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Conserved domains on  [gi|1907199001|ref|XP_036011005|]
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golgin subfamily A member 4 isoform X17 [Mus musculus]

Protein Classification

GRIP and coiled-coil domain-containing protein; GRIP and coiled-coil domain-containing protein; GRIP domain-containing protein; GRIP domain-containing protein( domain architecture ID 13528997)

GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP (golgin-97, RanBP2alpha, Imh1p and p230/golgin-245) domain-containing protein; similar to Eremothecium gossypii golgin IMH1 which is involved in vesicular transport between an endosomal compartment and the Golgi apparatus; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure; GRIP domain-containing protein; GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 376-964 1.74e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.74e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  376 EDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 454
Cdd:COG1196    192 EDILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  455 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 534
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  535 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 614
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  615 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 691
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  692 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 769
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  770 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 849
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  850 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 929
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199001  930 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 964
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 675-1281 2.04e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 2.04e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 752
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  753 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 832
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  833 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 912
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 991
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  992 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1067
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1068 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1147
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1148 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1227
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1228 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1281
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1001-1695 2.04e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1001 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1075
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1076 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1155
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1156 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1235
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1236 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1311
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1312 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1381
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1382 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1437
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1438 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1501
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1502 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1568
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1569 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1648
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199001 1649 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1471-2139 2.25e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.25e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1471 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1550
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1551 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1630
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1631 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1710
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1711 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1787
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1788 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1840
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1841 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1903
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1904 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1983
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1984 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2063
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2064 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2138
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199001 2139 A 2139
Cdd:TIGR02168  910 R 910
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2164-2207 3.59e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.59e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199001  2164 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2207
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 132-534 6.48e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  132 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 208
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  209 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 288
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  289 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELhmaeKTKLITQLRDAKNLIEQLEQDKGMVITETKRQM 368
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIL----KDKKDAKIRELEARVSDLELEKVKLVNAGSERL 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  369 LETLELKED------EIAQLRSHIKQMTTQGEELR-------EQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQ-RR 434
Cdd:pfam15921  646 RAVKDIKQErdqllnEVKTSRNELNSLSEDYEVLKrnfrnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDgHA 725

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  435 MKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKlHAEELASKEQELSRRLE---ARERELQE 511
Cdd:pfam15921  726 MKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQ-ELSTVATEKNKMAGELEvlrSQERRLKE 804

                          410       420
                   ....*....|....*....|....*....
gi 1907199001  512 Q---MRIALEKSRSEYLK---LTQEKEQQ 534
Cdd:pfam15921  805 KvanMEVALDKASLQFAEcqdIIQRQEQE 833
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 376-964 1.74e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.74e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  376 EDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 454
Cdd:COG1196    192 EDILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  455 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 534
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  535 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 614
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  615 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 691
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  692 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 769
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  770 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 849
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  850 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 929
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199001  930 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 964
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 675-1281 2.04e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 2.04e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 752
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  753 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 832
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  833 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 912
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 991
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  992 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1067
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1068 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1147
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1148 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1227
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1228 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1281
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 675-1381 3.05e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.05e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 754
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 833
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  834 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 906
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  907 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 983
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  984 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1054
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1055 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1110
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1111 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1183
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1184 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1253
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1254 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1333
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199001 1334 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1381
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 363-1158 1.67e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  363 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDwaFEELEKALSTAQKTEDAQRRMKMEMDEQ 442
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  443 MKAVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsr 521
Cdd:TIGR02168  250 EAEEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ-- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  522 SEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKN 601
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  602 KHNKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKL 681
Cdd:TIGR02168  397 SLNNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  682 DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ-------- 744
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegye 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  745 -----------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE--- 794
Cdd:TIGR02168  537 aaieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrk 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  795 --------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhv 854
Cdd:TIGR02168  617 alsyllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE------ 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  855 cEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEE 934
Cdd:TIGR02168  691 -EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  935 SIsilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDT 1014
Cdd:TIGR02168  769 RL----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1015 VSRLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1091
Cdd:TIGR02168  840 LEDLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001 1092 ARLKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1158
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
PTZ00121 PTZ00121
MAEBL; Provisional
 310-1077 3.97e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.58  E-value: 3.97e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  310 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLR---DAKNLIEQLEQDKGMVITETKRQMletlELKEDEIAQLRSHI 386
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARkaeDAKRVEIARKAEDARKAEEARKAE----DAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  387 KQMTT--QGEELR--------EQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLR 456
Cdd:PTZ00121  1188 RKAEElrKAEDARkaeaarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR 1267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  457 LQHELSRVRQEAASMAKKNSEEQVA-----ALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEK 531
Cdd:PTZ00121  1268 RQAAIKAEEARKADELKKAEEKKKAdeakkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  532 EQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETS--LEKSLQESKTQSEHLAVHLE-----------A 598
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAAAakkkadeakkkA 1427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  599 EKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAvEELREKYQQEKDA-LLKEKESLFQAHIQDMNEKT 677
Cdd:PTZ00121  1428 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA-DEAKKKAEEAKKAdEAKKKAEEAKKKADEAKKAA 1506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  678 LEKL---DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQrEVGSISEQQELTVRRAEK 754
Cdd:PTZ00121  1507 EAKKkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRKAEE 1585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRE-----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQK 829
Cdd:PTZ00121  1586 AKKAEEARIEEVMKLYEEEKKMkaeeaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  830 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKEN 909
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  910 I-ILQMREEQAKEIEILKQTLSSKEESISI---------LHEEYETKFKNQEKRMEKIKQKAKEMQE----------TKK 969
Cdd:PTZ00121  1746 AeEAKKDEEEKKKIAHLKKEEEKKAEEIRKekeavieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlvinDSK 1825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  970 KLLDQEAKLKKELENTVLELSQKEKQ--FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDV-IEAWEK 1046
Cdd:PTZ00121  1826 EMEDSAIKEVADSKNMQLEEADAFEKhkFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIeREIPNN 1905

                          810       820       830
                   ....*....|....*....|....*....|.
gi 1907199001 1047 KLSQQAAELRDKHAEQMEEKEQGLGELRQKV 1077
Cdd:PTZ00121  1906 NMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 557-1197 3.42e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 79.01  E-value: 3.42e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  557 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 636
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  637 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 714
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  715 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 793
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  794 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 873
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  874 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 945
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1013
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1014 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1093
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1094 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1144
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199001 1145 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1197
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1001-1695 2.04e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1001 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1075
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1076 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1155
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1156 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1235
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1236 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1311
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1312 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1381
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1382 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1437
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1438 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1501
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1502 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1568
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1569 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1648
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199001 1649 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1471-2139 2.25e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.25e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1471 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1550
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1551 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1630
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1631 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1710
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1711 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1787
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1788 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1840
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1841 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1903
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1904 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1983
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1984 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2063
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2064 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2138
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199001 2139 A 2139
Cdd:TIGR02168  910 R 910
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1832-2136 2.89e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 2.89e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1832 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1911
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1912 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 1991
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1992 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2071
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001 2072 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2136
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 1422-2138 4.86e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1422 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1500
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1501 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1579
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1580 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1655
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1656 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1735
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1736 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1815
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1816 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1895
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1896 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1974
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1975 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2049
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2050 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2122
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907199001 2123 EQVHNLEDRLKRYEKN 2138
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1267-1695 1.36e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1267 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1336
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1337 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1412
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1413 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1488
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1489 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1557
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1558 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1627
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1628 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
975-1379 1.52e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  975 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1054
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1055 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1134
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1135 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1201
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1202 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1247
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1248 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1327
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1328 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1379
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2164-2207 3.59e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.59e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199001  2164 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2207
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1167-1695 1.87e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1167 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1237
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1238 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1317
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1318 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1397
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1398 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1477
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1478 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1554
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1555 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1629
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1630 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1297-2092 2.86e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1297 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1372
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1373 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1452
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1453 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1532
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1533 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1612
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1613 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1692
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1693 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1770
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1771 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1850
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1851 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1930
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1931 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 2010
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2011 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2090
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907199001 2091 TK 2092
Cdd:pfam02463  962 NK 963
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 652-1684 5.38e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 5.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  652 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 731
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  732 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 811
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  812 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 891
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  892 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 971
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  972 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLE---------ENQRQQIESLTGA 1032
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1033 HQRKLDDV------IEAWEKKLSQQAAELRDKHAE---QMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDV 1103
Cdd:pfam01576  389 LQAELRTLqqakqdSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1104 ALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1183
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1184 SCKSLHELSKKSLEDKSLNLKSL----------LEELASQLDSRCERTKAL---------LEAKTNELVCTSRDKADAIL 1244
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLektknrlqqeLDDLLVDLDHQRQLVSNLekkqkkfdqMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1245 ARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEG 1324
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1325 GQQRQAASEKESCITQLKKELAENINAvtllREELSEKKSEiaSLSKQLSDLGAQLESsiSPSDKAEAISALSKqheeqe 1404
Cdd:pfam01576  709 QATEDAKLRLEVNMQALKAQFERDLQA----RDEQGEEKRR--QLVKQVRELEAELED--ERKQRAQAVAAKKK------ 774

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1405 lqLQAQLQELSLKVDALSKEKMSALEQVdhwsnkfsewkKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEE-------Q 1477
Cdd:pfam01576  775 --LELDLKELEAQIDAANKGREEAVKQL-----------KKLQAQMKDLQRELEEARASRDEILAQSKESEKklknleaE 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1478 ICLLKEDL---DRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT 1554
Cdd:pfam01576  842 LLQLQEDLaasERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1555 EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREhvssleaELGTVKKELEhvnSSVKSRDGELKALEDKLELES---A 1631
Cdd:pfam01576  922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQE-------MEGTVKSKFK---SSIAALEAKIAQLEEQLEQESrerQ 991

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 1632 AKVELKRKAEQKIaairKQLLSQME------EKTQRYAKDTENRLSELSAQLKEREKQV 1684
Cdd:pfam01576  992 AANKLVRRTEKKL----KEVLLQVEderrhaDQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2165-2204 1.60e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.60e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907199001 2165 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2204
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1440-2137 7.23e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 7.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1440 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1519
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1520 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1599
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1600 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1677
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1678 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1752
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1753 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVsqPMGEETGNNTGVKQNWASVVDSVQ 1832
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV--ENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1833 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYE-KSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNV 1911
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1912 GTVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 1989
Cdd:pfam02463  643 AKESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1990 LMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTD 2069
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 2070 LQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2137
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 584-828 2.10e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  584 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 660
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  661 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 736
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  737 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 816
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907199001  817 GAyEEQLAQMQQ 828
Cdd:NF012221  1757 AA-ENKANQAQA 1767
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1915-2025 5.99e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 5.99e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  1915 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 1987
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907199001  1988 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2025
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 132-534 6.48e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  132 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 208
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  209 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 288
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  289 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELhmaeKTKLITQLRDAKNLIEQLEQDKGMVITETKRQM 368
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIL----KDKKDAKIRELEARVSDLELEKVKLVNAGSERL 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  369 LETLELKED------EIAQLRSHIKQMTTQGEELR-------EQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQ-RR 434
Cdd:pfam15921  646 RAVKDIKQErdqllnEVKTSRNELNSLSEDYEVLKrnfrnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDgHA 725

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  435 MKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKlHAEELASKEQELSRRLE---ARERELQE 511
Cdd:pfam15921  726 MKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQ-ELSTVATEKNKMAGELEvlrSQERRLKE 804

                          410       420
                   ....*....|....*....|....*....
gi 1907199001  512 Q---MRIALEKSRSEYLK---LTQEKEQQ 534
Cdd:pfam15921  805 KvanMEVALDKASLQFAEcqdIIQRQEQE 833
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 131-454 8.83e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 8.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  131 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREkkklQGILSQSQDKSLRRISELREELQMDQQ---AKKHLQDEFD 207
Cdd:TIGR02169  689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE----IEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELE 764

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  208 ACLEEKDQYISVLQTQVSLLKQRLQNGPMnvdaPKPLPPGELQAEVHGDTEKMEGVGEPVGGGTSAKtLEMLQQRVKRQE 287
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALNDLEARLSHSRI----PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE-KEYLEKEIQELQ 839

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  288 NLLQRCKETIGSHKEQCALLLSEKEALQE----------QLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDK 357
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEeleeleaalrDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  358 GmvitetkrQMLETLELKEDEIAQLRSHIKQMTTQ-GEELREQKEKSERAALYEQDWAFEELEkaLSTAQKTEDAQRRMK 436
Cdd:TIGR02169  920 S--------ELKAKLEALEEELSEIEDPKGEDEEIpEEELSLEDVQAELQRVEEEIRALEPVN--MLAIQEYEEVLKRLD 989

                          330
                   ....*....|....*....
gi 1907199001  437 MEMDEQMK-AVERASEEER 454
Cdd:TIGR02169  990 ELKEKRAKlEEERKAILER 1008
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 376-964 1.74e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 109.26  E-value: 1.74e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  376 EDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 454
Cdd:COG1196    192 EDILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  455 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 534
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  535 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 614
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  615 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 691
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  692 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 769
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  770 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 849
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  850 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 929
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199001  930 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 964
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 675-1281 2.04e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.77  E-value: 2.04e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEalrardqLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRA 752
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGE-------LERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAE 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  753 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLD 832
Cdd:COG1196    248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  833 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIIL 912
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQ 991
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEEL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  992 KEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKE 1067
Cdd:COG1196    487 AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1068 QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEK 1147
Cdd:COG1196    567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRA 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1148 LSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEA 1227
Cdd:COG1196    640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE 719

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1228 KTNELV--CTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEE 1281
Cdd:COG1196    720 ELEEEAleEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 675-1381 3.05e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.52  E-value: 3.05e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 754
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 833
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  834 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 906
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  907 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 983
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  984 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 1054
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1055 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 1110
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1111 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1183
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1184 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1253
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1254 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1333
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199001 1334 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1381
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 552-1389 1.89e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 1.89e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  552 ESENKLQElgqeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA---EQHRTEVEGLQQQQDSL 628
Cdd:TIGR02168  176 ETERKLER----TRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVlrlEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  629 WTER--LQSLSQQHQAAVEELReKYQQEKDALLKEKESLFQAHIQDMNEKTL------EKLDKKQMELESVSSELSEALR 700
Cdd:TIGR02168  252 EEELeeLTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEISRLEQqkqilrERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  701 ARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREVGSISEQQELTV--RRAEKALKDELSRLGALLDERDEHLRERQ 778
Cdd:TIGR02168  331 KLDELAEEL-----------AELEEKLEELKEELESLEAELEELEAELEelESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  779 ARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR-----EQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKH 853
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  854 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNS----------TVEKEQARQ---SLMEKENIILQMREEQAK 920
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlseliSVDEGYEAAieaALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  921 E-IEILKQTLSSKE---ESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL----------------LDQEAKLKK 980
Cdd:TIGR02168  560 KaIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  981 ELENTVLELSQKEKQFNAQILeMAQANSAGISDTVSRLEE--NQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAAELRDK 1058
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGV-ITGGSAKTNSSILERRREieELEEKIEELEEK-IAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1059 HAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 1138
Cdd:TIGR02168  718 RKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1139 DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhELSKKSLEDKSLNLKSLLEELASqldsrc 1218
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL-------EDLEEQIEELSEDIESLAAEIEE------ 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1219 ertkalLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEE 1298
Cdd:TIGR02168  864 ------LEELIEEL----ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1299 KEKQIKTMKADI--EGLLTEKEALQQEGGQQRQAASEKEScITQLKKELAE----NINAVtllrEELSEKKSEIASLSKQ 1372
Cdd:TIGR02168  934 LEVRIDNLQERLseEYSLTLEEAEALENKIEDDEEEARRR-LKRLENKIKElgpvNLAAI----EEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|
gi 1907199001 1373 LSDLG---AQLESSISPSDK 1389
Cdd:TIGR02168 1009 KEDLTeakETLEEAIEEIDR 1028
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 438-1030 3.08e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 3.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  438 EMDEQMKAVERASE--EERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLhAEELASKEQELSRRLEARERELQE---- 511
Cdd:COG1196    197 ELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEElrle 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  512 --QMRIALEKSRSEYLKLTQEKEQ--QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKT 587
Cdd:COG1196    276 leELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  588 QSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLfq 667
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  668 ahiqdmnektLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRRHHQREVGSISEQQEL 747
Cdd:COG1196    434 ----------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  748 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 827
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  828 QKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 907
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  908 ENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL 987
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907199001  988 ELSQKEKQFNAQILEMAQANSAGISDtvsrlEENQRQQIESLT 1030
Cdd:COG1196    736 ELLEELLEEEELLEEEALEELPEPPD-----LEELERELERLE 773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 302-882 8.23e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 90.77  E-value: 8.23e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  302 EQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKgMVITETKRQMLETLELKEDEIAQ 381
Cdd:COG1196    249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI-ARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  382 LRSHIKQMTTQGEELREQKEKSErAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHEL 461
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAE-EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  462 SRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEE 541
Cdd:COG1196    407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE-EEALLELLAELLEEAALLEAALAELLEE 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  542 LELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAeknkhnkELTALAEQHRTEVEGL 621
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA-------ALAAALQNIVVEDDEV 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  622 QQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRA 701
Cdd:COG1196    559 AAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  702 RDQLAEELSVLRGDADkmkqaLEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 781
Cdd:COG1196    639 AVTLAGRLREVTLEGE-----GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  782 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEThkkhV----CEE 857
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGP----VnllaIEE 789

