NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1201899875|ref|XP_021259695|]
View 

adenylate kinase 4, mitochondrial isoform X2 [Numida meleagris]

Protein Classification

nucleoside monophosphate kinase( domain architecture ID 11995178)

nucleoside monophosphate kinase catalyzes the transfer of the terminal phosphoryl group from a nucleoside triphosphate, usually ATP, to a nucleoside monophosphate

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
10-188 9.54e-92

Adenylate kinase;


:

Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 266.87  E-value: 9.54e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEK-RRAEHWLLD 88
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQnDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  89 GFPRTLGQAEALDR----ICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDDKP 164
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 1201899875 165 EAVTARLRKYKDAAKPVIELYKSR 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
10-188 9.54e-92

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 266.87  E-value: 9.54e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEK-RRAEHWLLD 88
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQnDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  89 GFPRTLGQAEALDR----ICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDDKP 164
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 1201899875 165 EAVTARLRKYKDAAKPVIELYKSR 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-211 1.25e-91

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 267.56  E-value: 1.25e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-- 84
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 WLLDGFPRTLGQAEALDRICE--LDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDD 162
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEepIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1201899875 163 KPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGT-ETNKIWPYVYALLS 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-197 9.50e-81

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 240.03  E-value: 9.50e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQRE 160
Cdd:COG0563    82 ILDGFPRTVAQAEALDELLAelgikLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1201899875 161 DDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGT 197
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-199 1.08e-78

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 234.44  E-value: 1.08e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE----LDLVISLHIPFETLKDRLSARWIHPASGRVYNMefnpphvhGIDDVTGEPLVQRED 161
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1201899875 162 DKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
adk PRK00279
adenylate kinase; Reviewed
 6-213 8.38e-76

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 227.73  E-value: 8.38e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH- 84
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 WLLDGFPRTLGQAEALDRIC-----ELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQR 159
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1201899875 160 EDDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET-NKIWPYVYALLSNK 213
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALGKL 215
 
Name Accession Description Interval E-value
ADK pfam00406
Adenylate kinase;
10-188 9.54e-92

Adenylate kinase;


Pssm-ID: 395329 [Multi-domain]  Cd Length: 184  Bit Score: 266.87  E-value: 9.54e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEK-RRAEHWLLD 88
Cdd:pfam00406   1 LLGPPGAGKGTQAEKIVQKYGLPHLSTGDLLRAEIKSGTELGKEAKEYMDKGELVPDEVVVGLVKERLEQnDCKNGFLLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  89 GFPRTLGQAEALDR----ICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDDKP 164
Cdd:pfam00406  81 GFPRTVPQAEALEEllerGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDNE 160

                         170       180
                  ....*....|....*....|....
gi 1201899875 165 EAVTARLRKYKDAAKPVIELYKSR 188
Cdd:pfam00406 161 ETVKKRLETYHKQTKPLIDYYKKK 184
adk TIGR01351
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ...
 7-211 1.25e-91

adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 273569 [Multi-domain]  Cd Length: 210  Bit Score: 267.56  E-value: 1.25e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-- 84
Cdd:TIGR01351   1 RLVLLGPPGSGKGTQAKRIAEKYGLPHISTGDLLRAEIKAGTPLGKKAKEYMEKGELVPDEIVNQLVKERLTQNDDNEng 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 WLLDGFPRTLGQAEALDRICE--LDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDD 162
Cdd:TIGR01351  81 FILDGFPRTLSQAEALDALLEepIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQREDD 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1201899875 163 KPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGT-ETNKIWPYVYALLS 211
Cdd:TIGR01351 161 TEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNgPIDEVWKRILEALK 210
Adk COG0563
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ...
 7-197 9.50e-81

Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis


Pssm-ID: 440329 [Multi-domain]  Cd Length: 212  Bit Score: 240.03  E-value: 9.50e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:COG0563     2 RIILLGPPGAGKGTQAKRLAEKYGIPHISTGDMLRAAVKAGTELGKKAKEYMDAGELVPDEIVIGLVKERLAQPDCANgF 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQRE 160
Cdd:COG0563    82 ILDGFPRTVAQAEALDELLAelgikLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1201899875 161 DDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGT 197
Cdd:COG0563   162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGE 198
ADK cd01428
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ...
 7-199 1.08e-78

Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.


