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Conserved domains on  [gi|1443618787|ref|XP_025907570|]
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heparan sulfate glucosamine 3-O-sulfotransferase 1-like [Nothoprocta perdicaria]

Protein Classification

sulfotransferase family protein( domain architecture ID 229543)

sulfotransferase family protein may utilize 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to its substrate(s)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sulfotransfer_1 super family cl21551
Sulfotransferase domain;
57-298 1.58e-26

Sulfotransferase domain;


The actual alignment was detected with superfamily member pfam00685:

Pssm-ID: 473908 [Multi-domain]  Cd Length: 253  Bit Score: 104.73  E-value: 1.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787  57 PQTIIIGVRKGGTRALLEMLDIHPNI--VVAATEVHFFDWdENYVKGIDWYRSLMPFSYGNQI-TIEKTPG--YFTS--P 129
Cdd:pfam00685   2 DDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVAEGPvRLNALPSprIIKThlP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 130 QAPERIHDMNSSIKLLLILRDPTERVISDYTQVYYNRVESHKPVQLFEDIVIKNGALNtkykaiqRSLYDVHMEKWLKHF 209
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVN-------CGSYFDHVKGWWKLR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 210 SLDQIHIVDGNTLIKDPLPELQKVEKFLNLPP-----RIMSSNFYFNQTKGFYC-----IRSDGRE---RCLHESKgRPH 276
Cdd:pfam00685 154 PPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPClnyskLPKEVSPffrKGLVGDW-KNY 232

                         250       260
                  ....*....|....*....|..
gi 1443618787 277 pvVNNTVLEQLYSYFREHNAKF 298
Cdd:pfam00685 233 --FTPEQAEKFDEIYQEKMKGT 252
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
57-298 1.58e-26

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 104.73  E-value: 1.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787  57 PQTIIIGVRKGGTRALLEMLDIHPNI--VVAATEVHFFDWdENYVKGIDWYRSLMPFSYGNQI-TIEKTPG--YFTS--P 129
Cdd:pfam00685   2 DDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVAEGPvRLNALPSprIIKThlP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 130 QAPERIHDMNSSIKLLLILRDPTERVISDYTQVYYNRVESHKPVQLFEDIVIKNGALNtkykaiqRSLYDVHMEKWLKHF 209
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVN-------CGSYFDHVKGWWKLR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 210 SLDQIHIVDGNTLIKDPLPELQKVEKFLNLPP-----RIMSSNFYFNQTKGFYC-----IRSDGRE---RCLHESKgRPH 276
Cdd:pfam00685 154 PPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPClnyskLPKEVSPffrKGLVGDW-KNY 232

                         250       260
                  ....*....|....*....|..
gi 1443618787 277 pvVNNTVLEQLYSYFREHNAKF 298
Cdd:pfam00685 233 --FTPEQAEKFDEIYQEKMKGT 252
 
Name Accession Description Interval E-value
Sulfotransfer_1 pfam00685
Sulfotransferase domain;
57-298 1.58e-26

Sulfotransferase domain;


Pssm-ID: 425820 [Multi-domain]  Cd Length: 253  Bit Score: 104.73  E-value: 1.58e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787  57 PQTIIIGVRKGGTRALLEMLDIHPNI--VVAATEVHFFDWdENYVKGIDWYRSLMPFSYGNQI-TIEKTPG--YFTS--P 129
Cdd:pfam00685   2 DDVLIVTYPKSGTTWLQEILSLIPNRgdFEKSEEPHLFNN-HNRSPFLEWYPGDTYFDVAEGPvRLNALPSprIIKThlP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 130 QAPERIHDMNSSIKLLLILRDPTERVISDYTQVYYNRVESHKPVQLFEDIVIKNGALNtkykaiqRSLYDVHMEKWLKHF 209
Cdd:pfam00685  81 LHLLPKSLWDPNAKIIYLVRNPKDVAVSYYHFFRMAKLLKAPGTPFEFVEDFLNGKVN-------CGSYFDHVKGWWKLR 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 210 SLDQIHIVDGNTLIKDPLPELQKVEKFLNLPP-----RIMSSNFYFNQTKGFYC-----IRSDGRE---RCLHESKgRPH 276
Cdd:pfam00685 154 PPGNILFLRYEDLKKDPRGEIKKIAEFLGIPLteeelDKIVKHLSFENMKGNPClnyskLPKEVSPffrKGLVGDW-KNY 232

                         250       260
                  ....*....|....*....|..
gi 1443618787 277 pvVNNTVLEQLYSYFREHNAKF 298
Cdd:pfam00685 233 --FTPEQAEKFDEIYQEKMKGT 252
Sulfotransfer_3 pfam13469
Sulfotransferase family;
60-240 2.59e-11

Sulfotransferase family;


Pssm-ID: 463887  Cd Length: 173  Bit Score: 61.15  E-value: 2.59e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787  60 IIIGVRKGGTRALLEMLDIHPniVVAATEVHFFDWDENYVKGIDW---YRSLMPFSYGNQITIEKTPGYFtspQAPERIH 136
Cdd:pfam13469   2 FIVGLPRSGTTLLHRLLAAHP--DVRPPEETWFVIPRILALLQAWgksLEALARVPSYARWLCDKSPSHL---FHLDLLL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1443618787 137 DMNSSIKLLLILRDPTERVISDYTQVYYNRVESHKPVQLFEDivikNGALNTKYKAIQRSlydvhMEKWLKHFSlDQIHI 216
Cdd:pfam13469  77 KAFPDAKFIHLHRDPVDTVISSYCSLFGFTLSSYSTAFLRDI----GLALARWSRAYERL-----MAARARVPP-GRFLD 146

                         170       180
                  ....*....|....*....|....
gi 1443618787 217 VDGNTLIKDPLPELQKVEKFLNLP 240
Cdd:pfam13469 147 VRYEDLVADPEGTLRRILEFLGLP 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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