                          570       580
                   ....*....|....*....|....*
gi 1907199001  858 LDAQRAQVQQLERQRSELEEKVRSL 882
Cdd:COG1196    790 YEELEERYDFLSEQREDLEEARETL 814
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 363-1158 1.67e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 1.67e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  363 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDwaFEELEKALSTAQKTEDAQRRMKMEMDEQ 442
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  443 MKAVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsr 521
Cdd:TIGR02168  250 EAEEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ-- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  522 SEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKN 601
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  602 KHNKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKL 681
Cdd:TIGR02168  397 SLNNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  682 DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR-----HHQRE----VGSISEQ-------- 744
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvkallKNQSGlsgiLGVLSELisvdegye 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  745 -----------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE--- 794
Cdd:TIGR02168  537 aaieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrk 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  795 --------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhv 854
Cdd:TIGR02168  617 alsyllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE------ 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  855 cEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEE 934
Cdd:TIGR02168  691 -EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  935 SIsilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDT 1014
Cdd:TIGR02168  769 RL----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERR 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1015 VSRLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1091
Cdd:TIGR02168  840 LEDLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001 1092 ARLKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 1158
Cdd:TIGR02168  918 EELREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 743-1689 2.00e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 2.00e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  743 EQQELTVRRAEKALKDeLSRLGALLDERDEHLR--ERQARVQDLEAHLQKSAGELQQALAKLDLLhseqsAAREQAGAYE 820
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKslERQAEKAERYKELKAELRELELALLVLRLE-----ELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  821 EQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQA 900
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  901 RQSLMEKENIILQMREEQAKEIEILKQTLsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 980
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  981 ELENTVLELSQKEkqfnaqilEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKkLSQQAAELRdkha 1060
Cdd:TIGR02168  401 EIERLEARLERLE--------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER-LEEALEELR---- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1061 EQMEEKEQGLGELRQKVRIVQSEKEELtkevARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSER---ESQLQSQVEK-L 1136
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAaL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1137 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG----QVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAS 1212
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1213 QLdsrcertkalleaktneLVCTSRDKADAILARLSQCQRHTATVGEaLLRRMGQVSELEAQLTQLTEEQRtlkssfqqv 1292
Cdd:TIGR02168  624 GV-----------------LVVDDLDNALELAKKLRPGYRIVTLDGD-LVRPGGVITGGSAKTNSSILERR--------- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1293 tNQLEEKEKQIKTMKADIEGLLTEKEALqqeggqqRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1372
Cdd:TIGR02168  677 -REIEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1373 LSDLGAQLEssispsdKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1452
Cdd:TIGR02168  749 IAQLSKELT-------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1453 HQSTIKDLQAQLDVKATDAREKEEQICLLKEDLdrqnkkfECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEdcvt 1532
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERASLEEALA---- 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1533 QRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLeaelgtVKKELEHVNSSV 1612
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE------YSLTLEEAEALE 960

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001 1613 KSRDGELKALEDKLelesaakvelkRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLED 1689
Cdd:TIGR02168  961 NKIEDDEEEARRRL-----------KRLENKIKELGPVNLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEE 1021
PTZ00121 PTZ00121
MAEBL; Provisional
 310-1077 3.97e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.58  E-value: 3.97e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  310 EKEALQEQLDERLQELEKMKELHMAEKTKLITQLR---DAKNLIEQLEQDKGMVITETKRQMletlELKEDEIAQLRSHI 386
Cdd:PTZ00121  1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARkaeDAKRVEIARKAEDARKAEEARKAE----DAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  387 KQMTT--QGEELR--------EQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLR 456
Cdd:PTZ00121  1188 RKAEElrKAEDARkaeaarkaEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR 1267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  457 LQHELSRVRQEAASMAKKNSEEQVA-----ALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEK 531
Cdd:PTZ00121  1268 RQAAIKAEEARKADELKKAEEKKKAdeakkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  532 EQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETS--LEKSLQESKTQSEHLAVHLE-----------A 598
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdeAKKKAEEDKKKADELKKAAAakkkadeakkkA 1427

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  599 EKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAvEELREKYQQEKDA-LLKEKESLFQAHIQDMNEKT 677
Cdd:PTZ00121  1428 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA-DEAKKKAEEAKKAdEAKKKAEEAKKKADEAKKAA 1506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  678 LEKL---DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQrEVGSISEQQELTVRRAEK 754
Cdd:PTZ00121  1507 EAKKkadEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAE-EAKKAEEDKNMALRKAEE 1585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRE-----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQK 829
Cdd:PTZ00121  1586 AKKAEEARIEEVMKLYEEEKKMkaeeaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  830 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKEN 909
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  910 I-ILQMREEQAKEIEILKQTLSSKEESISI---------LHEEYETKFKNQEKRMEKIKQKAKEMQE----------TKK 969
Cdd:PTZ00121  1746 AeEAKKDEEEKKKIAHLKKEEEKKAEEIRKekeavieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlvinDSK 1825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  970 KLLDQEAKLKKELENTVLELSQKEKQ--FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDV-IEAWEK 1046
Cdd:PTZ00121  1826 EMEDSAIKEVADSKNMQLEEADAFEKhkFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIeREIPNN 1905

                          810       820       830
                   ....*....|....*....|....*....|.
gi 1907199001 1047 KLSQQAAELRDKHAEQMEEKEQGLGELRQKV 1077
Cdd:PTZ00121  1906 NMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 273-852 4.49e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.99  E-value: 4.49e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  273 AKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQ 352
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  353 LEQDKGMVITETKRqmLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQ 432
Cdd:COG1196    325 LAELEEELEELEEE--LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  433 RRMKMEMDEQMKAVERAsEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQ 512
Cdd:COG1196    403 EELEEAEEALLERLERL-EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  513 MRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHL 592
Cdd:COG1196    482 LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAA 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  593 AVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQD 672
Cdd:COG1196    562 AIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVT 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  673 MNEKTLEKL-------DKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVgsISEQQ 745
Cdd:COG1196    642 LAGRLREVTlegeggsAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE--ERLEE 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  746 ELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQ 825
Cdd:COG1196    720 ELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEEYEELEERYDF 799

                          570       580
                   ....*....|....*....|....*..
gi 1907199001  826 MQQKVLDLETEKSLLTKQVVEMETHKK 852
Cdd:COG1196    800 LSEQREDLEEARETLEEAIEEIDRETR 826
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 862-1694 8.22e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.34  E-value: 8.22e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  862 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQaKEIEILKQTLSSKEESISILHE 941
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  942 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagisdtvsrleen 1021
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1022 QRQQIESLTGAHQRKLDDVIEAWEKklsQQAAELRdkhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQ 1101
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELEAE---LEELESR------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1102 DVALAGLQGQLEQKSAVIVSLSEREsqLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKE 1181
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1182 LQSCKSLHEL------SKKSLEDKSLNLKSLLEELASQLDSRCERTKAL---LEAKTNELVCTSRDKADAILARLSQCQR 1252
Cdd:TIGR02168  491 LDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVDEGYEAAIeaaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1253 HTATVGEAllrrmgqVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ--- 1329
Cdd:TIGR02168  571 GRVTFLPL-------DSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1330 --------------------AASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDK 1389
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1390 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKAT 1469
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1470 DAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYN 1549
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1550 QQRdtehsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgelkaledklele 1629
Cdd:TIGR02168  884 SLE--------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----------------------- 932

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001 1630 saakvelkrKAEQKIAairkQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNL 1694
Cdd:TIGR02168  933 ---------GLEVRID----NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 139-988 3.54e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 3.54e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  139 LRRMERSLSSYRgKYSELVTAFQTLQREKKKLQGILS----QSQDKSLRRISELREELQMDQQAKKHLQDEFDACLEEKD 214
Cdd:TIGR02168  195 LNELERQLKSLE-RQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTAELQELEEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  215 QYISVLQTQVSLLKQRLQNgpmnvdapkplppgeLQAEVHG-DTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRC 293
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYA---------------LANEISRlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  294 KETIgshKEQCALLLSEKEALQEQLDERLQELEKMKElHMAEKTKLITQLRDAKNLIEQLEQdkgmVITETKRQMLETLE 373
Cdd:TIGR02168  339 LAEL---EEKLEELKEELESLEAELEELEAELEELES-RLEELEEQLETLRSKVAQLELQIA----SLNNEIERLEARLE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  374 LKEDEIAQLRshikqmttqgEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEE 453
Cdd:TIGR02168  411 RLEDRRERLQ----------QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  454 RLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARErELQEQMRIALEKSRSEYLKLTQEKEQ 533
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE-GYEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  534 QESLALEELELQKKAIL-------TESENKLQELGQEAEAYRTRILELETSLEK----------------SLQE-----S 585
Cdd:TIGR02168  560 KAIAFLKQNELGRVTFLpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNalelaK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  586 KTQSEHLAVHLEAEK-------NKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDAL 658
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLvrpggviTGGSAKTNSSILERRREIEELEEKIEEL-EEKIAELEKALAELRKELEELEEELEQLR 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  659 LKEKESLFQAHIQDMNEKTLEKldkkqmELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREV 738
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEA------EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQI 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  739 GSISEQQElTVRRAEKALKDELSRLGALLDErdehLRERQARVQDLEAHLQKSAGELQQALAKLdllhseqsaaREQAGA 818
Cdd:TIGR02168  792 EQLKEELK-ALREALDELRAELTLLNEEAAN----LRERLESLERRIAATERRLEDLEEQIEEL----------SEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  819 YEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNS--TV 895
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrEKLAQLELRLEglEV 936

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  896 EKEQARQSLMEKENIILQMREEQAKEIEI----LKQTLSSKEESISILHE---EYETKFKNQEKRMEKIKQKAKEMQETK 968
Cdd:TIGR02168  937 RIDNLQERLSEEYSLTLEEAEALENKIEDdeeeARRRLKRLENKIKELGPvnlAAIEEYEELKERYDFLTAQKEDLTEAK 1016

                          890       900
                   ....*....|....*....|
gi 1907199001  969 KKLLDQEAKLKKELENTVLE 988
Cdd:TIGR02168 1017 ETLEEAIEEIDREARERFKD 1036
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 372-1099 1.30e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.10  E-value: 1.30e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  372 LELKEDEIAQLRSHIKQMTTQGEELREQKEKSE------RAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKA 445
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEekleelRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  446 VER---ASEEERLRLQHELSRVRQEAASMAKKNSE--EQVAALQKLHaEELASKEQELSRRLEARERELQE------QMR 514
Cdd:TIGR02168  314 LERqleELEAQLEELESKLDELAEELAELEEKLEElkEELESLEAEL-EELEAELEELESRLEELEEQLETlrskvaQLE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  515 IALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE------KSLQESKTQ 588
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELErleealEELREELEE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  589 SEHLAVHLEAEKNKHNKELTALaEQHRTEVEGLQQQQDSLWTERLQsLSQQHQAAVE--ELREKYQQEKDALLKE----- 661
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG-LSGILGVLSEliSVDEGYEAAIEAALGGrlqav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  662 ----------------KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGD-------ADK 718
Cdd:TIGR02168  551 vvenlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  719 MKQALEaeleeQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALldERDEHLRERQARVQDLEAHLQKSAGELQQA 798
Cdd:TIGR02168  631 LDNALE-----LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  799 LAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK 878
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  879 VRSLAQLQDSQLKNSTVEKEQ-------------ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYEt 945
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREAldelraeltllneEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE- 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 kfkNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNA--QILEMAQANSAGISDTVSRLEENQR 1023
Cdd:TIGR02168  863 ---ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSElrRELEELREKLAQLELRLEGLEVRID 939

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1024 QQIESLTGAHQRKLDDVIEAWEKKLSQQaAELRDKhAEQMEEKEQGLG-----------ELRQKVRIVQSEKEELTKEVA 1092
Cdd:TIGR02168  940 NLQERLSEEYSLTLEEAEALENKIEDDE-EEARRR-LKRLENKIKELGpvnlaaieeyeELKERYDFLTAQKEDLTEAKE 1017


                   ....*..
gi 1907199001 1093 RLKEAVS 1099
Cdd:TIGR02168 1018 TLEEAIE 1024
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 363-1198 2.08e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.73  E-value: 2.08e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  363 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER---AALYEQDWAFEELEKALSTAQKTEDAQRRMKMEM 439
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqaLLKEKREYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  440 DEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA-----EELASKEQELSRRLEARERELQE-QM 513
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEleaeiASLERSIAEKERELEDAEERLAKlEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  514 RIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESKTQSEHLA 593
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  594 VHLEAEKnkhnKELTALAEQHRTEVEGLQQQQDSLWTERLQSlsqqhQAAVEELREKYQQEKDALLKEKESLFQahiqdm 673
Cdd:TIGR02169  409 DRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQELYD------ 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  674 nekTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRR--HHQ-REVGSISEQQELTVR 750
Cdd:TIGR02169  474 ---LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGR--------AVEEVLKASIQgvHGTvAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  751 RAEKAlkdelsRLGALLDERD-------EHLRERQA-----------RVQDLEAHLQKSAGELQQALAKLD--------- 803
Cdd:TIGR02169  543 VAAGN------RLNNVVVEDDavakeaiELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEfdpkyepaf 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  804 -------LLHSEQSAAREQAGAYeeQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELE 876
Cdd:TIGR02169  617 kyvfgdtLVVEDIEAARRLMGKY--RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  877 EKVRSlaqlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQtlssKEESISILHEEYEtkfkNQEKRMEK 956
Cdd:TIGR02169  695 SELRR----IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE----LEEDLSSLEQEIE----NVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  957 IKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqILEMAQANSAGISDTVSRLEENQrQQIESLTGAHQRK 1036
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1037 LDDVIEAWEKKLSQQAAELRDKhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKS 1116
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLN--GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1117 AVIVSLSERESQLQSQVEKLEADLGCSLSE----------KLSLQEELAELKLLADKSQLRVSELTgQVQAAEKELQSCK 1186
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKR 995

                          890
                   ....*....|..
gi 1907199001 1187 SLHELSKKSLED 1198
Cdd:TIGR02169  996 AKLEEERKAILE 1007
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 557-1197 3.42e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 79.01  E-value: 3.42e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  557 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 636
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  637 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 714
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  715 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 793
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  794 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 873
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  874 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 945
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 1013
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1014 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 1093
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1094 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 1144
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199001 1145 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 1197
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1001-1695 2.04e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.25  E-value: 2.04e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1001 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 1075
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1076 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 1155
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1156 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1235
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1236 SRDKAD----AILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1311
Cdd:TIGR02168  420 QQEIEEllkkLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1312 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1381
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1382 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1437
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1438 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1501
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1502 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1568
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1569 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1648
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199001 1649 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 844-1695 2.13e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 2.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  844 VVEMETHKKHVCEELDAQRaqvQQLERQRSELEEKVRSLAQLQDsqlknstvEKEQARQSLmekeniILQMREEQAKEIE 923
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLRR--------EREKAERYQ------ALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  924 ILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQIlEM 1003
Cdd:TIGR02169  228 LLKE-KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI-AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1004 AQANSAGISDTVSRLEENQRQQIESLtgahqRKLDDVIEAWEKKLSQQAAElRDKHAEQMEEKEQGLGELRQKVRIVQSE 1083
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEI-----DKLLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1084 KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEElaelklladk 1163
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1164 sqlrVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsRDKADAI 1243
Cdd:TIGR02169  450 ----IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL--KASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1244 LARLSQC----QRHTATVGEALLRRMGQV----SELEAQLTQLTEEQRTLKSSFQQVTN-QLEEKEKQIKTMKADIE--- 1311
Cdd:TIGR02169  524 HGTVAQLgsvgERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfav 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1312 --------------------GLLTEKEALQQEGGQQRQAA-----SEKESCITQLKKELAENINAVTLLREELSEKKSEI 1366
Cdd:TIGR02169  604 dlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRMVTlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1367 ASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKA 1446
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1447 QSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVV 1525
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1526 ELEDCVTQRKKEVESLN----------ETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1595
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNgkkeeleeelEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1596 AELGTVKKELEHVNSSVKSrdgelkALEDKLELESAAKVELKRKA-EQKIAAIRKQLLSQMEEktqryAKDTENRLSELS 1674
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGE------DEEIPEEELSLEDVQAELQRvEEEIRALEPVNMLAIQE-----YEEVLKRLDELK 992