Pssm-ID: 238713 [Multi-domain]  Cd Length: 194  Bit Score: 234.44  E-value: 1.08e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:cd01428     1 RILLLGPPGSGKGTQAERLAKKYGLPHISTGDLLREEIASGTELGKKAKEYIDSGKLVPDEIVIKLLKERLKKPDCKKgF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE----LDLVISLHIPFETLKDRLSARWIHPASGRVYNMefnpphvhGIDDVTGEPLVQRED 161
Cdd:cd01428    81 ILDGFPRTVDQAEALDELLDegikPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRSD 152

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1201899875 162 DKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:cd01428   153 DNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGD 190
adk PRK00279
adenylate kinase; Reviewed
 6-213 8.38e-76

adenylate kinase; Reviewed


Pssm-ID: 234711 [Multi-domain]  Cd Length: 215  Bit Score: 227.73  E-value: 8.38e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH- 84
Cdd:PRK00279    1 MRLILLGPPGAGKGTQAKFIAEKYGIPHISTGDMLRAAVKAGTELGKEAKSYMDAGELVPDEIVIGLVKERLAQPDCKNg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 WLLDGFPRTLGQAEALDRIC-----ELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQR 159
Cdd:PRK00279   81 FLLDGFPRTIPQAEALDEMLkelgiKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1201899875 160 EDDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET-NKIWPYVYALLSNK 213
Cdd:PRK00279  161 ADDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSiDEVFADILKALGKL 215
PLN02674 PLN02674
adenylate kinase
 7-191 5.06e-54

adenylate kinase


Pssm-ID: 178279 [Multi-domain]  Cd Length: 244  Bit Score: 173.15  E-value: 5.06e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:PLN02674   33 RLILIGPPGSGKGTQSPIIKDEYCLCHLATGDMLRAAVAAKTPLGIKAKEAMDKGELVSDDLVVGIIDEAMKKPSCQKgF 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQRE 160
Cdd:PLN02674  113 ILDGFPRTVVQAQKLDEMLAkqgakIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1201899875 161 DDKPEAVTARLRKYKDAAKPVIELYKSRGIL 191
Cdd:PLN02674  193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVV 223
PRK14530 PRK14530
adenylate kinase; Provisional
 1-203 4.03e-48

adenylate kinase; Provisional


Pssm-ID: 237747 [Multi-domain]  Cd Length: 215  Bit Score: 157.26  E-value: 4.03e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   1 MASKvlRAVVLGPPGSGKGTVCERIARSFGLQHLSSGqflrESLRSGGEVGIL--------AKQYLERGLLVPDHVITRV 72
Cdd:PRK14530    1 MSQP--RILLLGAPGAGKGTQSSNLAEEFGVEHVTTG----DALRANKQMDISdmdteydtPGEYMDAGELVPDAVVNEI 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  73 MMTELEKrrAEHWLLDGFPRTLGQAEALDRICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVT 152
Cdd:PRK14530   75 VEEALSD--ADGFVLDGYPRNLEQAEYLESITDLDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDEC 152

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1201899875 153 GEPLVQREDDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET-NKIW 203
Cdd:PRK14530  153 GGELIQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTpDEVW 204
PLN02842 PLN02842
nucleotide kinase
 12-187 8.49e-40

nucleotide kinase


Pssm-ID: 178435 [Multi-domain]  Cd Length: 505  Bit Score: 142.69  E-value: 8.49e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH--WLLDG 89
Cdd:PLN02842    4 GAPASGKGTQCELIVHKFGLVHISTGDLLRAEVSAGTDIGKRAKEFMNSGRLVPDEIVIAMVTGRLSREDAKEkgWLLDG 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  90 FPRTLGQAEALDRI-CELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHvhgiDDVTGEPLVQREDDKPEAVT 168
Cdd:PLN02842   84 YPRSFAQAQSLEKLkIRPDIFILLDVPDEILIDRCVGRRLDPVTGKIYHIKNFPPE----SEEIKARLITRPDDTEEKVK 159

