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Conserved domains on  [gi|2024406904|ref|XP_015141551|]
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exocyst complex component 6B isoform X5 [Gallus gallus]

Protein Classification

SEC15 family protein( domain architecture ID 10513678)

SEC15 family protein similar to human exocyst complex component 6A/B, which are components of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
460-776 1.79e-120

Exocyst complex subunit Sec15-like;


:

Pssm-ID: 461169  Cd Length: 308  Bit Score: 365.70  E-value: 1.79e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 460 YKKMVGQFPFQDAELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 535
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 536 CLQNVIKrKNVGLTELVQIIINTTHLEKSCKFLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 615
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 616 FLQLADYDWMALEPGSRASDYLVDLIGFLRSTFA-VFTHLPGDvdahstmsgkVAQTACMSACKHLSTSLMQLLLEAEVR 694
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPES----------VKTLVYFRALDHIAESLLDLLLSPDVK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 695 QLTLGALQQFNLDVEECEQFARSGPVPGFqGDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPTCKYLRVNPTTALVLLE 774
Cdd:pfam04091 229 RINENAVSNFDLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLE 306


                  ..
gi 2024406904 775 KI 776
Cdd:pfam04091 307 KL 308
PRK03918 super family cl35229
DNA double-strand break repair ATPase Rad50;
45-231 1.77e-03

DNA double-strand break repair ATPase Rad50;


The actual alignment was detected with superfamily member PRK03918:

Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904  45 MEKLEARIRNHDREIEKmcnfhyqgfvdsitellkVRGEAQKLKNQVTDTNrKLQSEGKELIIAMEELKQCRLQQRNISA 124
Cdd:PRK03918  254 KRKLEEKIRELEERIEE------------------LKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEK 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 125 TVDKLTLCLPVLEMYSKLREQMKS------KRHYPALKTLEHLEhtylPQVSHYRFCKVMVDNIPKLREEIKEVSMSDLK 198
Cdd:PRK03918  315 RLSRLEEEINGIEERIKELEEKEErleelkKKLKELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTPEKLE 390

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2024406904 199 DFLESIRKHSDKIGETAMKQAQQQRNLDNIVSQ 231
Cdd:PRK03918  391 KELEELEKAKEEIEEEISKITARIGELKKEIKE 423
 
Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
460-776 1.79e-120

Exocyst complex subunit Sec15-like;


Pssm-ID: 461169  Cd Length: 308  Bit Score: 365.70  E-value: 1.79e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 460 YKKMVGQFPFQDAELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 535
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 536 CLQNVIKrKNVGLTELVQIIINTTHLEKSCKFLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 615
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 616 FLQLADYDWMALEPGSRASDYLVDLIGFLRSTFA-VFTHLPGDvdahstmsgkVAQTACMSACKHLSTSLMQLLLEAEVR 694
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPES----------VKTLVYFRALDHIAESLLDLLLSPDVK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 695 QLTLGALQQFNLDVEECEQFARSGPVPGFqGDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPTCKYLRVNPTTALVLLE 774
Cdd:pfam04091 229 RINENAVSNFDLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLE 306


                  ..
gi 2024406904 775 KI 776
Cdd:pfam04091 307 KL 308
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
45-231 1.77e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904  45 MEKLEARIRNHDREIEKmcnfhyqgfvdsitellkVRGEAQKLKNQVTDTNrKLQSEGKELIIAMEELKQCRLQQRNISA 124
Cdd:PRK03918  254 KRKLEEKIRELEERIEE------------------LKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEK 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 125 TVDKLTLCLPVLEMYSKLREQMKS------KRHYPALKTLEHLEhtylPQVSHYRFCKVMVDNIPKLREEIKEVSMSDLK 198
Cdd:PRK03918  315 RLSRLEEEINGIEERIKELEEKEErleelkKKLKELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTPEKLE 390

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2024406904 199 DFLESIRKHSDKIGETAMKQAQQQRNLDNIVSQ 231
Cdd:PRK03918  391 KELEELEKAKEEIEEEISKITARIGELKKEIKE 423
 
Name Accession Description Interval E-value
Sec15 pfam04091
Exocyst complex subunit Sec15-like;
460-776 1.79e-120

Exocyst complex subunit Sec15-like;


Pssm-ID: 461169  Cd Length: 308  Bit Score: 365.70  E-value: 1.79e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 460 YKKMVGQFPFQDAELE----KQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSN 535
Cdd:pfam04091   1 YDKVLKVCWLKPDELEeapsEPTFPVTLPFSQMYPLCCIDIRNFINKFYKFSEDFYQHHREIDDILRKSLDLLLIRVVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 536 CLQNVIKrKNVGLTELVQIIINTTHLEKSCKFLEEFITNItNVLPETVHTTKLYGTTTFKDARHAAEEEIYTNLNQKIDQ 615
Cdd:pfam04091  81 SLLSRLN-STSNLSQIAQILINLEYFEIACDELEKLLAQL-RSSQNRGGTIRLTATKVFKDTRKAAEKRIFELVNSKIDD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 616 FLQLADYDWMALEPGSRASDYLVDLIGFLRSTFA-VFTHLPGDvdahstmsgkVAQTACMSACKHLSTSLMQLLLEAEVR 694
Cdd:pfam04091 159 FLELAEYDWTPTEVETEPSSYLQDLIAFLETIFSsTLTNLPES----------VKTLVYFRALDHIAESLLDLLLSPDVK 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 695 QLTLGALQQFNLDVEECEQFARSGPVPGFqGDTLQLAFIDLRQLLDLFIQWDWSTYLaDYGQPTCKYLRVNPTTALVLLE 774
Cdd:pfam04091 229 RINENAVSNFDLDVKYLESFAASLPVPGK-EESLESTFIELRQLIDLLLSDNVEEYL-DPSIRMRKYSRVKPKKAAILLE 306


                  ..
gi 2024406904 775 KI 776
Cdd:pfam04091 307 KL 308
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
45-231 1.77e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 1.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904  45 MEKLEARIRNHDREIEKmcnfhyqgfvdsitellkVRGEAQKLKNQVTDTNrKLQSEGKELIIAMEELKQCRLQQRNISA 124
Cdd:PRK03918  254 KRKLEEKIRELEERIEE------------------LKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEK 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024406904 125 TVDKLTLCLPVLEMYSKLREQMKS------KRHYPALKTLEHLEhtylPQVSHYRFCKVMVDNIPKLREEIKEVSMSDLK 198
Cdd:PRK03918  315 RLSRLEEEINGIEERIKELEEKEErleelkKKLKELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTPEKLE 390

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2024406904 199 DFLESIRKHSDKIGETAMKQAQQQRNLDNIVSQ 231
Cdd:PRK03918  391 KELEELEKAKEEIEEEISKITARIGELKKEIKE 423
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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