                          890       900
                   ....*....|....*....|.
gi 1907199001 1675 AQLKEREKQVHSLEDKLKNLE 1695
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYE 1013
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1471-2139 2.25e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.25e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1471 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1550
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1551 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1630
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1631 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1710
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1711 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1787
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1788 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1840
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1841 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1903
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1904 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1983
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1984 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 2063
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2064 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2138
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199001 2139 A 2139
Cdd:TIGR02168  910 R 910
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 131-875 2.61e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.61e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  131 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslRRISELREELQMDQQAKKHLQDEF---D 207
Cdd:TIGR02168  247 ELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA----NEISRLEQQKQILRERLANLERQLeelE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  208 ACLEEKDQYISVLQTQVSLLKQRLQngpmnvdapkplppgELQAEVHGDTEKMEGVGEPVGGGTSAktLEMLQQRVKRQE 287
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLE---------------ELKEELESLEAELEELEAELEELESR--LEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  288 NLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKM-KELHMAEKTKLITQLRDAKNLIEQLEQDKGMVIT--ET 364
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEalEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  365 KRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAF----------------EELEKALSTAQKt 428
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdEGYEAAIEAALG- 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  429 EDAQRRMKMEMDEQMKAVERASEEERLRLQH-ELSRVRQ---EAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLE- 503
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQNELGRVTFlPLDSIKGteiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  504 -ARERELQEQMRIAlEKSRSEYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE-- 579
Cdd:TIGR02168  625 vLVVDDLDNALELA-KKLRPGYRIVTLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAel 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  580 KSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQslSQQHQAAVEELREKYQQEKDALL 659
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAE 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  660 KEKESLfQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVG 739
Cdd:TIGR02168  782 AEIEEL-EAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  740 SISEQQEltvrrAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAY 819
Cdd:TIGR02168  860 EIEELEE-----LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001  820 EEQLAQMQQKVldleTEKSLLTKQvvEMETHKKHVCEELDAQRAQVQQLERQRSEL 875
Cdd:TIGR02168  935 EVRIDNLQERL----SEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 380-1103 3.10e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.48  E-value: 3.10e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  380 AQLRSHIKQMTTQGEELRE----QKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL 455
Cdd:PTZ00121  1060 AEAKAHVGQDEGLKPSYKDfdfdAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDA 1139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  456 RLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEElASKEQELSRRLEARE----RELQEQMRIALEKSRSEYLKLTQEK 531
Cdd:PTZ00121  1140 RKAEEARKAEDAKRVEIARKAEDARKAEEARKAED-AKKAEAARKAEEVRKaeelRKAEDARKAEAARKAEEERKAEEAR 1218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  532 EQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA 611
Cdd:PTZ00121  1219 KAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  612 EQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDAL-LKEKESLFQAHIQDMNEKTLEKLDKKQMELES 690
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAeAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  691 VSSEL---SEALRARDQLAEELSVLRGDADKMKQALEA---------ELEEQRRHHQ-REVGSISEQQELTVRRAEKALK 757
Cdd:PTZ00121  1379 KADAAkkkAEEKKKADEAKKKAEEDKKKADELKKAAAAkkkadeakkKAEEKKKADEaKKKAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  758 DELSRLGALLDERDEHLRERQARVQDLEaHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEK 837
Cdd:PTZ00121  1459 AEEAKKKAEEAKKADEAKKKAEEAKKAD-EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKAD 1537

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  838 SLLTKQVVEMETHKKHVCEELDAQraQVQQLERQRSELEEKVRSLAQLQDSQlknstvEKEQAR-QSLMEKENIILQMRE 916
Cdd:PTZ00121  1538 EAKKAEEKKKADELKKAEELKKAE--EKKKAEEAKKAEEDKNMALRKAEEAK------KAEEARiEEVMKLYEEEKKMKA 1609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  917 EQAK--EIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEK 994
Cdd:PTZ00121  1610 EEAKkaEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK 1689

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  995 QFNAQILEMAQANSAgisDTVSRLEENQRQQIESLTGAHQRKLDDVIEAwekklsQQAAELRDKHAEQMEEKEqglgELR 1074
Cdd:PTZ00121  1690 AAEALKKEAEEAKKA---EELKKKEAEEKKKAEELKKAEEENKIKAEEA------KKEAEEDKKKAEEAKKDE----EEK 1756

                          730       740
                   ....*....|....*....|....*....
gi 1907199001 1075 QKVRIVQSEKEELTKEVARLKEAVSGQDV 1103
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEIRKEKEAVIEEEL 1785
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 494-1326 3.22e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 3.22e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  494 KEQELSRRLEARERElqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiLTESENKLQELGQEAEAYRTRILE 573
Cdd:TIGR02169  172 KEKALEELEEVEENI--ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  574 LETSLEKS---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREK 650
Cdd:TIGR02169  249 LEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  651 YQQEKDALLKEKESL---------FQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ 721
Cdd:TIGR02169  327 LEAEIDKLLAEIEELereieeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  722 ALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSRLGALlderdehlrerQARVQDLEAHLQKSAGELQQALAK 801
Cdd:TIGR02169  407 ELDRLQEELQRLSEE------------LADLNAAIAGIEAKINEL-----------EEEKEDKALEIKKQEWKLEQLAAD 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  802 LDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEK-VR 880
Cdd:TIGR02169  464 LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyAT 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  881 SLAQLQDSQLKNSTVEKEQARQSLMEkenIILQMREEQAKEIEILKqtLSSKEESISILHEE----YETKFKNQEKRMEK 956
Cdd:TIGR02169  540 AIEVAAGNRLNNVVVEDDAVAKEAIE---LLKRRKAGRATFLPLNK--MRDERRDLSILSEDgvigFAVDLVEFDPKYEP 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  957 IKQKA------KEMQETKKKLLDQEAKLKKELEntvlelsqkekqfnaqILEMAQANSAGiSDTVSRLEENQRQQIESLt 1030
Cdd:TIGR02169  615 AFKYVfgdtlvVEDIEAARRLMGKYRMVTLEGE----------------LFEKSGAMTGG-SRAPRGGILFSRSEPAEL- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1031 gahqRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1110
Cdd:TIGR02169  677 ----QRLRERLEGLKRELSSLQSELRRIENR-LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1111 QLEQKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSlQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslHE 1190
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALN-DLEARLS-HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR----LT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1191 LSKKSLEDKSLNLKSLLEELASQLDSRCERTKALleaktnelvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSE 1270
Cdd:TIGR02169  826 LEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------------NGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1271 LEAQLTQLTEEQRTLKSsfqqvtnQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQ 1326
Cdd:TIGR02169  894 LEAQLRELERKIEELEA-------QIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1832-2136 2.89e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 2.89e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1832 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1911
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1912 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 1991
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1992 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 2071
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001 2072 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2136
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1512-2079 3.01e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 3.01e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1512 DLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1591
Cdd:COG1196    250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1592 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQryAKDTENRLS 1671
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA--AAELAAQLE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1672 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1751
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELL 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1752 LEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETGNNtgvkqnwasVVD 1829
Cdd:COG1196    484 EELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQNI---------VVE 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1830 SVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQS 1909
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1910 NVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 1989
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1990 LMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK-------EDDLRRTA 2049
Cdd:COG1196    715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALgpvnllaIEEYEELE 794

                          570       580       590
                   ....*....|....*....|....*....|
gi 1907199001 2050 RRYeeildareEEMTGKVTDLQTQLEELQK 2079
Cdd:COG1196    795 ERY--------DFLSEQREDLEEARETLEE 816
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 512-1198 7.08e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 64.86  E-value: 7.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  512 QMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 591
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  592 LAVHLEAEKNKHNKELTALAEQHR------TEVEGLQQQQDSLWTERLQSLSQQHqAAVEELREKYQQEKDALLKEKESL 665
Cdd:pfam12128  309 ELSAADAAVAKDRSELEALEDQHGafldadIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTAKYNRRRSKIKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  666 FQAHIQDMNEKTLEKLDKKQMELESVSSELsEALRA--RDQLAEELSVLRGDADKMKQAL------------EAELEEQR 731
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDL-QALESelREQLEAGKLEFNEEEYRLKSRLgelklrlnqataTPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  732 RHHQREVGSISEQQElTVRRAEKALKDELSRLGALLDERDEHLRERQARVQdleahlqksagELQQALAKLDLLHSEQSA 811
Cdd:pfam12128  467 ENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLE-----------ERQSALDELELQLFPQAG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  812 A-----REQAGAYEEQLAQMQQKVLDLETEkslLTKQVVEMETHKKHVCE--ELDAQRAQV-------QQLERQRSELEE 877
Cdd:pfam12128  535 TllhflRKEAPDWEQSIGKVISPELLHRTD---LDPEVWDGSVGGELNLYgvKLDLKRIDVpewaaseEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  878 KV---RSLAQLQDSQLKnstvekeQARQSLmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYET-KFKNQEKR 953
Cdd:pfam12128  612 ALqsaREKQAAAEEQLV-------QANGEL-----------EKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKAL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  954 MEKIKQKAKEMQ--ETKKKLLDQEAKL-KKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLT 1030
Cdd:pfam12128  674 AERKDSANERLNslEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1031 GAHQRKLD--DVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRivqsekEELTKEVARLKEAVSGQDVALAGL 1108
Cdd:pfam12128  754 TWYKRDLAslGVDPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQ------ETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1109 QGQLEQKSA-VIVSLSERESQLQSQvEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSeLTGQVQAAEKELQSCKS 1187
Cdd:pfam12128  827 QQQLARLIAdTKLRRAKLEMERKAS-EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDY 904

                          730
                   ....*....|.
gi 1907199001 1188 LHELSKKSLED 1198
Cdd:pfam12128  905 LSESVKKYVEH 915
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1443-2134 7.41e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 7.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1443 KKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKM---EKKECDLETALKT 1519
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1520 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELG 1599
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1600 TVKKELEHVNSSVKSRDGELKALEDKLEL----ESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKdTENRLSELSA 1675
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1676 QLKEREKQVHSLEDKLKNLE-------------SSPHPEVPAVSR------------------SMQSVAASPEQEAPDSQ 1724
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSElisvdegyeaaieaalggRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1725 DCTHKACKERLCMLQRRLSEKEKL----LRRLEQGEGEARP-----SQPEAQHRALSGKLDCTR-----------ARQLE 1784
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIqgndREILKNIEGFLGVakdlvKFDPKLRKALSYLLGGVLvvddldnalelAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1785 DHVLIGCLPEEL---------EEKMKCSLIVSQpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESD 1855
Cdd:TIGR02168  643 PGYRIVTLDGDLvrpggvitgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1856 LVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLED-RPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1934
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1935 LSKEVARLQKELRALRREHQQeldilkreceqeAEEKLKQEQEDLELKhtstlKQLMREFNTQLAQKEQELERTVQEtID 2014
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAAN------------LRERLESLERRIAAT-----ERRLEDLEEQIEELSEDIESLAAE-IE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2015 KAQEVEAELLESHQEETQQLhrkiaEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKds 2094
Cdd:TIGR02168  863 ELEELIEELESELEALLNER-----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE-- 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199001 2095 VTILELQTQLAQK--------TTLISDSKLKEQELREQVHNLEDRLKR 2134
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 436-1241 7.46e-10

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 64.61  E-value: 7.46e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  436 KMEMDEQMKAVERASEEERLRLQHELSrvRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRI 515
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKE--QAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  516 ALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVH 595
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  596 LEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWT---ERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQD 672
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQleeELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  673 MNEKTLEKLDKKQMELESVSSELSEALRAR---------DQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISE 743
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKlteekeeleKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  744 QQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 823
Cdd:pfam02463  496 EERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  824 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 903
Cdd:pfam02463  576 GARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLE 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  904 LMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELE 983
Cdd:pfam02463  656 EGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQ-LEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  984 NTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQM 1063
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1064 EEKEQGLGELRQKVRIVQSEKEELTKE-VARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGC 1142
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALElKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1143 SLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTK 1222
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810
                   ....*....|....*....
gi 1907199001 1223 ALLEAKTNELVCTSRDKAD 1241
Cdd:pfam02463  975 VNLMAIEEFEEKEERYNKD 993
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 130-725 3.19e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 3.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  130 LSREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREKKKLQGilsqsqdkslrRISELREELQMDQQAKKHLQDEFDAC 209
Cdd:COG1196    225 LEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA-----------ELEELRLELEELELELEEAQAEEYEL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  210 LEEKDQyisvLQTQVSLLKQRLQNgpmnvdapkplppgelqaevhgdtEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENL 289
Cdd:COG1196    294 LAELAR----LEQDIARLEERRRE------------------------LEERLEELEEELAELEEELEELEEELEELEEE 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  290 LQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQML 369
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  370 ETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERA 449
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  450 SEEERLRLQHE--LSRVRQEAASMAKKNSEEQVAAlqklhAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKL 527
Cdd:COG1196    506 FLEGVKAALLLagLRGLAGAVAVLIGVEAAYEAAL-----EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  528 TQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRT--RILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNK 605
Cdd:COG1196    581 KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLlgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  606 ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESlfQAHIQDMNEKTLEKLDKKQ 685
Cdd:COG1196    661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEE--ELEEEALEEQLEAEREELL 738

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1907199001  686 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEA 725
Cdd:COG1196    739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 815-1697 3.89e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 62.37  E-value: 3.89e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  815 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRseleeKVRSLAQLQDSQLKNST 894
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR-----EIVKSYENELDPLKNRL 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  895 VEKEQARQSLMEKENII-------LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 967
Cdd:TIGR00606  255 KEIEHNLSKIMKLDNEIkalksrkKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  968 KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKK 1047
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEA-----KT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1048 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSEres 1127
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1128 qlQSQVEKlEADLGCSLSEKLSLQEELAELklladksqlrvseltgqvqaaekELQSCKSLHELSKKSLEDKSLNLKSLL 1207
Cdd:TIGR00606  487 --LSKAEK-NSLTETLKKEVKSLQNEKADL-----------------------DRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1208 EELASQLDSRCERTKAlleaktnelvctsrdKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKS 1287
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKS---------------RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1288 SFQQVTNQLEEKEKQIKTMKADI------EGLLTEKEALQQE---GGQQRQAASEKESCITQLKKELAENINAVTLLREE 1358
Cdd:TIGR00606  606 NKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1359 LSEKKSEIASLSKQLSDLgaqlesSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNK 1438
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSK------LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1439 FSEWKKKAQSRLAQHQSTIKDLQAQLDVKA--TDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLEta 1516
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE-- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1517 LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRlQHLEELGEEKDNKVREAEETVLRLREHVSSLEA 1596
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSLIREIKDAKEQDSPLET 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1597 elgTVKKELEHVNSSVKSRDGELKALEDKLElesaakvELKRKAEQKIAAiRKQLLSQMEEKTQRYAKDTENRLSELSAQ 1676
Cdd:TIGR00606  917 ---FLEKDQQEKEELISSKETSNKKAQDKVN-------DIKEKVKNIHGY-MKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900
                   ....*....|....*....|.
gi 1907199001 1677 LKEREKQVHSLEDKLKNLESS 1697
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQD 1006
PTZ00121 PTZ00121
MAEBL; Provisional
 1422-2138 4.86e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.86e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1422 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1500
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1501 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1579
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1580 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1655
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1656 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1735
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1736 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1815
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1816 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1895
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1896 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1974
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1975 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 2049
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2050 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 2122
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907199001 2123 EQVHNLEDRLKRYEKN 2138
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
316-917 5.69e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 5.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  316 EQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEdEIAQLRSHIKQMTTQGEE 395
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELRE-ELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  396 L---------REQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASE--EERLRLQHELSRV 464
Cdd:PRK03918   240 IeelekelesLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEylDELREIEKRLSRL 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  465 RQEAASMAKKNSEeqvAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELEL 544
Cdd:PRK03918   320 EEEINGIEERIKE---LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  545 QKKAilTESENKLQELGQEAEAYRTRILELETSLEKsLQESKT------------QSEHLAVHLEAEKNKHNKELTALAE 612
Cdd:PRK03918   397 EKAK--EEIEEEISKITARIGELKKEIKELKKAIEE-LKKAKGkcpvcgrelteeHRKELLEEYTAELKRIEKELKEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  613 QHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFqahiqdmnEKTLEKLDKKQMELESVS 692
Cdd:PRK03918   474 KERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY--------EKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  693 SELSEalrardqlAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSrlgaLLDERDE 772
Cdd:PRK03918   546 KELEK--------LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE----LKDAEKE 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  773 hLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGayEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKK 852
Cdd:PRK03918   614 -LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001  853 HVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREE 917
Cdd:PRK03918   691 EIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEE 755
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 519-985 5.91e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 5.91e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  519 KSRSEYLKLTQEKEQQESLALEELE--LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAVH 595
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTeiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  596 LE----AEKNKHNKELTA----LAEQHRTEVEGLQQQQDSL---------WTERLQSLSQQHQAAVEELREKYQQ--EKD 656
Cdd:TIGR04523  201 LLlsnlKKKIQKNKSLESqiseLKKQNNQLKDNIEKKQQEInektteisnTQTQLNQLKDEQNKIKKQLSEKQKEleQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  657 ALLKEKESLFQA-----------HIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKmKQALEA 725
Cdd:TIGR04523  281 KKIKELEKQLNQlkseisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-SESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  726 ELEEQRRHHQREVGSISEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLL 805
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  806 HSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQL 885
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  886 QDSQLKNS---TVEKEQARQSLMEKENIILQMREEQAKEIeiLKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAK 962
Cdd:TIGR04523  519 ISSLKEKIeklESEKKEKESKISDLEDELNKDDFELKKEN--LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500
                   ....*....|....*....|....*.
gi 1907199001  963 EMQETKKKLLDQEAK---LKKELENT 985
Cdd:TIGR04523  597 EKKDLIKEIEEKEKKissLEKELEKA 622
PTZ00121 PTZ00121
MAEBL; Provisional
 1436-2096 6.41e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 6.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1436 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKME----KKE 1510
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDArKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEakkaEEE 1248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1511 CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGE--EKDNKVREAEETVLRLR 1588
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAK 1328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1589 EHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEqkiAAIRKQLLSQMEEKTQRYAKDTEN 1668
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKK 1405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1669 RLSELSAQlKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKL 1748
Cdd:PTZ00121  1406 KADELKKA-AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1749 LRRLEQGEGEARPSQPEAQHRAlSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVV 1828
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1829 DSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQ 1908
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1909 SNVGTVDGLRSDLESKLTGAERDKQKlSKEVARLQKELRALRREHQQELDILKRECEQ--EAEEKLKQEQEDLELKHTST 1986
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK 1722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1987 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGK 2066
Cdd:PTZ00121  1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802

                          650       660       670
                   ....*....|....*....|....*....|
gi 1907199001 2067 VTDLQTQLEELQKKYQQRLEQEESTKDSVT 2096
Cdd:PTZ00121  1803 IFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1270-2085 6.64e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 6.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1270 ELEAQLTQLteEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENI 1349
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1350 NAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSAL 1429
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1430 EQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK 1508
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLeRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1509 KECDLETALKTQTARVVELEDCVTQRKKEVESLN---ETLKNYNQQRDTEHSGLVQRLQHLEELGE---------EKDNK 1576
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlseliSVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1577 VREAEETVlrLREHVSSLEAElgTVKKELEHVNSSVKSRDGELKALEdkLELESAAKVELKRKAEQKIAAIRKQLLSQME 1656
Cdd:TIGR02168  535 YEAAIEAA--LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1657 EKTQRYAKDTENRLS------------ELSAQLKEREKQVhSLEDKLknleSSPHPEVPAVSRSMQSVAASPEQEAPDSQ 1724
Cdd:TIGR02168  609 KFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIV-TLDGDL----VRPGGVITGGSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1725 DCThKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--LIGCLPEELEEKMKC 1802
Cdd:TIGR02168  684 EKI-EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLeeRIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1803 SLIVSQPMGEETGNNTGVKQNWASVVDSVQKtlqekeltcqaLEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQ 1882
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQIEQ-----------LKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1883 EMDGENKCVEVLEDRPEENSQSHE-IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALR---REHQQELD 1958
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1959 ILKRECE--QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLaqkeQELERTVQETIDKAQEVEAElLESHQEETQQLHR 2036
Cdd:TIGR02168  912 ELRRELEelREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRR-LKRLENKIKELGP 986

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199001 2037 KIAEKEDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRL 2085
Cdd:TIGR02168  987 VNLAAIEEYEELKERYDF-LTAQKEDLTEAKETLEEAIEEIDREARERF 1034
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 944-1547 8.17e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.80  E-value: 8.17e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  944 ETKFKNQEKRMEKI----KQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANSAGISD-TVSRL 1018
Cdd:TIGR04523   32 DTEEKQLEKKLKTIknelKNKEKELKNLDKNLNKDEEK-INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1019 EENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAV 1098
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1099 SGQDVALAglqgQLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklslqEELAELKLLADKSQLRVSELTGQVQAA 1178
Cdd:TIGR04523  190 DKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELK--------------KQNNQLKDNIEKKQQEINEKTTEISNT 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1179 EKELQSCKSLHELSKKSLEDKSLNL---KSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTA 1255
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1256 TVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKE 1335
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1336 SCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES-SISPSDKAEAISALSKQHEEQELQLQAQLQEL 1414
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1415 SLKV---DALSKEKMSALEQVDHWSNKFSEWKKKAQ---SRLAQHQSTIKDLQAQLDVKATDAREKeeqicLLKEDLDRQ 1488
Cdd:TIGR04523  492 KSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKE-----NLEKEIDEK 566

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 1489 NKKFECLKGEMEVRKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1547
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKQelidqkekekKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1531-2136 1.17e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.84  E-value: 1.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1531 VTQRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNS 1610
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEE----LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1611 SVKSRDGELKALEDKLELESAAKVELKRKAEQ--------------------KIAAIRKQLLSQMEEKTQRY------AK 1664
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAEleekleelkeelesleaeleELEAELEELESRLEELEEQLetlrskVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1665 DTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSE 1744
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1745 KEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV------------LIGCLPEELE--------------- 1797
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkallknqsglsgILGVLSELISvdegyeaaieaalgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1798 -----------------------EKMKCSLIV--------SQPMGEETGNNTGVKQNWASVVDSVQKTLQE--------- 1837
Cdd:TIGR02168  546 rlqavvvenlnaakkaiaflkqnELGRVTFLPldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggv 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1838 ---KELTcQALEQRVKE--------LESDLVRERGAHRLEVEKLTLkyeKSQSSQQEMDGENKCVEVLEdrpeenSQSHE 1906
Cdd:TIGR02168  626 lvvDDLD-NALELAKKLrpgyrivtLDGDLVRPGGVITGGSAKTNS---SILERRREIEELEEKIEELE------EKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1907 IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTST 1986
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1987 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL------LESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDARE 2060
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtllneeAANLRERLESLERRIAATERRLEDLEEQIEE-LSEDI 854

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 2061 EEMTGKVTDLQTQLEELQKKYQQRLEQEESTKdsVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 2136
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLE--EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1267-1697 1.22e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.42  E-value: 1.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1267 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELA 1346
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1347 ENINAVTllREELSEKKSEIASLSKQLSDLGAQLESSISP-SDKAEAISALSKQHEEQELQLQAQLQELSLKVDA---LS 1422
Cdd:TIGR04523  299 DLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEiekLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1423 KEKMSALEQVDHWSNKFSEWKKKAQsrlaQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVR 1502
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1503 K---SKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVRE 1579
Cdd:TIGR04523  453 EliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1580 AEETVLRLREHVSSLEAELGTVKKEL--EHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKiAAIRKQLLSQMEE 1657
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEE 607

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1907199001 1658 KTQryakdtenRLSELSAQLKEREKQVHSLEDKLKNLESS 1697
Cdd:TIGR04523  608 KEK--------KISSLEKELEKAKKENEKLSSIIKNIKSK 639
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1267-1695 1.36e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.36e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1267 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1336
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1337 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1412
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1413 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1488
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1489 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1557
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1558 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1627
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1628 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
975-1379 1.52e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.05  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  975 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTgahqrKLDDVIEAWEKKLsqqaae 1054
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRD-----EADEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1055 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1134
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1135 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 1201
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1202 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1247
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1248 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1327
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1328 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1379
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
460-985 1.80e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.93  E-value: 1.80e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  460 ELSRVRQEAASMakknsEEQVAALQKLhaEELASKEQELSRRLEARERELQeqmrialeksrseylKLTQEKEQQESLAL 539
Cdd:COG4913    236 DLERAHEALEDA-----REQIELLEPI--RELAERYAAARERLAELEYLRA---------------ALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  540 EELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVE 619
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  620 GLQQQQDSLWteRLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmnektlEKLDKKQMELESVSSEL-SEA 698
Cdd:COG4913    374 PLPASAEEFA--ALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL---------RELEAEIASLERRKSNIpARL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  699 LRARDQLAEELSV-------------LRGDADKMKQALEAELEEQRR------HHQREVGSISEQQELTVR-RAEKALKD 758
Cdd:COG4913    443 LALRDALAEALGLdeaelpfvgelieVRPEEERWRGAIERVLGGFALtllvppEHYAAALRWVNRLHLRGRlVYERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  759 ELSRLGALLDER-----------------DEHLRERQARV-----QDLEAH--------LQKSAGEL------------- 795
Cdd:COG4913    523 LPDPERPRLDPDslagkldfkphpfrawlEAELGRRFDYVcvdspEELRRHpraitragQVKGNGTRhekddrrrirsry 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  796 ---QQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvemETHKKHVCEELDAQ--RAQVQQLER 870
Cdd:COG4913    603 vlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-------QRLAEYSWDEIDVAsaEREIAELEA 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  871 QRSELEEKVRSLAQLQD--SQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISI-LHEEYETKF 947
Cdd:COG4913    676 ELERLDASSDDLAALEEqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1907199001  948 KNQEKRmEKIKQKAKEMQETKKKLLDQEAKLKKELENT 985
Cdd:COG4913    756 AAALGD-AVERELRENLEERIDALRARLNRAEEELERA 792
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 273-988 2.10e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 2.10e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  273 AKTLEMLQQRVKRQ-ENLLQRCKETIGSHK---EQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDakn 348
Cdd:TIGR02169  271 EQLLEELNKKIKDLgEEEQLRVKEKIGELEaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE--- 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  349 liEQLEQDKGMVITETKRQMLETL----ELKEDEIAQLRSHIKQMTTQGEELREQKEKSERaalyeqdwafeELEKALST 424
Cdd:TIGR02169  348 --ERKRRDKLTEEYAELKEELEDLraelEEVDKEFAETRDELKDYREKLEKLKREINELKR-----------ELDRLQEE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  425 AQKTEDAQRRMKMEMdEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQvaalQKLHAeeLASKEQELSRRLEA 504
Cdd:TIGR02169  415 LQRLSEELADLNAAI-AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE----QELYD--LKEEYDRVEKELSK 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  505 RERELQ--EQMRIALEKSRSEYLKLTQEKEQ-------QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELE 575
Cdd:TIGR02169  488 LQRELAeaEAQARASEERVRGGRAVEEVLKAsiqgvhgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELL 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  576 TSLEKS----LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTE------------VEGLQQQQDSLWTERLQSL--- 636
Cdd:TIGR02169  568 KRRKAGratfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpafkyvfgdtlvVEDIEAARRLMGKYRMVTLege 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  637 -----------------SQQHQAAVEELREKYQQEKDALLKEKESLFQ--AHIQDMNEKTLEKLDKKQMELESVSSELSE 697
Cdd:TIGR02169  648 lfeksgamtggsraprgGILFSRSEPAELQRLRERLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEIEQ 727

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  698 ALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsISEQQEL--TVRRAEKALKDELSR-----LGALLDER 770
Cdd:TIGR02169  728 LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDlhKLEEALNDLEARLSHsripeIQAELSKL 803

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  771 DEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETH 850
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR 883

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  851 KKHVCEELDAQRAQVQQLERQRSELEEKVrslaQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKE--IEILKQT 928
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQI----EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAE 959

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907199001  929 LSSKEESISILHE---EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 988
Cdd:TIGR02169  960 LQRVEEEIRALEPvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1532-2087 2.76e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1532 TQRKKEVESLNETLKNYNQQRDTEHsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEA--------ELGTVKK 1603
Cdd:COG4913    268 RERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQLER 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1604 ELEHVNSSVKSRDGELKALEDKLelesaAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQ 1683
Cdd:COG4913    346 EIERLERELEERERRRARLEALL-----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1684 VHSLEDKLKNLESSP---HPEVPAVSRSMQSVAASPEQEAP--------DSQDCTHKACKER------LCML--QRRLS- 1743
Cdd:COG4913    421 LRELEAEIASLERRKsniPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAIERvlggfaLTLLvpPEHYAa 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1744 -----EKEKLLRRL---EQGEGEARPSQPEAQHRALSGKLD----------------------CTRARQLEDH---VLIG 1790
Cdd:COG4913    501 alrwvNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvcVDSPEELRRHpraITRA 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1791 CL---PEELEEKmkcslivsqpmgeetGNNTGVKQNWASVVDSVQKtLQEKELTCQALEQRVKELESDLVRERGAHRLEV 1867
Cdd:COG4913    581 GQvkgNGTRHEK---------------DDRRRIRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1868 EKLTL--KYEKSQSSQQEMDGENKCVEVLEDRPEE----NSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVAR 1941
Cdd:COG4913    645 ERREAlqRLAEYSWDEIDVASAEREIAELEAELERldasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1942 LQKELRALRREHQQELDILKRECEQEAEEKLKQE-QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE 2020
Cdd:COG4913    725 AEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 2021 AELLES--HQEETQQLHRKIaeKEDDLrrtARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQ 2087
Cdd:COG4913    805 ADLDADleSLPEYLALLDRL--EEDGL---PEYEERFKELLNENSIEFVADLLSKLRRAIREIKERIDP 868
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2164-2207 3.59e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 51.45  E-value: 3.59e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199001  2164 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 2207
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
PTZ00121 PTZ00121
MAEBL; Provisional
 977-1695 6.00e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 6.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  977 KLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 1056
Cdd:PTZ00121  1028 KIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTE 1107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1057 DKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSlseRESQLQSQVEKL 1136
Cdd:PTZ00121  1108 TGKAEEARKAEEAKKKAEDARKAEEARKAE---DARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEAA 1181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1137 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAE-----KELQSCKSLHELSKKSLEDKSLNLKSLLEELA 1211
Cdd:PTZ00121  1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1212 SQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTatvgeallRRMGQVSELEAQLTQLTEEQRTLKSSFQQ 1291
Cdd:PTZ00121  1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--------DEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1292 VTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAvtllrEELSEKKSEIASLSK 1371
Cdd:PTZ00121  1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKAD 1408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1372 QLSDLGAQLESSISPSDKAEAIsalsKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSrlA 1451
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEK----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--A 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1452 QHQSTIKDLQAQLDVKATDAREKEEQicllKEDLDRQNKKFECLKGEmEVRKSKMEKKECDLETA---------LKTQTA 1522
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKAeekkkadelKKAEEL 1557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1523 RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEaelgtVK 1602
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-----EK 1632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1603 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREK 1682
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                          730
                   ....*....|...
gi 1907199001 1683 QVHSLEDKLKNLE 1695
Cdd:PTZ00121  1713 EEKKKAEELKKAE 1725
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 394-1204 7.04e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 7.04e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  394 EELREQKEKSERAALyEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV------ERASEEERLRLQHELSRVRQE 467
Cdd:pfam02463  173 EALKKLIEETENLAE-LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyllyldYLKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  468 AASMAKK---NSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELEL 544
Cdd:pfam02463  252 EIESSKQeieKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  545 QKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQEsktQSEHLAVHLEAEknKHNKELTALAEQHRTEVEGLQQQ 624
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQL---EEELLAKKKLES--ERLSSAAKLKEEELELKSEEEKE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  625 QDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQ 704
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  705 LAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDL 784
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  785 EAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKS--LLTKQVVEMETHKKHVCEELDAQR 862
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKraKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  863 AQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEE 942
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  943 YETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQ--------ANSAGISDT 1014
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEeekeeklkAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1015 VSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARL 1094
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1095 KEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQ 1174
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|
gi 1907199001 1175 VQAAEKELQSCKSLHELSKKSLEDKSLNLK 1204
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELE 996
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
365-949 1.43e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  365 KRQMLETLELKEDeIAQLRSHIKQ---MTTQGEELREQKEKSERAALyeqdwAFEELEKALSTAQKTEDAQRRMKMEMDE 441
Cdd:COG4913    214 REYMLEEPDTFEA-ADALVEHFDDlerAHEALEDAREQIELLEPIRE-----LAERYAAARERLAELEYLRAALRLWFAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  442 QMKAVERAsEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmrialEKSR 521
Cdd:COG4913    288 RRLELLEA-ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEER-----ERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  522 SEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQEsktqsehlavhLEAEKN 601
Cdd:COG4913    362 ARLEALLAALGLP---------------LPASAEEFAALRAEAAALLEALEEELEALEEALAE-----------AEAALR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  602 KHNKELTALaeqhRTEVEGLQQQQDslwterlqSLSQQHQAAVEELREKYQQEKDAL--------LKEKESLFQ------ 667
Cdd:COG4913    416 DLRRELREL----EAEIASLERRKS--------NIPARLLALRDALAEALGLDEAELpfvgelieVRPEEERWRgaierv 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  668 ------------AHIQDMNEKTLEKLDKKQMELESVSSELSEALRAR---DQLAEELSVLRGDAdkmKQALEAEL----- 727
Cdd:COG4913    484 lggfaltllvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRldpDSLAGKLDFKPHPF---RAWLEAELgrrfd 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  728 ------EEQRRHHQREV---GSISEQQeltvRRAEKALKDELSR---LG----ALLDERDEHLRERQARVQDLEAHLQKS 791
Cdd:COG4913    561 yvcvdsPEELRRHPRAItraGQVKGNG----TRHEKDDRRRIRSryvLGfdnrAKLAALEAELAELEEELAEAEERLEAL 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  792 AGELQQALAKLDLLH--SEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLE 869
Cdd:COG4913    637 EAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELE----AELEELEEELDELK 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  870 RQRSELEEKVRSLAQLQDS---QLKNSTVEKEQARQSLMEK-------ENIILQMREEQAKEIEILKQTLSSKEESISIL 939
Cdd:COG4913    713 GEIGRLEKELEQAEEELDElqdRLEAAEDLARLELRALLEErfaaalgDAVERELRENLEERIDALRARLNRAEEELERA 792

                          650
                   ....*....|
gi 1907199001  940 HEEYETKFKN 949
Cdd:COG4913    793 MRAFNREWPA 802
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 391-980 1.67e-07

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 56.67  E-value: 1.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  391 TQGEELREQKEKSERaalyEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAAS 470
Cdd:pfam05557    9 ARLSQLQNEKKQMEL----EHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKY 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  471 MAKKNSEEQVAALQKLHAEELAS-KEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAI 549
Cdd:pfam05557   85 LEALNKKLNEKESQLADAREVIScLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSS 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  550 LTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHleaEKNKHNKELTALAEQHRTEVEGLQQQQDSlw 629
Cdd:pfam05557  165 LAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR---EHNKHLNENIENKLLLKEEVEDLKRKLER-- 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  630 terlQSLSQQHQAAVEELREKYQQEkdalLKEKESLFQAHIQDMNE--------KTLEKLDKKQME-LESVSSELSEALR 700
Cdd:pfam05557  240 ----EEKYREEAATLELEKEKLEQE----LQSWVKLAQDTGLNLRSpedlsrriEQLQQREIVLKEeNSSLTSSARQLEK 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  701 ARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELtVRRAEKALKDELSRlgallderDEHLRERQAR 780
Cdd:pfam05557  312 ARRELEQELAQYLKKIEDLNKKLK-RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELTM--------SNYSPQLLER 381