                         170
                  ....*....|....*....
gi 1201899875 169 ARLRKYKDAAKPVIELYKS 187
Cdd:PLN02842  160 ARLQIYKKNAEAILSTYSD 178
PRK14526 PRK14526
adenylate kinase; Provisional
 6-185 1.61e-38

adenylate kinase; Provisional


Pssm-ID: 172992 [Multi-domain]  Cd Length: 211  Bit Score: 132.67  E-value: 1.61e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVM---MTELEKRra 82
Cdd:PRK14526    1 MKLVFLGPPGSGKGTIAKILSNELNYYHISTGDLFRENILNSTPLGKEIKQIVENGQLVPDSITIKIVedkINTIKNN-- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  83 EHWLLDGFPRTLGQAEALDRICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQREDD 162
Cdd:PRK14526   79 DNFILDGFPRNINQAKALDKFLPNIKIINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDD 158

                         170       180
                  ....*....|....*....|...
gi 1201899875 163 KPEAVTARLRKYKDAAKPVIELY 185
Cdd:PRK14526  159 KEESLKTRLQEYKLQTKPLIEFY 181
PLN02459 PLN02459
probable adenylate kinase
 9-194 1.74e-36

probable adenylate kinase


Pssm-ID: 215253 [Multi-domain]  Cd Length: 261  Bit Score: 128.81  E-value: 1.74e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAE---HW 85
Cdd:PLN02459   33 VFLGCPGVGKGTYASRLSKLLGVPHIATGDLVREEIKSSGPLGAQLKEIVNQGKLVPDEIIFSLLSKRLEAGEEEgesGF 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICELDLVISLHIPFETLKDRLSARWIHPASGRVYNMEfnPPHVHGIDDVTG------------ 153
Cdd:PLN02459  113 ILDGFPRTVRQAEILEGVTDIDLVVNLKLREEVLVEKCLGRRICSECGKNFNVA--DIDLKGEDGRPGivmppllpppec 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1201899875 154 -EPLVQREDDKPEAVTARLRKYKDAAKPVIELYKSRGILHSF 194
Cdd:PLN02459  191 aSKLITRADDTEEVVKARLRVYKEESQPVEDFYRKRGKLLEF 232
adk PRK02496
adenylate kinase; Provisional
 7-199 7.33e-34

adenylate kinase; Provisional


Pssm-ID: 179433 [Multi-domain]  Cd Length: 184  Bit Score: 119.85  E-value: 7.33e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-W 85
Cdd:PRK02496    3 RLIFLGPPGAGKGTQAVVLAEHLHIPHISTGDILRQAIKEQTPLGIKAQGYMDKGELVPDQLVLDLVQERLQQPDAANgW 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARwihpasgrvynmefnpphvhgiddvtgeplvQRE 160
Cdd:PRK02496   83 ILDGFPRKVTQAAFLDELLQeigqsGERVVNLDVPDDVVVERLLAR-------------------------------GRK 131

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1201899875 161 DDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:PRK02496  132 DDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQS 170
aden_kin_iso1 TIGR01360
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ...
 10-192 2.83e-33

adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.


Pssm-ID: 130427 [Multi-domain]  Cd Length: 188  Bit Score: 118.38  E-value: 2.83e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRV----MMTELEKRRAehW 85
Cdd:TIGR01360   8 IVGGPGSGKGTQCEKIVEKYGFTHLSTGDLLRAEVASGSERGKQLQAIMESGDLVPLDTVLDLlkdaMVAALGTSKG--F 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALD-RICELDLVISLHIPFETLKDRLSARwiHPASGRVynmefnpphvhgiddvtgeplvqreDDKP 164
Cdd:TIGR01360  86 LIDGYPREVKQGEEFErRIGPPTLVLYFDCSEDTMVKRLLKR--AETSGRV-------------------------DDNE 138

