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Conserved domains on  [gi|1039773151|ref|XP_017176689|]
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cilia- and flagella-associated protein 99 isoform X1 [Mus musculus]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000037)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-635 8.68e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 8.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 343 QAQDLEEQLAAgecRRLQGKLSHEEAILARQNLMQENKQKADRQKEETAELMLQCAERRLQEEKAMKELVEQVTEAQKNV 422
Cdd:COG1196   214 RYRELKEELKE---LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 423 KIVQTKLVKGRQQivqevIEESRELLQRSAKEAKEEQKRRCELIAHLRAMETQ-PTRKGKLVDLTQIPGYGLEGEMSVVE 501
Cdd:COG1196   291 YELLAELARLEQD-----IARLEERRRELEERLEELEEELAELEEELEELEEElEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 502 LRERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQISLCRAAMGRTAALRWEEKKAQATSPGTPSQDERVLELKR 581
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039773151 582 KMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRLRARQEA 635
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-635 8.68e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 8.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 343 QAQDLEEQLAAgecRRLQGKLSHEEAILARQNLMQENKQKADRQKEETAELMLQCAERRLQEEKAMKELVEQVTEAQKNV 422
Cdd:COG1196   214 RYRELKEELKE---LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 423 KIVQTKLVKGRQQivqevIEESRELLQRSAKEAKEEQKRRCELIAHLRAMETQ-PTRKGKLVDLTQIPGYGLEGEMSVVE 501
Cdd:COG1196   291 YELLAELARLEQD-----IARLEERRRELEERLEELEEELAELEEELEELEEElEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 502 LRERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQISLCRAAMGRTAALRWEEKKAQATSPGTPSQDERVLELKR 581
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039773151 582 KMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRLRARQEA 635
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 312-494 4.21e-07

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 53.08  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 312 QRQVEKELQRVDKLVDGAGDFSEFLKWQ-----KKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNLMQENKQKADRQ 386
Cdd:pfam05262 180 KKVVEALREDNEKGVNFRRDMTDLKEREsqedaKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKN 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 387 KEETAELMLQCAERRLQEEKAmKELVEQVTEAQKNVKIVQtklvKGRQQIVQEVIEESRELLQRSAKEAKEEQKRRCELI 466
Cdd:pfam05262 260 LPKPADTSSPKEDKQVAENQK-REIEKAQIEIKKNDEEAL----KAKDHKAFDLKQESKASEKEAEDKELEAQKKREPVA 334

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1039773151 467 AHLRAM----ETQPTRKGKLVDLTQIPGYGLE 494
Cdd:pfam05262 335 EDLQKTkpqvEAQPTSLNEDAIDSSNPVYGLK 366
PTZ00121 PTZ00121
MAEBL; Provisional
 339-638 2.03e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 2.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  339 QKKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNLMQENKQKAD--RQKEETAELMLQCAERRLQEEKAMKELVEQVT 416
Cdd:PTZ00121  1522 KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEeaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  417 EAQKNVKIVQTKLVKGRQQIVQEV--IEESRELLQRSAKEAKEEQKRRCELiahLRAMETQPTRKgklvdltqipgygle 494
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKA--------------- 1663

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  495 gemsvvelrERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQislcRAAMGRTAALRWEEKKAQATSPGTPSQDE 574
Cdd:PTZ00121  1664 ---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA----KKAEELKKKEAEEKKKAEELKKAEEENKI 1730

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039773151  575 RVLELKRKMEE--------RAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRlraRQEANRT 638
Cdd:PTZ00121  1731 KAEEAKKEAEEdkkkaeeaKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKR---RMEVDKK 1799
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 339-638 5.13e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 5.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  339 QKKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNlmqenkqkadrQKEETAELMLQCAERRLQE-EKAMKELVEQVTE 417
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELREELEELQEELKEAE-----------EELEELTAELQELEEKLEElRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  418 AQKNVKIVQTKLVKGRQQIvqEVIEESRELLQRSAKEAKEE----QKRRCELIAHLRAMETQPTRKGKLVDltqipgygl 493
Cdd:TIGR02168  286 LQKELYALANEISRLEQQK--QILRERLANLERQLEELEAQleelESKLDELAEELAELEEKLEELKEELE--------- 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  494 egemSVVELRERLAMLKETQKREQEEKRDQIIQDKRAKSQM------IQNTVEQISLCRAAMGRTAALRWEEKKAQATSP 567
Cdd:TIGR02168  355 ----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039773151  568 GTPSQDE--RVLELKRKMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRLRARQEANRT 638
Cdd:TIGR02168  431 EEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-635 8.68e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 8.68e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 343 QAQDLEEQLAAgecRRLQGKLSHEEAILARQNLMQENKQKADRQKEETAELMLQCAERRLQEEKAMKELVEQVTEAQKNV 422
Cdd:COG1196   214 RYRELKEELKE---LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 423 KIVQTKLVKGRQQivqevIEESRELLQRSAKEAKEEQKRRCELIAHLRAMETQ-PTRKGKLVDLTQIPGYGLEGEMSVVE 501
Cdd:COG1196   291 YELLAELARLEQD-----IARLEERRRELEERLEELEEELAELEEELEELEEElEELEEELEEAEEELEEAEAELAEAEE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 502 LRERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQISLCRAAMGRTAALRWEEKKAQATSPGTPSQDERVLELKR 581
Cdd:COG1196   366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039773151 582 KMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRLRARQEA 635
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 312-494 4.21e-07

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 53.08  E-value: 4.21e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 312 QRQVEKELQRVDKLVDGAGDFSEFLKWQ-----KKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNLMQENKQKADRQ 386
Cdd:pfam05262 180 KKVVEALREDNEKGVNFRRDMTDLKEREsqedaKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKN 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 387 KEETAELMLQCAERRLQEEKAmKELVEQVTEAQKNVKIVQtklvKGRQQIVQEVIEESRELLQRSAKEAKEEQKRRCELI 466
Cdd:pfam05262 260 LPKPADTSSPKEDKQVAENQK-REIEKAQIEIKKNDEEAL----KAKDHKAFDLKQESKASEKEAEDKELEAQKKREPVA 334

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1039773151 467 AHLRAM----ETQPTRKGKLVDLTQIPGYGLE 494
Cdd:pfam05262 335 EDLQKTkpqvEAQPTSLNEDAIDSSNPVYGLK 366
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 312-579 9.20e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 9.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 312 QRQVEKELQRVDklvdgagdfSEFLKWQKKMQAQDLEEQLAAGECRRLQGKLSHEE----AILARQNLMQENKQKADRQK 387
Cdd:COG1196   262 LAELEAELEELR---------LELEELELELEEAQAEEYELLAELARLEQDIARLEerrrELEERLEELEEELAELEEEL 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 388 EETAELMLQCAERRLQEEKAMKELVEQVTEAQKNVKIVQTKLVKGRQQIVQEVIEESRELLQRSAKEAKEEQKRRcELIA 467
Cdd:COG1196   333 EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE-AEEA 411

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 468 HLRAMETQPTRKGKLVDLTQipgyglEGEMSVVELRERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQISLcRA 547
Cdd:COG1196   412 LLERLERLEEELEELEEALA------ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL-LE 484

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1039773151 548 AMGRTAALRWEEKKAQATSPGTPSQDERVLEL 579
Cdd:COG1196   485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 309-597 1.87e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 1.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 309 ALYQRQVEKELQRVDKLVDgagdfseflkwQKKMQAQDLEEQLAAGECRRLQGKLSHEEAILaRQNLMQENKQKADRQKE 388
Cdd:COG1196   231 LLKLRELEAELEELEAELE-----------ELEAELEELEAELAELEAELEELRLELEELEL-ELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 389 ETAELMLQCAERRLQEEKAMKELVEQVTEAQKNVKIVQTKLVKGRQQI-----VQEVIEESRELLQRSAKEAKEEQKRRC 463
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELeeaeeELEEAEAELAEAEEALLEAEAELAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 464 ELIAHLRAMETQPTRKgKLVDLTQIpgygLEGEMSVVELRERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQIS 543
Cdd:COG1196   379 EELEELAEELLEALRA-AAELAAQL----EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1039773151 544 LCRAAMGRTAALRWEEKKAQatspgtpSQDERVLELKRKMEERAAERRRQTAPQ 597
Cdd:COG1196   454 LEEEEEALLELLAELLEEAA-------LLEAALAELLEELAEAAARLLLLLEAE 500
PTZ00121 PTZ00121
MAEBL; Provisional
 339-638 2.03e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 2.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  339 QKKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNLMQENKQKAD--RQKEETAELMLQCAERRLQEEKAMKELVEQVT 416
Cdd:PTZ00121  1522 KKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEeaKKAEEDKNMALRKAEEAKKAEEARIEEVMKLY 1601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  417 EAQKNVKIVQTKLVKGRQQIVQEV--IEESRELLQRSAKEAKEEQKRRCELiahLRAMETQPTRKgklvdltqipgygle 494
Cdd:PTZ00121  1602 EEEKKMKAEEAKKAEEAKIKAEELkkAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKA--------------- 1663

