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Conserved domains on  [gi|1900314474|ref|XP_021164409|]
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RPA-interacting protein isoform X1 [Fundulus heteroclitus]

Protein Classification

RPA_interact_N and RPA_interact_C domain-containing protein( domain architecture ID 10632127)

protein containing domains RPA_interact_N, RPA_interact_M, and RPA_interact_C

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPA_interact_C pfam14768
Replication protein A interacting C-terminal; This family of proteins represents the ...
 154-235 2.34e-30

Replication protein A interacting C-terminal; This family of proteins represents the C-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The C-terminal domain is a putative zinc finger.


:

Pssm-ID: 464305  Cd Length: 80  Bit Score: 107.77  E-value: 2.34e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474 154 ICPICRMKNLSINSYFISCPCGLYINTkKRNISPDVLQRLLESRVSEHMENCLHNPVFSVTPSTESStMLMISCKACDYL 233
Cdd:pfam14768   1 ICPVCQKGNLRENSNFISCSCGLRLNT-GDSITLEHLRALLEEAVTEHSEGCSSTPQFSVEPGFGLS-SLYLSCESCDFL 78


                  ..
gi 1900314474 234 SV 235
Cdd:pfam14768  79 EV 80
RPA_interact_M pfam14767
Replication protein A interacting middle; This family of proteins represents the middle domain ...
 55-145 1.57e-19

Replication protein A interacting middle; This family of proteins represents the middle domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. This domain is responsible for interaction with RPA.


:

Pssm-ID: 434193  Cd Length: 82  Bit Score: 79.77  E-value: 1.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474  55 VQEVMEEEWSALRSEHHRLPSLWGPHGLPEvchrhiqqnrlSCQMFGVTNERDELAVLEEIQQELMSQEMSIIEEYERDL 134
Cdd:pfam14767   3 VQEVMSDELEKLKQSSTSLPSLKIPTADND-----------DMGESEDILLEMELALYEDIQQELMSQELSILEEYEESL 71

                          90
                  ....*....|.
gi 1900314474 135 QFEQQYISSVV 145
Cdd:pfam14767  72 QEEEEYLAAAV 82
RPA_interact_N pfam14766
Replication protein A interacting N-terminal; This family of proteins represents the ...
 6-44 2.65e-15

Replication protein A interacting N-terminal; This family of proteins represents the N-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The N-terminal domain is responsible for interaction with importin beta.


:

Pssm-ID: 464304  Cd Length: 39  Bit Score: 67.54  E-value: 2.65e-15
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1900314474   6 RHRSLYKGTTPPWKEAYRKRCVDRLKNSRAKLLDRYRQM 44
Cdd:pfam14766   1 PRRASYKSRSPPWKETLRERCLERLRESRQQLLWKFRSG 39
 
Name Accession Description Interval E-value
RPA_interact_C pfam14768
Replication protein A interacting C-terminal; This family of proteins represents the ...
 154-235 2.34e-30

Replication protein A interacting C-terminal; This family of proteins represents the C-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The C-terminal domain is a putative zinc finger.


Pssm-ID: 464305  Cd Length: 80  Bit Score: 107.77  E-value: 2.34e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474 154 ICPICRMKNLSINSYFISCPCGLYINTkKRNISPDVLQRLLESRVSEHMENCLHNPVFSVTPSTESStMLMISCKACDYL 233
Cdd:pfam14768   1 ICPVCQKGNLRENSNFISCSCGLRLNT-GDSITLEHLRALLEEAVTEHSEGCSSTPQFSVEPGFGLS-SLYLSCESCDFL 78


                  ..
gi 1900314474 234 SV 235
Cdd:pfam14768  79 EV 80
RPA_interact_M pfam14767
Replication protein A interacting middle; This family of proteins represents the middle domain ...
 55-145 1.57e-19

Replication protein A interacting middle; This family of proteins represents the middle domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. This domain is responsible for interaction with RPA.


Pssm-ID: 434193  Cd Length: 82  Bit Score: 79.77  E-value: 1.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474  55 VQEVMEEEWSALRSEHHRLPSLWGPHGLPEvchrhiqqnrlSCQMFGVTNERDELAVLEEIQQELMSQEMSIIEEYERDL 134
Cdd:pfam14767   3 VQEVMSDELEKLKQSSTSLPSLKIPTADND-----------DMGESEDILLEMELALYEDIQQELMSQELSILEEYEESL 71

                          90
                  ....*....|.
gi 1900314474 135 QFEQQYISSVV 145
Cdd:pfam14767  72 QEEEEYLAAAV 82
RPA_interact_N pfam14766
Replication protein A interacting N-terminal; This family of proteins represents the ...
 6-44 2.65e-15

Replication protein A interacting N-terminal; This family of proteins represents the N-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The N-terminal domain is responsible for interaction with importin beta.


Pssm-ID: 464304  Cd Length: 39  Bit Score: 67.54  E-value: 2.65e-15
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1900314474   6 RHRSLYKGTTPPWKEAYRKRCVDRLKNSRAKLLDRYRQM 44
Cdd:pfam14766   1 PRRASYKSRSPPWKETLRERCLERLRESRQQLLWKFRSG 39
 
Name Accession Description Interval E-value
RPA_interact_C pfam14768
Replication protein A interacting C-terminal; This family of proteins represents the ...
 154-235 2.34e-30

Replication protein A interacting C-terminal; This family of proteins represents the C-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The C-terminal domain is a putative zinc finger.


Pssm-ID: 464305  Cd Length: 80  Bit Score: 107.77  E-value: 2.34e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474 154 ICPICRMKNLSINSYFISCPCGLYINTkKRNISPDVLQRLLESRVSEHMENCLHNPVFSVTPSTESStMLMISCKACDYL 233
Cdd:pfam14768   1 ICPVCQKGNLRENSNFISCSCGLRLNT-GDSITLEHLRALLEEAVTEHSEGCSSTPQFSVEPGFGLS-SLYLSCESCDFL 78


                  ..
gi 1900314474 234 SV 235
Cdd:pfam14768  79 EV 80
RPA_interact_M pfam14767
Replication protein A interacting middle; This family of proteins represents the middle domain ...
 55-145 1.57e-19

Replication protein A interacting middle; This family of proteins represents the middle domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. This domain is responsible for interaction with RPA.


Pssm-ID: 434193  Cd Length: 82  Bit Score: 79.77  E-value: 1.57e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1900314474  55 VQEVMEEEWSALRSEHHRLPSLWGPHGLPEvchrhiqqnrlSCQMFGVTNERDELAVLEEIQQELMSQEMSIIEEYERDL 134
Cdd:pfam14767   3 VQEVMSDELEKLKQSSTSLPSLKIPTADND-----------DMGESEDILLEMELALYEDIQQELMSQELSILEEYEESL 71

                          90
                  ....*....|.
gi 1900314474 135 QFEQQYISSVV 145
Cdd:pfam14767  72 QEEEEYLAAAV 82
RPA_interact_N pfam14766
Replication protein A interacting N-terminal; This family of proteins represents the ...
 6-44 2.65e-15

Replication protein A interacting N-terminal; This family of proteins represents the N-terminal domain of replication protein A (RPA) interacting protein. RPA interacting protein is involved in the import of RPA into the nucleus. The N-terminal domain is responsible for interaction with importin beta.


Pssm-ID: 464304  Cd Length: 39  Bit Score: 67.54  E-value: 2.65e-15
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 1900314474   6 RHRSLYKGTTPPWKEAYRKRCVDRLKNSRAKLLDRYRQM 44
Cdd:pfam14766   1 PRRASYKSRSPPWKETLRERCLERLRESRQQLLWKFRSG 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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