                         170       180
                  ....*....|....*....|....*...
gi 1201899875 165 EAVTARLRKYKDAAKPVIELYKSRGILH 192
Cdd:TIGR01360 139 KTIKKRLETYYKATEPVIAYYETKGKLR 166
PRK14527 PRK14527
adenylate kinase; Provisional
 9-199 5.90e-33

adenylate kinase; Provisional


Pssm-ID: 237745 [Multi-domain]  Cd Length: 191  Bit Score: 117.58  E-value: 5.90e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEHWLLD 88
Cdd:PRK14527   10 IFLGPPGAGKGTQAERLAQELGLKKLSTGDILRDHVARGTELGQRAKPIMEAGDLVPDELILALIRDELAGMEPVRVIFD 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  89 GFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARwihpasGRvynmefnpphvhgiddvtgepLVQREDDK 163
Cdd:PRK14527   90 GFPRTLAQAEALDRLLEelgarLLAVVLLEVPDEELIRRIVER------AR---------------------QEGRSDDN 142

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1201899875 164 PEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:PRK14527  143 EETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGT 178
PRK14531 PRK14531
adenylate kinase; Provisional
 7-193 2.46e-31

adenylate kinase; Provisional


Pssm-ID: 172997 [Multi-domain]  Cd Length: 183  Bit Score: 112.98  E-value: 2.46e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEHWL 86
Cdd:PRK14531    4 RLLFLGPPGAGKGTQAARLCAAHGLRHLSTGDLLRSEVAAGSALGQEAEAVMNRGELVSDALVLAIVESQLKALNSGGWL 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  87 LDGFPRTLGQAEALDricelDLVISLHIPFETlkdrlsarwihpasgrVYNMEFNpphvhgiDDVTGEPLVQ--REDDKP 164
Cdd:PRK14531   84 LDGFPRTVAQAEALE-----PLLEELKQPIEA----------------VVLLELD-------DAVLIERLLArgRADDNE 135

                         170       180
                  ....*....|....*....|....*....
gi 1201899875 165 EAVTARLRKYKDAAKPVIELYKSRGILHS 193
Cdd:PRK14531  136 AVIRNRLEVYREKTAPLIDHYRQRGLLQS 164
PRK14528 PRK14528
adenylate kinase; Provisional
 7-199 2.55e-31

adenylate kinase; Provisional


Pssm-ID: 172994 [Multi-domain]  Cd Length: 186  Bit Score: 113.18  E-value: 2.55e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   7 RAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTEL-EKRRAEHW 85
Cdd:PRK14528    3 NIIFMGPPGAGKGTQAKILCERLSIPQISTGDILREAVKNQTAMGIEAKRYMDAGDLVPDSVVIGIIKDRIrEADCKNGF 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  86 LLDGFPRTLGQAEALDRIC-----ELDLVISLHIPFETLKDRLSARWIHPAsgrvynmefnpphvhgiddvtgeplvqRE 160
Cdd:PRK14528   83 LLDGFPRTVEQADALDALLknegkSIDKAINLEVPDGELLKRLLGRAEIEG---------------------------RA 135

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1201899875 161 DDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:PRK14528  136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGS 174
PRK13808 PRK13808
adenylate kinase; Provisional
 6-196 2.84e-31

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 116.91  E-value: 2.84e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH- 84
Cdd:PRK13808    1 MRLILLGPPGAGKGTQAQRLVQQYGIVQLSTGDMLRAAVAAGTPVGLKAKDIMASGGLVPDEVVVGIISDRIEQPDAANg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 WLLDGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSArwihpasgRVYNMEfnpphvhgiddVTGEPLvqR 159
Cdd:PRK13808   81 FILDGFPRTVPQAEALDALLKdkqlkLDAVVELRVNEGALLARVET--------RVAEMR-----------ARGEEV--R 139

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1201899875 160 EDDKPEAVTARLRKYKDAAKPVIELYKSRGILHSFSG 196
Cdd:PRK13808  140 ADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDG 176
PTZ00088 PTZ00088
adenylate kinase 1; Provisional
 6-190 8.52e-31

adenylate kinase 1; Provisional


Pssm-ID: 240262 [Multi-domain]  Cd Length: 229  Bit Score: 112.97  E-value: 8.52e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH- 84
Cdd:PTZ00088    7 LKIVLFGAPGVGKGTFAEILSKKENLKHINMGNILREEIKAKTTIGKEIQKVVTSGNLVPDNLVIAIVKDEIAKVTDDCf 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  85 --WLLDGFPRTLGQAEALDRICELDLVISLHIPFETLKDRLSARWIHPASGRVYNM------EFNPPHV---HGIDDVTG 153
Cdd:PTZ00088   87 kgFILDGFPRNLKQCKELGKITNIDLFVNIYLPRNILIKKLLGRRICNTCNRNFNIahirsdPYDMPPIlppADCEGCKG 166

