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Conserved domains on  [gi|1390106851|ref|XP_025005347|]
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meiotic nuclear division protein 1 homolog isoform X6 [Gallus gallus]

Protein Classification

meiotic nuclear division 1 family protein( domain architecture ID 15633011)

meiotic nuclear division 1 (MND1) family protein such as MND1 homolog that is required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis

Gene Ontology:  GO:0003690|GO:0007131
PubMed:  11940665|25740648
SCOP:  4004373|4007688

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mnd1 pfam03962
Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein ...
 16-82 5.28e-28

Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.


:

Pssm-ID: 461112  Cd Length: 60  Bit Score: 101.04  E-value: 5.28e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390106851  16 MMEIFFETcllcfmqKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFP 82
Cdd:pfam03962   1 ILEIFHET-------KDFFTLKELEKLAPKEKGIVSQSVKDVLQSLVDDGLVDVEKIGSSNYYWSFP 60
COG5124 super family cl34914
Protein predicted to be involved in meiotic recombination [Cell division and chromosome ...
 5-197 1.13e-21

Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only];


The actual alignment was detected with superfamily member COG5124:

Pssm-ID: 227453 [Multi-domain]  Cd Length: 209  Bit Score: 88.86  E-value: 1.13e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851   5 KGLSFEEKRARMMEIFFETcllcfmqKDVFQLKDIEKIASKdKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSK 84
Cdd:COG5124     4 KGLSLAEKRRRLEAIFHDS-------KDFFQLKEVEKLGSK-KQIVLMTVKDLLQQLVDDGVVSVEKCGTSNIYWSFKSQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851  85 ALHARKRKLEELQtQECFEVRSlyafcqfhlifsvfaETSQKKEILQKgmEKSKIGRENTAERAALMKE--LAALQQKKE 162
Cdd:COG5124    76 TLQKLYDSSELLK-KKIQEVKQ---------------DIATYKEEIDK--EKATRRKKFTEGQKNYNREalLEKRKKEQD 137

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1390106851 163 QLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTT 197
Cdd:COG5124   138 EIKKKLNSLQKIEPIRWDAAKIQEKKKKVHLNKTT 172
 
Name Accession Description Interval E-value
Mnd1 pfam03962
Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein ...
 16-82 5.28e-28

Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.


Pssm-ID: 461112  Cd Length: 60  Bit Score: 101.04  E-value: 5.28e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390106851  16 MMEIFFETcllcfmqKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFP 82
Cdd:pfam03962   1 ILEIFHET-------KDFFTLKELEKLAPKEKGIVSQSVKDVLQSLVDDGLVDVEKIGSSNYYWSFP 60
COG5124 COG5124
Protein predicted to be involved in meiotic recombination [Cell division and chromosome ...
 5-197 1.13e-21

Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only];


Pssm-ID: 227453 [Multi-domain]  Cd Length: 209  Bit Score: 88.86  E-value: 1.13e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851   5 KGLSFEEKRARMMEIFFETcllcfmqKDVFQLKDIEKIASKdKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSK 84
Cdd:COG5124     4 KGLSLAEKRRRLEAIFHDS-------KDFFQLKEVEKLGSK-KQIVLMTVKDLLQQLVDDGVVSVEKCGTSNIYWSFKSQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851  85 ALHARKRKLEELQtQECFEVRSlyafcqfhlifsvfaETSQKKEILQKgmEKSKIGRENTAERAALMKE--LAALQQKKE 162
Cdd:COG5124    76 TLQKLYDSSELLK-KKIQEVKQ---------------DIATYKEEIDK--EKATRRKKFTEGQKNYNREalLEKRKKEQD 137

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1390106851 163 QLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTT 197
Cdd:COG5124   138 EIKKKLNSLQKIEPIRWDAAKIQEKKKKVHLNKTT 172
DivIC pfam04977
Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and ...
 145-182 2.64e-03

Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.


Pssm-ID: 428231 [Multi-domain]  Cd Length: 69  Bit Score: 35.27  E-value: 2.64e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1390106851 145 AERAALMKELAALQQKKEQLKAEIEKYKeYDPDVVEEM 182
Cdd:pfam04977  13 QEIAQLQAEIAKLKQENEELEAEIKDLK-SDPDYIEER 49
 
Name Accession Description Interval E-value
Mnd1 pfam03962
Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein ...
 16-82 5.28e-28

Mnd1 HTH domain; This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.


Pssm-ID: 461112  Cd Length: 60  Bit Score: 101.04  E-value: 5.28e-28
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390106851  16 MMEIFFETcllcfmqKDVFQLKDIEKIASKDKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFP 82
Cdd:pfam03962   1 ILEIFHET-------KDFFTLKELEKLAPKEKGIVSQSVKDVLQSLVDDGLVDVEKIGSSNYYWSFP 60
COG5124 COG5124
Protein predicted to be involved in meiotic recombination [Cell division and chromosome ...
 5-197 1.13e-21

Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only];


Pssm-ID: 227453 [Multi-domain]  Cd Length: 209  Bit Score: 88.86  E-value: 1.13e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851   5 KGLSFEEKRARMMEIFFETcllcfmqKDVFQLKDIEKIASKdKGITSMSVKEVLQSLVDDGMVDTDRIGTSNYFWAFPSK 84
Cdd:COG5124     4 KGLSLAEKRRRLEAIFHDS-------KDFFQLKEVEKLGSK-KQIVLMTVKDLLQQLVDDGVVSVEKCGTSNIYWSFKSQ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390106851  85 ALHARKRKLEELQtQECFEVRSlyafcqfhlifsvfaETSQKKEILQKgmEKSKIGRENTAERAALMKE--LAALQQKKE 162
Cdd:COG5124    76 TLQKLYDSSELLK-KKIQEVKQ---------------DIATYKEEIDK--EKATRRKKFTEGQKNYNREalLEKRKKEQD 137

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1390106851 163 QLKAEIEKYKEYDPDVVEEMQMNRQQSIWSCFKTT 197
Cdd:COG5124   138 EIKKKLNSLQKIEPIRWDAAKIQEKKKKVHLNKTT 172
FtsB COG2919
Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning];
145-181 1.76e-03

Cell division protein FtsB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442163 [Multi-domain]  Cd Length: 96  Bit Score: 36.78  E-value: 1.76e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1390106851 145 AERAALMKELAALQQKKEQLKAEIEKYKEyDPDVVEE 181
Cdd:COG2919    36 QEIAELEAENAKLKARNAELEAEVADLKD-GPDYIEE 71
DivIC pfam04977
Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and ...
 145-182 2.64e-03

Septum formation initiator; DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.


Pssm-ID: 428231 [Multi-domain]  Cd Length: 69  Bit Score: 35.27  E-value: 2.64e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1390106851 145 AERAALMKELAALQQKKEQLKAEIEKYKeYDPDVVEEM 182
Cdd:pfam04977  13 QEIAQLQAEIAKLKQENEELEAEIKDLK-SDPDYIEER 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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