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  495 gemsvvelrERLAMLKETQKREQEEKRDQIIQDKRAKSQMIQNTVEQislcRAAMGRTAALRWEEKKAQATSPGTPSQDE 574
Cdd:PTZ00121  1664 ---------AEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA----KKAEELKKKEAEEKKKAEELKKAEEENKI 1730

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039773151  575 RVLELKRKMEE--------RAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRlraRQEANRT 638
Cdd:PTZ00121  1731 KAEEAKKEAEEdkkkaeeaKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKR---RMEVDKK 1799
PRK11637 PRK11637
AmiB activator; Provisional
 313-480 4.23e-05

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 46.22  E-value: 4.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 313 RQVEKELQRVDKLVDGAGDFSEFLKWQKKMQAQDLEEQLAA----GECRRLQGKLSHEEA-----ILARQNLMQENKQKA 383
Cdd:PRK11637   92 RETQNTLNQLNKQIDELNASIAKLEQQQAAQERLLAAQLDAafrqGEHTGLQLILSGEESqrgerILAYFGYLNQARQET 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 384 DRQKEET-AELMLQCAE---------RRLQEEKAMKELVEQV-TEAQKNVKIVQTKLVKGRQQIVQEVIEES--RELLQR 450
Cdd:PRK11637  172 IAELKQTrEELAAQKAEleekqsqqkTLLYEQQAQQQKLEQArNERKKTLTGLESSLQKDQQQLSELRANESrlRDSIAR 251

                         170       180       190
                  ....*....|....*....|....*....|
gi 1039773151 451 SAKEAKEEQKRRCELIAHLRAMETQPTRKG 480
Cdd:PRK11637  252 AEREAKARAEREAREAARVRDKQKQAKRKG 281
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 339-638 5.13e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 5.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  339 QKKMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNlmqenkqkadrQKEETAELMLQCAERRLQE-EKAMKELVEQVTE 417
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELREELEELQEELKEAE-----------EELEELTAELQELEEKLEElRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  418 AQKNVKIVQTKLVKGRQQIvqEVIEESRELLQRSAKEAKEE----QKRRCELIAHLRAMETQPTRKGKLVDltqipgygl 493
Cdd:TIGR02168  286 LQKELYALANEISRLEQQK--QILRERLANLERQLEELEAQleelESKLDELAEELAELEEKLEELKEELE--------- 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  494 egemSVVELRERLAMLKETQKREQEEKRDQIIQDKRAKSQM------IQNTVEQISLCRAAMGRTAALRWEEKKAQATSP 567
Cdd:TIGR02168  355 ----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKL 430

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039773151  568 GTPSQDE--RVLELKRKMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQHWLELDQSRERRLRARQEANRT 638
Cdd:TIGR02168  431 EEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 369-593 2.22e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 44.66  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  369 ILARQNLMQENKQKADRQKEETAEL--MLQCAERRLQEEKAMKELVE--------QVTEAQKNVKIVQTKLVKGRQQIVQ 438
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELekALAELRKELEELEEELEQLRkeleelsrQISALRKDLARLEAEVEQLEERIAQ 751

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  439 EVIEESrELLQRSAKEAKEEQKRRCELIAHLRAMETQPTRKGKLVDLTQIPGYGLEgemsvvELRERLAMLKETQkREQE 518
Cdd:TIGR02168  752 LSKELT-ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALD------ELRAELTLLNEEA-ANLR 823

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039773151  519 EKRDQIIQDKRAKSQMIQNTVEQISLCRAAMGRTAALRWEEKKAQATSpgtPSQDERVLELKRKMEERAAERRRQ 593
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL---ESELEALLNERASLEEALALLRSE 895
PTZ00121 PTZ00121
MAEBL; Provisional
 316-637 2.67e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  316 EKELQRVDKLVDGAGDFSEFLKWQKKMQAQDLE--EQLAAGECRRLQGKLSHEEAILARQNLMQENKQKADRQKEETAEL 393
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRkfEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  394 MLQCAERRLQEEKAMKELVEQVTEAQKNVKIVQTKL--VKGRQQIVQEVIEESRELLQRSAKEAKEEQKRRCELIAHLRA 471
Cdd:PTZ00121  1303 KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAeeAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADA 1382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  472 METQPTRKGKLVDLTQipgYGLEGEMSVVELRERLAMLK--ETQKREQEEKRDQIIQDKRAKsqmiqntveqislcRAAM 549
Cdd:PTZ00121  1383 AKKKAEEKKKADEAKK---KAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAE--------------EAKK 1445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  550 GRTAALRWEEKKAQATSPGTPSQDERVLELKRKMEE-RAAERRRQTAPQLTSPPRALRpnqRAQEEMQHWLELDQSRERR 628
Cdd:PTZ00121  1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEaKKADEAKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAK 1522

                          330
                   ....*....|...
gi 1039773151  629 ----LRARQEANR 637
Cdd:PTZ00121  1523 kadeAKKAEEAKK 1535
PRK12704 PRK12704
phosphodiesterase; Provisional
 320-462 3.80e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 3.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 320 QRVDKLVDGAGDFSEFLKWQKKMQAQDLEEQL---AAGECRRLQGKLSHEEAILARQNLMQENKQKADRQKEETAELMLQ 396
Cdd:PRK12704   38 EEAKRILEEAKKEAEAIKKEALLEAKEEIHKLrneFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEK 117

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039773151 397 CAERRLQEEKAMKELVEQVTEAQKNV--KIVQTKLVKGRQQIVQEVIEESRE----LLQRSAKEAKEEQKRR 462
Cdd:PRK12704  118 ELEQKQQELEKKEEELEELIEEQLQEleRISGLTAEEAKEILLEKVEEEARHeaavLIKEIEEEAKEEADKK 189
PTZ00121 PTZ00121
MAEBL; Provisional
 339-536 1.49e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  339 QKKMQAQDL----EEQLAAGECRRLQGKLSHEEAILARQnlmQENKQKADRQKEETAELMLQCAERRLQEEKAMKELVEQ 414
Cdd:PTZ00121  1604 EKKMKAEEAkkaeEAKIKAEELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEA 1680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  415 VTEAQKNVKIVQTKLVKGRQQIVQEVIEESRELLQRSAKEAKEEQKRRCELIAHLRAMETQPTRKGKLV-----DLTQIP 489
Cdd:PTZ00121  1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAkkdeeEKKKIA 1760

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039773151  490 GYGLEGEMSVVELR-ERLAMLKETQKREQEEKR---DQIIQDKRAKSQMIQ 536
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRkEKEAVIEEELDEEDEKRRmevDKKIKDIFDNFANII 1811
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 359-465 3.13e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 39.96  E-value: 3.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 359 LQGKLSHEEAILARQNLM--QENKQKADRQKEETAElmlqcAERRLQEEKAMKElvEQVTEAQK-----NVKIVQTKLVK 431
Cdd:pfam02841 182 LQSKEAVEEAILQTDQALtaKEKAIEAERAKAEAAE-----AEQELLREKQKEE--EQMMEAQErsyqeHVKQLIEKMEA 254

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1039773151 432 GRQQIVQEVIEESRELLQRSAKEAKEEQKRRCEL 465
Cdd:pfam02841 255 EREQLLAEQERMLEHKLQEQEELLKEGFKTEAES 288
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 307-634 3.60e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 40.71  E-value: 3.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  307 EGALY--QRQVEKELQRVDKLVDGAGDFSEflkwQKKMQAQDLeeQLAAGECRRLQGKLSHEEAILARQNLMQENKQKAD 384
Cdd:COG3096    291 RRELFgaRRQLAEEQYRLVEMARELEELSA----RESDLEQDY--QAASDHLNLVQTALRQQEKIERYQEDLEELTERLE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  385 RQKEETAElmlqcaerrLQEEKAMKElvEQVTEAQKNVKIVQTKLVKgRQQIVQEviEESRELLQRSAKEAKEEQKRRCE 464
Cdd:COG3096    365 EQEEVVEE---------AAEQLAEAE--ARLEAAEEEVDSLKSQLAD-YQQALDV--QQTRAIQYQQAVQALEKARALCG 430