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1201899875 154 EP-LVQREDDKPEAVTARLRKYKDAAKPVIELYKSRGI 190
Cdd:PTZ00088  167 NPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
UMP_CMP_kin_fam TIGR01359
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ...
 10-211 9.46e-28

UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.


Pssm-ID: 273576 [Multi-domain]  Cd Length: 185  Bit Score: 103.99  E-value: 9.46e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESL-RSGGEVGILAKQYLERGLLVPDHVITRVMMTEL-EKRRAEHWLL 87
Cdd:TIGR01359   4 VLGGPGSGKGTQCAKIVENFGFTHLSAGDLLRAEIkREGSENGSLIESYIKEGKIVPSEVTVELLKKAIqEDGSSKKFLI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  88 DGFPRTLGQAEA----LDRICELDLVISLHIPFETLKDRLSARwiHPASGRVynmefnpphvhgiddvtgeplvqreDDK 163
Cdd:TIGR01359  84 DGFPRNEENLEAweklMDNKVNFKFVLFFDCPEETMIKRLLKR--GQTSGRV-------------------------DDN 136

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1201899875 164 PEAVTARLRKYKDAAKPVIELYKSRGILHSFSGTET-NKIWPYVYALLS 211
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSvEEVFEDVEKIFA 185
PRK14532 PRK14532
adenylate kinase; Provisional
 9-196 3.15e-27

adenylate kinase; Provisional


Pssm-ID: 184729 [Multi-domain]  Cd Length: 188  Bit Score: 102.59  E-value: 3.15e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTEL-EKRRAEHWLL 87
Cdd:PRK14532    4 ILFGPPAAGKGTQAKRLVEERGMVQLSTGDMLRAAIASGSELGQRVKGIMDRGELVSDEIVIALIEERLpEAEAAGGAIF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  88 DGFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARWIHPAsgrvynmefnpphvhgiddvtgeplvqREDD 162
Cdd:PRK14532   84 DGFPRTVAQAEALDKMLAsrgqkIDVVIRLKVDDEALIERIVKRFEEQG---------------------------RPDD 136

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1201899875 163 KPEAVTARLRKYKDAAKPVIELYKSRGILHSFSG 196
Cdd:PRK14532  137 NPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDG 170
PRK14529 PRK14529
adenylate kinase; Provisional
 9-176 4.91e-27

adenylate kinase; Provisional


Pssm-ID: 237746 [Multi-domain]  Cd Length: 223  Bit Score: 102.88  E-value: 4.91e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEHWLLD 88
Cdd:PRK14529    4 LIFGPNGSGKGTQGALVKKKYDLAHIESGAIFREHIGGGTELGKKAKEYIDRGDLVPDDITIPMILETLKQDGKNGWLLD 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  89 GFPRTLGQAEALDRICE-----LDLVISLHIPFETLKDRLSARwihpasgRVYNMEFNPPHVHGIDD---------VTGE 154
Cdd:PRK14529   84 GFPRNKVQAEKLWEALQkegmkLDYVIEILLPREVAKNRIMGR-------RLCKNDNNHPNNIFIDAikpdgdvcrVCGG 156

