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Conserved domains on  [gi|1720421879|ref|XP_030098268|]
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CCR4-NOT transcription complex subunit 3 isoform X8 [Mus musculus]

Protein Classification

CNOT2/3/5 family protein( domain architecture ID 13694845)

CNOT2/3/5 family protein is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 1.75e-130

Not1 N-terminal domain, CCR4-Not complex component;


:

Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.13  E-value: 1.75e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720421879 161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
618-743 1.03e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


:

Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 1.03e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1720421879 698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
297-564 2.57e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.99  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 297 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 376
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 377 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 450
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 451 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 528
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1720421879 529 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 564
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 1.75e-130

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.13  E-value: 1.75e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720421879 161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
618-743 1.03e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 1.03e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1720421879 698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
643-746 4.17e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 4.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 643 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 716
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143
                          90       100       110
                  ....*....|....*....|....*....|
gi 1720421879 717 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 746
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
8-216 1.83e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   8 QGEID----------RCLKKVSeGVEQFEDIWQKLhnaananqkekyeADLKKEIK-KLQRLRDQIKtwvASNEIKDkrq 76
Cdd:PRK03918  134 QGEIDailesdesreKVVRQIL-GLDDYENAYKNL-------------GEVIKEIKrRIERLEKFIK---RTENIEE--- 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  77 lienrkLIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEVGQwLTNTIDTLNMQVDQFESEVESLsvqtrkk 156
Cdd:PRK03918  194 ------LIKEKEKELEEVLREINEI--SSELPELREELEKLEKEVKELEE-LKEEIEELEKELESLEGSKRKL------- 257
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 157 kgdkdkQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQD 216
Cdd:PRK03918  258 ------EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE 311
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
297-564 2.57e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.99  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 297 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 376
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 377 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 450
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 451 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 528
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1720421879 529 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 564
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PHA03247 PHA03247
large tegument protein UL36; Provisional
314-657 2.11e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  314 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYA------------------QAV 375
Cdd:PHA03247  2577 PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdphppptvppperprDDP 2656
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  376 APPNASGPSNAQ--------------PRPPSA---------------QPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATS 426
Cdd:PHA03247  2657 APGRVSRPRRARrlgraaqassppqrPRRRAArptvgsltsladpppPPPTPEPAPHALVSATPLPPGPAAARQASPALP 2736
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  427 YSSVVADSPAEVTLSSSGGSSASSQAlgpTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSP 506
Cdd:PHA03247  2737 AAPAPPAVPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA 2813
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  507 TPSFSEAKAAGTLLNGPPQFST-TPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsa 575
Cdd:PHA03247  2814 PAAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL------- 2886
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  576 pptsSQPPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHS 655
Cdd:PHA03247  2887 ----ARPAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTT 2947

                   ..
gi 1720421879  656 DT 657
Cdd:PHA03247  2948 DP 2949
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
3-149 4.68e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIwqklhnaananqkEKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIE 79
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDL-------------TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQ 486
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  80 NRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESL 149
Cdd:TIGR04523 487 KQKELKSKEKELKKLNEEKKE---------LEEKVKDLTKKISS----LKEKIEKLESEKKEKESKISDL 543
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
338-491 6.58e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 39.63  E-value: 6.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 338 PGNNGASTPAAPTSALGpkasPAPSHNSGTPAPYAQAVAPPNASGPSnaqpRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 417
Cdd:COG5164    48 AQNQGSTTPAGNTGGTR----PAGNQGATGPAQNQGGTTPAQNQGGT----RPAGNTGGTTPAGDGGATGPPDDGGATGP 119
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720421879 418 AGKqNGATSYSSVVADSPAEVTlsssGGSSASSQALGPT--SGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGG 491
Cdd:COG5164   120 PDD-GGSTTPPSGGSTTPPGDG----GSTPPGPGSTGPGgsTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGE 190
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
3-229 1.75e-130

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 386.13  E-value: 1.75e-130
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRDQIKTWVASNEIKDKRQLIENRK 82
Cdd:pfam04065   1 AARKLQQEIDRTLKKVAEGLEEFDDIYEKLESATNSSQKEKLEADLKKEIKKLQRLRDQIKTWLSSNDIKDKKKLLENRK 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  83 LIETQMERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRkKKGDK 160
Cdd:pfam04065  81 LIEEAMERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKK-KKKKD 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720421879 161 DKQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 229
Cdd:pfam04065 160 SEKARLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
618-743 1.03e-56

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 1.03e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 618 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 697
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1720421879 698 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 743
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
643-746 4.17e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 4.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 643 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 716
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143
                          90       100       110
                  ....*....|....*....|....*....|
gi 1720421879 717 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 746
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
8-216 1.83e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   8 QGEID----------RCLKKVSeGVEQFEDIWQKLhnaananqkekyeADLKKEIK-KLQRLRDQIKtwvASNEIKDkrq 76
Cdd:PRK03918  134 QGEIDailesdesreKVVRQIL-GLDDYENAYKNL-------------GEVIKEIKrRIERLEKFIK---RTENIEE--- 193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  77 lienrkLIETQMERFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEVGQwLTNTIDTLNMQVDQFESEVESLsvqtrkk 156
Cdd:PRK03918  194 ------LIKEKEKELEEVLREINEI--SSELPELREELEKLEKEVKELEE-LKEEIEELEKELESLEGSKRKL------- 257
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 157 kgdkdkQDRIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQD 216
Cdd:PRK03918  258 ------EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE 311
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
297-564 2.57e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 47.99  E-value: 2.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 297 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 376
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 377 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 450
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 451 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 528
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1720421879 529 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 564
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PHA03247 PHA03247
large tegument protein UL36; Provisional
314-657 2.11e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 2.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  314 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYA------------------QAV 375
Cdd:PHA03247  2577 PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdphppptvppperprDDP 2656
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  376 APPNASGPSNAQ--------------PRPPSA---------------QPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATS 426
Cdd:PHA03247  2657 APGRVSRPRRARrlgraaqassppqrPRRRAArptvgsltsladpppPPPTPEPAPHALVSATPLPPGPAAARQASPALP 2736
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  427 YSSVVADSPAEVTLSSSGGSSASSQAlgpTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSP 506
Cdd:PHA03247  2737 AAPAPPAVPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA 2813
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  507 TPSFSEAKAAGTLLNGPPQFST-TPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsa 575
Cdd:PHA03247  2814 PAAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL------- 2886
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  576 pptsSQPPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHS 655
Cdd:PHA03247  2887 ----ARPAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTT 2947

                   ..
gi 1720421879  656 DT 657
Cdd:PHA03247  2948 DP 2949
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
342-483 2.30e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 2.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 342 GASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSnsgtgggagkQ 421
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPP----------P 458
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720421879 422 NGATSYSSVVADSPAEvtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVAS 483
Cdd:PRK07764  459 AAAPSAQPAPAPAAAP---------EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
212-493 2.77e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 2.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  212 DSSQDPDFEEN-EFLYDDLDLEDIPQALVATS----------PPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTE 280
Cdd:PHA03307    30 DAADDLLSGSQgQLVSDSAELAAVTVVAGAAAcdrfepptgpPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP 109
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  281 NSEDDKKRGRSTDsevsqsPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTP--AAPTSALGPKAS 358
Cdd:PHA03307   110 GPSSPDPPPPTPP------PASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSrqAALPLSSPEETA 183
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  359 PAPSHNSGTPAPYAQAVAPPNASGP--SNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVvaDSPA 436
Cdd:PHA03307   184 RAPSSPPAEPPPSTPPAAASPRPPRrsSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL--PRPA 261
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720421879  437 EVTLSSSGGSSASSQALGPTSGP---------HNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPS 493
Cdd:PHA03307   262 PITLPTRIWEASGWNGPSSRPGPassssspreRSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
332-645 3.12e-04

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 44.18  E-value: 3.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 332 SALSSTPGNNGASTPAA----PTSALGPKASPAPShnsgTPAPYAQAVAPPNASGPSNAQPRPPSAqpsggsgggsggss 407
Cdd:pfam17823 117 AAASSSPSSAAQSLPAAiaalPSEAFSAPRAAACR----ANASAAPRAAIAAASAPHAASPAPRTA-------------- 178
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 408 snsnsGTGGGAGKQNGATSYSSVVADSPAEVTLSssggssassqalgPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGN 487
Cdd:pfam17823 179 -----ASSTTAASSTTAASSAPTTAASSAPATLT-------------PARGISTAATATGHPAAGTALAAVGNSSPAAGT 240
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 488 NSGGPSLLVPLPVNPPSSPTPSFseAKAAGTLLNGPPQfSTTPeikAPEPLSSLKSMAERAAISSGIEDPVPTLHLT-DR 566
Cdd:pfam17823 241 VTAAVGTVTPAALATLAAAAGTV--ASAAGTINMGDPH-ARRL---SPAKHMPSDTMARNPAAPMGAQAQGPIIQVStDQ 314
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 567 DIIlssTSAPPTSSQPPLQLSEVNIPLSLGVCPLGPVSLTKEQLYQQAmeeAAWHHMPHPSDSERIRQYLP-RNPCPTPP 645
Cdd:pfam17823 315 PVH---NTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPS---ASPVPVLHTSMIPEVEATSPtTQPSPLLP 388
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
338-556 1.34e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 1.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 338 PGNNGASTPAAPTSALGPKASPAPSHNSGTPAPyAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 417
Cdd:PRK07764  592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 418 AGKQNGATSYSSVVADSPAevtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVP 497
Cdd:PRK07764  671 AKAGGAAPAAPPPAPAPAA----------PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720421879 498 LPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPeiKAPEPLSSLKSMAERAAISSGIED 556
Cdd:PRK07764  741 LPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAA--PPPSPPSEEEEMAEDDAPSMDDED 797
PHA03247 PHA03247
large tegument protein UL36; Provisional
307-666 1.44e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  307 PVHSNQHPQSPavpPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPkASPAPSHNSGTPAPYAQAVAPPNASGPsnA 386
Cdd:PHA03247  2694 SLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAGP--P 2767
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  387 QPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPST 466
Cdd:PHA03247  2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  467 SKESStaapsgAGNVASGSGNNSGGPSLLVPLPVNPPSSPTpsfseakaAGTLLNGPPQFSTTPEIKAPEPLsslksmaE 546
Cdd:PHA03247  2848 PSLPL------GGSVAPGGDVRRRPPSRSPAAKPAAPARPP--------VRRLARPAVSRSTESFALPPDQP-------E 2906
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  547 RAAISSGIEDPVPTlhltdrdiilsSTSAPPTSSQPPLQlsevniPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHP 626
Cdd:PHA03247  2907 RPPQPQAPPPPQPQ-----------PQPPPPPQPQPPPP------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1720421879  627 SDSERIRQylpRNPCPTPPYHHQMPPPHSDTVEFYQRLST 666
Cdd:PHA03247  2970 GRVAVPRF---RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PHA03247 PHA03247
large tegument protein UL36; Provisional
314-653 2.93e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 2.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  314 PQSPAVpptypsgppPTTSALSSTPGNNGA---STPAAPTSALGPKASP------APSHNSGTPApyaqAVAPPNASGPS 384
Cdd:PHA03247  2554 PLPPAA---------PPAAPDRSVPPPRPAprpSEPAVTSRARRPDAPPqsarprAPVDDRGDPR----GPAPPSPLPPD 2620
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  385 NAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSvVADSPAEVTLSSSGGSSASSQALGPTSG------ 458
Cdd:PHA03247  2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQASSPPQRPRRRAARPTVGsltsla 2699
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  459 -PHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEP 537
Cdd:PHA03247  2700 dPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGP 2779
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  538 ---------------LSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLG--VCPL 600
Cdd:PHA03247  2780 prrltrpavaslsesRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPG 2859
                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720421879  601 GPVSltKEQLYQQAMEEAAwhHMPHPSDSERIRQYLPRN--PCPTPPYHHQMPPP 653
Cdd:PHA03247  2860 GDVR--RRPPSRSPAAKPA--APARPPVRRLARPAVSRSteSFALPPDQPERPPQ 2910
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
299-478 3.97e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 299 SPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPS-------HNSGTPAPY 371
Cdd:PRK07764  600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASdggdgwpAKAGGAAPA 679
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 372 AQAVAPPNASGPSNAQPRPPSAQPsggsgggSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSAssq 451
Cdd:PRK07764  680 APPPAPAPAAPAAPAGAAPAQPAP-------APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP--- 749
                         170       180
                  ....*....|....*....|....*..
gi 1720421879 452 ALGPTSGPHNPAPSTSKESSTAAPSGA 478
Cdd:PRK07764  750 DPAGAPAQPPPPPAPAPAAAPAAAPPP 776
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
334-517 4.10e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 4.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 334 LSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSG 413
Cdd:PRK07003  356 LAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 414 TGGgAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKE----------SSTAAPSGAGNVAS 483
Cdd:PRK07003  436 ADR-GDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFepapraaapsAATPAAVPDARAPA 514
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1720421879 484 GSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAG 517
Cdd:PRK07003  515 AASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
3-149 4.68e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 4.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIwqklhnaananqkEKYEADLKKEIKKLQRLRDQIKTWVA--SNEIKD-KRQLIE 79
Cdd:TIGR04523 420 EKELLEKEIERLKETIIKNNSEIKDL-------------TNQDSVKELIIKNLDNTRESLETQLKvlSRSINKiKQNLEQ 486
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879  80 NRKLIETQMERFKVVERETKTkayskeglgLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESL 149
Cdd:TIGR04523 487 KQKELKSKEKELKKLNEEKKE---------LEEKVKDLTKKISS----LKEKIEKLESEKKEKESKISDL 543
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
314-493 5.21e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 5.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 314 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAP--SHNSGTPAPYAQAVAPPNASGPS--NAQPR 389
Cdd:PRK07003  385 ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPpaTADRGDDAADGDAPVPAKANARAsaDSRCD 464
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 390 PPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKE 469
Cdd:PRK07003  465 ERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAA 544
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1720421879 470 SSTAAPSG------AG-NVASGSGNNSGGPS 493
Cdd:PRK07003  545 RAGGAAAAldvlrnAGmRVSSDRGARAAAAA 575
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
339-549 5.49e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 40.24  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 339 GNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPsggsgggsggsSSNSNSGTGGGA 418
Cdd:PRK12323  367 QSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP-----------ARRSPAPEALAA 435
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 419 GKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSgPHNPAPSTSKESSTAAPSGAGNVASgsgnNSGGPSLLVPL 498
Cdd:PRK12323  436 ARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAA-AAAAAPARAAPAAAPAPADDDPPPW----EELPPEFASPA 510
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1720421879 499 PVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAA 549
Cdd:PRK12323  511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
338-491 6.58e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 39.63  E-value: 6.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 338 PGNNGASTPAAPTSALGpkasPAPSHNSGTPAPYAQAVAPPNASGPSnaqpRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 417
Cdd:COG5164    48 AQNQGSTTPAGNTGGTR----PAGNQGATGPAQNQGGTTPAQNQGGT----RPAGNTGGTTPAGDGGATGPPDDGGATGP 119
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720421879 418 AGKqNGATSYSSVVADSPAEVTlsssGGSSASSQALGPT--SGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGG 491
Cdd:COG5164   120 PDD-GGSTTPPSGGSTTPPGDG----GSTPPGPGSTGPGgsTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGE 190
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
3-153 8.59e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 39.62  E-value: 8.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879   3 DKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKK-EIKKLQRLRDQIKTWVAS--NEIKDKRQLIE 79
Cdd:TIGR04523 322 KLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQnEIEKLKKENQSYKQEIKNleSQINDLESKIQ 401
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720421879  80 NRKLIETQME-RFKVVERETKTKaySKEGLGLAQKVDPAQKEKEEvgqwLTNTIDTLNMQVDQFESEVESLSVQT 153
Cdd:TIGR04523 402 NQEKLNQQKDeQIKKLQQEKELL--EKEIERLKETIIKNNSEIKD----LTNQDSVKELIIKNLDNTRESLETQL 470
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
295-393 9.39e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 39.37  E-value: 9.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720421879 295 EVSQSPAKNGSKPvhSNQHPQSP---AVPPTYPSGPPPTTSALSSTPGNNG-ASTPAAPTSALGPKASPAP-SHNSGTPA 369
Cdd:PRK14971  358 QLAQLTQKGDDAS--GGRGPKQHikpVFTQPAAAPQPSAAAAASPSPSQSSaAAQPSAPQSATQPAGTPPTvSVDPPAAV 435
                          90       100
                  ....*....|....*....|....
gi 1720421879 370 PYAQAVAPPNASGPSNAQPRPPSA 393
Cdd:PRK14971  436 PVNPPSTAPQAVRPAQFKEEKKIP 459
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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