAsarkEIELMSDKMRDLISEKETLAQERNTL 1075
Cdd:TIGR01612 1153 N-DLEDVADKAI-SNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIA----EIEKDKTSLEEVKGINLSYGKNLGKL 1226

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1076 KLEK---ESLLSQHL--EMESKIllvqQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS--KLLSE 1148
Cdd:TIGR01612 1227 FLEKideEKKKSEHMikAMEAYI----EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKhdENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1149 IETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK-----------HIKE-REELEHYQKLLEENDRVIK 1216
Cdd:TIGR01612 1303 IREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEianiynilklnKIKKiIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1217 DKDDVIQRL-QSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREel 1295
Cdd:TIGR01612 1383 DELDKSEKLiKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIE-- 1460

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1296 cvsLANTANEnQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfASEQ 1375
Cdd:TIGR01612 1461 ---MADNKSQ-HILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNK---YSAL 1533

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1376 RLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREK---DELERKYSELL 1452
Cdd:TIGR01612 1534 AIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQlslENFENKFLKIS 1613

                         1130      1140      1150      1160      1170      1180
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1453 DEKKSLENAFSDM----KREQELDFSAKRLLVQENTTLKYSIEALEEELK--KKNLENQE 1506
Cdd:TIGR01612 1614 DIKKKINDCLKETesieKKISSFSIDSQDTELKENGDNLNSLQEFLESLKdqKKNIEDKK 1673
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 354-1085 1.75e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALV---RDGHDRHVLEMEAKMDQLRAMVEAADREKVELLN 430
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQeeeLKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  431 QLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELE-RDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISS 509
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEkLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  510 LQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASH 589
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  590 QQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLK 669
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  670 AKLESV--------------------------------------EDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT 711
Cdd:pfam02463  562 ERQKLVraltelplgarklrllipklklplksiavleidpilnlAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  712 KLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 791
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  792 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ--LKSNLTVMETKLKEREE 869
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKteKLKVEEEKEEKLKAQEE 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  870 REqqltEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV----EQTAQKAEQSQ 945
Cdd:pfam02463  802 EL----RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEitkeELLQELLLKEE 877

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  946 QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELET 1025
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1026 QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1085
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 556-1342 3.26e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 55.88  E-value: 3.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  556 ENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKvsfnKGVGAQTAEFAELKTQMEKVKLDYENEMS-NLKL 634
Cdd:pfam05483   71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENR----KIIEAQRKAIQELQFENEKVSLKLEEEIQeNKDL 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  635 KQENEKSQH----LKEIEALKAKLLEVTE-EKEQT----------LENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKE 699
Cdd:pfam05483  147 IKENNATRHlcnlLKETCARSAEKTKKYEyEREETrqvymdlnnnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQH 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  700 LDV-LQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKansEGKLEIQKLSEQLQAAEKQIQNLETEKvggsskvSNLTK 778
Cdd:pfam05483  227 LEEeYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLE---ESRDKANQLEEKTKLQDENLKELIEKK-------DHLTK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  779 ELQgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENaqramqeTINKLNQKEEQFALMSSELEQLKSNLT 858
Cdd:pfam05483  297 ELE-------DIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA-------QMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  859 -VMETKLKEREEREQQLTEAKVKLENdiaeimkssgdSSAQLMKMNDELRLKERQLEQIQLELTKaNEKAVQLQKNVEQT 937
Cdd:pfam05483  363 eLLRTEQQRLEKNEDQLKIITMELQK-----------KSSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  938 AQKAEQSQQET---LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfkqnlldaeealk 1014
Cdd:pfam05483  431 AEELKGKEQELiflLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKE--------------------------- 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1015 aaQKKNDELETQAEEL----KKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhleme 1090
Cdd:pfam05483  484 --KLKNIELTAHCDKLllenKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESV-------- 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1091 skillvqqdREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSE 1170
Cdd:pfam05483  554 ---------REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKG 624

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1171 STLLQQLK--ELQANKDAVDVACQKHiKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTA 1248
Cdd:pfam05483  625 SAENKQLNayEIKVNKLELELASAKQ-KFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIA 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1249 ERDSAQEKDldlKSTHIALKNEIDCLLQTNRSLQSEKEMLlksREELCVSLANTANENQALKlrkdemqTELETEREKLE 1328
Cdd:pfam05483  704 EMVALMEKH---KHQYDKIIEERDSELGLYKNKEQEQSSA---KAALEIELSNIKAELLSLK-------KQLEIEKEEKE 770

                          810
                   ....*....|....
gi 2024359624 1329 KMTKDNMDLKASLS 1342
Cdd:pfam05483  771 KLKMEAKENTAILK 784
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
625-1088 3.53e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 3.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  625 YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE------EKEQTLENLKAKLESVEDQ--HLVEMEDTLNKLQEAEIK 696
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEkeeeyaELQEELEELEEELEELEAEleELREELEKLEKLLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  697 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSN 775
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  776 LTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKS 855
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  856 NLTVMETKLKEREEREQQLTEAKVKLEN-DIAEIMKSSGDSSAQLmkmNDELRLKERQLEQIQLELTKANEKAVQLQknv 934
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEeELEELLAALGLPPDLS---PEELLELLDRIEELQELLREAEELEEELQ--- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  935 eqtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDA-DIKGFKQNLLDAEEAL 1013
Cdd:COG4717    365 ---LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAlDEEELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1014 KAAQKKNDELETQAEELKKQAEQAKSlSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKEsLLSQHLE 1088
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEE-DGELAELLQELE-------ELKAELRELAEEWAALKLALE-LLEEARE 507
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 938-1182 3.56e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  938 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAAQ 1017
Cdd:COG4942     19 ADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKALLKQLAALERR--------IAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1018 KKNDELETQAEELKKQ-AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhlemeskillv 1096
Cdd:COG4942     90 KEIAELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL-------------- 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1097 QQDREELWTKNEELNSEnkkiLKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQ 1176
Cdd:COG4942    156 RADLAELAALRAELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELA---ELAAELAELQQEAEELEAL 228


                   ....*.
gi 2024359624 1177 LKELQA 1182
Cdd:COG4942    229 IARLEA 234
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1788-2102 3.70e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.85  E-value: 3.70e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1788 LQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqeKIETLASLENSRQ-------TNEKLQNELDMLKQNNLKNEEELT 1860
Cdd:COG5022    765 LQALKRIKKIQVIQHGFRLRRLVDYELKWRLFI---KLQPLLSLLGSRKeyrsylaCIIKLQKTIKREKKLRETEEVEFS 841

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1861 KSKELLNLENKKVEELKKEFEALKlaaaqKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1940
Cdd:COG5022    842 LKAEVLIQKFGRSLKAKKRFSLLK-----KETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLS 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1941 SNTLRESTLKKEID--EERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKN 2018
Cdd:COG5022    917 SDLIENLEFKTELIarLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKN 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 2019 LEQKLKAKSEQPLTVTSPSGDiaANLLQDESAEdKQQEIDFLNSVIVDLQRRNEELNLKiqRMCEAALNGNEEETINYDS 2098
Cdd:COG5022    997 FKKELAELSKQYGALQESTKQ--LKELPVEVAE-LQSASKIISSESTELSILKPLQKLK--GLLLLENNQLQARYKALKL 1071


                   ....
gi 2024359624 2099 EEEG 2102
Cdd:COG5022   1072 RREN 1075
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 834-1471 3.76e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.41  E-value: 3.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  834 NKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL 913
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  914 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQeELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEmIT 993
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK-ELEKLNNKYNDLKKQKE----ELENELNLLEKEKLN-IQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  994 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslssvlasarKEIELMSDKMRDLISEKETLAQERN 1073
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK----------DNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1074 TLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETaq 1153
Cdd:TIGR04523  257 QLKDEQNKIKKQ---LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSE---LKNQEKKLEEIQN-- 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1154 adllKITQENDALRSSESTlLQQLKELQANKDAVDVACQKHIKERE-ELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDL 1232
Cdd:TIGR04523  329 ----QISQNNKIISQLNEQ-ISQLKKELTNSESENSEKQRELEEKQnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1233 ARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLR 1312
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1313 KDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEK------IHLLQEALFASEQRLLAER-EELV 1385
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskISDLEDELNKDDFELKKENlEKEI 563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1386 NENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDM 1465
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643


                   ....*.
gi 2024359624 1466 KREQEL 1471
Cdd:TIGR04523  644 KQEVKQ 649
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
633-1052 5.31e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.31e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  633 KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTK 712
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-----EKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  713 LIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 791
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  792 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREERE 871
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  872 QQLTEAKVKLEN-DIAEIMKSSG--------------DSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ 936
Cdd:COG4717    307 LQALPALEELEEeELEELLAALGlppdlspeellellDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  937 TAQKAEQSQQetLKTHQEELKKMQDQLTDMKKQMET--SQNQYKDLQAKYE------KETSEMITKHDADIKGFKQNLLD 1008
Cdd:COG4717    387 LRAALEQAEE--YQELKEELEELEEQLEELLGELEEllEALDEEELEEELEeleeelEELEEELEELREELAELEAELEQ 464

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359624 1009 AEEALKAAQKKnDELETQAEELKKQAEQAKSL---SSVLASARKEIE 1052
Cdd:COG4717    465 LEEDGELAELL-QELEELKAELRELAEEWAALklaLELLEEAREEYR 510
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 576-1036 6.53e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.96  E-value: 6.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  576 ELWKSKleSAIASHQQAMEELkvsfnkgvgaqTAEFAELKTQMEKVKLDYENEMSNLKLKQE----NEKSQHLKE-IEAL 650
Cdd:COG3096    293 ELFGAR--RQLAEEQYRLVEM-----------ARELEELSARESDLEQDYQAASDHLNLVQTalrqQEKIERYQEdLEEL 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  651 KAKLlevtEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASE 725
Cdd:COG3096    360 TERL----EEQEEVVEEAAEQLAEAEAR-----------LEAAEEEVDSLksqlaDYQQALDVQQTRAI-QYQQAVQALE 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  726 E--KLLDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDS 803
Cdd:COG3096    424 KarALCGLPDLTPENAEDYLA------AFRAKEQQA------------------------TEEVLELEQKLSVADAARRQ 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  804 LEKELQLLkEKFTSAVDGAENAQRAmQETINKLnqkeeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEn 883
Cdd:COG3096    474 FEKAYELV-CKIAGEVERSQAWQTA-RELLRRY-----------RSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLE- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  884 diaEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQL 963
Cdd:COG3096    540 ---EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE-----LAARAPAWLAAQDAL 611

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359624  964 TDMKKQmetSQNQYKDLQakyeketsemitkhdaDIKGFKQNLLDAEEALKAAQkknDELETQAEELKKQAEQ 1036
Cdd:COG3096    612 ERLREQ---SGEALADSQ----------------EVTAAMQQLLEREREATVER---DELAARKQALESQIER 662
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1446-2020 7.00e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 7.00e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1446 RKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDAR 1525
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAE-----LEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1526 RTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNn 1605
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE- 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1606 igfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSC 1685
Cdd:COG1196    370 ---AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1686 VSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLvIINEEILKEKEKLSKEYYKLHE------KVVALLEQTDADFSC 1759
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAEL-LEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGA 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1760 RLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1839
Cdd:COG1196    526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1840 KLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLA-ALQEENVKLAEELGRSRDEVTSH 1918
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSlTGGSRRELLAALLEAEAELEELA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1919 QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTL 1998
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765

                          570       580
                   ....*....|....*....|..
gi 2024359624 1999 QSVVKtlesdklKLEEKVKNLE 2020
Cdd:COG1196    766 ERELE-------RLEREIEALG 780
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 732-1471 7.47e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 7.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  732 AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQkllDLEKNLSAVNQVKDSLEKELQLL 811
Cdd:TIGR00618  155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  812 KEkftsavdgaenAQRAMQETINKLNQKEEQFALMSS---ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEI 888
Cdd:TIGR00618  232 RE-----------ALQQTQQSHAYLTQKREAQEEQLKkqqLLKQLRARIEELRAQEAVLEETQERINRARKAAP--LAAH 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  889 MKSSGDSSAQLMKMNDELRLKERQLEQI--QLELTKANEKAVQLQKNVEQTAQKAEQ------SQQETLKTHQEELKKMQ 960
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLlmKRAAHVKQQSSIEEQRRLLQTLHSQEIhirdahEVATSIREISCQQHTLT 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  961 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK--HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK 1038
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1039 SLSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKESLLSQHLEMESkiLLVQQDREELWTKNEELNSENKKIL 1118
Cdd:TIGR00618  459 IHLQESAQSLKERE-------QQLQTKEQIHLQETRKKAVVLARLLELQEEPC--PLCGSCIHPNPARQDIDNPGPLTRR 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1119 KQKEAAEAKSRQESTEKV-----ALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK 1193
Cdd:TIGR00618  530 MQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1194 HIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvSILTAERDSAQEKDLDLKSTHIALKneidc 1273
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLASRQLALQ----- 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1274 llqtnrSLQSEKEMLLKSREELcvslantaneNQALKLRKDEMQTELETEREkLEKMTKDNMDLKASLSSLSNFLEEMKS 1353
Cdd:TIGR00618  684 ------KMQSEKEQLTYWKEML----------AQCQTLLRELETHIEEYDRE-FNEIENASSSLGSDLAAREDALNQSLK 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1354 SREASNSEKIHLLQEALFASEQRLL------AEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS 1427
Cdd:TIGR00618  747 ELMHQARTVLKARTEAHFNNNEEVTaalqtgAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL 826

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359624 1428 LQFEKHNEALLREKD----ELERKYSELLDEKKSLENAFSDMKREQEL 1471
Cdd:TIGR00618  827 VQEEEQFLSRLEEKSatlgEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
657-1232 7.91e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 7.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  657 VTEEKEQTLENLKAKLESVEDQHLVEmedtlnKLQEAEIKVKELDVLQAKCNEQTkligsltqqiRASEEKLLDLAALQK 736
Cdd:PRK02224   181 VLSDQRGSLDQLKAQIEEKEEKDLHE------RLNGLESELAELDEEIERYEEQR----------EQARETRDEADEVLE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  737 ANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT 816
Cdd:PRK02224   245 EHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  817 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 896
Cdd:PRK02224   325 ELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  897 AQLMKMND----------ELRLKERQLEQIQLELTKANEKAVQLQK--NVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQL 963
Cdd:PRK02224   405 VDLGNAEDfleelreerdELREREAELEATLRTARERVEEAEALLEagKCPECGQPVEGSPHvETIEEDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  964 TDMKKQMETSQNQYKdlQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslsSV 1043
Cdd:PRK02224   485 EDLEEEVEEVEERLE--RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR---EA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1044 LASARKEIELMSDKMRDLISEKETLAQERNTLKlEKESLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEa 1123
Cdd:PRK02224   560 AAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREAL----AELNDERRERLAEKR- 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1124 aEAKSRQESTEKVALISEkskLLSEIETAQADLLKITQENDALRSSESTLLQQLKelqankdavdvACQKHIKEREELEH 1203
Cdd:PRK02224   634 -ERKRELEAEFDEARIEE---AREDKERAEEYLEQVEEKLDELREERDDLQAEIG-----------AVENELEELEELRE 698

                          570       580
                   ....*....|....*....|....*....
gi 2024359624 1204 YQKLLEENDRVIKDKDDVIQRLQSSYDDL 1232
Cdd:PRK02224   699 RREALENRVEALEALYDEAEELESMYGDL 727
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 751-951 1.04e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 53.30  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  751 QLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQ 830
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  831 ETINKLNQKEeqFALMSSELEQLKSNLTVMET-------KLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 903
Cdd:COG3883     97 RSGGSVSYLD--VLLGSESFSDFLDRLSALSKiadadadLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359624  904 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 951
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1485-2007 1.11e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1485 TLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLEnelaavshakqVLSSSFNTCSSDIEILNRERTELQ 1564
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-----------TLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1565 DKCQKLTGEVENMKENLT---VEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKL 1641
Cdd:PRK02224   279 EEVRDLRERLEELEEERDdllAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1642 EEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSL 1721
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1722 viinEEILKEKEKLskeyykLHEKVVALLEQT--DADFSCRLLVSEGKHELLLEEMSNLALKLREIE-RLQAQTFMQKFE 1798
Cdd:PRK02224   439 ----RERVEEAEAL------LEAGKCPECGQPveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEeRLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1799 AD-KRAEEVLQTMEKVTKEKDAIHQEKIETLASLensRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1877
Cdd:PRK02224   509 DRiERLEERREDLEELIAERRETIEEKRERAEEL---RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELK 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1878 KEFEALK------LAAAQKSQQLAALQEENVKLAEELGRSRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRES 1947
Cdd:PRK02224   586 ERIESLErirtllAAIADAEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQV 665

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1948 TLK-KEIDEERASLQKSIsdtsALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLES 2007
Cdd:PRK02224   666 EEKlDELREERDDLQAEI----GAVENELEELEELRERREALENRVEALEALYDEAEELES 722
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1490-2040 1.26e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1490 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSH---AKQVLSSSFNTCSSDIEILNRERTELQDK 1566
Cdd:TIGR04523  147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkllKLELLLSNLKKKIQKNKSLESQISELKKQ 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1567 CQKLTGEVENMKENLtVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEkekSETKLEEVIK 1646
Cdd:TIGR04523  227 NNQLKDNIEKKQQEI-NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQ---LKSEISDLNN 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1647 EKMilyketeqlASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINE 1726
Cdd:TIGR04523  303 QKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1727 EILKEKEKLSKEYYKLHEKVVALLEQtdadFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEE- 1805
Cdd:TIGR04523  374 KLKKENQSYKQEIKNLESQINDLESK----IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQd 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1806 -VLQTMEKVTKEKDAIHQEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEAL 1883
Cdd:TIGR04523  450 sVKELIIKNLDNTRESLETQLKVLsRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1884 KLAAAQKSQQLAALQEENVKLAEELGRSrdevtshqKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEerasLQKS 1963
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKKE--------NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ----KEKE 597

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1964 ISDTSALITQKDEELEKLRNEITVLRGENasaktlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDI 2040
Cdd:TIGR04523  598 KKDLIKEIEEKEKKISSLEKELEKAKKEN----------EKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEI 664
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
615-1113 1.31e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  615 KTQMEKVKLDYENEMSNLKLKQENEKSQHLKE-IEALKAKLLEVTEEKE----------QTLENLKAKLESVED--QHLV 681
Cdd:PRK02224   175 RLGVERVLSDQRGSLDQLKAQIEEKEEKDLHErLNGLESELAELDEEIEryeeqreqarETRDEADEVLEEHEErrEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  682 EMEDTLNKLQEA-EIKVKELDVLQAKCNEQTKLIGSLTQQI----------RASEEKLLD-LAALQKANSEGKLEIQKLS 749
Cdd:PRK02224   255 TLEAEIEDLRETiAETEREREELAEEVRDLRERLEELEEERddllaeagldDADAEAVEArREELEDRDEELRDRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  750 EQLQAAEKQIQN-------LETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAvnqvkdsLEKELQLLKEKFTSAVDGA 822
Cdd:PRK02224   335 VAAQAHNEEAESlredaddLEERAEELREEAAELESELEEAREAVEDRREEIEE-------LEEEIEELRERFGDAPVDL 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  823 ENAqramqetinklnqkEEQFALMSSELEQLKSNLTVMETKLKEREER----EQQLTEAKV-KLENDI--AEIMKSSGDS 895
Cdd:PRK02224   408 GNA--------------EDFLEELREERDELREREAELEATLRTARERveeaEALLEAGKCpECGQPVegSPHVETIEED 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  896 SAQLMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQSqQETLKTHQEELKKMQDQLTDMKKQMEtsqn 975
Cdd:PRK02224   474 RERVEELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDL-EELIAERRETIEEKRERAEELRERAA---- 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  976 qykDLQAKYEKETSEMITKHDAdikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSvLASARKEIELMS 1055
Cdd:PRK02224   548 ---ELEAEAEEKREAAAEAEEE-----------AEEAREEVAELNSKLAELKERIESLERIRTLLAA-IADAEDEIERLR 612

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624 1056 DKmRDLISEKETLAQERNTLKLEKESLLSQHLEmESKILLVQQDREELWTKNEELNSE 1113
Cdd:PRK02224   613 EK-REALAELNDERRERLAEKRERKRELEAEFD-EARIEEAREDKERAEEYLEQVEEK 668
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
956-1506 1.53e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  956 LKKMQDQLTDMKKQMEtsQNQYKDLQAK---YEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1032
Cdd:PRK02224   182 LSDQRGSLDQLKAQIE--EKEEKDLHERlngLESELAEL----DEEIERYEEQREQARETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1033 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL-------KLEKESLLSQHLEMESKILLVQQDREELWT 1105
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1106 KNEELNSENKKILkqKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQADLLKITQENDALRSsestllqqlkELQANKD 1185
Cdd:PRK02224   336 AAQAHNEEAESLR--EDADDLEERAEELR-----EEAAELESELEEAREAVEDRREEIEELEE----------EIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1186 AVDVACQkhikEREELEHYQKLLEEN-DRVIKDKDDVIQRLQSSYDDLARNQR--------ELLQEVS----ILTAERDS 1252
Cdd:PRK02224   399 RFGDAPV----DLGNAEDFLEELREErDELREREAELEATLRTARERVEEAEAlleagkcpECGQPVEgsphVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1253 AQEKDL-----DLKSTHIALKNEIDcLLQTNRSLQSEKEMLLKSRE---ELCVSLANTANEN----QALKLRKDEMQTEL 1320
Cdd:PRK02224   475 ERVEELeaeleDLEEEVEEVEERLE-RAEDLVEAEDRIERLEERREdleELIAERRETIEEKreraEELRERAAELEAEA 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1321 ETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNS-EKIHLLQEALFASEQRLLAEREELVNENKAVTEKL-TKA 1398
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREKREALAELNDERRERLaEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1399 TADAVLAETAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-EQELDFSAKR 1477
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAREDKE-------RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElRERREALENR 706

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2024359624 1478 L-----LVQENTTLKYSIEALEEELKKKNLENQE 1506
Cdd:PRK02224   707 VealeaLYDEAEELESMYGDLRAELRQRNVETLE 740
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 691-1213 3.45e-06

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 52.45  E-value: 3.45e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  691 QEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 770
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  771 SKVSNLTKELQGKEQKLLdlEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 850
Cdd:pfam07111  143 EEIQRLHQEQLSSLTQAH--EEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  851 EQLKSNL---TVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL-------------- 913
Cdd:pfam07111  221 ESLRKYVgeqVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELtrkiqpsdslepef 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  914 -EQIQLELTKANEKAVQLQknVEQTAQKAEQSqqETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 991
Cdd:pfam07111  301 pKKCRSLLNRWREKVFALM--VQLKAQDLEHR--DSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAk 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  992 -----ITKHDADIKGFKQNLLDAEEALK----AAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdKMRDLI 1062
Cdd:pfam07111  377 glqmeLSRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVH----TIKGLM 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1063 SEKETLAQerntLKLEKESLLSQHLEMESKILL-VQQDREELWTKNEELNSENKKIlkQKEAAEAKSRQEStEKVALISE 1141
Cdd:pfam07111  453 ARKVALAQ----LRQESCPPPPPAPPVDADLSLeLEQLREERNRLDAELQLSAHLI--QQEVGRAREQGEA-ERQQLSEV 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1142 KSKLLSEIETAQADLLKITQENDALRSSESTLLQQL----KELQANKDAVDVACQKHIKE-----REELEHYQKLLEEND 1212
Cdd:pfam07111  526 AQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAaslrQELTQQQEIYGQALQEKVAEvetrlREQLSDTKRRLNEAR 605


                   .
gi 2024359624 1213 R 1213
Cdd:pfam07111  606 R 606
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1350-2029 3.51e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 3.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1350 EMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS-- 1427
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkk 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1428 -------------LQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE----QELDFSAKRLLVQENTTLKYSI 1490
Cdd:TIGR00618  259 qqllkqlrarieeLRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIhtelQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1491 EALEEELKKKNLENQE-LIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRErtelQDKCQK 1569
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEiHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1570 LTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK---EKSETKLEEVIK 1646
Cdd:TIGR00618  415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1647 EKMILYKETEQLASKIEQLKSDFTSLSVSKA------ELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKS 1720
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1721 LVIINEEILKEKEKLSKEyyklhekVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEAD 1800
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNI-------TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1801 KRAEEVLQTMEKVTKEKDAIHQEKIETLASlensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEF 1880
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLAS-------RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1881 EALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKeidEERASL 1960
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN---RLREED 797

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1961 QKSISDTSALITQK--DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 2029
Cdd:TIGR00618  798 THLLKTLEAEIGQEipSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQ 868
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 569-1952 4.64e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.36  E-value: 4.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  569 KENSDVIELWKSKLESAIASHQQAMEELKVSFN----KGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENEKSQHL 644
Cdd:TIGR01612  503 KDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKaklyKEIEAGLKESYELAKNWKKLIHEI-----KKELEEENEDSIHL 577

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  645 -KEIEALKAKLLEVTEE----KEQTLEnLKAKLESVED--QHLVEMEDTLNKLQEAEIKVKELDVLQA-KCNEQTKLIGS 716
Cdd:TIGR01612  578 eKEIKDLFDKYLEIDDEiiyiNKLKLE-LKEKIKNISDknEYIKKAIDLKKIIENNNAYIDELAKISPyQVPEHLKNKDK 656

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  717 LTQQIRASEEKLL--DLAALQKA-----------NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGgsskvSNLTKeLQGK 783
Cdd:TIGR01612  657 IYSTIKSELSKIYedDIDALYNElssivkenaidNTEDKAKLDDLKSKIDKEYDKIQNMETATVE-----LHLSN-IENK 730

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  784 EQKLLDLEKNLSavNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNL------ 857
Cdd:TIGR01612  731 KNELLDIIVEIK--KHIHGEINKDLNKILEDF-------KNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYndqini 801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  858 -TVMETKLKEREEREQQLTEAKVKLENDIAEIMKssgdssaQLMKMNDELrlkerqleqiqleLTKANeKAVQLQKNVEQ 936
Cdd:TIGR01612  802 dNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIIN-------EMKFMKDDF-------------LNKVD-KFINFENNCKE 860

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  937 TAQKAEQSQQETLKTHQEELKkmQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADikGFKQNLLDAEEALKAA 1016
Cdd:TIGR01612  861 KIDSEHEQFAELTNKIKAEIS--DDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVD--EYIKICENTKESIEKF 936

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1017 QKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIElmsdkmrdlisekETLAQERNTL-KLEKESLLSQHLEMESKILL 1095
Cdd:TIGR01612  937 HNKQNILK---EILNKNIDTIKESNLIEKSYKDKFD-------------NTLIDKINELdKAFKDASLNDYEAKNNELIK 1000

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1096 VQQDREELWTKNEElnsenkKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETA-QADLLKITQENDAL--RSSEST 1172
Cdd:TIGR01612 1001 YFNDLKANLGKNKE------NMLYHQFDEKEKATNDIEQK---IEDANKNIPNIEIAiHTSIYNIIDEIEKEigKNIELL 1071

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1173 LLQQLKELQANkdavdVACQKHIKEREELEHYQKLLEENDrvIKDKDDViqrlQSSYDDLARNQRELLQEVSILTAERDS 1252
Cdd:TIGR01612 1072 NKEILEEAEIN-----ITNFNEIKEKLKHYNFDDFGKEEN--IKYADEI----NKIKDDIKNLDQKIDHHIKALEEIKKK 1140

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1253 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMllksrEELCVSLANTANENQALKLRKDEMqTELETEREKLEKMTK 1332
Cdd:TIGR01612 1141 SENYIDEIKAQINDLEDVADKAISNDDPEEIEKKI-----ENIVTKIDKKKNIYDEIKKLLNEI-AEIEKDKTSLEEVKG 1214

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1333 DNMDLKASLSSLsnFLEEMKSSREASnsekihllqEALFASEQRLLAEREELvnenkavtEKLTKATADAVLAETAFTEK 1412
Cdd:TIGR01612 1215 INLSYGKNLGKL--FLEKIDEEKKKS---------EHMIKAMEAYIEDLDEI--------KEKSPEIENEMGIEMDIKAE 1275

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1413 INELNLEKESVFSKSLQFEKHNEAL--LREKD----ELERKYSELLDEKKSLENAFSDMKREQeldfSAKRLLVQENTTL 1486
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENIsdIREKSlkiiEDFSEESDINDIKKELQKNLLDAQKHN----SDINLYLNEIANI 1351

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1487 kYSIEALEeelKKKNLENQeliacrsdLSDLLKEAQDARRTLENELAAVSHAKQVL--SSSFNTCSSDIEilnrerTELQ 1564
Cdd:TIGR01612 1352 -YNILKLN---KIKKIIDE--------VKEYTKEIEENNKNIKDELDKSEKLIKKIkdDINLEECKSKIE------STLD 1413

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1565 DKcqKLTGEVENMKENltvekKARILDKES----FLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE------------ 1628
Cdd:TIGR01612 1414 DK--DIDECIKKIKEL-----KNHILSEESnidtYFKNADENNENVLLLFKNIEMADNKSQHILKIKKdnatndhdfnin 1486

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1629 LLVQEKEKSETKLEEVIKEKmilyKETEQLASKIEQLKSDFTSLSVSKAELedvhscvsvmldELQHKYEVTEKEKMELV 1708
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNA----KAIEKNKELFEQYKKDVTELLNKYSAL------------AIKNKFAKTKKDSEIII 1550

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1709 QENESLHaewKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLleEMSNLALK----LRE 1784
Cdd:TIGR01612 1551 KEIKDAH---KKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFL--KISDIKKKindcLKE 1625

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1785 IERLQAQ-------TFMQKFEADKRAEEVLQT-MEKVTKEKDAIHQEKIEtlasLENSRQTNEKLQNELDMLKQN----- 1851
Cdd:TIGR01612 1626 TESIEKKissfsidSQDTELKENGDNLNSLQEfLESLKDQKKNIEDKKKE----LDELDSEIEKIEIDVDQHKKNyeigi 1701

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1852 -------NLKNEEELTKSKELLnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEE 1924
Cdd:TIGR01612 1702 iekikeiAIANKEEIESIKELI---EPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSK 1778

                         1450      1460
                   ....*....|....*....|....*...
gi 2024359624 1925 RSVLNNQLLEMKKSLPSNTLRESTLKKE 1952
Cdd:TIGR01612 1779 EPITYDEIKNTRINAQNEFLKIIEIEKK 1806
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 354-1416 5.14e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.98  E-value: 5.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV-GEIEQELALVRDGhdrhvlEMEAKMDQLRAMVEAADREKVEllnql 432
Cdd:TIGR01612  625 LKKIIENNNAYIDELAKISPYQVPEHLKNKDKIySTIKSELSKIYED------DIDALYNELSSIVKENAIDNTE----- 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  433 eeEKRKVEDLQFRVEEESITKGDLEVATV--------SEKSRIM------------ELERDLALRVKEVAELRGRLES-- 490
Cdd:TIGR01612  694 --DKAKLDDLKSKIDKEYDKIQNMETATVelhlsnieNKKNELLdiiveikkhihgEINKDLNKILEDFKNKEKELSNki 771

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  491 ---SKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMsslKEKFESSEEALR----KEIKTLSASNERMGKENESLKTK 563
Cdd:TIGR01612  772 ndyAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDA---KQNYDKSKEYIKtisiKEDEIFKIINEMKFMKDDFLNKV 848

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  564 LDHANKENSDvielwKSKLESAIASHQQAMEELKVSF-NKGVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEks 641
Cdd:TIGR01612  849 DKFINFENNC-----KEKIDSEHEQFAELTNKIKAEIsDDKLNDYEKKFNDSKSLINEINKSIEEEYQNINtLKKVDE-- 921

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  642 qHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVE------MEDTL-NKLQEAEIKVKELDV--LQAKCNEQTK 712
Cdd:TIGR01612  922 -YIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEksykdkFDNTLiDKINELDKAFKDASLndYEAKNNELIK 1000

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  713 LIGSLTQQIRASEEKLldlaaLQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLD--- 789
Cdd:TIGR01612 1001 YFNDLKANLGKNKENM-----LYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNkei 1075

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  790 ---LEKNLSAVNQVKDSLE--KELQLLKE---KFTSAV----DGAENAQRAMQETINKL----NQKEEQFALMSSELEQL 853
Cdd:TIGR01612 1076 leeAEINITNFNEIKEKLKhyNFDDFGKEeniKYADEInkikDDIKNLDQKIDHHIKALeeikKKSENYIDEIKAQINDL 1155

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  854 K--SNLTVMETKLKEREEREQQLT----------EAKVKLENDIAEIMKSSGD-SSAQLMKMNDELRLKERQLEQIQLEL 920
Cdd:TIGR01612 1156 EdvADKAISNDDPEEIEKKIENIVtkidkkkniyDEIKKLLNEIAEIEKDKTSlEEVKGINLSYGKNLGKLFLEKIDEEK 1235

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  921 TKANEKAVQLQKNVEQTAQKAEQSQqetlkthqeELKKMQDQLTDMKKQMET---SQNQYKD---LQAKYEKETSEMITK 994
Cdd:TIGR01612 1236 KKSEHMIKAMEAYIEDLDEIKEKSP---------EIENEMGIEMDIKAEMETfniSHDDDKDhhiISKKHDENISDIREK 1306

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  995 HDADIKGF--KQNLLDAEEALKA----AQKKNDELETQAEELKK-----QAEQAKSLSSVLASARKEIELMSDKMRDLIS 1063
Cdd:TIGR01612 1307 SLKIIEDFseESDINDIKKELQKnlldAQKHNSDINLYLNEIANiynilKLNKIKKIIDEVKEYTKEIEENNKNIKDELD 1386

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1064 EKETLAQerntlKLEKESLLSqhlEMESKI--LLVQQDREELWTKNEELNSEnkkILKQKEAAEA--KSRQESTEKVALi 1139
Cdd:TIGR01612 1387 KSEKLIK-----KIKDDINLE---ECKSKIesTLDDKDIDECIKKIKELKNH---ILSEESNIDTyfKNADENNENVLL- 1454

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1140 sekskLLSEIETAQAD---LLKITQENdalrsSESTLLQQLKELQANKDavdvacqKHIKEREELEHYQKLLEENDRVIK 1216
Cdd:TIGR01612 1455 -----LFKNIEMADNKsqhILKIKKDN-----ATNDHDFNINELKEHID-------KSKGCKDEADKNAKAIEKNKELFE 1517

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1217 D-KDDVIQRLQSSYDDLARNQrellqevsILTAERDSAQEKDlDLKSthiaLKNEIdcLLQTNRSLQSEKEMllkSREEL 1295
Cdd:TIGR01612 1518 QyKKDVTELLNKYSALAIKNK--------FAKTKKDSEIIIK-EIKD----AHKKF--ILEAEKSEQKIKEI---KKEKF 1579

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1296 CVSlANTANENQALKLRKDeMQTELETEREKLEKMT----------KDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL 1365
Cdd:TIGR01612 1580 RIE-DDAAKNDKSNKAAID-IQLSLENFENKFLKISdikkkindclKETESIEKKISSFSIDSQDTELKENGDNLNSLQE 1657

                         1130      1140      1150      1160      1170
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1366 LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINEL 1416
Cdd:TIGR01612 1658 FLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEI 1708
COG5022 COG5022
Myosin heavy chain [General function prediction only];
624-1384 5.86e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 52.00  E-value: 5.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  624 DYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKA----KLESVEDQHLVEMEDTLNKLQEAEIKVKE 699
Cdd:COG5022    814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRfsllKKETIYLQSAQRVELAERQLQELKIDVKS 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  700 LDVLQAKCNEQTKLIGSLTQQIRASeeklldlaalqkansegkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK- 778
Cdd:COG5022    894 ISSLKLVNLELESEIIELKKSLSSD-----------------------LIENLEFKTELIARLKKLLNNIDLEEGPSIEy 950

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  779 ELQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkekftsavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLT 858
Cdd:COG5022    951 VKLPELNKLHEVESKLKETSEEYEDLLKK---------------------STILVREGNKANSELKNFKKELAELSKQYG 1009

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  859 VMETKLKEREEREQQLTEakvkLENDIAeIMKSSGDSSAQLMKMNDELRLKERQLEQiqlelTKANEKAVQLQknveqta 938
Cdd:COG5022   1010 ALQESTKQLKELPVEVAE----LQSASK-IISSESTELSILKPLQKLKGLLLLENNQ-----LQARYKALKLR------- 1072

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  939 qkaeqsqqetlkthqeelKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemitkhdaDIKGFKQNLLDAEEAL---KA 1015
Cdd:COG5022   1073 ------------------RENSLLDDKQLYQLESTENLLKTINVK--------------DLEVTNRNLVKPANVLqfiVA 1120

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 AQKKNDELetqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILL 1095
Cdd:COG5022   1121 QMIKLNLL----QEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSS 1196

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1096 VQQdrEELWTKNEELNSENKKILKQkeaaeAKSRQESTEKVALISEKSKLLSEIEtaQADLLKITQENdalRSSEStLLQ 1175
Cdd:COG5022   1197 SEV--NDLKNELIALFSKIFSGWPR-----GDKLKKLISEGWVPTEYSTSLKGFN--NLNKKFDTPAS---MSNEK-LLS 1263

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1176 QLKELQankdavDVACQKHIKEREELEHYQKLLEENDrvikdkddviqrlQSSYDDLARNQRELLQEVSiLTAERDSAQE 1255
Cdd:COG5022   1264 LLNSID------NLLSSYKLEEEVLPATINSLLQYIN-------------VGLFNALRTKASSLRWKSA-TEVNYNSEEL 1323

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1256 KDLDLKSTHIALKNEIDCLLQTNRSLQSEKEML--LKSREELCVSLANTanENQALKLRKDEMQTELETEREKLEKMTKD 1333
Cdd:COG5022   1324 DDWCREFEISDVDEELEELIQAVKVLQLLKDDLnkLDELLDACYSLNPA--EIQNLKSRYDPADKENNLPKEILKKIEAL 1401

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1334 NMDLKASLSSLSnFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL 1384
Cdd:COG5022   1402 LIKQELQLSLEG-KDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSLSAL 1451
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1647-2036 7.30e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 51.28  E-value: 7.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1647 EKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhSCVSVMLDELQHKYEVTEKEKMELVQ--ENESLHAEwkslvii 1724
Cdd:pfam17380  234 EKMERRKESFNLAEDVTTMTPEYTVRYNGQTMTEN--EFLNQLLHIVQHQKAVSERQQQEKFEkmEQERLRQE------- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1725 NEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELlleEMSNLALKLREIERLQAQTFMQKFEADKRAE 1804
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMEREREL---ERIRQEERKRELERIRQEEIAMEISRMRELE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1805 ----EVLQTMEKVTKEKDAIHQEKIetlasLENSRQTNEKLQneldMLKQNNLKNEEELTKSKELLNLEnkkvEELKKEF 1880
Cdd:pfam17380  382 rlqmERQQKNERVRQELEAARKVKI-----LEEERQRKIQQQ----KVEMEQIRAEQEEARQREVRRLE----EERAREM 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1881 EALKLAAAQKSQQLAAL-QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERAS 1959
Cdd:pfam17380  449 ERVRLEEQERQQQVERLrQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKA 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1960 L----QKSISDTSALITQKDEELEKLRNEITVLRGEnasaktlQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTS 2035
Cdd:pfam17380  529 IyeeeRRREAEEERRKQQEMEERRRIQEQMRKATEE-------RSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   .
gi 2024359624 2036 P 2036
Cdd:pfam17380  602 P 602
mukB PRK04863
chromosome partition protein MukB;
576-1328 9.33e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.11  E-value: 9.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  576 ELWKSKleSAIASHQQAMEELKvsfnkgvgaqtAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhlKEIEALKAKLL 655
Cdd:PRK04863   294 ELYTSR--RQLAAEQYRLVEMA-----------RELAELNEAESDLEQDYQAASDHLNLVQTALRQQ--EKIERYQADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  656 EVTEEkeqtlenLKAKLESVEDQHLvEMEDTLNKLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASEE--KL 728
Cdd:PRK04863   359 ELEER-------LEEQNEVVEEADE-QQEENEARAEAAEEEVDELksqlaDYQQALDVQQTRAI-QYQQAVQALERakQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  729 LDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDSLEKEL 808
Cdd:PRK04863   430 CGLPDLTADNAEDWLE------EFQAKEQEA------------------------TEELLSLEQKLSVAQAAHSQFEQAY 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  809 QLLKekftsAVDGAENAQRAMQETINKLNQKEEQFALmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL---ENDI 885
Cdd:PRK04863   480 QLVR-----KIAGEVSRSEAWDVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLgknLDDE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  886 AEIMKSSGDSSAQLMKMNDELR-LKER------QLEQIQLELTK----------ANEKAVQLQknvEQTAQKAEQSQQ-- 946
Cdd:PRK04863   554 DELEQLQEELEARLESLSESVSeARERrmalrqQLEQLQARIQRlaarapawlaAQDALARLR---EQSGEEFEDSQDvt 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  947 ETLKTHQEELKKMQ---DQLTDMKKQMEtsqNQYKDLQAKYEKETSEM------------------ITKHDA-------- 997
Cdd:PRK04863   631 EYMQQLLERERELTverDELAARKQALD---EEIERLSQPGGSEDPRLnalaerfggvllseiyddVSLEDApyfsalyg 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  998 ---------------------------------DIKGFKQNLLDAEEALKA-AQKKND-EL----------------ETQ 1026
Cdd:PRK04863   708 parhaivvpdlsdaaeqlagledcpedlyliegDPDSFDDSVFSVEELEKAvVVKIADrQWrysrfpevplfgraarEKR 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1027 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLA---------QERNTLKLEKESLLSQHlemESKIllvQ 1097
Cdd:PRK04863   788 IEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeaelRQLNRRRVELERALADH---ESQE---Q 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1098 QDREELWTKNEELNSENK-----KILK----QKEAAEAKSRQESTEKVAL-ISEKSKLLSEIETAQADLLKITQENDALR 1167
Cdd:PRK04863   862 QQRSQLEQAKEGLSALNRllprlNLLAdetlADRVEEIREQLDEAEEAKRfVQQHGNALAQLEPIVSVLQSDPEQFEQLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1168 SSESTLLQQLKELQANKDAVD--VACQKH-----------------IKEREELEHYQKLLEENDRVIKDKDD-------V 1221
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTevVQRRAHfsyedaaemlaknsdlnEKLRQRLEQAEQERTRAREQLRQAQAqlaqynqV 1021

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1222 IQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthialKNEIDCLLQTNRSLQSEKEMLLKSREElcvslan 1301
Cdd:PRK04863  1022 LASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR------RDELHARLSANRSRRNQLEKQLTFCEA------- 1088

                          890       900
                   ....*....|....*....|....*..
gi 2024359624 1302 tANENQALKLRKdeMQTELETEREKLE 1328
Cdd:PRK04863  1089 -EMDNLTKKLRK--LERDYHEMREQVV 1112
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1033-1256 9.89e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 9.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1033 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNS 1112
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1113 ---ENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEN-DALRSSESTLLQQLKELQANKDAVD 1188
Cdd:COG4942     98 eleAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624 1189 VACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEK 1256
Cdd:COG4942    178 ALLAELEEERAALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
353-982 1.16e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE--------ELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  433 EEEKRKVEDLQFRVEE--ESITKGDLEVATVSEK-----SRIMELERDLALRVKEVAELRGRLES-SKHIDDVDTslsll 504
Cdd:PRK02224   282 RDLRERLEELEEERDDllAEAGLDDADAEAVEARreeleDRDEELRDRLEECRVAAQAHNEEAESlREDADDLEE----- 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  505 qEISSLQEKMAAAGKEHQREMSSLkEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSkLES 584
Cdd:PRK02224   357 -RAEELREEAAELESELEEAREAV-EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAE-LEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  585 AIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkldyenemsnlklkQENEKSQHLKEIEALKAKLLEVTEEkeqt 664
Cdd:PRK02224   434 TLRTARERVEEAEALLEAGKCPECG--------------------------QPVEGSPHVETIEEDRERVEELEAE---- 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  665 LENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQQIRASeeklldlaalqkansegkle 744
Cdd:PRK02224   484 LEDLEEEVEEVEERL-----ERAEDLVEAEDRIERLE-------ERREDLEELIAERRET-------------------- 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  745 IQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsavdgAEN 824
Cdd:PRK02224   532 IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA--------IAD 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  825 AqramQETINKLNQKEEQFALMSSELEQlksnltvmetKLKEREEREQQLTEakvKLENDIAEIMKSSGDSSaqlmkmnd 904
Cdd:PRK02224   604 A----EDEIERLREKREALAELNDERRE----------RLAEKRERKRELEA---EFDEARIEEAREDKERA-------- 658

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624  905 elrlkERQLEQIQLELTKANEKAVQLQKNVeqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 982
Cdd:PRK02224   659 -----EEYLEQVEEKLDELREERDDLQAEI--GAVENELEELEELRERREALENRVEALEALYDEAEELESMYGDLRA 729
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1655-2004 1.25e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1655 TEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQH------KYEVTEKEKMELvqENESLHAEWKSLVIINEEI 1728
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeRYQALLKEKREY--EGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1729 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsegkHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA----- 1803
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEE------------IEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASlersi 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1804 EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKqnnlkneEELTKSKELLNLENKKVEELKKEFEAL 1883
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1884 KLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDE---ERASL 1960
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEEL---QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKqewKLEQL 460

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2024359624 1961 QKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2004
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 594-808 1.26e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 50.44  E-value: 1.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  594 EELKVSFNKgvgaqtaEFAELKTQMEKVKLDYENEMSNL--KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAK 671
Cdd:pfam13166  271 AALEAHFDD-------EFTEFQNRLQKLIEKVESAISSLlaQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGLRRA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  672 LESVEDQ--HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLdlaalqkaNSEGKLEIQKLS 749
Cdd:pfam13166  344 LEAKRKDpfKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAKKKLRLHL--------VEEFKSEIDEYK 415

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624  750 EQLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKEL 808
Cdd:pfam13166  416 DKYAGLEKAINSLEKEI-------KNLEAEIKKLREEIKELEAQLRDHKPGADEINKLL 467
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
658-878 1.36e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  658 TEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKELdvlqakcnEQTKLIGSLTQQIRASEEKLldlAALQKA 737
Cdd:COG3206    170 REEARKALEFLEEQLPELRKE-----------LEEAEAALEEF--------RQKNGLVDLSEEAKLLLQQL---SELESQ 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  738 NSEGKLEIQKLSEQLQAAEKQIQNLETE--KVGGSSKVSNLTKELQGKEQKLLDLEKNLSA-----------VNQVKDSL 804
Cdd:COG3206    228 LAEARAELAEAEARLAALRAQLGSGPDAlpELLQSPVIQQLRAQLAELEAELAELSARYTPnhpdvialraqIAALRAQL 307

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624  805 EKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAK 878
Cdd:COG3206    308 QQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
645-879 1.55e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 1.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  645 KEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhlVEMEDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRAS 724
Cdd:COG3206    182 EQLPELRKEL----EEAEAALEEFRQKNGLVDLS--EEAKLLLQQLSELE---SQLAEARAELAEAEARLAALRAQLGSG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  725 EEKLLDLAALQkansegklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLdleknlSAVNQVKDSL 804
Cdd:COG3206    253 PDALPELLQSP--------VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------QEAQRILASL 318

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624  805 EKELQLLKEKftsaVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE-REEREQQLTEAKV 879
Cdd:COG3206    319 EAELEALQAR----EASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEaRLAEALTVGNVRV 390
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 937-1182 1.69e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.44  E-value: 1.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  937 TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAA 1016
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE--------LEALQAEIDKLQAEIAEAEAEIEER 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1017 QkknDELETQAEELKKQAEQAKSLSSVLASA--------RKEIELMSDKMRDLISEketLAQERNTLKLEKESLlsqhle 1088
Cdd:COG3883     85 R---EELGERARALYRSGGSVSYLDVLLGSEsfsdfldrLSALSKIADADADLLEE---LKADKAELEAKKAEL------ 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1089 meskillvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1168
Cdd:COG3883    153 --------EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224

                          250
                   ....*....|....
gi 2024359624 1169 SESTLLQQLKELQA 1182
Cdd:COG3883    225 AAAAAAAAAAAAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 759-1446 1.82e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  759 IQNLETEKVGGSSKVSNLTKE--LQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKL 836
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLARQfaLCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  837 NQKEEQFALMSSELEQLKsnltvMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ- 915
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTK-----LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEk 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  916 ---IQLELTKANEKAVQLQKNVEQTAQKAEQSQQ---ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETS 989
Cdd:pfam12128  303 rdeLNGELSAADAAVAKDRSELEALEDQHGAFLDadiETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRS 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  990 EMITKHDADIKGFKQNLLDA-EEALKAAQKKNDELETQAEELKKQAEQAKSLSSV----LASARKEIELMSDKMRDLISE 1064
Cdd:pfam12128  383 KIKEQNNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEFNEeeyrLKSRLGELKLRLNQATATPEL 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1065 KETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS---- 1140
Cdd:pfam12128  463 LLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHflrk 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1141 -------EKSKLLSEIETAQADLlkITQENDALRSSESTLL------------------QQLK-ELQANKDAVDVACQKH 1194
Cdd:pfam12128  543 eapdweqSIGKVISPELLHRTDL--DPEVWDGSVGGELNLYgvkldlkridvpewaaseEELReRLDKAEEALQSAREKQ 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1195 IKEREELEHYQKLLEENDRvikDKDDVIQRLQSSYDDLAR----NQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNE 1270
Cdd:pfam12128  621 AAAEEQLVQANGELEKASR---EETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1271 IDCLLQTNR--SLQSEKEMLLKSRE---ELCVSLA----NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASL 1341
Cdd:pfam12128  698 HQAWLEEQKeqKREARTEKQAYWQVvegALDAQLAllkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1342 SSLSNFLEEMKSSREASNSEKIhLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafteKINELNLEKE 1421
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFD-WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADT---------KLRRAKLEME 847

                          730       740
                   ....*....|....*....|....*
gi 2024359624 1422 SVFSKSLQFEKhNEALLREKDELER 1446
Cdd:pfam12128  848 RKASEKQQVRL-SENLRGLRCEMSK 871
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1951-2081 2.16e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1951 KEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASaktlqsvvktLESDKLKLEEKVKNLEQKLK-AKSEQ 2029
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEE----------LEAELEEKDERIERLERELSeARSEE 457

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024359624 2030 PltvtspsgdiaANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2081
Cdd:COG2433    458 R-----------REIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1515-2029 2.65e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.33  E-value: 2.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1515 SDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKEN---LTVEKKARILD 1591
Cdd:pfam05483  281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAhsfVVTEFEATTCS 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1592 KESFL-LERMELQNNIGFLEKEVEEMREKNKEfLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1670
Cdd:pfam05483  361 LEELLrTEQQRLEKNEDQLKIITMELQKKSSE-LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1671 SLS----VSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQE---NESLHAEWKSLVIINEEILKEKEKLSKEYYKLH 1743
Cdd:pfam05483  440 ELIfllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEklkNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1744 EKVVALLEQTDAdfscrllvsegkhellleemsnlalKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDaihqe 1823
Cdd:pfam05483  520 EDIINCKKQEER-------------------------MLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLD----- 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1824 KIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnlENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1903
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN---------KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNK 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1904 LAEELGRSRDE----VTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEErasLQKSISDTSALITQKDEELE 1979
Cdd:pfam05483  641 LELELASAKQKfeeiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKR---CQHKIAEMVALMEKHKHQYD 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1980 KLRNEITVLRGENASAKTLQSVVK-TLESDKLKLEEKVKNLEQKLKAKSEQ 2029
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKaALEIELSNIKAELLSLKKQLEIEKEE 768
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 630-878 3.34e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  630 SNLKLKQENEKSQHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQeaeikvKELDVLQAKCNE 709
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERR-IAALARRIRALE------QELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  710 QTKLIGSLTQQIRASEEKLLD-LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggSSKVSNLTKELQGKEQKLL 788
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAElLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL----APARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  789 DLEKNLSAVNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 868
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAAL-------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                          250
                   ....*....|
gi 2024359624  869 EREQQLTEAK 878
Cdd:COG4942    237 AAAAERTPAA 246
PRK01156 PRK01156
chromosome segregation protein; Provisional
 462-1064 3.82e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.13  E-value: 3.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  462 SEKSRIMELERDLALRVKEVAELrgrlesSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQ------REMSSLKEKFES 534
Cdd:PRK01156   180 AEISNIDYLEEKLKSSNLELENI------KKQIADDEKSHSiTLKEIERLSIEYNNAMDDYNnlksalNELSSLEDMKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  535 SEEALRKEIKTLSASNERMGK----ENESLKTKLDHANKENSDVIELWKSKleSAIASHQQAMEELKVSFNK--GVGAQT 608
Cdd:PRK01156   254 YESEIKTAESDLSMELEKNNYykelEERHMKIINDPVYKNRNYINDYFKYK--NDIENKKQILSNIDAEINKyhAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  609 AEFAELKTQMEKVKLDYE---NEMSNLKLKQENEKSqHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQHLVEmed 685
Cdd:PRK01156   332 SVLQKDYNDYIKKKSRYDdlnNQILELEGYEMDYNS-YLKSIESLKKKI----EEYSKNIERMSAFISEILKIQEID--- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  686 tlnklqeAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA-LQKANSEGKLEIQKLSEQLQAAEKQIQNLET 764
Cdd:PRK01156   404 -------PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRnMEMLNGQSVCPVCGTTLGEEKSNHIINHYNE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  765 EKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK-DSLEKELQLLKEKFTSAVDgAENAQRAMQETINKLNQKEEQF 843
Cdd:PRK01156   477 KKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLED-IKIKINELKDKHDKYEEIKNRY 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  844 AlmSSELEQLKSNLTV------------METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKER 911
Cdd:PRK01156   556 K--SLKLEDLDSKRTSwlnalavislidIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  912 QLEQIQlELTKANEKavqLQKNVEQtaqkaeqsqqetLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM 991
Cdd:PRK01156   634 KYNEIQ-ENKILIEK---LRGKIDN------------YKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANR 697

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624  992 ITKhDADIKGFKQNLLDAEEALKAAQKKNDELET--QAEELKKQAEQAKSLSSVLASARKEI-ELMSDKMRDLISE 1064
Cdd:PRK01156   698 ARL-ESTIEILRTRINELSDRINDINETLESMKKikKAIGDLKRLREAFDKSGVPAMIRKSAsQAMTSLTRKYLFE 772
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1021-1593 3.92e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.13  E-value: 3.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1021 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1100
Cdd:PRK01156   176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYE 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1101 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVA---LISEKSKLLSEIEtaqaDLLKITQENDALRSSESTLLQQL 1177
Cdd:PRK01156   256 SEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKnrnYINDYFKYKNDIE----NKKQILSNIDAEINKYHAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1178 KELQANKDAVdvacQKHIKEREELEH-----------YQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL 1246
Cdd:PRK01156   332 SVLQKDYNDY----IKKKSRYDDLNNqilelegyemdYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1247 TAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLlkSREELCVSLANTANENQALKLRKD--EMQTELETER 1324
Cdd:PRK01156   408 KKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEML--NGQSVCPVCGTTLGEEKSNHIINHynEKKSRLEEKI 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1325 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAL--FASEQRLLAER----EELVNENKAVTEKLTKA 1398
Cdd:PRK01156   486 REIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLedIKIKINELKDKhdkyEEIKNRYKSLKLEDLDS 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1399 TADAVLAETAFTEKINELNLEKesvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELdFSAKRL 1478
Cdd:PRK01156   566 KRTSWLNALAVISLIDIETNRS--------RSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANN-LNNKYN 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1479 LVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILN- 1557
Cdd:PRK01156   637 EIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSd 716

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2024359624 1558 -----RERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1593
Cdd:PRK01156   717 rindiNETLESMKKIKKAIGDLKRLREAFDKSGVPAMIRKS 757
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 353-570 4.69e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 4.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  433 EEEKRKVEDL---QFRVEEESITKGDLEVATVSEKSRIMELERDLA-LRVKEVAELRGRLEsskhidDVDTSLSLLQEIS 508
Cdd:COG4942    100 EAQKEELAELlraLYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLApARREQAEELRADLA------ELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624  509 SLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 570
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
750-1052 4.81e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  750 EQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLlkekftsavdgaenaqRAM 829
Cdd:COG4913    610 AKLAALEAELAELEEE-------LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV----------------ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  830 QETINKLNQKEEQFALMSSELEQLKSnltvmetKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlk 909
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEE-------QLEELEAELEELEEELDELKGEIGRL--------------------- 718

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  910 ERQLEQIQLELTkanekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKmQDQLTDMKKQMETSQNQYKDLQAKYEKETS 989
Cdd:COG4913    719 EKELEQAEEELD-------ELQDRLEAAEDLARLELRALLEERFAAALG-DAVERELRENLEERIDALRARLNRAEEELE 790

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359624  990 EMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQ---------AEELKKQAEQAKS-LSSVLASARKEIE 1052
Cdd:COG4913    791 RAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDglpeyeerfKELLNENSIEFVAdLLSKLRRAIREIK 863
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
660-1255 5.02e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 5.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  660 EKEQTLENLKAKLESVEDqhLVEMEDTLNKLQEaeiKVKELDVLQAKCNEQTKLIGSLTQQIRasEEKLLDLAALQKANS 739
Cdd:COG4913    219 EEPDTFEAADALVEHFDD--LERAHEALEDARE---QIELLEPIRELAERYAAARERLAELEY--LRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  740 EGKLEIQKLSEQLQAAEKQIQNLETEKVG---------------GSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSL 804
Cdd:COG4913    292 LLEAELEELRAELARLEAELERLEARLDAlreeldeleaqirgnGGDRLEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  805 -------EKELQLLKEKFTSAVDGAENAQRAMQ----ETINKLNQKEEQFALMSSELEQL---KSNLTVMETKLKEREER 870
Cdd:COG4913    372 glplpasAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALAE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  871 EQQLTEAKVKLendIAEIMKSSGDSS------------------------AQLMKMNDELRLKERqleqIQLELTKANEK 926
Cdd:COG4913    452 ALGLDEAELPF---VGELIEVRPEEErwrgaiervlggfaltllvppehyAAALRWVNRLHLRGR----LVYERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  927 AVQLQKNVEQT-AQKAEqsqqetLKTH------QEELKKM--------QDQLTDMKKQMeTSQNQYKDLQAKYEKETSEM 991
Cdd:COG4913    525 DPERPRLDPDSlAGKLD------FKPHpfrawlEAELGRRfdyvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  992 ITKH-------DADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSV------LASARKEIELMSDKM 1058
Cdd:COG4913    598 IRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAEL 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1059 RDLISEKETLAQerntLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTekvAL 1138
Cdd:COG4913    678 ERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR---AL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1139 ISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLE--ENDRVI 1215
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLESLPEYLALLDrlEEDGLP 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 2024359624 1216 KDKDDVIQRLQSSyddlarNQRELLQEVSILTAERDSAQE 1255
Cdd:COG4913    831 EYEERFKELLNEN------SIEFVADLLSKLRRAIREIKE 864
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 336-994 6.08e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.18  E-value: 6.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  336 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDqlr 415
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  416 amVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHID 495
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQ 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  496 D---------VDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEiktlsasNERMGKENESLKTKLDH 566
Cdd:pfam05483  313 KaleedlqiaTKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-------QQRLEKNEDQLKIITME 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  567 ANKENSDVIELWKSKlesaiASHQQAMEELKVsfnkgVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEKSQHLK 645
Cdd:pfam05483  386 LQKKSSELEEMTKFK-----NNKEVELEELKK-----ILAEDEKLLDEKKQFEKIAEELKGKEQELIfLLQAREKEIHDL 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  646 EIEALKAKLLE---VTEEKEQTLENLKAKLESVEDQHLVEMEDTLNK--LQEAEIKVKELDVLQAKCNEQTKLIGSLTQQ 720
Cdd:pfam05483  456 EIQLTAIKTSEehyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKelTQEASDMTLELKKHQEDIINCKKQEERMLKQ 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  721 IRASEEKLLDL--------AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEK 792
Cdd:pfam05483  536 IENLEEKEMNLrdelesvrEEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQ 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  793 NLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLnQKEEQFALMSSEleqlksnltvmetKLKEREEREQ 872
Cdd:pfam05483  616 ENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNY-QKEIEDKKISEE-------------KLLEEVEKAK 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  873 QLTEAKVKLENDIaeimkssgdssaqlmkmndELRLKERQLEQIQL-ELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 951
Cdd:pfam05483  682 AIADEAVKLQKEI-------------------DKRCQHKIAEMVALmEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKA 742

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 2024359624  952 HQE-ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 994
Cdd:pfam05483  743 ALEiELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 791-1047 6.61e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 6.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  791 EKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER 870
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAE-------LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  871 -EQQLTEAKVK-LENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQSQQEt 948
Cdd:COG3883     88 lGERARALYRSgGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKAE- 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  949 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAE 1028
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAS 245

                          250
                   ....*....|....*....
gi 2024359624 1029 ELKKQAEQAKSLSSVLASA 1047
Cdd:COG3883    246 AAGAGAAGAAGAAAGSAGA 264
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 519-675 7.13e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.10  E-value: 7.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  519 KEHQREMSSLKEKFE---SSEEALRKEIKTLSASNERM---GKENESLKTKLDHANKENSDVIELWK------SKLESAI 586
Cdd:pfam05667  331 QQREEELEELQEQLEdleSSIQELEKEIKKLESSIKQVeeeLEELKEQNEELEKQYKVKKKTLDLLPdaeeniAKLQALV 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  587 ASHQQAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyenemsnlKLKQENEKSQHLKEIEALKAKLLEVTEE---KEQ 663
Cdd:pfam05667  411 DASAQRLVELAGQWEKHRVPLIEEYRALKEA---------------KSNKEDESQRKLEEIKELREKIKEVAEEakqKEE 475

                          170
                   ....*....|..
gi 2024359624  664 TLENLKAKLESV 675
Cdd:pfam05667  476 LYKQLVAEYERL 487
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1008-1368 7.28e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 7.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1008 DAEEALKAAQKKNDELETQAEELKKQAEQAKSlssVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1087
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKE---ELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIR 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1088 EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1167
Cdd:pfam07888  133 ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQ 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1168 SSESTLLQQLKELQANKDAVDVACqkhikerEELEHYQKLLEENDRVIKDKDDVIQRLQSSYDdlaRNQRELLQevsilt 1247
Cdd:pfam07888  213 DTITTLTQKLTTAHRKEAENEALL-------EELRSLQERLNASERKVEGLGEELSSMAAQRD---RTQAELHQ------ 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1248 aERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS----EKEMLLKSREELcvslantanenqalkLRKDEMQTELETE 1323
Cdd:pfam07888  277 -ARLQAAQLTLQLADASLALREGRARWAQERETLQQsaeaDKDRIEKLSAEL---------------QRLEERLQEERME 340

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359624 1324 REKLE-KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE 1368
Cdd:pfam07888  341 REKLEvELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 606-844 7.30e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  606 AQTAEFAELKTQMEKVKldyenemsnlklKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMED 685
Cdd:COG4942     17 AQADAAAEAEAELEQLQ------------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  686 TLNKLQeaeikvKELDVLQAKCNEQTKLIGSLTQQI----RASEEKLL-----------DLAALQKANSEGKLEIQKLSE 750
Cdd:COG4942     84 ELAELE------KEIAELRAELEAQKEELAELLRALyrlgRQPPLALLlspedfldavrRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  751 QLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsAVDGAENAQRAMQ 830
Cdd:COG4942    158 DLAELAALRAELEAER-------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELE 226

                          250
                   ....*....|....
gi 2024359624  831 ETINKLNQKEEQFA 844
Cdd:COG4942    227 ALIARLEAEAAAAA 240
PTZ00121 PTZ00121
MAEBL; Provisional
 1016-1874 7.59e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 7.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKIll 1095
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA-- 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1096 vqqdreelwtkneelnSENKKILKQKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQadllKITQENDALRSSESTLLQ 1175
Cdd:PTZ00121  1161 ----------------EDARKAEEARKAEDAKKAEAARK-----AEEVRKAEELRKAE----DARKAEAARKAEEERKAE 1215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1176 QLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQE 1255
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA 1295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1256 KDLDLKSTHIALKNEIDCLLQTNRsLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM 1335
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1336 DLKASLSSLSNFLEEMKSSREASN--SEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAftEKI 1413
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKK 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1414 NELNLEKESVFSKSLQFEKHNEAllREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEAL 1493
Cdd:PTZ00121  1453 AEEAKKAEEAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1494 EEELKKKNLENQEliacRSDLSDLLKEAQDARRTLENELAavsHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGE 1573
Cdd:PTZ00121  1531 EEAKKADEAKKAE----EKKKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE 1603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1574 VENMK-ENLTVEKKARI----LDKESFLLERMELQNNIGFLE-KEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKE 1647
Cdd:PTZ00121  1604 EKKMKaEEAKKAEEAKIkaeeLKKAEEEKKKVEQLKKKEAEEkKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1648 KMILYKETEQLASKIEQLKSdftSLSVSKAELEDVHSCVSVMLDELQHKYEVTE--KEKMELVQENESLHAEWKSLVIIn 1725
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKK---AEELKKKEAEEKKKAEELKKAEEENKIKAEEakKEAEEDKKKAEEAKKDEEEKKKI- 1759

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1726 EEILKEKEKLSKEYYKLHEKVVAllEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQTFMQKFEADKRAEE 1805
Cdd:PTZ00121  1760 AHLKKEEEKKAEEIRKEKEAVIE--EELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLVINDSKEMEDSAIKE 1834

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624 1806 VLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQnnlkNEEELTKSKELLNLENKKVE 1874
Cdd:PTZ00121  1835 VADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKED----DEEEIEEADEIEKIDKDDIE 1899
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 740-1133 7.75e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 47.64  E-value: 7.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  740 EGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKE--QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 817
Cdd:COG5185    189 LKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEalKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  818 AVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQLTEAKVKLENDIAEIMKS 891
Cdd:COG5185    269 KLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLeeqlaaAEAEQELEESKRETETGIQNLTAEIEQG 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  892 SGDSSAQLMKMNDE---------LRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQ 962
Cdd:COG5185    349 QESLTENLEAIKEEienivgeveLSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQ 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  963 LTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKgfkqnlldaeealKAAQKKNDELETQAEELKKQAEQAKS-LS 1041
Cdd:COG5185    429 IEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE-------------EAYDEINRSVRSKKEDLNEELTQIESrVS 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1042 SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1121
Cdd:COG5185    496 TLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANLRTAVIDELTQ 575

                          410
                   ....*....|..
gi 2024359624 1122 EAAEAKSRQEST 1133
Cdd:COG5185    576 YLSTIESQQARE 587
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 852-1522 8.04e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.79  E-value: 8.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  852 QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAE---IMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 928
Cdd:pfam05483  107 KLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEnkdLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  929 QLQKNVEQTAQKAEQSQQETLKTHQEelkkMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLD 1008
Cdd:pfam05483  187 DLNNNIEKMILAFEELRVQAENARLE----MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1009 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLE 1088
Cdd:pfam05483  263 LEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1089 MESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1168
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1169 SESTLLQQLKELQANKDAVDVACQKHIKEREELE-----------HYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQR 1237
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiktseeHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1238 ELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE----KEMLLKSREELCVSLANTANENQALKLRK 1313
Cdd:pfam05483  503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1314 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSE------KIHLLQEALFASEQRLlaerEELVNE 1387
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeiKVNKLELELASAKQKF----EEIIDN 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1388 NKAVTEkLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDelERKYSELLDEKKSLENAFSDMKR 1467
Cdd:pfam05483  659 YQKEIE-DKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKH--KHQYDKIIEERDSELGLYKNKEQ 735

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1468 EQEldfSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQ 1522
Cdd:pfam05483  736 EQS---SAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 703-1075 8.17e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 47.87  E-value: 8.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  703 LQAKCNEQTKLIGSlTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvSNLTKELQG 782
Cdd:PRK10246   225 LQVLTDEEKQLLTA-QQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSL---------AQPARQLRP 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  783 KEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQ---KEEQFALMSSELEQLKSNLTV 859
Cdd:PRK10246   295 HWERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTwlaEHDRFRQWNNELAGWRAQFSQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  860 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMkmndELRLKERQLEQiqlELTKANEKAVQLQKNVEQTaq 939
Cdd:PRK10246   375 QTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAAL----AQHAEQRPLRQ---RLVALHGQIVPQQKRLAQL-- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  940 kaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsEMItkhdADIKGFKQNL------------- 1006
Cdd:PRK10246   446 ------QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQE--ARI----KDLEAQRAQLqagqpcplcgsts 513

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624 1007 ---LDAEEALK--AAQKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1075
Cdd:PRK10246   514 hpaVEAYQALEpgVNQSRLDALE---KEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAV 584
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1798-1996 8.31e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 8.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1798 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1877
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1878 KEFEALkLAAAQKSQQ----------------------LAALQEENVKLAEELGRSRDEVTS-HQKLEEERSVLNNQLLE 1934
Cdd:COG4942    104 EELAEL-LRALYRLGRqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAAlRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624 1935 MKKSLpsntLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAK 1996
Cdd:COG4942    183 LEEER----AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
46 PHA02562
endonuclease subunit; Provisional
 726-1031 1.08e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  726 EKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvsnltkelQGKEQKllDLEKNLSAVNQVkdsle 805
Cdd:PHA02562   157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQ----------------QIKTYN--KNIEEQRKKNGE----- 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  806 kELQLLKEKFTSAVDGAENAqramqetinklnqkeeqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDI 885
Cdd:PHA02562   214 -NIARKQNKYDELVEEAKTI---------------------KAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  886 AEIMKssgdssaqLMKM---NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQ 960
Cdd:PHA02562   272 EQFQK--------VIKMyekGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKldTAIDELEEIMDEFNEQSKKLLELK 343

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624  961 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1031
Cdd:PHA02562   344 NKISTNKQSLITLVDKAKKVKAAIEELQAEFVD-NAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLK 413
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 744-1048 1.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  744 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGkeqklldLEKNLSAVNQVKD-SLEKELQLLKEKftsaVDGA 822
Cdd:COG3096    837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQL-------LNKLLPQANLLADeTLADRLEELREE----LDAA 905

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  823 ENAQRAMQETINKLNQKEEQFALMSSELEQLKsNLTVMETKLKEREEREQQLTEAkvklendIAEIMK-----SSGDSSA 897
Cdd:COG3096    906 QEAQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIFA-------LSEVVQrrphfSYEDAVG 977

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  898 QLMK---MNDELRlkeRQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 974
Cdd:COG3096    978 LLGEnsdLNEKLR---ARLEQAEEARREAREQLRQAQAQYSQ-YNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEA 1053

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624  975 NQykdlQAKYEK-ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK-SLSSVLASAR 1048
Cdd:COG3096   1054 EE----RARIRRdELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKaGWCAVLRLAR 1125
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 819-1182 1.09e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  819 VDGAENAQRAMQETINKLNQKEEQFALMSSELEQLksnltvmetklkerEEREQQLTEakvklENDIAeimkssgdsSAQ 898
Cdd:COG3096    284 SERALELRRELFGARRQLAEEQYRLVEMARELEEL--------------SARESDLEQ-----DYQAA---------SDH 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  899 LMKMNDELRLKERqLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQN--- 975
Cdd:COG3096    336 LNLVQTALRQQEK-IERYQEDLEELTERLEEQEEVVEE-AAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTrai 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  976 QYKD-LQAKYEKE--------TSEMITKHDADIK-----------GFKQNLLDA-------EEALKAAQKKNDELET--- 1025
Cdd:COG3096    414 QYQQaVQALEKARalcglpdlTPENAEDYLAAFRakeqqateevlELEQKLSVAdaarrqfEKAYELVCKIAGEVERsqa 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1026 ---------QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL----------ISEKETLAQERNTLKLEKESLLSQH 1086
Cdd:COG3096    494 wqtarellrRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeefcqrigqqLDAAEELEELLAELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1087 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEaKSRQESTEKVAlisEKSKLLSEIETAQADLLKITQENDAL 1166
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALE-RLREQSGEALA---DSQEVTAAMQQLLEREREATVERDEL 649

                          410
                   ....*....|....*.
gi 2024359624 1167 RSSESTLLQQLKELQA 1182
Cdd:COG3096    650 AARKQALESQIERLSQ 665
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 861-1052 1.11e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  861 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK 940
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  941 AEQSQQ--------------ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfKQNL 1006
Cdd:COG3883     95 LYRSGGsvsyldvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL-----------EALK 163

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359624 1007 LDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIE 1052
Cdd:COG3883    164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 355-702 1.14e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  355 QEALK-EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDgHDRHVLEMEAKMDQLRamveaadrekvellnqLE 433
Cdd:pfam17380  298 QERLRqEKEEKAREVERRRKLEEAEKARQ----AEMDRQAAIYAE-QERMAMERERELERIR----------------QE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  434 EEKRKVEdlqfRVEEESITkgdlevatvSEKSRIMELERDLALRVKEVAELRGRLESSKH--IDDVDTSLSLLQEISSLQ 511
Cdd:pfam17380  357 ERKRELE----RIRQEEIA---------MEISRMRELERLQMERQQKNERVRQELEAARKvkILEEERQRKIQQQKVEME 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  512 EKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTK---LDHANKENSDVIELWKSKLESAIAS 588
Cdd:pfam17380  424 QIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKkleLEKEKRDRKRAEEQRRKILEKELEE 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  589 HQQAMEElkvsfnkgvgaQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEkeqtlenl 668
Cdd:pfam17380  504 RKQAMIE-----------EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE-------- 564

                          330       340       350
                   ....*....|....*....|....*....|....
gi 2024359624  669 KAKLESVEDQhlvemEDTLNKLQEAEIKVKELDV 702
Cdd:pfam17380  565 RSRLEAMERE-----REMMRQIVESEKARAEYEA 593
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1096-1526 1.15e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1096 VQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSES--TL 1173
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1174 LQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQ-RELLQEVSILTAERDS 1252
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1253 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQ-----SEKEMLLKSREELCVSLANTAN----------------------- 1304
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSllsliltiagvlflvlgllallf 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1305 ---ENQALKLRKDEMQTELETEREKLEK------MTKDNMDLKASLSSLSNFLEEMKSSREAsNSEKIHLLQEALfasEQ 1375
Cdd:COG4717    291 lllAREKASLGKEAEELQALPALEELEEeeleelLAALGLPPDLSPEELLELLDRIEELQEL-LREAEELEEELQ---LE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1376 RLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQF-EKHNEALLREK--------DELER 1446
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELlEALDEEELEEEleeleeelEELEE 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1447 KYSELLDEKKSLENAFSDMKREQELDfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARR 1526
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGELA------------ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1490-2026 1.28e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.20  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1490 IEALEEELKKKNLE----NQELIACRSDLSDLLKEAQDarrtLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQD 1565
Cdd:PRK01156   185 IDYLEEKLKSSNLEleniKKQIADDEKSHSITLKEIER----LSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1566 KCQKLTGEVENMKENLTVEKkarildkesfllERMELQNNigflekEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVI 1645
Cdd:PRK01156   261 AESDLSMELEKNNYYKELEE------------RHMKIIND------PVYKNRNYINDYFKYKNDIENKKQILSNIDAEIN 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1646 KEKMILYK--ETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVI 1723
Cdd:PRK01156   323 KYHAIIKKlsVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1724 INEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHEL------------LLEEMSNLALKL--REIERLQ 1789
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttLGEEKSNHIINHynEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1790 AQTFMQKFEADKRAEEVLQtmekVTKEKDAIHQEKIETLAS----LENSRQTNEKLQNELDMLKQNNLKNEE--ELTKSK 1863
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVD----LKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEikNRYKSL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1864 ELLNLENKKVEELKK-------EFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1935
Cdd:PRK01156   559 KLEDLDSKRTSWLNAlavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKYNEI 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1936 K-KSLPSNTLREST--LKKEIdEERASLQKSISDTSALITQKDEELEKLRNEitvLRGENASAKTLQSVVKTLESDKLKL 2012
Cdd:PRK01156   639 QeNKILIEKLRGKIdnYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINEL 714

                          570
                   ....*....|....
gi 2024359624 2013 EEKVKNLEQKLKAK 2026
Cdd:PRK01156   715 SDRINDINETLESM 728
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
357-541 1.47e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.77  E-value: 1.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  357 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAAD 422
Cdd:COG2433    347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  423 REKVELLNQLEEEKRKVEDLQFRVEEESitkgdlevatvSEKSRIMELERDLALRVKEVAELRGRLESS-KHIDDVDTSL 501
Cdd:COG2433    427 AEVEELEAELEEKDERIERLERELSEAR-----------SEERREIRKDREISRLDREIERLERELEEErERIEELKRKL 495

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2024359624  502 SLLQEISSLqekmaaagkEHQREMSSLKEKFESSEEALRK 541
Cdd:COG2433    496 ERLKELWKL---------EHSGELVPVKVVEKFTKEAIRR 526
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1778-1984 1.61e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 1.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1778 LALKLREIERLQAQtfmqKFEADKRAEEVLQTMEKVTKEKDAIHQekietLASLENSRQTNEKLQNELdmlkqnnlkneE 1857
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREI-----------A 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1858 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEmkk 1937
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--- 748

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359624 1938 SLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNE 1984
Cdd:COG4913    749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1819-2029 1.65e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1819 AIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQ 1898
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1899 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQllemkksLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEEL 1978
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1979 EKLRNEITVLRGENASAKtlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQ 2029
Cdd:COG4942    170 EAERAELEALLAELEEER------AALEALKAERQKLLARLEKELAELAAE 214
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1108-1384 1.84e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 1.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1108 EELNSENKKILKQKEAAEAKSRQESTEKVALI--SEKSKLLSEIETAQA--DLLKITQENDALRSSESTLLQQLKELQAN 1183
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIqnAEKNILLLNQARLQAleDLEKILTEKEALQGKINILEMRLSETDAR 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1184 kdaVDVACQKHIKEREELEHYQKLLEEndrvikdkddVIQRLQSSYddlarnqrellQEVSILTAERDSAQEKDLDLKST 1263
Cdd:PLN02939   186 ---IKLAAQEKIHVEILEEQLEKLRNE----------LLIRGATEG-----------LCVHSLSKELDVLKEENMLLKDD 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1264 HIALKNEIDCLLQTNRS---LQSEKEMLLKSREEL-CVSLANTANENQALKLRKDEMQTELETEREKLEKMTK------- 1332
Cdd:PLN02939   242 IQFLKAELIEVAETEERvfkLEKERSLLDASLRELeSKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNqvekaal 321

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1333 ---DNMDLKASLSSLSNFLEEMKSSREASnsEKIHLLQEALFASEQRLLAEREEL 1384
Cdd:PLN02939   322 vldQNQDLRDKVDKLEASLKEANVSKFSS--YKVELLQQKLKLLEERLQASDHEI 374
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1546-2079 1.98e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.55  E-value: 1.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1546 FNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNnigfLEKEVEEMREKNKEFLT 1625
Cdd:TIGR04523   70 INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNK----LEKQKKENKKNIDKFLT 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1626 EKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScvsvMLDELQHKYEVTEKEKM 1705
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQIS 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1706 ELVQENESLHAEWKSLviiNEEILKEKEKLSKEYYKL------HEKVVALLEQTDADfscrLLVSEGKHELLLEEMSNLA 1779
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKK---QQEINEKTTEISNTQTQLnqlkdeQNKIKKQLSEKQKE----LEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1780 LKLREIERLQAQTFMQKF--EADKRAEEVLQTMEKVTKEKDAIHQ--EKIETL-ASLENSRQTNEKLQNELDMlKQNNLK 1854
Cdd:TIGR04523  295 SEISDLNNQKEQDWNKELksELKNQEKKLEEIQNQISQNNKIISQlnEQISQLkKELTNSESENSEKQRELEE-KQNEIE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1855 --NEEELTKSKELLNLENKKvEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK----LEEERSVL 1928
Cdd:TIGR04523  374 klKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeikdLTNQDSVK 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1929 NNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKsisdTSALITQKDEELEKLRNEITVLRGEnasaktlqsvVKTLESD 2008
Cdd:TIGR04523  453 ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKKLNEEKKELEEK----------VKDLTKK 518

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359624 2009 KLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQD---ESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQ 2079
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnleKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 955-1190 2.02e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  955 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadikgfkqnLLDAEEALKAAQKKNDELETQAEELKKQA 1034
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE---------------YNELQAELEALQAEIDKLQAEIAEAEAEI 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1035 EQAKS-LSSVLASARK--------EIELMSDKMRDLISEKETLAQerntlklekesllsqhlemeskilLVQQDREELwt 1105
Cdd:COG3883     82 EERREeLGERARALYRsggsvsylDVLLGSESFSDFLDRLSALSK------------------------IADADADLL-- 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1106 knEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKD 1185
Cdd:COG3883    136 --EELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213


                   ....*
gi 2024359624 1186 AVDVA 1190
Cdd:COG3883    214 AAAAA 218
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
609-1127 2.04e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  609 AEFAELKTQMEKVKlDYENEMSNLKLKQEneksqHLKEIEALKAKLLEVTEEKEQtLENLKAKLESVEDQhlvemedtln 688
Cdd:COG4913    225 EAADALVEHFDDLE-RAHEALEDAREQIE-----LLEPIRELAERYAAARERLAE-LEYLRAALRLWFAQ---------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  689 klQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAlQKANSEGkleiqklsEQLQAAEKQIQNLETEKVG 768
Cdd:COG4913    288 --RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA-QIRGNGG--------DRLEQLEREIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  769 GSSKVSNLTKELQGKEQKLL----DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFA 844
Cdd:COG4913    357 RERRRARLEALLAALGLPLPasaeEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  845 LMSSELEQ----LKSNLTVMETKLK-------------------ER------------EEREQQLTEA------------ 877
Cdd:COG4913    437 NIPARLLAlrdaLAEALGLDEAELPfvgelievrpeeerwrgaiERvlggfaltllvpPEHYAAALRWvnrlhlrgrlvy 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  878 -KVKLENDIAEIMKSSGDSSAQLMK---------MNDELRLK--------ERQLEQ----IQLE-LTKANEKAVQLQKnv 934
Cdd:COG4913    517 eRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawLEAELGRRfdyvcvdsPEELRRhpraITRAgQVKGNGTRHEKDD-- 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  935 eQTAQKAE----QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeKETSEMITKH---DADIKGFKQNLL 1007
Cdd:COG4913    595 -RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYswdEIDVASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1008 DAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1087
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 2024359624 1088 EMESKILLVQQDREELWtknEELNSENKKILKQKEAAEAK 1127
Cdd:COG4913    752 EERFAAALGDAVERELR---ENLEERIDALRARLNRAEEE 788
PRK01156 PRK01156
chromosome segregation protein; Provisional
 378-890 2.04e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  378 EVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADR--EKVELLNQLEEEKRKVE-DLQFRVEEESITKG 454
Cdd:PRK01156   198 ELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNElsSLEDMKNRYESEIKTAEsDLSMELEKNNYYKE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  455 DLEvatvseksRIMELERDLAL----RVKEVAELRGRLESSKHI-----------DDVDTSLSLLQEISSLQEKMAAAGK 519
Cdd:PRK01156   278 LEE--------RHMKIINDPVYknrnYINDYFKYKNDIENKKQIlsnidaeinkyHAIIKKLSVLQKDYNDYIKKKSRYD 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  520 EHQREMSSLKEkFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESaIASHQQAMEELKVS 599
Cdd:PRK01156   350 DLNNQILELEG-YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNE-INVKLQDISSKVSS 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  600 FNKGVGAQTAEFAELKTQME---------------------KVKLDYENEMSNLKLK---QENEKSQHLKEIEALKAKLL 655
Cdd:PRK01156   428 LNQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnHIINHYNEKKSRLEEKireIEIEVKDIDEKIVDLKKRKE 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  656 EVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKELDVlQAKCNEQTKLIGSLTQQIRA-SEEKLLDLAAL 734
Cdd:PRK01156   508 YLESEEINKSINEYNKIESARAD-LEDIKIKINELKDKHDKYEEIKN-RYKSLKLEDLDSKRTSWLNAlAVISLIDIETN 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  735 QKANSEgkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQgKEQKLLDLEKNLSavnQVKDSLEKELQLLKEK 814
Cdd:PRK01156   586 RSRSNE-------IKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIE-NEANNLNNKYNEI---QENKILIEKLRGKIDN 654

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624  815 FTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 890
Cdd:PRK01156   655 YKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
840-1532 2.25e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  840 EEQFALMSSELEQLKSnltvMETKLKEREEREQQLTEAKvklenDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQ 917
Cdd:COG4913    224 FEAADALVEHFDDLER----AHEALEDAREQIELLEPIR-----ELAERYAAARERLAELEYLRAALRLwfAQRRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  918 LELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQ---AKYEKETSEMITK 994
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERErrrARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  995 HDADIKGFKQN-------LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKet 1067
Cdd:COG4913    375 LPASAEEFAALraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA-- 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1068 laqerntLKLEKESL--LSQHLEMESK-----------------ILLVQQDREELWTknEELNSENKKILKQKEAAEAKS 1128
Cdd:COG4913    453 -------LGLDEAELpfVGELIEVRPEeerwrgaiervlggfalTLLVPPEHYAAAL--RWVNRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1129 RQESTEKvalISEKS---KLLSEIETAQADLLKITQENDALRSSESTllqqlKELQANKDAVDVACQ-KHIKEREELEHY 1204
Cdd:COG4913    524 PDPERPR---LDPDSlagKLDFKPHPFRAWLEAELGRRFDYVCVDSP-----EELRRHPRAITRAGQvKGNGTRHEKDDR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1205 QKLLEE------NDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQ------EKDLDLKSTHIALkneid 1272
Cdd:COG4913    596 RRIRSRyvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeysWDEIDVASAEREI----- 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1273 cllqtnRSLQSEKEMLLKSREELcvslantanenQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMK 1352
Cdd:COG4913    671 ------AELEAELERLDASSDDL-----------AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1353 SSREASNSEKIHLLQEALfasEQRLLAE---------REELVNENKAVTEKLTKATADAVLAETAFTEK----INELNLE 1419
Cdd:COG4913    734 DRLEAAEDLARLELRALL---EERFAAAlgdaverelRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDAD 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1420 KESVFskslQFEKHNEALlrEKDELERKYSELLDEKKSLENAF-----SDMKREQEldfSAKRLLVQENTTLK------- 1487
Cdd:COG4913    811 LESLP----EYLALLDRL--EEDGLPEYEERFKELLNENSIEFvadllSKLRRAIR---EIKERIDPLNDSLKripfgpg 881

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359624 1488 --YSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENEL 1532
Cdd:COG4913    882 ryLRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1415-1846 2.40e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1415 ELNLEKESVFSKSLQFEK-HNEALLREKDE----LERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYS 1489
Cdd:pfam01576  109 EEQLDEEEAARQKLQLEKvTTEAKIKKLEEdillLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1490 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK 1569
Cdd:pfam01576  189 ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1570 LTGEVENMKENLTVEKKARILDK-------ESFLLERMELQNNIGFL----------EKEVEEMREKNKEFLTEKELLVQ 1632
Cdd:pfam01576  269 LEAQISELQEDLESERAARNKAEkqrrdlgEELEALKTELEDTLDTTaaqqelrskrEQEVTELKKALEEETRSHEAQLQ 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1633 EKEKSET--------KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1704
Cdd:pfam01576  349 EMRQKHTqaleelteQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1705 MELVQENESLHAEWKSLVIINEEILKEKEKLSKEY----YKLHEKVVALLEQTDA--DFSCRLLVSEGKHELLLEEMSNL 1778
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVssleSQLQDTQELLQEETRQklNLSTRLRQLEDERNSLQEQLEEE 508

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359624 1779 ALKLREIERLQAQTFMQKFEADKRAEEVLQTME-------KVTKEKDAIHQEKIETLASLENSRQTNEKLQNELD 1846
Cdd:pfam01576  509 EEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkkRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 731-891 3.01e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  731 LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKD--SLEKEL 808
Cdd:COG1579     19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  809 QLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEI 888
Cdd:COG1579     99 ESLKRR-------ISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELEELEAEREEL 168


                   ...
gi 2024359624  889 MKS 891
Cdd:COG1579    169 AAK 171
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1772-1990 3.47e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1772 LEEMSNLALKLRE-IERLQaqtfmqkfeadkRAEEVLQTMEKVTKEKDaiHQEKIETLASLENSRQTNEKLQNELDmlkq 1850
Cdd:COG4913    237 LERAHEALEDAREqIELLE------------PIRELAERYAAARERLA--ELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1851 nnlKNEEELTKSKELLNLENKKVEELKKEFEALKLA-AAQKSQQLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLN 1929
Cdd:COG4913    299 ---ELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERR---RARLEALLAALG 372

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1930 NQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRG 1990
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1797-2032 3.70e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.66  E-value: 3.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1797 FEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKEllnlENKKVEEL 1876
Cdd:PLN02939   124 QLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQ----EKIHVEIL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1877 KKEFEALKLAAAQK-----------SQQLAALQEENVKLAEELGRSRDEVTSHQ-------KLEEERSVLNNQLLEMKKS 1938
Cdd:PLN02939   200 EEQLEKLRNELLIRgateglcvhslSKELDVLKEENMLLKDDIQFLKAELIEVAeteervfKLEKERSLLDASLRELESK 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1939 L---PSNTLRESTLKKEIDEERA-SLQ------KSISDTSALITQKDEELEKLRNEItvlrgeNASAKtlQSVVKTLESD 2008
Cdd:PLN02939   280 FivaQEDVSKLSPLQYDCWWEKVeNLQdlldraTNQVEKAALVLDQNQDLRDKVDKL------EASLK--EANVSKFSSY 351

                          250       260
                   ....*....|....*....|....*
gi 2024359624 2009 KLKL-EEKVKNLEQKLKAKSEQPLT 2032
Cdd:PLN02939   352 KVELlQQKLKLLEERLQASDHEIHS 376
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
756-1089 4.29e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.89  E-value: 4.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  756 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 835
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  836 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 915
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  916 IQLELTKANEKAV--QLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMIT 993
Cdd:COG4372    169 LEQELQALSEAEAeqALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  994 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERN 1073
Cdd:COG4372    249 EELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKL 328

                          330
                   ....*....|....*.
gi 2024359624 1074 TLKLEKESLLSQHLEM 1089
Cdd:COG4372    329 ELALAILLAELADLLQ 344
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
337-534 4.82e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 4.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALVRDGHDRhVLEMEAKMDQLRA 416
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  417 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESitkgdlevATVSEKSRIMELERDLALrvkevAELRGRLESSKHIDD 496
Cdd:COG4913    700 ELEELEEELDELKGEIGRLEKELEQAEEELDELQ--------DRLEAAEDLARLELRALL-----EERFAAALGDAVERE 766

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 2024359624  497 VDTSLSllQEISSLQEKMAAAGKEHQREMSSLKEKFES 534
Cdd:COG4913    767 LRENLE--ERIDALRARLNRAEEELERAMRAFNREWPA 802
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 662-1030 5.33e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.43  E-value: 5.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  662 EQTLENLKA-----KLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 736
Cdd:PRK10929    29 TQELEQAKAaktpaQAEIVE-----ALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  737 ANsEGKLEIQKLSEQLQAAEKQIQNlETEKVGGSSKVSNLTKELQGKEQKLL-DLEKNLSAVNQVKDSLEK-ELQLLKek 814
Cdd:PRK10929   104 TD-ALEQEILQVSSQLLEKSRQAQQ-EQDRAREISDSLSQLPQQQTEARRQLnEIERRLQTLGTPNTPLAQaQLTALQ-- 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  815 ftsavdgAENAQRAMQetINKLnqkeeqfalmssELEQLKSN----LTVMETKL--KEREEREQQLTEAKVKLENDIAEI 888
Cdd:PRK10929   180 -------AESAALKAL--VDEL------------ELAQLSANnrqeLARLRSELakKRSQQLDAYLQALRNQLNSQRQRE 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  889 MKSSGDSSAQLMKMNDElrLKERQLEQIQL--ELTKA-NEKAVQLQKNVEQTAQKAEQSQQ--ETLKTHQEE-------- 955
Cdd:PRK10929   239 AERALESTELLAEQSGD--LPKSIVAQFKInrELSQAlNQQAQRMDLIASQQRQAASQTLQvrQALNTLREQsqwlgvsn 316

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  956 -----LKKMQDQLTDMKK--QMETSQNQYKDLQAKYEketsEMITKHDADikgfKQNLLDAEEALKAAQKK--NDELETQ 1026
Cdd:PRK10929   317 algeaLRAQVARLPEMPKpqQLDTEMAQLRVQRLRYE----DLLNKQPQL----RQIRQADGQPLTAEQNRilDAQLRTQ 388


                   ....
gi 2024359624 1027 AEEL 1030
Cdd:PRK10929   389 RELL 392
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2109-2126 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359624 2109 RLFCDICGCFDlHDTEDC 2126
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
46 PHA02562
endonuclease subunit; Provisional
 945-1211 5.68e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 5.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  945 QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsEMITKHDADIKGFKQNLLDAEEALKAAQKkndELE 1024
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLNLVM---DIE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1025 TQAEELKKQAEQAKSLSSVLASARKEIELMSDK------MRDLISEKETLAQERNTLKlekesllsqhlEMESKILLVQQ 1098
Cdd:PHA02562   252 DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLK-----------ELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1099 DREELWTKNEELNSENKKILKQKeaaeAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEndalrssestllqqLK 1178
Cdd:PHA02562   321 AIDELEEIMDEFNEQSKKLLELK----NKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE--------------LA 382

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2024359624 1179 ELQANKDAVDVACQKHIKEREELEHYQKLLEEN 1211
Cdd:PHA02562   383 KLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 651-1064 5.73e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 44.83  E-value: 5.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  651 KAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEdtlNKLQEAEIKVKELDVLQAK--CNEQTKLIGSLTQQIRASEEKL 728
Cdd:PRK04778    52 KVKKLNLTGQSEEKFEEWRQKWDEIVTNSLPDIE---EQLFEAEELNDKFRFRKAKheINEIESLLDLIEEDIEQILEEL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  729 LDLAALQKANSEGKLEIQKLSEQLQAA---------------EKQIQNLETEKvggsSKVSNLTKE---LQGKEQkLLDL 790
Cdd:PRK04778   129 QELLESEEKNREEVEQLKDLYRELRKSllanrfsfgpaldelEKQLENLEEEF----SQFVELTESgdyVEAREI-LDQL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  791 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQE--------TINK-LNQKEEQFALMSSELEQLKsnLTVME 861
Cdd:PRK04778   204 EEELAALEQIMEEIPELLKELQTELPDQLQELKAGYRELVEegyhldhlDIEKeIQDLKEQIDENLALLEELD--LDEAE 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  862 TKLKEREEREQQL---TEAKVKLENDIAEIMKSSGDSSAQLMKMNDELrlkerqleqiQLELTkanekavQLQKNVEQTA 938
Cdd:PRK04778   282 EKNEEIQERIDQLydiLEREVKARKYVEKNSDTLPDFLEHAKEQNKEL----------KEEID-------RVKQSYTLNE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  939 qkaeqSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEALKAAQK 1018
Cdd:PRK04778   345 -----SELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELE-EILKQLEEIEKEQEKLSEMLQGLRKDELEARE 418

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359624 1019 KNDELETQAEELKKQAEQAKsLSSVLASARKEIELMSDKMRDLISE 1064
Cdd:PRK04778   419 KLERYRNKLHEIKRYLEKSN-LPGLPEDYLEMFFEVSDEIEALAEE 463
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
353-891 7.86e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEmeaKMDQLRAMVEAADREKVELLNQL 432
Cdd:COG4913    285 FAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGD---RLEQLEREIERLERELEERERRR 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  433 EEEKRKVEDLQFRVEEEsitkgdlevatvseksrimelERDLALRVKEVAELRGRLEsskhiddvdtslsllQEISSLQE 512
Cdd:COG4913    362 ARLEALLAALGLPLPAS---------------------AEEFAALRAEAAALLEALE---------------EELEALEE 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  513 KMAAAGKEHQRemssLKEKFesseEALRKEIKTLSASNERMGKENESLKTKL-DHANKENSDV------IEL------WK 579
Cdd:COG4913    406 ALAEAEAALRD----LRREL----RELEAEIASLERRKSNIPARLLALRDALaEALGLDEAELpfvgelIEVrpeeerWR 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  580 SKLESAIasHQQAMeELKVSfnkgvGAQTAEFAEL--KTQMeKVKLDYEnemsnlklkQENEKSQHLKEIEALKAKLLEV 657
Cdd:COG4913    478 GAIERVL--GGFAL-TLLVP-----PEHYAAALRWvnRLHL-RGRLVYE---------RVRTGLPDPERPRLDPDSLAGK 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  658 TEEKEQTLEN-LKAKLESVEDQHLVEMEDTLNKLQEA------------------------------------EIKVKEL 700
Cdd:COG4913    540 LDFKPHPFRAwLEAELGRRFDYVCVDSPEELRRHPRAitragqvkgngtrhekddrrrirsryvlgfdnraklAALEAEL 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  701 DVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEgKLEIQKLSEQLQAAEKQIQNLETekvgGSSKVSNLTKEL 780
Cdd:COG4913    620 AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWD-EIDVASAEREIAELEAELERLDA----SSDDLAALEEQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  781 QGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAmqetinklnQKEEQFALMSSELEQLKSNlTVM 860
Cdd:COG4913    695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL---------ARLELRALLEERFAAALGD-AVE 764

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2024359624  861 ETKLKEREEREQQLTEAKVKLENDIAEIMKS 891
Cdd:COG4913    765 RELRENLEERIDALRARLNRAEEELERAMRA 795
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1555-1818 8.74e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 8.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1555 ILNRERTELQDKCQKLtG--EVENMKENLTVEkkaRILDKESfllERMELQNNIGFLEKEVEemreknKEFLTEKELLVQ 1632
Cdd:PRK05771    13 TLKSYKDEVLEALHEL-GvvHIEDLKEELSNE---RLRKLRS---LLTKLSEALDKLRSYLP------KLNPLREEKKKV 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1633 EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScVSVMLDELQHK-------YEVTEKEKM 1705
Cdd:PRK05771    80 SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGFkyvsvfvGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1706 ELVQENESLHAEWKS-------LVIINEeilkekeklsKEYYKLHEKVVAlleqtDADFScRLLVSEGKH--ELLLEEMS 1776
Cdd:PRK05771   159 ELKLESDVENVEYIStdkgyvyVVVVVL----------KELSDEVEEELK-----KLGFE-RLELEEEGTpsELIREIKE 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359624 1777 NLALKLREIERLQAQTfmqKFEADKRAEEVLQTMEKVTKEKD 1818
Cdd:PRK05771   223 ELEEIEKERESLLEEL---KELAKKYLEELLALYEYLEIELE 261
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
504-946 9.14e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 9.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  504 LQEISSLQEKMAAAGKEHQ--REMSSLKEKFESSEEALRKEIKTLSASNERMGK--ENESLKTKLDHANKENSDVIELWK 579
Cdd:COG4717     70 LKELKELEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  580 sKLESAIASHQQAMEELKvsfnkgvgAQTAEFAELKTQMEkvklDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE 659
Cdd:COG4717    150 -ELEERLEELRELEEELE--------ELEAELAELQEELE----ELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  660 EKEQTLENLKAKLESVEDQHlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQ--QIRASEEKLLDLAALQKA 737
Cdd:COG4717    217 EAQEELEELEEELEQLENEL--EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiaGVLFLVLGLLALLFLLLA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  738 NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEqkLLDLEKNLSAVNQVKDSLEKELQL------L 811
Cdd:COG4717    295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE--LLDRIEELQELLREAEELEEELQLeeleqeI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  812 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM--ETKLKEREEREQQLTEAKVKLENDIAEIM 889
Cdd:COG4717    373 AALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEELEEELEELEEELEELR 452

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624  890 KSSGDSSAQLMKMN-----DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQ 946
Cdd:COG4717    453 EELAELEAELEQLEedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
790-1109 9.35e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 9.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  790 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 869
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  870 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETL 949
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  950 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEE 1029
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1030 LKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1109
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1022-1623 9.62e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 9.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1022 ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDkMRDLISEKETLAQERNTLKLEKESLlsQHLEMESKILLVQQDRE 1101
Cdd:COG4913    222 DTFEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1102 ELwtkneelnsenkkilkQKEAAEAKSRQESTEKvalisekskllsEIETAQADLLKITQendALRSSESTLLQQLKELQ 1181
Cdd:COG4913    299 EL----------------RAELARLEAELERLEA------------RLDALREELDELEA---QIRGNGGDRLEQLEREI 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1182 ANKdavdvacQKHIKERE-ELEHYQKLLEendrvikdkdDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1260
Cdd:COG4913    348 ERL-------ERELEERErRRARLEALLA----------ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1261 KSTHIALKNEIDCLLQTNRSLQSEK----EMLLKSREELCvslantanenQALKLRKDE-------MQTELETER----- 1324
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKsnipARLLALRDALA----------EALGLDEAElpfvgelIEVRPEEERwrgai 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1325 ---------------EKLEKMTK--DNMDLKASLSS--LSNFLEEMKSSREASNS--EKIHLLQEALFASEQRLLAER-- 1381
Cdd:COG4913    481 ervlggfaltllvppEHYAAALRwvNRLHLRGRLVYerVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAWLEAELGRRfd 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1382 -------EELVNENKAVT-EKLTKATADA-------------VLAETAfTEKINELNLEKesvfskslqfekhnEALLRE 1440
Cdd:COG4913    561 yvcvdspEELRRHPRAITrAGQVKGNGTRhekddrrrirsryVLGFDN-RAKLAALEAEL--------------AELEEE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1441 KDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIAcrsdLSDLLKE 1520
Cdd:COG4913    626 LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-----IAELEAELERLDASSDDLAA----LEEQLEE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1521 AQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK-LTGEVENMKENLTVEKKARILdKESFLLER 1599
Cdd:COG4913    697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVEREL-RENLEERI 775

                          650       660
                   ....*....|....*....|....*
gi 2024359624 1600 MELQNNIGFLEKEVEE-MREKNKEF 1623
Cdd:COG4913    776 DALRARLNRAEEELERaMRAFNREW 800
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 817-1047 1.00e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  817 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDsS 896
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE-R 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  897 AQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLKTHQEELKKMQDQLTDMKKQMETSQ 974
Cdd:COG3883     92 ARALYRSGGSVSYLDVLLGSE-SFSDFLDRLSALSKIADADADLLEElkADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359624  975 NQYKDLQAKYEKETsemitkhdADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1047
Cdd:COG3883    171 AELEAQQAEQEALL--------AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 646-794 1.06e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 44.30  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  646 EIEALKAKLLEVTEEKEQtlenLKAKLESVEDQHLVEMEDTLNKLQEaeikvkELDVLQAKCNEQTKLIGSLTQQIRASE 725
Cdd:COG0542    412 ELDELERRLEQLEIEKEA----LKKEQDEASFERLAELRDELAELEE------ELEALKARWEAEKELIEEIQELKEELE 481

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624  726 EKLLDLAALQKAnsegkleiqklSEQLQAAEKQIQNLETEKVGGS---SKVSNLT-----KELQGKEQKLLDLEKNL 794
Cdd:COG0542    482 QRYGKIPELEKE-----------LAELEEELAELAPLLREEVTEEdiaEVVSRWTgipvgKLLEGEREKLLNLEEEL 547
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1021-1408 1.09e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.90  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1021 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1100
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1101 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1180
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRL 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1181 QANKDAVDVACQKHIKEREELEhyqKLLEENDRVIkdkDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1260
Cdd:pfam19220  180 QALSEEQAAELAELTRRLAELE---TQLDATRARL---RALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEAL 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1261 KSTHIALkneiDCLLQTNRSLQSEKEMLLKSREElcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKAS 1340
Cdd:pfam19220  254 TARAAAT----EQLLAEARNQLRDRDEAIRAAER---RLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEER 326

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624 1341 LSSLSNFLEEmKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETA 1408
Cdd:pfam19220  327 AEMLTKALAA-KDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERALAQGA 393
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 716-995 1.11e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  716 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 795
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  796 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 870
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  871 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 948
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359624  949 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 995
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
PRK12704 PRK12704
phosphodiesterase; Provisional
 612-748 1.16e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  612 AELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKLESVEDQHLVEMEDTLNKLQ 691
Cdd:PRK12704    49 KEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQ----KEENLDRKLELLEKREEELEKKEKELEQKQQ 124

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624  692 EAEIKVKELDVLQAKCNEQTKLIGSLTQqirasEE--KLLdlaaLQKANSEGKLEIQKL 748
Cdd:PRK12704   125 ELEKKEEELEELIEEQLQELERISGLTA-----EEakEIL----LEKVEEEARHEAAVL 174
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1847-2079 1.17e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1847 MLKQNNLKNEEELTKSKELLNlenKKVEELKKEFEAL--KLAAAQKSQQLAALQEENVKLAEELGRSRDEVTshqKLEEE 1924
Cdd:COG3206    161 YLEQNLELRREEARKALEFLE---EQLPELRKELEEAeaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLA---EARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1925 RSVLNNQLLEMKKSLPSN-----TLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGEnaSAKTLQ 1999
Cdd:COG3206    235 LAEAEARLAALRAQLGSGpdalpELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ--LQQEAQ 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 2000 SVVKTLESDKLKLEEKVKNLEQKLKAKSEQpltvtspsgdiAANLLQDES-AEDKQQEIDFLNSVIVDLQRRNEELNLKI 2078
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEAR-----------LAELPELEAeLRRLEREVEVARELYESLLQRLEEARLAE 381


                   .
gi 2024359624 2079 Q 2079
Cdd:COG3206    382 A 382
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
647-920 1.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  647 IEALKAKLLEVTEEkeqtLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEE 726
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAEL-----DALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  727 KLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKnlSAVNQVKDSLEK 806
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-------LEQAEEELDELQDRLEAAED--LARLELRALLEE 753

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  807 EL-QLLKEKFTSAVdgAENAQRAMQETINKLNQKEEQFA-LMSSELEQLKSNLTVMETKLKEREEREQQLTEAK----VK 880
Cdd:COG4913    754 RFaAALGDAVEREL--RENLEERIDALRARLNRAEEELErAMRAFNREWPAETADLDADLESLPEYLALLDRLEedglPE 831

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359624  881 LENDIAE-IMKSSGDSSAQL-MKMNDELRLKERQLEQIQLEL 920
Cdd:COG4913    832 YEERFKElLNENSIEFVADLlSKLRRAIREIKERIDPLNDSL 873
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 416-807 1.21e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.07  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  416 AMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSeKSRIMELErdlalrvKEVAELRGRLESSKHID 495
Cdd:PLN03229   381 NMDELGKMDTEELLKHRMLKFRKIGGFQEGVPVDPERKVNMKKREAV-KTPVRELE-------GEVEKLKEQILKAKESS 452

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  496 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSsLKEKFESseeaLRKEIKTLSASNERMgkeNESLKTKLDHANKEnsdvi 575
Cdd:PLN03229   453 SKPSELALNEMIEKLKKEIDLEYTEAVIAMG-LQERLEN----LREEFSKANSQDQLM---HPVLMEKIEKLKDE----- 519

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  576 elWKSKLESA--IASHQQAMEELKvSFNKGVGAqtaefAELKTQMEKVKLDYenemsNLKLKQENEKSQHLKEIEALKAK 653
Cdd:PLN03229   520 --FNKRLSRApnYLSLKYKLDMLN-EFSRAKAL-----SEKKSKAEKLKAEI-----NKKFKEVMDRPEIKEKMEALKAE 586

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  654 LLEVTEEKEQTL-ENLKAKLESVEDQHLVEMEDTLNK--LQEAEIKVKELDVLQAKCNEQTKL-IGSLTQQIRASEEKLL 729
Cdd:PLN03229   587 VASSGASSGDELdDDLKEKVEKMKKEIELELAGVLKSmgLEVIGVTKKNKDTAEQTPPPNLQEkIESLNEEINKKIERVI 666

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624  730 DLAALQKANSEGKLEIQKLSEQLQAAEKQ-IQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKE 807
Cdd:PLN03229   667 RSSDLKSKIELLKLEVAKASKTPDVTEKEkIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARETAAESNGSLKND 745
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
785-1259 1.24e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  785 QKLLDLEKNLSAVNQVKDSLEkELQLLKEKFTSAVDGAEnAQRAMQETINKLnQKEEQFALMSSELEQLKSNLTVMETKL 864
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLA-ELEYLRAALRLW-FAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  865 KEREEREQQLTEAKVKLENDIAEimkSSGDSSAQLMKmndELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ--KAE 942
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRG---NGGDRLEQLER---EIERLERELEERERRRARLEALLAALGLPLPASAEefAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  943 QSQ-QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAkyeketsemitkhdaDIKGFKQN-------LLDAEEALK 1014
Cdd:COG4913    386 RAEaAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---------------EIASLERRksniparLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1015 AA-QKKNDELETQAEELKKQAEQAK--------------SL---SSVLASARKEIE-------LMSDKMRDLISEKETLA 1069
Cdd:COG4913    451 EAlGLDEAELPFVGELIEVRPEEERwrgaiervlggfalTLlvpPEHYAAALRWVNrlhlrgrLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1070 QERNTL--KLE-KESLLSQHLEME--SKILLVQQDREE--------------------LWTKNEE----------LNSEN 1114
Cdd:COG4913    531 LDPDSLagKLDfKPHPFRAWLEAElgRRFDYVCVDSPEelrrhpraitragqvkgngtRHEKDDRrrirsryvlgFDNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1115 KKILKQKEAAEAKSR-QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL---QQLKELQANKDAVDVA 1190
Cdd:COG4913    611 KLAALEAELAELEEElAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSDDLAAL 690

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624 1191 cqkhikeREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLD 1259
Cdd:COG4913    691 -------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
PRK12704 PRK12704
phosphodiesterase; Provisional
 1781-1903 1.44e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1781 KLREIERlQAQTFMQkfEADKRAEEVLQtmEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdMLKQNNLKN----- 1855
Cdd:PRK12704    32 KIKEAEE-EAKRILE--EAKKEAEAIKK--EALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL-LQKEENLDRklell 105

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359624 1856 ---EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1903
Cdd:PRK12704   106 ekrEEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK 156
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1119-1358 1.69e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1119 KQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQLKELQANkdavdvacqkhikeR 1198
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAELAEL--------------E 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1199 EELEHYQKLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAerdsaqekdldLKSTHIALKNEIDCLLQT 1277
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLQY-----------LKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1278 NRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREA 1357
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   .
gi 2024359624 1358 S 1358
Cdd:COG4942    239 A 239
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1357-1579 2.35e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1357 ASNSEKIHLLQEALFASEQRLlAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEA 1436
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEI-AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1437 LLREKDELERKYSELLDE--KKSLENAFSDMKREQELDFSAKRL--LVQENTTLKYSIEALEEELKKKNLENQELIACRS 1512
Cdd:COG4942     95 LRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359624 1513 DLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKE 1579
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1601-1999 2.64e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1601 ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAele 1680
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1681 dvhscvsvmLDELQHKYEVTEKEKMELVQENESLHAEWKSLviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCR 1760
Cdd:COG4717    127 ---------LLPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLSLATEEE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1761 LLVSEGKHELLLEEMSNL--ALKLREIERLQAQTFMQKFEADKRAEEVLQTMEK-------------------------- 1812
Cdd:COG4717    194 LQDLAEELEELQQRLAELeeELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallallglggsllslil 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1813 -------------------VTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1873
Cdd:COG4717    274 tiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1874 EELKKEFEALKLAAAQKSQQlAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESTLKKEI 1953
Cdd:COG4717    354 REAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEEL 430

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359624 1954 DEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQ 1999
Cdd:COG4717    431 EEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
PTZ00121 PTZ00121
MAEBL; Provisional
 1783-2025 2.72e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1783 REIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKS 1862
Cdd:PTZ00121  1278 RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1863 KELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSN 1942
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1943 TLRESTLKKEIDEERASLQKSISDtsalITQKDEELEKLRNeitvLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQK 2022
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAEE----AKKKAEEAKKADE----AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509


                   ...
gi 2024359624 2023 LKA 2025
Cdd:PTZ00121  1510 KKA 1512
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1412-1879 2.81e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 2.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1412 KINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIE 1491
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1492 ALEEELKK-----KNLENQeLIACRSDLSDLLKE-AQDARRTLENELAAVSHAKQVLSS-------SFNTCSSDIEILNR 1558
Cdd:TIGR04523  271 EKQKELEQnnkkiKELEKQ-LNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNqisqnnkIISQLNEQISQLKK 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1559 ERTELQDKCQKLTGEVENMKENLTVEKKarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSE 1638
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKK----ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1639 TKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM-------LDELQHKYEVTEKEKMELVQEN 1711
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEK 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1712 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADfscrllVSEGKHELLLEEMSNLALKLREIERLQAQ 1791
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD------DFELKKENLEKEIDEKNKEIEELKQTQKS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1792 TFMQKFEADKRAEEVLQTMEKVTKEKdaihQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENK 1871
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIKEI----EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655


                   ....*...
gi 2024359624 1872 KVEELKKE 1879
Cdd:TIGR04523  656 EIRNKWPE 663
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
714-1181 3.03e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  714 IGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS--SKVSNLTKELQGKEQKLLDLE 791
Cdd:COG4717     73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEELE 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  792 KNLSAVNQvkdsLEKELQLLKEKftsavdgAENAQRAMQETINKLNQKEEQfalmssELEQLKSNLTVMETKLKEREERE 871
Cdd:COG4717    153 ERLEELRE----LEEELEELEAE-------LAELQEELEELLEQLSLATEE------ELQDLAEELEELQQRLAELEEEL 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  872 QQLTEAKVKLENDIAEImkssgdsSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 951
Cdd:COG4717    216 EEAQEELEELEEELEQL-------ENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAL 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  952 HQEELKKMQDQLTDMKKQMEtSQNQYKDLQakyEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1031
Cdd:COG4717    289 LFLLLAREKASLGKEAEELQ-ALPALEELE---EEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1032 KQ---AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILlvQQDREELWTKNE 1108
Cdd:COG4717    365 LEeleQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEL--EEELEELEEELE 442

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359624 1109 ELNSENKKILKQKEAAEAKSRQESTEKvalisEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQ 1181
Cdd:COG4717    443 ELEEELEELREELAELEAELEQLEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYR 510
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 537-858 3.20e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.64  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  537 EALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAE----FA 612
Cdd:COG5185    242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  613 ELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEqtLENLKAKLESVEDQHLVEMEDTLNKLQE 692
Cdd:COG5185    322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  693 AEIKVKELDVLQAKcneqtkligSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSK 772
Cdd:COG5185    400 QRGYAQEILATLED---------TLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYD 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  773 VSNltkelQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 852
Cdd:COG5185    471 EIN-----RSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLI 545


                   ....*.
gi 2024359624  853 LKSNLT 858
Cdd:COG5185    546 PASELI 551
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 742-911 3.37e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  742 KLEIQKLSEQLQAAEKQIQNLETEkvggsskvsnltKELQGKEQKLLDLEKnlsavnqvKDSLEKELQLLKEKFtsavDG 821
Cdd:COG0542    403 RMEIDSKPEELDELERRLEQLEIE------------KEALKKEQDEASFER--------LAELRDELAELEEEL----EA 458

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  822 AENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEreerEQQLTEAKVKlENDIAEIM-KSSG------- 893
Cdd:COG0542    459 LKARWEAEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAE----LAPLLREEVT-EEDIAEVVsRWTGipvgkll 533

                          170
                   ....*....|....*....
gi 2024359624  894 -DSSAQLMKMNDElrLKER 911
Cdd:COG0542    534 eGEREKLLNLEEE--LHER 550
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 682-965 3.37e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  682 EMEDTLNKLQEAEIkVKELDVLQAKCNEQTKLIGSLTQQIraseEKLLDLaaLQKANSEGKLEIQKLSE-QLQAAEKQIQ 760
Cdd:PRK05771    17 YKDEVLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKL----SEALDK--LRSYLPKLNPLREEKKKvSVKSLEELIK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  761 NLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDsLEKELQLLKE-KFTSAVDGaenaqramqeTINKlNQK 839
Cdd:PRK05771    90 DVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGfKYVSVFVG----------TVPE-DKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  840 EEQFALMSS----ELEQLKSNLTVMETKLKEREEreQQLTEAKvKLENDIAEImKSSGDSSAQLMKMNDELRLKERQLEQ 915
Cdd:PRK05771   158 EELKLESDVenveYISTDKGYVYVVVVVLKELSD--EVEEELK-KLGFERLEL-EEEGTPSELIREIKEELEEIEKERES 233

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624  916 IQLELTKANEKAVQLQKNV----EQTAQKAEQSQQ--ETLKT----------HQEELKKMQDQLTD 965
Cdd:PRK05771   234 LLEELKELAKKYLEELLALyeylEIELERAEALSKflKTDKTfaiegwvpedRVKKLKELIDKATG 299
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 1588-2014 3.50e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 42.63  E-value: 3.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1588 RILDKESFLLERME-----------LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETE 1656
Cdd:pfam15818    1 QLLDFKTSLLEALEelrmrreaetqYEEQIGKIIVETQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQMKMCALEEEK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1657 ---QLASK-----IEQLKSDFTSLSVSKAELEDVhscVSVMLDELQ----------------HKYEVTEKEKMELVQEN- 1711
Cdd:pfam15818   81 gkyQLATEikekeIEGLKETLKALQVSKYSLQKK---VSEMEQKLQlhllakedhhkqlneiEKYYATITGQFGLVKENh 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1712 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvvalLEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQ 1791
Cdd:pfam15818  158 GKLEQNVQEAIQLNKRLSALNKKQESEICSLKKE----LKKVTSDLIKSKVTCQYKMG---EENINLTIKEQKFQELQER 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1792 TFMQkfeadkraeevLQTMEKVTKEKDAIHQEKIETLAS-------LENSRQTNEKLQNELDMLKQNN--LKNEEELTKS 1862
Cdd:pfam15818  231 LNME-----------LELNKKINEEITHIQEEKQDIIISfqhmqqlLQQQTQANTEMEAELKALKENNqtLERDNELQRE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1863 K------ELLNLENKKVEEL---KKEFEALKLAAAQKSQQLAALQEENVKLAEElgrsRDEVTSHQKLEEERSVLNNQLL 1933
Cdd:pfam15818  300 KvkeneeKFLNLQNEHEKALgtwKKHVEELNGEINEIKNELSSLKETHIKLQEH----YNKLCNQKKFEEDKKFQNVPEV 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1934 EMKKS-LPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKL 2012
Cdd:pfam15818  376 NNENSeMSTEKSENLIIQKYNSEQEIREENTKSFCSDTEYRETEKKKGPPVEEIIIEDLQVLEKSFKNEIDTSVPQDKNQ 455


                   ..
gi 2024359624 2013 EE 2014
Cdd:pfam15818  456 SE 457
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1822-1940 3.52e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 3.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1822 QEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQ-LAALQE 1899
Cdd:PRK00409   515 KEKLNELiASLEELERELEQKAEEAEALLKEAEKLKEEL----------EEKKEKLQEEEDKLLEEAEKEAQQaIKEAKK 584

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2024359624 1900 ENVKLAEELGRSRDEVTSHQK---LEEERSVLNNQLLEMKKSLP 1940
Cdd:PRK00409   585 EADEIIKELRQLQKGGYASVKaheLIEARKRLNKANEKKEKKKK 628
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 653-1085 3.63e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 3.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  653 KLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEAEikvKELDV-LQAkCNEQTKLIGSLTQQIRASEEKLLDL 731
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL-VEMARELEELSARE---SDLEQdYQA-ASDHLNLVQTALRQQEKIERYQEDL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  732 AALqkansEGKLEIQklSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLldleknlsavnqvkdsleKELQLL 811
Cdd:COG3096    357 EEL-----TERLEEQ--EEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAL------------------DVQQTR 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  812 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKS 891
Cdd:COG3096    412 AIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  892 SGDSSA-QLMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQSQ------QETLKTHQEELKKMQDQLT 964
Cdd:COG3096    492 QAWQTArELLRRYRSQQALAQRLQQLRAQLAEL-EQRLRQQQNAERLLEEFCQRIgqqldaAEELEELLAELEAQLEELE 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  965 DmkkQMETSQNQYKDLQAKyeketsemitkhdadikgfkqnlldaEEALKAAQKkndELETQAEELKKQAEQAKSLSSVL 1044
Cdd:COG3096    571 E---QAAEAVEQRSELRQQ--------------------------LEQLRARIK---ELAARAPAWLAAQDALERLREQS 618

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2024359624 1045 ASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1085
Cdd:COG3096    619 GEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQ 659
PRK11281 PRK11281
mechanosensitive channel MscK;
1803-1974 3.70e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1803 AEEVLQTMEKVTKEKDAIHQEK---------IETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKskellnLENKKV 1873
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKlvqqdleqtLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA------LKDDND 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1874 EELKKEFEALKLAA-----AQKSQQLAALQE------------------------ENVKLAEEL---------GRSRDEV 1915
Cdd:PRK11281   112 EETRETLSTLSLRQlesrlAQTLDQLQNAQNdlaeynsqlvslqtqperaqaalyANSQRLQQIrnllkggkvGGKALRP 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359624 1916 TSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEID---EERASLQKSISDTSALITQK 1974
Cdd:PRK11281   192 SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltARIQRLEHQLQLLQEAINSK 253
PRK11281 PRK11281
mechanosensitive channel MscK;
831-1201 3.73e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  831 ETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND------ 904
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLStlslrq 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  905 -ELRLKER--QLEQIQLELTKANEKAVQLQKNVEQtAQKA-EQSQQETlkthqEELKKMQDQLTDMKKQMETSQnqykdl 980
Cdd:PRK11281   126 lESRLAQTldQLQNAQNDLAEYNSQLVSLQTQPER-AQAAlYANSQRL-----QQIRNLLKGGKVGGKALRPSQ------ 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  981 QAKYEKETSEMITKHDadikgFKQNLLDAEEALKA-AQKKNDELetqAEELKKQAEQAKSLSSVLASarKEIELMSDKMR 1059
Cdd:PRK11281   194 RVLLQAEQALLNAQND-----LQRKSLEGNTQLQDlLQKQRDYL---TARIQRLEHQLQLLQEAINS--KRLTLSEKTVQ 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1060 DLISEKETLAQERNTLkLEKESLLSQHLemeSKILLVQQDR------EELWTKN--EELNSENKKILKQKEAAEAK---S 1128
Cdd:PRK11281   264 EAQSQDEAARIQANPL-VAQELEINLQL---SQRLLKATEKlntltqQNLRVKNwlDRLTQSERNIKEQISVLKGSlllS 339

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359624 1129 RQESTEKVALISekSKLLSEIETAQADL----LKITQENDALrSSESTLLQQLKELQANK--DAVDVACQKHIKEREEL 1201
Cdd:PRK11281   340 RILYQQQQALPS--ADLIEGLADRIADLrleqFEINQQRDAL-FQPDAYIDKLEAGHKSEvtDEVRDALLQLLDERREL 415
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1798-1938 3.77e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 3.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1798 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1877
Cdd:pfam06160  267 EIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGL----EKQLEELE 342

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624 1878 KEFEALKLAAAQKSQ--------------QLAALQEENVKLAEELGRSR-DEVTSHQKLEEERSVLNNQLLEMKKS 1938
Cdd:pfam06160  343 KRYDEIVERLEEKEVayselqeeleeileQLEEIEEEQEEFKESLQSLRkDELEAREKLDEFKLELREIKRLVEKS 418
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 830-1016 4.45e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  830 QETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLM--KMNDELR 907
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  908 LKERQLEQIQLELTKANEKAVQLQKNVEQtaqkaeqsqqetlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKE 987
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEE---------------LEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170       180
                   ....*....|....*....|....*....
gi 2024359624  988 TSEMITKHDADIKGFKQNLLDAEEALKAA 1016
Cdd:COG1579    158 LEELEAEREELAAKIPPELLALYERIRKR 186
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
823-1165 4.60e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 4.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  823 ENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKM 902
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  903 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 982
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEE-LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  983 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLI 1062
Cdd:COG4372    165 ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALEL 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1063 SEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEK 1142
Cdd:COG4372    245 EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324

                          330       340
                   ....*....|....*....|...
gi 2024359624 1143 SKLLSEIETAQADLLKITQENDA 1165
Cdd:COG4372    325 AKKLELALAILLAELADLLQLLL 347
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1798-1939 4.62e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1798 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1877
Cdd:PRK04778   286 EIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQL----EKQLESLE 361

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359624 1878 KEFEALKLAAAQKSQ---QLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEMKKSL 1939
Cdd:PRK04778   362 KQYDEITERIAEQEIaysELQEELEEILKQLEEIEKEQEKLSEMlQGLRKDELEAREKLERYRNKL 427
PLN02939 PLN02939
transferase, transferring glycosyl groups
 791-1158 4.74e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 4.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  791 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRamqeTINKLNQKEEQfAL-----MSSELEQLKSNLTVMETKLK 865
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEK----NILLLNQARLQ-ALedlekILTEKEALQGKINILEMRLS 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  866 EREEREQQLTEAKVKLEndiaeimkssgdssaqlmkmndelrLKERQLEQIQLELTK--ANEKAVQLQKNVEQTAQKAEQ 943
Cdd:PLN02939   181 ETDARIKLAAQEKIHVE-------------------------ILEEQLEKLRNELLIrgATEGLCVHSLSKELDVLKEEN 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  944 SqqeTLKTHQEELKKMQDQLTDMKKQMetsqnqykdlqAKYEKETSEMitkhDADIKGFKQNLLDAEEAL--------KA 1015
Cdd:PLN02939   236 M---LLKDDIQFLKAELIEVAETEERV-----------FKLEKERSLL----DASLRELESKFIVAQEDVsklsplqyDC 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1016 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD-----LISEKETLAQERntLKLEKESLLSQHLEME 1090
Cdd:PLN02939   298 WWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEanvskFSSYKVELLQQK--LKLLEERLQASDHEIH 375

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359624 1091 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSrqESTEKVALISEKSKLLSEIETAQADLLK 1158
Cdd:PLN02939   376 SYIQLYQESIKEFQDTLSKLKEESKKRSLEHPADDMPS--EFWSRILLLIDGWLLEKKISNNDAKLLR 441
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 428-1522 5.55e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 5.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  428 LLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMElerdlalrvkEVAELRGR---LESSKHIDDVDTSLSLL 504
Cdd:TIGR01612 1017 LYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIID----------EIEKEIGKnieLLNKEILEEAEINITNF 1086

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  505 QEIsslQEKM-----AAAGKE----HQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANK------ 569
Cdd:TIGR01612 1087 NEI---KEKLkhynfDDFGKEenikYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDvadkai 1163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  570 --ENSDVIELWKSKLESAIASHQQAMEELKVSFNkgvgaQTAEFAELKTQMEKVK---LDYENEMSNLKLKQ---ENEKS 641
Cdd:TIGR01612 1164 snDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLN-----EIAEIEKDKTSLEEVKginLSYGKNLGKLFLEKideEKKKS 1238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  642 QHLkeIEALKAKLlevteekeQTLENLKAKLESVEDQHLVEMEDT--LNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQ 719
Cdd:TIGR01612 1239 EHM--IKAMEAYI--------EDLDEIKEKSPEIENEMGIEMDIKaeMETFNISHDDDKDHHIISKKHDENISDIREKSL 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  720 QIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNL-ETEKVGGSSKVSNLTKELQGKEQKL-----LDLEKN 793
Cdd:TIGR01612 1309 KIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIyNILKLNKIKKIIDEVKEYTKEIEENnknikDELDKS 1388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  794 LSAVNQVKDSLEkeLQLLKEKFTSAVDGAEnaqraMQETINKLnqKEEQFALMSSEleqlkSNLTVMETKLKEREEREQQ 873
Cdd:TIGR01612 1389 EKLIKKIKDDIN--LEECKSKIESTLDDKD-----IDECIKKI--KELKNHILSEE-----SNIDTYFKNADENNENVLL 1454

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  874 LTEAKVKLENDIAEIMKSSGDSSAQLMKMN-DELRLKERQLEQIQlelTKANEKAVQLQKNVEQTAQKAEQSQQETLKTH 952
Cdd:TIGR01612 1455 LFKNIEMADNKSQHILKIKKDNATNDHDFNiNELKEHIDKSKGCK---DEADKNAKAIEKNKELFEQYKKDVTELLNKYS 1531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  953 QEELKKMQDQltdMKKQMETSQNQYKDLQAKY--EKETSEMITKhdaDIKGFKQNLLDAEEALKAAQKKNDELETQAEEL 1030
Cdd:TIGR01612 1532 ALAIKNKFAK---TKKDSEIIIKEIKDAHKKFilEAEKSEQKIK---EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENF 1605

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1031 KKQAEQAKSLSSVLASARKEIELMSDKMRDL-ISEKETLAQER----NTLKLEKESLLSQHLEMESKILLVQQDREELWT 1105
Cdd:TIGR01612 1606 ENKFLKISDIKKKINDCLKETESIEKKISSFsIDSQDTELKENgdnlNSLQEFLESLKDQKKNIEDKKKELDELDSEIEK 1685

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1106 KNEELNSENKK-----ILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAqaDLLKI----------TQENDALR--- 1167
Cdd:TIGR01612 1686 IEIDVDQHKKNyeigiIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTN--DLEGIdpnekleeynTEIGDIYEefi 1763

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1168 -------------SSESTLLQQLKELQANkdavdvACQKHIKEREELEHYQKLLE-----ENDRVI----KDKDDVIQRL 1225
Cdd:TIGR01612 1764 elyniiagcletvSKEPITYDEIKNTRIN------AQNEFLKIIEIEKKSKSYLDdieakEFDRIInhfkKKLDHVNDKF 1837

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1226 QSSYDDLARNQRELLQEVSILTAERDSAQEKDLdLKSTHIALKNEIDcllQTNRSLQSEKEMLLKSREELCVSLANTANE 1305
Cdd:TIGR01612 1838 TKEYSKINEGFDDISKSIENVKNSTDENLLFDI-LNKTKDAYAGIIG---KKYYSYKDEAEKIFINISKLANSINIQIQN 1913

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1306 NQALKLRKD---EMQTELETEREKLEKMTKDNMDLKASLSSLSN----FLEEMKSSREASNSEKihllQEALFASEQRLL 1378
Cdd:TIGR01612 1914 NSGIDLFDNiniAILSSLDSEKEDTLKFIPSPEKEPEIYTKIRDsydtLLDIFKKSQDLHKKEQ----DTLNIIFENQQL 1989

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1379 AEREELVNENKAVTEKlTKATADAVLAETAFT-EKINELN------------LE---KESVFSKSLQFEKHNEALLREKD 1442
Cdd:TIGR01612 1990 YEKIQASNELKDTLSD-LKYKKEKILNDVKLLlHKFDELNklscdsqnydtiLElskQDKIKEKIDNYEKEKEKFGIDFD 2068

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1443 --ELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKknLENQelIACRSDLSDLLKE 1520
Cdd:TIGR01612 2069 vkAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKI--IEDK--IIEKNDLIDKLIE 2144


                   ..
gi 2024359624 1521 AQ 1522
Cdd:TIGR01612 2145 MR 2146
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 921-1040 5.59e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.25  E-value: 5.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  921 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMkkqmetsQNQYKDLQAKYEKETsemitkhdadik 1000
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATA-------QKELANAQAQALQTA------------ 316

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2024359624 1001 gfKQNLLDAEEALKAAQKKNDELETQAEELK-KQAEQAKSL 1040
Cdd:TIGR04320  317 --QNNLATAQAALANAEARLAKAKEALANLNaDLAKKQAAL 355
PRK12704 PRK12704
phosphodiesterase; Provisional
 734-890 6.19e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 6.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  734 LQKANSEGKlEIQKlsEQLQAAEKQIQNL--ETEKvggssKVSNLTKELQGKEQKLLDLEKNlsavnqvkdsLEKELQLL 811
Cdd:PRK12704    44 LEEAKKEAE-AIKK--EALLEAKEEIHKLrnEFEK-----ELRERRNELQKLEKRLLQKEEN----------LDRKLELL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  812 KEKftsavdgaenaQRAMQETINKLNQKEEQFALMSSELEQLKSN-LTVME--TKLKEREEREQQLTEAKVKLENDIAEI 888
Cdd:PRK12704   106 EKR-----------EEELEKKEKELEQKQQELEKKEEELEELIEEqLQELEriSGLTAEEAKEILLEKVEEEARHEAAVL 174


                   ..
gi 2024359624  889 MK 890
Cdd:PRK12704   175 IK 176
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1573-2082 6.75e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.65  E-value: 6.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1573 EVENMKENLTVEKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIkEKMILY 1652
Cdd:pfam05557    6 ESKARLSQLQNEKKQMELEHKR---ARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQA-ELNRLK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1653 KETEQLASKIEQLKSDftslsvSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLhaewkslviinEEILKEK 1732
Cdd:pfam05557   82 KKYLEALNKKLNEKES------QLADAREVISCLKNELSELRRQIQRAELELQSTNSELEEL-----------QERLDLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1733 EKLSKEYYKLHEkvvalleqtdadfscrllvsegKHELLLEEMSNLALKLREIERlQAQTFMQKFEADKRAEEVLQTMEK 1812
Cdd:pfam05557  145 KAKASEAEQLRQ----------------------NLEKQQSSLAEAEQRIKELEF-EIQSQEQDSEIVKNSKSELARIPE 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1813 VTKEKDAIHQEKietlASLENSRQTNEKLQNELDMLKQnNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQK-- 1890
Cdd:pfam05557  202 LEKELERLREHN----KHLNENIENKLLLKEEVEDLKR-KLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlr 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1891 -----SQQLAALQEENVKLAEELG----RSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNT-------LRESTLKKEID 1954
Cdd:pfam05557  277 spedlSRRIEQLQQREIVLKEENSsltsSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKalvrrlqRRVLLLTKERD 356

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1955 EERASLQK-----SISDTSALITQKDEELEKLRNEITVLRGEnasaktLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 2029
Cdd:pfam05557  357 GYRAILESydkelTMSNYSPQLLERIEEAEDMTQKMQAHNEE------MEAQLSVAEEELGGYKQQAQTLERELQALRQQ 430

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024359624 2030 PLTVTSPSgdiaanllQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMC 2082
Cdd:pfam05557  431 ESLADPSY--------SKEEVDSLRRKLETLELERQRLREQKNELEMELERRC 475
PRK11281 PRK11281
mechanosensitive channel MscK;
978-1281 6.91e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 6.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  978 KDLQAKYEKETSemITKHDADIKGFKQNLLDAEEALKAAQKKNDELEtqaeELKKQAEQAKSLssvLASARKEIELMSDk 1057
Cdd:PRK11281    39 ADVQAQLDALNK--QKLLEAEDKLVQQDLEQTLALLDKIDRQKEETE----QLKQQLAQAPAK---LRQAQAELEALKD- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1058 mrdliSEKETLAQERNTLKLEkesllsqhlEMESKILLVQQDREELwtkNEELNSENKKILKQkeaaeaksrQESTEKV- 1136
Cdd:PRK11281   109 -----DNDEETRETLSTLSLR---------QLESRLAQTLDQLQNA---QNDLAEYNSQLVSL---------QTQPERAq 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1137 ALISEKSKLLSEIETaqadLLKITQEND-ALRSSESTLLQ------------QLKELQANKDAVDVACQKHIKEREE--- 1200
Cdd:PRK11281   163 AALYANSQRLQQIRN----LLKGGKVGGkALRPSQRVLLQaeqallnaqndlQRKSLEGNTQLQDLLQKQRDYLTARiqr 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1201 LEHYQKLLEE--NDRVIKDKDDVIQRLQSSyDDLARNQ--RELLQEVSILTAERD---SAQEKDLDLKSTHIALKNEIDC 1273
Cdd:PRK11281   239 LEHQLQLLQEaiNSKRLTLSEKTVQEAQSQ-DEAARIQanPLVAQELEINLQLSQrllKATEKLNTLTQQNLRVKNWLDR 317


                   ....*...
gi 2024359624 1274 LLQTNRSL 1281
Cdd:PRK11281   318 LTQSERNI 325
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1489-2106 8.20e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.50  E-value: 8.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1489 SIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRE---RTELQD 1565
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEiekEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1566 KCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEfltekelLVQEKEKSETKLEEVI 1645
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK-------AEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1646 KEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIIN 1725
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1726 EEILKEK------EKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ-----TFM 1794
Cdd:pfam02463  422 KEEKKEEleileeEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQkleerSQK 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1795 QKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE 1874
Cdd:pfam02463  502 ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLR 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1875 ELKKEFEALKLAAAQKS--------QQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRE 1946
Cdd:pfam02463  582 LLIPKLKLPLKSIAVLEidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1947 STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAK 2026
Cdd:pfam02463  662 SEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 2027 S------EQPLTVTSPSGDIAANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEE 2100
Cdd:pfam02463  742 KqkideeEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQ 821


                   ....*.
gi 2024359624 2101 EGLSKK 2106
Cdd:pfam02463  822 LLIEQE 827
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1029-1265 8.45e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 8.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1029 ELKKQAEQAKSLSSVLASARKeIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEmeSKILLVQQDREELWTKNE 1108
Cdd:PRK05771    34 EDLKEELSNERLRKLRSLLTK-LSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVE--EELEKIEKEIKELEEEIS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1109 ELNSENKKILKQKEAAE----------AKSRQESTE-KVALISEKSKLLSEIETAQADLLKITQEND-------ALRSSE 1170
Cdd:PRK05771   111 ELENEIKELEQEIERLEpwgnfdldlsLLLGFKYVSvFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvVLKELS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1171 STLLQQLKELQAnkDAVDVACQKHIKEReeLEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELlqevsiLTAER 1250
Cdd:PRK05771   191 DEVEEELKKLGF--ERLELEEEGTPSEL--IREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIEL 260

                          250
                   ....*....|....*
gi 2024359624 1251 DSAQEKDLDLKSTHI 1265
Cdd:PRK05771   261 ERAEALSKFLKTDKT 275
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 471-700 9.12e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  471 ERDLALRVKEVAELRGRLesSKHIDDVDTSLSLLQEISSLQEKMaaagkehqrEMSSLKEKFESSEEALRKEIKTLSASN 550
Cdd:PRK05771    38 EELSNERLRKLRSLLTKL--SEALDKLRSYLPKLNPLREEKKKV---------SVKSLEELIKDVEEELEKIEKEIKELE 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  551 ERMgKENESLKTKLDHANKE-------NSDVIELWKSKLESAIAS--HQQAMEELKVSFNKGVgAQTAEFAE-------- 613
Cdd:PRK05771   107 EEI-SELENEIKELEQEIERlepwgnfDLDLSLLLGFKYVSVFVGtvPEDKLEELKLESDVEN-VEYISTDKgyvyvvvv 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  614 -LKTQMEKV-KLDYENEMSNLKLKQENEKSQhlkEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQ 691
Cdd:PRK05771   185 vLKELSDEVeEELKKLGFERLELEEEGTPSE---LIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELE 261


                   ....*....
gi 2024359624  692 EAEIKVKEL 700
Cdd:PRK05771   262 RAEALSKFL 270
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 736-1073 9.12e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.99  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  736 KANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKElqgKEQKLLDLEKNLSAVNQvkdSLEKELQLLKEKF 815
Cdd:PLN03229   422 KKREAVKTPVRELEGEVEKLKEQILKAKESSSKPSELALNEMIE---KLKKEIDLEYTEAVIAM---GLQERLENLREEF 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  816 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmeTKLKEReEREQQLTEAKVKLENDIAEIMKssgds 895
Cdd:PLN03229   496 SKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSLKYKL----DMLNEF-SRAKALSEKKSKAEKLKAEINK----- 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  896 saQLMKMNDELRLKERqLEQIQLELTKAN-EKAVQLQKNVEQTAQKAEQSQQETLKthqEELKKMQDQLTDM-KKQMETS 973
Cdd:PLN03229   566 --KFKEVMDRPEIKEK-MEALKAEVASSGaSSGDELDDDLKEKVEKMKKEIELELA---GVLKSMGLEVIGVtKKNKDTA 639

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  974 QNQ-YKDLQAKYEK---ETSEMITK--HDADIKGfKQNLLDAEEAlKAAQKKNDELETQAEELKKQAEQakSLSSVLASA 1047
Cdd:PLN03229   640 EQTpPPNLQEKIESlneEINKKIERviRSSDLKS-KIELLKLEVA-KASKTPDVTEKEKIEALEQQIKQ--KIAEALNSS 715

                          330       340
                   ....*....|....*....|....*.
gi 2024359624 1048 rkEIELMSDKMRDLISEKETLAQERN 1073
Cdd:PLN03229   716 --ELKEKFEELEAELAAARETAAESN 739
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 743-917 9.81e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 9.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  743 LEIQK---LSEQL-QAAEKQIQNlETEKVGGS-SKVSNLTKELqgkEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 817
Cdd:PRK00409   491 FEIAKrlgLPENIiEEAKKLIGE-DKEKLNELiASLEELEREL---EQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDK 566

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624  818 AVDGAE--------NAQRAMQETINKLN--QKEEQFALMSSELE----QLKSNLTVMETKLKEREEREQQLT---EAKVK 880
Cdd:PRK00409   567 LLEEAEkeaqqaikEAKKEADEIIKELRqlQKGGYASVKAHELIearkRLNKANEKKEKKKKKQKEKQEELKvgdEVKYL 646

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2024359624  881 LENDIAEIMKSSGDSSAQ----LMKMndelRLKERQLEQIQ 917
Cdd:PRK00409   647 SLGQKGEVLSIPDDKEAIvqagIMKM----KVPLSDLEKIQ 683
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 1025-1284 9.84e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 40.78  E-value: 9.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1025 TQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLisekETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELW 1104
Cdd:pfam05667  301 THTEKLQFTNEAPAATSSPPTKVETEEELQQQREEEL----EELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELK 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1105 TKNEELNSENKkiLKQKEAAEAKSRQESTEKvalisekskLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANK 1184
Cdd:pfam05667  377 EQNEELEKQYK--VKKKTLDLLPDAEENIAK---------LQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKSNK 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359624 1185 DAvdvACQKHIKEREEL-EHYQKLLEEndrvIKDKDDVIQRLQSSYDDLArnqrellQEVSiltaeRDSAQEKDLDLKST 1263
Cdd:pfam05667  446 ED---ESQRKLEEIKELrEKIKEVAEE----AKQKEELYKQLVAEYERLP-------KDVS-----RSAYTRRILEIVKN 506

                          250       260
                   ....*....|....*....|.
gi 2024359624 1264 HIALKNEIDCLLQTNRSLQSE 1284
Cdd:pfam05667  507 IKKQKEEITKILSDTKSLQKE 527
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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