                         170       180
                  ....*....|....*....|...
gi 1201899875 155 PLVQREDDKPE-AVTARLRKYKD 176
Cdd:PRK14529  157 ELSTRADDQDEeAINKRHDIYYD 179
PLN02200 PLN02200
adenylate kinase family protein
 10-199 4.20e-26

adenylate kinase family protein


Pssm-ID: 215125 [Multi-domain]  Cd Length: 234  Bit Score: 101.12  E-value: 4.20e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  10 VLGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITRVMMTELEKRRAEHWLLDG 89
Cdd:PLN02200   48 VLGGPGSGKGTQCEKIVETFGFKHLSAGDLLRREIASNSEHGAMILNTIKEGKIVPSEVTVKLIQKEMESSDNNKFLIDG 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  90 FPRTLGQAEALDRI--CELDLVISLHIPFETLKDRLSARwihpASGRVynmefnpphvhgiddvtgeplvqreDDKPEAV 167
Cdd:PLN02200  128 FPRTEENRIAFERIigAEPNVVLFFDCPEEEMVKRVLNR----NQGRV-------------------------DDNIDTI 178

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1201899875 168 TARLRKYKDAAKPVIELYKSRGILHSFSGTET 199
Cdd:PLN02200  179 KKRLKVFNALNLPVIDYYSKKGKLYTINAVGT 210
AAA_17 pfam13207
AAA domain;
11-123 6.16e-25

AAA domain;


Pssm-ID: 463810 [Multi-domain]  Cd Length: 136  Bit Score: 95.00  E-value: 6.16e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  11 LGPPGSGKGTVCERIARSFGLQHLSSGQFLRESLRSGGevGILAKQYLERGLLVPDHVITRVMMTELEKRRAEH-WLLDG 89
Cdd:pfam13207   1 TGVPGSGKTTQLKKLAEKLGFPHISAGDLLREEAKERG--LVEDRDEMRKLPLEPQKELQKLAAERIAEEAGEGgVIVDG 78

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1201899875  90 FPRTLGQAEALD-------RICELDLVISLHIPFETLKDRL 123
Cdd:pfam13207  79 HPRIKTPAGYLPglpvevlRELKPDAIILLEADPEEILERR 119
ADK_lid pfam05191
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ...
 126-161 6.26e-17

Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.


Pssm-ID: 461578 [Multi-domain]  Cd Length: 36  Bit Score: 71.34  E-value: 6.26e-17
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1201899875 126 RWIHPASGRVYNMEFNPPHVHGIDDVTGEPLVQRED 161
Cdd:pfam05191   1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 12-54 7.04e-07

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.10  E-value: 7.04e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSGqFLRESlrsggEVGILA 54
Cdd:cd02020     6 GPAGSGKSTVAKLLAKKLGLPYLDTG-GIRTE-----EVGKLA 42
PRK04182 PRK04182
cytidylate kinase; Provisional
 6-62 1.97e-06

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 46.34  E-value: 1.97e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1201899875   6 LRAVVLGPPGSGKGTVCERIARSFGLQHLSSGQFLREslrsggevgiLAKqylERGL 62
Cdd:PRK04182    1 MIITISGPPGSGKTTVARLLAEKLGLKHVSAGEIFRE----------LAK---ERGM 44
AAA_18 pfam13238
AAA domain;
9-126 4.61e-06

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 44.73  E-value: 4.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARsfglqHLSSGQFLRESLRSGGEVgILAKQYLERGLLVPDHVITRVmMTELEK----RRAEH 84
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSK-----RLGFGDNVRDLALENGLV-LGDDPETRESKRLDEDKLDRL-LDLLEEnaalEEGGN 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1201899875  85 WLLDGFPRTLGQAEALDRiceldLVISLHIPFETLKDRLSAR 126
Cdd:pfam13238  75 LIIDGHLAELEPERAKDL-----VGIVLRASPEELLERLEKR 111
cyt_kin_arch TIGR02173
cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. ...
 9-42 1.05e-05

cytidylate kinase, putative; Proteins in this family are believed to be cytidylate kinase. Members of this family are found in the archaea and in spirochaetes, and differ considerably from the common bacterial form of cytidylate kinase described by TIGR00017.


Pssm-ID: 274012 [Multi-domain]  Cd Length: 171  Bit Score: 44.34  E-value: 1.05e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSSGQFLRE 42
Cdd:TIGR02173   4 TISGPPGSGKTTVAKILAEKLSLKLISAGDIFRE 37
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 12-41 6.68e-05

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 42.29  E-value: 6.68e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSGQFLR 41
Cdd:pfam02224   5 GPSGSGKSTVARILARKLGYKYLDTGAMYR 34
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
12-37 2.16e-04

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 40.78  E-value: 2.16e-04
                          10        20
                  ....*....|....*....|....*.
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSG 37
Cdd:COG0283     7 GPAGSGKSTVAKALAKRLGYHYLDTG 32
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
12-47 1.30e-03

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 39.26  E-value: 1.30e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSGQFLR----ESLRSG 47
Cdd:PRK11860  449 GPTASGKGTVAARVAEALGYHYLDSGALYRltalAALRAG 488
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 9-129 1.63e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 37.62  E-value: 1.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHL--------------SSGQFLRESLRSGGEVGILAKQYLERGLLVPDHVITrvmm 74
Cdd:cd02021     3 VVMGVSGSGKSTVGKALAERLGAPFIdgddlhppaniakmAAGIPLNDEDRWPWLQALTDALLAKLASAGEGVVVA---- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1201899875  75 TELEKRRAEHWLLDGFPrtlgqaealdricELDLVIS-LHIPFETLKDRLSARWIH 129
Cdd:cd02021    79 CSALKRIYRDILRGGAA-------------NPRVRFVhLDGPREVLAERLAARKGH 121
cmk TIGR00017
cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the ...
 12-41 1.97e-03

cytidylate kinase; This family consists of cytidylate kinase, which catalyzes the phosphorylation of cytidine 5-monophosphate (dCMP) to cytidine 5 -diphosphate (dCDP) in the presence of ATP or GTP. UMP and dCMP can also act as acceptors. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]


Pssm-ID: 129128 [Multi-domain]  Cd Length: 217  Bit Score: 38.18  E-value: 1.97e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLSSGQFLR 41
Cdd:TIGR00017   9 GPSGAGKSTVAKAVAEKLGYAYLDSGAMYR 38
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
9-126 2.29e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 37.59  E-value: 2.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCERIARSFGLQHLSS---------------GQFLRESLRSGGEVGILAKQYLERGLLVpdhVITRVM 73
Cdd:COG0645     3 LVCGLPGSGKSTLARALAERLGAVRLRSdvvrkrlfgaglaplERSPEATARTYARLLALARELLAAGRSV---ILDATF 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1201899875  74 MTELEKRRAEHWlldgfprtlgqAEALDriCELdLVISLHIPFETLKDRLSAR 126
Cdd:COG0645    80 LRRAQREAFRAL-----------AEEAG--APF-VLIWLDAPEEVLRERLEAR 118
PRK01184 PRK01184
flagellar hook-basal body complex protein FliE;
9-126 6.16e-03

flagellar hook-basal body complex protein FliE;


Pssm-ID: 234914 [Multi-domain]  Cd Length: 184  Bit Score: 36.46  E-value: 6.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875   9 VVLGPPGSGKGTVCeRIARSFGLQHLSSGQFLRESLRSGG------EVGILAKQylERGLLVPDhVITRVMMTELEKRRA 82
Cdd:PRK01184    5 GVVGMPGSGKGEFS-KIAREMGIPVVVMGDVIREEVKKRGleptdeNIGKVAID--LRKELGMD-AVAKRTVPKIREKGD 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1201899875  83 EHWLLDGFpRTLGQAEALDRICELDL-VISLHIPFETLKDRLSAR 126
Cdd:PRK01184   81 EVVVIDGV-RGDAEVEYFRKEFPEDFiLIAIHAPPEVRFERLKKR 124
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
12-94 7.49e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 35.96  E-value: 7.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1201899875  12 GPPGSGKGTVCERIARSFGLQHLsSGQFLRESLRSGGEVGILAKQYLER--GLLVPDHVITRVMMTELEKR--------- 80
Cdd:COG1102     7 REPGSGGTTIAKRLAEKLGLPLY-DGEILREAAKERGLSEEEFEKLDEKapSLLYRDTAEEDEIDRALDKVirelarkgn 85

                          90
                  ....*....|....*....
gi 1201899875  81 -----RAEHWLLDGFPRTL 94
Cdd:COG1102    86 cvivgRLADWILRDRPNVL 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH