NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1907190984|ref|XP_036010169|]
View 

cell division cycle protein 16 homolog isoform X2 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
23-206 1.15e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  23 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 102
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 103 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 182
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                         170       180
                  ....*....|....*....|....
gi 1907190984 183 HSLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG0457   154 LEKLGRYEEALELLEKLEAAALAA 177
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
23-206 1.15e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  23 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 102
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 103 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 182
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                         170       180
                  ....*....|....*....|....
gi 1907190984 183 HSLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG0457   154 LEKLGRYEEALELLEKLEAAALAA 177
TPR_12 pfam13424
Tetratricopeptide repeat;
141-205 1.64e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.55  E-value: 1.64e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 141 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 205
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 35-202 6.50e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 6.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  35 GHSFAVESEHDQAMAAYFTAAQLMKGCHLPMlYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKT 114
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDK 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 115 AEKWFLDALEKikAIGNEVTvdkweplLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVD 194
Cdd:TIGR02917 789 AIKHYQTVVKK--APDNAVV-------LNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858


                  ....*...
gi 1907190984 195 YFHTALGL 202
Cdd:TIGR02917 859 LLRKAVNI 866
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 142-172 7.37e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.05  E-value: 7.37e-06
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907190984  142 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 172
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 155-209 1.72e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 1.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1907190984 155 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 209
Cdd:cd24142    16 FELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 155-202 3.41e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 3.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1907190984 155 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 202
Cdd:PRK02603   51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
23-206 1.15e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.15e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  23 LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEV 102
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 103 GVVAFQNGEWKTAEKWFLDALEkikaIGNEVtvdkwEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 182
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALE----LDPDD-----AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153

                         170       180
                  ....*....|....*....|....
gi 1907190984 183 HSLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG0457   154 LEKLGRYEEALELLEKLEAAALAA 177
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
67-216 1.17e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  67 YIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkIKAignevtvdKWEPLLNNLG 146
Cdd:COG0457    13 NLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE-LDP--------DDAEALNNLG 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 147 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 216
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIA 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 60-206 3.34e-16

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.07  E-value: 3.34e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  60 GCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWE 139
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE----------LDPDE 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907190984 140 P-LLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG4783    72 PeARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
89-216 1.15e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.04  E-value: 1.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  89 LSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQALV 167
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALE----------LDPDDAeALYNLGLAYLRLGRYEEALADYEQALE 70

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1907190984 168 LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 216
Cdd:COG0457    71 LDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLA 119
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 75-227 7.81e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.03  E-value: 7.81e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  75 TNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKK 154
Cdd:COG3914    91 LGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL---------NPDFAEAYLNLGEALRRLGR 161

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 155 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIeMYIGDSEAY 227
Cdd:COG3914   162 LEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFAL-RQACDWEVY 233
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 31-226 4.06e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.30  E-value: 4.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  31 WIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNG 110
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 111 EWKTAEKWFLDALEkikaignevTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFE 190
Cdd:COG2956    91 LLDRAEELLEKLLE---------LDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD 161

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907190984 191 NAVDYFHTALGLRRDDTFSVTMLGHcIEMYIGDSEA 226
Cdd:COG2956   162 EAIEALEKALKLDPDCARALLLLAE-LYLEQGDYEE 196
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 14-216 7.17e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.53  E-value: 7.17e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG2956    28 IDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDP 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAekwfLDALEKIKAIGnevtvDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNA 173
Cdd:COG2956   108 DDAEALRLLAEIYEQEGDWEKA----IEVLERLLKLG-----PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1907190984 174 STYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 216
Cdd:COG2956   179 RALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 14-226 5.29e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 5.29e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG2956    62 IRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKaignevtvdKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNA 173
Cdd:COG2956   142 ENAHAYCELAELYLEQGDYDEAIEALEKALKLDP---------DCARALLLLAELYLEQGDYEEAIAALERALEQDPDYL 212

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 174 STYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFsVTMLGHCIEMYIGDSEA 226
Cdd:COG2956   213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALADLLERKEGLEAA 264
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 63-214 7.73e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.67  E-value: 7.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  63 LPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLL 142
Cdd:COG2956     9 LGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER---------DPDRAEAL 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907190984 143 NNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 214
Cdd:COG2956    80 LELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELA 151
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 43-186 8.72e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.70  E-value: 8.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  43 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDA 122
Cdd:COG3914    93 RYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRA 172

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907190984 123 LEkikaigneVTVDKWEpLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAigYIHSLM 186
Cdd:COG3914   173 LE--------LDPDNAE-ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN--LLFALR 225
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
105-205 1.07e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.49  E-value: 1.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 105 VAFQNGEWKTAEKWFLDALEKIKAIGNevtvdkwepLLNNLGHVCRKLKKYAEALDYhRQALVLIPQNASTYSAIGYIHS 184
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNAD---------ALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLL 70

                          90       100
                  ....*....|....*....|.
gi 1907190984 185 LMGNFENAVDYFHTALGLRRD 205
Cdd:COG3063    71 ELGDYDEALAYLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 14-200 2.41e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.13  E-value: 2.41e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG2956    96 EELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDP 175

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNA 173
Cdd:COG2956   176 DCARALLLLAELYLEQGDYEEAIAALERALEQ---------DPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDD 246

                         170       180
                  ....*....|....*....|....*..
gi 1907190984 174 STYsAIGYIHSLMGNFENAVDYFHTAL 200
Cdd:COG2956   247 LLL-ALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
141-205 1.64e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.55  E-value: 1.64e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 141 LLNNLGHVCRKLKKYAEALDYHRQALVLI--------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 205
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 72-170 1.71e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.74  E-value: 1.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  72 YGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAignevtvdkWEPLLNNLGHVCRK 151
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPD---------NPNAYSNLAALLLS 134

                          90
                  ....*....|....*....
gi 1907190984 152 LKKYAEALDYHRQALVLIP 170
Cdd:COG5010   135 LGQDDEAKAALQRALGTSP 153
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 103-216 2.69e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.81  E-value: 2.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 103 GVVAFQNGEWKTAEKWFLDALEKikaignevtVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 182
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALEL---------DPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1907190984 183 HSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 216
Cdd:COG4783    82 LLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 104-202 3.56e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 3.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 104 VVAFQNGEWKTAEKWFLDALEKikaignevtvDKWEP-LLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYI 182
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQL----------DPNNPeLYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131

                          90       100
                  ....*....|....*....|
gi 1907190984 183 HSLMGNFENAVDYFHTALGL 202
Cdd:COG5010   132 LLSLGQDDEAKAALQRALGT 151
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 148-214 9.94e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 9.94e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907190984 148 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 214
Cdd:COG5010    63 LYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLA 129
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 43-124 1.52e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.34  E-value: 1.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  43 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDA 122
Cdd:COG5010    69 DFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRA 148


                  ..
gi 1907190984 123 LE 124
Cdd:COG5010   149 LG 150
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 87-206 3.48e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  87 QALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNNLGHVCRKLKKYAEALDYHRQA 165
Cdd:COG4235     8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALR----------LDPDNAdALLDLAEALLAAGDTEEAEELLERA 77

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1907190984 166 LVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG4235    78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 30-124 4.06e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 4.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  30 AWIAYGHSFAVESEHDQAMAAYFTAAQLMKGchLPMLYIGL--EYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAF 107
Cdd:COG4235    19 GWLLLGRAYLRLGRYDEALAAYEKALRLDPD--NADALLDLaeALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                          90
                  ....*....|....*..
gi 1907190984 108 QNGEWKTAEKWFLDALE 124
Cdd:COG4235    97 QQGDYAEAIAAWQKLLA 113
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 35-202 6.50e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.85  E-value: 6.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  35 GHSFAVESEHDQAMAAYFTAAQLMKGCHLPMlYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKT 114
Cdd:TIGR02917 710 GDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDK 788

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 115 AEKWFLDALEKikAIGNEVTvdkweplLNNLGHVCRKLKKyAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVD 194
Cdd:TIGR02917 789 AIKHYQTVVKK--APDNAVV-------LNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALP 858


                  ....*...
gi 1907190984 195 YFHTALGL 202
Cdd:TIGR02917 859 LLRKAVNI 866
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 69-214 7.56e-07

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 49.26  E-value: 7.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  69 GLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALekikAIGNEVTvdkwePLLNNLG-H 147
Cdd:TIGR02521  38 ALGYLEQGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRAL----TLNPNNG-----DVLNNYGtF 108

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907190984 148 VCRKlKKYAEALDYHRQALV--LIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDdtFSVTMLG 214
Cdd:TIGR02521 109 LCQQ-GKYEQAMQQFEQAIEdpLYPQPARSLENAGLCALKAGDFDKAEKYLTRALQIDPQ--RPESLLE 174
TPR_12 pfam13424
Tetratricopeptide repeat;
100-166 1.30e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.46  E-value: 1.30e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907190984 100 HEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEpLLNNLGHVCRKLKKYAEALDYHRQAL 166
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTAT-TLLNLGRLYLELGRYEEALELLERAL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
141-209 2.02e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.99  E-value: 2.02e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 141 LLNNLGHVCRKLKKYAEAL-DYhRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 209
Cdd:COG4785    75 LYYERGVAYDSLGDYDLAIaDF-DQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYA 143
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 142-214 2.54e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 2.54e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 142 LNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 214
Cdd:COG4783     7 LYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLG 79
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 14-125 2.67e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 2.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG4783    24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP 103

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAEKWFLDALEK 125
Cdd:COG4783   104 EHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 62-216 3.12e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 3.12e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  62 HLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEdpfvIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPL 141
Cdd:COG3914     1 AAAAALLALAALAAAALLAAAAAAELALAAELE----AAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLL 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907190984 142 LNN----LGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHC 216
Cdd:COG3914    77 LAAllelAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEA 155
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 66-173 3.28e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.77  E-value: 3.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  66 LYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkikaignevtVDKWEP-LLNN 144
Cdd:COG4235    21 LLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA----------LDPDNPeALYL 90

                          90       100
                  ....*....|....*....|....*....
gi 1907190984 145 LGHVCRKLKKYAEALDYHRQALVLIPQNA 173
Cdd:COG4235    91 LGLAAFQQGDYAEAIAAWQKLLALLPADA 119
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
43-200 4.06e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.83  E-value: 4.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  43 EHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDA 122
Cdd:COG4785    88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907190984 123 LEKikaignevtvDKWEPLLNNLGHVCRKLKKYAEALDYHRQAlvlipqnastysaIGYIHSLMGNFENAVDYFHTAL 200
Cdd:COG4785   168 LEL----------DPNDPERALWLYLAERKLDPEKALALLLED-------------WATAYLLQGDTEEARELFKLAL 222
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 142-172 7.37e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 42.05  E-value: 7.37e-06
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907190984  142 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 172
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
142-172 9.97e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 41.64  E-value: 9.97e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1907190984 142 LNNLGHVCRKLKKYAEALDYHRQALVLIPQN 172
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 144-214 1.40e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 1.40e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907190984 144 NLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLG 214
Cdd:COG4235    22 LLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
148-215 1.43e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.85  E-value: 1.43e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907190984 148 VCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDyFHTALGLRRDDTFSVTMLGH 215
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAE 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 67-200 3.92e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 3.92e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  67 YIGLEYGLTNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALEkiKAIGNevtVDKWepllNNLG 146
Cdd:TIGR02917 130 LRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLT--ADPGN---VDAL----LLKG 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1907190984 147 HVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTAL 200
Cdd:TIGR02917 201 DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALL 254
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
33-206 4.42e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 4.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  33 AYGHSFAVESEHDQAMAAYFTAAQLMKGC-HLPMLYIGLE---YGLTNNSKLAERFFGQALSI-----APEDPFVIHEVG 103
Cdd:COG4785     1 LYALALALLLALALAAAAASKAAILLAALlFAAVLALAIAladLALALAAAALAAAALAAERIdralaLPDLAQLYYERG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 104 VVAFQNGEWKTAEKWFLDALEkIKAignevtvDKWEpLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIH 183
Cdd:COG4785    81 VAYDSLGDYDLAIADFDQALE-LDP-------DLAE-AYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIAL 151

                         170       180
                  ....*....|....*....|...
gi 1907190984 184 SLMGNFENAVDYFHTALGLRRDD 206
Cdd:COG4785   152 YYLGRYELAIADLEKALELDPND 174
COG3899 COG3899
Predicted ATPase [General function prediction only];
81-205 4.69e-05