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  465 LiAHL---RAMETQPTRKGKLVDLTQipgyglegemSVVELRERLAMLKETqkREQEEKRDQI---IQDKRAKSQMIQNT 538
Cdd:COG3096    431 L-PDLtpeNAEDYLAAFRAKEQQATE----------EVLELEQKLSVADAA--RRQFEKAYELvckIAGEVERSQAWQTA 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  539 VEQISLCR---AAMGRTAALRWEEKKAqatspgtpsqdERVLELKRKMEERAAERRRQTAPQLTSpPRALRPNQRAQEEM 615
Cdd:COG3096    498 RELLRRYRsqqALAQRLQQLRAQLAEL-----------EQRLRQQQNAERLLEEFCQRIGQQLDA-AEELEELLAELEAQ 565

                          330       340
                   ....*....|....*....|.
gi 1039773151  616 QHWLE--LDQSRERRLRARQE 634
Cdd:COG3096    566 LEELEeqAAEAVEQRSELRQQ 586
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 261-633 5.05e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 39.95  E-value: 5.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  261 QREPQEQDVEKQLWHQSVPHIRrtpnltfykpnnlpvklntatilregalyqRQVEKELQRVDKLVDGAGDFSEFLKWQK 340
Cdd:TIGR00618  337 QSSIEEQRRLLQTLHSQEIHIR------------------------------DAHEVATSIREISCQQHTLTQHIHTLQQ 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  341 KMQAQDLEEQLAAGECRRLQGKLSHEEAILARQNLMQENKQKADRQKE---ETAELMLQCAERRLQEEKAMKELVEQVTE 417
Cdd:TIGR00618  387 QKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQElqqRYAELCAAAITCTAQCEKLEKIHLQESAQ 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  418 AQKNvkivQTKLVKGRQQIVQEVIEESRELLQRsAKEAKEEQKRRCELIAHLRAMETQ----PTRKGKLVDLTQIPGYGL 493
Cdd:TIGR00618  467 SLKE----REQQLQTKEQIHLQETRKKAVVLAR-LLELQEEPCPLCGSCIHPNPARQDidnpGPLTRRMQRGEQTYAQLE 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151  494 EGEMSV----VELRERLAMLKETQKREQEEKRDQIIQDKRAKSQM--IQNTVEQISLCRAAMGRTAALRWEEKKAQATSP 567
Cdd:TIGR00618  542 TSEEDVyhqlTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIpnLQNITVRLQDLTEKLSEAEDMLACEQHALLRKL 621

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039773151  568 GTPSQDERV-LELKRKMEERAAERRRQTAPQLTSPPRALRPNQRAQEEMQhwLELDQSRERRLRARQ 633
Cdd:TIGR00618  622 QPEQDLQDVrLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP--KELLASRQLALQKMQ 686
PRK13461 PRK13461
F0F1 ATP synthase subunit B; Provisional
 367-461 8.55e-03

F0F1 ATP synthase subunit B; Provisional


Pssm-ID: 184064 [Multi-domain]  Cd Length: 159  Bit Score: 37.34  E-value: 8.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 367 EAILARQNLMQENKQKADRQKEETAELMLQcaerRLQEEKAMKELVEQVTEAQKNvkivqtKLVKGRQQIVQEVIEESRE 446
Cdd:PRK13461   32 AVIDSRQSEIDNKIEKADEDQKKARELKLK----NERELKNAKEEGKKIVEEYKS------KAENVYEEIVKEAHEEADL 101

                          90
                  ....*....|....*
gi 1039773151 447 LLQRSAKEAKEEQKR 461
Cdd:PRK13461  102 IIERAKLEAQREKEK 116
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 339-554 8.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 8.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 339 QKKMQAQDLEEQLAAGECRRLQGKL-SHEEAILARQNLMQENKQKADRQKEETAELMLQCAERRLQEEKAMKELVEQVTE 417
Cdd:COG4942    33 QQEIAELEKELAALKKEEKALLKQLaALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRA 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039773151 418 AQKNVKIVQTKLVKGRQQIVQEVIEES--RELLQRSAKEAKEEQKRRCELIAHLRAMETQPTRKGKLVDLTQIPGYGLEG 495
Cdd:COG4942   113 LYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEA 192

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039773151 496 EMSvvelrERLAMLKETQKREQEEKRDqiIQDKRAKSQMIQNTVEQISLCRAAMGRTAA 554
Cdd:COG4942   193 LKA-----ERQKLLARLEKELAELAAE--LAELQQEAEELEALIARLEAEAAAAAERTP 244
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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