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Conserved domains on  [gi|1387272084|ref|XP_024848870|]
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alpha-adducin isoform X3 [Bos taurus]

Protein Classification

class II aldolase/adducin head domain-containing protein( domain architecture ID 842)

class II aldolase/adducin head domain-containing protein involved in catalyzing central steps of carbohydrate metabolism; it promotes carbon-carbon bond cleavage and stabilizes enolate intermediates using divalent cations

Gene Symbol:  ADD3
PubMed:  10581174

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Aldolase_II super family cl00214
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 145-391 2.94e-98

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


The actual alignment was detected with superfamily member PRK07044:

Pssm-ID: 469663  Cd Length: 252  Bit Score: 303.69  E-value: 2.94e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 225 SAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKILIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLDPGKYKAKSRAPGSPAGEGSgsppkwqiGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAGA--------GELAWPALLRK 242

                         250
                  ....*....|
gi 1387272084 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 145-391 2.94e-98

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 303.69  E-value: 2.94e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 225 SAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKILIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLDPGKYKAKSRAPGSPAGEGSgsppkwqiGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAGA--------GELAWPALLRK 242

                         250
                  ....*....|
gi 1387272084 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 142-352 8.13e-69

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 224.94  E-value: 8.13e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 142 EKLLRcKLAAFYRLADLFGWSQLIYNHITTRvSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIV--DRGSTNLGvnqa 219
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVegKKPSSETP---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 220 gftLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL---GEVAYHDYHGILvDEEEKILIQKNLG-PKSK 295
Cdd:cd00398    75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfPNSK 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1387272084 296 VLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGG--PDNLVLLDPGKYKAK 352
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQlpPISLELLNKEYLRKH 209
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 145-341 2.00e-57

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 194.28  E-value: 2.00e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVssEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGstnlGVNQAGFTLH 224
Cdd:COG0235     6 LREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 225 SAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPIS-PEAL-SLGEVAYHDYHGIlVDEEEKILIQKNLGpKSKVLILRNH 302
Cdd:COG0235    80 LAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEqTEAAaFLGDVPVVPYAGP-GTEELAEAIAEALG-DRPAVLLRNH 157

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1387272084 303 GLVSVGESVEEAFYYIHNLVVACEIQVRTLAsAGGPDNL 341
Cdd:COG0235   158 GVVVWGKDLAEAFDRAEVLEEAARIQLLALA-LGGPLVL 195
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 147-329 1.10e-55

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 188.52  E-value: 1.10e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 147 CKLAAFYRLADLFGWSQLIYNHITTRVssEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGstnLGVNqAGFTLHSA 226
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG---LKPS-SETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 227 IYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGiLVDEEEKILIQKNLGPKSKVLILRNHGL 304
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYT-PGTEELGERIAEALGGDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1387272084 305 VSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 149-329 1.12e-53

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 183.22  E-value: 1.12e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084  149 LAAFYRLADLFGWSQLIYNHITTRVSsEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGSTnlGVNQAGFTLHSAIY 228
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084  229 AARPDVRCVVHIHTPAGAAVSAM--KCGLLPIS-PEALSLGEVAYHDYHGILVDEEEKI-LIQKNLGPK---SKVLILRN 301
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEqAAAFLGGEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1387272084  302 HGLVSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
 
Name Accession Description Interval E-value
PRK07044 PRK07044
aldolase II superfamily protein; Provisional
 145-391 2.94e-98

aldolase II superfamily protein; Provisional


Pssm-ID: 235916  Cd Length: 252  Bit Score: 303.69  E-value: 2.94e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrgSTNLGVNQAGFTLH 224
Cdd:PRK07044   17 ARVDLAAAYRLVALLGWDDLIYTHISARVPGEEHHFLINPYGLLFDEITASNLVKIDLDGNVVD--DSPYPVNPAGFTIH 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 225 SAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAYHDYHGILVDEEEKILIQKNLGPKsKVLILRNHG 303
Cdd:PRK07044   95 SAIHAARPDAHCVMHTHTTAGVAVSAQRDGLLPLSQHALQFyGRLAYHDYEGIALDLDEGERLVADLGDK-PAMLLRNHG 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 304 LVSVGESVEEAFYYIHNLVVACEIQVRTLaSAGGPdnLVLLDPGKYKAKSRAPGSPAGEGSgsppkwqiGEQEFEALMRM 383
Cdd:PRK07044  174 LLTVGRTVAEAFLLMYTLERACEIQVAAQ-AGGGE--LVLPPPEVAERTARQSLFDPGAGA--------GELAWPALLRK 242

                         250
                  ....*....|
gi 1387272084 384 LD--NLGYRT 391
Cdd:PRK07044  243 LDriDPGYRD 252
Aldolase_II cd00398
Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes ...
 142-352 8.13e-69

Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). Class II enzymes are further divided into two sub-classes A and B. This family includes class II A aldolases and adducins which has not been ascribed any enzymatic function. Members of this class are primarily bacterial and eukaryotic in origin and include L-fuculose-1-phosphate, L-rhamnulose-1-phosphate aldolases and L-ribulose-5-phosphate 4-epimerases. They all share the ability to promote carbon-carbon bond cleavage and stabilize enolate intermediates using divalent cations.


Pssm-ID: 238232 [Multi-domain]  Cd Length: 209  Bit Score: 224.94  E-value: 8.13e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 142 EKLLRcKLAAFYRLADLFGWSQLIYNHITTRvSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIV--DRGSTNLGvnqa 219
Cdd:cd00398     1 EKLKR-KIIAACLLLDLYGWVTGTGGNVSAR-DRDRGYFLITPSGVDYEEMTASDLVVVDAQGKVVegKKPSSETP---- 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 220 gftLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL---GEVAYHDYHGILvDEEEKILIQKNLG-PKSK 295
Cdd:cd00398    75 ---LHLALYRARPDIGCIVHTHSTHATAVSQLKEGLIPAGHTACAVyftGDIPCTPYMTPE-TGEDEIGTQRALGfPNSK 150

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1387272084 296 VLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGG--PDNLVLLDPGKYKAK 352
Cdd:cd00398   151 AVLLRNHGLFAWGPTLDEAFHLAVVLEVAAEIQLKALSMGGQlpPISLELLNKEYLRKH 209
AraD COG0235
5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar ...
 145-341 2.00e-57

5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) [Amino acid transport and metabolism, Carbohydrate transport and metabolism]; 5-methylthioribulose/5-deoxyribulose/Fuculose 1-phosphate aldolase (methionine salvage, sugar degradation) is part of the Pathway/BioSystem: Urea cycle


Pssm-ID: 440005 [Multi-domain]  Cd Length: 208  Bit Score: 194.28  E-value: 2.00e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRVssEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGstnlGVNQAGFTLH 224
Cdd:COG0235     6 LREELAAAGRRLARRGLVDGTAGNISVRL--DDDRFLITPSGVDFGELTPEDLVVVDLDGNVVEGD----LKPSSETPLH 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 225 SAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPIS-PEAL-SLGEVAYHDYHGIlVDEEEKILIQKNLGpKSKVLILRNH 302
Cdd:COG0235    80 LAIYRARPDVGAVVHTHSPYATALSALGEPLPPLEqTEAAaFLGDVPVVPYAGP-GTEELAEAIAEALG-DRPAVLLRNH 157

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1387272084 303 GLVSVGESVEEAFYYIHNLVVACEIQVRTLAsAGGPDNL 341
Cdd:COG0235   158 GVVVWGKDLAEAFDRAEVLEEAARIQLLALA-LGGPLVL 195
Aldolase_II pfam00596
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 147-329 1.10e-55

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 459862 [Multi-domain]  Cd Length: 178  Bit Score: 188.52  E-value: 1.10e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 147 CKLAAFYRLADLFGWSQLIYNHITTRVssEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGstnLGVNqAGFTLHSA 226
Cdd:pfam00596   1 EELAAAGRLLARRGLVEGTGGNISVRL--PGDGFLITPSGVDFGELTPEDLVVVDLDGNVVEGG---LKPS-SETPLHLA 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 227 IYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL--GEVAYHDYHGiLVDEEEKILIQKNLGPKSKVLILRNHGL 304
Cdd:pfam00596  75 IYRARPDAGAVVHTHSPYATALSLAKEGLPPITQEAADFlgGDIPIIPYYT-PGTEELGERIAEALGGDRKAVLLRNHGL 153

                         170       180
                  ....*....|....*....|....*
gi 1387272084 305 VSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:pfam00596 154 LVWGKTLEEAFYLAEELERAAEIQL 178
Aldolase_II smart01007
Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and ...
 149-329 1.12e-53

Class II Aldolase and Adducin N-terminal domain; This family includes class II aldolases and adducins which have not been ascribed any enzymatic function.


Pssm-ID: 214970 [Multi-domain]  Cd Length: 185  Bit Score: 183.22  E-value: 1.12e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084  149 LAAFYRLADLFGWSQLIYNHITTRVSsEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDRGSTnlGVNQAGFTLHSAIY 228
Cdd:smart01007   1 LAAACRLLARRGLVEGTGGNISARVG-EEDLFLITPSGVDFGELTASDLVVVDLDGNVVEGGGG--PKPSSETPLHLAIY 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084  229 AARPDVRCVVHIHTPAGAAVSAM--KCGLLPIS-PEALSLGEVAYHDYHGILVDEEEKI-LIQKNLGPK---SKVLILRN 301
Cdd:smart01007  78 RARPDVGAVVHTHSPYATALAALgkPLPLLPTEqAAAFLGGEIPYAPYAGPGTELAEEGaELAEALAEAlpdRPAVLLRN 157

                          170       180
                   ....*....|....*....|....*...
gi 1387272084  302 HGLVSVGESVEEAFYYIHNLVVACEIQV 329
Cdd:smart01007 158 HGLLVWGKTLEEAFDLAEELEEAAEIQL 185
PRK06661 PRK06661
hypothetical protein; Provisional
 149-334 2.01e-44

hypothetical protein; Provisional


Pssm-ID: 168637  Cd Length: 231  Bit Score: 159.61  E-value: 2.01e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 149 LAAFYRLADLFGWSQLIYNHITTRvSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrgSTNLGVNQAGFTLHSAIY 228
Cdd:PRK06661    7 LAAAYRIMAYLSLDDHTYTHLSAR-PKNADFYYIYPFGLRFEEVTTENLLKVSLDGQILE--GEEYQYNKTGYFIHGSIY 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 229 AARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSLGE-VAYHDYHGILVDE--EEKILIQkNLGpKSKVLILRNHGLV 305
Cdd:PRK06661   84 KTRPDISAIFHYHTPASIAVSALKCGLLPISQWALHFYDrISYHNYNSLALDAdkQSSRLVN-DLK-QNYVMLLRNHGAI 161

                         170       180
                  ....*....|....*....|....*....
gi 1387272084 306 SVGESVEEAFYYIHNLVVACEIQVRTLAS 334
Cdd:PRK06661  162 TCGKTIHEAMFYTYHLEQACKTQCLLNST 190
PRK06208 PRK06208
class II aldolase/adducin family protein;
148-371 3.68e-42

class II aldolase/adducin family protein;


Pssm-ID: 235743  Cd Length: 274  Bit Score: 154.38  E-value: 3.68e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 148 KLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrgsTNLGVNQAGFTLHSAI 227
Cdd:PRK06208   46 RLAAAFRLFARFGFDEGLAGHITARDPELPDHFWVNPLGVHFSQIKVSDLLLVDHDGEVVE---GDRPLNRAAFAIHSAI 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 228 YAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSLGE--VAYHDYHGILVDEEEKILIQKNLGPKsKVLILRNHGLV 305
Cdd:PRK06208  123 HEARPDVVAAAHTHSTYGKAWSTLGRPLDPITQDACAFYEdhALFDDFTGVVVDTSEGRRIAAALGTH-KAVILQNHGLL 201

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1387272084 306 SVGESVEEA-FYYIhNLVVACEIQVrtLASAGGPdnLVLLDPGKYKAKSRAPGSPAGEGSGSPPKWQ 371
Cdd:PRK06208  202 TVGPSVDAAaWWFI-ALERACQTQL--LAEAAGP--PQPIDHETARHTRSQVGSEYGGWFNFQPLYQ 263
PRK06486 PRK06486
aldolase;
114-385 7.98e-27

aldolase;


Pssm-ID: 235814  Cd Length: 262  Bit Score: 110.19  E-value: 7.98e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 114 MA-ALNMSLGMVTPVNDLRGSDSIAYdkgeklLRCKLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEV 192
Cdd:PRK06486    1 MAhSLTTDSAPPAGNRPLLDSDAVAQ------ARVDLAACFRAAARHGLEEGICNHFSAVLPGHDDLFLVNPYGYAFSEI 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 193 TASSLVKVNLQGDIVD-RGStnlgVNQAGFTLHSAIYAARPDVRCVVHIHTPAGAAVSAMK-CGLLPISPEALSL-GEVA 269
Cdd:PRK06486   75 TASDLLICDFDGNVLAgRGE----PEATAFFIHARIHRAIPRAKAAFHTHMPYATALSLTEgRPLTTLGQTALKFyGRTA 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 270 Y-HDYHGILVDEEEKILIQKNLGPKSkVLILRNHGLVSVGESVEEAF---YYihnLVVACEIQVRTLaSAGGPdnLVLLD 345
Cdd:PRK06486  151 VdEDYNGLALDAAEGDRIARAMGDAD-IVFLKNHGVMVCGPRIAEAWddlYY---LERACEVQVLAM-STGRP--LVPVD 223

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1387272084 346 PGKYKAKSRapgspagegsgsppKWQIGEQE-----FEALMRMLD 385
Cdd:PRK06486  224 PAIAAAVAR--------------QMREGDREsarlhLEALRRTLD 254
PRK07490 PRK07490
hypothetical protein; Provisional
 135-334 1.32e-20

hypothetical protein; Provisional


Pssm-ID: 236031 [Multi-domain]  Cd Length: 245  Bit Score: 91.70  E-value: 1.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 135 SIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVSSEQEHFLIVPFGLLYSEVTASSLVKVNlqGDIVDRGSTNL 214
Cdd:PRK07490    1 MTMALSDEEQIRVDLAAAFRWIARLGMHEAVANHFSAAVSADGKQFLLNPKWKHFSRIRASDLLLLD--ADDPSTAERPD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 215 GVNQAGFTLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCG-LLPISPE-ALSLGEVAYHDYHGILVDEEEKILIQKNLGP 292
Cdd:PRK07490   79 VPDATAWAIHGQIHRRLPHARCVMHVHSVYATALACLADPtLPPIDQNtARFFNRVAVDTLYGGMALEEEGERLAGLLGD 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1387272084 293 KSkVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLAS 334
Cdd:PRK07490  159 KR-RLLMGNHGVLVTGDTVAEAFDDLYYFERACQTYITALST 199
PRK07090 PRK07090
class II aldolase/adducin domain protein; Provisional
 145-338 1.11e-19

class II aldolase/adducin domain protein; Provisional


Pssm-ID: 180832  Cd Length: 260  Bit Score: 89.31  E-value: 1.11e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 145 LRCKLAAFYRLADLFGWSQLIYNHITTRvSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVD-RGSTNlGVNQagftL 223
Cdd:PRK07090   31 LRQKLALTCRILFDAGHDSGLAGQITAR-AEAPGTYYTQRLGLGFDEITASNLLLVDEDLNVLDgEGMPN-PANR----F 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 224 HSAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLPISPEALSL-GEVAY-HDYHGILVDEEEKILIQKNLGPKSKVLiLRN 301
Cdd:PRK07090  105 HSWIYRARPDVNCIIHTHPPHVAALSMLEVPLVVSHMDTCPLyDDCAFlKDWPGVPVGNEEGEIISAALGDKRAIL-LSH 183

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1387272084 302 HGLVSVGESVEEAFYYIHNLVVACEIQVrtLASAGGP 338
Cdd:PRK07090  184 HGQLVAGKSIEEACVLALLIERAARLQL--LAMAAGP 218
PRK08333 PRK08333
aldolase;
143-316 1.09e-12

aldolase;


Pssm-ID: 181393 [Multi-domain]  Cd Length: 184  Bit Score: 67.16  E-value: 1.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 143 KLLRCKLAAFYRLADLFGWSQLIYNHITTRVSseqEHFLIVPFGLLYSEVTASSLVKVNLQGDIVD--RGSTNlgvnqag 220
Cdd:PRK08333    2 RNVKAQLVKYSKLAHERGLTAAFGGNLSIRVG---NLVFIKATGSVMDELTREQVAVIDLNGNQLSsvRPSSE------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 221 FTLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCGLLP-ISPEA-LSLGEVAYHDYHGI----LVDEEEKILIQKNlgpks 294
Cdd:PRK08333   72 YRLHLAVYRNRPDVRAIAHLHPPYSIVASTLLEEELPiITPEAeLYLKKIPILPFRPAgsveLAEQVAEAMKEYD----- 146

                         170       180
                  ....*....|....*....|..
gi 1387272084 295 kVLILRNHGLVSVGESVEEAFY 316
Cdd:PRK08333  147 -AVIMERHGIVTVGRSLREAFY 167
PRK06557 PRK06557
L-ribulose-5-phosphate 4-epimerase; Validated
 176-314 1.82e-12

L-ribulose-5-phosphate 4-epimerase; Validated


Pssm-ID: 235829 [Multi-domain]  Cd Length: 221  Bit Score: 67.34  E-value: 1.82e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 176 EQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrGSTNLGVNQAGftlHSAIYAARPDVRCVVHIHTPAGAAVSA----M 251
Cdd:PRK06557   41 GTDLVVIKPSGVSYDDLTPEDMVVVDLDGNVVE-GDLKPSSDTAS---HLYVYRHMPDVGGVVHTHSTYATAWAArgepI 116

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387272084 252 KCGLLPISPEAlsLGEVAYHDYHGILVDEEEKILIQKNLGPKSKVLILRNHGLVSVGESVEEA 314
Cdd:PRK06557  117 PCVLTAMADEF--GGPIPVGPFALIGDEAIGKGIVETLKGGRSPAVLMQNHGVFTIGKDAEDA 177
PRK08130 PRK08130
putative aldolase; Validated
 179-316 3.94e-08

putative aldolase; Validated


Pssm-ID: 181241 [Multi-domain]  Cd Length: 213  Bit Score: 54.50  E-value: 3.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 179 HFLIVPFGLLYSEVTASSLVKVNLQGDIV--DRGSTNLgvnqagfTLHSAIYAARPDVRCVVHIHTPAGAAVS------- 249
Cdd:PRK08130   38 GWLVTPTGSCLGRLDPARLSKVDADGNWLsgDKPSKEV-------PLHRAIYRNNPECGAVVHLHSTHLTALSclggldp 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 250 -----------AMKCGLLPISPealslgevayhdYH--GilvDEEEKILIQKnLGPKSKVLILRNHGLVSVGESVEEAFY 316
Cdd:PRK08130  111 tnvlppftpyyVMRVGHVPLIP------------YYrpG---DPAIAEALAG-LAARYRAVLLANHGPVVWGSSLEAAVN 174
PRK08087 PRK08087
L-fuculose-phosphate aldolase;
177-333 1.41e-06

L-fuculose-phosphate aldolase;


Pssm-ID: 181226 [Multi-domain]  Cd Length: 215  Bit Score: 49.74  E-value: 1.41e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 177 QEHFLIVPFGLLYSEVTASSLVKVNlqgdivDRGSTNLG-VNQAGFTLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCGL 255
Cdd:PRK08087   35 QDGMLITPTGIPYEKLTESHIVFVD------GNGKHEEGkLPSSEWRFHMAAYQTRPDANAVVHNHAVHCTAVSILNRPI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 256 --------------LPISPEAlSLG--EVAYHDYHGIlvdeeekiliqknlgPKSKVLILRNHGLVSVGESVEEAFYYIH 319
Cdd:PRK08087  109 paihymiaaaggnsIPCAPYA-TFGtrELSEHVALAL---------------KNRKATLLQHHGLIACEVNLEKALWLAH 172

                         170
                  ....*....|....
gi 1387272084 320 NLVVACEIQVRTLA 333
Cdd:PRK08087  173 EVEVLAQLYLKTLA 186
PRK06833 PRK06833
L-fuculose-phosphate aldolase;
176-338 4.30e-06

L-fuculose-phosphate aldolase;


Pssm-ID: 180717 [Multi-domain]  Cd Length: 214  Bit Score: 48.21  E-value: 4.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 176 EQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrGSTnlgVNQAGFTLHSAIYAARPDVRCVVHIHTPAGAAVSAMKCGL 255
Cdd:PRK06833   36 EQGLMAITPSGIDYFEIKPEDIVIMDLDGKVVE-GER---KPSSELDMHLIFYRNREDINAIVHTHSPYATTLACLGWEL 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 256 LPISPE-ALSLGEVAYHDYHGI----LVDEEEKILIQKnlgpksKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVR 330
Cdd:PRK06833  112 PAVHYLiAVAGPNVRCAEYATFgtkeLAENAFEAMEDR------RAVLLANHGLLAGANNLKNAFNIAEEIEFCAEIYYQ 185


                  ....*...
gi 1387272084 331 TlASAGGP 338
Cdd:PRK06833  186 T-KSIGEP 192
araD PRK13145
L-ribulose-5-phosphate 4-epimerase; Provisional
 173-323 1.21e-04

L-ribulose-5-phosphate 4-epimerase; Provisional


Pssm-ID: 183870 [Multi-domain]  Cd Length: 234  Bit Score: 44.05  E-value: 1.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 173 VSSEQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVDrGSTNlgvNQAGFTLHSAIYAARPDVRCVVHIHTPAGA----AV 248
Cdd:PRK13145   33 VCRELGRIVIKPSGVDYDELTPENMVVTDLDGNVVE-GDLN---PSSDLPTHVELYKAWPEVGGIVHTHSTEAVgwaqAG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 249 SAMKC----------GLLPISpEALSLGEV--AYHDYHGILVDEEEKiliQKNLGPKS-KVLILRNHGLVSVGESVEEAF 315
Cdd:PRK13145  109 RDIPFygtthadyfyGPIPCA-RSLTKDEVngAYEKETGSVIIEEFE---KRGLDPMAvPGIVVRNHGPFTWGKNPEQAV 184


                  ....*...
gi 1387272084 316 YyiHNLVV 323
Cdd:PRK13145  185 Y--HSVVL 190
sgaE PRK12348
L-ribulose-5-phosphate 4-epimerase; Reviewed
 176-327 1.58e-04

L-ribulose-5-phosphate 4-epimerase; Reviewed


Pssm-ID: 183460  Cd Length: 228  Bit Score: 43.64  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 176 EQEHFLIVPFGLLYSEVTASSLVKVNLQGDIVD---RGSTNLGVnqagftlHSAIYAARPDVRCVVHIHTP-------AG 245
Cdd:PRK12348   34 ERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEgeyRPSSDTAT-------HLELYRRYPSLGGIVHTHSThatawaqAG 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 246 AAVSAMKC-------GLLPISpEALSLGEVAyHDYHgilvDEEEKILIQkNLGPKSKV----LILRNHGLVSVGESVEEA 314
Cdd:PRK12348  107 LAIPALGTthadyffGDIPCT-RGLSEEEVQ-GEYE----LNTGKVIIE-TLGNAEPLhtpgIVVYQHGPFAWGKDAHDA 179

                         170
                  ....*....|...
gi 1387272084 315 fyyIHNLVVACEI 327
Cdd:PRK12348  180 ---VHNAVVMEEV 189
PRK08660 PRK08660
aldolase;
180-327 8.09e-03

aldolase;


Pssm-ID: 181527 [Multi-domain]  Cd Length: 181  Bit Score: 38.01  E-value: 8.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387272084 180 FLIVPFGLLYSEVTASSLVKVNLQG-DIVDRG-STNLGVnqagftlHSAIYAaRPDVRCVVHIHTPAGAAVSAMKCGLLP 257
Cdd:PRK08660   33 LLITRTGSMLDEITEGDVIEVGIDDdGSVDPLaSSETPV-------HRAIYR-RTSAKAIVHAHPPYAVALSLLEDEIVP 104

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387272084 258 ISPEALS-LGE--VAYHDYHGILVDEEEKILIQKNlgpksKVLILRNHGLVSVGESVEEAFYYIHNLVVACEI 327
Cdd:PRK08660  105 LDSEGLYfLGTipVVGGDIGSGELAENVARALSEH-----KGVVVRGHGTFAIGKTLEEAYIYTSQLEHSCKV 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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