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.23  E-value: 4.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984   81 AERFFGQALSIAPEDPFVIHEV------GVVAFQNGEWKTAEKWFLDALEK--IKAIGNEVTVDKWEPL--LNNLGHVCR 150
Cdd:COG3899    724 ALRYLERALELLPPDPEEEYRLalllelAEALYLAGRFEEAEALLERALAAraLAALAALRHGNPPASAraYANLGLLLL 803

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907190984  151 klKKYAEALDYHRQALVLI------PQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRD 205
Cdd:COG3899    804 --GDYEEAYEFGELALALAerlgdrRLEARALFNLGFILHWLGPLREALELLREALEAGLE 862
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 14-134 7.58e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 7.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG3914   132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAEKwFLDALEKIKAIGNEVT 134
Cdd:COG3914   212 DNADAHSNLLFALRQACDWEVYDR-FEELLAALARGPSELS 251
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
14-173 7.82e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.46  E-value: 7.82e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG0457    62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  94 EDPFVIHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNA 173
Cdd:COG0457   142 DDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAE 221
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 62-202 2.25e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  62 HLPMLYIG--LEYGLtNNSKLAERFFGQALSIAPEDPFVIHEVGVVAFQNGEwktaekwFLDALEKIKAIGNEVTVDKwe 139
Cdd:TIGR02917 294 YLPALLLAgaSEYQL-GNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGR-------VDEAIATLSPALGLDPDDP-- 363

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 140 PLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 202
Cdd:TIGR02917 364 AALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQL 426
TPR_11 pfam13414
TPR repeat;
146-187 2.26e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 38.22  E-value: 2.26e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1907190984 146 GHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMG 187
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_7 pfam13176
Tetratricopeptide repeat;
141-168 4.44e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 37.13  E-value: 4.44e-04
                          10        20
                  ....*....|....*....|....*...
gi 1907190984 141 LLNNLGHVCRKLKKYAEALDYHRQALVL 168
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALAL 28
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 14-93 5.81e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 5.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  14 IRVILKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFGQALSIAP 93
Cdd:COG5010    74 LALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 79-170 1.39e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.89  E-value: 1.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  79 KLAErffgQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDALekikAIGNEVTVDKWepllnnLGHVCRKLKKYAEA 158
Cdd:COG3071   245 KRAE----KWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEAAL----ALRPSAEAYAE------LARLLEQLGDPEEA 310

                          90
                  ....*....|..
gi 1907190984 159 LDYHRQALVLIP 170
Cdd:COG3071   311 AEHYRKALALAL 322
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 173-206 1.64e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 1.64e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1907190984  173 ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 206
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 155-209 1.72e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.53  E-value: 1.72e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1907190984 155 YAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFS 209
Cdd:cd24142    16 FELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYE 70
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 157-226 1.92e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 37.68  E-value: 1.92e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984 157 EALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHcIEMYIGDSEA 226
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAE-ALLAAGDTEE 69
TPR_1 pfam00515
Tetratricopeptide repeat;
173-206 2.11e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 2.11e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1907190984 173 ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDD 206
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
142-166 2.28e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 35.17  E-value: 2.28e-03
                          10        20
                  ....*....|....*....|....*
gi 1907190984 142 LNNLGHVCRKLKKYAEALDYHRQAL 166
Cdd:pfam13374   5 LNNLANALRAQGRYDEAEELLEEAL 29
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 155-202 3.41e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 37.73  E-value: 3.41e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1907190984 155 YAEALDYHRQALVLiPQNASTYSAI----GYIHSLMGNFENAVDYFHTALGL 202
Cdd:PRK02603   51 YAEALENYEEALKL-EEDPNDRSYIlynmGIIYASNGEHDKALEYYHQALEL 101
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 81-213 7.18e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.14  E-value: 7.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907190984  81 AERFFGQALSIAPEDPFVIHEVGVVAFQNGEWKTAEKWFLDAlekIKAIGNEVTVDkwepLLNNLGHVcrKLKKYAEALD 160
Cdd:TIGR02917 382 AAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETA---AQLDPELGRAD----LLLILSYL--RSGQFDKALA 452

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1907190984 161 YHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTML 213
Cdd:TIGR02917 453 AAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANL 505
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH