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Conserved domains on  [gi|2024359632|ref|XP_015130677|]
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CAP-Gly domain-containing linker protein 1 isoform X15 [Gallus gallus]

Protein Classification

CAP-Gly domain-containing linker protein( domain architecture ID 13652563)

CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth

Gene Ontology:  GO:0031122|GO:0008017
PubMed:  15928712

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 7.98e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 7.98e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.16e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.16e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 655-1453 4.21e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 4.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  655 AEFAELKTQMEKVKLDYENEMSNLKLKQEneksqhlkEIEALKAKLLEVTEEKEQ---TLENLKAKLESVEdqhlVEMED 731
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEE--------KLEELRLEVSELEEEIEElqkELYALANEISRLE----QQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  732 TLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEE 811
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  812 QFALMSSELEQLKSNLTVMETKLKEREEREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQI 886
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  887 QLELTKANEKAVQLQKNVEQTAQKAE--QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsem 961
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI--- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  962 itkhDADIKGFKQNLL--DAEEALKA--AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIE 1022
Cdd:TIGR02168  540 ----EAALGGRLQAVVveNLNAAKKAiaFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1023 LMSDKMRDLISEKETLAQERNTLKLEKE----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKK 1086
Cdd:TIGR02168  616 KALSYLLGGVLVVDDLDNALELAKKLRPgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1087 ILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhik 1166
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE---------- 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1167 EREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQ 1246
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1247 TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE 1326
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1327 ASNSEKIHL------LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfsks 1397
Cdd:TIGR02168  926 QLELRLEGLevridnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE----- 993

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1398 lQFEKHNEallrEKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQEN 1453
Cdd:TIGR02168  994 -EYEELKE----RYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1279-1995 2.37e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.37e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1350
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1351 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1430
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1431 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1510
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1511 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1590
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1591 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1670
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1671 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1733
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1734 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1779
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1780 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1859
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1860 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1939
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1940 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 1995
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-930 4.55e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.69  E-value: 4.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  427 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENTQTKLE------HARIKELeqSLLFEKTK--------- 491
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNLDDQLQklladlHKREKEL--SLEKEQNKrlwdrdtgn 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  492 ---ADKLQRELEDtrvatvseksRIMELERDLALRVKEVAELRGRLEsskhiddvdtslsllQEISSLQEKmaaagKEHQ 568
Cdd:pfam15921  411 sitIDHLRRELDD----------RNMEVQRLEALLKAMKSECQGQME---------------RQMAAIQGK-----NESL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  569 REMSSLKEKFESSEEALRKEIKTLSAsnERMGKEN-ESLKTKLDHANKENSDVIELWKS---KLESAIASHQQAMEELKV 644
Cdd:pfam15921  461 EKVSSLTAQLESTKEMLRKVVEELTA--KKMTLESsERTVSDLTASLQEKERAIEATNAeitKLRSRVDLKLQELQHLKN 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  645 SFNKGVGAQTaEFAELKTQM---EKVKLDYENEMSNL-KLKQENEKSQHLKEIEalKAKLLEVTEEKEQTLENLKAkLES 720
Cdd:pfam15921  539 EGDHLRNVQT-ECEALKLQMaekDKVIEILRQQIENMtQLVGQHGRTAGAMQVE--KAQLEKEINDRRLELQEFKI-LKD 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  721 VEDQHLVEMEDTLNKLQEAEIKVSNLTKEL--------QGKEQKLLDLEKNLSAVNqvkdSLEKELQLLKEKFTSAVDGA 792
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERlravkdikQERDQLLNEVKTSRNELN----SLSEDYEVLKRNFRNKSEEM 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  793 E-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEA 847
Cdd:pfam15921  691 EtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  848 KVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELK 927
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846


                   ...
gi 2024359632  928 KMQ 930
Cdd:pfam15921  847 ELQ 849
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2119-2135 7.60e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.60e-08
                           10
                   ....*....|....*..
gi 2024359632 2119 RPYCDTCEMFGHWTADC 2135
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2079-2096 5.54e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.54e-04
                           10
                   ....*....|....*...
gi 2024359632 2079 RLFCDICGCFDlHDTEDC 2096
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 7.98e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 7.98e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.16e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.16e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.57e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.57e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.83e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.83e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 655-1453 4.21e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 4.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  655 AEFAELKTQMEKVKLDYENEMSNLKLKQEneksqhlkEIEALKAKLLEVTEEKEQ---TLENLKAKLESVEdqhlVEMED 731
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEE--------KLEELRLEVSELEEEIEElqkELYALANEISRLE----QQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  732 TLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEE 811
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  812 QFALMSSELEQLKSNLTVMETKLKEREEREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQI 886
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  887 QLELTKANEKAVQLQKNVEQTAQKAE--QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsem 961
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI--- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  962 itkhDADIKGFKQNLL--DAEEALKA--AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIE 1022
Cdd:TIGR02168  540 ----EAALGGRLQAVVveNLNAAKKAiaFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1023 LMSDKMRDLISEKETLAQERNTLKLEKE----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKK 1086
Cdd:TIGR02168  616 KALSYLLGGVLVVDDLDNALELAKKLRPgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1087 ILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhik 1166
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE---------- 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1167 EREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQ 1246
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1247 TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE 1326
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1327 ASNSEKIHL------LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfsks 1397
Cdd:TIGR02168  926 QLELRLEGLevridnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE----- 993

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1398 lQFEKHNEallrEKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQEN 1453
Cdd:TIGR02168  994 -EYEELKE----RYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNEN 1044
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 754-1438 6.68e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 6.68e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  754 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRAmqetiNKLNQKEEQF--ALMSSELEQLKSNLTVME 831
Cdd:COG1196    178 ERKLEATEENLERLEDILGELERQLEPLERQ-------AEKAERY-----RELKEELKELeaELLLLKLRELEAELEELE 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  832 TKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKA 911
Cdd:COG1196    246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-LEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  912 EQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKhDADIKGFKQNLLDAEEALKAAQKKND 991
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA-EEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  992 ELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDRE 1071
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1072 ELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQ 1151
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1152 ANKDAVDVAcQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLK 1231
Cdd:COG1196    558 VAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1232 STHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASL 1311
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1312 SSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNEnKAVTEKLTKATAD-AVLaetaftEKINELNLEk 1390
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-EELERELERLEREiEAL------GPVNLLAIE- 788

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359632 1391 esvfskslQFEkhneALLREKDELERKYSELLDEKKSLENAFSDMKRE 1438
Cdd:COG1196    789 --------EYE----ELEERYDFLSEQREDLEEARETLEEAIEEIDRE 824
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1279-1995 2.37e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.37e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1350
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1351 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1430
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1431 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1510
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1511 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1590
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1591 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1670
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1671 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1733
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1734 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1779
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1780 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1859
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1860 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1939
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1940 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 1995
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
PTZ00121 PTZ00121
MAEBL; Provisional
 345-1128 1.99e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.80  E-value: 1.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  345 ARKISGTTALQEALKE-----KQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvRDGHDRHVLEMEAKMDQLRamvE 419
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDaeeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAK---K 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  420 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKELEQSLlfEKTKADKLQREL 499
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAE--EKAEAAEKKKEE 1375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  500 EDTRVATV----SEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGK--------EH 567
Cdd:PTZ00121  1376 AKKKADAAkkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadeakkkaEE 1455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  568 QREMSSLKEKFESSEEALRKEIKTLSASN-ERMGKENESLKTKLDHANKENsdviELWKSKLESAIASHQQAMEELKvsf 646
Cdd:PTZ00121  1456 AKKAEEAKKKAEEAKKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAA----EAKKKADEAKKAEEAKKADEAK--- 1528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  647 nKGVGAQTAEfaELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHL 726
Cdd:PTZ00121  1529 -KAEEAKKAD--EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  727 VEMEDTLNKLQEAEIKVSNLTKElqgkeqklldleknlsavnqvkDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK- 805
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKA----------------------EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKa 1663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  806 --LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIaeimkssgdssaqlmkmndelrlkeRQL 883
Cdd:PTZ00121  1664 aeEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------------------------KKA 1718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  884 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMIT 963
Cdd:PTZ00121  1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD----EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  964 KHDADIKGFKQNLLDAEEALKAAQKK-NDELETQAEELKkqaEQAKSLSSVLASArKEIELMSDKMRDLISEKETLAQER 1042
Cdd:PTZ00121  1795 EVDKKIKDIFDNFANIIEGGKEGNLViNDSKEMEDSAIK---EVADSKNMQLEEA-DAFEKHKFNKNNENGEDGNKEADF 1870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1043 NTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSR--QESTEKVALISEKSKLLSEIE 1120
Cdd:PTZ00121  1871 NKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRdaEETREEIIKISKKDMCINDFS 1950


                   ....*...
gi 2024359632 1121 TAQADLLK 1128
Cdd:PTZ00121  1951 SKFCDYMK 1958
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-930 4.55e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.69  E-value: 4.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  427 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENTQTKLE------HARIKELeqSLLFEKTK--------- 491
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNLDDQLQklladlHKREKEL--SLEKEQNKrlwdrdtgn 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  492 ---ADKLQRELEDtrvatvseksRIMELERDLALRVKEVAELRGRLEsskhiddvdtslsllQEISSLQEKmaaagKEHQ 568
Cdd:pfam15921  411 sitIDHLRRELDD----------RNMEVQRLEALLKAMKSECQGQME---------------RQMAAIQGK-----NESL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  569 REMSSLKEKFESSEEALRKEIKTLSAsnERMGKEN-ESLKTKLDHANKENSDVIELWKS---KLESAIASHQQAMEELKV 644
Cdd:pfam15921  461 EKVSSLTAQLESTKEMLRKVVEELTA--KKMTLESsERTVSDLTASLQEKERAIEATNAeitKLRSRVDLKLQELQHLKN 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  645 SFNKGVGAQTaEFAELKTQM---EKVKLDYENEMSNL-KLKQENEKSQHLKEIEalKAKLLEVTEEKEQTLENLKAkLES 720
Cdd:pfam15921  539 EGDHLRNVQT-ECEALKLQMaekDKVIEILRQQIENMtQLVGQHGRTAGAMQVE--KAQLEKEINDRRLELQEFKI-LKD 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  721 VEDQHLVEMEDTLNKLQEAEIKVSNLTKEL--------QGKEQKLLDLEKNLSAVNqvkdSLEKELQLLKEKFTSAVDGA 792
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERlravkdikQERDQLLNEVKTSRNELN----SLSEDYEVLKRNFRNKSEEM 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  793 E-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEA 847
Cdd:pfam15921  691 EtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  848 KVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELK 927
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846


                   ...
gi 2024359632  928 KMQ 930
Cdd:pfam15921  847 ELQ 849
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.91e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 70.87  E-value: 5.91e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 408-1170 3.37e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.99  E-value: 3.37e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  408 EAKMDQLRAMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgDLERKRQ--ISEDPENTQTKLEHARIKEleQSL 485
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----ELHEKQKfyLRQSVIDLQTKLQEMQMER--DAM 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  486 LFEKTKADKLQRELEDTRVATVSEKSRIMELERD-LALRVKEVAELRGRLESSKHIddvdtslslLQEISS-LQEKMAAA 563
Cdd:pfam15921  130 ADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDmLEDSNTQIEQLRKMMLSHEGV---------LQEIRSiLVDFEEAS 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  564 GKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwksklesAIASHQQAMEELK 643
Cdd:pfam15921  201 GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIEL-------LLQQHQDRIEQLI 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  644 VSFNKGVGAQTAEFAELKTQMEKVkldyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVED 723
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSI----QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  724 QHLV---EMEDTLNKLQEAEIKVSNLTKELQG------KEQKLLDLEKN----------------------LSAVNQVKD 772
Cdd:pfam15921  350 QLVLansELTEARTERDQFSQESGNLDDQLQKlladlhKREKELSLEKEqnkrlwdrdtgnsitidhlrreLDDRNMEVQ 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  773 SLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT----EAK 848
Cdd:pfam15921  430 RLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTaslqEKE 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  849 VKLENDIAEIMKSSGDSSAQLMKMN------DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsQQETLKTH 922
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDLKLQELQhlknegDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-HGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  923 QEELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEMITKHdADIKGFKQNLLDA-EEALKAA----QKKN---DELE 994
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRELEARV-SDLELEKVKLVNAgSERLRAVkdikQERDqllNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  995 TQAEELKKQAEQAKSLSSVLASARKEIELMSDKMR-DLISEKETLAQERNTLKlekesllSQHLEMESKILLVQQDREEL 1073
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQTRNTLK-------SMEGSDGHAMKVAMGMQKQI 736

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1074 WTKNEELNSENKKILKQKEAAEAKSRqestEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQAN 1153
Cdd:pfam15921  737 TAKRGQIDALQSKIQFLEEAMTNANK----EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVA 812

                          810       820
                   ....*....|....*....|
gi 2024359632 1154 KDAVDVA---CQKHIKEREE 1170
Cdd:pfam15921  813 LDKASLQfaeCQDIIQRQEQ 832
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1699-1998 7.91e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1699 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1778
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1779 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1858
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1859 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1938
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1939 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 1998
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1279-1957 9.21e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 9.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1355
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1356 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1430
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1431 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1508
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1509 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1569
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1570 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1640
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1641 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1717
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1718 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1793
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1794 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1861
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1862 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1922
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359632 1923 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1957
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.27e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.27e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1580-1994 5.05e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 5.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1580 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1659
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1660 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1739
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1740 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1819
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1820 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1894
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1895 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 1974
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359632 1975 LESDKLKLEEKVKNLEQKLK 1994
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 376-739 8.62e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 8.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  376 RAEVAKATSHVGEIEQELALVRDGHDrhvlEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGD 455
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  456 LERKRQisedpentqtkLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLE 535
Cdd:TIGR02168  759 LEAEIE-----------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  536 SS-KHIDDVDTSLS-LLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHA 613
Cdd:TIGR02168  828 SLeRRIAATERRLEdLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  614 NKENSDVIELwKSKLESAIASHQQAMEELKVsfnkgvgaqtaEFAELKTQ-MEKVKLDYEN--EMSNLKLKQENEKSQHL 690
Cdd:TIGR02168  907 ESKRSELRRE-LEELREKLAQLELRLEGLEV-----------RIDNLQERlSEEYSLTLEEaeALENKIEDDEEEARRRL 974

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632  691 KEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEA 739
Cdd:TIGR02168  975 KRLENKIKELGPVNLAAIEEYEELKERYDFLTAQK-EDLTEAKETLEEA 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 352-857 1.01e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  352 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQ 431
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  432 LEEEKRKVEDLQFRVEEESitkGDLERKRQISEDPENTQTKLEhARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKS 511
Cdd:COG1196    360 LAEAEEALLEAEAELAEAE---EELEELAEELLEALRAAAELA-AQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  512 RIMELERDLALRVKEVAElrgrlesskhiddvdtslsLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKT 591
Cdd:COG1196    436 EEEEEEEALEEAAEEEAE-------------------LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  592 LSASNERMGKENESLKTKLDHANKENS---DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVK 668
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRAT 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  669 LDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVsnLTK 748
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLRE--VTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  749 ELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLT 828
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500
                   ....*....|....*....|....*....
gi 2024359632  829 VMETKLKEREEREQQLTEAKVKLENDIAE 857
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPP 760
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
353-952 2.89e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE--------ELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  433 EEEKRKVEDLQfrvEEESITKGDLERKRQISEDPEntqtklehARIKELEqsllfekTKADKLQRELEDTRV---ATVSE 509
Cdd:PRK02224   282 RDLRERLEELE---EERDDLLAEAGLDDADAEAVE--------ARREELE-------DRDEELRDRLEECRVaaqAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  510 KSRIMELERDLALRVKEVAELRGRLESskhiddvdtslsllqEISSLQEKMaaagkehqremsslkEKFESSEEALRKEI 589
Cdd:PRK02224   344 AESLREDADDLEERAEELREEAAELES---------------ELEEAREAV---------------EDRREEIEELEEEI 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  590 KTLSASNERMGKENESLKTKLDHANKENSDVIELWKSkLESAIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkl 669
Cdd:PRK02224   394 EELRERFGDAPVDLGNAEDFLEELREERDELREREAE-LEATLRTARERVEEAEALLEAGKCPECG-------------- 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  670 dyenemsnlklkQENEKSQHLKEIEALKAKLLEVTEEKEQ---TLENLKAKLESVEDqhLVEMEDTLNKLQEaeiKVSNL 746
Cdd:PRK02224   459 ------------QPVEGSPHVETIEEDRERVEELEAELEDleeEVEEVEERLERAED--LVEAEDRIERLEE---RREDL 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  747 TKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQllkEKFTSAVDGAENAQRAmQETINKLNQKEEQFALMSSELEQLKSN 826
Cdd:PRK02224   522 EELIAERRETIEEKRERAEELRERAAELEAEAE---EKREAAAEAEEEAEEA-REEVAELNSKLAELKERIESLERIRTL 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  827 LTVMETKLKEREEREQQLtEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQ---------LEQIQLELTKANEKA 897
Cdd:PRK02224   598 LAAIADAEDEIERLREKR-EALAELNDERRERLAEKRERKRELEAEFDEARIEEARedkeraeeyLEQVEEKLDELREER 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  898 VQLQKNVeqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 952
Cdd:PRK02224   677 DDLQAEI--GAVENELEELEELRERREALENRVEALEALYDEAEELESMYGDLRA 729
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2119-2135 7.60e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.60e-08
                           10
                   ....*....|....*..
gi 2024359632 2119 RPYCDTCEMFGHWTADC 2135
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2079-2096 5.54e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.54e-04
                           10
                   ....*....|....*...
gi 2024359632 2079 RLFCDICGCFDlHDTEDC 2096
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 749-965 3.07e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 42.25  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  749 ELQGK-EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQ 822
Cdd:cd22654    101 KLQSQlQTIQNSMEQTSSNLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEV 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  823 LKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQK 902
Cdd:cd22654    181 GDGSINIGKQVFTITITTATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTL 257

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632  903 NVEQTAQKAE--QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 965
Cdd:cd22654    258 VEDQVNGFTEliKRQIATLENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 7.98e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 7.98e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.16e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.16e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.57e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.57e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.83e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.83e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 655-1453 4.21e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.83  E-value: 4.21e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  655 AEFAELKTQMEKVKLDYENEMSNLKLKQEneksqhlkEIEALKAKLLEVTEEKEQ---TLENLKAKLESVEdqhlVEMED 731
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEE--------KLEELRLEVSELEEEIEElqkELYALANEISRLE----QQKQI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  732 TLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEE 811
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  812 QFALMSSELEQLKSNLTVMETKLKEREEREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQI 886
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  887 QLELTKANEKAVQLQKNVEQTAQKAE--QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsem 961
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI--- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  962 itkhDADIKGFKQNLL--DAEEALKA--AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIE 1022
Cdd:TIGR02168  540 ----EAALGGRLQAVVveNLNAAKKAiaFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1023 LMSDKMRDLISEKETLAQERNTLKLEKE----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKK 1086
Cdd:TIGR02168  616 KALSYLLGGVLVVDDLDNALELAKKLRPgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1087 ILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhik 1166
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE---------- 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1167 EREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQ 1246
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1247 TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE 1326
Cdd:TIGR02168  846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1327 ASNSEKIHL------LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfsks 1397
Cdd:TIGR02168  926 QLELRLEGLevridnLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE----- 993

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1398 lQFEKHNEallrEKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQEN 1453
Cdd:TIGR02168  994 -EYEELKE----RYDFLTAQKEDLTEAKETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 754-1635 2.71e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.52  E-value: 2.71e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  754 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRamqetinklnqkeeqFALMSSELEQLKSNLTVMEtk 833
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQ-------AEKAER---------------YKELKAELRELELALLVLR-- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  834 LKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKaeq 913
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEEL--------------TAELQELEEKLEELRLEVSELEEEIEELQKELYALANE--- 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  914 sqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDEL 993
Cdd:TIGR02168  297 --ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL----EEKLEELKEELESLEAELEELEAELEEL 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  994 ETQAEELKKQAEQAKS----LSSVLASARKEIELMSDKMRDLISEKETLAQERNTlkLEKESLLSQHLEMESKILLVQQD 1069
Cdd:TIGR02168  371 ESRLEELEEQLETLRSkvaqLELQIASLNNEIERLEARLERLEDRRERLQQEIEE--LLKKLEEAELKELQAELEELEEE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1070 REELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS---KLLSEIETAQADLLKITQENDALRSSESTLLQQ 1146
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDsleRLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1147 LKELQANKDAVDVACQKHIkereelehyQKLLEENDRVIKD-----KDDVIQRL------QSSYDDLARNQRELLQEVsi 1215
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRL---------QAVVVENLNAAKKaiaflKQNELGRVtflpldSIKGTEIQGNDREILKNI-- 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1216 ltaerDSAQEKDLDLKSTHIALKNEIDCLLQTNR---SLQSEKEMLLKSR-EELCVSLANT-------------ANENQA 1278
Cdd:TIGR02168  598 -----EGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKLRpGYRIVTLDGDlvrpggvitggsaKTNSSI 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKdemqtELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAEREELVNEN 1358
Cdd:TIGR02168  673 LERRR-----EIEELEEKIEELEEKIAELEKALAELRKELEELE--------EELEQLRKELEELSRQISALRKDLARLE 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1359 KAVtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1438
Cdd:TIGR02168  740 AEV-EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1439 QELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1518
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1519 CSSDIEILNRERTELQDKCQKLTGEVENMKENLTV------EKKARILDKESFLLERM-ELQNNIGF----LEKEVEEMR 1587
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGlevridNLQERLSEEYSLTLEEAeALENKIEDdeeeARRRLKRLE 978

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359632 1588 EKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQL 1635
Cdd:TIGR02168  979 NKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 679-1504 1.77e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 1.77e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  679 KLKQENEKSQHLKEI-EALKAKLLEVT----EEKEQTLENLKAKLESVEDQHlvemEDTLNKLQEAEIKVSNLTKELQGK 753
Cdd:TIGR02168  204 SLERQAEKAERYKELkAELRELELALLvlrlEELREELEELQEELKEAEEEL----EELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  754 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETK 833
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  834 LKEREEREQQLTEAKVKLEndiaeimkssgdssAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQ 913
Cdd:TIGR02168  360 LEELEAELEELESRLEELE--------------EQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  914 SQQETLKThqeELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIKGFKQNLLDAEEALKAAQKKNDEL 993
Cdd:TIGR02168  426 LLKKLEEA---ELKELQAELEELEEELEELQEELERLEEALEELREE-LEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  994 ETQAEELKKQAEQAKSLSSVLASARKEIE-----------LMSDKMRDLISEKETLAqerntlkLEKESLLSQHLEMESK 1062
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISvdegyeaaieaALGGRLQAVVVENLNAA-------KKAIAFLKQNELGRVT 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1063 ILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLK-------ITQENDA 1135
Cdd:TIGR02168  575 FLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrpgyriVTLDGDL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1136 LRSS----------ESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQssyddlaRN 1205
Cdd:TIGR02168  655 VRPGgvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS-------RQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1206 QRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDE 1285
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1286 MQTELETEREKLEKmtkdnmdlkaslsslsnfleemKSSREASNSEKIHLLQEALFASEQRLLAEREELvnenkavtEKL 1365
Cdd:TIGR02168  808 LRAELTLLNEEAAN----------------------LRERLESLERRIAATERRLEDLEEQIEELSEDI--------ESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1366 TKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQEldfsa 1445
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----- 932

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632 1446 kRLLVQENTTlkysIEALEEELkkkNLENQELIACRSDLSDLLKEAQDARRTLENELAA 1504
Cdd:TIGR02168  933 -GLEVRIDNL----QERLSEEY---SLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 403-1205 1.97e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 1.97e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  403 HVLEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESitkgdlERKRQISEDPENTQtklehARIKELE 482
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELE------EEIEELQKELYALA-----NEISRLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  483 QSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKhiDDVDTSLSLLQEISSLQEKMAA 562
Cdd:TIGR02168  302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE--AELEELEAELEELESRLEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  563 AGKEHQREMSSLKEKFESSE---EALRKEIKTLSASNERMGKENESLKTKLDHANKE----NSDVIELWKSKLESAIASH 635
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNneiERLEARLERLEDRRERLQQEIEELLKKLEEAELKelqaELEELEEELEELQEELERL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  636 QQAMEELKVSFNKGVGAQTA---EFAELKTQMEKVKLDYENEMSNLKLKQENEKSQH-LKEIEALKAKLLEVTEEKEQTL 711
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSgLSGILGVLSELISVDEGYEAAI 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  712 EN-LKAKLESVED----------QHLVE--------MEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQ--- 769
Cdd:TIGR02168  540 EAaLGGRLQAVVVenlnaakkaiAFLKQnelgrvtfLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKals 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  770 -------VKDSLEKELQLLKEK------FT----------SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSN 826
Cdd:TIGR02168  620 yllggvlVVDDLDNALELAKKLrpgyriVTldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  827 LTVMETKLkereereQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ 906
Cdd:TIGR02168  700 LAELRKEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  907 TaqkaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfKQNLLDAEEALKAA 986
Cdd:TIGR02168  773 A--------EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL---------------NEEAANLRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  987 QKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESK 1062
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSedieSLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1063 ILLVQQDREELWTKNEELNsENKKILKQKEA--AEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSE 1140
Cdd:TIGR02168  910 RSELRRELEELREKLAQLE-LRLEGLEVRIDnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVN 988

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1141 STLLQQLKELQANKDAVDvacqkhiKEREELEHYQKLLEEndrVIKDKDDVI-QRLQSSYDDLARN 1205
Cdd:TIGR02168  989 LAAIEEYEELKERYDFLT-------AQKEDLTEAKETLEE---AIEEIDREArERFKDTFDQVNEN 1044
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 754-1438 6.68e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 6.68e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  754 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRAmqetiNKLNQKEEQF--ALMSSELEQLKSNLTVME 831
Cdd:COG1196    178 ERKLEATEENLERLEDILGELERQLEPLERQ-------AEKAERY-----RELKEELKELeaELLLLKLRELEAELEELE 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  832 TKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKA 911
Cdd:COG1196    246 AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEE-LEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  912 EQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKhDADIKGFKQNLLDAEEALKAAQKKND 991
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA-EEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  992 ELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDRE 1071
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1072 ELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQ 1151
Cdd:COG1196    478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1152 ANKDAVDVAcQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLK 1231
Cdd:COG1196    558 VAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1232 STHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASL 1311
Cdd:COG1196    637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1312 SSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNEnKAVTEKLTKATAD-AVLaetaftEKINELNLEk 1390
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-EELERELERLEREiEAL------GPVNLLAIE- 788

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359632 1391 esvfskslQFEkhneALLREKDELERKYSELLDEKKSLENAFSDMKRE 1438
Cdd:COG1196    789 --------EYE----ELEERYDFLSEQREDLEEARETLEEAIEEIDRE 824
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 408-1321 1.11e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 1.11e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  408 EAKMDQLRAMVEAA------DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKEL 481
Cdd:TIGR02168  151 EAKPEERRAIFEEAagiskyKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  482 EQSLLFEKTKADKLQRELEDTRvatvsekSRIMELERDLALRVKEVAELRGrlesskhiddvdtslsllqEISSLQEKMA 561
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAE-------EELEELTAELQELEEKLEELRL-------------------EVSELEEEIE 284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  562 AAGKEHQrEMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKEnsdvIELWKSKLESAIASHQQAMEE 641
Cdd:TIGR02168  285 ELQKELY-ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE----LAELEEKLEELKEELESLEAE 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  642 LKvsfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHlKEIEALKAKLLEVTEEKEQTLENLKAKLESV 721
Cdd:TIGR02168  360 LE--------ELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-NEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  722 EDQHLVEMEDTLNKLQEAEIKvsnLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQ---RA 798
Cdd:TIGR02168  431 EEAELKELQAELEELEEELEE---LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsEG 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  799 MQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLkerEEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDelrL 878
Cdd:TIGR02168  508 VKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAL---GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDS---I 581

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  879 KERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQ---------ETLKTHQEELKKMQDQLTDMKKQMET-----SQ 944
Cdd:TIGR02168  582 KGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRIVTLDGDLvrpggVI 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  945 NQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQA----KSLSSVLASARKE 1020
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELsrqiSALRKDLARLEAE 741

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1021 IELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELwtkneelNSENKKILKQKEAAEAKSRQ 1100
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL-------KEELKALREALDELRAELTL 814

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1101 ESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDavdvacqkhiKEREELEHYQKLLEE 1180
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE----------ELESELEALLNERAS 884

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1181 NDRVIKdkddviqRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS-EKEMLL 1259
Cdd:TIGR02168  885 LEEALA-------LLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSlTLEEAE 957

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632 1260 KSREELCVSLANTANENQALKLRKDEM-------QTELETEREKLEKMTKDNMDLKASLSSLSNFLEEM 1321
Cdd:TIGR02168  958 ALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1279-1995 2.37e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.37e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1350
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1351 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1430
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1431 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1510
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1511 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1590
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1591 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1670
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1671 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1733
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1734 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1779
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1780 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1859
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1860 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1939
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1940 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 1995
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 832-1709 9.30e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 9.30e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  832 TKLKER-EEREQQLTEAKVKLE--NDIAEIMKSSGDS-SAQLMKMNDELRLKErQLEQIQLELTKAneKAVQLQKNVEQT 907
Cdd:TIGR02168  168 SKYKERrKETERKLERTRENLDrlEDILNELERQLKSlERQAEKAERYKELKA-ELRELELALLVL--RLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  908 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSE------MITKHDADIKGFKQNLLDAEE 981
Cdd:TIGR02168  245 QEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrleqQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  982 ALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1057
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1058 EMESKILLVQQDREELWTKNEELNsenkkilkqKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1137
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELL---------KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1138 SSESTLLQQLKELQANKDAVDVACQKHIKERE---ELEHYQKLLEENDRVIKDKDDVIQR--------LQSSYDDLA-RN 1205
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRLQAVVvEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1206 QRELLQEVSILTAERDS-------AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQA 1278
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKdEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLAEREELvnen 1358
Cdd:TIGR02168  635 LELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE--LEEKIEELEEKIAELEKALAELRKEL---- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1359 kavtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1438
Cdd:TIGR02168  708 ----EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1439 QEldfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1518
Cdd:TIGR02168  784 IE--------------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1519 CSSDIEILNRERTELQDKCQKLTGEVENMKEnltvekkarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE 1598
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1599 LLVQEKEKSETKLEEvikekmilyketeqLASKIEQLKSDFTSLsvskaeledvhscVSVMLDELQHKYEVTEKEKMELV 1678
Cdd:TIGR02168  919 ELREKLAQLELRLEG--------------LEVRIDNLQERLSEE-------------YSLTLEEAEALENKIEDDEEEAR 971

                          890       900       910
                   ....*....|....*....|....*....|.
gi 2024359632 1679 QENESLHAEWKSLVIINEEILKEKEKLSKEY 1709
Cdd:TIGR02168  972 RRLKRLENKIKELGPVNLAAIEEYEELKERY 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 875-1769 1.22e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 90.13  E-value: 1.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  875 ELRLKERQLEQIQLELTKANEKAVQLQKNVEqtaqKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 954
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRRERE----KAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  955 EKETSEmitkhdadikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAE-QAKSLSSVLASARKEIELMSDKMRDLIS 1033
Cdd:TIGR02169  254 EKLTEE------------------ISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1034 EKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1113
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1114 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQ 1193
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1194 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSRE-ELCVSLANT 1272
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1273 ANENQA--------LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASE 1344
Cdd:TIGR02169  553 VVEDDAvakeaielLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1345 QRLLAERE------ELVNENKAVTEKLTKATADAVLAeTAFTEKINELNLEKESVfskslqfEKHNEALLREKDELERKY 1418
Cdd:TIGR02169  633 RRLMGKYRmvtlegELFEKSGAMTGGSRAPRGGILFS-RSEPAELQRLRERLEGL-------KRELSSLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1419 SELLDEKKSLENAFSDMKREQELdfsakrlLVQENTTLKYSIEALEEELKKKNlenQELIACRSDLSDLLKEAQDARRTL 1498
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1499 ENELAAVSHAKQVLSSSFntcssdIEILNRERTELQDKCQKLTGEVENMKenltvekkaRILDKESFLLErmelqnnigF 1578
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSR------IPEIQAELSKLEEEVSRIEARLREIE---------QKLNRLTLEKE---------Y 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1579 LEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSV 1658
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1659 MLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEIL------KEKEKLSKEYYKLhEKVVALLEQTDADFSCRLL 1732
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqAELQRVEEEIRAL-EPVNMLAIQEYEEVLKRLD 989

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 2024359632 1733 VSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEA 1769
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 354-1045 1.81e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.81e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDrhvlEMEAKMDQLRAMVEAADREKVELLNQLE 433
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  434 EEKRKVEDLQFRVEEESITKGDLERKRQI-SEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSR 512
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  513 IMELERDLALRVKEVAELRGRLESSKhiddvdtslSLLQEISSLQEKMAAAgKEHQREMS----------SLKEKFESS- 581
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSLE---------RLQENLEGFSEGVKAL-LKNQSGLSgilgvlseliSVDEGYEAAi 539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  582 EEALRKEIKTLSASNERMG-------KENES-------LKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFN 647
Cdd:TIGR02168  540 EAALGGRLQAVVVENLNAAkkaiaflKQNELgrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  648 kGVGAQTAEFAELKTQMEKVKLDYENEM----------------------SNLKLKQENEKSQHLKEIEALKAKLlevtE 705
Cdd:TIGR02168  620 -YLLGGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsaktNSSILERRREIEELEEKIEELEEKI----A 694

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  706 EKEQTLENLKAKLESVEDqhlvEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLsavnqvkDSLEKELQLLKEKF 785
Cdd:TIGR02168  695 ELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI-------AQLSKELTELEAEI 763

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  786 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDS 865
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  866 SAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEqtaqkaeqSQQETLKTHQEELKKMQDQLTDMKKQMETSQN 945
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA--------SLEEALALLRSELEELSEELRELESKRSELRR 915

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  946 QYKDLQAKYEKEtSEMITKHDADIKGFKQNL-----LDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKE 1020
Cdd:TIGR02168  916 ELEELREKLAQL-ELRLEGLEVRIDNLQERLseeysLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEE 994

                          730       740
                   ....*....|....*....|....*
gi 2024359632 1021 IELMSDKMRDLISEKETLAQERNTL 1045
Cdd:TIGR02168  995 YEELKERYDFLTAQKEDLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 992-1846 2.59e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 2.59e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  992 ELETQAEELKKQAEQA---KSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKI 1063
Cdd:TIGR02168  197 ELERQLKSLERQAEKAeryKELKAELRELELALLVLRleelrEELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1064 LLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQestekvalisekskLLSEIETAQADLLKITQENDALRSSESTL 1143
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLAN--------------LERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1144 LQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLaRNQRELLQevsiltaerdsa 1223
Cdd:TIGR02168  343 EEKLEELKEELES----------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL-ELQIASLN------------ 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1224 qekdldlksthialkNEIDCLLQTNRSLQSEKEMLLKSREELcvslantanENQALKLRKDEMQTELETEREKLEKMTKD 1303
Cdd:TIGR02168  400 ---------------NEIERLEARLERLEDRRERLQQEIEEL---------LKKLEEAELKELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1304 NMDLKASLSSLSNFLEEMKSSREASNSEKIHLlqEALFASEQRLLAEREELVNENKAVT-EKLTKATADAVLAETAFTEk 1382
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQENLEGFSEGVKALLkNQSGLSGILGVLSELISVD- 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1383 iNELNLEKESVFSKSLQfekhneALLREKDELERKYSELLDEKKSLENAFS--DMKREQELDFSAKRLLVQENTTLKYSI 1460
Cdd:TIGR02168  533 -EGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1461 EALEEELKKKNLENQELIACRsdLSDLLKEAQDARRTLENELAAVSHAKQVLSSSF-------NTCSSD------IEILN 1527
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVL--VVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSIlerrreIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1528 RERTELQDKCQKLTGEVENMKENLT-VEKKARILDKESFLLERM--ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK 1604
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEeLEEELEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1605 EKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESL 1684
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1685 HAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvSEGKHELLLEEMSNLALKLREIErlqaqtfm 1764
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS--------LEEALALLRSELEELSEELRELE-------- 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1765 qkfeadKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQT-NEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1843
Cdd:TIGR02168  908 ------SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKI 981


                   ...
gi 2024359632 1844 EEL 1846
Cdd:TIGR02168  982 KEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 962-1855 2.84e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.50  E-value: 2.84e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  962 ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAkslssvlasarkeielmsDKMRDLISEKEtlaqe 1041
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA------------------ERYQALLKEKR----- 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1042 rntlKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEkskllsEIET 1121
Cdd:TIGR02169  222 ----EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLR 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1122 AQADLLKITQENDALRSSESTLLQQLKELQAnkdavdvacqKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD 1201
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEE----------RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1202 LARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKL 1281
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1282 RKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMkssreasnSEKIHLLQEALFASEQRLLAEREElVNENKAV 1361
Cdd:TIGR02169  442 EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV--------EKELSKLQRELAEAEAQARASEER-VRGGRAV 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1362 TE--------------KLTKATADAVLA-ETAFTEKINELNLEKESVFSKSLQFEKHNEA-----LLREKDELERKYSEL 1421
Cdd:TIGR02169  513 EEvlkasiqgvhgtvaQLGSVGERYATAiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1422 LDEKKSLENAFSDMKREQEldFSAKRLLVQENTTLKYSIEAleeelKKKNLENQELIACRSDL----------SDLLKEA 1491
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPK--YEPAFKYVFGDTLVVEDIEA-----ARRLMGKYRMVTLEGELfeksgamtggSRAPRGG 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1492 QDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTvekkaRILDKESFLLERME 1571
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE-----QLEQEEEKLKERLE 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1572 -LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVikEKMILYKETEQLASKIEQLKSDFTSLSVSKAELE 1650
Cdd:TIGR02169  741 eLEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1651 dvhscvsVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALleqtdadfscr 1730
Cdd:TIGR02169  819 -------QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL----------- 880

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1731 llvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIH------QEKIETLASLENS 1804
Cdd:TIGR02169  881 ----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedEEIPEEELSLEDV 956

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1805 RQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKL 1855
Cdd:TIGR02169  957 QAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 416-1225 5.53e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 5.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  416 AMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKELEQSLLFEKTKADKL 495
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  496 QRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLE--SSKHIDDVDTSL-SLLQEISSLQEKMAAAgKEHQREMS 572
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKdlGEEEQLRVKEKIgELEAEIASLERSIAEK-ERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  573 SLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLdhanKENSDVIELWKSKLESAIASHQQAMEELKvSFNKGVGA 652
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEY----AELKEELEDLRAELEEVDKEFAETRDELK-DYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  653 QTAEFAELKTQMEKV---KLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVtEEKEQTLENLKAKLESVEDQHlvem 729
Cdd:TIGR02169  397 LKREINELKRELDRLqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI-KKQEWKLEQLAADLSKYEQEL---- 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  730 EDTLNKLQEAEIKVSNLTKELQGKE---QKLLDLEKNLSAVNQVKDS-------LEKELQLLKEKFTSAVDGA------- 792
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEaqaRASEERVRGGRAVEEVLKAsiqgvhgTVAQLGSVGERYATAIEVAagnrlnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  793 ------------------ENAQRAMQETINKLNQKEEQ-----------FALMSSELEQLKSNLTVM---ETKLKEREE- 839
Cdd:TIGR02169  552 vvveddavakeaiellkrRKAGRATFLPLNKMRDERRDlsilsedgvigFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEa 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  840 -REQQLTEAKVKLENDIAE--------IMKSSGDSS------AQLMKMNDELRLKERQLEQIQLELTKAnekavqlqknv 904
Cdd:TIGR02169  632 aRRLMGKYRMVTLEGELFEksgamtggSRAPRGGILfsrsepAELQRLRERLEGLKRELSSLQSELRRI----------- 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  905 eqtaqkaeqsqqetlkthQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNLLDAEEALK 984
Cdd:TIGR02169  701 ------------------ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL-KERLEELEEDLSSLEQEIENVKSELK 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  985 AAQKKNDELETQAEELKKQAE--QAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESK 1062
Cdd:TIGR02169  762 ELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1063 ILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSEST 1142
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE 921

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1143 LLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRV---IKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAE 1219
Cdd:TIGR02169  922 LKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVeeeIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE 1001


                   ....*.
gi 2024359632 1220 RDSAQE 1225
Cdd:TIGR02169 1002 RKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 358-1008 9.47e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.47e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  358 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHdrhvLEMEAKMDQLRAMVEAADREKVELLNQLEEEKR 437
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  438 KVEDLQFRVEEESITKGDLERKRQISEDPENTQTKlehaRIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELE 517
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEE----KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  518 RDLALRVKEVAELRGRLES-SKHIDDVDTSLS-LLQEISSLQEKMAAAGK--------EHQREMSSLKEKFESSEEALRK 587
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERlEARLERLEDRRErLQQEIEELLKKLEEAELkelqaeleELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  588 ----------EIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSK-----------------------LESAIAS 634
Cdd:TIGR02168  466 lreeleeaeqALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQsglsgilgvlselisvdegyeaaIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  635 HQQAME-------ELKVSFNKGVGAQTAEFAELKTqmekVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKL------- 700
Cdd:TIGR02168  546 RLQAVVvenlnaaKKAIAFLKQNELGRVTFLPLDS----IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyl 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  701 ---LEVTEEKEQTLENLKAKLES----VEDQHLV--------EMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLs 765
Cdd:TIGR02168  622 lggVLVVDDLDNALELAKKLRPGyrivTLDGDLVrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKAL- 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  766 avnqvkDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT 845
Cdd:TIGR02168  701 ------AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  846 EAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEE 925
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ-IEELSED 853

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  926 LKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsemitKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE 1005
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERA--------SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA 925


                   ...
gi 2024359632 1006 QAK 1008
Cdd:TIGR02168  926 QLE 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1133-1926 1.60e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 1.60e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1133 NDALRSSESTLL-QQLKELQANKDAVDVACQKHIKEREELehyQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQ 1211
Cdd:TIGR02168  219 KAELRELELALLvLRLEELREELEELQEELKEAEEELEEL---TAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1212 EVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELE 1291
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1292 TEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL---VNENKAVTEKLTKA 1368
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1369 TADAVLAETAFTEKINELNLEKESVFSK--SLQFEKHN-EALLREKDELERKYSELLDEKKSLENAFS--------DMKR 1437
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERElaQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvDEGY 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1438 EQELDF----SAKRLLVQENTTLKYSIEALEEELKKK------------------NLENQELIACRSDLSDLLKEAQDAR 1495
Cdd:TIGR02168  536 EAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldsikgteiqgndREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1496 RTLENELAAVshakqVLSSSFNTCSSDIEILNRERT------ELQDKCQKLTGEVENmKENLTVEKKARILDKESfllER 1569
Cdd:TIGR02168  616 KALSYLLGGV-----LVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAK-TNSSILERRREIEELEE---KI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1570 MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAEL 1649
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1650 EDvhscvsvMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvVALLEQTDADFSC 1729
Cdd:TIGR02168  767 EE-------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER-LESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1730 RLLVSEGKHELLLEEMSNLALKLRE----IERLQAQT------FMQKFEADKRAEEVLQTMEKVTKEKDaihQEKIETLA 1799
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEEleelIEELESELeallneRASLEEALALLRSELEELSEELRELE---SKRSELRR 915

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1800 SLENSRQTNEKLQNELDMLKQNNLKNEEELTkSKELLNLENKKVEELKKEFEALKLAAAQKS--QQLAALQEENVKLAEE 1877
Cdd:TIGR02168  916 ELEELREKLAQLELRLEGLEVRIDNLQERLS-EEYSLTLEEAEALENKIEDDEEEARRRLKRleNKIKELGPVNLAAIEE 994

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632 1878 LgrsrdevtshQKLEEERSVLNNQLLEMKKSLpsNTLRESTlkKEIDEE 1926
Cdd:TIGR02168  995 Y----------EELKERYDFLTAQKEDLTEAK--ETLEEAI--EEIDRE 1029
PTZ00121 PTZ00121
MAEBL; Provisional
 345-1128 1.99e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.80  E-value: 1.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  345 ARKISGTTALQEALKE-----KQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvRDGHDRHVLEMEAKMDQLRamvE 419
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDaeeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAK---K 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  420 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKELEQSLlfEKTKADKLQREL 499
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAE--EKAEAAEKKKEE 1375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  500 EDTRVATV----SEKSRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGK--------EH 567
Cdd:PTZ00121  1376 AKKKADAAkkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKadeakkkaEE 1455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  568 QREMSSLKEKFESSEEALRKEIKTLSASN-ERMGKENESLKTKLDHANKENsdviELWKSKLESAIASHQQAMEELKvsf 646
Cdd:PTZ00121  1456 AKKAEEAKKKAEEAKKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAA----EAKKKADEAKKAEEAKKADEAK--- 1528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  647 nKGVGAQTAEfaELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHL 726
Cdd:PTZ00121  1529 -KAEEAKKAD--EAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  727 VEMEDTLNKLQEAEIKVSNLTKElqgkeqklldleknlsavnqvkDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK- 805
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKA----------------------EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKa 1663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  806 --LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIaeimkssgdssaqlmkmndelrlkeRQL 883
Cdd:PTZ00121  1664 aeEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEK-------------------------KKA 1718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  884 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMIT 963
Cdd:PTZ00121  1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD----EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  964 KHDADIKGFKQNLLDAEEALKAAQKK-NDELETQAEELKkqaEQAKSLSSVLASArKEIELMSDKMRDLISEKETLAQER 1042
Cdd:PTZ00121  1795 EVDKKIKDIFDNFANIIEGGKEGNLViNDSKEMEDSAIK---EVADSKNMQLEEA-DAFEKHKFNKNNENGEDGNKEADF 1870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1043 NTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSR--QESTEKVALISEKSKLLSEIE 1120
Cdd:PTZ00121  1871 NKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRdaEETREEIIKISKKDMCINDFS 1950


                   ....*...
gi 2024359632 1121 TAQADLLK 1128
Cdd:PTZ00121  1951 SKFCDYMK 1958
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 357-1100 3.84e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 78.57  E-value: 3.84e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  357 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQLEE 434
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  435 EKRKVEdlqfrvEEESITKGDLERKRQISEDPENTQTKLE------HARIKELEQSLLFEKTKADKLQRELEDTRVATVS 508
Cdd:TIGR02169  295 KIGELE------AEIASLERSIAEKERELEDAEERLAKLEaeidklLAEIEELEREIEEERKRRDKLTEEYAELKEELED 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  509 EKSRIMELERDLALRVKEVAELRGRLESSKH-IDDVDTSLSLLQEissLQEKMAAAGKEHQREMSSLKEK---FESSEEA 584
Cdd:TIGR02169  369 LRAELEEVDKEFAETRDELKDYREKLEKLKReINELKRELDRLQE---ELQRLSEELADLNAAIAGIEAKineLEEEKED 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  585 LRKEIK-------TLSASNERMGKENESLKTKLDHANKENSDVielwKSKLESAIASHQQ---------AMEELKVSFNK 648
Cdd:TIGR02169  446 KALEIKkqewkleQLAADLSKYEQELYDLKEEYDRVEKELSKL----QRELAEAEAQARAseervrggrAVEEVLKASIQ 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  649 GVGAQTAEFAELKTQMEK-VKLDYENEMSNLKLKQEN---EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ 724
Cdd:TIGR02169  522 GVHGTVAQLGSVGERYATaIEVAAGNRLNNVVVEDDAvakEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  725 --HLVEME------------DTL--NKLQEA-----EIKVSNLTKEL--------------QGKEQKLLDLEKNLSAVNQ 769
Cdd:TIGR02169  602 avDLVEFDpkyepafkyvfgDTLvvEDIEAArrlmgKYRMVTLEGELfeksgamtggsrapRGGILFSRSEPAELQRLRE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  770 VKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKereEREQQLTEAKV 849
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---SLEQEIENVKS 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  850 KLENDIAEIMKSSGDSSAQLMKMND-ELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK------AEQSQQETLKTH 922
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKlnrltlEKEYLEKEIQEL 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  923 QEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1002
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLNGKKEELEEE-LEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRK 917

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1003 QAEQAKSLSSVLASARKEIELMSDKMRDLISEK---ETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1079
Cdd:TIGR02169  918 RLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAK 997

                          810       820
                   ....*....|....*....|.
gi 2024359632 1080 LNSENKKILKQKEAAEAKSRQ 1100
Cdd:TIGR02169  998 LEEERKAILERIEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 690-1303 5.89e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 5.89e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  690 LKEIEALKAKLLEV---TEEKEQTLENLKA---------KLESVEDQHLVEMedTLNKLQEAEIKVSNLTKELQGKEQKL 757
Cdd:COG1196    178 ERKLEATEENLERLediLGELERQLEPLERqaekaeryrELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAEL 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  758 LDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKER 837
Cdd:COG1196    256 EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  838 EEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQE 917
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEAEEALLE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  918 TLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadikgfkqnLLDAEEALKAAQKKNDELETQA 997
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE---------------EEALLELLAELLEEAALLEAAL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  998 EELKKQAEQAKSLSSVLASARKEIELMSD--KMRDLISEKETLAQERNTLkLEKESLLSQHLEMESKILLVQQDREelwt 1075
Cdd:COG1196    480 AELLEELAEAAARLLLLLEAEADYEGFLEgvKAALLLAGLRGLAGAVAVL-IGVEAAYEAALEAALAAALQNIVVE---- 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1076 kNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKD 1155
Cdd:COG1196    555 -DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1156 AVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLqssyddLARNQRELLQEVSILTAERDSAQEKDLDLKSTHI 1235
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA------LLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632 1236 ALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKD 1303
Cdd:COG1196    708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 976-1503 9.88e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 9.88e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  976 LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSS--------------VLASARKEIELMSDKMRDLISEKETLAQE 1041
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAelaeleaeleelrlELEELELELEEAQAEEYELLAELARLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1042 RNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIET 1121
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1122 AQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD 1201
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLE---EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1202 LARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKL 1281
Cdd:COG1196    461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1282 RKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE----ALFASEQRLLAEREELVNE 1357
Cdd:COG1196    541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIgaavDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1358 NKAV----TEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFS 1433
Cdd:COG1196    621 TLLGrtlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1434 DMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELA 1503
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1284-2051 4.42e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.10  E-value: 4.42e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1284 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLA-EREELVNENKAVT 1362
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--KAERYQALLKEKREYEGYELLkEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1363 EKLtkATADAVLAEtaFTEKINELNLEKESVFSKSLQFEKHNEALLR-EKDELERKYSELLDEKKSLENAFSDMKREQEL 1441
Cdd:TIGR02169  244 RQL--ASLEEELEK--LTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1442 DFSAKRLLVQENTTLKYSIEALEEELKKKNLEnqeliacRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1521
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKR-------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1522 DIEILNRERTE-------LQDKCQKLTGEVENMKENLTVeKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFL 1594
Cdd:TIGR02169  393 KLEKLKREINElkreldrLQEELQRLSEELADLNAAIAG-IEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1595 TEKELLVQEKEKSETKLEEVIKEkmILYKETEQLASKIEQLKSDFTSLsVSKAELEDVHSCVSvMLDELQHKY------- 1667
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRE--LAEAEAQARASEERVRGGRAVEE-VLKASIQGVHGTVA-QLGSVGERYataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1668 ------------EVTEKEKMELVQENESLHAEWKSLVIINEEiLKEKEKLSK-----------EYYKLHEKVVA------ 1718
Cdd:TIGR02169  545 agnrlnnvvvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEdgvigfavdlvEFDPKYEPAFKyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1719 -LLEQTDAD----FSCRLLVSEGKhelLLEE---MSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAI 1790
Cdd:TIGR02169  624 lVVEDIEAArrlmGKYRMVTLEGE---LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1791 HQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEE 1870
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1871 NVKLAEELGRSR-DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEI----------DEERASLQKSISDTS 1938
Cdd:TIGR02169  781 LNDLEARLSHSRiPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIqelqeqridlKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1939 ALITQKDEELEKLRNEITVLRGEnasAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDE 2018
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESR---LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2024359632 2019 SAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2051
Cdd:TIGR02169  938 DPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 692-1597 4.93e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.10  E-value: 4.93e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  692 EIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ---------HLVEMEDTLNKLQEAEIKVsnLTKELQGKEQKLLDLEK 762
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQlerlrrereKAERYQALLKEKREYEGYE--LLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  763 NLSAVNQVKDSLEKELQLLKEKFTSAVDG-AENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREERE 841
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLlEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  842 QQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlkERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsQQETLKT 921
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEEL---------------------EREIEEERKRRDKLTEEYAELKEELEDLRAELEE-VDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  922 HQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIKGFKQNLLDAEEalkaaqkkndELETQAEELK 1001
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-LADLNAAIAGIEAKINELEE----------EKEDKALEIK 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1002 KQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELN 1081
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1082 SENKKILKQKEAAEAKSRQE---STEKVAliSEKSKLLSEIETAQADLLKITQENDALRssestLLQQLKELQANKDAVD 1158
Cdd:TIGR02169  532 SVGERYATAIEVAAGNRLNNvvvEDDAVA--KEAIELLKRRKAGRATFLPLNKMRDERR-----DLSILSEDGVIGFAVD 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1159 -VACQKHIKER-----------EELEHYQKLLEENDRV-----IKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERD 1221
Cdd:TIGR02169  605 lVEFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKYRMVtlegeLFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1222 SaqekdldlksthiaLKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMT 1301
Cdd:TIGR02169  685 G--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1302 KDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAER-----------EELVNENKAVTEKLTKATA 1370
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELE--------EDLHKLEEALNDLEARLSHSRipeiqaelsklEEEVSRIEARLREIEQKLN 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1371 DAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREqeldfsakrllv 1450
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE------------ 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1451 qenttlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSfNTCSSDIEILNRER 1530
Cdd:TIGR02169  891 ---------RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEI-PEEELSLEDVQAEL 960

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632 1531 TELQDKCQKLtGEVeNMKEnltvekkarILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEK 1597
Cdd:TIGR02169  961 QRVEEEIRAL-EPV-NMLA---------IQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 353-1002 9.63e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 9.63e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  353 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 432
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  433 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpentqtkLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSR 512
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  513 IMELERDLALRVKEVAELRGRLEsskhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKfESSEEALRKEIKTL 592
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALL------------EAEAELAEAEEELEELAEELLEALRAAAEL-AAQLEELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  593 SASNERMGKENESLKTKLDHANKEnSDVIELWKSKLESAIASHQQAMEELKVSfnkgVGAQTAEFAELKTQMEKVKLDYE 672
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEE-EEEEEEALEEAAEEEAELEEEEEALLEL----LAELLEEAALLEAALAELLEELA 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  673 NEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLenlkakleSVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQG 752
Cdd:COG1196    488 EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV--------AVLIGVEAAYEAALEAALAAALQNIVVEDDEVA 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  753 KEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMqetinklnqkEEQFALMSSELEQLKSNLTVMET 832
Cdd:COG1196    560 AAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVAS----------DLREADARYYVLGDTLLGRTLVA 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  833 KLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE 912
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  913 QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDA---DIKGFKQNL-------LDAEEA 982
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEElerELERLEREIealgpvnLLAIEE 789

                          650       660
                   ....*....|....*....|
gi 2024359632  983 LKAAQKKNDELETQAEELKK 1002
Cdd:COG1196    790 YEELEERYDFLSEQREDLEE 809
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 576-1405 9.68e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 9.68e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  576 EKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLE------SAIASHQQAMEELKVSFNKG 649
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEkreyegYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  650 VGAQTAEFAELKTQMEKVKLDYENemSNLKLKQENEKSQHLKEIE--ALKAKLLEVTEEKEQT-------------LENL 714
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEE--IEQLLEELNKKIKDLGEEEqlRVKEKIGELEAEIASLersiaekereledAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  715 KAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVnqvkdslEKELQLLKEKFTSAVDGAEN 794
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEV-------DKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  795 AQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND 874
Cdd:TIGR02169  397 LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  875 ELRLKERQLEQIQLELTKAnekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ---------- 944
Cdd:TIGR02169  477 EYDRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIevaagnrlnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  945 -------------NQYKDLQA---------KYEKETSEMITKHDADIKGFKQNLLDAE-----------------EALKA 985
Cdd:TIGR02169  552 vvveddavakeaiELLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDpkyepafkyvfgdtlvvEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  986 AQKKNDE--LETQAEELKKQ-------AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQH 1056
Cdd:TIGR02169  632 ARRLMGKyrMVTLEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1057 LEMESKILLVQQDREELwtkNEELNSENKKIlkqkEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDAL 1136
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQL---EQEEEKLKERL----EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1137 RSSESTllQQLKELQANKDAVDvacqkhikereelehyqklleendrvikdkdDVIQRLQSSYDDLARNQRELLQEVSIL 1216
Cdd:TIGR02169  785 EARLSH--SRIPEIQAELSKLE-------------------------------EEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1217 TAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREK 1296
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1297 LEKMTKDNMDLKASLSSLSNFLEEM-KSSREASNSEKIHLLQEALFASEQRLLAEREEL--VNeNKAVTE-KLTKATAD- 1371
Cdd:TIGR02169  912 IEKKRKRLSELKAKLEALEEELSEIeDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepVN-MLAIQEyEEVLKRLDe 990

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 2024359632 1372 -----AVLAE--TAFTEKINELNLEKESVFSKSlqFEKHNE 1405
Cdd:TIGR02169  991 lkekrAKLEEerKAILERIEEYEKKKREVFMEA--FEAINE 1029
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1068-1990 2.73e-12

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 72.77  E-value: 2.73e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1068 QDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1147
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1148 KELQANKDAVDVACQKHIKEREEleHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSI--LTAERDSAQE 1225
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYH--NHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqLQADRHQEHI 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1226 KDLDLKSTHIALKNEIDCLLQ---TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1302
Cdd:TIGR00606  364 RARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1303 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEK 1382
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQE 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1383 INELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDE------KKSLENAFSDMKREQ---ELDFSAKRLLVQEN 1453
Cdd:TIGR00606  524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEInqtRDRLAKLNKELASL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1454 TTLKYSIEALEEELKKKNLENQELI-------ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEIL 1526
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSSYEDKLfdvcgsqDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVC 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1527 NR------ERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELL 1600
Cdd:TIGR00606  684 QRvfqteaELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1601 VQEKEKSETKLEEVIKEkmilyketEQLAskiEQLKSDFTSLSVSKAELEDVhscvsvmldelqhkyevtEKEKMELVQE 1680
Cdd:TIGR00606  764 KNDIEEQETLLGTIMPE--------EESA---KVCLTDVTIMERFQMELKDV------------------ERKIAQQAAK 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1681 NESLhaewkSLVIINEEILKEKEKLSKEYYKLHEKVvALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQA 1760
Cdd:TIGR00606  815 LQGS-----DLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1761 QTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNnLKNEEELTKSKELLNLEN 1840
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK-VKNIHGYMKDIENKIQDG 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1841 KKVEELKKEFEALKLAAaqksqQLAALQEENVKLAEELGRSRDEVTSHQKLEeerSVLNNQLLEMKkslpsntlRESTLK 1920
Cdd:TIGR00606  968 KDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQE---RWLQDNLTLRK--------RENELK 1031

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1921 kEIDEERASLQKSISDTSalITQKDEELEKLRNEITVLRGENASAKTLQsvvKTLESDKLKLEEKVKNLE 1990
Cdd:TIGR00606 1032 -EVEEELKQHLKEMGQMQ--VLQMKQEHQKLEENIDLIKRNHVLALGRQ---KGYEKEIKHFKKELREPQ 1095
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 358-930 4.55e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 71.69  E-value: 4.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  358 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 426
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  427 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENTQTKLE------HARIKELeqSLLFEKTK--------- 491
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNLDDQLQklladlHKREKEL--SLEKEQNKrlwdrdtgn 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  492 ---ADKLQRELEDtrvatvseksRIMELERDLALRVKEVAELRGRLEsskhiddvdtslsllQEISSLQEKmaaagKEHQ 568
Cdd:pfam15921  411 sitIDHLRRELDD----------RNMEVQRLEALLKAMKSECQGQME---------------RQMAAIQGK-----NESL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  569 REMSSLKEKFESSEEALRKEIKTLSAsnERMGKEN-ESLKTKLDHANKENSDVIELWKS---KLESAIASHQQAMEELKV 644
Cdd:pfam15921  461 EKVSSLTAQLESTKEMLRKVVEELTA--KKMTLESsERTVSDLTASLQEKERAIEATNAeitKLRSRVDLKLQELQHLKN 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  645 SFNKGVGAQTaEFAELKTQM---EKVKLDYENEMSNL-KLKQENEKSQHLKEIEalKAKLLEVTEEKEQTLENLKAkLES 720
Cdd:pfam15921  539 EGDHLRNVQT-ECEALKLQMaekDKVIEILRQQIENMtQLVGQHGRTAGAMQVE--KAQLEKEINDRRLELQEFKI-LKD 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  721 VEDQHLVEMEDTLNKLQEAEIKVSNLTKEL--------QGKEQKLLDLEKNLSAVNqvkdSLEKELQLLKEKFTSAVDGA 792
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKLVNAGSERlravkdikQERDQLLNEVKTSRNELN----SLSEDYEVLKRNFRNKSEEM 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  793 E-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEA 847
Cdd:pfam15921  691 EtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  848 KVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELK 927
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846


                   ...
gi 2024359632  928 KMQ 930
Cdd:pfam15921  847 ELQ 849
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 5.91e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 70.87  E-value: 5.91e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 991-1769 6.04e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 6.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  991 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1067
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1068 QDREELwtkNEELNSenkkilKQKEAAEAKSRQESTEKvalisEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1147
Cdd:COG1196    274 LELEEL---ELELEE------AQAEEYELLAELARLEQ-----DIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1148 KELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1227
Cdd:COG1196    340 EELEEELEE----------AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1228 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELcvslANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1307
Cdd:COG1196    410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1308 KASLSSLSNFLEEMKSSREAsnsekihllqealFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1387
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEG-------------FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1388 LEKESVFSKSLQFEKHNEALLREKDELERkyselLDEKKSLENAFSDMKREQELDFsakrllvqenttlkysIEALEEEL 1467
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDK-----IRARAALAAALARGAIGAAVDL----------------VASDLREA 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1468 KKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVShakqvlsssfntcssdieilnRERTELQDKCQKLTGEVENM 1547
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT---------------------LEGEGGSAGGSLTGGSRREL 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1548 KENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQ 1627
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1628 LASKIEQLKSDFTSLsvsKAELEdvhscvsvmldelqhkyevtekekmELVQENESLHAewkslviINEEILKEKEKLSK 1707
Cdd:COG1196    751 EALEELPEPPDLEEL---ERELE-------------------------RLEREIEALGP-------VNLLAIEEYEELEE 795

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 1708 EYyklhekvVALLEQtdadfscrllvsegkHELLLEEMSNLALKLREIERLQAQTFMQKFEA 1769
Cdd:COG1196    796 RY-------DFLSEQ---------------REDLEEARETLEEAIEEIDRETRERFLETFDA 835
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 653-1550 6.19e-12

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 71.62  E-value: 6.19e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  653 QTAEFAELKTQMEKVKLDY-----ENEMSNLKLKQENEKSQHLKEI----EALKAKLLEVTEEKEQTLENLKAKLESVED 723
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQgqkvqEHQMELKYLKQYKEKACEIRDQitskEAQLESSREIVKSYENELDPLKNRLKEIEH 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  724 Q--HLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKlldleknlsavnqVKDSLEKELQLLKEKFTSAVDGAENAQRAMQE 801
Cdd:TIGR00606  260 NlsKIMKLDNEIKALKSRKKQMEKDNSELELKMEK-------------VFQGTDEQLNDLYHNHQRTVREKERELVDCQR 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  802 TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKER-EEREQQLTEAKVKLEND------------------IAEIMKSS 862
Cdd:TIGR00606  327 ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHiRARDSLIQSLATRLELDgfergpfserqiknfhtlVIERQEDE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  863 GDSSAQLM-KMNDELRLKERQLEQIQLELTKAN----------EKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQD 931
Cdd:TIGR00606  407 AKTAAQLCaDLQSKERLKQEQADEIRDEKKGLGrtielkkeilEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  932 -------QLTDMKKQMETS-QNQYKDLQAKYEKETSEMITKhDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQ 1003
Cdd:TIGR00606  487 lskaeknSLTETLKKEVKSlQNEKADLDRKLRKLDQEMEQL-NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSL 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1004 A---EQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILlvqqdrEELWTKNEEL 1080
Cdd:TIGR00606  566 LgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLF------DVCGSQDEES 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1081 NSENKKilkqkeaaeaKSRQESTEKVALISEKSKLLSEIETaqadllKITQENDALRSSESTLLQQLKELQANKDAVDVA 1160
Cdd:TIGR00606  640 DLERLK----------EEIEKSSKQRAMLAGATAVYSQFIT------QLTDENQSCCPVCQRVFQTEAELQEFISDLQSK 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1161 CQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSThIALKNE 1240
Cdd:TIGR00606  704 LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGT-IMPEEE 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1241 IDCLLQTNRSLQSEKEMLLKSREELCVSLAnTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEE 1320
Cdd:TIGR00606  783 SAKVCLTDVTIMERFQMELKDVERKIAQQA-AKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQH 861

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1321 MKSSREASNSEKIHLLQEAlfaseQRLLAEREELVNENKAVTEkLTKATADAVLAETAFTEKINELNLEKESVFSKSlqf 1400
Cdd:TIGR00606  862 LKSKTNELKSEKLQIGTNL-----QRRQQFEEQLVELSTEVQS-LIREIKDAKEQDSPLETFLEKDQQEKEELISSK--- 932

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1401 EKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsakrlLVQENTTLKYSIEALEEELKKKNLENQELIAC 1480
Cdd:TIGR00606  933 ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDY---------LKQKETELNTVNAQLEECEKHQEKINEDMRLM 1003

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1481 RSDLSdllkEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKEN 1550
Cdd:TIGR00606 1004 RQDID----TQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRN 1069
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 705-1320 6.42e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.20  E-value: 6.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  705 EEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEK 784
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  785 FTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD 864
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDK 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  865 SSAQLMKMNDEL---RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQME 941
Cdd:TIGR04523  192 IKNKLLKLELLLsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTE-ISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  942 TSQNQYKdlqakyekETSEMITKHDADIKGFKQNLLDAEEalkaaQKKNDELETQAEELKKQAEQAKSLSSVLASARKEI 1021
Cdd:TIGR04523  271 EKQKELE--------QNNKKIKELEKQLNQLKSEISDLNN-----QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1022 ELMSDKMRDLISEKETLAQERNTLKLEKEsllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQE 1101
Cdd:TIGR04523  338 SQLNEQISQLKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1102 STEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDA----VDVACQKHIKEREELEHYQKL 1177
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESletqLKVLSRSINKIKQNLEQKQKE 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1178 LEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS---------THIALKNEIDCLLQTN 1248
Cdd:TIGR04523  491 LKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKNKEI 570

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632 1249 RSLQSEKEMLLKSREELCVSLANTANENQALK---LRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEE 1320
Cdd:TIGR04523  571 EELKQTQKSLKKKQEEKQELIDQKEKEKKDLIkeiEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
476-1048 1.17e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.48  E-value: 1.17e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  476 ARIKELEqSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHIddvdtsLSLLQEISS 555
Cdd:PRK03918   176 RRIERLE-KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE------IEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  556 LQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSaSNERMGKENESLKTKLDHANKENSDvIELWKSKLESAIASH 635
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELRE-IEKRLSRLEEEINGI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  636 QQAMEELKvSFNKGVGAQTAEFAELKTQMEKVKLD---YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQT-- 710
Cdd:PRK03918   327 EERIKELE-EKEERLEELKKKLKELEKRLEELEERhelYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIee 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  711 -LENLKAKLESVEdQHLVEMEDTLNKLQEAEIK----------------VSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 773
Cdd:PRK03918   406 eISKITARIGELK-KEIKELKKAIEELKKAKGKcpvcgrelteehrkelLEEYTAELKRIEKELKEIEEKERKLRKELRE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  774 LEKELQLLKE--KFTSAVDGAENAQRAMQE-TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVK 850
Cdd:PRK03918   485 LEKVLKKESEliKLKELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKK 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  851 LENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKAnekavqlqknveQTAQKAEQSQQETLKTHQEELKKMQ 930
Cdd:PRK03918   565 LDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL------------KDAEKELEREEKELKKLEEELDKAF 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  931 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMItkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSL 1010
Cdd:PRK03918   633 EELAETEKRLEELRKELEELEKKYSEEEYEEL----------REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEE 702

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 2024359632 1011 SSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLE 1048
Cdd:PRK03918   703 LEEREKAKKELEKLEKALERVEELREKVKKYKALLKER 740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 565-1131 1.54e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 69.66  E-value: 1.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  565 KEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI-ELWKSKLESAIASHQQAMEELK 643
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQkNIDKIKNKLLKLELLLSNLKKK 209

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  644 VSFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhLKEIEALKAKLLEVTEEKEQTLENLKAKLESVED 723
Cdd:TIGR04523  210 IQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ-LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEK 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  724 QhLVEMEDTLNKL--QEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQE 801
Cdd:TIGR04523  289 Q-LNQLKSEISDLnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEE 367

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  802 TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKER 881
Cdd:TIGR04523  368 KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTN 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  882 QLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQeTLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEM 961
Cdd:TIGR04523  448 QDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQ-NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK-ISSLKEK 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  962 ITKHDADIKGFKQNLLDAEEALKA--AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmrDLISEKETla 1039
Cdd:TIGR04523  526 IEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ-------ELIDQKEK-- 596

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1040 qerntlklEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEI 1119
Cdd:TIGR04523  597 --------EKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKI 668

                          570
                   ....*....|..
gi 2024359632 1120 ETAQADLLKITQ 1131
Cdd:TIGR04523  669 KESKTKIDDIIE 680
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 346-1052 1.70e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.10  E-value: 1.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  346 RKISGTTALQEALKEKQQHIEQLLAE-----RDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEME------------ 408
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEElnkkiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEdaeerlakleae 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  409 -----AKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESiTKGDLERKRQISEDPENTQTKLEHARIKELEQ 483
Cdd:TIGR02169  331 idkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-KEFAETRDELKDYREKLEKLKREINELKRELD 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  484 SLLFEKTKADKlqrELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLES-SKHIDDVDTSLSLLQ--------EIS 554
Cdd:TIGR02169  410 RLQEELQRLSE---ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQlAADLSKYEQELYDLKeeydrvekELS 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  555 SLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHA--NKENSDV----------IE 622
Cdd:TIGR02169  487 KLQRELAEAEAQ-ARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAagNRLNNVVveddavakeaIE 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  623 LWKSKLES-----AIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKV---KLDYENEMSNLKLKQENEKSQHLKEIE 694
Cdd:TIGR02169  566 LLKRRKAGratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfkyVFGDTLVVEDIEAARRLMGKYRMVTLE 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  695 ---------------ALKAKLLEVTEEKEQtLENLKAKLESVEDqhlvEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLD 759
Cdd:TIGR02169  646 gelfeksgamtggsrAPRGGILFSRSEPAE-LQRLRERLEGLKR----ELSSLQSELRRIENRLDELSQELSDASRKIGE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  760 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSnltvmetklKEREE 839
Cdd:TIGR02169  721 IEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA---------RLSHS 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  840 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQLELTKANEKAVQ-----LQKNVEQTAQKAE 912
Cdd:TIGR02169  792 RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYleKEIQELQEQRIDLKEQIKSIEkeienLNGKKEELEEELE 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  913 QSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemiTKHDADIKGFKQNLLDAEEALKAAQKKNDE 992
Cdd:TIGR02169  872 ELEAA-LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK-----RKRLSELKAKLEALEEELSEIEDPKGEDEE 945

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632  993 -------LETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL 1052
Cdd:TIGR02169  946 ipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 408-1170 3.37e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.99  E-value: 3.37e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  408 EAKMDQLRAMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgDLERKRQ--ISEDPENTQTKLEHARIKEleQSL 485
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----ELHEKQKfyLRQSVIDLQTKLQEMQMER--DAM 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  486 LFEKTKADKLQRELEDTRVATVSEKSRIMELERD-LALRVKEVAELRGRLESSKHIddvdtslslLQEISS-LQEKMAAA 563
Cdd:pfam15921  130 ADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDmLEDSNTQIEQLRKMMLSHEGV---------LQEIRSiLVDFEEAS 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  564 GKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwksklesAIASHQQAMEELK 643
Cdd:pfam15921  201 GKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIEL-------LLQQHQDRIEQLI 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  644 VSFNKGVGAQTAEFAELKTQMEKVkldyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVED 723
Cdd:pfam15921  274 SEHEVEITGLTEKASSARSQANSI----QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  724 QHLV---EMEDTLNKLQEAEIKVSNLTKELQG------KEQKLLDLEKN----------------------LSAVNQVKD 772
Cdd:pfam15921  350 QLVLansELTEARTERDQFSQESGNLDDQLQKlladlhKREKELSLEKEqnkrlwdrdtgnsitidhlrreLDDRNMEVQ 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  773 SLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT----EAK 848
Cdd:pfam15921  430 RLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTaslqEKE 509

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  849 VKLENDIAEIMKSSGDSSAQLMKMN------DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsQQETLKTH 922
Cdd:pfam15921  510 RAIEATNAEITKLRSRVDLKLQELQhlknegDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-HGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  923 QEELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEMITKHdADIKGFKQNLLDA-EEALKAA----QKKN---DELE 994
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRELEARV-SDLELEKVKLVNAgSERLRAVkdikQERDqllNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  995 TQAEELKKQAEQAKSLSSVLASARKEIELMSDKMR-DLISEKETLAQERNTLKlekesllSQHLEMESKILLVQQDREEL 1073
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQTRNTLK-------SMEGSDGHAMKVAMGMQKQI 736

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1074 WTKNEELNSENKKILKQKEAAEAKSRqestEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQAN 1153
Cdd:pfam15921  737 TAKRGQIDALQSKIQFLEEAMTNANK----EKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVA 812

                          810       820
                   ....*....|....*....|
gi 2024359632 1154 KDAVDVA---CQKHIKEREE 1170
Cdd:pfam15921  813 LDKASLQfaeCQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 685-1427 4.22e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 4.22e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  685 EKSQHLKEIEALKAKLLEVTEEKEQTLE-NLKAKLESVEDqHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKN 763
Cdd:TIGR02169  195 EKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEA-LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  764 LSAVN-QVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQ 842
Cdd:TIGR02169  274 LEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  843 QLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTH 922
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA-IAGI 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  923 QEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1002
Cdd:TIGR02169  433 EAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--------LYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1003 QAEQAKSLSSVLAS-----------------------------------------ARKEIELMSD------------KMR 1029
Cdd:TIGR02169  505 RVRGGRAVEEVLKAsiqgvhgtvaqlgsvgeryataievaagnrlnnvvveddavAKEAIELLKRrkagratflplnKMR 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1030 DLISEKETLAQER------NTLKLEKE-----------SLLSQHLEMESKILlvqqDREELWTKNEELNSENKKIL---K 1089
Cdd:TIGR02169  585 DERRDLSILSEDGvigfavDLVEFDPKyepafkyvfgdTLVVEDIEAARRLM----GKYRMVTLEGELFEKSGAMTggsR 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1090 QKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvacQKHIKERE 1169
Cdd:TIGR02169  661 APRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLE---QEEEKLKE 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1170 ELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN------------QRELLQEVSILTAERDSAQEKDLDLKSTHIAL 1237
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDlhkleealndleARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1238 KNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELE-------TEREKLEKMTKDNMDLKAS 1310
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEeleaalrDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1311 LSSLSNFLEEMKSSREASNsEKIHLLQEALFASEQRL-----LAEREELVNENKAVTEKLtKATADAVLAETAFTEKINE 1385
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKR-KRLSELKAKLEALEEELseiedPKGEDEEIPEEELSLEDV-QAELQRVEEEIRALEPVNM 975

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 2024359632 1386 LNLEK-ESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKS 1427
Cdd:TIGR02169  976 LAIQEyEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1699-1998 7.91e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1699 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1778
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1779 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1858
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1859 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1938
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1939 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 1998
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1279-1957 9.21e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 9.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1279 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1355
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1356 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1430
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1431 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1508
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1509 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1569
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1570 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1640
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1641 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1717
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1718 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1793
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1794 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1861
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1862 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1922
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359632 1923 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1957
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 755-971 1.05e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.94  E-value: 1.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  755 QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKL 834
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  835 KEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN--------------DELRLKERQLEQIQLELTKANEKAVQL 900
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparreqaEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359632  901 QKNVEQ---TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKG 971
Cdd:COG4942    180 LAELEEeraALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 413-1150 1.42e-10

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 66.92  E-value: 1.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  413 QLRAMVEAADREKVELLNQLE--EEKRKVEDLQFRVEEESITKGDLERKR-QISEDPENTQTKLEHAR-------IKELE 482
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFplDQYTQLALMEFAKKKSLHGKAELLTLRsQLLTLCTPCMPDTYHERkqvlekeLKHLR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  483 QSLLFEKTKADKLQRELEDTRVATVSEK--SRIMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEI------- 553
Cdd:TIGR00618  233 EALQQTQQSHAYLTQKREAQEEQLKKQQllKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIeqqaqri 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  554 -SSLQEKMAAAGKEHQREMSSLKEkfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDV--IELWKSKLES 630
Cdd:TIGR00618  313 hTELQSKMRSRAKLLMKRAAHVKQ--QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhIHTLQQQKTT 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  631 AIASHQQAMEELKVSFNKG--VGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQE--NEKSQHLKEIEALKAKLLEVTEE 706
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQatIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAaiTCTAQCEKLEKIHLQESAQSLKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  707 KEQTLENLKAKLESVEDQHLVEmEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNlsavnqvkdslekelqllkekfT 786
Cdd:TIGR00618  471 REQQLQTKEQIHLQETRKKAVV-LARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL----------------------T 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  787 SAVDGAENAQRAMQETINKLNqkeeqfALMSSELEQLKSnltvmetkLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 866
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVY------HQLTSERKQRAS--------LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  867 AQLMKMND-ELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQN 945
Cdd:TIGR00618  594 VRLQDLTEkLSEAEDMLACEQHALLRKLQPEQDLQDVRLHL-QQCSQELALKLTALHALQLTLTQERVREHALSIRVLPK 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  946 QYKDL-QAKYEKETSEmitkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQaksLSSVLASARKEIELM 1024
Cdd:TIGR00618  673 ELLASrQLALQKMQSE------------KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE---IENASSSLGSDLAAR 737

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1025 SDKMRDLISEKE----------TLAQERNTLKLEKESLLSQHL-----EMESKILLVQQDREELWTKNEELNSENKKILK 1089
Cdd:TIGR00618  738 EDALNQSLKELMhqartvlkarTEAHFNNNEEVTAALQTGAELshlaaEIQFFNRLREEDTHLLKTLEAEIGQEIPSDED 817

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1090 QKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1150
Cdd:TIGR00618  818 ILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 782-1599 2.98e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 2.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  782 KEKFTSAVDGAENAQRAMQETINKLNQ-KEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQltEAKVKLEND 854
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQMErdamadIRRRESQSQE--DLRNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  855 IAEI----------MKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ-QETLKTHQ 923
Cdd:pfam15921  151 VHELeaakclkedmLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAiSKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  924 EELKKMQDQLTDMKKQMET----SQNQYKDLQAKYEKETSEMITKHDADIKGFKqnlldaeEALKAAQKKNDELETQAEE 999
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLT-------EKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1000 LKKQAEQAKSLSsvlasarkeielmsdkMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1079
Cdd:pfam15921  304 IQEQARNQNSMY----------------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1080 LNSENKKILKQKEAAEAKSRQESTEkVALISEKSKLLSEIETAQADLLkitqenDALRSSESTLLQQLKELQANKDAVDV 1159
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKE-LSLEKEQNKRLWDRDTGNSITI------DHLRRELDDRNMEVQRLEALLKAMKS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1160 ACQKHIKER--------EELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQREllqeVSILTAerdSAQEKDLDLK 1231
Cdd:pfam15921  441 ECQGQMERQmaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT----VSDLTA---SLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1232 STH---IALKNEIDCLLQTNRSLQSEKEmllksreelcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKdnmdlk 1308
Cdd:pfam15921  514 ATNaeiTKLRSRVDLKLQELQHLKNEGD-----------HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ------ 576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1309 aslsslsnFLEEMKSSREASNSEKIHLLQEalfASEQRLlaEREELvnenkavteKLTKATADAVLAEtaFTEKINELNL 1388
Cdd:pfam15921  577 --------LVGQHGRTAGAMQVEKAQLEKE---INDRRL--ELQEF---------KILKDKKDAKIRE--LEARVSDLEL 632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1389 EKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-----EQELDFSAKRL----------LVQEN 1453
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnkSEEMETTTNKLkmqlksaqseLEQTR 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1454 TTLKySIEALEEELKKKNLENQELIACRSDLSDLLkeaQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTEL 1533
Cdd:pfam15921  713 NTLK-SMEGSDGHAMKVAMGMQKQITAKRGQIDAL---QSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1534 QDKCQKLTGEVENMKENLTVEKKAriLDKESflLERMELQNNIGflEKEVEEMREKNKEFLTEKEL 1599
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVA--LDKAS--LQFAECQDIIQ--RQEQESVRLKLQHTLDVKEL 848
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1166-1994 3.42e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 3.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1166 KEREELEHYQKLLEENDRVIKDKDDVIQRLQSsyddlarnqrellqevsiltaERDSAqEKDLDLKSTHIalKNEIDCLL 1245
Cdd:TIGR02169  174 KALEELEEVEENIERLDLIIDEKRQQLERLRR---------------------EREKA-ERYQALLKEKR--EYEGYELL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1246 QTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM-DLKASLSSLSNFLEEMKSS 1324
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1325 REASNSEKIHLLQEA--LFASEQRLLAEREEL---VNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQ 1399
Cdd:TIGR02169  310 IAEKERELEDAEERLakLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1400 FEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK----KKNLENQ 1475
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEqlaaDLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1476 ELIACRSDLSDLLKEAQDARRtlenELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLtGEVE---------- 1545
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQR----ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL-GSVGeryataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1546 --NMKENLTVEK-----------KARILDKESFL-----------LERMELQNNIGFLEKEVEEMREKNKEFL------- 1594
Cdd:TIGR02169  545 agNRLNNVVVEDdavakeaiellKRRKAGRATFLplnkmrderrdLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtl 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1595 ------TEKELLVQ-----------EKEKSET----KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvh 1653
Cdd:TIGR02169  625 vvedieAARRLMGKyrmvtlegelfEKSGAMTggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-- 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1654 scvsvMLDELQHKYEVTEKEKMELVQENESLHAEwkslviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLlv 1733
Cdd:TIGR02169  703 -----RLDELSQELSDASRKIGEIEKEIEQLEQE--------EEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-- 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1734 segkhELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA-EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQ 1812
Cdd:TIGR02169  768 -----EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1813 NELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLE 1892
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENL----------NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI---EELE 909

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1893 EERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEEraslqKSISDTSALITQKDEELEKLRNEITVLRGENASA------- 1965
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGED-----EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeev 984

                          890       900       910
                   ....*....|....*....|....*....|...
gi 2024359632 1966 ----KTLQSVVKTLESDKLKLEEKVKNLEQKLK 1994
Cdd:TIGR02169  985 lkrlDELKEKRAKLEEERKAILERIEEYEKKKR 1017
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 542-1226 3.65e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 65.51  E-value: 3.65e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  542 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI 621
Cdd:pfam05483   69 DFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLI 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  622 E------LWKSKLESAIAS----------HQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENE 685
Cdd:pfam05483  148 KennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEM-----HFKLKEDHE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  686 KSQHLKEiealkaKLLEVTEEKEQTLENLKAKLESVEDQhlveMEDTLNKLQEAEIKVSNLtkelqgkEQKLLDLEKNLS 765
Cdd:pfam05483  223 KIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----MKDLTFLLEESRDKANQL-------EEKTKLQDENLK 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  766 AVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLK-------ERE 838
Cdd:pfam05483  286 ELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEattcsleELL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  839 EREQQLTEakvKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKaNEKAVQLQKNVEQTAQKAEQSQQE- 917
Cdd:pfam05483  366 RTEQQRLE---KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKIAEELKGKEQEl 441

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  918 --TLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMI------TKHDADIKGFKQNLLDAEEALKAAQKK 989
Cdd:pfam05483  442 ifLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIeltahcDKLLLENKELTQEASDMTLELKKHQED 521

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  990 NDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKEsllSQHLEMESKILL 1065
Cdd:pfam05483  522 IINCKKQEERMLKQIENLEekemNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKE---KQMKILENKCNN 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1066 VQQDREELWTKNEELNSENKKiLKQKEAAEAKSRQESTEKValisekSKLLSEIETAQADLLKIT----QENDALRSSES 1141
Cdd:pfam05483  599 LKKQIENKNKNIEELHQENKA-LKKKGSAENKQLNAYEIKV------NKLELELASAKQKFEEIIdnyqKEIEDKKISEE 671

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1142 TLLQQLKELQANKD-------AVDVACQKHIKEREELEHYQKllEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVS 1214
Cdd:pfam05483  672 KLLEEVEKAKAIADeavklqkEIDKRCQHKIAEMVALMEKHK--HQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELS 749

                          730
                   ....*....|..
gi 2024359632 1215 ILTAERDSAQEK 1226
Cdd:pfam05483  750 NIKAELLSLKKQ 761
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.27e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.27e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1743-1997 4.39e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 4.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1743 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1822
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1823 LKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK-----------L 1891
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeierlearlerL 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1892 EEERSVLNNQLLEMKKSLPSNTLRE-STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQS 1970
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          250       260
                   ....*....|....*....|....*..
gi 2024359632 1971 VVKTLESDKLKLEEKVKNLEQKLKAKS 1997
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLS 519
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1580-1994 5.05e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 5.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1580 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1659
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1660 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1739
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1740 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1819
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1820 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1894
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1895 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 1974
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359632 1975 LESDKLKLEEKVKNLEQKLK 1994
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 376-739 8.62e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 8.62e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  376 RAEVAKATSHVGEIEQELALVRDGHDrhvlEMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGD 455
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELE----ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  456 LERKRQisedpentqtkLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLE 535
Cdd:TIGR02168  759 LEAEIE-----------ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLE 827

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  536 SS-KHIDDVDTSLS-LLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHA 613
Cdd:TIGR02168  828 SLeRRIAATERRLEdLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  614 NKENSDVIELwKSKLESAIASHQQAMEELKVsfnkgvgaqtaEFAELKTQ-MEKVKLDYEN--EMSNLKLKQENEKSQHL 690
Cdd:TIGR02168  907 ESKRSELRRE-LEELREKLAQLELRLEGLEV-----------RIDNLQERlSEEYSLTLEEaeALENKIEDDEEEARRRL 974

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632  691 KEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEA 739
Cdd:TIGR02168  975 KRLENKIKELGPVNLAAIEEYEELKERYDFLTAQK-EDLTEAKETLEEA 1022
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1249-1835 1.29e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.29e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1249 RSLQSEKEMLLKSREELCVSLANTANenqaLKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREAS 1328
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1329 NSEKIHLLQ-EALFASEQRLLAEREELVNENKAVTEKLT---------KATADAVLAETAFTEKINELNLEKESVFSKSL 1398
Cdd:PRK03918   241 EELEKELESlEGSKRKLEEKIRELEERIEELKKEIEELEekvkelkelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1399 QFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENttlKYSIEALEEELKKKNLENQELI 1478
Cdd:PRK03918   321 EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE---RLKKRLTGLTPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1479 ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSsdieILNRERTELQDK--CQKLTGEVENMKENL-TVEK 1555
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCP----VCGRELTEEHRKelLEEYTAELKRIEKELkEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1556 KARILDKESFLLER-MELQNNIGFLEKEVEEMREKNKEFlteKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQ 1634
Cdd:PRK03918   474 KERKLRKELRELEKvLKKESELIKLKELAEQLKELEEKL---KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1635 LKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLhE 1714
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-D 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1715 KVVALLEQTDADF-SCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhQE 1793
Cdd:PRK03918   630 KAFEELAETEKRLeELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER-EK 708

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2024359632 1794 KIETLASLENSRQTNEKLQNELDMLKqnNLKNEEELTKSKEL 1835
Cdd:PRK03918   709 AKKELEKLEKALERVEELREKVKKYK--ALLKERALSKVGEI 748
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 582-1440 1.66e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 63.45  E-value: 1.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  582 EEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKgvgaqtaefaELK 661
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER----------IDL 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  662 TQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEI 741
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  742 KVSNLtkelqgkeqklldlEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELE 821
Cdd:pfam02463  322 EKKKA--------------EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLS 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  822 QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKavqlq 901
Cdd:pfam02463  388 SAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLK----- 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  902 knveqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEE 981
Cdd:pfam02463  463 -----DELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVA 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  982 ALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMES 1061
Cdd:pfam02463  538 VENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADE 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1062 KILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSES 1141
Cdd:pfam02463  618 DDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRR 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1142 TLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERD 1221
Cdd:pfam02463  698 QLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1222 SAQEKDLDLK--STHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEK 1299
Cdd:pfam02463  778 EEREKTEKLKveEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1300 MTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAF 1379
Cdd:pfam02463  858 RLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEP 937

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1380 TEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQE 1440
Cdd:pfam02463  938 EELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1325-2083 2.64e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.68  E-value: 2.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1325 REASNSEKIHLLQEALFASEQRLLAER-EELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKH 1403
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAkKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1404 NEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSD 1483
Cdd:pfam02463  260 IEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1484 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSfntcSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1563
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQEKLEQL----EEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1564 SFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSD----- 1638
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLsrqkl 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1639 --FTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKV 1716
Cdd:pfam02463  496 eeRSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1717 VALLEQT-DADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKI 1795
Cdd:pfam02463  576 GARKLRLlIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1796 ETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLA 1875
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKIN 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1876 EELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSlpsntlRESTLKKEIDEERASLQKSISDTS-ALITQKDEELEKLRNE 1954
Cdd:pfam02463  736 EELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSE------LSLKEKELAEEREKTEKLKVEEEKeEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1955 ITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQpltVTSPSGDIAANLLQDESAEDKQQEIDFLNSVI 2034
Cdd:pfam02463  810 LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEE---ELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632 2035 VDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEEEGLSKKTPRLFCD 2083
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 377-1367 2.70e-09

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 62.89  E-value: 2.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  377 AEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVE---AADREKVELLNQLEEEKRKVEDLQFRVEEESitk 453
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaEAEEMRARLAARKQELEEILHELESRLEEEE--- 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  454 gdlERKRQISEDPENTQTKleharIKELEQSLLFEKTKADKLQREledtrvaTVSEKSRIMELERDLALrvkeVAELRGR 533
Cdd:pfam01576   89 ---ERSQQLQNEKKKMQQH-----IQDLEEQLDEEEAARQKLQLE-------KVTTEAKIKKLEEDILL----LEDQNSK 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  534 LESSKhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESS----EEALRKEiktlsasnERMGKENESLKTK 609
Cdd:pfam01576  150 LSKER---------KLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMisdlEERLKKE--------EKGRQELEKAKRK 212

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  610 LDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFA------ELKTQMEKVKLDYENEMSnLKLKQE 683
Cdd:pfam01576  213 LEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkkirELEAQISELQEDLESERA-ARNKAE 291

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  684 NEKSQHLKEIEALKAKLL----------EVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNK-----------LQEAEIK 742
Cdd:pfam01576  292 KQRRDLGEELEALKTELEdtldttaaqqELRSKREQEVTELKKALEEETRSHEAQLQEMRQKhtqaleelteqLEQAKRN 371

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  743 VSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLE---KELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE 819
Cdd:pfam01576  372 KANLEKAKQALESENAELQAELRTLQQAKQDSEhkrKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNE 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  820 LE----QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANE 895
Cdd:pfam01576  452 AEgkniKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKK 531

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  896 KAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMetsQNQYKDLQAKYEKEtSEMITKHDADIKGFK 973
Cdd:pfam01576  532 KLEEDAGTLEAleEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRL---QQELDDLLVDLDHQ-RQLVSNLEKKQKKFD 607

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  974 QNLldAEEALKAAQKKNDELETQAEELKKQAeQAKSLSSVLASARKEIE-------LMSDKMRDLISEKETLAQERNTLK 1046
Cdd:pfam01576  608 QML--AEEKAISARYAEERDRAEAEAREKET-RALSLARALEEALEAKEelertnkQLRAEMEDLVSSKDDVGKNVHELE 684

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1047 LEKESLLSQHLEMESKI-----------------------LLVQQDReELWTKNEELNSENKKILKQKEAAEAKSRQEST 1103
Cdd:pfam01576  685 RSKRALEQQVEEMKTQLeeledelqatedaklrlevnmqaLKAQFER-DLQARDEQGEEKRRQLVKQVRELEAELEDERK 763

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1104 EKVALISEKSKLLSEIETAQADLlkitqenDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleENDR 1183
Cdd:pfam01576  764 QRAQAVAAKKKLELDLKELEAQI-------DAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSK---ESEK 833

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1184 VIKDKDDVIQRLQssyDDLARNQRELLQevsiLTAERDSAQEKDLDLKSTHIALKNEidcllqtNRSLQSEKEMLLKSRE 1263
Cdd:pfam01576  834 KLKNLEAELLQLQ---EDLAASERARRQ----AQQERDELADEIASGASGKSALQDE-------KRRLEARIAQLEEELE 899

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1264 ELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFAS 1343
Cdd:pfam01576  900 EEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQL 979

                         1050      1060
                   ....*....|....*....|....
gi 2024359632 1344 EQRLLAEREELVNENKAVTEKLTK 1367
Cdd:pfam01576  980 EEQLEQESRERQAANKLVRRTEKK 1003
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 902-1478 3.05e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.35  E-value: 3.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  902 KNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAK------YEKETSEMITKHDADIKGFKQN 975
Cdd:TIGR04523   25 KNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKikileqQIKDLNDKLKKNKDKINKLNSD 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  976 LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSL----SSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKES 1051
Cdd:TIGR04523  105 LSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNidkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLN 184

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1052 LLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEaaeaKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1131
Cdd:TIGR04523  185 IQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKK----QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKD 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1132 ENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL--EHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQREL 1209
Cdd:TIGR04523  261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1210 LQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTE 1289
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1290 LETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfaseqrlLAEREELVNENKAVTEKLTKAT 1369
Cdd:TIGR04523  421 KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ---------LKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1370 ADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRL- 1448
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIe 571

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2024359632 1449 -LVQENTTLKYSIEALEEELKKKNLENQELI 1478
Cdd:TIGR04523  572 eLKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 552-2064 3.98e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 62.38  E-value: 3.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  552 EISSLQEKMAAAGKEH-QREMSSLKEKFESSEEALRKEIKTLSASNERMGkENESLKTKLDHANKENSDVIELWKSKLES 630
Cdd:TIGR01612  285 DIDAAYKEHAAITHEHiDAELNDIKKHPMINDKELRPHGKRLIKILESEG-EQGHIINKLIFLEKEFEDTIHKSDIYKDE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  631 AIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKlkqeneksqHLKEIEALKAKLLEVTEEKEQT 710
Cdd:TIGR01612  364 CLSNHLFMEDYLKDD------KISPYYYEFLEEIKKIAKQRAIFFYNAK---------KLKHLEILYKHQEDILNNFHKT 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  711 LENLK-AKLESVEDQHLVEMEDTLN------KLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKdsleKELQLLKE 783
Cdd:TIGR01612  429 IERLIfEKPDPNNNNIFKDDFDEFNkpipksKLKALEKRFFEIFEEEWGSYDIKKDIDENSKQDNTVK----LILMRMKD 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  784 kFTSAVDGAENAQRAMQETINKLNQKEEQF--ALMSSELEQ-LKSNLTVM----ETKLKEREEREQQlTEAKVKLENDIA 856
Cdd:TIGR01612  505 -FKDIIDFMELYKPDEVPSKNIIGFDIDQNikAKLYKEIEAgLKESYELAknwkKLIHEIKKELEEE-NEDSIHLEKEIK 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  857 EIMKssgdssaQLMKMNDEL----RLKERQLEQIQlELTKANE---KAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKM 929
Cdd:TIGR01612  583 DLFD-------KYLEIDDEIiyinKLKLELKEKIK-NISDKNEyikKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNK 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  930 QDQLTDMKKqmETSQNQYKDLQAKYeKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELkkqaeqakS 1009
Cdd:TIGR01612  655 DKIYSTIKS--ELSKIYEDDIDALY-NELSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVEL--------H 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1010 LSSvlasarkeIELMSDKMRDLISE--KETLAQERNTLKLEKESLLSQHLEMESKIllvqqdrEELWTKNEELNSENKKI 1087
Cdd:TIGR01612  724 LSN--------IENKKNELLDIIVEikKHIHGEINKDLNKILEDFKNKEKELSNKI-------NDYAKEKDELNKYKSKI 788

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1088 LKQKEAAEAKSRQEST--EKVALISEKSK-LLSEIETAQADLLKITQEndalrssestlLQQLKELQANKDAVDVACQKH 1164
Cdd:TIGR01612  789 SEIKNHYNDQINIDNIkdEDAKQNYDKSKeYIKTISIKEDEIFKIINE-----------MKFMKDDFLNKVDKFINFENN 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1165 IKEREELEHYQKlleeNDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSiltaerdSAQEKDLDLKSTHIALKNEIDCL 1244
Cdd:TIGR01612  858 CKEKIDSEHEQF----AELTNKIKAEISDDKLNDYEKKFNDSKSLINEIN-------KSIEEEYQNINTLKKVDEYIKIC 926

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1245 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDnmdlkASLSSLsnfleemkss 1324
Cdd:TIGR01612  927 ENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKD-----ASLNDY---------- 991

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1325 rEASNSEKIHL---LQEALFASEQRLL----AEREELVNEnkaVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS 1397
Cdd:TIGR01612  992 -EAKNNELIKYfndLKANLGKNKENMLyhqfDEKEKATND---IEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKN 1067

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1398 LqfEKHNEALLREKDELERKYSELlDEKKSLENaFSDMKREQELDFS-----AKRLLVQENTTLKYSIEALEEELKKKNL 1472
Cdd:TIGR01612 1068 I--ELLNKEILEEAEINITNFNEI-KEKLKHYN-FDDFGKEENIKYAdeinkIKDDIKNLDQKIDHHIKALEEIKKKSEN 1143

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1473 ENQELIACRSDLSDLLKEA------QDARRTLENELAAVSHAKQVLSSsFNTCSSDIEILNRERTELQdkcqkltgEVEN 1546
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAisnddpEEIEKKIENIVTKIDKKKNIYDE-IKKLLNEIAEIEKDKTSLE--------EVKG 1214

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1547 MkeNLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-KNKEFLTEKELLVQEKEKSETKLEEVIKEKmilYKET 1625
Cdd:TIGR01612 1215 I--NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEiKEKSPEIENEMGIEMDIKAEMETFNISHDD---DKDH 1289

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1626 EQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIIN-EEILKEKEK 1704
Cdd:TIGR01612 1290 HIISKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKLNKiKKIIDEVKE 1369

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1705 LSKEYYKLHEKVVALLEQTDAdfscrlLVSEGKHELLLEEMSNlalklreierlqaqtfmqKFEADKRAEEVLQTMEKVT 1784
Cdd:TIGR01612 1370 YTKEIEENNKNIKDELDKSEK------LIKKIKDDINLEECKS------------------KIESTLDDKDIDECIKKIK 1425

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1785 KEKDAIHQEKIETLASLENSRQTNEKLQ---NELDM----------LKQNNLKNE-----EELTKSKELLNLENKKVEEL 1846
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLllfKNIEMadnksqhilkIKKDNATNDhdfniNELKEHIDKSKGCKDEADKN 1505

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1847 KKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSlpsntlrESTLKKEIDEe 1926
Cdd:TIGR01612 1506 AKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKS-------EQKIKEIKKE- 1577

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1927 raslQKSISDTSALITQKDEELEKLRNEItvlrgENASAKTLQ-SVVKTLESDKLKLEEKVKNLEQKLKAKSEQplTVTS 2005
Cdd:TIGR01612 1578 ----KFRIEDDAAKNDKSNKAAIDIQLSL-----ENFENKFLKiSDIKKKINDCLKETESIEKKISSFSIDSQD--TELK 1646

                         1530      1540      1550      1560      1570      1580      1590
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359632 2006 PSGDIAANLL--------QDESAEDKQQEIDFLNSVI------VDLQRRNEELNLkIQRMCEAAL-NGNEEETI 2064
Cdd:TIGR01612 1647 ENGDNLNSLQefleslkdQKKNIEDKKKELDELDSEIekieidVDQHKKNYEIGI-IEKIKEIAIaNKEEIESI 1719
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
760-955 4.16e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 61.96  E-value: 4.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  760 LEKNLSAVNQVKDSLEKELQLLKEKftsaVDGAENAQRAMQETiNKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 839
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKE----LEEAEAALEEFRQK-NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  840 REQQLTEAKVKLENDIAEIMkssgdSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVE-------------- 905
Cdd:COG3206    241 RLAALRAQLGSGPDALPELL-----QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAalraqlqqeaqril 315

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  906 -------QTAQKAEQSQQETLKTHQEELKKM---QDQLTDMKKQMETSQNQYKDLQAKYE 955
Cdd:COG3206    316 asleaelEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLE 375
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
406-937 5.10e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 5.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENTQTKLEhARIKELEQSL 485
Cdd:PRK03918   190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE-EKIRELEERI 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  486 LFEKTKADKLQ---RELEDTRvATVSEKSRIMELERDLALRVKEVAELRGRLESskHIDDVDTSLSLLQEISSLQEKMAA 562
Cdd:PRK03918   269 EELKKEIEELEekvKELKELK-EKAEEYIKLSEFYEEYLDELREIEKRLSRLEE--EINGIEERIKELEEKEERLEELKK 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  563 AGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDV------IELWKSKLESAIASHQ 636
Cdd:PRK03918   346 KLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIeeeiskITARIGELKKEIKELK 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  637 QAMEELKVSFNK-GVGAQTAEFAELKTQMEKVKLDYENEMSNLK--LKQENEKSQHLKEIEALKAKLLEVTEEKE--QTL 711
Cdd:PRK03918   426 KAIEELKKAKGKcPVCGRELTEEHRKELLEEYTAELKRIEKELKeiEEKERKLRKELRELEKVLKKESELIKLKElaEQL 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  712 ENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFtsavdg 791
Cdd:PRK03918   506 KELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKEL------ 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  792 aenaQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK 871
Cdd:PRK03918   580 ----EELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKK 655

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632  872 MNDE-LRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQETLKTHQEELKKMQDQLTDMK 937
Cdd:PRK03918   656 YSEEeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKALERVE 724
PTZ00121 PTZ00121
MAEBL; Provisional
 837-1471 5.89e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 5.89e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  837 REEREQQLTEAKVKLEND--IAEIMKSSGDSSAQLMKMNDELRLKE----RQLEQIQLELTKANEKAVQLQKNVEQTAQK 910
Cdd:PTZ00121  1194 RKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAeeakKAEEERNNEEIRKFEEARMAHFARRQAAIK 1273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  911 AEQSQQETLKTHQEELKKMQDqltdMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKN 990
Cdd:PTZ00121  1274 AEEARKADELKKAEEKKKADE----AKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK 1349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  991 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKEtlAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1070
Cdd:PTZ00121  1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAKKKA 1427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1071 EELwTKNEELnseNKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTllqQLKEL 1150
Cdd:PTZ00121  1428 EEK-KKADEA---KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA---KKKAD 1500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1151 QANKDAVDVACQKHIKEREELEHYQKLLEENDRviKDKDDVIQRLQSSYDDLARNQREL--LQEVSILTAERDSAQEKDL 1228
Cdd:PTZ00121  1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA--KKADEAKKAEEKKKADELKKAEELkkAEEKKKAEEAKKAEEDKNM 1578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1229 DLKSTHIALKNEidcllqtnrslqsekemllKSREELCVSLANTANENQALKLRKDemqtelETEREKLEKMTKDNMDLK 1308
Cdd:PTZ00121  1579 ALRKAEEAKKAE-------------------EARIEEVMKLYEEEKKMKAEEAKKA------EEAKIKAEELKKAEEEKK 1633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1309 ASLSSLSNFLEEMKSSREASNSEKIHLLQealfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNL 1388
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1389 EKESVFSKSLQFEKHNEALLREKDELERKYSElldEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK 1468
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786


                   ...
gi 2024359632 1469 KKN 1471
Cdd:PTZ00121  1787 EED 1789
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 873-1105 7.13e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 7.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  873 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQE------TLKTHQEELKKMQDQLTDMKKQMETSQNQ 946
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaalarRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  947 YKDLQAKYEKETSEMITKHDADIKGF---KQNLLDAEEALKAAQKKNDELETQAEELKKQAEQakslssvLASARKEIEL 1023
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-------LAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1024 MSDKMRDLISEKETLAQERNTLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQEST 1103
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ..
gi 2024359632 1104 EK 1105
Cdd:COG4942    249 AA 250
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1096-1893 7.33e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1096 AKSRQESTEKVALISEKSkllSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvACQKHIKEREELEHYQ 1175
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFD---RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1176 KL--LEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS-THIALKNEIDCLLQTNRSLQ 1252
Cdd:TIGR02169  228 LLkeKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1253 SEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEM----KSSREAS 1328
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1329 NSEKIHLlqEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALL 1408
Cdd:TIGR02169  388 KDYREKL--EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1409 REKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKK--------KNLENQELIAC 1480
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1481 RSDLS------------------DLLKEAQDARRTL--------ENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQ 1534
Cdd:TIGR02169  542 EVAAGnrlnnvvveddavakeaiELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFG 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1535 DkcqklTGEVENMKENLTVEKKARILDKESFLLER-----------MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQE 1603
Cdd:TIGR02169  622 D-----TLVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1604 KEK--------------SETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhscvsvMLDELQHKYEV 1669
Cdd:TIGR02169  697 LRRienrldelsqelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS-------ELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1670 TEKEKMELVQENESLHAEwkslviINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLvsegKHELLLEEMSNLA 1749
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEAR------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL----EKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1750 LKLREIErlqaqtfmqkfeaDKRAEevlqtmekVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEEL 1829
Cdd:TIGR02169  840 EQRIDLK-------------EQIKS--------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359632 1830 TKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEE 1893
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
911-1156 7.95e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 60.80  E-value: 7.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  911 AEQSQQETLKTHQEELKK----MQDQLTDMKKQMETSQNQYKDLQAKYeketsemitkhdadikgfkqNLLDAEEALKAA 986
Cdd:COG3206    158 AEAYLEQNLELRREEARKalefLEEQLPELRKELEEAEAALEEFRQKN--------------------GLVDLSEEAKLL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  987 QKKNDELETQAEELKKQAEQAKSLssvLASARKEIELMSDKMRDLISEKE--TLAQERNTLKLEKESLLSQHLEMESKIL 1064
Cdd:COG3206    218 LQQLSELESQLAEARAELAEAEAR---LAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1065 LVQQDREELwtkNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL 1144
Cdd:COG3206    295 ALRAQIAAL---RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371

                          250
                   ....*....|..
gi 2024359632 1145 QQLKELQANKDA 1156
Cdd:COG3206    372 QRLEEARLAEAL 383
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1523-2044 8.70e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.85  E-value: 8.70e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1523 IEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMrEKNKEFLTEKELLVQ 1602
Cdd:PRK03918   171 IKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1603 EKEKSETKLEEVIK--EKMI--LYKETEQLASKIEQLKS------DFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEK 1672
Cdd:PRK03918   249 SLEGSKRKLEEKIRelEERIeeLKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1673 EkmelVQENESLHAEWKSLVIINEEILKEKEKLsKEYYKLHEKVVALLEQTD---ADFSCR--------LLVSEGKHELL 1741
Cdd:PRK03918   329 R----IKELEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELErlkKRLTGLtpeklekeLEELEKAKEEI 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1742 LEEMSNLALKLREIERLQAQ--TFMQKFEADKRA----------EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1809
Cdd:PRK03918   404 EEEISKITARIGELKKEIKElkKAIEELKKAKGKcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1810 KLQNELdmlkqnnlKNEEELTKSKELL----NLENK-------KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEEL 1878
Cdd:PRK03918   484 ELEKVL--------KKESELIKLKELAeqlkELEEKlkkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1879 GRSRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESTLK---------KEIDEERASLQKSISDTSALITQKDEEL 1948
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1949 EKLRNEITVLRGENASAKTLQSV--VKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLlqdESAEDKQQE 2026
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL---EEREKAKKE 712

                          570
                   ....*....|....*...
gi 2024359632 2027 IDFLNSVIVDLQRRNEEL 2044
Cdd:PRK03918   713 LEKLEKALERVEELREKV 730
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 700-1441 9.03e-09

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 61.14  E-value: 9.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  700 LLEVTEEKEQTLENLKaKLESVEDQHLVEMEdtlnKLQEAEIKVSNLTKELQGKEQkllDLEKNLSAVNQVKDSLEKELQ 779
Cdd:TIGR00618  158 LKAKSKEKKELLMNLF-PLDQYTQLALMEFA----KKKSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELK 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  780 LLKEkftsavdgaenAQRAMQETINKLNQKEEQFALMSS---ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIA 856
Cdd:TIGR00618  230 HLRE-----------ALQQTQQSHAYLTQKREAQEEQLKkqqLLKQLRARIEELRAQEAVLEETQERINRARKAAP--LA 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  857 EIMKSSGDSSAQLMKMNDELRLKERQLEQI--QLELTKANEKAVQLQKNVEQTAQKAEQ------SQQETLKTHQEELKK 928
Cdd:TIGR00618  297 AHIKAVTQIEQQAQRIHTELQSKMRSRAKLlmKRAAHVKQQSSIEEQRRLLQTLHSQEIhirdahEVATSIREISCQQHT 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  929 MQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK--HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQ 1006
Cdd:TIGR00618  377 LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1007 AKSLSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKESLLSQHLEMESkiLLVQQDREELWTKNEELNSENKK 1086
Cdd:TIGR00618  457 EKIHLQESAQSLKERE-------QQLQTKEQIHLQETRKKAVVLARLLELQEEPC--PLCGSCIHPNPARQDIDNPGPLT 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1087 ILKQKEAAEAKSRQESTEKV-----ALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVAC 1161
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1162 QKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvSILTAERDSAQEKDLDLKSTHIALKnei 1241
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLASRQLALQ--- 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1242 dcllqtnrSLQSEKEMLLKSREELcvslantaneNQALKLRKDEMQTELETEREkLEKMTKDNMDLKASLSSLSNFLEEM 1321
Cdd:TIGR00618  684 --------KMQSEKEQLTYWKEML----------AQCQTLLRELETHIEEYDRE-FNEIENASSSLGSDLAAREDALNQS 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1322 KSSREASNSEKIHLLQEALFASEQRLLA------EREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFS 1395
Cdd:TIGR00618  745 LKELMHQARTVLKARTEAHFNNNEEVTAalqtgaELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCE 824

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1396 KSLQFEKHNEALLREKD----ELERKYSELLDEKKSLENAFSDMKREQEL 1441
Cdd:TIGR00618  825 TLVQEEEQFLSRLEEKSatlgEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 764-1018 9.13e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 9.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  764 LSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 843
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  844 LTEAKVKLENDIAEImkssgdssaqlmkmndeLRLKERQLEQIQLELTKANEKAVQLQKNVE--QTAQKAEQSQQETLKT 921
Cdd:COG4942     95 LRAELEAQKEELAEL-----------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  922 HQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1001
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233

                          250
                   ....*....|....*..
gi 2024359632 1002 KQAEQAKSLSSVLASAR 1018
Cdd:COG4942    234 AEAAAAAERTPAAGFAA 250
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1522-1879 9.98e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 9.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1522 DIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLV 1601
Cdd:COG1196    187 NLERLEDILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1602 QEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVhscvsvmLDELQHKYEVTEKEKMELVQEN 1681
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER-------LEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1682 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsegkhelLLEEMSNLALKLREIERLQAQ 1761
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE---------------LAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1762 TFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENK 1841
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350
                   ....*....|....*....|....*....|....*...
gi 2024359632 1842 KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELG 1879
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGL 522
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 352-857 1.01e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  352 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQ 431
Cdd:COG1196    284 EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAEAE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  432 LEEEKRKVEDLQFRVEEESitkGDLERKRQISEDPENTQTKLEhARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKS 511
Cdd:COG1196    360 LAEAEEALLEAEAELAEAE---EELEELAEELLEALRAAAELA-AQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  512 RIMELERDLALRVKEVAElrgrlesskhiddvdtslsLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKT 591
Cdd:COG1196    436 EEEEEEEALEEAAEEEAE-------------------LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  592 LSASNERMGKENESLKTKLDHANKENS---DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVK 668
Cdd:COG1196    497 LEAEADYEGFLEGVKAALLLAGLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRAT 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  669 LDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVsnLTK 748
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLRE--VTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  749 ELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLT 828
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500
                   ....*....|....*....|....*....
gi 2024359632  829 VMETKLKEREEREQQLTEAKVKLENDIAE 857
Cdd:COG1196    732 AEREELLEELLEEEELLEEEALEELPEPP 760
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1748-2026 1.35e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1748 LALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEE 1827
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1828 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKK 1907
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---EEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1908 SLPSNTLRESTLKKEIDE---ERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEE 1984
Cdd:COG1196    373 ELAEAEEELEELAEELLEalrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359632 1985 KVKNLEQKLKAKSEQPLTVTsPSGDIAANLLQDESAEDKQQE 2026
Cdd:COG1196    453 ELEEEEEALLELLAELLEEA-ALLEAALAELLEELAEAAARL 493
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
744-1307 1.57e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.57e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  744 SNLTKELQGKEQKllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQramqETINKLNQKEEQFALMSSELEQL 823
Cdd:PRK02224   190 DQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEAD----EVLEEHEERREELETLEAEIEDL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  824 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 903
Cdd:PRK02224   264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  904 VEQTAQKAEQSQQETlKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEAL 983
Cdd:PRK02224   344 AESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIE-ELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  984 KAAQKKNDELETQAEELKKQAEQAKSL----------SSVLASARKE-IELMSDKMRDLISEKETLAQERNTLKlEKESL 1052
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALleagkcpecgQPVEGSPHVEtIEEDRERVEELEAELEDLEEEVEEVE-ERLER 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1053 LSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQE 1132
Cdd:PRK02224   501 AEDLVEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1133 NDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD----LARNQRE 1208
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEarieEAREDKE 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1209 LLQE-VSILTAERDSAQEKDLDLKSTHIALKNEIDCLlqtnRSLQSEKEMLLKSREELcVSLANTANENQAL--KLRKDE 1285
Cdd:PRK02224   657 RAEEyLEQVEEKLDELREERDDLQAEIGAVENELEEL----EELRERREALENRVEAL-EALYDEAEELESMygDLRAEL 731

                          570       580
                   ....*....|....*....|..
gi 2024359632 1286 MQTELETerekLEKMTKDNMDL 1307
Cdd:PRK02224   732 RQRNVET----LERMLNETFDL 749
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1052-1895 2.14e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1052 LLSQHLEMESKILLVQQDREElwtkNEELNSENKKILKQKEAAEAKS----RQESTEKVALISEKSKLLSEIETAQADLL 1127
Cdd:pfam02463  125 LESQGISPEAYNFLVQGGKIE----IIAMMKPERRLEIEEEAAGSRLkrkkKEALKKLIEETENLAELIIDLEELKLQEL 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1128 KIT-QENDALRSSESTLLQQLKELQANKDAVDVACQKHIKE-REELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1205
Cdd:pfam02463  201 KLKeQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1206 QRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDE 1285
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1286 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKS--SREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTE 1363
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1364 KLTKATADAVLAETAFTEKINELNLEKESVF------SKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR 1437
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEdllketQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1438 EQELDFSAKRLLVQENTTLKYS---IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1514
Cdd:pfam02463  521 GGRIISAHGRLGDLGVAVENYKvaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1515 SFNTCSSDIEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1594
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVV-EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1595 TEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1674
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1675 MELVQ------------ENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRL--LVSEGKHEL 1740
Cdd:pfam02463  760 EEKEEekselslkekelAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkiKEEELEELA 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1741 LLEEMSNLALKLREIErlqaqTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQ 1820
Cdd:pfam02463  840 LELKEEQKLEKLAEEE-----LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632 1821 NNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEER 1895
Cdd:pfam02463  915 KENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEER 989
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 722-1467 2.53e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.53e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  722 EDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDlEKnlsavNQVKDSLEKELQLLKEKFTSAVDGAENAQR---A 798
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCE-EK-----NALQEQLQAETELCAEAEEMRARLAARKQEleeI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  799 MQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL 878
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  879 KERQLEQIQLELTKANEKAVQLQK----------NVEQTAQKAEQSQQETLKTHqeelKKMQDQLTDMKKQMETSQNQYK 948
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKlknkheamisDLEERLKKEEKGRQELEKAK----RKLEGESTDLQEQIAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  949 DLQAKYEKETSEMITkhdadikgfKQNLLDAEEALK-AAQKKNDELETQAEELKKQAEQAKslssvlaSARKEIElmsdk 1027
Cdd:pfam01576  233 ELRAQLAKKEEELQA---------ALARLEEETAQKnNALKKIRELEAQISELQEDLESER-------AARNKAE----- 291

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1028 mrdliSEKETLAQERNTLKLEKESLLSQhlemeskillvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEK-V 1106
Cdd:pfam01576  292 -----KQRRDLGEELEALKTELEDTLDT-----------TAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKhT 355

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1107 ALISEKSKLLSEIETAQADLLKITQendALRSSESTLLQQLKELQANKDAVDvacQKHIKEREELEHYQKLLEENDRVIK 1186
Cdd:pfam01576  356 QALEELTEQLEQAKRNKANLEKAKQ---ALESENAELQAELRTLQQAKQDSE---HKRKKLEGQLQELQARLSESERQRA 429

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1187 DKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKdldLKSTHIALKNEIDCLLQTN---RSLQSEKEMLLKSRE 1263
Cdd:pfam01576  430 ELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ---LQDTQELLQEETRQKLNLStrlRQLEDERNSLQEQLE 506

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1264 ELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFAS 1343
Cdd:pfam01576  507 EEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL 586

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1344 EQrlLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLD 1423
Cdd:pfam01576  587 VD--LDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRA 664

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 2024359632 1424 EKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEEL 1467
Cdd:pfam01576  665 EMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
353-952 2.89e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 2.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE--------ELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  433 EEEKRKVEDLQfrvEEESITKGDLERKRQISEDPEntqtklehARIKELEqsllfekTKADKLQRELEDTRV---ATVSE 509
Cdd:PRK02224   282 RDLRERLEELE---EERDDLLAEAGLDDADAEAVE--------ARREELE-------DRDEELRDRLEECRVaaqAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  510 KSRIMELERDLALRVKEVAELRGRLESskhiddvdtslsllqEISSLQEKMaaagkehqremsslkEKFESSEEALRKEI 589
Cdd:PRK02224   344 AESLREDADDLEERAEELREEAAELES---------------ELEEAREAV---------------EDRREEIEELEEEI 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  590 KTLSASNERMGKENESLKTKLDHANKENSDVIELWKSkLESAIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkl 669
Cdd:PRK02224   394 EELRERFGDAPVDLGNAEDFLEELREERDELREREAE-LEATLRTARERVEEAEALLEAGKCPECG-------------- 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  670 dyenemsnlklkQENEKSQHLKEIEALKAKLLEVTEEKEQ---TLENLKAKLESVEDqhLVEMEDTLNKLQEaeiKVSNL 746
Cdd:PRK02224   459 ------------QPVEGSPHVETIEEDRERVEELEAELEDleeEVEEVEERLERAED--LVEAEDRIERLEE---RREDL 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  747 TKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQllkEKFTSAVDGAENAQRAmQETINKLNQKEEQFALMSSELEQLKSN 826
Cdd:PRK02224   522 EELIAERRETIEEKRERAEELRERAAELEAEAE---EKREAAAEAEEEAEEA-REEVAELNSKLAELKERIESLERIRTL 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  827 LTVMETKLKEREEREQQLtEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQ---------LEQIQLELTKANEKA 897
Cdd:PRK02224   598 LAAIADAEDEIERLREKR-EALAELNDERRERLAEKRERKRELEAEFDEARIEEARedkeraeeyLEQVEEKLDELREER 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  898 VQLQKNVeqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 952
Cdd:PRK02224   677 DDLQAEI--GAVENELEELEELRERREALENRVEALEALYDEAEELESMYGDLRA 729
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 686-1563 3.26e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.03  E-value: 3.26e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  686 KSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLEsvedQHLVEMEDtlnKLQEAEIKVSNLTKELQGKEQKLLDLEKNLS 765
Cdd:pfam01576   69 RKQELEEILHELESRLEEEEERSQQLQNEKKKMQ----QHIQDLEE---QLDEEEAARQKLQLEKVTTEAKIKKLEEDIL 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  766 AVNQVKDSLEKELQLLKEKftsavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLT 845
Cdd:pfam01576  142 LLEDQNSKLSKERKLLEER--------------ISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELE 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  846 EAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV-EQTAQKAEqsQQETLKTHQE 924
Cdd:pfam01576  208 KAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIrELEAQISE--LQEDLESERA 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  925 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQA-EELKKQ 1003
Cdd:pfam01576  286 ARNKAEKQRRDLGEELEALKTELEDTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1004 AEQAKSLSSVLASARKEIElmsDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSE 1083
Cdd:pfam01576  365 LEQAKRNKANLEKAKQALE---SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSE 441

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1084 ------------NKKILKQKEAAEAKSR---------QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSEST 1142
Cdd:pfam01576  442 lesvssllneaeGKNIKLSKDVSSLESQlqdtqellqEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLST 521

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1143 LLQQL----KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL-- 1216
Cdd:pfam01576  522 LQAQLsdmkKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLek 601

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1217 -------------------TAERDSAQEKDLDLKSTHIALKNEIDCLL-------QTNRSLQSEKEMLLKSREELCVSLA 1270
Cdd:pfam01576  602 kqkkfdqmlaeekaisaryAEERDRAEAEAREKETRALSLARALEEALeakeeleRTNKQLRAEMEDLVSSKDDVGKNVH 681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1271 NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAE 1350
Cdd:pfam01576  682 ELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDE 761

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1351 R-------------EELVNENKAVTEKLTKATADAV-------LAETAFTEKINELNLEKESVFSKSLQFEKHNEALLRE 1410
Cdd:pfam01576  762 RkqraqavaakkklELDLKELEAQIDAANKGREEAVkqlkklqAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAE 841

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1411 KDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLeNQELiacrsdLSDLLKE 1490
Cdd:pfam01576  842 LLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS-NTEL------LNDRLRK 914

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359632 1491 AQDARRTLENELAAVSHAKQVLSSSFNTcssdieiLNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1563
Cdd:pfam01576  915 STLQVEQLTTELAAERSTSQKSESARQQ-------LERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLE 980
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 615-1922 4.78e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 58.91  E-value: 4.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  615 KENSDVIELWKSKLESAIASHQQAMEELKVSFN----KGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENEKSQHL 690
Cdd:TIGR01612  503 KDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKaklyKEIEAGLKESYELAKNWKKLIHEI-----KKELEEENEDSIHL 577

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  691 -KEIEALKAKLLEVTEE----KEQTLEnLKAKLESVEDQH-LVEMEDTLNKLQE---------AEIKVSNLTKELQGKEQ 755
Cdd:TIGR01612  578 eKEIKDLFDKYLEIDDEiiyiNKLKLE-LKEKIKNISDKNeYIKKAIDLKKIIEnnnayidelAKISPYQVPEHLKNKDK 656

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  756 KLLDLEKNLSAVNQVK-DSLEKELQLLKEKftSAVDGAENAQRA--MQETINKLNQKeeqfaLMSSELEQLKSNLTVMET 832
Cdd:TIGR01612  657 IYSTIKSELSKIYEDDiDALYNELSSIVKE--NAIDNTEDKAKLddLKSKIDKEYDK-----IQNMETATVELHLSNIEN 729

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  833 KlkereereqqlteaKVKLENDIAEIMKS-SGDSSAQLMKMNDELRLKERQL---------EQIQLELTKANEKAVQLQK 902
Cdd:TIGR01612  730 K--------------KNELLDIIVEIKKHiHGEINKDLNKILEDFKNKEKELsnkindyakEKDELNKYKSKISEIKNHY 795

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  903 N---------VEQTAQKAEQSQQ--ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKET-------SEMITK 964
Cdd:TIGR01612  796 NdqinidnikDEDAKQNYDKSKEyiKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEKIdseheqfAELTNK 875

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  965 HDADIKG-----FKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslssVLASARKEIELMSDKMRDLiseKETLA 1039
Cdd:TIGR01612  876 IKAEISDdklndYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIK----ICENTKESIEKFHNKQNIL---KEILN 948

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1040 QERNTLKLEKESLLSQHLEMESKILLVQQDREELWT---------KNEEL----NSENKKILKQKEAAEAKSRQESTEKV 1106
Cdd:TIGR01612  949 KNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKdaslndyeaKNNELikyfNDLKANLGKNKENMLYHQFDEKEKAT 1028

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1107 ALISEKS----KLLSEIETA-QADLLKITQENDAL--RSSESTLLQQLKELQANkdavdVACQKHIKEREELEHYQKLLE 1179
Cdd:TIGR01612 1029 NDIEQKIedanKNIPNIEIAiHTSIYNIIDEIEKEigKNIELLNKEILEEAEIN-----ITNFNEIKEKLKHYNFDDFGK 1103

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1180 ENDrvIKDKDDViqrlQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMll 1259
Cdd:TIGR01612 1104 EEN--IKYADEI----NKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEEIEKKI-- 1175

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1260 ksrEELCVSLANTANENQALKLRKDEMqTELETEREKLEKMTKDNMDLKASLSSLsnFLEEMKSSREASnsekihllqEA 1339
Cdd:TIGR01612 1176 ---ENIVTKIDKKKNIYDEIKKLLNEI-AEIEKDKTSLEEVKGINLSYGKNLGKL--FLEKIDEEKKKS---------EH 1240

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1340 LFASEQRLLAEREELvnenkavtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEAL--LREKD----E 1413
Cdd:TIGR01612 1241 MIKAMEAYIEDLDEI--------KEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENIsdIREKSlkiiE 1312

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1414 LERKYSELLDEKKSLENAFSDMKREQeldfSAKRLLVQENTTLkYSIEALEeelKKKNLENQeliacrsdLSDLLKEAQD 1493
Cdd:TIGR01612 1313 DFSEESDINDIKKELQKNLLDAQKHN----SDINLYLNEIANI-YNILKLN---KIKKIIDE--------VKEYTKEIEE 1376

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1494 ARRTLENELAAVSHAKQVL--SSSFNTCSSDIEilnrerTELQDKcqKLTGEVENMKENltvekKARILDKES----FLL 1567
Cdd:TIGR01612 1377 NNKNIKDELDKSEKLIKKIkdDINLEECKSKIE------STLDDK--DIDECIKKIKEL-----KNHILSEESnidtYFK 1443

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1568 ERMELQNNIGFLEKEVEEMREKNKEFLTEKE------------LLVQEKEKSETKLEEVIKEKmilyKETEQLASKIEQL 1635
Cdd:TIGR01612 1444 NADENNENVLLLFKNIEMADNKSQHILKIKKdnatndhdfninELKEHIDKSKGCKDEADKNA----KAIEKNKELFEQY 1519

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1636 KSDFTSLSVSKAELedvhscvsvmldELQHKYEVTEKEKMELVQENESLHaewKSLVIINEEILKEKEKLSKEYYKLHEK 1715
Cdd:TIGR01612 1520 KKDVTELLNKYSAL------------AIKNKFAKTKKDSEIIIKEIKDAH---KKFILEAEKSEQKIKEIKKEKFRIEDD 1584

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1716 VVALLEQTDADFSCRLLVSEGKHELLleEMSNLALK----LREIERLQAQ-------TFMQKFEADKRAEEVLQT-MEKV 1783
Cdd:TIGR01612 1585 AAKNDKSNKAAIDIQLSLENFENKFL--KISDIKKKindcLKETESIEKKissfsidSQDTELKENGDNLNSLQEfLESL 1662

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1784 TKEKDAIHQEKIEtlasLENSRQTNEKLQNELDMLKQN------------NLKNEEELTKSKELLnleNKKVEELKKEFE 1851
Cdd:TIGR01612 1663 KDQKKNIEDKKKE----LDELDSEIEKIEIDVDQHKKNyeigiiekikeiAIANKEEIESIKELI---EPTIENLISSFN 1735

                         1370      1380      1390      1400      1410      1420      1430
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1852 ALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKE 1922
Cdd:TIGR01612 1736 TNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKEPITYDEIKNTRINAQNEFLKIIEIEKK 1806
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
797-1218 5.52e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  797 RAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEIMKSSGDSSAQLMKMNDEL 876
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  877 RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEK 956
Cdd:COG4717    152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  957 ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVL--------ASARKEIELMSDKM 1028
Cdd:COG4717    232 LENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLflllarekASLGKEAEELQALP 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1029 RDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK--EAAEAKSRQESTEKV 1106
Cdd:COG4717    312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1107 ALISEKSKLLSEIETAQADLLKITQENDALRS--SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRv 1184
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE- 470

                          410       420       430
                   ....*....|....*....|....*....|....
gi 2024359632 1185 ikdkddvIQRLQSSYDDLARNQRELLQEVSILTA 1218
Cdd:COG4717    471 -------LAELLQELEELKAELRELAEEWAALKL 497
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2119-2135 7.60e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.60e-08
                           10
                   ....*....|....*..
gi 2024359632 2119 RPYCDTCEMFGHWTADC 2135
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 874-1072 8.73e-08

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 56.76  E-value: 8.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  874 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDlQAK 953
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQAEIAEAEAEIEERREELGE-RAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  954 YEKETSEMITKHDA-----DIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1028
Cdd:COG3883     94 ALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359632 1029 RDLISEKE----TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREE 1072
Cdd:COG3883    174 EAQQAEQEallaQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 406-1476 9.85e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 57.75  E-value: 9.85e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  406 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQ----------FRVEEESITKGDL-----ERKRQISEDPENTQ 470
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEkeikdlfdkyLEIDDEIIYINKLklelkEKIKNISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  471 TKLEHARIKELEQSLLFEKTKADKLQ----RELEDTRVATV-SEKSRIME-----LERDLALRVKEVAelRGRLESSKHI 540
Cdd:TIGR01612  621 KAIDLKKIIENNNAYIDELAKISPYQvpehLKNKDKIYSTIkSELSKIYEddidaLYNELSSIVKENA--IDNTEDKAKL 698

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  541 DDVDTSLSllQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEI-----KTLSASNERMGKENESLKTKLDHANK 615
Cdd:TIGR01612  699 DDLKSKID--KEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIhgeinKDLNKILEDFKNKEKELSNKINDYAK 776

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  616 ENsDVIELWKSKLesaiashqqamEELKVSFNKGVGAQTAEFAELKTQMEKVKlDYENEMSnlklKQENEKSQHLKEIEA 695
Cdd:TIGR01612  777 EK-DELNKYKSKI-----------SEIKNHYNDQINIDNIKDEDAKQNYDKSK-EYIKTIS----IKEDEIFKIINEMKF 839

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  696 LKAKLLEVTEEKEQTLENLKAKLESVEDQhlveMEDTLNKLQeAEIkvsnltkelqgKEQKLLDLEKNL----SAVNQVK 771
Cdd:TIGR01612  840 MKDDFLNKVDKFINFENNCKEKIDSEHEQ----FAELTNKIK-AEI-----------SDDKLNDYEKKFndskSLINEIN 903

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  772 DSLEKELQLLKEkfTSAVDGAENAQRAMQETINKLNQKEEQFAlmsselEQLKSNL-TVMETKLKEREEREQ---QLTEA 847
Cdd:TIGR01612  904 KSIEEEYQNINT--LKKVDEYIKICENTKESIEKFHNKQNILK------EILNKNIdTIKESNLIEKSYKDKfdnTLIDK 975

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  848 KVKLENDIAEIMKSSGDS-SAQLMKMNDELRL-----KERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 921
Cdd:TIGR01612  976 INELDKAFKDASLNDYEAkNNELIKYFNDLKAnlgknKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYN 1055

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  922 HQEEL-----KKMQDQLTDMKKQMETSQNQYKDLQAKYE-------------KETSEmITKHDADIKGFKQ----NLLDA 979
Cdd:TIGR01612 1056 IIDEIekeigKNIELLNKEILEEAEINITNFNEIKEKLKhynfddfgkeeniKYADE-INKIKDDIKNLDQkidhHIKAL 1134

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  980 EEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMS---------DKMRDLISEKETLAQERNTL----- 1045
Cdd:TIGR01612 1135 EEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTkidkkkniyDEIKKLLNEIAEIEKDKTSLeevkg 1214

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1046 ---------------KLEKESLLSQHL--EMESKIllvqQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVAL 1108
Cdd:TIGR01612 1215 inlsygknlgklfleKIDEEKKKSEHMikAMEAYI----EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHH 1290

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1109 ISEKS--KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK-----------HIKE-REELEHY 1174
Cdd:TIGR01612 1291 IISKKhdENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEianiynilklnKIKKiIDEVKEY 1370

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1175 QKLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS 1253
Cdd:TIGR01612 1371 TKEIEENNKNIKDELDKSEKLiKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNE 1450

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1254 EKEMLLKSREelcvsLANTANEnQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKI 1333
Cdd:TIGR01612 1451 NVLLLFKNIE-----MADNKSQ-HILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVT 1524

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1334 HLLQEalfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREK-- 1411
Cdd:TIGR01612 1525 ELLNK---YSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQls 1601

                         1130      1140      1150      1160      1170      1180      1190
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 1412 -DELERKYSELLDEKKSLENAFSDM----KREQELDFSAKRLLVQENTTLKYSIEALEEELK--KKNLENQE 1476
Cdd:TIGR01612 1602 lENFENKFLKISDIKKKINDCLKETesieKKISSFSIDSQDTELKENGDNLNSLQEFLESLKdqKKNIEDKK 1673
PTZ00121 PTZ00121
MAEBL; Provisional
 1318-1991 1.05e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.05e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1318 LEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAfTEKINELNLEKESVFSKS 1397
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKA 1292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1398 LQFEKHNEAL----LREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLE 1473
Cdd:PTZ00121  1293 DEAKKAEEKKkadeAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1474 NQEliaCRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTV 1553
Cdd:PTZ00121  1373 KEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1554 EKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-----KNKEFLTEKELLVQEKEKSETKLEEVIKEKMilYKETEQL 1628
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1629 ASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK----MELVQENESLHAEWKSLVIINEEILKEKEK 1704
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1705 LSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVT 1784
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1785 KEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQL 1864
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1865 AALQEENVKLAEELGRSRDEVTSHQKLEEERSVlnNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQK 1944
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359632 1945 DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQ 1991
Cdd:PTZ00121  1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK 1892
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 427-1265 2.38e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.21  E-value: 2.38e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  427 ELLNQLEEEKRKVED-LQFRVEEESITKGDLERKRQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVA 505
Cdd:TIGR00606  210 KYLKQYKEKACEIRDqITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  506 TVSEKSRIMELErdlalRVKEVAELRGRLESSKHiddvdtslsllQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEAL 585
Cdd:TIGR00606  290 LKMEKVFQGTDE-----QLNDLYHNHQRTVREKE-----------RELVDCQRELEKLNKE-RRLLNQEKTELLVEQGRL 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  586 RKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwksKLESAIASHQQAMEELKVSFNKGVgaqtAEFAELKTQME 665
Cdd:TIGR00606  353 QLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSER---QIKNFHTLVIERQEDEAKTAAQLC----ADLQSKERLKQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  666 KVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEvteekeqtLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKV 743
Cdd:TIGR00606  426 EQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKE--------LQQLEGSSDRIleLDQELRKAERELSKAEKNSLTE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  744 SNLTKELQGKEQKlLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSElEQL 823
Cdd:TIGR00606  498 TLKKEVKSLQNEK-ADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNK-KQL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  824 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDEL------RLKERQLEQIQLELTKANEKA 897
Cdd:TIGR00606  576 EDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQR 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  898 VQLQKNVEQTAQKAEQSQQETLK---------THQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDAd 968
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSccpvcqrvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPG- 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  969 ikgfKQNLLD-AEEALKAAQKKNDELETQAEELKKQAEQAKSLssvLASARKEIELMSDKMRDL-ISEKETLAQERNTLK 1046
Cdd:TIGR00606  735 ----RQSIIDlKEKEIPELRNKLQKVNRDIQRLKNDIEEQETL---LGTIMPEEESAKVCLTDVtIMERFQMELKDVERK 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1047 LEKESLLSQHLEMESKILLVQQDREE-------LWTKNEELNSENKKILKQKEAAEAKSRQESTEKVAL---ISEKSKLL 1116
Cdd:TIGR00606  808 IAQQAAKLQGSDLDRTVQQVNQEKQEkqheldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIgtnLQRRQQFE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1117 SEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDavDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQ 1196
Cdd:TIGR00606  888 EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKE--ELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ 965

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 1197 SSYDDLARNQRELLQEVSILTAERDSAQEK---DLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREEL 1265
Cdd:TIGR00606  966 DGKDDYLKQKETELNTVNAQLEECEKHQEKineDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEEL 1037
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
694-1151 2.39e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  694 EALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 773
Cdd:COG4717     41 AFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  774 LEKELQLlkekftsavdgaenaqramQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEn 853
Cdd:COG4717    121 LEKLLQL-------------------LPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELE- 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  854 diAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE-QSQQETLKTHQEELK----- 927
Cdd:COG4717    181 --ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEaAALEERLKEARLLLLiaaal 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  928 -----------------------------KMQDQLTDMKKQMETSQNQYKDLQAKY---EKETSEMITKHDADIKGFKQN 975
Cdd:COG4717    259 lallglggsllsliltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEeleEEELEELLAALGLPPDLSPEE 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  976 LLDAEEALKAAQKKNDELETQAEELKKQ---AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL 1052
Cdd:COG4717    339 LLELLDRIEELQELLREAEELEEELQLEeleQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL 418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1053 LSQHLEMESKILlvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKvalisEKSKLLSEIETAQADLLKITQE 1132
Cdd:COG4717    419 EELLEALDEEEL--EEELEELEEELEELEEELEELREELAELEAELEQLEEDG-----ELAELLQELEELKAELRELAEE 491

                          490
                   ....*....|....*....
gi 2024359632 1133 NDALRSSESTLLQQLKELQ 1151
Cdd:COG4717    492 WAALKLALELLEEAREEYR 510
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
969-1593 2.68e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 2.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  969 IKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdKMRDLISEKETLAQERNTLKLE 1048
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELE----KLEKEVKELEELKEEIEELEKE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1049 KESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEA--KSRQESTEKVALISEKSKLLSEIETAQADL 1126
Cdd:PRK03918   247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1127 LKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhIKEREELEHYQKLLEENDRVIKDK--DDVIQRLQSSYDDLAR 1204
Cdd:PRK03918   327 EERIKELEEKEERLEELKKKLKELEKRLEE--------LEERHELYEEAKAKKEELERLKKRltGLTPEKLEKELEELEK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1205 NQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKsrEELCVSLANTANENQALklrkD 1284
Cdd:PRK03918   399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELL--EEYTAELKRIEKELKEI----E 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1285 EMQTELETEREKLEKMTKDNMDLkASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVtek 1364
Cdd:PRK03918   473 EKERKLRKELRELEKVLKKESEL-IKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL--- 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1365 ltkatadavlaetaftEKINELNLEKesvfskslqfekhnEALLREKDELERKYSELLDEKKSLenAFSDMKrEQELDFS 1444
Cdd:PRK03918   549 ----------------EKLEELKKKL--------------AELEKKLDELEEELAELLKELEEL--GFESVE-ELEERLK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1445 AKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAK-QVLSSSFNTCSSDI 1523
Cdd:PRK03918   596 ELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyEELREEYLELSREL 675

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1524 EILNRERTELQDKCQKLTGEVENMKENLTVEKKARildKESFLLERMelqnnigflEKEVEEMREKNKEF 1593
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEELEEREKAK---KELEKLEKA---------LERVEELREKVKKY 733
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 908-1152 3.08e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 3.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  908 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAAQ 987
Cdd:COG4942     19 ADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKALLKQLAALERR--------IAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  988 KKNDELETQAEELKKQ-AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhlemeskillv 1066
Cdd:COG4942     90 KEIAELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL-------------- 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1067 QQDREELWTKNEELNSEnkkiLKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQ 1146
Cdd:COG4942    156 RADLAELAALRAELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELA---ELAAELAELQQEAEELEAL 228


                   ....*.
gi 2024359632 1147 LKELQA 1152
Cdd:COG4942    229 IARLEA 234
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1758-2072 3.64e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.85  E-value: 3.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1758 LQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqeKIETLASLENSRQ-------TNEKLQNELDMLKQNNLKNEEELT 1830
Cdd:COG5022    765 LQALKRIKKIQVIQHGFRLRRLVDYELKWRLFI---KLQPLLSLLGSRKeyrsylaCIIKLQKTIKREKKLRETEEVEFS 841

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1831 KSKELLNLENKKVEELKKEFEALKlaaaqKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1910
Cdd:COG5022    842 LKAEVLIQKFGRSLKAKKRFSLLK-----KETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLS 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1911 SNTLRESTLKKEID--EERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKN 1988
Cdd:COG5022    917 SDLIENLEFKTELIarLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKN 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1989 LEQKLKAKSEQPLTVTSPSGDiaANLLQDESAEdKQQEIDFLNSVIVDLQRRNEELNLKiqRMCEAALNGNEEETINYDS 2068
Cdd:COG5022    997 FKKELAELSKQYGALQESTKQ--LKELPVEVAE-LQSASKIISSESTELSILKPLQKLK--GLLLLENNQLQARYKALKL 1071


                   ....
gi 2024359632 2069 EEEG 2072
Cdd:COG5022   1072 RREN 1075
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 353-1195 3.91e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 3.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  353 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdgHDRHVLEMEAKMDQLRAMVEAADREKVELLNQL 432
Cdd:pfam02463  186 AELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLD--YLKLNEERIDLLQELLRDEQEEIESSKQEIEKE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  433 EEEKRKVedLQFRVEEESITKGDLERKRQISEDPENTQTKLEHA--RIKELEQSLLFEKTKADKLQRELEDTRVATVSEK 510
Cdd:pfam02463  264 EEKLAQV--LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLerRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  511 SRIMELERDLALRVKEVAELRGRLEsskhiddvdtslsllQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIK 590
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQE---------------KLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  591 TLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVgAQTAEFAELKTQMEKVKLD 670
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELE-LKKSEDLLKETQLVKLQEQ 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  671 YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKEL 750
Cdd:pfam02463  486 LELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQK 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  751 QGKEQKLLDLEKNlSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM 830
Cdd:pfam02463  566 LVRALTELPLGAR-KLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  831 ETKLKEREEREQQLTE-AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 909
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEkSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  910 KAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKK 989
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  990 NDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQD 1069
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1070 REELWTKNEELNsENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKitQENDALRSSESTLLQQLKE 1149
Cdd:pfam02463  885 KDELESKEEKEK-EEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLL--EEADEKEKEENNKEEEEER 961

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1150 LQANKDAVDVACQKHIKEREE----LEHYQKLLEENDRVIKDKDDVIQRL 1195
Cdd:pfam02463  962 NKRLLLAKEELGKVNLMAIEEfeekEERYNKDELEKERLEEEKKKLIRAI 1011
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 336-964 6.65e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 54.73  E-value: 6.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  336 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDqlr 415
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  416 amVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKrqisedpentqTKLEHARIKELEQsllfektKADKL 495
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEK-----------TKLQDENLKELIE-------KKDHL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  496 QRELEDTRVATVSEKSRIMELERDLALRVKEVAEL------------RGRLESSKHIDDVDTSLSLLQE--------ISS 555
Cdd:pfam05483  295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLteekeaqmeelnKAKAAHSFVVTEFEATTCSLEEllrteqqrLEK 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  556 LQEKMAAAGKEHQREMSSLKE--KFESSEEALRKEIKTLSASNERMGKENESLK-------------TKLDHANKENSDV 620
Cdd:pfam05483  375 NEDQLKIITMELQKKSSELEEmtKFKNNKEVELEELKKILAEDEKLLDEKKQFEkiaeelkgkeqelIFLLQAREKEIHD 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  621 IELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAEL-KTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAK 699
Cdd:pfam05483  455 LEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCdKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLK 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  700 LLEVTEEKEQtleNLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLL-------DLEKNLSAVNQVKD 772
Cdd:pfam05483  535 QIENLEEKEM---NLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKilenkcnNLKKQIENKNKNIE 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  773 SLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLE 852
Cdd:pfam05483  612 ELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQ 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  853 NDIaeimkssgdssaqlmkmndELRLKERQLEQIQL-ELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQE-ELKKMQ 930
Cdd:pfam05483  692 KEI-------------------DKRCQHKIAEMVALmEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNIK 752

                          650       660       670
                   ....*....|....*....|....*....|....
gi 2024359632  931 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 964
Cdd:pfam05483  753 AELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
PRK11281 PRK11281
mechanosensitive channel MscK;
705-1154 9.92e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.15  E-value: 9.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  705 EEKEQTLENL-KAKLESVED----QHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAvnqvkdslekelq 779
Cdd:PRK11281    39 ADVQAQLDALnKQKLLEAEDklvqQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA------------- 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  780 lLKEKFTSAVDgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETklkeREEREQ-QLTEAKVKLEnDIAEI 858
Cdd:PRK11281   106 -LKDDNDEETR-ETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQT----QPERAQaALYANSQRLQ-QIRNL 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  859 MKSSGDSSAQL-----MKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKkmQDQL 933
Cdd:PRK11281   179 LKGGKVGGKALrpsqrVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQ-LQLLQEAIN--SKRL 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  934 TDMKKQMETSQNQykdlQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKN-------DELeTQAEELKKqaEQ 1006
Cdd:PRK11281   256 TLSEKTVQEAQSQ----DEAARIQANPLVAQELEINLQLSQRLLKATEKLNTLTQQNlrvknwlDRL-TQSERNIK--EQ 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1007 AKSLSSVLASAR------------KEIELMSDKMRDLISEKETLAQERNTLklekeSLLSQHLEMeskilLVQQDreelw 1074
Cdd:PRK11281   329 ISVLKGSLLLSRilyqqqqalpsaDLIEGLADRIADLRLEQFEINQQRDAL-----FQPDAYIDK-----LEAGH----- 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1075 tkNEELNSENKKILKQKeaaeAKSRQESTEKvaLISEKSKLLSEIETAQADLLKITQENDALRsseSTLLQQLKELQANK 1154
Cdd:PRK11281   394 --KSEVTDEVRDALLQL----LDERRELLDQ--LNKQLNNQLNLAINLQLNQQQLLSVSDSLQ---STLTQQIFWVNSNK 462
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 354-633 9.98e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.29  E-value: 9.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  354 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQLE 433
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN----EEAANLRERLESLERRIAATERRLEDLEEQIE 848

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  434 EEKRKVEDLQFRVEEESITKGDLERKRQISEDpentqtklEHARIKELEQSLLFEKTKADKLQRELEdtrvatvsekSRI 513
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLN--------ERASLEEALALLRSELEELSEELRELE----------SKR 910

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  514 MELERDLALRVKEVAELRGRLEsskhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLS 593
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLE------------GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359632  594 ASNERMGKEN-------ESLKTKLDHANKENSDVIELwKSKLESAIA 633
Cdd:TIGR02168  979 NKIKELGPVNlaaieeyEELKERYDFLTAQKEDLTEA-KETLEEAIE 1024
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1460-2010 1.10e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1460 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSH---AKQVLSSSFNTCSSDIEILNRERTELQDK 1536
Cdd:TIGR04523  147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkllKLELLLSNLKKKIQKNKSLESQISELKKQ 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1537 CQKLTGEVENMKENLtVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEkekSETKLEEVIK 1616
Cdd:TIGR04523  227 NNQLKDNIEKKQQEI-NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQ---LKSEISDLNN 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1617 EKMilyketeqlASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINE 1696
Cdd:TIGR04523  303 QKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1697 EILKEKEKLSKEYYKLHEKVVALLEQtdadFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEE- 1775
Cdd:TIGR04523  374 KLKKENQSYKQEIKNLESQINDLESK----IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQd 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1776 -VLQTMEKVTKEKDAIHQEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEAL 1853
Cdd:TIGR04523  450 sVKELIIKNLDNTRESLETQLKVLsRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1854 KLAAAQKSQQLAALQEENVKLAEELGRSrdevtshqKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEerasLQKS 1933
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKKE--------NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ----KEKE 597

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632 1934 ISDTSALITQKDEELEKLRNEITVLRGENasaktlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDI 2010
Cdd:TIGR04523  598 KKDLIKEIEEKEKKISSLEKELEKAKKEN----------EKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEI 664
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1455-1977 1.61e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1455 TLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLEnelaavshakqVLSSSFNTCSSDIEILNRERTELQ 1534
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-----------TLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1535 DKCQKLTGEVENMKENLT---VEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKL 1611
Cdd:PRK02224   279 EEVRDLRERLEELEEERDdllAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1612 EEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSL 1691
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1692 viinEEILKEKEKLskeyykLHEKVVALLEQT--DADFSCRLLVSEGKHELLLEEMSNLALKLREIE-RLQAQTFMQKFE 1768
Cdd:PRK02224   439 ----RERVEEAEAL------LEAGKCPECGQPveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEeRLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1769 AD-KRAEEVLQTMEKVTKEKDAIHQEKIETLASLensRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1847
Cdd:PRK02224   509 DRiERLEERREDLEELIAERRETIEEKRERAEEL---RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELK 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1848 KEFEALK------LAAAQKSQQLAALQEENVKLAEELGRSRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRES 1917
Cdd:PRK02224   586 ERIESLErirtllAAIADAEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQV 665

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1918 TLK-KEIDEERASLQKSIsdtsALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLES 1977
Cdd:PRK02224   666 EEKlDELREERDDLQAEI----GAVENELEELEELRERREALENRVEALEALYDEAEELES 722
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
926-1476 2.32e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 2.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  926 LKKMQDQLTDMKKQMEtsQNQYKDLQAK---YEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1002
Cdd:PRK02224   182 LSDQRGSLDQLKAQIE--EKEEKDLHERlngLESELAEL----DEEIERYEEQREQARETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1003 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL-------KLEKESLLSQHLEMESKILLVQQDREELWT 1075
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1076 KNEELNSENKKILkqKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQADLLKITQENDALRSsestllqqlkELQANKD 1155
Cdd:PRK02224   336 AAQAHNEEAESLR--EDADDLEERAEELR-----EEAAELESELEEAREAVEDRREEIEELEE----------EIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1156 AVDVACQkhikEREELEHYQKLLEEN-DRVIKDKDDVIQRLQSSYDDLARNQR--------ELLQEVS----ILTAERDS 1222
Cdd:PRK02224   399 RFGDAPV----DLGNAEDFLEELREErDELREREAELEATLRTARERVEEAEAlleagkcpECGQPVEgsphVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1223 AQEKDL-----DLKSTHIALKNEIDcLLQTNRSLQSEKEMLLKSRE---ELCVSLANTANEN----QALKLRKDEMQTEL 1290
Cdd:PRK02224   475 ERVEELeaeleDLEEEVEEVEERLE-RAEDLVEAEDRIERLEERREdleELIAERRETIEEKreraEELRERAAELEAEA 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1291 ETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNS-EKIHLLQEALFASEQRLLAEREELVNENKAVTEKL-TKA 1368
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREKREALAELNDERRERLaEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1369 TADAVLAETAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-EQELDFSAKR 1447
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAREDKE-------RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElRERREALENR 706

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2024359632 1448 L-----LVQENTTLKYSIEALEEELKKKNLENQE 1476
Cdd:PRK02224   707 VealeaLYDEAEELESMYGDLRAELRQRNVETLE 740
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1320-1999 3.28e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.66  E-value: 3.28e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1320 EMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS-- 1397
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkk 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1398 -------------LQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE----QELDFSAKRLLVQENTTLKYSI 1460
Cdd:TIGR00618  259 qqllkqlrarieeLRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIhtelQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1461 EALEEELKKKNLENQE-LIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRErtelQDKCQK 1539
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEiHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1540 LTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK---EKSETKLEEVIK 1616
Cdd:TIGR00618  415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1617 EKMILYKETEQLASKIEQLKSDFTSLSVSKA------ELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKS 1690
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1691 LVIINEEILKEKEKLSKEyyklhekVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEAD 1770
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNI-------TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1771 KRAEEVLQTMEKVTKEKDAIHQEKIETLASlensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEF 1850
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLAS-------RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1851 EALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKeidEERASL 1930
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN---RLREED 797

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1931 QKSISDTSALITQK--DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 1999
Cdd:TIGR00618  798 THLLKTLEAEIGQEipSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQ 868
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 728-921 3.51e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 51.75  E-value: 3.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  728 EMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN 807
Cdd:COG3883     24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  808 QKEeqFALMSSELEQLKSNLTVMET-------KLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKE 880
Cdd:COG3883    104 YLD--VLLGSESFSDFLDRLSALSKiadadadLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQE 181

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2024359632  881 RQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 921
Cdd:COG3883    182 ALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
661-1202 3.57e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.57e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  661 KTQMEKVKLDYENEMSNLKLKQENEKSQHLKE-IEALKAKLLEVTEEKE----------QTLENLKAKLESVED--QHLV 727
Cdd:PRK02224   175 RLGVERVLSDQRGSLDQLKAQIEEKEEKDLHErLNGLESELAELDEEIEryeeqreqarETRDEADEVLEEHEErrEELE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  728 EMEDTLNKLQ----EAEIKVSNLTKELQGKEQKLLDLEKNLS--------------AVNQVKDSLEKEL----QLLKEKF 785
Cdd:PRK02224   255 TLEAEIEDLRetiaETEREREELAEEVRDLRERLEELEEERDdllaeaglddadaeAVEARREELEDRDeelrDRLEECR 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  786 TSAVDGAENAQRAmQETINKLnqkEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLE---NDIAEIMKSS 862
Cdd:PRK02224   335 VAAQAHNEEAESL-REDADDL---EERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfGDAPVDLGNA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  863 GDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQK--NVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQLTDMKKQ 939
Cdd:PRK02224   411 EDFLEELREERDELREREAELEATLRTARERVEEAEALLEagKCPECGQPVEGSPHvETIEEDRERVEELEAELEDLEEE 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  940 METSQNQYKdlQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslsSVLASARK 1019
Cdd:PRK02224   491 VEEVEERLE--RAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKR---EAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1020 EIELMSDKMRDLISEKETLAQERNTLKlEKESLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEaaEAKSR 1099
Cdd:PRK02224   566 EAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREAL----AELNDERRERLAEKR--ERKRE 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1100 QESTEKVALISEkskLLSEIETAQADLLKITQENDALRSSESTLLQQLKelqankdavdvACQKHIKEREELEHYQKLLE 1179
Cdd:PRK02224   639 LEAEFDEARIEE---AREDKERAEEYLEQVEEKLDELREERDDLQAEIG-----------AVENELEELEELRERREALE 704

                          570       580
                   ....*....|....*....|...
gi 2024359632 1180 ENDRVIKDKDDVIQRLQSSYDDL 1202
Cdd:PRK02224   705 NRVEALEALYDEAEELESMYGDL 727
COG5022 COG5022
Myosin heavy chain [General function prediction only];
640-1354 4.52e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 52.39  E-value: 4.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  640 EELKVSFNKGVGAQTAEFAELK-TQMEKVKLDYENEMSNLK-LKQENEKSQHLKEI-EALKAKLLEVT-EEKEQTLENLK 715
Cdd:COG5022    845 EVLIQKFGRSLKAKKRFSLLKKeTIYLQSAQRVELAERQLQeLKIDVKSISSLKLVnLELESEIIELKkSLSSDLIENLE 924

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  716 AKLEsvedqHLVEMEDTLNKLQEAEIKVSNLTKelQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkekftsavdgaena 795
Cdd:COG5022    925 FKTE-----LIARLKKLLNNIDLEEGPSIEYVK--LPELNKLHEVESKLKETSEEYEDLLKK------------------ 979

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  796 qraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEakvkLENDIAeIMKSSGDSSAQLMKMNDE 875
Cdd:COG5022    980 ---STILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAE----LQSASK-IISSESTELSILKPLQKL 1051

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  876 LRLKERQLEQiqlelTKANEKAVQLQknveqtaqkaeqsqqetlkthqeelKKMQDQLTDMKKQMETSQNQYKDLQAKye 955
Cdd:COG5022   1052 KGLLLLENNQ-----LQARYKALKLR-------------------------RENSLLDDKQLYQLESTENLLKTINVK-- 1099

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  956 ketsemitkhdaDIKGFKQNLLDAEEAL---KAAQKKNDELetqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLI 1032
Cdd:COG5022   1100 ------------DLEVTNRNLVKPANVLqfiVAQMIKLNLL----QEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA 1163

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1033 SEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQdrEELWTKNEELNSENKKILKQkeaaeAKSRQESTEKVALISEK 1112
Cdd:COG5022   1164 NLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEV--NDLKNELIALFSKIFSGWPR-----GDKLKKLISEGWVPTEY 1236

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1113 SKLLSEIEtaQADLLKITQENdalRSSEStLLQQLKELQankdavDVACQKHIKEREELEHYQKLLEENDrvikdkddvi 1192
Cdd:COG5022   1237 STSLKGFN--NLNKKFDTPAS---MSNEK-LLSLLNSID------NLLSSYKLEEEVLPATINSLLQYIN---------- 1294

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1193 qrlQSSYDDLARNQRELLQEVSiLTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEML--LKSREELCVSLA 1270
Cdd:COG5022   1295 ---VGLFNALRTKASSLRWKSA-TEVNYNSEELDDWCREFEISDVDEELEELIQAVKVLQLLKDDLnkLDELLDACYSLN 1370

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1271 NTanENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnFLEEMKSSREASNSEKIHLLQEALFASEQRLLAE 1350
Cdd:COG5022   1371 PA--EIQNLKSRYDPADKENNLPKEILKKIEALLIKQELQLSLEG-KDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSS 1447


                   ....
gi 2024359632 1351 REEL 1354
Cdd:COG5022   1448 LSAL 1451
PRK12704 PRK12704
phosphodiesterase; Provisional
 697-860 4.64e-06

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 51.70  E-value: 4.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  697 KAKLLEVTEEKEQTLENLKAKLESVEDQHLVEM-EDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNlsavnqvkdsLE 775
Cdd:PRK12704    30 EAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAkEEIHKLRNEFEKELRERRNELQKLEKRLLQKEEN----------LD 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  776 KELQLLKEKftsavdgaenaQRAMQETINKLNQKEEQFALMSSELEQLKSN-LTVME--TKLKEREEREQQLTEAKVKLE 852
Cdd:PRK12704   100 RKLELLEKR-----------EEELEKKEKELEQKQQELEKKEEELEELIEEqLQELEriSGLTAEEAKEILLEKVEEEAR 168


                   ....*...
gi 2024359632  853 NDIAEIMK 860
Cdd:PRK12704   169 HEAAVLIK 176
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1003-1226 8.62e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1003 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNS 1082
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1083 ---ENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEN-DALRSSESTLLQQLKELQANKDAVD 1158
Cdd:COG4942     98 eleAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632 1159 VACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEK 1226
Cdd:COG4942    178 ALLAELEEERAALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 771-1017 9.22e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 50.21  E-value: 9.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  771 KDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER-EQQLTEAKV 849
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  850 K-LENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKK 928
Cdd:COG3883     98 SgGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKAE-LEAAKAELEA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  929 MQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK 1008
Cdd:COG3883    176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAA 255


                   ....*....
gi 2024359632 1009 SLSSVLASA 1017
Cdd:COG3883    256 GAAAGSAGA 264
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 907-1152 1.01e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 50.21  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  907 TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAA 986
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE--------LEALQAEIDKLQAEIAEAEAEIEER 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  987 QkknDELETQAEELKKQAEQAKSLSSVLASA--------RKEIELMSDKMRDLISEketLAQERNTLKLEKESLlsqhle 1058
Cdd:COG3883     85 R---EELGERARALYRSGGSVSYLDVLLGSEsfsdfldrLSALSKIADADADLLEE---LKADKAELEAKKAEL------ 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1059 meskillvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1138
Cdd:COG3883    153 --------EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224

                          250
                   ....*....|....
gi 2024359632 1139 SESTLLQQLKELQA 1152
Cdd:COG3883    225 AAAAAAAAAAAAAA 238
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
604-848 1.03e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  604 ESLKTKLDHANKENSDVIEL---WKSKLESA--IASHQQAMEELKVSFNKGVGAQTAEFaeLKTQMEKVK---LDYENEM 675
Cdd:COG3206    121 ERLRKNLTVEPVKGSNVIEIsytSPDPELAAavANALAEAYLEQNLELRREEARKALEF--LEEQLPELRkelEEAEAAL 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  676 SNLKLKQ-----ENEKSQHLKEIEALKAKLLEVTEEkeqtLENLKAKLESVEDQhLVEMEDTLNKLQEAEIkVSNLTKEL 750
Cdd:COG3206    199 EEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAE----LAEAEARLAALRAQ-LGSGPDALPELLQSPV-IQQLRAQL 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  751 QGKEQKLLDLEKNLSA-----------VNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE 819
Cdd:COG3206    273 AELEAELAELSARYTPnhpdvialraqIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                          250       260
                   ....*....|....*....|....*....
gi 2024359632  820 LEQLKSNLTVMETKLKEREEREQQLTEAK 848
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAE 381
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
357-531 1.14e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 50.63  E-value: 1.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  357 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAAD 422
Cdd:COG2433    347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  423 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdlERKRQISEDPEntQTKLEhARIKELEQSLLFEKTKADKLQRELEDT 502
Cdd:COG2433    427 AEVEELEAELEEKDERIERLERELSEARS-----EERREIRKDRE--ISRLD-REIERLERELEEERERIEELKRKLERL 498

                          170       180       190
                   ....*....|....*....|....*....|
gi 2024359632  503 RvatvseksRIMELE-RDLALRVKEVAELR 531
Cdd:COG2433    499 K--------ELWKLEhSGELVPVKVVEKFT 520
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
652-1225 1.19e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  652 AQTAEFAELKTQMEKvkLDYENEMSNLKLKQE--NEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLvem 729
Cdd:COG4913    259 ELAERYAAARERLAE--LEYLRAALRLWFAQRrlELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR--- 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  730 EDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQ----ETINK 805
Cdd:COG4913    334 GNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAA 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  806 LNQKEEQFALMSSELEQL---KSNLTVMETKLKEREEREQQLTEAKVKLendIAEIMKSSGDSS---------------- 866
Cdd:COG4913    414 LRDLRRELRELEAEIASLerrKSNIPARLLALRDALAEALGLDEAELPF---VGELIEVRPEEErwrgaiervlggfalt 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  867 --------AQLMKMNDELRLKERqleqIQLELTKANEKAVQLQKNVEQT-AQKAEqsqqetLKTH------QEELKKM-- 929
Cdd:COG4913    491 llvppehyAAALRWVNRLHLRGR----LVYERVRTGLPDPERPRLDPDSlAGKLD------FKPHpfrawlEAELGRRfd 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  930 ------QDQLTDMKKQMeTSQNQYKDLQAKYEKETSEMITKH-------DADIKGFKQNLLDAEEALKAAQKKNDELETQ 996
Cdd:COG4913    561 yvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRRIRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAE 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  997 AEELKKQAEQAKSLSSV------LASARKEIELMSDKMRDLISEKETLAQerntLKLEKESLLSQHLEMESKILLVQQDR 1070
Cdd:COG4913    640 LDALQERREALQRLAEYswdeidVASAEREIAELEAELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEI 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1071 EELWTKNEELNSENKKILKQKEAAEAKSRQESTekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL-KE 1149
Cdd:COG4913    716 GRLEKELEQAEEELDELQDRLEAAEDLARLELR---ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRA 792

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632 1150 LQANKDAVDVACQKHIKEREELEHYQKLLE--ENDRVIKDKDDVIQRLQSSyddlarNQRELLQEVSILTAERDSAQE 1225
Cdd:COG4913    793 MRAFNREWPAETADLDADLESLPEYLALLDrlEEDGLPEYEERFKELLNEN------SIEFVADLLSKLRRAIREIKE 864
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
356-805 1.20e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.54  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  356 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHvlEMEAKMDQLRAMVEAADREKVELLNQLEEE 435
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  436 KRKVEDLQFRVEEESITKGDLERKRQisEDPENTQTKLEHA--RIKELEQSLLFEKTKADKLQRELEDTRVAtvseksri 513
Cdd:COG4717    159 RELEEELEELEAELAELQEELEELLE--QLSLATEEELQDLaeELEELQQRLAELEEELEEAQEELEELEEE-------- 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  514 MELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLS 593
Cdd:COG4717    229 LEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  594 ASNERMGKENESLKTKLDHANKENSDVIELWKSKLESaIASHQQAMEELKVSFNKgvGAQTAEFAELKTQMEKVKLDYEN 673
Cdd:COG4717    309 ALPALEELEEEELEELLAALGLPPDLSPEELLELLDR-IEELQELLREAEELEEE--LQLEELEQEIAALLAEAGVEDEE 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  674 EMSNlKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKaklesvEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGK 753
Cdd:COG4717    386 ELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALD------EEELEEELEELEEELEELEEELEELREELAEL 458

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024359632  754 EQKLLDLEKN--LSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 805
Cdd:COG4717    459 EAELEQLEEDgeLAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1625-1974 1.35e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1625 TEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQH------KYEVTEKEKMELvqENESLHAEWKSLVIINEEI 1698
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeRYQALLKEKREY--EGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1699 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsegkHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA----- 1773
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEE------------IEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASlersi 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1774 EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKqnnlkneEELTKSKELLNLENKKVEELKKEFEAL 1853
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1854 KLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDE---ERASL 1930
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEEL---QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKqewKLEQL 460

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2024359632 1931 QKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 1974
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1617-2006 1.52e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.12  E-value: 1.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1617 EKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhSCVSVMLDELQHKYEVTEKEKMELVQ--ENESLHAEwkslvii 1694
Cdd:pfam17380  234 EKMERRKESFNLAEDVTTMTPEYTVRYNGQTMTEN--EFLNQLLHIVQHQKAVSERQQQEKFEkmEQERLRQE------- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1695 NEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELlleEMSNLALKLREIERLQAQTFMQKFEADKRAE 1774
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMEREREL---ERIRQEERKRELERIRQEEIAMEISRMRELE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1775 ----EVLQTMEKVTKEKDAIHQEKIetlasLENSRQTNEKLQneldMLKQNNLKNEEELTKSKELLNLEnkkvEELKKEF 1850
Cdd:pfam17380  382 rlqmERQQKNERVRQELEAARKVKI-----LEEERQRKIQQQ----KVEMEQIRAEQEEARQREVRRLE----EERAREM 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1851 EALKLAAAQKSQQLAAL-QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERAS 1929
Cdd:pfam17380  449 ERVRLEEQERQQQVERLrQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKA 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1930 L----QKSISDTSALITQKDEELEKLRNEITVLRGEnasaktlQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTS 2005
Cdd:pfam17380  529 IyeeeRRREAEEERRKQQEMEERRRIQEQMRKATEE-------RSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   .
gi 2024359632 2006 P 2006
Cdd:pfam17380  602 P 602
PLN02939 PLN02939
transferase, transferring glycosyl groups
 690-941 1.56e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 50.29  E-value: 1.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  690 LKEIEALKAKLleVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEaeikvsNLTKELQGKEQKLLDLEKNLSAVNQ 769
Cdd:PLN02939   162 LTEKEALQGKI--NILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRN------ELLIRGATEGLCVHSLSKELDVLKE 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  770 VKDSLEKELQLLKEKFTSavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKV 849
Cdd:PLN02939   234 ENMLLKDDIQFLKAELIE-----------VAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKV 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  850 KLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQiqlELTKAN------EKAVQLQKNVEQTAQKAEQSQQET---LK 920
Cdd:PLN02939   303 ENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEA---SLKEANvskfssYKVELLQQKLKLLEERLQASDHEIhsyIQ 379

                          250       260
                   ....*....|....*....|.
gi 2024359632  921 THQEELKKMQDQLTDMKKQME 941
Cdd:PLN02939   380 LYQESIKEFQDTLSKLKEESK 400
PRK01156 PRK01156
chromosome segregation protein; Provisional
 492-1073 2.27e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 49.90  E-value: 2.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  492 ADKLQRELEDTRvatvSEKSRIMELERDLALRVKEVAELrgrlesSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQ-- 568
Cdd:PRK01156   168 YDKLKDVIDMLR----AEISNIDYLEEKLKSSNLELENI------KKQIADDEKSHSiTLKEIERLSIEYNNAMDDYNnl 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  569 ----REMSSLKEKFESSEEALRKEIKTLSASNERMGK----ENESLKTKLDHANKENSDVIELWKSKleSAIASHQQAME 640
Cdd:PRK01156   238 ksalNELSSLEDMKNRYESEIKTAESDLSMELEKNNYykelEERHMKIINDPVYKNRNYINDYFKYK--NDIENKKQILS 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  641 ELKVSFNK--GVGAQTAEFAELKTQMEKVKLDYE---NEMSNLKLKQENEKSqHLKEIEALKAKLlevtEEKEQTLENLK 715
Cdd:PRK01156   316 NIDAEINKyhAIIKKLSVLQKDYNDYIKKKSRYDdlnNQILELEGYEMDYNS-YLKSIESLKKKI----EEYSKNIERMS 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  716 AKLESVedqhlvemedtlnkLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSL-------EKELQLLKEKFTSA 788
Cdd:PRK01156   391 AFISEI--------------LKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALrenldelSRNMEMLNGQSVCP 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  789 VDGAENAQRAMQETINKLNQKEEQfalMSSELEQLKSNLTVMETKLKEREEREQQLteAKVKLENDIAEIMKSSgDSSAQ 868
Cdd:PRK01156   457 VCGTTLGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKDIDEKIVDLKKRKEYL--ESEEINKSINEYNKIE-SARAD 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  869 LMK-MNDELRLKERQLEQIQL-ELTKANEKAVQLQKNVEQTAQKAEQS--QQETLKTHQEELKKmqdQLTDMKKQMETSQ 944
Cdd:PRK01156   531 LEDiKIKINELKDKHDKYEEIkNRYKSLKLEDLDSKRTSWLNALAVISliDIETNRSRSNEIKK---QLNDLESRLQEIE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  945 NQYKDLQAKYEKETSEMitKHDADIKGFKQNLLDAEEALKaaqkknDELETQAEELKKQAEQAKSLSSVLASARKEIELM 1024
Cdd:PRK01156   608 IGFPDDKSYIDKSIREI--ENEANNLNNKYNEIQENKILI------EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDI 679

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632 1025 SDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREEL 1073
Cdd:PRK01156   680 EDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESM 728
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1921-2051 2.41e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.47  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1921 KEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASaktlqsvvktLESDKLKLEEKVKNLEQKLK-AKSEQ 1999
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEE----------LEAELEEKDERIERLERELSeARSEE 457

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 2000 PltvtspsgdiaANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2051
Cdd:COG2433    458 R-----------REIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 808-1687 2.84e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.40  E-value: 2.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  808 QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKvkleNDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQ 887
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEK----NALQEQLQAETELCAEAEEMRARLAARKQELEEIL 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  888 LEltkanekavqLQKNVEQTAQKAEQSQQETlkthqeelKKMQDQLTDMKKQMETSQNQYKDLQakYEKETSEmitkhdA 967
Cdd:pfam01576   78 HE----------LESRLEEEEERSQQLQNEK--------KKMQQHIQDLEEQLDEEEAARQKLQ--LEKVTTE------A 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  968 DIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQA----EQAKSLSSVLASARKEIELMSDKMRDliSEKETLAQERN 1043
Cdd:pfam01576  132 KIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLaeeeEKAKSLSKLKNKHEAMISDLEERLKK--EEKGRQELEKA 209

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1044 TLKLEKES--LLSQHLEMESKI--LLVQQDREE-------------------LWTKNEELNSENKKILKQKEAAEAKSRQ 1100
Cdd:pfam01576  210 KRKLEGEStdLQEQIAELQAQIaeLRAQLAKKEeelqaalarleeetaqknnALKKIRELEAQISELQEDLESERAARNK 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1101 ESTEKVALISEKSKLLSEIETAQaDLLKITQENDALRSSESTLLQ------------------------------QLKEL 1150
Cdd:pfam01576  290 AEKQRRDLGEELEALKTELEDTL-DTTAAQQELRSKREQEVTELKkaleeetrsheaqlqemrqkhtqaleelteQLEQA 368

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1151 QANKDAVDVACQKHIKEREELEHYQKLLE----ENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEK 1226
Cdd:pfam01576  369 KRNKANLEKAKQALESENAELQAELRTLQqakqDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1227 DLDLKSTHIALKNEIDCLlqtNRSLQSEKEMLlksREELCVSLANTANENQaLKLRKDEMQTELETEREKLEKMTKDNMD 1306
Cdd:pfam01576  449 LNEAEGKNIKLSKDVSSL---ESQLQDTQELL---QEETRQKLNLSTRLRQ-LEDERNSLQEQLEEEEEAKRNVERQLST 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1307 LKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQrlLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINEL 1386
Cdd:pfam01576  522 LQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQ--LEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNL 599

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1387 NlEKESVFSKSLQFEK-----------HNEALLREKD----ELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQ 1451
Cdd:pfam01576  600 E-KKQKKFDQMLAEEKaisaryaeerdRAEAEAREKEtralSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGK 678

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1452 ENTTLKYSIEALEEELkkknlenQELIACRSDLSDLLKEAQDARRTLENELAAV---------------SHAKQVLSSSF 1516
Cdd:pfam01576  679 NVHELERSKRALEQQV-------EEMKTQLEELEDELQATEDAKLRLEVNMQALkaqferdlqardeqgEEKRRQLVKQV 751

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1517 NTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARildkESFLLERMELQNNIGFLEKEVEEMREKNKEFL-- 1594
Cdd:pfam01576  752 RELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGR----EEAVKQLKKLQAQMKDLQRELEEARASRDEILaq 827

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1595 ---TEKELLVQEKE--KSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEV 1669
Cdd:pfam01576  828 skeSEKKLKNLEAEllQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTEL 907

                          970
                   ....*....|....*...
gi 2024359632 1670 TEKEKMELVQENESLHAE 1687
Cdd:pfam01576  908 LNDRLRKSTLQVEQLTTE 925
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1485-1999 3.48e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 3.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1485 SDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKEN---LTVEKKARILD 1561
Cdd:pfam05483  281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAhsfVVTEFEATTCS 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1562 KESFL-LERMELQNNIGFLEKEVEEMREKNKEfLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1640
Cdd:pfam05483  361 LEELLrTEQQRLEKNEDQLKIITMELQKKSSE-LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1641 SLS----VSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQE---NESLHAEWKSLVIINEEILKEKEKLSKEYYKLH 1713
Cdd:pfam05483  440 ELIfllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEklkNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1714 EKVVALLEQTDAdfscrllvsegkhellleemsnlalKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDaihqe 1793
Cdd:pfam05483  520 EDIINCKKQEER-------------------------MLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLD----- 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1794 KIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnlENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1873
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN---------KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNK 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1874 LAEELGRSRDE----VTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEErasLQKSISDTSALITQKDEELE 1949
Cdd:pfam05483  641 LELELASAKQKfeeiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKR---CQHKIAEMVALMEKHKHQYD 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1950 KLRNEITVLRGENASAKTLQSVVK-TLESDKLKLEEKVKNLEQKLKAKSEQ 1999
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKaALEIELSNIKAELLSLKKQLEIEKEE 768
46 PHA02562
endonuclease subunit; Provisional
 802-1001 3.97e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 48.86  E-value: 3.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  802 TINKLNQK-EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKE 880
Cdd:PHA02562   189 KIDHIQQQiKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  881 RQLEQIQLE-----------------------LTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQDQLTD 935
Cdd:PHA02562   269 SKIEQFQKVikmyekggvcptctqqisegpdrITKIKDKLKELQHSLEKldTAIDELEEIMDEFNEQSKKLLELKNKIST 348

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632  936 MKKQMETSQNQYKDLQAKYEKETSEMITkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1001
Cdd:PHA02562   349 NKQSLITLVDKAKKVKAAIEELQAEFVD-NAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLK 413
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 828-1416 4.28e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.07  E-value: 4.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  828 TVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ----IQLELTKANEKAVQLQKN 903
Cdd:pfam12128  244 TKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEkrdeLNGELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  904 VEQTAQKAEQSQQ---ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDA- 979
Cdd:pfam12128  324 LEALEDQHGAFLDadiETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIr 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  980 EEALKAAQKKNDELETQAEELKKQAEQAKSLSSV----LASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1055
Cdd:pfam12128  404 EARDRQLAVAEDDLQALESELREQLEAGKLEFNEeeyrLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1056 HLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS-----------EKSKLLSEIETAQA 1124
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHflrkeapdweqSIGKVISPELLHRT 563

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1125 DLlkITQENDALRSSESTLL------------------QQLK-ELQANKDAVDVACQKHIKEREELEHYQKLLEENDRvi 1185
Cdd:pfam12128  564 DL--DPEVWDGSVGGELNLYgvkldlkridvpewaaseEELReRLDKAEEALQSAREKQAAAEEQLVQANGELEKASR-- 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1186 kDKDDVIQRLQSSYDDLAR----NQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEM---- 1257
Cdd:pfam12128  640 -EETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTekqa 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1258 -LLKSREELCVSLA----NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEK 1332
Cdd:pfam12128  719 yWQVVEGALDAQLAllkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYF 798

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1333 IhLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafteKINELNLEKESVFSKSLQFEKhNEALLREKD 1412
Cdd:pfam12128  799 D-WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADT---------KLRRAKLEMERKASEKQQVRL-SENLRGLRC 867


                   ....
gi 2024359632 1413 ELER 1416
Cdd:pfam12128  868 EMSK 871
PRK01156 PRK01156
chromosome segregation protein; Provisional
 991-1563 4.65e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 4.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  991 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1070
Cdd:PRK01156   176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYE 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1071 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVA---LISEKSKLLSEIEtaqaDLLKITQENDALRSSESTLLQQL 1147
Cdd:PRK01156   256 SEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKnrnYINDYFKYKNDIE----NKKQILSNIDAEINKYHAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1148 KELQANKDAVdvacQKHIKEREELEH-----------YQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL 1216
Cdd:PRK01156   332 SVLQKDYNDY----IKKKSRYDDLNNqilelegyemdYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1217 TAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLlkSREELCVSLANTANENQALKLRKD--EMQTELETER 1294
Cdd:PRK01156   408 KKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEML--NGQSVCPVCGTTLGEEKSNHIINHynEKKSRLEEKI 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1295 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAL--FASEQRLLAER----EELVNENKAVTEKLTKA 1368
Cdd:PRK01156   486 REIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLedIKIKINELKDKhdkyEEIKNRYKSLKLEDLDS 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1369 TADAVLAETAFTEKINELNLEKesvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELdFSAKRL 1448
Cdd:PRK01156   566 KRTSWLNALAVISLIDIETNRS--------RSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANN-LNNKYN 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1449 LVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILN- 1527
Cdd:PRK01156   637 EIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSd 716

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2024359632 1528 -----RERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1563
Cdd:PRK01156   717 rindiNETLESMKKIKKAIGDLKRLREAFDKSGVPAMIRKS 757
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
597-1022 5.18e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 5.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  597 ERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQ--AMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENE 674
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEyaELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  675 MSNLKLKQENEK-----------SQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKV 743
Cdd:COG4717    129 PLYQELEALEAElaelperleelEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRL 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  744 SNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQL 823
Cdd:COG4717    209 AELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAL 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  824 KSNLTVMETKLKEREEREQQLTEAKVKLEN-DIAEIMKSSG--------------DSSAQLMKMNDELRLKERQLEQIQL 888
Cdd:COG4717    289 LFLLLAREKASLGKEAEELQALPALEELEEeELEELLAALGlppdlspeellellDRIEELQELLREAEELEEELQLEEL 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  889 ELTKANEKAVQLQKNVEQTAQKAEQSQQetLKTHQEELKKMQDQLTDMKKQMET--SQNQYKDLQAKYE------KETSE 960
Cdd:COG4717    369 EQEIAALLAEAGVEDEEELRAALEQAEE--YQELKEELEELEEQLEELLGELEEllEALDEEELEEELEeleeelEELEE 446

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  961 MITKHDADIKGFKQNLLDAEEALKAAQKKnDELETQAEELKKQAEQAKSL---SSVLASARKEIE 1022
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGELAELL-QELEELKAELRELAEEWAALklaLELLEEAREEYR 510
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 353-917 6.00e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 48.28  E-value: 6.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  353 ALQEALKeKQQHIEQLL-AERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADREKVELLNQ 431
Cdd:pfam10174   78 ALQDELR-AQRDLNQLLqQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQTLGAR 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  432 LEEEKRKVEDLQFRVEEESITKGDLERKRQISEdpentqtklEHARIKELEqSLLFEKTKADKLQRELEDTRVATVSEKS 511
Cdd:pfam10174  157 DESIKKLLEMLQSKGLPKKSGEEDWERTRRIAE---------AEMQLGHLE-VLLDQKEKENIHLREELHRRNQLQPDPA 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  512 RIMELERDLALRVKEVAELRgrlessKHIDDVDtslsllQEISSLQEKMAAAGKEHQREMSSLkEKFESSEEALRKEIKT 591
Cdd:pfam10174  227 KTKALQTVIEMKDTKISSLE------RNIRDLE------DEVQMLKTNGLLHTEDREEEIKQM-EVYKSHSKFMKNKIDQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  592 LSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQA-------------MEELKVSFNKGV-------- 650
Cdd:pfam10174  294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAailqtevdalrlrLEEKESFLNKKTkqlqdlte 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  651 --GAQTAEFAELKTQME---------KVKLDYENEMSNLKLKQENEKSQHLKEIE--------ALkAKLLEVTEEKEQTL 711
Cdd:pfam10174  374 ekSTLAGEIRDLKDMLDvkerkinvlQKKIENLQEQLRDKDKQLAGLKERVKSLQtdssntdtAL-TTLEEALSEKERII 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  712 ENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQ---VKDSLEKELQLLKEKFTSA 788
Cdd:pfam10174  453 ERLKEQREREDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASsglKKDSKLKSLEIAVEQKKEE 532

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  789 VDGAEN----------AQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEI 858
Cdd:pfam10174  533 CSKLENqlkkahnaeeAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQ 612

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632  859 MKSSGDSSAQLMKMNDELRLKERQLEQIQLElTKANEKAVQLQKNVEQTAQKAEQSQQE 917
Cdd:pfam10174  613 MKEQNKKVANIKHGQQEMKKKGAQLLEEARR-REDNLADNSQQLQLEELMGALEKTRQE 670
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 352-1041 6.50e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.50e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  352 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdGHDRHVLEMEAKMDQLRAMVEaadREKVELLNQ 431
Cdd:pfam01576  260 NNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALK-TELEDTLDTTAAQQELRSKRE---QEVTELKKA 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  432 LEEEKRK---------------VEDLQFRVEEESITKGDLERKRQISEdpenTQTKLEHARIKELEQSLLFEKTKADKLQ 496
Cdd:pfam01576  336 LEEETRSheaqlqemrqkhtqaLEELTEQLEQAKRNKANLEKAKQALE----SENAELQAELRTLQQAKQDSEHKRKKLE 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  497 RELEDTrvatvseKSRIMELERDLALRVKEVAELRGRLESskhiddvdtslsllqeISSLQEKMAAAGKEHQREMSSLKE 576
Cdd:pfam01576  412 GQLQEL-------QARLSESERQRAELAEKLSKLQSELES----------------VSSLLNEAEGKNIKLSKDVSSLES 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  577 KFESSEEALRKEIK---TLSASNERMGKENESLKTKLDHAnkensdviELWKSKLESAIASHQQAMEELKvsfnkgvgAQ 653
Cdd:pfam01576  469 QLQDTQELLQEETRqklNLSTRLRQLEDERNSLQEQLEEE--------EEAKRNVERQLSTLQAQLSDMK--------KK 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  654 TAEFAELKTQMEKVKLDYENEMSNLKLkQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVE------DQHLV 727
Cdd:pfam01576  533 LEEDAGTLEALEEGKKRLQRELEALTQ-QLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEkkqkkfDQMLA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  728 EMEDTLNKLQEAEIKVSNLTKElqgKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN 807
Cdd:pfam01576  612 EEKAISARYAEERDRAEAEARE---KETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKR 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  808 QKEEQFALMSSELEQLKSNLTVMEtklKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLkERQLEQIQ 887
Cdd:pfam01576  689 ALEQQVEEMKTQLEELEDELQATE---DAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEA-ELEDERKQ 764

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  888 LELTKANEKAVQLQ-KNVEQTAQKAEQSQQETLKthqeELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHD 966
Cdd:pfam01576  765 RAQAVAAKKKLELDlKELEAQIDAANKGREEAVK----QLKKLQAQMKDLQRELEEARASRDEILAQ-SKESEKKLKNLE 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  967 ADIKGFKQNLLDAEEALKAAQKKNDELE-----------TQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEK 1035
Cdd:pfam01576  840 AELLQLQEDLAASERARRQAQQERDELAdeiasgasgksALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQV 919


                   ....*.
gi 2024359632 1036 ETLAQE 1041
Cdd:pfam01576  920 EQLTTE 925
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 565-721 7.08e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 48.10  E-value: 7.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  565 KEHQREMSSLKEKFE---SSEEALRKEIKTLSASNERM---GKENESLKTKLDHANKENSDVIELWK------SKLESAI 632
Cdd:pfam05667  331 QQREEELEELQEQLEdleSSIQELEKEIKKLESSIKQVeeeLEELKEQNEELEKQYKVKKKTLDLLPdaeeniAKLQALV 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  633 ASHQQAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyenemsnlKLKQENEKSQHLKEIEALKAKLLEVTEE---KEQ 709
Cdd:pfam05667  411 DASAQRLVELAGQWEKHRVPLIEEYRALKEA---------------KSNKEDESQRKLEEIKELREKIKEVAEEakqKEE 475

                          170
                   ....*....|..
gi 2024359632  710 TLENLKAKLESV 721
Cdd:pfam05667  476 LYKQLVAEYERL 487
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 831-1022 7.10e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 7.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  831 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK 910
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  911 AEQSQQ--------------ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfKQNL 976
Cdd:COG3883     95 LYRSGGsvsyldvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL-----------EALK 163

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359632  977 LDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIE 1022
Cdd:COG3883    164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1768-1966 7.38e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1768 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1847
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1848 KEFEALkLAAAQKSQQ----------------------LAALQEENVKLAEELGRSRDEVTS-HQKLEEERSVLNNQLLE 1904
Cdd:COG4942    104 EELAEL-LRALYRLGRqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAAlRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 1905 MKKSLpsntLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAK 1966
Cdd:COG4942    183 LEEER----AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 404-1034 7.98e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.91  E-value: 7.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  404 VLEMEAKMDQLRAMVEA--ADREKVELLNQLEEEK--RKVEDLQFRVeeesitkgDLERKRQISEDPENTQTKLEHArik 479
Cdd:pfam12128  188 MHSKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQveHWIRDIQAIA--------GIMKIRPEFTKLQQEFNTLESA--- 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  480 ELEQSLLFEKTKADKLQRELEDTRVATVSE--KSRIMELERDLAlrvKEVAELRGRLESSKhiDDVDTSLSLLQEISSLQ 557
Cdd:pfam12128  257 ELRLSHLHFGYKSDETLIASRQEERQETSAelNQLLRTLDDQWK---EKRDELNGELSAAD--AAVAKDRSELEALEDQH 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  558 EKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAI----A 633
Cdd:pfam12128  332 GAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARdrqlA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  634 SHQQAMEELKVSFNKGVGAQTAEFAELKTQME------KVKLDYENEMSNLKLKQEN----------EKSQHLKEIEALK 697
Cdd:pfam12128  412 VAEDDLQALESELREQLEAGKLEFNEEEYRLKsrlgelKLRLNQATATPELLLQLENfderierareEQEAANAEVERLQ 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  698 AKLLEVTEEKEQTLENLKaklesVEDQHLVEMEDTLNKLQEAEIKVSN-----LTKELQGKEQKL-------------LD 759
Cdd:pfam12128  492 SELRQARKRRDQASEALR-----QASRRLEERQSALDELELQLFPQAGtllhfLRKEAPDWEQSIgkvispellhrtdLD 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  760 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAEN-------AQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMET 832
Cdd:pfam12128  567 PEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEElrerldkAEEALQSAREKQAAAEEQLVQANGELEKASREETFART 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  833 KLKEREEREQQLT----EAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQ-LEQIQLELTKANEKAVQLQKNVEQT 907
Cdd:pfam12128  647 ALKNARLDLRRLFdekqSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGA 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  908 AQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHdADIKGFKQNLLDAEEALKAA- 986
Cdd:pfam12128  727 LDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKI-ERIAVRRQEVLRYFDWYQETw 805

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632  987 QKKNDELETQAEELKKQAEQAK-SLSSVLASARKEI-ELM-----SDKMRDLISE 1034
Cdd:pfam12128  806 LQRRPRLATQLSNIERAISELQqQLARLIADTKLRRaKLEmerkaSEKQQVRLSE 860
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 978-1338 8.23e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 8.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  978 DAEEALKAAQKKNDELETQAEELKKQAEQAKSlssVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1057
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKE---ELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIR 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1058 EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1137
Cdd:pfam07888  133 ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQ 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1138 SSESTLLQQLKELQANKDAVDVACqkhikerEELEHYQKLLEENDRVIKDKDDVIQRLQSSYDdlaRNQRELLQevsilt 1217
Cdd:pfam07888  213 DTITTLTQKLTTAHRKEAENEALL-------EELRSLQERLNASERKVEGLGEELSSMAAQRD---RTQAELHQ------ 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1218 aERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS----EKEMLLKSREELcvslantanenqalkLRKDEMQTELETE 1293
Cdd:pfam07888  277 -ARLQAAQLTLQLADASLALREGRARWAQERETLQQsaeaDKDRIEKLSAEL---------------QRLEERLQEERME 340

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359632 1294 REKLE-KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE 1338
Cdd:pfam07888  341 REKLEvELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 822-1492 9.46e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.79  E-value: 9.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  822 QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAE---IMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 898
Cdd:pfam05483  107 KLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEnkdLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  899 QLQKNVEQTAQKAEQSQQETLKTHQEelkkMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLD 978
Cdd:pfam05483  187 DLNNNIEKMILAFEELRVQAENARLE----MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  979 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLE 1058
Cdd:pfam05483  263 LEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1059 MESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1138
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1139 SESTLLQQLKELQANKDAVDVACQKHIKEREELE-----------HYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQR 1207
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiktseeHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1208 ELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE----KEMLLKSREELCVSLANTANENQALKLRK 1283
Cdd:pfam05483  503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1284 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSE------KIHLLQEALFASEQRLlaerEELVNE 1357
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeiKVNKLELELASAKQKF----EEIIDN 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1358 NKAVTEkLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDelERKYSELLDEKKSLENAFSDMKR 1437
Cdd:pfam05483  659 YQKEIE-DKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKH--KHQYDKIIEERDSELGLYKNKEQ 735

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632 1438 EQEldfSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQ 1492
Cdd:pfam05483  736 EQS---SAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 429-1095 1.07e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  429 LNQLEEEKRKVEDLQFRVEEEsitkgdLERKRQISEDPENTQTKLEHaRIKELEQSLLFEKTKADKLQRELEDTRVATVS 508
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTE------IKKKEKELEKLNNKYNDLKK-QKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  509 EKSRIMELE------RDLALRVKEVAELRGRLESSKHIDDVDTSlSLLQEISSLQEKMAAAGKEHQREMSSLKEKfesse 582
Cdd:TIGR04523  199 LELLLSNLKkkiqknKSLESQISELKKQNNQLKDNIEKKQQEIN-EKTTEISNTQTQLNQLKDEQNKIKKQLSEK----- 272

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  583 ealRKEIKTLSASNERMGKENESLKTKLDHANKENSdviELWKSKLESAIASHQQAMEELKVSFNKgvgaQTAEFAELKT 662
Cdd:TIGR04523  273 ---QKELEQNNKKIKELEKQLNQLKSEISDLNNQKE---QDWNKELKSELKNQEKKLEEIQNQISQ----NNKIISQLNE 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  663 QMEKVKLDYENEMSNlklkqENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEdqhlvemedtlNKLQEAEIK 742
Cdd:TIGR04523  343 QISQLKKELTNSESE-----NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE-----------SKIQNQEKL 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  743 VSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 822
Cdd:TIGR04523  407 NQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  823 LKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQK 902
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEK 566

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  903 NVEqtaqkaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfkqnlldaEEA 982
Cdd:TIGR04523  567 NKE----------IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL------------------EKE 618

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  983 LKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESK 1062
Cdd:TIGR04523  619 LEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYIT 698

                          650       660       670
                   ....*....|....*....|....*....|...
gi 2024359632 1063 ILLVQQDREELWTKNEELNSENKKILKQKEAAE 1095
Cdd:TIGR04523  699 RMIRIKDLPKLEEKYKEIEKELKKLDEFSKELE 731
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 925-1160 1.12e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  925 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadikgfkqnLLDAEEALKAAQKKNDELETQAEELKKQA 1004
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE---------------YNELQAELEALQAEIDKLQAEIAEAEAEI 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1005 EQAKS-LSSVLASARK--------EIELMSDKMRDLISEKETLAQerntlklekesllsqhlemeskilLVQQDREELwt 1075
Cdd:COG3883     82 EERREeLGERARALYRsggsvsylDVLLGSESFSDFLDRLSALSK------------------------IADADADLL-- 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1076 knEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKD 1155
Cdd:COG3883    136 --EELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213


                   ....*
gi 2024359632 1156 AVDVA 1160
Cdd:COG3883    214 AAAAA 218
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 789-1152 1.14e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  789 VDGAENAQRAMQETINKLNQKEEQFALMSSELEQLksnltvmetklkerEEREQQLTEakvklENDIAeimkssgdsSAQ 868
Cdd:COG3096    284 SERALELRRELFGARRQLAEEQYRLVEMARELEEL--------------SARESDLEQ-----DYQAA---------SDH 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  869 LMKMNDELRLKERqLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQN--- 945
Cdd:COG3096    336 LNLVQTALRQQEK-IERYQEDLEELTERLEEQEEVVEE-AAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTrai 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  946 QYKD-LQAKYEKE--------TSEMITKHDADIK-----------GFKQNLLDA-------EEALKAAQKKNDELET--- 995
Cdd:COG3096    414 QYQQaVQALEKARalcglpdlTPENAEDYLAAFRakeqqateevlELEQKLSVAdaarrqfEKAYELVCKIAGEVERsqa 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  996 ---------QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL----------ISEKETLAQERNTLKLEKESLLSQH 1056
Cdd:COG3096    494 wqtarellrRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeefcqrigqqLDAAEELEELLAELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1057 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEaKSRQESTEKVAlisEKSKLLSEIETAQADLLKITQENDAL 1136
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALE-RLREQSGEALA---DSQEVTAAMQQLLEREREATVERDEL 649

                          410
                   ....*....|....*.
gi 2024359632 1137 RSSESTLLQQLKELQA 1152
Cdd:COG3096    650 AARKQALESQIERLSQ 665
mukB PRK04863
chromosome partition protein MukB;
622-1006 1.20e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  622 ELWKSKleSAIASHQQAMEELKvsfnkgvgaqtAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhlKEIEALKAKLL 701
Cdd:PRK04863   294 ELYTSR--RQLAAEQYRLVEMA-----------RELAELNEAESDLEQDYQAASDHLNLVQTALRQQ--EKIERYQADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  702 EVTEEkeqtlenLKAKLESVEDQHLvEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLL 781
Cdd:PRK04863   359 ELEER-------LEEQNEVVEEADE-QQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLC 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  782 kekftsavdgaenaqRAMQETINKLNQKEEQFAlmsSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKS 861
Cdd:PRK04863   431 ---------------GLPDLTADNAEDWLEEFQ---AKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRS 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  862 SGDSSAQ-LMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQ-----------------SQQETLKTHQ 923
Cdd:PRK04863   493 EAWDVAReLLRRLREQRHLAEQLQQLRMRLSEL-EQRLRQQQRAERLLAEFCKrlgknlddedeleqlqeELEARLESLS 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  924 EELKKMQDQLTDMKKQMETSQNQYKDL----------QAKYEK---------ETSEMITkhdadikGFKQNLLdaeEALK 984
Cdd:PRK04863   572 ESVSEARERRMALRQQLEQLQARIQRLaarapawlaaQDALARlreqsgeefEDSQDVT-------EYMQQLL---ERER 641

                          410       420
                   ....*....|....*....|..
gi 2024359632  985 AAQKKNDELETQAEELKKQAEQ 1006
Cdd:PRK04863   642 ELTVERDELAARKQALDEEIER 663
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1066-1496 1.24e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1066 VQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSES--TL 1143
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1144 LQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQ-RELLQEVSILTAERDS 1222
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1223 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQ-----SEKEMLLKSREELCV--------------------------SLAN 1271
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLAllglggsllsliltiagvlflvlgllALLF 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1272 TANENQALKLRKDEMQTELETEREKLEK------MTKDNMDLKASLSSLSNFLEEMKSSREAsNSEKIHLLQEALfasEQ 1345
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEeeleelLAALGLPPDLSPEELLELLDRIEELQEL-LREAEELEEELQ---LE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1346 RLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQF-EKHNEALLREK--------DELER 1416
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELlEALDEEELEEEleeleeelEELEE 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1417 KYSELLDEKKSLENAFSDMKREQELDfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARR 1496
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGELA------------ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 791-1045 1.25e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 47.49  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  791 GAENAQRAMQETINKLNQ---KEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSA 867
Cdd:PRK10246   333 HAAKQSAELQAQQQSLNTwlaEHDRFRQWNNELAGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVA 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  868 QLMkmndELRLKERQLEQiqlELTKANEKAVQLQKNVEQTaqkaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQY 947
Cdd:PRK10246   413 AAL----AQHAEQRPLRQ---RLVALHGQIVPQQKRLAQL--------QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQL 477

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  948 KDLQAKYEKEtsEMItkhdADIKGFKQNL----------------LDAEEALK--AAQKKNDELEtqaEELKKQAEQAKS 1009
Cdd:PRK10246   478 ADVKTICEQE--ARI----KDLEAQRAQLqagqpcplcgstshpaVEAYQALEpgVNQSRLDALE---KEVKKLGEEGAA 548

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 2024359632 1010 LSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1045
Cdd:PRK10246   549 LRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAV 584
WEMBL pfam05701
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ...
 568-928 1.38e-04

Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".


Pssm-ID: 461718 [Multi-domain]  Cd Length: 562  Bit Score: 46.95  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  568 QREMSSLKEKFESSEEALRKEIKTLsasnERMGKENESLKTKLDHANKE------NSDVIELWKSKLESAIASHQQ--AM 639
Cdd:pfam05701   48 QEEIPEYKKQSEAAEAAKAQVLEEL----ESTKRLIEELKLNLERAQTEeaqakqDSELAKLRVEEMEQGIADEASvaAK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  640 EELKVSFNKGVGAqTAEFAELKTQMEKVKLDYENemsnlkLKQENEKSQHLKEIEALKAKLLEVTEEkEQTLE--NLKAK 717
Cdd:pfam05701  124 AQLEVAKARHAAA-VAELKSVKEELESLRKEYAS------LVSERDIAIKRAEEAVSASKEIEKTVE-ELTIEliATKES 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  718 LESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKE---LQLLKEKFTSAVDGAEN 794
Cdd:pfam05701  196 LESAHAAHLEAEEHRIGAALAREQDKLNWEKELKQAEEELQRLNQQLLSAKDLKSKLETAsalLLDLKAELAAYMESKLK 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  795 aQRAMQETINKLNQKEEQFALMSS--ELEQLKSN----------LTVMETKLKEREEREQQlteakvklenDIAEIMKSS 862
Cdd:pfam05701  276 -EEADGEGNEKKTSTSIQAALASAkkELEEVKANiekakdevncLRVAAASLRSELEKEKA----------ELASLRQRE 344

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632  863 GDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKThQEELKK 928
Cdd:pfam05701  345 GMASIAVSSLEAELNRTKSEIALVQAKEKEAREKMVELPKQLQQAAQEAEEAKSLAQAA-REELRK 409
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 691-1018 1.42e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  691 KEIEALKAKLLEVTEE------KEQTLENLKAKLESVEDQHLV---------EMEDTLNKLQEAEIKVSNLTKELQGKEQ 755
Cdd:COG3096    785 KRLEELRAERDELAEQyakasfDVQKLQRLHQAFSQFVGGHLAvafapdpeaELAALRQRRSELERELAQHRAQEQQLRQ 864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  756 KLLDLEKNLSAVNQVKDSL----EKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKsNLTVME 831
Cdd:COG3096    865 QLDQLKEQLQLLNKLLPQAnllaDETLADRLEELREELDAAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADY 943

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  832 TKLKEREEREQQLTEAkvklendIAEIMK-----SSGDSSAQLMK---MNDELRlkeRQLEQIQLELTKANEKAVQLQKN 903
Cdd:COG3096    944 LQAKEQQRRLKQQIFA-------LSEVVQrrphfSYEDAVGLLGEnsdLNEKLR---ARLEQAEEARREAREQLRQAQAQ 1013

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  904 VEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQykdlQAKYEK-ETSEMITKHDADIKGFKQNLLDAEEA 982
Cdd:COG3096   1014 YSQ-YNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEE----RARIRRdELHEELSQNRSRRSQLEKQLTRCEAE 1088

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 2024359632  983 LKAAQKKNDELETQAEELKKQAEQAK-SLSSVLASAR 1018
Cdd:COG3096   1089 MDSLQKRLRKAERDYKQEREQVVQAKaGWCAVLRLAR 1125
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1405-1955 1.43e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 47.24  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1405 EALLREKDELERKYSELLDEKKSLENAFSDMKRE-QELDFSAKRLLVQENTTLKySIEALEEELKKKNLENQELIACRSD 1483
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLElEELELELEEAQAEEYELLA-ELARLEQDIARLEERRRELEERLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1484 LSDLLKEAQDARRTLENELAAVShakqvlsssfntcssdiEILNRERTELQDKCQKLTgEVENMKENLTVEKKARILDKE 1563
Cdd:COG1196    321 LEEELAELEEELEELEEELEELE-----------------EELEEAEEELEEAEAELA-EAEEALLEAEAELAEAEEELE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1564 SFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLS 1643
Cdd:COG1196    383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1644 VSKAELEDVHSCVSVMLDELQHKYEvtEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLH--EKVVALLE 1721
Cdd:COG1196    463 ELLAELLEEAALLEAALAELLEELA--EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgvEAAYEAAL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1722 QTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETL--A 1799
Cdd:COG1196    541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVlgD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1800 SLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELG 1879
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1880 RSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEI 1955
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1789-1999 1.49e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1789 AIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQ 1868
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1869 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQllemkksLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEEL 1948
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1949 EKLRNEITVLRGENASAKtlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQ 1999
Cdd:COG4942    170 EAERAELEALLAELEEER------AALEALKAERQKLLARLEKELAELAAE 214
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1460-1996 1.64e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 1.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1460 IEALEEELKKKNLE----NQELIACRSDLSDLLKEAQDarrtLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQD 1535
Cdd:PRK01156   185 IDYLEEKLKSSNLEleniKKQIADDEKSHSITLKEIER----LSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1536 KCQKLTGEVENMKENLTVEKkarildkesfllERMELQNNigflekEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVI 1615
Cdd:PRK01156   261 AESDLSMELEKNNYYKELEE------------RHMKIIND------PVYKNRNYINDYFKYKNDIENKKQILSNIDAEIN 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1616 KEKMILYK--ETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVI 1693
Cdd:PRK01156   323 KYHAIIKKlsVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1694 INEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHEL------------LLEEMSNLALKL--REIERLQ 1759
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttLGEEKSNHIINHynEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1760 AQTFMQKFEADKRAEEVLQtmekVTKEKDAIHQEKIETLAS----LENSRQTNEKLQNELDMLKQNNLKNEE--ELTKSK 1833
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVD----LKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEikNRYKSL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1834 ELLNLENKKVEELKK-------EFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1905
Cdd:PRK01156   559 KLEDLDSKRTSWLNAlavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKYNEI 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1906 K-KSLPSNTLREST--LKKEIdEERASLQKSISDTSALITQKDEELEKLRNEitvLRGENASAKTLQSVVKTLESDKLKL 1982
Cdd:PRK01156   639 QeNKILIEKLRGKIdnYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINEL 714

                          570
                   ....*....|....
gi 2024359632 1983 EEKVKNLEQKLKAK 1996
Cdd:PRK01156   715 SDRINDINETLESM 728
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1516-2049 1.72e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 1.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1516 FNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNnigfLEKEVEEMREKNKEFLT 1595
Cdd:TIGR04523   70 INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNK----LEKQKKENKKNIDKFLT 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1596 EKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScvsvMLDELQHKYEVTEKEKM 1675
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQIS 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1676 ELVQENESLHAEWKSLviiNEEILKEKEKLSKEYYKL------HEKVVALLEQTDADfscrLLVSEGKHELLLEEMSNLA 1749
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKK---QQEINEKTTEISNTQTQLnqlkdeQNKIKKQLSEKQKE----LEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1750 LKLREIERLQAQTFMQKF--EADKRAEEVLQTMEKVTKEKDAIHQ--EKIETL-ASLENSRQTNEKLQNELDMlKQNNLK 1824
Cdd:TIGR04523  295 SEISDLNNQKEQDWNKELksELKNQEKKLEEIQNQISQNNKIISQlnEQISQLkKELTNSESENSEKQRELEE-KQNEIE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1825 --NEEELTKSKELLNLENKKvEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK----LEEERSVL 1898
Cdd:TIGR04523  374 klKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeikdLTNQDSVK 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1899 NNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKsisdTSALITQKDEELEKLRNEITVLRGEnasaktlqsvVKTLESD 1978
Cdd:TIGR04523  453 ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKKLNEEKKELEEK----------VKDLTKK 518

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359632 1979 KLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQD---ESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQ 2049
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnleKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 683-1082 1.78e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.97  E-value: 1.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  683 ENEKSQHLKEIEALKakllevTEEKEQTLENLKAKLESVEdqhlvEMEDTLNKLQEAEIKVSN---LTKELQGKEQKLLD 759
Cdd:PRK10929    25 EKQITQELEQAKAAK------TPAQAEIVEALQSALNWLE-----ERKGSLERAKQYQQVIDNfpkLSAELRQQLNNERD 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  760 LEKNLSAvNQVKDSLEKEL-----QLLkekftsavdgaenaqramqETINKLNQKEEQFALMSSELEQLKsnltvmetkl 834
Cdd:PRK10929    94 EPRSVPP-NMSTDALEQEIlqvssQLL-------------------EKSRQAQQEQDRAREISDSLSQLP---------- 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  835 kereereQQLTEAKvKLENDIAEIMKSSGDSSAQLmkmndelrlkerqlEQIQLELTKANEKAVQLQKNVEQTAQKAEQS 914
Cdd:PRK10929   144 -------QQQTEAR-RQLNEIERRLQTLGTPNTPL--------------AQAQLTALQAESAALKALVDELELAQLSANN 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  915 QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDAD-----IKGFKQNlLDAEEALKAAQKK 989
Cdd:PRK10929   202 RQELARLRSELAKKRSQQLDAYLQALRNQLNSQRQREAERALESTELLAEQSGDlpksiVAQFKIN-RELSQALNQQAQR 280

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  990 NDELETQAEELKKQA-----------EQAKSL--SSVLASA-RKEIELMSD--KMRDLISEKETLAQERntLK----LEK 1049
Cdd:PRK10929   281 MDLIASQQRQAASQTlqvrqalntlrEQSQWLgvSNALGEAlRAQVARLPEmpKPQQLDTEMAQLRVQR--LRyedlLNK 358

                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 2024359632 1050 ESLLSQHLEMESKILLVQQDR---EELWTKNEELNS 1082
Cdd:PRK10929   359 QPQLRQIRQADGQPLTAEQNRildAQLRTQRELLNS 394
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1748-1954 1.89e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1748 LALKLREIERLQAQtfmqKFEADKRAEEVLQTMEKVTKEKDAIHQekietLASLENSRQTNEKLQNELdmlkqnnlkneE 1827
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREI-----------A 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1828 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEmkk 1907
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--- 748

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359632 1908 SLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNE 1954
Cdd:COG4913    749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1078-1354 1.93e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 1.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1078 EELNSENKKILKQKEAAEAKSRQESTEKVALI--SEKSKLLSEIETAQA--DLLKITQENDALRSSESTLLQQLKELQAN 1153
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIqnAEKNILLLNQARLQAleDLEKILTEKEALQGKINILEMRLSETDAR 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1154 kdaVDVACQKHIKEREELEHYQKLLEEndrvikdkddVIQRLQSSYddlarnqrellQEVSILTAERDSAQEKDLDLKST 1233
Cdd:PLN02939   186 ---IKLAAQEKIHVEILEEQLEKLRNE----------LLIRGATEG-----------LCVHSLSKELDVLKEENMLLKDD 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1234 HIALKNEIDCLLQTNRS---LQSEKEMLLKSREEL-CVSLANTANENQALKLRKDEMQTELETEREKLEKMTK------- 1302
Cdd:PLN02939   242 IQFLKAELIEVAETEERvfkLEKERSLLDASLRELeSKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNqvekaal 321

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632 1303 ---DNMDLKASLSSLSNFLEEMKSSREASnsEKIHLLQEALFASEQRLLAEREEL 1354
Cdd:PLN02939   322 vldQNQDLRDKVDKLEASLKEANVSKFSS--YKVELLQQKLKLLEERLQASDHEI 374
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1385-1816 2.71e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1385 ELNLEKESVFSKSLQFEK-HNEALLREKDE----LERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYS 1459
Cdd:pfam01576  109 EEQLDEEEAARQKLQLEKvTTEAKIKKLEEdillLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1460 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK 1539
Cdd:pfam01576  189 ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1540 LTGEVENMKENLTVEKKARILDK-------ESFLLERMELQNNIGFL----------EKEVEEMREKNKEFLTEKELLVQ 1602
Cdd:pfam01576  269 LEAQISELQEDLESERAARNKAEkqrrdlgEELEALKTELEDTLDTTaaqqelrskrEQEVTELKKALEEETRSHEAQLQ 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1603 EKEKSET--------KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1674
Cdd:pfam01576  349 EMRQKHTqaleelteQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1675 MELVQENESLHAEWKSLVIINEEILKEKEKLSKEY----YKLHEKVVALLEQTDA--DFSCRLLVSEGKHELLLEEMSNL 1748
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVssleSQLQDTQELLQEETRQklNLSTRLRQLEDERNSLQEQLEEE 508

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359632 1749 ALKLREIERLQAQTFMQKFEADKRAEEVLQTME-------KVTKEKDAIHQEKIETLASLENSRQTNEKLQNELD 1816
Cdd:pfam01576  509 EEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkkRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
337-595 3.06e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  337 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALVRDGHDRhVLEMEAKMDQLRA 416
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  417 MVEAADREKVELLNQLEEEKRKVEDLQfrveeesitkGDLERKRQISEDPENTQTKLEHARIKELEQSLLFEKtKADKLQ 496
Cdd:COG4913    700 ELEELEEELDELKGEIGRLEKELEQAE----------EELDELQDRLEAAEDLARLELRALLEERFAAALGDA-VERELR 768

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  497 RELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRlESSKHIDDVDTSLSLLQEISS-----LQEKMAAAGKEH-QRE 570
Cdd:COG4913    769 ENLEERIDALRARLNRAEEELERAMRAFNREWPAETA-DLDADLESLPEYLALLDRLEEdglpeYEERFKELLNENsIEF 847

                          250       260
                   ....*....|....*....|....*
gi 2024359632  571 MSSLKEKFESSEEALRKEIKTLSAS 595
Cdd:COG4913    848 VADLLSKLRRAIREIKERIDPLNDS 872
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
810-1034 3.09e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  810 EEQFALMSSELEQLKSnltvMETKLKEREEREQQLTEAKvklenDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQ 887
Cdd:COG4913    224 FEAADALVEHFDDLER----AHEALEDAREQIELLEPIR-----ELAERYAAARERLAELEYLRAALRLwfAQRRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  888 LELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQ---AKYEKETSEMITK 964
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERErrrARLEALLAALGLP 374

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632  965 HDADIKGFKQN-------LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISE 1034
Cdd:COG4913    375 LPASAEEFAALraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAE 451
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
479-916 3.17e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 3.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  479 KELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALR--VKEVAELRGRLESSkhIDDVDTSLSLLQEISSL 556
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLplYQELEALEAELAEL--PERLEELEERLEELREL 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  557 QEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVielwKSKLESAIASHQ 636
Cdd:COG4717    162 EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL----EEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  637 QAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENE----------MSNLKLKQENEKSQHLKEIEALKAkLLEVTEE 706
Cdd:COG4717    238 AAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlglLALLFLLLAREKASLGKEAEELQA-LPALEEL 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  707 KEQTLENLKAKL---ESVEDQHLVEMEDTLNKLQEAEIKVSNLTKELQgkEQKLLDLEKNLSAVNQVKDslEKELQLLKE 783
Cdd:COG4717    317 EEEELEELLAALglpPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVED--EEELRAALE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  784 KFTSAVDgAENAQRAMQETINKLNqKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMkssg 863
Cdd:COG4717    393 QAEEYQE-LKEELEELEEQLEELL-GELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLE---- 466

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024359632  864 dSSAQLMKMNDELRLKERQLEqiqlELTKANEKAVQLQKNVEQTAQKAEQSQQ 916
Cdd:COG4717    467 -EDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREERL 514
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1767-2002 3.97e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.66  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1767 FEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKEllnlENKKVEEL 1846
Cdd:PLN02939   124 QLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQ----EKIHVEIL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1847 KKEFEALKLAAAQK-----------SQQLAALQEENVKLAEELGRSRDEVTSHQ-------KLEEERSVLNNQLLEMKKS 1908
Cdd:PLN02939   200 EEQLEKLRNELLIRgateglcvhslSKELDVLKEENMLLKDDIQFLKAELIEVAeteervfKLEKERSLLDASLRELESK 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1909 L---PSNTLRESTLKKEIDEERA-SLQ------KSISDTSALITQKDEELEKLRNEItvlrgeNASAKtlQSVVKTLESD 1978
Cdd:PLN02939   280 FivaQEDVSKLSPLQYDCWWEKVeNLQdlldraTNQVEKAALVLDQNQDLRDKVDKL------EASLK--EANVSKFSSY 351

                          250       260
                   ....*....|....*....|....*
gi 2024359632 1979 KLKL-EEKVKNLEQKLKAKSEQPLT 2002
Cdd:PLN02939   352 KVELlQQKLKLLEERLQASDHEIHS 376
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1742-1960 3.97e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 3.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1742 LEEMSNLALKLRE-IERLQaqtfmqkfeadkRAEEVLQTMEKVTKEKDaiHQEKIETLASLENSRQTNEKLQNELDmlkq 1820
Cdd:COG4913    237 LERAHEALEDAREqIELLE------------PIRELAERYAAARERLA--ELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1821 nnlKNEEELTKSKELLNLENKKVEELKKEFEALKLA-AAQKSQQLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLN 1899
Cdd:COG4913    299 ---ELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERR---RARLEALLAALG 372

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1900 NQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRG 1960
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 622-1006 4.00e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.71  E-value: 4.00e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  622 ELWKSKleSAIASHQQAMEELkvsfnkgvgaqTAEFAELKTQMEKVKLDYENEMSNLKLKQE----NEKSQHLKE-IEAL 696
Cdd:COG3096    293 ELFGAR--RQLAEEQYRLVEM-----------ARELEELSARESDLEQDYQAASDHLNLVQTalrqQEKIERYQEdLEEL 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  697 KAKLLE---VTEEKEQTLENLKAKLESVED------------QHLVEMEDT--------LNKLQEAE--IKVSNLTKE-- 749
Cdd:COG3096    360 TERLEEqeeVVEEAAEQLAEAEARLEAAEEevdslksqladyQQALDVQQTraiqyqqaVQALEKARalCGLPDLTPEna 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  750 ------LQGKEQ----KLLDLEKNLSAVNQVKDSLEKELQLLkEKFTSAVDGAENAQRAmQETINKLnqkeeqfalmsSE 819
Cdd:COG3096    440 edylaaFRAKEQqateEVLELEQKLSVADAARRQFEKAYELV-CKIAGEVERSQAWQTA-RELLRRY-----------RS 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  820 LEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQ 899
Cdd:COG3096    507 QQALAQRLQQLRAQLAELEQRLRQQQNAERLLE----EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSE 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  900 LQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQLTDMKKQmetSQNQYKDLQakyeketsemitkhdaDIKGFKQNLLDA 979
Cdd:COG3096    583 LRQQLEQLRARIKE-----LAARAPAWLAAQDALERLREQ---SGEALADSQ----------------EVTAAMQQLLER 638

                          410       420
                   ....*....|....*....|....*..
gi 2024359632  980 EEALKAAQkknDELETQAEELKKQAEQ 1006
Cdd:COG3096    639 EREATVER---DELAARKQALESQIER 662
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
394-1022 4.01e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  394 ALVRDghdrHVLEMEAKMDQLRAMVEAADrEKVELLNQLEEEKRKVEDLQfrveeesitkgdlerkrQISEDPENTQTKL 473
Cdd:COG4913    211 DFVRE----YMLEEPDTFEAADALVEHFD-DLERAHEALEDAREQIELLE-----------------PIRELAERYAAAR 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  474 EHARIKELEQSLL---FEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRLESSkhidDVDTSLSLL 550
Cdd:COG4913    269 ERLAELEYLRAALrlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGN----GGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  551 QEISSLQEKMAAAGKEHQR---EMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKSK 627
Cdd:COG4913    345 REIERLERELEERERRRARleaLLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE-LRE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  628 LESAIASHQQ-------AMEELKVSFNKGVGAQTAE---FAEL----------KTQMEK----------VKLDYENEMS- 676
Cdd:COG4913    424 LEAEIASLERrksnipaRLLALRDALAEALGLDEAElpfVGELievrpeeerwRGAIERvlggfaltllVPPEHYAAALr 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  677 ---NLKLKQE------NEKSQHLKEIEALKAKLLEVTEEKEQTLEN-LKAKLESVEDQHLVEMEDTLNKL---------- 736
Cdd:COG4913    504 wvnRLHLRGRlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDYVCVDSPEELRRHpraitragqv 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  737 ----------------------QEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLkekftSAVDGAEN 794
Cdd:COG4913    584 kgngtrhekddrrrirsryvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSW 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  795 AQRAMQETINKLNQKEEQFAlmssELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmnd 874
Cdd:COG4913    659 DEIDVASAEREIAELEAELE----RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRL---------------- 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  875 elrlkERQLEQIQLELTkanekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKmQDQLTDMKKQMETSQNQYKDLQAKY 954
Cdd:COG4913    719 -----EKELEQAEEELD-------ELQDRLEAAEDLARLELRALLEERFAAALG-DAVERELRENLEERIDALRARLNRA 785

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632  955 EKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQ---------AEELKKQAEQAKS-LSSVLASARKEIE 1022
Cdd:COG4913    786 EEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDglpeyeerfKELLNENSIEFVAdLLSKLRRAIREIK 863
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
917-1161 4.51e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  917 ETLKTHQEELKKMQDQLTDMKKQMETSQnQYKDLQAKYEKETSEmITKHDADIKGfkqnlLDAEEALKAAQKKNDELETQ 996
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLE-PIRELAERYAAARER-LAELEYLRAA-----LRLWFAQRRLELLEAELEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  997 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL-ISEKETLAQERNTLKLEKESLLSQHLEMESKI----LLVQQDRE 1071
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLaalgLPLPASAE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1072 ELWtkneelnsenkkilKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTL---LQQLK 1148
Cdd:COG4913    381 EFA--------------ALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIparLLALR 446

                          250
                   ....*....|....*...
gi 2024359632 1149 -----ELQANKDAVDVAC 1161
Cdd:COG4913    447 dalaeALGLDEAELPFVG 464
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 376-928 4.62e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.50  E-value: 4.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  376 RAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEaadrEKVELLNQLEEEKRKVEDLQFRVEEESITKGD 455
Cdd:pfam05557    1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASALKRQLD----RESDRNQELQKRIRLLEKREAEAEEALREQAE 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  456 LERKRQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRV---ATVSEKSRIMELERDLALRVKEVAELRG 532
Cdd:pfam05557   77 LNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELelqSTNSELEELQERLDLLKAKASEAEQLRQ 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  533 RLESSKH-IDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEkFESSEEALRKEIKTLSASNERMG---KENESLKT 608
Cdd:pfam05557  157 NLEKQQSsLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPE-LEKELERLREHNKHLNENIENKLllkEEVEDLKR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  609 KLDHANKENSDVI--ELWKSKLESAIASHQQAMEELKVSF----------------NKGVGAQTAEFAELKTQMEKVKLD 670
Cdd:pfam05557  236 KLEREEKYREEAAtlELEKEKLEQELQSWVKLAQDTGLNLrspedlsrrieqlqqrEIVLKEENSSLTSSARQLEKARRE 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  671 YENEMSNL--KLKQENEKSQHLKE-IEALKAKLLEVTEEKeqtlENLKAKLESVEDQhlVEMEDTLNKLQEAEIKVSNLT 747
Cdd:pfam05557  316 LEQELAQYlkKIEDLNKKLKRHKAlVRRLQRRVLLLTKER----DGYRAILESYDKE--LTMSNYSPQLLERIEEAEDMT 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  748 KELQGK----EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENaqramqETINKLNQKEEQFALMSSELEQL 823
Cdd:pfam05557  390 QKMQAHneemEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSK------EEVDSLRRKLETLELERQRLREQ 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  824 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQ--------LELTKANE 895
Cdd:pfam05557  464 KNELEMELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLeqvlrlpeTTSTMNFK 543

                          570       580       590
                   ....*....|....*....|....*....|...
gi 2024359632  896 KAVQLQKNVEqTAQKAEQSQQETLKTHQEELKK 928
Cdd:pfam05557  544 EVLDLRKELE-SAELKNQRLKEVFQAKIQEFRD 575
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 546-842 5.08e-04

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 45.23  E-value: 5.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  546 SLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASnermgkenESLKTKLDHANkensdviELWK 625
Cdd:PLN03229   481 AMGLQERLENLREEFSKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNY--------LSLKYKLDMLN-------EFSR 545

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  626 SKlesAIASHQQAMEELKVSFNKGVgAQTAEFAELKTQMEKVK-------------LDYENEMSNLKLKQENE------- 685
Cdd:PLN03229   546 AK---ALSEKKSKAEKLKAEINKKF-KEVMDRPEIKEKMEALKaevassgassgdeLDDDLKEKVEKMKKEIElelagvl 621

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  686 KSQHLkEIEALKAKLLEVTEEkeQTLENLKAKLESVEDQHLVEMEDTLNklqeaeikvsnlTKELQGKEQKL-LDLEKNL 764
Cdd:PLN03229   622 KSMGL-EVIGVTKKNKDTAEQ--TPPPNLQEKIESLNEEINKKIERVIR------------SSDLKSKIELLkLEVAKAS 686

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632  765 SAVN-QVKDSLEKELQLLKEKFTSAVDGAEnaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQ 842
Cdd:PLN03229   687 KTPDvTEKEKIEALEQQIKQKIAEALNSSE-----LKEKFEELEAELAAARETAAESNGSLKNDDDKEEDSKEDGSRVE 760
mukB PRK04863
chromosome partition protein MukB;
491-1298 5.14e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.33  E-value: 5.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  491 KADKLQRELEDTRVATVSEKSRIMELERDLAlrvkEVAELRGRLESSkhIDDVDTSLSLLQEISSLQEKmaaaGKEHQRE 570
Cdd:PRK04863   287 EALELRRELYTSRRQLAAEQYRLVEMARELA----ELNEAESDLEQD--YQAASDHLNLVQTALRQQEK----IERYQAD 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  571 MSSLKEKFESSEEAlRKEIKTLSASNERMGKENE----SLKTKLdhankenSDVIELWKSKLESAIASHQ--QAMEELKV 644
Cdd:PRK04863   357 LEELEERLEEQNEV-VEEADEQQEENEARAEAAEeevdELKSQL-------ADYQQALDVQQTRAIQYQQavQALERAKQ 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  645 -----SFN-KGVGAQTAEF-AELKTQMEKVkLDYENEMSNlklkQENEKSQHLKEIEALKAKLLEVteEKEQTLENLKAK 717
Cdd:PRK04863   429 lcglpDLTaDNAEDWLEEFqAKEQEATEEL-LSLEQKLSV----AQAAHSQFEQAYQLVRKIAGEV--SRSEAWDVAREL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  718 L-ESVEDQHLVEmedtlnklqeaeikvsnltkELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDgAENAQ 796
Cdd:PRK04863   502 LrRLREQRHLAE--------------------QLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE-LEQLQ 560

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  797 RAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKSSGDSSAQLMKMNDEL 876
Cdd:PRK04863   561 EELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLR----EQSGEEFEDSQDVTEYMQQL 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  877 RLKERQLEQIQLELTKANEkavQLQKNVEQTAQkAEQSQQETLKTHQEELK-----------KMQD-------------- 931
Cdd:PRK04863   637 LERERELTVERDELAARKQ---ALDEEIERLSQ-PGGSEDPRLNALAERFGgvllseiyddvSLEDapyfsalygparha 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  932 ----QLTDMKKQMETSQNQYKDLQakyeketseMITkhdADIKGFKQNLLDAEEALKA-AQKKND-EL------------ 993
Cdd:PRK04863   713 ivvpDLSDAAEQLAGLEDCPEDLY---------LIE---GDPDSFDDSVFSVEELEKAvVVKIADrQWrysrfpevplfg 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  994 ----ETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLA---------QERNTLKLEKESLLSQHlemE 1060
Cdd:PRK04863   781 raarEKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeaelRQLNRRRVELERALADH---E 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1061 SKIllvQQDREELWTKNEELNSENK-----KILK----QKEAAEAKSRQESTEKVAL-ISEKSKLLSEIETAQADLLKIT 1130
Cdd:PRK04863   858 SQE---QQQRSQLEQAKEGLSALNRllprlNLLAdetlADRVEEIREQLDEAEEAKRfVQQHGNALAQLEPIVSVLQSDP 934

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1131 QENDALRSSESTLLQQLKELQANKDAVD--VACQKH-----------------IKEREELEHYQKLLEENDRVIKDKDD- 1190
Cdd:PRK04863   935 EQFEQLKQDYQQAQQTQRDAKQQAFALTevVQRRAHfsyedaaemlaknsdlnEKLRQRLEQAEQERTRAREQLRQAQAq 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1191 ------VIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthialKNEIDCLLQTNRSLQSEKEMLLKSREE 1264
Cdd:PRK04863  1015 laqynqVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR------RDELHARLSANRSRRNQLEKQLTFCEA 1088

                          890       900       910
                   ....*....|....*....|....*....|....
gi 2024359632 1265 lcvslantANENQALKLRKdeMQTELETEREKLE 1298
Cdd:PRK04863  1089 --------EMDNLTKKLRK--LERDYHEMREQVV 1112
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2079-2096 5.54e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.54e-04
                           10
                   ....*....|....*...
gi 2024359632 2079 RLFCDICGCFDlHDTEDC 2096
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
46 PHA02562
endonuclease subunit; Provisional
 915-1181 5.59e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 5.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  915 QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsEMITKHDADIKGFKQNLLDAEEALKAAQKkndELE 994
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLNLVM---DIE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  995 TQAEELKKQAEQAKSLSSVLASARKEIELMSDK------MRDLISEKETLAQERNTLKlekesllsqhlEMESKILLVQQ 1068
Cdd:PHA02562   252 DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLK-----------ELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1069 DREELWTKNEELNSENKKILKQKeaaeAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEndalrssestllqqLK 1148
Cdd:PHA02562   321 AIDELEEIMDEFNEQSKKLLELK----NKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE--------------LA 382

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2024359632 1149 ELQANKDAVDVACQKHIKEREELEHYQKLLEEN 1181
Cdd:PHA02562   383 KLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 658-1103 6.20e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 44.95  E-value: 6.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  658 AELKTQMEKVKLDYENEMSNLKLKQENEKSQhLKEIEALKAKLLEVTEEKEQTLENLKAKLESVedqhLVEMEDTLNKLQ 737
Cdd:COG5185    158 TGIIKDIFGKLTQELNQNLKKLEIFGLTLGL-LKGISELKKAEPSGTVNSIKESETGNLGSEST----LLEKAKEIINIE 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  738 EAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMS 817
Cdd:COG5185    233 EALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  818 SELEQLKSN--LTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNdELRLKERQLEQIQLELTKANE 895
Cdd:COG5185    313 SLEEQLAAAeaEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEV-ELSKSSEELDSFKDTIESTKE 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  896 KAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKgfkqn 975
Cdd:COG5185    392 SLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE----- 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  976 lldaeealKAAQKKNDELETQAEELKKQAEQAKS-LSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLS 1054
Cdd:COG5185    467 --------EAYDEINRSVRSKKEDLNEELTQIESrVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHI 538

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359632 1055 QHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQEST 1103
Cdd:COG5185    539 LALENLIPASELIQASNAKTDGQAANLRTAVIDELTQYLSTIESQQARE 587
PRK12704 PRK12704
phosphodiesterase; Provisional
 658-779 6.24e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 6.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  658 AELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLevteEKEQTLENLKAKLESvEDQHLVEMEDTLNKLQ 737
Cdd:PRK12704    49 KEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL----QKEENLDRKLELLEK-REEELEKKEKELEQKQ 123

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359632  738 EaeiKVSNLTKELQGKEQKLLD-LEK--NLS---AVNQVKDSLEKELQ 779
Cdd:PRK12704   124 Q---ELEKKEEELEELIEEQLQeLERisGLTaeeAKEILLEKVEEEAR 168
mukB PRK04863
chromosome partition protein MukB;
691-1018 6.79e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 6.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  691 KEIEALKAKLLEVTEEKE------QTLENLKAKLESVEDQHL---------VEMEDTLNKLQEAEIKVSNLTKELQGKEQ 755
Cdd:PRK04863   786 KRIEQLRAEREELAERYAtlsfdvQKLQRLHQAFSRFIGSHLavafeadpeAELRQLNRRRVELERALADHESQEQQQRS 865

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  756 KLLDLEKNLSAVNQV--------KDSLEKELQLLKEKftsaVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLksnl 827
Cdd:PRK04863   866 QLEQAKEGLSALNRLlprlnllaDETLADRVEEIREQ----LDEAEEAKRFVQQHGNALAQLEPIVSVLQSDPEQF---- 937

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  828 tvmETKLKEREEREQQLTEAKVKLEnDIAEIMKS----SGDSSAQLMKMNDEL--RLKERqLEQIQLELTKANEKAVQLQ 901
Cdd:PRK04863   938 ---EQLKQDYQQAQQTQRDAKQQAF-ALTEVVQRrahfSYEDAAEMLAKNSDLneKLRQR-LEQAEQERTRAREQLRQAQ 1012

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  902 ------KNVEQTAQKAEQSQQETLKTHQEELKKMQDQLT-DMKKQMETSQNQ-YKDLQAKYEKETSemitkhdadikgFK 973
Cdd:PRK04863  1013 aqlaqyNQVLASLKSSYDAKRQMLQELKQELQDLGVPADsGAEERARARRDElHARLSANRSRRNQ------------LE 1080

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359632  974 QNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK-SLSSVLASAR 1018
Cdd:PRK04863  1081 KQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNAKaGWCAVLRLVK 1126
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 787-1017 7.05e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 7.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  787 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDsS 866
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE-R 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  867 AQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLKTHQEELKKMQDQLTDMKKQMETSQ 944
Cdd:COG3883     92 ARALYRSGGSVSYLDVLLGSE-SFSDFLDRLSALSKIADADADLLEElkADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359632  945 NQYKDLQAKYEKETsemitkhdADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1017
Cdd:COG3883    171 AELEAQQAEQEALL--------AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 702-887 7.30e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.82  E-value: 7.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  702 EVTEEKEQtLENLKAKLESVEdqhlvemedtlnklQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKElqlL 781
Cdd:PRK00409   510 LIGEDKEK-LNELIASLEELE--------------RELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEE---A 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  782 KEKFTSAVdgaENAQRAMQETINKLN--QKEEQFALMSSELE----QLKSNLTVMETKLKEREEREQQLT---EAKVKLE 852
Cdd:PRK00409   572 EKEAQQAI---KEAKKEADEIIKELRqlQKGGYASVKAHELIearkRLNKANEKKEKKKKKQKEKQEELKvgdEVKYLSL 648

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 2024359632  853 NDIAEIMKSSGDSSAQ----LMKMndelRLKERQLEQIQ 887
Cdd:PRK00409   649 GQKGEVLSIPDDKEAIvqagIMKM----KVPLSDLEKIQ 683
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 724-906 8.40e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 8.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  724 QHLVEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETI 803
Cdd:COG1579      7 RALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  804 NklnqkEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmndelrlkERQL 883
Cdd:COG1579     87 N-----NKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL----------DEEL 151

                          170       180
                   ....*....|....*....|...
gi 2024359632  884 EQIQLELTKANEKAVQLQKNVEQ 906
Cdd:COG1579    152 AELEAELEELEAEREELAAKIPP 174
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1525-1788 8.54e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 8.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1525 ILNRERTELQDKCQKLtG--EVENMKENLTVEkkaRILDKESfllERMELQNNIGFLEKEVEemreknKEFLTEKELLVQ 1602
Cdd:PRK05771    13 TLKSYKDEVLEALHEL-GvvHIEDLKEELSNE---RLRKLRS---LLTKLSEALDKLRSYLP------KLNPLREEKKKV 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1603 EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScVSVMLDELQHK-------YEVTEKEKM 1675
Cdd:PRK05771    80 SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGFkyvsvfvGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1676 ELVQENESLHAEWKS-------LVIINEeilkekeklsKEYYKLHEKVVAlleqtDADFScRLLVSEGKH--ELLLEEMS 1746
Cdd:PRK05771   159 ELKLESDVENVEYIStdkgyvyVVVVVL----------KELSDEVEEELK-----KLGFE-RLELEEEGTpsELIREIKE 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359632 1747 NLALKLREIERLQAQTfmqKFEADKRAEEVLQTMEKVTKEKD 1788
Cdd:PRK05771   223 ELEEIEKERESLLEEL---KELAKKYLEELLALYEYLEIELE 261
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
760-1079 9.22e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 9.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  760 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 839
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  840 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETL 919
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  920 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEE 999
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1000 LKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1079
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1817-2049 1.00e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1817 MLKQNNLKNEEELTKSKELLNlenKKVEELKKEFEAL--KLAAAQKSQQLAALQEENVKLAEELGRSRDEVTshqKLEEE 1894
Cdd:COG3206    161 YLEQNLELRREEARKALEFLE---EQLPELRKELEEAeaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLA---EARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1895 RSVLNNQLLEMKKSLPSN-----TLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGEnaSAKTLQ 1969
Cdd:COG3206    235 LAEAEARLAALRAQLGSGpdalpELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ--LQQEAQ 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1970 SVVKTLESDKLKLEEKVKNLEQKLKAKSEQpltvtspsgdiAANLLQDES-AEDKQQEIDFLNSVIVDLQRRNEELNLKI 2048
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEAR-----------LAELPELEAeLRRLEREVEVARELYESLLQRLEEARLAE 381


                   .
gi 2024359632 2049 Q 2049
Cdd:COG3206    382 A 382
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 991-1378 1.36e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.52  E-value: 1.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  991 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1070
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1071 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1150
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRL 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1151 QANKDAVDVACQKHIKEREELEhyqKLLEENDRVIkdkDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1230
Cdd:pfam19220  180 QALSEEQAAELAELTRRLAELE---TQLDATRARL---RALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEAL 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1231 KSTHIALkneiDCLLQTNRSLQSEKEMLLKSREElcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKAS 1310
Cdd:pfam19220  254 TARAAAT----EQLLAEARNQLRDRDEAIRAAER---RLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEER 326

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632 1311 LSSLSNFLEEmKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETA 1378
Cdd:pfam19220  327 AEMLTKALAA-KDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERALAQGA 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1089-1328 1.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1089 KQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQLKELQANkdavdvacqkhikeR 1168
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAELAEL--------------E 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1169 EELEHYQKLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAerdsaqekdldLKSTHIALKNEIDCLLQT 1247
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLQY-----------LKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1248 NRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREA 1327
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   .
gi 2024359632 1328 S 1328
Cdd:COG4942    239 A 239
PRK12704 PRK12704
phosphodiesterase; Provisional
 1751-1873 1.42e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1751 KLREIERlQAQTFMQkfEADKRAEEVLQtmEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdMLKQNNLKN----- 1825
Cdd:PRK12704    32 KIKEAEE-EAKRILE--EAKKEAEAIKK--EALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL-LQKEENLDRklell 105

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359632 1826 ---EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1873
Cdd:PRK12704   106 ekrEEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK 156
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
992-1593 1.42e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  992 ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDkMRDLISEKETLAQERNTLKLEKESLlsQHLEMESKILLVQQDRE 1071
Cdd:COG4913    222 DTFEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1072 ELwtkneelnsenkkilkQKEAAEAKSRQESTEKvalisekskllsEIETAQADLLKITQendALRSSESTLLQQLKELQ 1151
Cdd:COG4913    299 EL----------------RAELARLEAELERLEA------------RLDALREELDELEA---QIRGNGGDRLEQLEREI 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1152 ANKdavdvacQKHIKERE-ELEHYQKLLEendrvikdkdDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1230
Cdd:COG4913    348 ERL-------ERELEERErRRARLEALLA----------ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1231 KSTHIALKNEIDCLLQTNRSLQSEK----EMLLKSREELCvslantanenQALKLRKDE-------MQTELETER----- 1294
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKsnipARLLALRDALA----------EALGLDEAElpfvgelIEVRPEEERwrgai 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1295 ---------------EKLEKMTK--DNMDLKASLSS--LSNFLEEMKSSREASNS--EKIHLLQEALFASEQRLLAER-- 1351
Cdd:COG4913    481 ervlggfaltllvppEHYAAALRwvNRLHLRGRLVYerVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAWLEAELGRRfd 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1352 -------EELVNENKAVT-EKLTKATADA-------------VLAETAfTEKINELNLEKesvfskslqfekhnEALLRE 1410
Cdd:COG4913    561 yvcvdspEELRRHPRAITrAGQVKGNGTRhekddrrrirsryVLGFDN-RAKLAALEAEL--------------AELEEE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1411 KDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIAcrsdLSDLLKE 1490
Cdd:COG4913    626 LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-----IAELEAELERLDASSDDLAA----LEEQLEE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1491 AQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK-LTGEVENMKENLTVEKKARILdKESFLLER 1569
Cdd:COG4913    697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVEREL-RENLEERI 775

                          650       660
                   ....*....|....*....|....*
gi 2024359632 1570 MELQNNIGFLEKEVEE-MREKNKEF 1593
Cdd:COG4913    776 DALRARLNRAEEELERaMRAFNREW 800
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 349-614 1.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  349 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlEMEAKMDQLRAMVEAADREKVEL 428
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----------ALERRIAALARRIRALEQELAAL 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  429 LNQLEEEKRKVEDLQFRVEeesitkgdlERKRQISEDPENTQTKLEHARIKeleqsLLFEKTKADKLQRELEDTRVATVS 508
Cdd:COG4942     82 EAELAELEKEIAELRAELE---------AQKEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAVRRLQYLKYLAPA 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  509 EKSRIMELERDLAlrvkEVAELRGRLESSKhiddvDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSE---EAL 585
Cdd:COG4942    148 RREQAEELRADLA----ELAALRAELEAER-----AELEALLAELEEERAALEALKAERQKLLARLEKELAELAaelAEL 218

                          250       260
                   ....*....|....*....|....*....
gi 2024359632  586 RKEIKTLSASNERMGKENESLKTKLDHAN 614
Cdd:COG4942    219 QQEAEELEALIARLEAEAAAAAERTPAAG 247
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
755-1229 1.78e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  755 QKLLDLEKNLSAVNQVKDSLEkELQLLKEKFTSAVDGAEnAQRAMQETINKLnQKEEQFALMSSELEQLKSNLTVMETKL 834
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLA-ELEYLRAALRLW-FAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  835 KEREEREQQLTEAKVKLENDIAEimkSSGDSSAQLMKmndELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ--KAE 912
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRG---NGGDRLEQLER---EIERLERELEERERRRARLEALLAALGLPLPASAEefAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  913 QSQ-QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAkyeketsemitkhdaDIKGFKQN-------LLDAEEALK 984
Cdd:COG4913    386 RAEaAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---------------EIASLERRksniparLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  985 AA-QKKNDELETQAEELKKQAEQAK--------------SL---SSVLASARKEIE-------LMSDKMRDLISEKETLA 1039
Cdd:COG4913    451 EAlGLDEAELPFVGELIEVRPEEERwrgaiervlggfalTLlvpPEHYAAALRWVNrlhlrgrLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1040 QERNTL--KLE-KESLLSQHLEME--SKILLVQQDREE--------------------LWTKNEE----------LNSEN 1084
Cdd:COG4913    531 LDPDSLagKLDfKPHPFRAWLEAElgRRFDYVCVDSPEelrrhpraitragqvkgngtRHEKDDRrrirsryvlgFDNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1085 KKILKQKEAAEAKSR-QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL---QQLKELQANKDAVDVA 1160
Cdd:COG4913    611 KLAALEAELAELEEElAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSDDLAAL 690

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632 1161 cqkhikeREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLD 1229
Cdd:COG4913    691 -------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-699 1.95e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  463 SEDPENTQTKLE--HARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELERDLALRVKEVAELRGRlesskhI 540
Cdd:COG4942     19 ADAAAEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE------I 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  541 DDVDTSLSLLQEisSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKeIKTLSASNERMGKENESLKTKLDHANKENSDv 620
Cdd:COG4942     93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALLLSPEDFLDAVRR-LQYLKYLAPARREQAEELRADLAELAALRAE- 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632  621 IELWKSKLESAIASHQQAMEELKvsfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAK 699
Cdd:COG4942    169 LEAERAELEALLAELEEERAALE--------ALKAERQKLLARLEKELAELAAELAELQ-QEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1327-1549 2.18e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1327 ASNSEKIHLLQEALFASEQRLlAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEA 1406
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEI-AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1407 LLREKDELERKYSELLDE--KKSLENAFSDMKREQELDFSAKRL--LVQENTTLKYSIEALEEELKKKNLENQELIACRS 1482
Cdd:COG4942     95 LRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632 1483 DLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKE 1549
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1382-1849 2.59e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1382 KINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIE 1461
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1462 ALEEELKK-----KNLENQeLIACRSDLSDLLKE-AQDARRTLENELAAVSHAKQVLSS-------SFNTCSSDIEILNR 1528
Cdd:TIGR04523  271 EKQKELEQnnkkiKELEKQ-LNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNqisqnnkIISQLNEQISQLKK 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1529 ERTELQDKCQKLTGEVENMKENLTVEKKarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSE 1608
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKK----ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1609 TKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM-------LDELQHKYEVTEKEKMELVQEN 1681
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEK 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1682 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADfscrllVSEGKHELLLEEMSNLALKLREIERLQAQ 1761
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD------DFELKKENLEKEIDEKNKEIEELKQTQKS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1762 TFMQKFEADKRAEEVLQTMEKVTKEKdaihQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENK 1841
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIKEI----EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655


                   ....*...
gi 2024359632 1842 KVEELKKE 1849
Cdd:TIGR04523  656 EIRNKWPE 663
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1571-1969 2.79e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1571 ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAele 1650
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1651 dvhscvsvmLDELQHKYEVTEKEKMELVQENESLHAEWKSLviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCR 1730
Cdd:COG4717    127 ---------LLPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLSLATEEE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1731 LLVSEGKHELLLEEMSNL--ALKLREIERLQAQTFMQKFEADKRAEEVLQTMEK-------------------------- 1782
Cdd:COG4717    194 LQDLAEELEELQQRLAELeeELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallallglggsllslil 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1783 -------------------VTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1843
Cdd:COG4717    274 tiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1844 EELKKEFEALKLAAAQKSQQlAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESTLKKEI 1923
Cdd:COG4717    354 REAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEEL 430

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359632 1924 DEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQ 1969
Cdd:COG4717    431 EEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
PTZ00121 PTZ00121
MAEBL; Provisional
 1753-1995 2.87e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1753 REIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKS 1832
Cdd:PTZ00121  1278 RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1833 KELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSN 1912
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1913 TLRESTLKKEIDEERASLQKSISDtsalITQKDEELEKLRNeitvLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQK 1992
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAEE----AKKKAEEAKKADE----AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509


                   ...
gi 2024359632 1993 LKA 1995
Cdd:PTZ00121  1510 KKA 1512
PRK11281 PRK11281
mechanosensitive channel MscK;
801-1171 3.06e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 3.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  801 ETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND------ 874
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLStlslrq 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  875 -ELRLKER--QLEQIQLELTKANEKAVQLQKNVEQtAQKA-EQSQQETlkthqEELKKMQDQLTDMKKQMETSQnqykdl 950
Cdd:PRK11281   126 lESRLAQTldQLQNAQNDLAEYNSQLVSLQTQPER-AQAAlYANSQRL-----QQIRNLLKGGKVGGKALRPSQ------ 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  951 QAKYEKETSEMITKHDadikgFKQNLLDAEEALKA-AQKKNDELetqAEELKKQAEQAKSLSSVLASarKEIELMSDKMR 1029
Cdd:PRK11281   194 RVLLQAEQALLNAQND-----LQRKSLEGNTQLQDlLQKQRDYL---TARIQRLEHQLQLLQEAINS--KRLTLSEKTVQ 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1030 DLISEKETLAQERNTLkLEKESLLSQHLemeSKILLVQQDR------EELWTKN--EELNSENKKILKQKEAAEAK---S 1098
Cdd:PRK11281   264 EAQSQDEAARIQANPL-VAQELEINLQL---SQRLLKATEKlntltqQNLRVKNwlDRLTQSERNIKEQISVLKGSlllS 339

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359632 1099 RQESTEKVALISekSKLLSEIETAQADL----LKITQENDALrSSESTLLQQLKELQANK--DAVDVACQKHIKEREEL 1171
Cdd:PRK11281   340 RILYQQQQALPS--ADLIEGLADRIADLrleqFEINQQRDAL-FQPDAYIDKLEAGHKSEvtDEVRDALLQLLDERREL 415
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 749-965 3.07e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 42.25  E-value: 3.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  749 ELQGK-EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQ 822
Cdd:cd22654    101 KLQSQlQTIQNSMEQTSSNLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEV 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  823 LKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQK 902
Cdd:cd22654    181 GDGSINIGKQVFTITITTATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTL 257

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359632  903 NVEQTAQKAE--QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 965
Cdd:cd22654    258 VEDQVNGFTEliKRQIATLENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
PRK11281 PRK11281
mechanosensitive channel MscK;
1773-1944 3.19e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1773 AEEVLQTMEKVTKEKDAIHQEK---------IETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKskellnLENKKV 1843
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKlvqqdleqtLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA------LKDDND 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1844 EELKKEFEALKLAA-----AQKSQQLAALQE------------------------ENVKLAEEL---------GRSRDEV 1885
Cdd:PRK11281   112 EETRETLSTLSLRQlesrlAQTLDQLQNAQNdlaeynsqlvslqtqperaqaalyANSQRLQQIrnllkggkvGGKALRP 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359632 1886 TSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEID---EERASLQKSISDTSALITQK 1944
Cdd:PRK11281   192 SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltARIQRLEHQLQLLQEAINSK 253
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1792-1910 3.41e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1792 QEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQ-LAALQE 1869
Cdd:PRK00409   515 KEKLNELiASLEELERELEQKAEEAEALLKEAEKLKEEL----------EEKKEKLQEEEDKLLEEAEKEAQQaIKEAKK 584

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2024359632 1870 ENVKLAEELGRSRDEVTSHQK---LEEERSVLNNQLLEMKKSLP 1910
Cdd:PRK00409   585 EADEIIKELRQLQKGGYASVKaheLIEARKRLNKANEKKEKKKK 628
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 1558-1984 3.66e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 42.63  E-value: 3.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1558 RILDKESFLLERME-----------LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETE 1626
Cdd:pfam15818    1 QLLDFKTSLLEALEelrmrreaetqYEEQIGKIIVETQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQMKMCALEEEK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1627 ---QLASK-----IEQLKSDFTSLSVSKAELEDVhscVSVMLDELQ----------------HKYEVTEKEKMELVQEN- 1681
Cdd:pfam15818   81 gkyQLATEikekeIEGLKETLKALQVSKYSLQKK---VSEMEQKLQlhllakedhhkqlneiEKYYATITGQFGLVKENh 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1682 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvvalLEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQ 1761
Cdd:pfam15818  158 GKLEQNVQEAIQLNKRLSALNKKQESEICSLKKE----LKKVTSDLIKSKVTCQYKMG---EENINLTIKEQKFQELQER 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1762 TFMQkfeadkraeevLQTMEKVTKEKDAIHQEKIETLAS-------LENSRQTNEKLQNELDMLKQNN--LKNEEELTKS 1832
Cdd:pfam15818  231 LNME-----------LELNKKINEEITHIQEEKQDIIISfqhmqqlLQQQTQANTEMEAELKALKENNqtLERDNELQRE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1833 K------ELLNLENKKVEEL---KKEFEALKLAAAQKSQQLAALQEENVKLAEElgrsRDEVTSHQKLEEERSVLNNQLL 1903
Cdd:pfam15818  300 KvkeneeKFLNLQNEHEKALgtwKKHVEELNGEINEIKNELSSLKETHIKLQEH----YNKLCNQKKFEEDKKFQNVPEV 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1904 EMKKS-LPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKL 1982
Cdd:pfam15818  376 NNENSeMSTEKSENLIIQKYNSEQEIREENTKSFCSDTEYRETEKKKGPPVEEIIIEDLQVLEKSFKNEIDTSVPQDKNQ 455


                   ..
gi 2024359632 1983 EE 1984
Cdd:pfam15818  456 SE 457
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1768-1908 3.91e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1768 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1847
Cdd:pfam06160  267 EIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGL----EKQLEELE 342

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1848 KEFEALKLAAAQKSQ--------------QLAALQEENVKLAEELGRSR-DEVTSHQKLEEERSVLNNQLLEMKKS 1908
Cdd:pfam06160  343 KRYDEIVERLEEKEVayselqeeleeileQLEEIEEEQEEFKESLQSLRkDELEAREKLDEFKLELREIKRLVEKS 418
PRK12704 PRK12704
phosphodiesterase; Provisional
 656-766 4.15e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  656 EFAELKTQMEKVKLDYENEMSNL--KLKQE----NEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEM 729
Cdd:PRK12704    65 EIHKLRNEFEKELRERRNELQKLekRLLQKeenlDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 2024359632  730 EdtlnklqeaeiKVSNLTKElQGKEQKLLDLEKNLSA 766
Cdd:PRK12704   145 E-----------RISGLTAE-EAKEILLEKVEEEARH 169
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 891-1010 4.28e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.64  E-value: 4.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  891 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMkkqmetsQNQYKDLQAKYEKETsemitkhdadik 970
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATA-------QKELANAQAQALQTA------------ 316

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2024359632  971 gfKQNLLDAEEALKAAQKKNDELETQAEELK-KQAEQAKSL 1010
Cdd:TIGR04320  317 --QNNLATAQAALANAEARLAKAKEALANLNaDLAKKQAAL 355
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
793-1135 4.53e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 4.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  793 ENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKM 872
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  873 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 952
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEE-LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  953 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLI 1032
Cdd:COG4372    165 ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALEL 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1033 SEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEK 1112
Cdd:COG4372    245 EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324

                          330       340
                   ....*....|....*....|...
gi 2024359632 1113 SKLLSEIETAQADLLKITQENDA 1135
Cdd:COG4372    325 AKKLELALAILLAELADLLQLLL 347
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 661-1041 4.55e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 42.09  E-value: 4.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  661 KTQMEKVKLdyeNEMSNLKLKQENEKSQHLKEIEALKAKllevtEEKEQTLENLKAKLES--------------VEDQHL 726
Cdd:PRK10246   451 NVTQEQTQR---NAALNEMRQRYKEKTQQLADVKTICEQ-----EARIKDLEAQRAQLQAgqpcplcgstshpaVEAYQA 522

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  727 VEMEDTLNKLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDgAENAQRAMQETINKL 806
Cdd:PRK10246   523 LEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCA-SLNITLQPQDDIQPW 601

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  807 NQKEEQFalmSSELEQLKSNLTvMETKLKEREERE----QQLTEAKVKLENDIAEIMKS---SGDSSAQLMKMNDELRlk 879
Cdd:PRK10246   602 LDAQEEH---ERQLRLLSQRHE-LQGQIAAHNQQIiqyqQQIEQRQQQLLTALAGYALTlpqEDEEASWLATRQQEAQ-- 675

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  880 erQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETlKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETS 959
Cdd:PRK10246   676 --SWQQRQNELTALQNRIQQLTPLLETLPQSDDLPHSEE-TVALDNWRQVHEQCLSLHSQLQTLQQQDVLEAQRLQKAQA 752

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  960 EMITKHDA----DIKGFKQNLLDAEEALKaaqkkndeLETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEK 1035
Cdd:PRK10246   753 QFDTALQAsvfdDQQAFLAALLDEETLTQ--------LEQLKQNLENQRQQAQTLVTQTAQALAQHQQHRPDGLDLTVTV 824


                   ....*.
gi 2024359632 1036 ETLAQE 1041
Cdd:PRK10246   825 EQIQQE 830
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 800-986 4.59e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  800 QETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLM--KMNDELR 877
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  878 LKERQLEQIQLELTKANEKAVQLQKNVEQtaqkaeqsqqetlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKE 957
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEE---------------LEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170       180
                   ....*....|....*....|....*....
gi 2024359632  958 TSEMITKHDADIKGFKQNLLDAEEALKAA 986
Cdd:COG1579    158 LEELEAEREELAAKIPPELLALYERIRKR 186
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1768-1909 4.71e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1768 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1847
Cdd:PRK04778   286 EIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQL----EKQLESLE 361

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359632 1848 KEFEALKLAAAQKSQ---QLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEMKKSL 1909
Cdd:PRK04778   362 KQYDEITERIAEQEIaysELQEELEEILKQLEEIEKEQEKLSEMlQGLRKDELEAREKLERYRNKL 427
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 355-709 4.81e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 4.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  355 QEALK-EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDgHDRHVLEMEAKMDQLRamveaadrekvellnqLE 433
Cdd:pfam17380  298 QERLRqEKEEKAREVERRRKLEEAEKARQ----AEMDRQAAIYAE-QERMAMERERELERIR----------------QE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  434 EEKRKVEdlqfRVEEESITkgdlerkrqisedpentqtkLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRi 513
Cdd:pfam17380  357 ERKRELE----RIRQEEIA--------------------MEISRMRELERLQMERQQKNERVRQELEAARKVKILEEER- 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  514 melERDLALRVKEVAELRGRLESSKhiddvdtslsllqeisslqekmaaagkehQREMSSLKEKFESSEEALRKEIKTLS 593
Cdd:pfam17380  412 ---QRKIQQQKVEMEQIRAEQEEAR-----------------------------QREVRRLEEERAREMERVRLEEQERQ 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  594 ASNERMGKENESLKTK---LDHANKENSDVIELWKSKLESAIASHQQAMEElkvsfnkgvgaQTAEFAELKTQMEKVKLD 670
Cdd:pfam17380  460 QQVERLRQQEEERKRKkleLEKEKRDRKRAEEQRRKILEKELEERKQAMIE-----------EERKRKLLEKEMEERQKA 528

                          330       340       350
                   ....*....|....*....|....*....|....*....
gi 2024359632  671 YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQ 709
Cdd:pfam17380  529 IYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSR 567
PLN02939 PLN02939
transferase, transferring glycosyl groups
 761-1128 5.30e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  761 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRamqeTINKLNQKEEQfAL-----MSSELEQLKSNLTVMETKLK 835
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEK----NILLLNQARLQ-ALedlekILTEKEALQGKINILEMRLS 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  836 EREEREQQLTEAKVKLEndiaeimkssgdssaqlmkmndelrLKERQLEQIQLELTK--ANEKAVQLQKNVEQTAQKAEQ 913
Cdd:PLN02939   181 ETDARIKLAAQEKIHVE-------------------------ILEEQLEKLRNELLIrgATEGLCVHSLSKELDVLKEEN 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  914 SqqeTLKTHQEELKKMQDQLTDMKKQMetsqnqykdlqAKYEKETSEMitkhDADIKGFKQNLLDAEEAL--------KA 985
Cdd:PLN02939   236 M---LLKDDIQFLKAELIEVAETEERV-----------FKLEKERSLL----DASLRELESKFIVAQEDVsklsplqyDC 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  986 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD-----LISEKETLAQERntLKLEKESLLSQHLEME 1060
Cdd:PLN02939   298 WWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEanvskFSSYKVELLQQK--LKLLEERLQASDHEIH 375

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359632 1061 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSrqESTEKVALISEKSKLLSEIETAQADLLK 1128
Cdd:PLN02939   376 SYIQLYQESIKEFQDTLSKLKEESKKRSLEHPADDMPS--EFWSRILLLIDGWLLEKKISNNDAKLLR 441
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 673-1055 5.82e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  673 NEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQtLENLKAKLEsvedQHLVEMEDTLNKLQEAeikvSNLTKELQG 752
Cdd:COG3096    281 RELSERALELRRELFGARRQLAEEQYRLVEMARELEE-LSARESDLE----QDYQAASDHLNLVQTA----LRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  753 KEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSA---VDGAENA----QRAM----------QETINKLNQKEEQFAL 815
Cdd:COG3096    352 YQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAeeeVDSLKSQladyQQALdvqqtraiqyQQAVQALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  816 MSSELEQLksnltvmETKLKEREEREQQLTEAKVKLEN--DIAEIMKSSGDSSAQLM-KMNDELrlkerqleqiqlELTK 892
Cdd:COG3096    432 PDLTPENA-------EDYLAAFRAKEQQATEEVLELEQklSVADAARRQFEKAYELVcKIAGEV------------ERSQ 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  893 ANEKAVQLQKnvEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQM-ETSQNQYKDLQAKYEKEtsEMITKHDADIKG 971
Cdd:COG3096    493 AWQTARELLR--RYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeEFCQRIGQQLDAAEELE--ELLAELEAQLEE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  972 FKQNLLDAEEALKAAQKKNDELETQAEELKKQA-------EQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNT 1044
Cdd:COG3096    569 LEEQAAEAVEQRSELRQQLEQLRARIKELAARApawlaaqDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDE 648

                          410
                   ....*....|.
gi 2024359632 1045 LKLEKESLLSQ 1055
Cdd:COG3096    649 LAARKQALESQ 659
PRK11281 PRK11281
mechanosensitive channel MscK;
948-1251 5.95e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  948 KDLQAKYEKETSemITKHDADIKGFKQNLLDAEEALKAAQKKNDELEtqaeELKKQAEQAKSLssvLASARKEIELMSDk 1027
Cdd:PRK11281    39 ADVQAQLDALNK--QKLLEAEDKLVQQDLEQTLALLDKIDRQKEETE----QLKQQLAQAPAK---LRQAQAELEALKD- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1028 mrdliSEKETLAQERNTLKLEkesllsqhlEMESKILLVQQDREELwtkNEELNSENKKILKQkeaaeaksrQESTEKV- 1106
Cdd:PRK11281   109 -----DNDEETRETLSTLSLR---------QLESRLAQTLDQLQNA---QNDLAEYNSQLVSL---------QTQPERAq 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1107 ALISEKSKLLSEIETaqadLLKITQEND-ALRSSESTLLQ------------QLKELQANKDAVDVACQKHIKEREE--- 1170
Cdd:PRK11281   163 AALYANSQRLQQIRN----LLKGGKVGGkALRPSQRVLLQaeqallnaqndlQRKSLEGNTQLQDLLQKQRDYLTARiqr 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1171 LEHYQKLLEE--NDRVIKDKDDVIQRLQSSyDDLARNQ--RELLQEVSILTAERD---SAQEKDLDLKSTHIALKNEIDC 1243
Cdd:PRK11281   239 LEHQLQLLQEaiNSKRLTLSEKTVQEAQSQ-DEAARIQanPLVAQELEINLQLSQrllKATEKLNTLTQQNLRVKNWLDR 317


                   ....*...
gi 2024359632 1244 LLQTNRSL 1251
Cdd:PRK11281   318 LTQSERNI 325
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1543-2052 7.36e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.26  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1543 EVENMKENLTVEKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIkEKMILY 1622
Cdd:pfam05557    6 ESKARLSQLQNEKKQMELEHKR---ARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQA-ELNRLK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1623 KETEQLASKIEQLKSDftslsvSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLhaewkslviinEEILKEK 1702
Cdd:pfam05557   82 KKYLEALNKKLNEKES------QLADAREVISCLKNELSELRRQIQRAELELQSTNSELEEL-----------QERLDLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1703 EKLSKEYYKLHEkvvalleqtdadfscrllvsegKHELLLEEMSNLALKLREIERlQAQTFMQKFEADKRAEEVLQTMEK 1782
Cdd:pfam05557  145 KAKASEAEQLRQ----------------------NLEKQQSSLAEAEQRIKELEF-EIQSQEQDSEIVKNSKSELARIPE 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1783 VTKEKDAIHQEKietlASLENSRQTNEKLQNELDMLKQnNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQK-- 1860
Cdd:pfam05557  202 LEKELERLREHN----KHLNENIENKLLLKEEVEDLKR-KLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlr 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1861 -----SQQLAALQEENVKLAEELG----RSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNT-------LRESTLKKEID 1924
Cdd:pfam05557  277 spedlSRRIEQLQQREIVLKEENSsltsSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKalvrrlqRRVLLLTKERD 356

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1925 EERASLQK-----SISDTSALITQKDEELEKLRNEITVLRGEnasaktLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 1999
Cdd:pfam05557  357 GYRAILESydkelTMSNYSPQLLERIEEAEDMTQKMQAHNEE------MEAQLSVAEEELGGYKQQAQTLERELQALRQQ 430

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024359632 2000 PLTVTSPSgdiaanllQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMC 2052
Cdd:pfam05557  431 ESLADPSY--------SKEEVDSLRRKLETLELERQRLREQKNELEMELERRC 475
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 548-788 7.38e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  548 SLLQEISSLQEKMAAAGKEHQREMSSLKEkFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSK 627
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAA-LERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  628 LESAIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 707
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPEDFLDAVRR-------------LQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  708 EQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 787
Cdd:COG4942    177 EALLAELEEERAALEAL-----------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                   .
gi 2024359632  788 A 788
Cdd:COG4942    246 A 246
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 999-1235 8.11e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 8.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  999 ELKKQAEQAKSLSSVLASARKeIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEmeSKILLVQQDREELWTKNE 1078
Cdd:PRK05771    34 EDLKEELSNERLRKLRSLLTK-LSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVE--EELEKIEKEIKELEEEIS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1079 ELNSENKKILKQKEAAE----------AKSRQESTE-KVALISEKSKLLSEIETAQADLLKITQEND-------ALRSSE 1140
Cdd:PRK05771   111 ELENEIKELEQEIERLEpwgnfdldlsLLLGFKYVSvFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvVLKELS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1141 STLLQQLKELQAnkDAVDVACQKHIKEReeLEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELlqevsiLTAER 1220
Cdd:PRK05771   191 DEVEEELKKLGF--ERLELEEEGTPSEL--IREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIEL 260

                          250
                   ....*....|....*
gi 2024359632 1221 DSAQEKDLDLKSTHI 1235
Cdd:PRK05771   261 ERAEALSKFLKTDKT 275
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1097-1344 8.50e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1097 KSRQESTEKVA--LISEKSKLLSEIETAQADLLKITQENDALRSSE--STLLQQLKELQANKDAVDVacqKHIKEREELE 1172
Cdd:COG3206    167 ELRREEARKALefLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEeaKLLLQQLSELESQLAEARA---ELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1173 HYQKLLEENDRVIKD--KDDVIQRLQSSYDDLARNQRELLQevsiltaerdsaqekdlDLKSTH---IALKNEIDcllQT 1247
Cdd:COG3206    244 ALRAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAELSA-----------------RYTPNHpdvIALRAQIA---AL 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1248 NRSLQSEKEMLLKSREelcvslantaNENQALKLRKDEMQTELETEREKLEKMTKD-------NMDLKASLSSLSNFLEE 1320
Cdd:COG3206    304 RAQLQQEAQRILASLE----------AELEALQAREASLQAQLAQLEARLAELPELeaelrrlEREVEVARELYESLLQR 373

                          250       260
                   ....*....|....*....|....*.
gi 2024359632 1321 MKSSR--EASNSEKIHLLQEALFASE 1344
Cdd:COG3206    374 LEEARlaEALTVGNVRVIDPAVVPLK 399
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 995-1254 9.78e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 40.78  E-value: 9.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632  995 TQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLisekETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELW 1074
Cdd:pfam05667  301 THTEKLQFTNEAPAATSSPPTKVETEEELQQQREEEL----EELQEQLEDLESSIQELEKEIKKLESSIKQVEEELEELK 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1075 TKNEELNSENKkiLKQKEAAEAKSRQESTEKvalisekskLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANK 1154
Cdd:pfam05667  377 EQNEELEKQYK--VKKKTLDLLPDAEENIAK---------LQALVDASAQRLVELAGQWEKHRVPLIEEYRALKEAKSNK 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359632 1155 DAvdvACQKHIKEREEL-EHYQKLLEEndrvIKDKDDVIQRLQSSYDDLArnqrellQEVSiltaeRDSAQEKDLDLKST 1233
Cdd:pfam05667  446 ED---ESQRKLEEIKELrEKIKEVAEE----AKQKEELYKQLVAEYERLP-------KDVS-----RSAYTRRILEIVKN 506

                          250       260
                   ....*....|....*....|.
gi 2024359632 1234 HIALKNEIDCLLQTNRSLQSE 1254
Cdd:pfam05667  507 IKKQKEEITKILSDTKSLQKE 527
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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