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Conserved domains on  [gi|1907179560|ref|XP_036008824|]
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CCR4-NOT transcription complex subunit 3 isoform X9 [Mus musculus]

Protein Classification

CNOT2/3/5 family protein( domain architecture ID 13694845)

CNOT2/3/5 family protein is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
1-143 1.02e-65

Not1 N-terminal domain, CCR4-Not complex component;


:

Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 215.87  E-value: 1.02e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560   1 MERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKqd 78
Cdd:pfam04065  86 MERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKKKKKKDSEKA-- 163

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907179560  79 RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 143
Cdd:pfam04065 164 RLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 532-657 3.48e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


:

Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 3.48e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 532 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 611
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179560 612 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 657
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
Herpes_BLLF1 super family cl37540
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 211-478 1.79e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


The actual alignment was detected with superfamily member pfam05109:

Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 211 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 290
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 291 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 364
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 365 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 442
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179560 443 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 478
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
1-143 1.02e-65

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 215.87  E-value: 1.02e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560   1 MERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKqd 78
Cdd:pfam04065  86 MERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKKKKKKDSEKA-- 163

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907179560  79 RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 143
Cdd:pfam04065 164 RLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 532-657 3.48e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 3.48e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 532 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 611
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179560 612 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 657
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
557-660 3.68e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 3.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 557 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 630
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                          90       100       110
                  ....*....|....*....|....*....|
gi 1907179560 631 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 660
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 211-478 1.79e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 211 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 290
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 291 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 364
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 365 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 442
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179560 443 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 478
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 256-397 3.41e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 256 GASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSgtgggagkq 335
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPA--------- 459

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907179560 336 ngatsyssvvADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVAS 397
Cdd:PRK07764  460 ----------AAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
 
Name Accession Description Interval E-value
Not3 pfam04065
Not1 N-terminal domain, CCR4-Not complex component;
1-143 1.02e-65

Not1 N-terminal domain, CCR4-Not complex component;


Pssm-ID: 461155 [Multi-domain]  Cd Length: 228  Bit Score: 215.87  E-value: 1.02e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560   1 MERFKVVERETKTKAYSKEGLGLAQ--KVDPAQKEKEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDQKqd 78
Cdd:pfam04065  86 MERFKAVEKESKTKAFSKEGLSLAAasKLDPKEKEKAEARDWLSDSIDELNRQIEALEAEIESLQAQKKKKKKDSEKA-- 163

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907179560  79 RIEGLKRHIEKHRYHVRMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDL 143
Cdd:pfam04065 164 RLEELEKLIERHKFHIEKLELILRLLENGELDPEQVDDIKEDIEYYVESNQDPDFVEDEDIYDDL 228
NOT2_3_5 pfam04153
NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that ...
 532-657 3.48e-57

NOT2 / NOT3 / NOT5 family; NOT1, NOT2, NOT3, NOT4 and NOT5 form a nuclear complex that negatively regulates the basal and activated transcription of many genes. This family includes NOT2, NOT3 and NOT5.


Pssm-ID: 461199  Cd Length: 121  Bit Score: 188.96  E-value: 3.48e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 532 AAWHHMPHPSDSERIRQYLPRNPCPTPpyhhQMPPPHSDTVEFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFH 611
Cdd:pfam04153   1 YSTFNSPWPLDAERPYEPDFRNPACYP----QEPLPRLESPEKFSKFDDETLFYIFYSMPGDYAQYLAAKELKKRSWRYH 76

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907179560 612 TKYMMWFQRHEEPKTITDEFEQGTYIYFDYeKWGQRKKEGFTFEYR 657
Cdd:pfam04153  77 KKLRTWFTRDEEPKVITNEYERGTYIYFDY-TWEQRRKKDFTLDYE 121
CDC36 COG5601
General negative regulator of transcription subunit [Transcription];
557-660 3.68e-14

General negative regulator of transcription subunit [Transcription];


Pssm-ID: 227888  Cd Length: 172  Bit Score: 70.78  E-value: 3.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 557 TPPYHHQMPPPHSDTVEFYQR----LSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMW--FQRHEEPKTITDE 630
Cdd:COG5601    64 LPNCYPNAPNPPIFKVNIEDMkmdnFHDETLFYIFYSFPNDVLQEKAYDELLKRNWRFHKMLKCWltFNPGMSPATADHV 143

                          90       100       110
                  ....*....|....*....|....*....|
gi 1907179560 631 FEQGTYIYFDYEKWGQRKKEgFTFEYRYLE 660
Cdd:COG5601   144 KERGSYVFFDPFSWSKVSLD-FLLDYKAVR 172
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 211-478 1.79e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.91  E-value: 1.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 211 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPgnNGASTPAAPTSALGPKASPAPSHNSGTPapyAQAVA 290
Cdd:pfam05109 491 SPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTPTP--NATSPTLGKTSPTSAVTTPTPNATSPTP---AVTTP 565

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 291 PPNASGPSNAQPRPPSAqpSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSS------GGSSASS 364
Cdd:pfam05109 566 TPNATIPTLGKTSPTSA--VTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTtgqhniTSSSTSS 643

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 365 QALGPTSGPHNPAPSTSKESSTAAPsgagnvASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTL--LNGPPQFST 442
Cdd:pfam05109 644 MSLRPSSISETLSPSTSDNSTSHMP------LLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTsqASGPGNSST 717

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1907179560 443 TPEikaPEPLSSLKSMAERAAIS----SGIEDPVPTLHLT 478
Cdd:pfam05109 718 STK---PGEVNVTKGTPPKNATSpqapSGQKTAVPTVTST 754
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 256-397 3.41e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 3.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 256 GASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSgtgggagkq 335
Cdd:PRK07764  389 GGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPA--------- 459

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907179560 336 ngatsyssvvADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVAS 397
Cdd:PRK07764  460 ----------AAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAT 511
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 126-407 4.95e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.62  E-value: 4.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  126 DSSQDPDFEEN-EFLYDDLDLEDIPQALVATS----------PPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTE 194
Cdd:PHA03307    30 DAADDLLSGSQgQLVSDSAELAAVTVVAGAAAcdrfepptgpPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  195 NSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSAL-----GP 269
Cdd:PHA03307   110 GPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETarapsSP 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  270 KASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSP 349
Cdd:PHA03307   190 PAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRI 269

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907179560  350 AEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPS 407
Cdd:PHA03307   270 WEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSS 327
PHA03247 PHA03247
large tegument protein UL36; Provisional
 228-571 9.46e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.62  E-value: 9.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  228 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYA------------------QAV 289
Cdd:PHA03247  2577 PSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAAnepdphppptvppperprDDP 2656

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  290 APPNASGPSNAQ--------------PRPPSA---------------QPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATS 340
Cdd:PHA03247  2657 APGRVSRPRRARrlgraaqassppqrPRRRAArptvgsltsladpppPPPTPEPAPHALVSATPLPPGPAAARQASPALP 2736

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  341 YSSVVADSPAEVTLSSSGGSSASSQAlgpTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSP 420
Cdd:PHA03247  2737 AAPAPPAVPAGPATPGGPARPARPPT---TAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLA 2813

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  421 TPSFSEAKAAGTLLNGPPQFST-TPEIKAPEPLSSLKSM----------AERAAISSGIEDPVPTLHLTDRDIilsstsa 489
Cdd:PHA03247  2814 PAAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLggsvapggdvRRRPPSRSPAAKPAAPARPPVRRL------- 2886

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  490 pptsSQPPLQLSEVNIPLSlgvcPLGPVSLTKEQLYQQAMEEAAWHHMPhpsdserirqyLPRNPCPTPPYHHQMPPPHS 569
Cdd:PHA03247  2887 ----ARPAVSRSTESFALP----PDQPERPPQPQAPPPPQPQPQPPPPP-----------QPQPPPPPPPRPQPPLAPTT 2947


                   ..
gi 1907179560  570 DT 571
Cdd:PHA03247  2948 DP 2949
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 252-470 1.64e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 252 PGNNGASTPAAPTSALGPKASPAPSHNSGTPAPyAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGG 331
Cdd:PRK07764  592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAP-AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 332 AGKQNGATSYSSVVADSPAevtlsssggsSASSQALGPTSGPHNPAPSTSKESSTAAPSGAGNVASGSGNNSGGPSLLVP 411
Cdd:PRK07764  671 AKAGGAAPAAPPPAPAPAA----------PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907179560 412 LPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPeiKAPEPLSSLKSMAERAAISSGIED 470
Cdd:PRK07764  741 LPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAA--PPPSPPSEEEEMAEDDAPSMDDED 797
PHA03247 PHA03247
large tegument protein UL36; Provisional
 221-580 3.16e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 3.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  221 PVHSNQHPQSPavpPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPkASPAPSHNSGTPAPYAQAVAPPNASGPsnA 300
Cdd:PHA03247  2694 SLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAP-APPAVPAGPATPGGPARPARPPTTAGP--P 2767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  301 QPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPST 380
Cdd:PHA03247  2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPP 2847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  381 SKESStaapsgAGNVASGSGNNSGGPSLLVPLPVNPPSSPTpsfseakaAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAE 460
Cdd:PHA03247  2848 PSLPL------GGSVAPGGDVRRRPPSRSPAAKPAAPARPP--------VRRLARPAVSRSTESFALPPDQPERPPQPQA 2913

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  461 RAAISSGIEDPVPTLhltdrdiilsstsapptsSQPPLQlsevniPLSLGVCPLGPVSLTKEQLYQQAMEEAAWHHMPHP 540
Cdd:PHA03247  2914 PPPPQPQPQPPPPPQ------------------PQPPPP------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP 2969

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|
gi 1907179560  541 SDSERIRQylpRNPCPTPPYHHQMPPPHSDTVEFYQRLST 580
Cdd:PHA03247  2970 GRVAVPRF---RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 213-392 4.43e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 4.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 213 SPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPS-------HNSGTPAPY 285
Cdd:PRK07764  600 PPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASdggdgwpAKAGGAAPA 679

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 286 AQAVAPPNASGPSNAQPRPPSAQPsggsgggSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSAssq 365
Cdd:PRK07764  680 APPPAPAPAAPAAPAGAAPAQPAP-------APAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP--- 749

                         170       180
                  ....*....|....*....|....*..
gi 1907179560 366 ALGPTSGPHNPAPSTSKESSTAAPSGA 392
Cdd:PRK07764  750 DPAGAPAQPPPPPAPAPAAAPAAAPPP 776
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
248-431 4.58e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 4.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 248 LSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSG 327
Cdd:PRK07003  356 LAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 328 TGGgAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSK----------ESSTAAPSGAGNVAS 397
Cdd:PRK07003  436 ADR-GDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAfepapraaapSAATPAAVPDARAPA 514

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1907179560 398 GSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAG 431
Cdd:PRK07003  515 AASREDAPAAAAPPAPEARPPTPAAAAPAARAGG 548
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
228-407 6.51e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.83  E-value: 6.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 228 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAP--SHNSGTPAPYAQAVAPPNASGPS--NAQPR 303
Cdd:PRK07003  385 ARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPpaTADRGDDAADGDAPVPAKANARAsaDSRCD 464

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 304 PPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSGPHNPAPSTSKE 383
Cdd:PRK07003  465 ERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAA 544

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1907179560 384 SSTAAPSG------AG-NVASGSGNNSGGPS 407
Cdd:PRK07003  545 RAGGAAAAldvlrnAGmRVSSDRGARAAAAA 575
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
209-307 6.62e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 39.76  E-value: 6.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 209 EVSQSPAKNGSKPvhSNQHPQSP---AVPPTYPSGPPPTTSALSSTPGNNG-ASTPAAPTSALGPKASPAP-SHNSGTPA 283
Cdd:PRK14971  358 QLAQLTQKGDDAS--GGRGPKQHikpVFTQPAAAPQPSAAAAASPSPSQSSaAAQPSAPQSATQPAGTPPTvSVDPPAAV 435

                          90       100
                  ....*....|....*....|....
gi 1907179560 284 PYAQAVAPPNASGPSNAQPRPPSA 307
Cdd:PRK14971  436 PVNPPSTAPQAVRPAQFKEEKKIP 459
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
253-463 6.98e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.47  E-value: 6.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 253 GNNGASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPsggsgggsggsSSNSNSGTGGGA 332
Cdd:PRK12323  367 QSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP-----------ARRSPAPEALAA 435

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 333 GKQNGATSYSSVVADSPAEVTLSSSGGSSASSQALGPTSgPHNPAPSTSKESSTAAPSGAGNVASgsgnNSGGPSLLVPL 412
Cdd:PRK12323  436 ARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAA-AAAAAPARAAPAAAPAPADDDPPPW----EELPPEFASPA 510

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1907179560 413 PVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEPLSSLKSMAERAA 463
Cdd:PRK12323  511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
PHA03247 PHA03247
large tegument protein UL36; Provisional
 228-567 9.10e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  228 PQSPAVPPTYPSGPPPTTSALSSTPGNNGASTPAAPTSALGPKASPAPSHNSGTPApyaqAVAPPNASGPSNAQPRPPSA 307
Cdd:PHA03247  2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPR----GPAPPSPLPPDTHAPDPPPP 2629

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  308 QPSGGSGGGSGGSSSNSNSGTGGGAGKQNGATSYSSvVADSPAEVTLSSSGGSSASSQALGPTSG-------PHNPAPST 380
Cdd:PHA03247  2630 SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPR-RARRLGRAAQASSPPQRPRRRAARPTVGsltsladPPPPPPTP 2708

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  381 SKESSTAAPSGAGNVASGSGNNSGGPSLLVPLPVNPPSSPTPSFSEAKAAGTLLNGPPQFSTTPEIKAPEP--------- 451
Cdd:PHA03247  2709 EPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPprrltrpav 2788

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560  452 ------LSSLKSMAERAAISSGIEDPVPTLHLTDRDIILSSTSAPPTSSQPPLQLSEVNIPLSLG--VCPLGPVSltKEQ 523
Cdd:PHA03247  2789 aslsesRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsVAPGGDVR--RRP 2866

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1907179560  524 LYQQAMEEAAwhHMPHPSDSERIRQYLPRN--PCPTPPYHHQMPPP 567
Cdd:PHA03247  2867 PSRSPAAKPA--APARPPVRRLARPAVSRSteSFALPPDQPERPPQ 2910
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 257-371 9.92e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 38.93  E-value: 9.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907179560 257 ASTPAAPTSALGPKASPAPSHNSGTPAPYAQAVAPPNASGPSNAQPRPPSAQPSGGSGGGSGGSSSNSNSGTGGGAGKQN 336
Cdd:PRK14951  378 KKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAP 457

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1907179560 337 GATSYSSVVADSPAEVTLSSSGGSSASSQALGPTS 371
Cdd:PRK14951  458 ETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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