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  781 VQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVldlETEKSLLTKQVVEmethkkHVCEELDA 860
Cdd:pfam05557  382 IEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE---SLADPSYSKEEVD------SLRRKLET 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  861 QRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVekeqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH 940
Cdd:pfam05557  453 LELERQRLREQKNELEMELERRCLQGDYDPKKTKV--------LHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLE 524

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1907199001  941 EEYETKfknQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 980
Cdd:pfam05557  525 DDLEQV---LRLPETTSTMNFKEVLDLRKELESAELKNQR 561
mukB PRK04863
chromosome partition protein MukB;
513-884 1.78e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 56.89  E-value: 1.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  513 MRIALEKSRSEYLKLTQEKEQQeslaleelelQKKAILTESENKLQELGQEAEAyrtrILELETSLEkslQESKTQSEHL 592
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELY----------TSRRQLAAEQYRLVEMARELAE----LNEAESDLE---QDYQAASDHL 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  593 AVHLEAEK--NKHNK------ELTALAEQHRTEVEGLQQQQDSLWTE---------RLQSLSQQHQAAVEELREK---YQ 652
Cdd:PRK04863   338 NLVQTALRqqEKIERyqadleELEERLEEQNEVVEEADEQQEENEARaeaaeeevdELKSQLADYQQALDVQQTRaiqYQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  653 QEKDALLKEKE-----SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVL--------RGDADKM 719
Cdd:PRK04863   418 QAVQALERAKQlcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsRSEAWDV 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  720 KQALEAELEEQRRHHQREVGSISEQQELTVR-----RAEKALKDELSRLGALLDERDE---HLRERQARVQDLE---AHL 788
Cdd:PRK04863   498 ARELLRRLREQRHLAEQLQQLRMRLSELEQRlrqqqRAERLLAEFCKRLGKNLDDEDEleqLQEELEARLESLSesvSEA 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  789 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDletekSLLTKQvvEMETHKKHVCEELDAQRAQVQQL 868
Cdd:PRK04863   578 RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGE-----EFEDSQ--DVTEYMQQLLERERELTVERDEL 650

                          410
                   ....*....|....*.
gi 1907199001  869 ERQRSELEEKVRSLAQ 884
Cdd:PRK04863   651 AARKQALDEEIERLSQ 666
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1550-2134 2.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 2.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1550 QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLE-L 1628
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELArL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1629 ESAAKVELKRKAEqkIAAIRKQLLSQMEEKTQRYAKDTEnRLSELSAQLKEREKQVHSLEDKLKNLESSphpevpavsRS 1708
Cdd:COG1196    301 EQDIARLEERRRE--LEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELEEAEAELAEAEEA---------LL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1709 MQSVAASPEQEApdsqdctHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDCTRARQLEDHVL 1788
Cdd:COG1196    369 EAEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1789 IGCLPEELEEKmkcslivsqpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVE 1868
Cdd:COG1196    438 EEEEEALEEAA-----------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1869 KLTLKYEKSQSSQQEMDGEnkcVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK-------LSKEVAR 1941
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGA---VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIR 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1942 LQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEA 2021
Cdd:COG1196    584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2022 ELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTILELQ 2101
Cdd:COG1196    664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199001 2102 TQLAQKTTLISD--SKLKEQELREQVHNLEDRLKR 2134
Cdd:COG1196    744 EEELLEEEALEElpEPPDLEELERELERLEREIEA 778
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 294-594 2.62e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 55.90  E-value: 2.62e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  294 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVITETKRQML 369
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  370 ETLELKEDEIAQLRSHIKQM-------TTQGEELREQKEKSERAALYEQD----WAFEELEKALSTAQKTEDAQRRMKME 438
Cdd:pfam17380  361 ELERIRQEEIAMEISRMRELerlqmerQQKNERVRQELEAARKVKILEEErqrkIQQQKVEMEQIRAEQEEARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  439 MDEQMKAVERASEEERLRlQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASK--EQELSRRLEARERElqEQMRIA 516
Cdd:pfam17380  441 EEERAREMERVRLEEQER-QQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKilEKELEERKQAMIEE--ERKRKL 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  517 LEKSRSEYLKLTQEKEQQeslaLEELELQKKAILTESENKLQELGQEAEAYRTRI--LELETSLEKSLQESKTQSEHLAV 594
Cdd:pfam17380  518 LEKEMEERQKAIYEEERR----REAEEERRKQQEMEERRRIQEQMRKATEERSRLeaMEREREMMRQIVESEKARAEYEA 593
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 465-1076 2.76e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.39  E-value: 2.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  465 RQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEA-----RERELQEQMRIALEKSRSEYLKLTQEKEQQESLAL 539
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvakdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  540 EELELQKKAiLTESENKLQElgqeaeAYRTRILELetslekslqesktqSEHLAVHLEAEKNKHNKELTALAEQHrTEVE 619
Cdd:pfam12128  357 ENLEERLKA-LTGKHQDVTA------KYNRRRSKI--------------KEQNNRDIAGIKDKLAKIREARDRQL-AVAE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  620 GLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEK----DALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL 695
Cdd:pfam12128  415 DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATATPELLLQLENFDERIERAREEQEAANAEVERLQSEL 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  696 SEALRARDQLAEELSVLRGDADKMKQALEaELEEQ------RRHH--QREVGSISEQQELTVRRA------------EKA 755
Cdd:pfam12128  495 RQARKRRDQASEALRQASRRLEERQSALD-ELELQlfpqagTLLHflRKEAPDWEQSIGKVISPEllhrtdldpevwDGS 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  756 LKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAReqaGAYEEQLAQMQQKVLDLET 835
Cdd:pfam12128  574 VGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQAN---GELEKASREETFARTALKN 650

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  836 EKSLLTKQVVEMETHKKHVCEELDAQRA----QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLM-EKENI 910
Cdd:pfam12128  651 ARLDLRRLFDEKQSEKDKKNKALAERKDsaneRLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEgALDAQ 730

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  911 ILQMREEQAKEIEILKQTLSS--------------KEESISILH---EEYETKFKNQEKRMEKIKQKAKEMQETkkkLLD 973
Cdd:pfam12128  731 LALLKAAIAARRSGAKAELKAletwykrdlaslgvDPDVIAKLKreiRTLERKIERIAVRRQEVLRYFDWYQET---WLQ 807

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  974 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEENQRQQIESLTG--AHQRKLDDVIEAWEKKLSQQ 1051
Cdd:pfam12128  808 RRPRLATQLSNIERAISELQQQLARLIADTKLRRAK-LEMERKASEKQQVRLSENLRGlrCEMSKLATLKEDANSEQAQG 886

                          650       660
                   ....*....|....*....|....*
gi 1907199001 1052 AAELRDKHAEQMEEKEQGLGELRQK 1076
Cdd:pfam12128  887 SIGERLAQLEDLKLKRDYLSESVKK 911
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 598-936 2.84e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 2.84e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  598 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQA----HIQDM 673
Cdd:COG3096    278 NERRELSERALELRRELFGARRQLAEEQYRL--VEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekieRYQED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  674 NEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaelEEQRR--HHQREVGSISEQQELTVRR 751
Cdd:COG3096    356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---VQQTRaiQYQQAVQALEKARALCGLP 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  752 --AEKALKDELSRLGALLDERDEHLRERQARVQDLEAH----------LQKSAGE------------------------- 794
Cdd:COG3096    433 dlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayelVCKIAGEversqawqtarellrryrsqqalaq 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  795 ----LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLER 870
Cdd:COG3096    513 rlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001  871 QRSELEEKVRSLAQLQDS--QLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESI 936
Cdd:COG3096    593 RIKELAARAPAWLAAQDAleRLREQSGEALADSQEVTAA----MQQLLEREREATVERDELAARKQAL 656
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 778-999 3.15e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 3.15e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  778 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 857
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  858 LDAQRAQVQQLER--QRSELEEKVRSLAQLQDSQ--LKNSTVEKE--QARQSLMEKENIILQMREEQAKEIEILKQTLSS 931
Cdd:COG4942     99 LEAQKEELAELLRalYRLGRQPPLALLLSPEDFLdaVRRLQYLKYlaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001  932 KEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ 999
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
274-772 3.60e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.82  E-value: 3.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  274 KTLEMLQQRVKRQENLLQRC---KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELHMA---EKTKLITQLRDAK 347
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAEterEREELAEEVRDLR 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  348 NLIEQLEQDKGMVITETKR---------QMLETLELKEDE----IAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWA 414
Cdd:PRK02224   286 ERLEELEEERDDLLAEAGLddadaeaveARREELEDRDEElrdrLEECRVAAQAHNEEAESLREDADDLEERAEELREEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  415 fEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERA----------SEEERLRLQHELSRVRQEAASMAK--KNSEEQVAA 482
Cdd:PRK02224   366 -AELESELEEAREAVEDRREEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  483 LQKLHAeelASKEQELSRRLEARERElqeqmrIALEKSRSEYLKLTQEKEQQESLALEELELQKKAI-LTESENKLQELG 561
Cdd:PRK02224   445 AEALLE---AGKCPECGQPVEGSPHV------ETIEEDRERVEELEAELEDLEEEVEEVEERLERAEdLVEAEDRIERLE 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  562 QEAEAYRTRILELETSLEKSlQESKTQSEHLAVHLEAEKNKHNKELTAL---AEQHRTEVEGLQQQQDSLwTERLQSLSQ 638
Cdd:PRK02224   516 ERREDLEELIAERRETIEEK-RERAEELRERAAELEAEAEEKREAAAEAeeeAEEAREEVAELNSKLAEL-KERIESLER 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  639 qhQAAVEELREKYQQEKDALLKEKEslfqaHIQDMNEKTLEKLDKKQMELESVSSELSEAlrardqlaeELSVLRGDADK 718
Cdd:PRK02224   594 --IRTLLAAIADAEDEIERLREKRE-----ALAELNDERRERLAEKRERKRELEAEFDEA---------RIEEAREDKER 657

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001  719 MKQALE------AELEEQRRHHQREVGSI-SEQQEL-TVRRAEKALKDELSRLGALLDERDE 772
Cdd:PRK02224   658 AEEYLEqveeklDELREERDDLQAEIGAVeNELEELeELRERREALENRVEALEALYDEAEE 719
PTZ00121 PTZ00121
MAEBL; Provisional
 683-1491 3.81e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 3.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  683 KKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSR 762
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAED------------ARKAEEARKAEDAK 1152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  763 LGALLDERDEHLRERQARVQDlEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQlaQMQQKVLDLETEKSLltK 842
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAE-DAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEE--RKAEEARKAEDAKKA--E 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  843 QVVEMETHKKhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEI 922
Cdd:PTZ00121  1228 AVKKAEEAKK---DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA 1304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  923 EILKQTLSSKEESisilhEEYETKFKNQEKRMEKIKQKAKEmqetkKKLLDQEAKLKKELENTVLELSQKEKQfnaqile 1002
Cdd:PTZ00121  1305 DEAKKKAEEAKKA-----DEAKKKAEEAKKKADAAKKKAEE-----AKKAAEAAKAEAEAAADEAEAAEEKAE------- 1367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1003 maqansagiSDTVSRLEENQRQQiesltgAHQRKLDDVIEAWEKKlsqQAAELRDKHAEQMEEKEQGlgelrqkvrivQS 1082
Cdd:PTZ00121  1368 ---------AAEKKKEEAKKKAD------AAKKKAEEKKKADEAK---KKAEEDKKKADELKKAAAA-----------KK 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1083 EKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAvivslsERESQLQSQVEKLEAdlgcslSEKLSLQEELAELKLLAD 1162
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKA------EEAKKAEEAKKKAEE------AKKADEAKKKAEEAKKAD 1486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1163 KSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADA 1242
Cdd:PTZ00121  1487 EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKA 1566

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1243 ILARLSQCQRHTATVGEALLRRMGQVSELEaqLTQLTEEQRTLKSsfQQVTNQLEEKEKQIKTMKAdieglltekEALQQ 1322
Cdd:PTZ00121  1567 EEAKKAEEDKNMALRKAEEAKKAEEARIEE--VMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKA---------EEEKK 1633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1323 EGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQhee 1402
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK--- 1710

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1403 qelqlqaqLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLK 1482
Cdd:PTZ00121  1711 --------EAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782


                   ....*....
gi 1907199001 1483 EDLDRQNKK 1491
Cdd:PTZ00121  1783 EELDEEDEK 1791
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
784-1012 4.47e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 55.41  E-value: 4.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  784 LEAHLQKSAGELQQALAKLDllhSEQSAAREQAGAYEEQLAQMQQK--VLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 861
Cdd:COG3206    162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  862 RAQVQQLERQRSELEEKVRSLAQLQ-----DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESI 936
Cdd:COG3206    239 EARLAALRAQLGSGPDALPELLQSPviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  937 SILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL--LDQEAKLKKELENTVL------ELSQKEKQFNAQILEMAQANS 1008
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELrrLEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVPL 398


                   ....
gi 1907199001 1009 AGIS 1012
Cdd:COG3206    399 KPVS 402
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 743-1307 4.97e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 4.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  743 EQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSeqsaareqagayeeQ 822
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN--------------K 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  823 LAQMQQKVLDLETEKS---LLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTVE 896
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikKQLSEKQKE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  897 KEQARQSLMEKENIILQMReeqaKEIEILKQtlsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA 976
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLK----SEISDLNN------QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  977 KLKKELENTVLELSQKEKQfnaqilemaqansagisdtvsrLEENQrQQIESLTGAHQRKLDDVieaweKKLSQQAAELR 1056
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRE----------------------LEEKQ-NEIEKLKKENQSYKQEI-----KNLESQINDLE 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1057 DKHAEQMEEKEQglgeLRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKL 1136
Cdd:TIGR04523  398 SKIQNQEKLNQQ----KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1137 EADLGCSLSEKLSLQEELAE-----LKLLADKSQL--RVSELTGQVQAA---EKELQSCKSLHELSKKSLEDKSLNLKSL 1206
Cdd:TIGR04523  474 SRSINKIKQNLEQKQKELKSkekelKKLNEEKKELeeKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1207 L--EELASQLDSRCERTKALLEAKTNELVctSRDKADAILARLSQCQRhtaTVGEALLRRMGQVSELEAQLTQLTEEQRT 1284
Cdd:TIGR04523  554 LkkENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKK---DLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          570       580
                   ....*....|....*....|...
gi 1907199001 1285 LKSSFQQVTNQLEEKEKQIKTMK 1307
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIK 651
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 546-1662 5.46e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 5.46e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  546 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQES---KTQSEHL---------------AVHLE--------AE 599
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSihlEKEIKDLfdkyleiddeiiyinKLKLElkekikniSD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  600 KNKHNK---ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ--------- 667
Cdd:TIGR01612  615 KNEYIKkaiDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKenaidnted 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  668 -AHIQDMNEKTLEKLDKKQ-MELESVSSELSEALRARDQLAEELSvlrgdadKMKQALEAELeeqrrhhQREVGSISEQq 745
Cdd:TIGR01612  695 kAKLDDLKSKIDKEYDKIQnMETATVELHLSNIENKKNELLDIIV-------EIKKHIHGEI-------NKDLNKILED- 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  746 eltVRRAEKALKdelSRLGALLDERDEhLRERQARVQDLEAHL--QKSAGELQQALAKLDLLHSEQSAarEQAGAYEEQL 823
Cdd:TIGR01612  760 ---FKNKEKELS---NKINDYAKEKDE-LNKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKEYI--KTISIKEDEI 830

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  824 AQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL---------ERQRSELEEKVRSLAQLQDSqlKNST 894
Cdd:TIGR01612  831 FKIINEMKFMKDDFLNKVDKFINFENNCK---EKIDSEHEQFAELtnkikaeisDDKLNDYEKKFNDSKSLINE--INKS 905

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  895 VEKEQARQSLMEKEN-----------IILQMREEQAKEIEILKQTLSSKEESISIlHEEYETKFKN----QEKRMEKIKQ 959
Cdd:TIGR01612  906 IEEEYQNINTLKKVDeyikicentkeSIEKFHNKQNILKEILNKNIDTIKESNLI-EKSYKDKFDNtlidKINELDKAFK 984

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  960 KAK------EMQETKKKLLDQEAKLKKELENTVL-ELSQKEKQFNAQILEMAQANS----------AGISDTVSRLEENQ 1022
Cdd:TIGR01612  985 DASlndyeaKNNELIKYFNDLKANLGKNKENMLYhQFDEKEKATNDIEQKIEDANKnipnieiaihTSIYNIIDEIEKEI 1064

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1023 RQQIESLTGAHQRKLDDVIEAWEK--------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKE---- 1090
Cdd:TIGR01612 1065 GKNIELLNKEILEEAEINITNFNEikeklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKseny 1144

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1091 VARLKEAVSG-QDVALAGLQGQ----LEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE----------ELA 1155
Cdd:TIGR01612 1145 IDEIKAQINDlEDVADKAISNDdpeeIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygkNLG 1224

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1156 ELKLLADKSQLRVSELTgqVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCT 1235
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHM--IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1236 SRDKADAIL-----------------ARLSQCQRHTATVGEAL-----LRRMGQVSELEAQLTQLTEEQRTLKSSFQQVT 1293
Cdd:TIGR01612 1303 IREKSLKIIedfseesdindikkelqKNLLDAQKHNSDINLYLneianIYNILKLNKIKKIIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1294 NQLEEKEKQIKTMKAD---------IEGLLTEK---EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLRE-ELS 1360
Cdd:TIGR01612 1383 DELDKSEKLIKKIKDDinleeckskIESTLDDKdidECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNiEMA 1462

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1361 EKKSE-IASLSKQ--LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKeKMSALEqvdhWSN 1437
Cdd:TIGR01612 1463 DNKSQhILKIKKDnaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLN-KYSALA----IKN 1537

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1438 KFSEWKKKAQSRLAQhqstIKDLQAQLDVKATDAREKEEQIcllkedldrqnkKFECLKGEMEVRKS-KMEKKECDLETA 1516
Cdd:TIGR01612 1538 KFAKTKKDSEIIIKE----IKDAHKKFILEAEKSEQKIKEI------------KKEKFRIEDDAAKNdKSNKAAIDIQLS 1601

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1517 LKTQTARVVELEDCVTQRK---KEVESLNETLKNYN-QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETvlrlrehvs 1592
Cdd:TIGR01612 1602 LENFENKFLKISDIKKKINdclKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK--------- 1672

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199001 1593 sleaelgtvKKELEHVNSSVKSRDGELKALEDKLELESAAKV-ELKRKAEQKIAAIRKQLLSQMEEKTQRY 1662
Cdd:TIGR01612 1673 ---------KKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIkEIAIANKEEIESIKELIEPTIENLISSF 1734
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1167-1695 1.87e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1167 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1237
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1238 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1317
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1318 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1397
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1398 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1477
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1478 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1554
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1555 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1629
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001 1630 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 664-888 1.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  664 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISE 743
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-RALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  744 QQElTVRRAEKALKDELSRLGALLderdehlrERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 823
Cdd:COG4942     91 EIA-ELRAELEAQKEELAELLRAL--------YRLGRQPPLALLL--SPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001  824 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS 888
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 554-903 2.23e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 53.42  E-value: 2.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  554 ENKLQELGQEAEAYRTRILELETSLEK--SLQESKTQ--SEHLAVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQdslw 629
Cdd:COG3096    784 EKRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvGGHLAVAFAPDP----EAELAALRQRRSELERELAQH---- 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  630 terlQSLSQQHQAAVEELREKyQQEKDALLKEKESLFQAHIQDMnektLEKLDKKQMELESVSSELSEALRARDQLAEEL 709
Cdd:COG3096    856 ----RAQEQQLRQQLDQLKEQ-LQLLNKLLPQANLLADETLADR----LEELREELDAAQEAQAFIQQHGKALAQLEPLV 926

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  710 SVLRGDA---DKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKALKDELSRLGALlDERDEHLRER-----QARV 781
Cdd:COG3096    927 AVLQSDPeqfEQLQADYLQAKEQQRRLKQQ----IFALSEVVQRRPHFSYEDAVGLLGEN-SDLNEKLRARleqaeEARR 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  782 QDLEAhLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSlltkqvvemETHKKHVCEELDAQ 861
Cdd:COG3096   1002 EAREQ-LRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERA---------RIRRDELHEELSQN 1071

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907199001  862 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 903
Cdd:COG3096   1072 RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQA 1113
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 755-981 2.56e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 834
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  835 TE----KSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENI 910
Cdd:COG4942     97 AEleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199001  911 ILQMREEQAKEIEILKQTLSSKEESISILheeyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKE 981
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARL----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1297-2092 2.86e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 2.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1297 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1372
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1373 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1452
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1453 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1532
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1533 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1612
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1613 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1692
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1693 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1770
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1771 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1850
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1851 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1930
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1931 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 2010
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2011 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2090
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907199001 2091 TK 2092
Cdd:pfam02463  962 NK 963
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1279-1491 3.07e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 3.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1279 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1358
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1359 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1427
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199001 1428 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1491
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1895-2138 3.25e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 3.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1895 EDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK------LSKEVARLQKELRALR-REHQQELDILKREcEQE 1967
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerykeLKAELRELELALLVLRlEELREELEELQEE-LKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1968 AEEKLKQEQEDLELKHTStLKQLMREFNtQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRR 2047
Cdd:TIGR02168  251 AEEELEELTAELQELEEK-LEELRLEVS-ELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2048 TARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTilELQTQLAQKTTLISDSKLKEQELREQVHN 2127
Cdd:TIGR02168  328 LESKLDE-LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--ELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250
                   ....*....|.
gi 1907199001 2128 LEDRLKRYEKN 2138
Cdd:TIGR02168  405 LEARLERLEDR 415
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
345-1002 3.31e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 3.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  345 DAKNLIEQLEQDKGMVITETKRQmLETLELKE--DEIAQLRSHIKQMTTQGEELREQKEKSERAAlyeqdwafEELEKAL 422
Cdd:PRK02224   173 DARLGVERVLSDQRGSLDQLKAQ-IEEKEEKDlhERLNGLESELAELDEEIERYEEQREQARETR--------DEADEVL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  423 STAQKTEDAQRRMKMEMDEQMKAVErASEEERLRLQHELSRVRQEAASMAKKNSEEQV-AALQKLHAEELASKEQELSRR 501
Cdd:PRK02224   244 EEHEERREELETLEAEIEDLRETIA-ETEREREELAEEVRDLRERLEELEEERDDLLAeAGLDDADAEAVEARREELEDR 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  502 LEARERELQEQmRIALEKSRSEYLKLTQEKEqqeslaleelelqkkailtesenklqELGQEAEAYRTRILELETSLEKS 581
Cdd:PRK02224   323 DEELRDRLEEC-RVAAQAHNEEAESLREDAD--------------------------DLEERAEELREEAAELESELEEA 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  582 LQESKTQSEHLAvhleaeknkhnkELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVE---ELREKYQQEKDAL 658
Cdd:PRK02224   376 REAVEDRREEIE------------ELEEEIEELRERFGDAPVDLGNA-EDFLEELREERDELREreaELEATLRTARERV 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  659 lKEKESLFQAHIQDMNEKTLEkldkkqmelesvSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEqrrhhqrev 738
Cdd:PRK02224   443 -EEAEALLEAGKCPECGQPVE------------GSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLER--------- 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  739 gsiSEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGA 818
Cdd:PRK02224   501 ---AEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  819 YEEQLAQMQQKVLDLETEKSLLtkqvvEMETHKKHVCEELDAQRAQVQQLERQR----SELEEKVRSL-AQLQDSQLKNS 893
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLL-----AAIADAEDEIERLREKREALAELNDERrerlAEKRERKRELeAEFDEARIEEA 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  894 TVEKEQARQSLMEKENIILQMREEQAKeieiLKQTLSSKEESIsilheeyetkfknqeKRMEKIKQKAKEMQETKKKL-- 971
Cdd:PRK02224   652 REDKERAEEYLEQVEEKLDELREERDD----LQAEIGAVENEL---------------EELEELRERREALENRVEALea 712

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1907199001  972 LDQEAklkKELENTVLELSQKEKQFNAQILE 1002
Cdd:PRK02224   713 LYDEA---EELESMYGDLRAELRQRNVETLE 740
PRK11281 PRK11281
mechanosensitive channel MscK;
741-1091 3.67e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.61  E-value: 3.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  741 ISEQQELTVrrAEKALKDELSRLGALLDERDEHlrerQARVQDLEAHLQKSAGELQQALAKLDLL-HSEQSAAREQAGAY 819
Cdd:PRK11281    48 LNKQKLLEA--EDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALkDDNDEETRETLSTL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  820 -----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL---------EEKVRSLAQL 885
Cdd:PRK11281   122 slrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGkvggkalrpSQRVLLQAEQ 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  886 QDSQLKNstvekEQARQSLmeKENIILQM-----REEQAKEIEILKQTLSSKEESISilheeyetkfknqEKRMEKIKQK 960
Cdd:PRK11281   202 ALLNAQN-----DLQRKSL--EGNTQLQDllqkqRDYLTARIQRLEHQLQLLQEAIN-------------SKRLTLSEKT 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  961 AKEMQETKKK-------LLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagISDTVSRLEENQRQQIESLTGA- 1032
Cdd:PRK11281   262 VQEAQSQDEAariqanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN-----WLDRLTQSERNIKEQISVLKGSl 336

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1033 --------HQRKL--DDVIeaweKKLSQQAAELRDKHAEQMEEKEQgLGELRQKV-RIVQSEKEELTKEV 1091
Cdd:PRK11281   337 llsrilyqQQQALpsADLI----EGLADRIADLRLEQFEINQQRDA-LFQPDAYIdKLEAGHKSEVTDEV 401
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1015-1695 3.77e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.43  E-value: 3.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1015 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 1091
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1092 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 1167
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1168 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1243
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1244 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1323
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1324 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1385
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1386 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1445
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1446 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1518
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1519 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1581
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1582 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1647
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199001 1648 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
COG5022 COG5022
Myosin heavy chain [General function prediction only];
285-915 4.33e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 52.39  E-value: 4.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  285 RQENLLQRCKETIGSHKEQCALllsEKEALQEQLDERLQELEK-MKELHMAEKTklITQLrdaKNLIEQLEQdkgmVITE 363
Cdd:COG5022    843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELES----EIIE 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  364 TKRQ----MLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEM 439
Cdd:COG5022    911 LKKSlssdLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKA 990

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  440 DEQMKAVERASEE---ERLRLQHELSRVRQEAASMAKKNSEEQV-----AALQKLhaeelaSKEQELSRRLEARERELQE 511
Cdd:COG5022    991 NSELKNFKKELAElskQYGALQESTKQLKELPVEVAELQSASKIissesTELSIL------KPLQKLKGLLLLENNQLQA 1064

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  512 QMRIALEKSRSEYLKLTQEKEQQESLALEELelqkkaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 591
Cdd:COG5022   1065 RYKALKLRRENSLLDDKQLYQLESTENLLKT-------INVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQ 1137

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  592 LAVHLEAEKNKHNKE---------LTALAEQHRTEVEGLQQQ----QDSLWTERLQSLSQQHQAAVEELREKYQQEKDAL 658
Cdd:COG5022   1138 LVNTLEPVFQKLSVLqleldglfwEANLEALPSPPPFAALSEkrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGW 1217

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  659 LKEKESL-FQAHIQDMNEkTLEKLDkkqmelESVSSELSEALRARDQLAEELSVLRGDADKMK-QALEAELEEQRRHHQR 736
Cdd:COG5022   1218 PRGDKLKkLISEGWVPTE-YSTSLK------GFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsYKLEEEVLPATINSLL 1290

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  737 EVGSISEQQELTVRRAEKALK--DELSRLGALLDERDehlreRQARVQDLEAHLQksagELQQALAKLDLLHSEQSAARE 814
Cdd:COG5022   1291 QYINVGLFNALRTKASSLRWKsaTEVNYNSEELDDWC-----REFEISDVDEELE----ELIQAVKVLQLLKDDLNKLDE 1361

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  815 qagayeeqLAQMQQKVLDLETEKSLLTKQVVEMETH-KKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDS----- 888
Cdd:COG5022   1362 --------LLDACYSLNPAEIQNLKSRYDPADKENNlPKEILKKIEALLIK----QELQLSLEGKDETEVHLSEIfseek 1429

                          650       660       670
                   ....*....|....*....|....*....|...
gi 1907199001  889 ---QLKNSTVEKEQARQSLME---KENIILQMR 915
Cdd:COG5022   1430 sliSLDRNSIYKEEVLSSLSAlltKEKIALLDR 1462
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 331-663 4.50e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 4.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  331 LHMAEKTKLITQlRDAKNLIEQLEQDKGMVITETK-RQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALY 409
Cdd:pfam17380  275 LHIVQHQKAVSE-RQQQEKFEKMEQERLRQEKEEKaREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERI 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  410 EQdwafEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAE 489
Cdd:pfam17380  354 RQ----EERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAE 428

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  490 ELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYRT 569
Cdd:pfam17380  429 QEEARQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERKQ 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  570 RILELETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELRE 649
Cdd:pfam17380  507 AMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMERERE 576

                          330
                   ....*....|....
gi 1907199001  650 KYQQEKDALLKEKE 663
Cdd:pfam17380  577 MMRQIVESEKARAE 590
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1896-2138 4.93e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1896 DRPEENSQSHEIQSNVGTVDGLRSDLESkltgaERDKQKLSKEVARLQKELRALRRE---HQQELDILKRECEQEAEEKL 1972
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERlaeLEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1973 KQEQEDLELKHTstlkqlmrefntQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRY 2052
Cdd:COG4913    294 EAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2053 EEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDsvtilELQTQLAqkttlisDSKLKEQELREQVHNLEDRL 2132
Cdd:COG4913    362 AR-LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-----ALEEALA-------EAEAALRDLRRELRELEAEI 428


                   ....*.
gi 1907199001 2133 KRYEKN 2138
Cdd:COG4913    429 ASLERR 434
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
618-867 5.36e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  618 VEGLQQQQDSLwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLF--------QAHIQDmNEKTLEKLDKKQMELE 689
Cdd:COG4913    612 LAALEAELAEL-EEELAEAEER-LEALEAELDALQERREALQRLAEYSWdeidvasaEREIAE-LEAELERLDASSDDLA 688

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  690 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDelsrlgALLDE 769
Cdd:COG4913    689 ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAA------ALGDA 762

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  770 RDEHLRER-QARVQDLEAHLQKSAGELQQALAKL----DLLHSEQSAAREQAGAYEEQLAQMQQKVL-DLETE-KSLLTK 842
Cdd:COG4913    763 VERELRENlEERIDALRARLNRAEEELERAMRAFnrewPAETADLDADLESLPEYLALLDRLEEDGLpEYEERfKELLNE 842

                          250       260
                   ....*....|....*....|....*
gi 1907199001  843 QvveMETHKKHVCEELDAQRAQVQQ 867
Cdd:COG4913    843 N---SIEFVADLLSKLRRAIREIKE 864
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 652-1684 5.38e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.10  E-value: 5.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  652 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 731
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  732 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 811
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  812 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 891
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  892 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 971
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  972 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLE---------ENQRQQIESLTGA 1032
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEqakrnkanlEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1033 HQRKLDDV------IEAWEKKLSQQAAELRDKHAE---QMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDV 1103
Cdd:pfam01576  389 LQAELRTLqqakqdSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1104 ALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 1183
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1184 SCKSLHELSKKSLEDKSLNLKSL----------LEELASQLDSRCERTKAL---------LEAKTNELVCTSRDKADAIL 1244
Cdd:pfam01576  549 RLQRELEALTQQLEEKAAAYDKLektknrlqqeLDDLLVDLDHQRQLVSNLekkqkkfdqMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1245 ARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEG 1324
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1325 GQQRQAASEKESCITQLKKELAENINAvtllREELSEKKSEiaSLSKQLSDLGAQLESsiSPSDKAEAISALSKqheeqe 1404
Cdd:pfam01576  709 QATEDAKLRLEVNMQALKAQFERDLQA----RDEQGEEKRR--QLVKQVRELEAELED--ERKQRAQAVAAKKK------ 774

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1405 lqLQAQLQELSLKVDALSKEKMSALEQVdhwsnkfsewkKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEE-------Q 1477
Cdd:pfam01576  775 --LELDLKELEAQIDAANKGREEAVKQL-----------KKLQAQMKDLQRELEEARASRDEILAQSKESEKklknleaE 841

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1478 ICLLKEDL---DRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT 1554
Cdd:pfam01576  842 LLQLQEDLaasERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQ 921

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1555 EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREhvssleaELGTVKKELEhvnSSVKSRDGELKALEDKLELES---A 1631
Cdd:pfam01576  922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQE-------MEGTVKSKFK---SSIAALEAKIAQLEEQLEQESrerQ 991

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 1632 AKVELKRKAEQKIaairKQLLSQME------EKTQRYAKDTENRLSELSAQLKEREKQV 1684
Cdd:pfam01576  992 AANKLVRRTEKKL----KEVLLQVEderrhaDQYKDQAEKGNSRMKQLKRQLEEAEEEA 1046
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1449-2138 6.20e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 6.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1449 RLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELE 1528
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1529 DCVTQRKKEVESLNETLKNYNQQR-----------DTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAE 1597
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEqlrvkekigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1598 LGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRkaEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQL 1677
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD--ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1678 KEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDctHKACKERLCMLQRRLSEKEKLLRRLEQGEG 1757
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--LYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1758 EARPSQPE-------------------------------AQHRALSGKL---------DCTRARQLEDHVLIGCLPEELE 1797
Cdd:TIGR02169  501 ASEERVRGgraveevlkasiqgvhgtvaqlgsvgeryatAIEVAAGNRLnnvvveddaVAKEAIELLKRRKAGRATFLPL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1798 EKMKCSLIVSQPMGEETGNNTGV-----KQNWASVVDSV-QKTLQEKELTC---QALEQRVKELESDLVRERGA------ 1862
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVdlvefDPKYEPAFKYVfGDTLVVEDIEAarrLMGKYRMVTLEGELFEKSGAmtggsr 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1863 --HRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVA 1940
Cdd:TIGR02169  661 apRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1941 RLQKELRALRRE---HQQELDILKRECE--QEAEEKLKQEQEDLElkhtstlKQLMREFNTQLAQKEQELERTVQETIDK 2015
Cdd:TIGR02169  741 ELEEDLSSLEQEienVKSELKELEARIEelEEDLHKLEEALNDLE-------ARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2016 AQEVEAELLESHQEEtQQLHRKIAEKEDDLRRTARRYEEIlDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSV 2095
Cdd:TIGR02169  814 LREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLKEQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199001 2096 TILE-----LQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 2138
Cdd:TIGR02169  892 DELEaqlreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 603-1231 7.77e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 51.38  E-value: 7.77e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  603 HNKELTALAEQHRTEVEGLQQQQDSLWTERLQ-SLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 681
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRlSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  682 DKKQMELESVSSELSEALRARDQ----LAEELSVLRGDADKMKQaLEAELEEQRRHHQREVGSISEQQELTVRRaEKALK 757
Cdd:pfam12128  308 GELSAADAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRR-RSKIK 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  758 DELSRLGALLDERDEHLRERQARVQDL-EAHLQKSAGELQqalaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETE 836
Cdd:pfam12128  386 EQNNRDIAGIKDKLAKIREARDRQLAVaEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  837 KSLLTKQVVEMEThKKHVCEELDAQRAQVQQLERQRSELeekvRSLAQLQDSQLKNSTVEKEQARQSLMEKE-------- 908
Cdd:pfam12128  460 PELLLQLENFDER-IERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALDELElqlfpqag 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  909 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL- 987
Cdd:pfam12128  535 TLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALq 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  988 -----------ELSQKEKQFNAQILEMAQANSA--GISDTVSRLEENQRQ---QIESLTGAHQRKLDDVIEAWEKKLSQQ 1051
Cdd:pfam12128  615 sarekqaaaeeQLVQANGELEKASREETFARTAlkNARLDLRRLFDEKQSekdKKNKALAERKDSANERLNSLEAQLKQL 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1052 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSA-----------VIV 1120
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA---QLALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdVIA 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1121 SLSERESQLQSQVEKLEADLGCSLSEKLSLQEE--LAELKLLADKSQLR--VSELTGQVQAAEKELQSCKSLHELSKKSL 1196
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLRYFDWYQETwlQRRPRLATQLSNIEraISELQQQLARLIADTKLRRAKLEMERKAS 851

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1907199001 1197 EDkslnLKSLLEELASQLDSRCERTKALLEAKTNE 1231
Cdd:pfam12128  852 EK----QQVRLSENLRGLRCEMSKLATLKEDANSE 882
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 816-1054 8.52e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  816 AGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNST 894
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  895 VEKEQARQSLMEKENIILQMREEQAKEIEILkqtLSSKEESISILHEEYETKF-KNQEKRMEKIKQKAKEMQETKKKLLD 973
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  974 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAA 1053
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKE---------LAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241


                   .
gi 1907199001 1054 E 1054
Cdd:COG4942    242 R 242
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2165-2204 1.60e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.88  E-value: 1.60e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907199001 2165 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 2204
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 278-899 1.62e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 1.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  278 MLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD---ERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLE 354
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEiiqEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMY 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  355 QDKgmvITETKRQMLetleLKEDEIAQLRSHIKQMTTQGEELREQKEKSeRAALYEQdwafeelEKALSTAQKTEDAQRR 434
Cdd:pfam15921  341 EDK---IEELEKQLV----LANSELTEARTERDQFSQESGNLDDQLQKL-LADLHKR-------EKELSLEKEQNKRLWD 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  435 MKMEMDEQMKAVERASEEERLRLQhELSRVRQEAASMAKKNSEEQVAALQKlhAEELASKEQELSRRLEARerelQEQMR 514
Cdd:pfam15921  406 RDTGNSITIDHLRRELDDRNMEVQ-RLEALLKAMKSECQGQMERQMAAIQG--KNESLEKVSSLTAQLEST----KEMLR 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  515 IALEKSRSEylKLTQEKEQQEslaleelelqkkaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQE---SKTQSEH 591
Cdd:pfam15921  479 KVVEELTAK--KMTLESSERT--------------VSDLTASLQEKERAIEATNAEITKLRSRVDLKLQElqhLKNEGDH 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  592 LAvHLEAEKNKHNKELTalaeQHRTEVEGLQQQQDSLwterLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQ 671
Cdd:pfam15921  543 LR-NVQTECEALKLQMA----EKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  672 DMNEKTLEKLDKKQMELESVSSEL----SEALRA-------RDQLAEELSVLRGDADKMKQALEAeleeqrrhHQREVGS 740
Cdd:pfam15921  614 DKKDAKIRELEARVSDLELEKVKLvnagSERLRAvkdikqeRDQLLNEVKTSRNELNSLSEDYEV--------LKRNFRN 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  741 ISEQQELTVRRAEKALKDELSRLgallderdEHLRERQARVQDLEAHLQKSA-GELQQALAKLDLLHSEQSAAReqagAY 819
Cdd:pfam15921  686 KSEEMETTTNKLKMQLKSAQSEL--------EQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQ----FL 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  820 EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlAQLQDSQLKNSTVEKEQ 899
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDK-ASLQFAECQDIIQRQEQ 832
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 704-1335 1.64e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 50.35  E-value: 1.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  704 QLAEELSVLRGDADKMKQALEAELEEQRRHHQ--REVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 781
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  782 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAyeEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 861
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL--LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  862 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQArqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHE 941
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL---AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  942 EYETK-FKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnAQILEMAQANSAGISDTVSRLEE 1020
Cdd:TIGR00618  465 AQSLKeREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD--IDNPGPLTRRMQRGEQTYAQLET 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1021 ----------NQRQQIESLTGAHQRKLDDVIEAWEK---------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQ 1081
Cdd:TIGR00618  543 seedvyhqltSERKQRASLKEQMQEIQQSFSILTQCdnrskedipNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1082 SE--KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcsLSEKLSLQEELAELKL 1159
Cdd:TIGR00618  623 PEqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA-----LQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1160 LADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsrdk 1239
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA----- 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1240 ADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQ--------LTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1311
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650       660
                   ....*....|....*....|....
gi 1907199001 1312 GLLTEKEALQQEGGQQRQAASEKE 1335
Cdd:TIGR00618  853 KYEECSKQLAQLTQEQAKIIQLSD 876
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 941-1140 1.85e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  941 EEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEE 1020
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-IAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1021 NQRQQIESLTGAHQRKLDDVIE---------------AWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKE 1085
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLAlllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001 1086 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADL 1140
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 303-984 2.38e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.97  E-value: 2.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  303 QCALLLSEKEALQEQLDERLQELEKMKELhmAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQML-ETLELKEDEIAQ 381
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQL--ALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYhERKQVLEKELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  382 LRSHIKQMTTQGEELREQKEKSERAALYEQD--WAFEELEKALSTAQKTEDAQRRMKMEMD-EQMKAVERASEEERLRLQ 458
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKaAPLAAHIKAVTQIEQQAQ 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  459 HELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLK---LTQEKEQQE 535
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhiHTLQQQKTT 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  536 SLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKhNKELTALAEQHR 615
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLE-KIHLQESAQSLK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  616 TEVEGLQQQQDSLwterlqsLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMnektlekldkkqMELESVSSEL 695
Cdd:TIGR00618  470 EREQQLQTKEQIH-------LQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI------------DNPGPLTRRM 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  696 SEALRARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLR 775
Cdd:TIGR00618  531 QRGEQTYAQLETSE-----------EDVYHQLTSERKQRASL-----KEQMQEIQQSFSILTQCDNRSKEDIPNLQNITV 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  776 ERQARVQDLEAHLQKSAGELQQALAKLdllhsEQSAAREQAGAYEEQLAQMQQKvldletekSLLTKQVVEMETHKKHVC 855
Cdd:TIGR00618  595 RLQDLTEKLSEAEDMLACEQHALLRKL-----QPEQDLQDVRLHLQQCSQELAL--------KLTALHALQLTLTQERVR 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  856 EELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEES 935
Cdd:TIGR00618  662 EHALSIRVLPKELLASRQLALQKMQSEKE-QLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDA 740

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199001  936 ISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEN 984
Cdd:TIGR00618  741 LNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQF 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
748-1362 2.83e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 2.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  748 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 827
Cdd:COG4913    236 DLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  828 QKVLDLETEKSLLTKQvvemetHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqLKNSTVEKEQARQSLmek 907
Cdd:COG4913    316 ARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPASAEEF--- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  908 eniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEnTVL 987
Cdd:COG4913    383 --------AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA-EAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  988 ELSQKEKQFNAQILEmaqansagisdtVSRLEENQRQQIESLTGAH-------QRKLDDVIEA-----WEKKLSQQAAEL 1055
Cdd:COG4913    454 GLDEAELPFVGELIE------------VRPEEERWRGAIERVLGGFaltllvpPEHYAAALRWvnrlhLRGRLVYERVRT 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1056 RDKHAEQMEEKEQGLGElrqKVRIVQSE-----KEELTKEVARLK----EAVSGQDVALAgLQGQLEQKSAV----IVSL 1122
Cdd:COG4913    522 GLPDPERPRLDPDSLAG---KLDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRAIT-RAGQVKGNGTRhekdDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1123 SERESQL-QSQVEKLEAdlgcslseklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSkksleDKSL 1201
Cdd:COG4913    598 IRSRYVLgFDNRAKLAA-----------LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS-----WDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1202 NLKSLLEELASqldsrcertkalLEAKTNELvctsrDKADAILARLSQcqrhtatvgeallrrmgQVSELEAQLTQLTEE 1281
Cdd:COG4913    662 DVASAEREIAE------------LEAELERL-----DASSDDLAALEE-----------------QLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1282 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSE 1361
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787


                   .
gi 1907199001 1362 K 1362
Cdd:COG4913    788 E 788
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 639-998 4.16e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 4.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  639 QHQAAVEElreKYQQEKdallkeKESLFQAHIQDMNEKTLEKLDKKQmelesvssELSEALRARDQLAEELSVLRGDADK 718
Cdd:pfam17380  279 QHQKAVSE---RQQQEK------FEKMEQERLRQEKEEKAREVERRR--------KLEEAEKARQAEMDRQAAIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  719 MKQALEAELEEQRRHHQREVGSISEQQELTVrraEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 798
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAM---EISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  799 LAKLDLLHSEQSAAReqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELdaqRAQVQQLERQRSELEEK 878
Cdd:pfam17380  419 KVEMEQIRAEQEEAR-------------QREVRRLEEERAREMERVRLEEQERQQQVERL---RQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  879 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqMREEQAKEIeilkqtlsskEESISILHEEYETKFKNQEKRMEKIK 958
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEER----KRKLLEKEM----------EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1907199001  959 QKAKEMQETKKKLLDQEAKL-----KKELENTVLELSQKEKQFNA 998
Cdd:pfam17380  549 EERRRIQEQMRKATEERSRLeamerEREMMRQIVESEKARAEYEA 593
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
748-1232 4.79e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  748 TVRRAEKALKDELSRLG---ALLDERDEHLRERQARVQDLEAHLQKSAGELQQA---LAKLDLLHSEQSAAREQAGAYEE 821
Cdd:PRK03918   173 EIKRRIERLEKFIKRTEnieELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  822 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEKVRSLAQLQD--SQLKNSTVEKEQ 899
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSrlEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  900 ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK 979
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  980 KELENTVLELSQKEKQFNA---------------------QILEMAQANSAGISDTVSRLEENQRQQIESLTGAH----- 1033
Cdd:PRK03918   412 ARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkk 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1034 ------QRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSE---KEELTKEVARLKEAVSGQDVA 1104
Cdd:PRK03918   492 eselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1105 LAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1184
Cdd:PRK03918   572 LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199001 1185 CKSL-----HELSKKSLEDKSLNLKSLLEELaSQLDSRCERTKALLEAKTNEL 1232
Cdd:PRK03918   652 LEKKyseeeYEELREEYLELSRELAGLRAEL-EELEKRREEIKKTLEKLKEEL 703
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
946-1547 5.09e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 5.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqilemaqansagisdtVSRLEENQRQQ 1025
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE-------------------INEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1026 IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKeqgLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVAL 1105
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---IRELEERIEELKKEIEELEEKVKELKE-LKEKAEEY 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1106 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSC 1185
Cdd:PRK03918   296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1186 KSLHELSKKSLEDKSLNLKSLLEELasqldsrcERTKALLEAKTNElvctsrdkadaILARLSQCQRHTATVGEALLRRM 1265
Cdd:PRK03918   372 EELERLKKRLTGLTPEKLEKELEEL--------EKAKEEIEEEISK-----------ITARIGELKKEIKELKKAIEELK 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1266 GQVSELEAQLTQLTEEQRtlKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEscITQLKKEL 1345
Cdd:PRK03918   433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1346 AENINAVTLlrEELSEKKSEIASLSKQLSDLGAQLESSispSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEK 1425
Cdd:PRK03918   509 EEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSL---KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1426 MSALEQVDHWSNKFSEWKKKaQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK-S 1504
Cdd:PRK03918   584 FESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyE 662

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907199001 1505 KMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1547
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 645-1431 5.20e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.81  E-value: 5.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  645 EELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELES---VSSELSEALRARDQLAEELSVLRGDADKMKQ 721
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyllYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  722 ALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGAL-LDERDEHLRERQARVQDLEAHLQKSAGELQQALA 800
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLkLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  801 KLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVR 880
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  881 SLAQLqdsqLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQK 960
Cdd:pfam02463  419 DLLKE----EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  961 AKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRK---- 1036
Cdd:pfam02463  495 LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALtelp 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1037 ---------LDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1107
Cdd:pfam02463  575 lgarklrllIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1108 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKS 1187
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1188 LHEL--------SKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTATVGE 1259
Cdd:pfam02463  735 NEELkllkqkidEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1260 ALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ--RQAASEKESC 1337
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQklKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1338 ITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLK 1417
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810
                   ....*....|....
gi 1907199001 1418 VDALSKEKMSALEQ 1431
Cdd:pfam02463  975 VNLMAIEEFEEKEE 988
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
144-816 6.25e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 6.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  144 RSLSSYRGKYSELVTAFQTLQREKKKLQGILSQSQdkslrRISELREELQMDQQAKKHLQDEFDA-CLEEKDQYISVLQT 222
Cdd:COG4913    228 DALVEHFDDLERAHEALEDAREQIELLEPIRELAE-----RYAAARERLAELEYLRAALRLWFAQrRLELLEAELEELRA 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  223 QVSLLKQRLQngpmnvdapkplppgELQAEvHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKETIGSHKE 302
Cdd:COG4913    303 ELARLEAELE---------------RLEAR-LDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  303 QCALL-----LSEKE--ALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQdkgmvitetkrqmletlelk 375
Cdd:COG4913    367 LLAALglplpASAEEfaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-------------------- 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  376 edEIAQLRSHIKQMTTQGEELREQKEksERAALYEQDWAF--EELEkalstaQKTEDAQRRMKMEM------------DE 441
Cdd:COG4913    427 --EIASLERRKSNIPARLLALRDALA--EALGLDEAELPFvgELIE------VRPEEERWRGAIERvlggfaltllvpPE 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  442 QMKAVERASEEERLRLQHELSRVRQEAAsmakknSEEQVAALQKLHAEELASKEQELSRRLEAR------------EREL 509
Cdd:COG4913    497 HYAAALRWVNRLHLRGRLVYERVRTGLP------DPERPRLDPDSLAGKLDFKPHPFRAWLEAElgrrfdyvcvdsPEEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  510 -QEQMRIALE---KSRSEylklTQEKEQQESLALE----ELELQKKAILtesENKLQELGQEAEAYRTRILELETSLEkS 581
Cdd:COG4913    571 rRHPRAITRAgqvKGNGT----RHEKDDRRRIRSRyvlgFDNRAKLAAL---EAELAELEEELAEAEERLEALEAELD-A 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  582 LQESKTQSEHLAVHLEAEKNkhnkeltalAEQHRTEVEGLQQQQDSLWTE--RLQSLSQQHQAAVEELREkYQQEKDALL 659
Cdd:COG4913    643 LQERREALQRLAEYSWDEID---------VASAEREIAELEAELERLDASsdDLAALEEQLEELEAELEE-LEEELDELK 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  660 KEKESLFQAHIQdmnekTLEKLDKKQMELESVSSELSEALRARdqLAEELSVLRGDADkmKQALEAELEEQRRHHQREVG 739
Cdd:COG4913    713 GEIGRLEKELEQ-----AEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAV--ERELRENLEERIDALRARLN 783

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001  740 SISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQA-RVQDLEAHLQKSAGEL-QQALAKLDLLHSEQSAAREQA 816
Cdd:COG4913    784 RAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRlEEDGLPEYEERFKELLnENSIEFVADLLSKLRRAIREI 862
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 898-1041 6.26e-05

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 48.12  E-value: 6.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  898 EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAK 977
Cdd:pfam10168  553 DLAREEIQKRVKLLKLQKEQQLQELQSLEEERKSLSERAEKLAEKYEEIKDKQEKLMRRCKKVLQRLNSQLPVLSDAERE 632

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199001  978 LKKELE--NTVLE-----LSQKEKQFNAQILEMAQANSAGISDTVSrLEENQRQQIESLTGAHQRKLDDVI 1041
Cdd:pfam10168  633 MKKELEtiNEQLKhlanaIKQAKKKMNYQRYQIAKSQSIRKKSSLS-LSEKQRKTIKEILKQLGSEIDELI 702
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
689-886 6.44e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.09  E-value: 6.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  689 ESVSSELSEALRARDQLAEELSVLRGDADkmkqALEAELEEQRRHHQreVGSISEQQELTVRRaekalkdeLSRLGALLD 768
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELE----EAEAALEEFRQKNG--LVDLSEEAKLLLQQ--------LSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  769 ERDEHLRERQARVQDLEAHLQKSAGE---------LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL 839
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199001  840 LTKQVVEMETHkkhvceELDAQRAQVQQLERQRSELEEKVRSLAQLQ 886
Cdd:COG3206    310 EAQRILASLEA------ELEALQAREASLQAQLAQLEARLAELPELE 350
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 301-954 6.45e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  301 KEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVitETKRQMLETLELKEDEIA 380
Cdd:TIGR00618  186 FAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL--TQKREAQEEQLKKQQLLK 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  381 QLRSHIKQMTTQGEELREQKEKSER----AALYEQDWAFEELEKALSTAQKT--EDAQRRMKMEMDEQMKAVERASEEER 454
Cdd:TIGR00618  264 QLRARIEELRAQEAVLEETQERINRarkaAPLAAHIKAVTQIEQQAQRIHTElqSKMRSRAKLLMKRAAHVKQQSSIEEQ 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  455 LRL------QHELSRVRQEAASMAKKNSEEQVAALQKLHA-----EELASKEQELSRRLEARERELQEQMRIALEKSRSE 523
Cdd:TIGR00618  344 RRLlqtlhsQEIHIRDAHEVATSIREISCQQHTLTQHIHTlqqqkTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQ 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  524 YLKLTQEKEQQESLALEELELQKKA-ILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLE-AEKN 601
Cdd:TIGR00618  424 GQLAHAKKQQELQQRYAELCAAAITcTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEP 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  602 KHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKD--ALLKEKESLFQAHIQDMNEK--- 676
Cdd:TIGR00618  504 CPLCGSCIHPNPARQDIDNPGPLTRRM--QRGEQTYAQLETSEEDVYHQLTSERKqrASLKEQMQEIQQSFSILTQCdnr 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  677 TLEKLDKKQMELESVSSELSEALRARDQLAEELSVLrgdadkMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAL 756
Cdd:TIGR00618  582 SKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL------LRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTL 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  757 KDELSRLGALLDERDE--HLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 834
Cdd:TIGR00618  656 TQERVREHALSIRVLPkeLLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLA 735

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  835 TEKSLLTKQVVEMETHKKHVCEELDAQRAQ------------------VQQLERQRSELEEKVRSLAQLQ---------D 887
Cdd:TIGR00618  736 AREDALNQSLKELMHQARTVLKARTEAHFNnneevtaalqtgaelshlAAEIQFFNRLREEDTHLLKTLEaeigqeipsD 815

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001  888 SQLKNSTVEK-----EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRM 954
Cdd:TIGR00618  816 EDILNLQCETlvqeeEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
mukB PRK04863
chromosome partition protein MukB;
285-967 6.53e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.41  E-value: 6.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  285 RQENLLQRCKETIGSHKEQcallLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRD-----------------AK 347
Cdd:PRK04863   345 RQQEKIERYQADLEELEER----LEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADyqqaldvqqtraiqyqqAV 420

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  348 NLIEQLEQDKGM--VITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKS---------ERAALYEQDWAFE 416
Cdd:PRK04863   421 QALERAKQLCGLpdLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAyqlvrkiagEVSRSEAWDVARE 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  417 ELEKALStaQKTEDAQRrmkmemdEQMKAvERASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASK 494
Cdd:PRK04863   501 LLRRLRE--QRHLAEQL-------QQLRM-RLSELEQRLRQQQRAERLLAEFCKRLGKnlDDEDELEQLQEELEARLESL 570

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  495 EQELSrrlEARERelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELElqkkaiLTESENKLQELGQEAEAYRTRILEL 574
Cdd:PRK04863   571 SESVS---EARER--RMALRQQLEQLQARIQRLAARAPAWLAAQDALAR------LREQSGEEFEDSQDVTEYMQQLLER 639

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  575 ETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE---LTALAEQHR----TEVEGLQQQQDSLWTERLqsLSQQHQAAV--- 644
Cdd:PRK04863   640 ERELTVERDELAARKQALDEEIERLSQPGGSEdprLNALAERFGgvllSEIYDDVSLEDAPYFSAL--YGPARHAIVvpd 717

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  645 -----EELREKYQQEKDALLKE------KESLFQAhiQDMNEKTLEKLDKKQMELESVSSE----------LSEALRA-R 702
Cdd:PRK04863   718 lsdaaEQLAGLEDCPEDLYLIEgdpdsfDDSVFSV--EELEKAVVVKIADRQWRYSRFPEVplfgraarekRIEQLRAeR 795

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  703 DQLAEELSVLRGDADKMKQALE----------------------AELEEQRRHHQREVGSIsEQQELTVRRAEKALKDEL 760
Cdd:PRK04863   796 EELAERYATLSFDVQKLQRLHQafsrfigshlavafeadpeaelRQLNRRRVELERALADH-ESQEQQQRSQLEQAKEGL 874

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  761 SRLGALLDE----RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQagayEEQLAQMQQKVLDLETE 836
Cdd:PRK04863   875 SALNRLLPRlnllADETLADRVEEIREQLDEAEEAKRFVQQHGNALAQLEPIVSVLQSD----PEQFEQLKQDYQQAQQT 950

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  837 KSLLTKQ------VVEMETH------KKHVCEELDAQ---RAQVQQLERQRSELEEKVR-SLAQLQD-----SQLKNSTV 895
Cdd:PRK04863   951 QRDAKQQafalteVVQRRAHfsyedaAEMLAKNSDLNeklRQRLEQAEQERTRAREQLRqAQAQLAQynqvlASLKSSYD 1030

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907199001  896 EKEQARQSLM-EKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 967
Cdd:PRK04863  1031 AKRQMLQELKqELQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERD 1103
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1440-2137 7.23e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.43  E-value: 7.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1440 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1519
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1520 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1599
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1600 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1677
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1678 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1752
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1753 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVsqPMGEETGNNTGVKQNWASVVDSVQ 1832
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAV--ENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1833 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYE-KSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNV 1911
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1912 GTVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 1989
Cdd:pfam02463  643 AKESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1990 LMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTD 2069
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 2070 LQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 2137
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
641-788 7.46e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.93  E-value: 7.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  641 QAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEElsvlrgdadkmk 720
Cdd:COG2433    379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELEEKDERIER------------ 445

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001  721 qaLEAELEEQRRhhqrevgsiSEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 788
Cdd:COG2433    446 --LERELSEARS---------EERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
754-1041 7.96e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 7.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  754 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 833
Cdd:COG4372     48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  834 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEKEQARQSLMEKENIIL 912
Cdd:COG4372    128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaEQALDELLKEANRNAEKEEELAEAEK 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 992
Cdd:COG4372    208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199001  993 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVI 1041
Cdd:COG4372    288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1936-2147 9.54e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1936 SKEVARLQKELRALRREHQQELDILKREceQEAEEKLKQEQEDLELKhTSTLKQLMREFNTQLAQKEQELERT------V 2009
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAAL--KKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELekeiaeL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2010 QETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARR---YEEILDAREEEMTG------KVTDLQTQLEELQKK 2080
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEElradlaELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 2081 YQQRLEQEESTKDSVT--ILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTP 2147
Cdd:COG4942    176 LEALLAELEEERAALEalKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 687-903 9.75e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 9.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  687 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQEltvrraekALKDELSRLGAL 766
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYN-ELQAELEALQAEIDKLQAEIA--------EAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  767 LDERDEHLRERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVE 846
Cdd:COG3883     88 LGERARALYRSGGSVSYLDVLL--GSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001  847 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 903
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 675-889 9.88e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  675 EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ---ALEAELEEQRRHHQREVGSISEQQELTVRR 751
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  752 AEKALK-DELSRLGALLDERD-EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAgayEEQLAQMQQK 829
Cdd:COG4942    110 LRALYRlGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL---EALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  830 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQ 889
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1116-1347 1.05e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1116 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 1195
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1196 LEDKSLNLKSLLeeLASQLDSRCERTKALLEAKtnelvctSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1275
Cdd:COG4942     99 LEAQKEELAELL--RALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001 1276 TQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEgllTEKEALQQEGGQQRQAASEKESCITQLKKELAE 1347
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
mukB PRK04863
chromosome partition protein MukB;
638-903 1.10e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  638 QQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALR-------ARDQLAEE 708
Cdd:PRK04863   847 VELERALADHESQEQQQRSQLeqAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRfvqqhgnALAQLEPI 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  709 LSVLRGDadkmkqalEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDelsrlgalLDERDEHLRERQArVQDLEAhl 788
Cdd:PRK04863   927 VSVLQSD--------PEQFEQLKQDYQQ-----AQQTQRDAKQQAFALTE--------VVQRRAHFSYEDA-AEMLAK-- 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  789 qksAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEME------------------- 848
Cdd:PRK04863   983 ---NSDLNEKLrQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKqelqdlgvpadsgaeerar 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001  849 THKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 903
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
274-744 1.13e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  274 KTLEMLQQRVKRQENLLQRCKETIGShKEQCALLLSEKEALQEQLDERLQELEKMKELHMaektkLITQLRDAKNLIEQL 353
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEE-LEELEEELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAELAEL 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  354 EQDKgmvitETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQR 433
Cdd:COG4717    145 PERL-----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  434 RMKMEMDEQMKAVERASEEERL--RLQHELSRVRQEAA-------SMAKKNSEEQVAALQKLHAEELASKEQELSRRLEA 504
Cdd:COG4717    220 EELEELEEELEQLENELEAAALeeRLKEARLLLLIAAAllallglGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  505 RERELQEQMRIAlEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE 584
Cdd:COG4717    300 LGKEAEELQALP-ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAE 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  585 SKTQSEhlavhleaeknkhnKELTALAEQHRTEVEglqqqqdslWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKES 664
Cdd:COG4717    379 AGVEDE--------------EELRAALEQAEEYQE---------LKEELEELEEQLEELLGELEELLEALDEEELEEELE 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  665 LFQAHIQDMNEKT---LEKLDKKQMELESVSS--ELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVG 739
Cdd:COG4717    436 ELEEELEELEEELeelREELAELEAELEQLEEdgELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLP 515


                   ....*
gi 1907199001  740 SISEQ 744
Cdd:COG4717    516 PVLER 520
PRK12704 PRK12704
phosphodiesterase; Provisional
 1932-2063 1.17e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 47.08  E-value: 1.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1932 KQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtQLAQKEQELERtvqe 2011
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907199001 2012 tidkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEM 2063
Cdd:PRK12704   101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 421-646 1.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  421 ALSTAQKTEDAQRRMKmEMDEQMKAVER---ASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEeLASKE 495
Cdd:COG4942     15 AAAQADAAAEAEAELE-QLQQEIAELEKelaALKKEEKALLKQLAALERRIAALARRirALEQELAALEAELAE-LEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  496 QELSRRLEARERELQEQMRIALEKSRSEYLK--LTQEKEQQESLALEELELQKKAILTESEnKLQELGQEAEAYRTRILE 573
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRLGRQPPLAllLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907199001  574 LETSLEKSLQESKTQSEHLAVhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEE 646
Cdd:COG4942    172 ERAELEALLAELEEERAALEA-LKAERQKLLARLEKELAELAAELAELQQEAEEL-EALIARLEAEAAAAAER 242
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 692-852 1.71e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 45.90  E-value: 1.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  692 SSELSEALRARDQLAEELSVLRGDAdkmkQALEAELEEQRRHHQREVGSISEQ------QELTVRRAEKALKDELSRLGA 765
Cdd:pfam09787   46 TLELEELRQERDLLREEIQKLRGQI----QQLRTELQELEAQQQEEAESSREQlqeleeQLATERSARREAEAELERLQE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  766 LLDERDEHLRE----RQARVQDLEAHLQKSAGELQQAlaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLT 841
Cdd:pfam09787  122 ELRYLEEELRRskatLQSRIKDREAEIEKLRNQLTSK----SQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLV 197

                          170
                   ....*....|.
gi 1907199001  842 KQVVEMETHKK 852
Cdd:pfam09787  198 LQLERMEQQIK 208
PTZ00121 PTZ00121
MAEBL; Provisional
 301-606 2.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 2.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  301 KEQCALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDkgmvitETKRQMLETLELKEDE-- 378
Cdd:PTZ00121  1573 EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA------EEEKKKVEQLKKKEAEek 1646

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  379 --IAQLRSHIKQMTTQGEELREQKEKSERAAlyeqdwafEELEKALSTAQKTEDAQRRmkmEMDEQMKAVE-RASEEERL 455
Cdd:PTZ00121  1647 kkAEELKKAEEENKIKAAEEAKKAEEDKKKA--------EEAKKAEEDEKKAAEALKK---EAEEAKKAEElKKKEAEEK 1715

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  456 RLQHELSR---VRQEAASMAKKNSEEqvaalQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSeylkLTQEKE 532
Cdd:PTZ00121  1716 KKAEELKKaeeENKIKAEEAKKEAEE-----DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV----IEEELD 1786

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199001  533 QQESLALEELELQKKAILTESENkLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE 606
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE 1859
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 319-1066 2.57e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.58  E-value: 2.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  319 DERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLELK----EDEIAQLRSHIKQMTTQGE 394
Cdd:TIGR00606  389 ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKkeilEKKQEELKFVIKELQQLEG 468

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  395 ELREQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlQHELSRVRQEAASMAKK 474
Cdd:TIGR00606  469 SSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLN---HHTTTRTQMEMLTKDKM 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  475 NSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESE 554
Cdd:TIGR00606  546 DKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  555 NKLQELGQeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQ 634
Cdd:TIGR00606  626 DKLFDVCG-SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKL 704

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  635 SLSQQHQAAVEELREKYQQEKDALLKEKESlfQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEEL----- 709
Cdd:TIGR00606  705 RLAPDKLKSTESELKKKEKRRDEMLGLAPG--RQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpeee 782

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  710 --SVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARvQDLEAH 787
Cdd:TIGR00606  783 saKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQ-QEQIQH 861

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  788 LQKSAGELQQALAKLdllhseqSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKhvceeldaqraQVQQ 867
Cdd:TIGR00606  862 LKSKTNELKSEKLQI-------GTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE-----------KDQQ 923

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  868 LERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLmekENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKF 947
Cdd:TIGR00606  924 EKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDI---ENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDM 1000

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  948 KNQEKRMEKIKQKAKEMQE--TKKKLLDQEAKLKKELENTVLELSQKekqfnaQILEMAQANsagisdtvSRLEENQRqq 1025
Cdd:TIGR00606 1001 RLMRQDIDTQKIQERWLQDnlTLRKRENELKEVEEELKQHLKEMGQM------QVLQMKQEH--------QKLEENID-- 1064

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1907199001 1026 iesLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEK 1066
Cdd:TIGR00606 1065 ---LIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEK 1102
PLN02939 PLN02939
transferase, transferring glycosyl groups
 753-976 2.66e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 2.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  753 EKALKDELSRLGALLDERDEHLR---ERQARVQDLEAHLQKSAGELQQALA-----------KLDLLHSEQSAAREQAGA 818
Cdd:PLN02939   165 KEALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteglcvhslskELDVLKEENMLLKDDIQF 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  819 YEEQLAQMQ---QKVLDLETEKSLLTKQVVEMEthkkhvCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSqlknSTV 895
Cdd:PLN02939   245 LKAELIEVAeteERVFKLEKERSLLDASLRELE------SKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDR----ATN 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  896 EKEQARQSLMEKENI--ILQMREEQAKE----------IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 963
Cdd:PLN02939   315 QVEKAALVLDQNQDLrdKVDKLEASLKEanvskfssykVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSK 394

                          250
                   ....*....|....
gi 1907199001  964 M-QETKKKLLDQEA 976
Cdd:PLN02939   395 LkEESKKRSLEHPA 408
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
753-1220 2.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 2.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  753 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ--KV 830
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  831 LDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKeni 910
Cdd:COG4717    128 LPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE--- 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  911 ilqmREEQAKEIEILKQTLSSKEESISILHEEYETkfknqekrmekiKQKAKEMQETKKKLldQEAKLKKELENTVLELS 990
Cdd:COG4717    201 ----LEELQQRLAELEEELEEAQEELEELEEELEQ------------LENELEAAALEERL--KEARLLLLIAAALLALL 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  991 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGL 1070
Cdd:COG4717    263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1071 GELRQKVRIVQSEKEELTKEvARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSL 1150
Cdd:COG4717    343 LDRIEELQELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001 1151 QEELAELKLLADKSQLR--VSELTGQVQAAEKELQSCKslHELSKKSLEDKSLNLKSLLEELASQLDSRCER 1220
Cdd:COG4717    422 LEALDEEELEEELEELEeeLEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEE 491
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 341-459 3.45e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 3.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  341 TQLRDAKNLIEQLEQDKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELRE--QKEKSERAALYEQDWAFEEL 418
Cdd:COG0542    411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWEAEKEliEEIQELKEELEQRYGKIPEL 490

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907199001  419 EKALSTAQKTEDAQRRM-KMEMDEQMKA----------VERASEEERLRLQH 459
Cdd:COG0542    491 EKELAELEEELAELAPLlREEVTEEDIAevvsrwtgipVGKLLEGEREKLLN 542
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1149-1389 3.50e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1149 SLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhelskKSLEDKSLNLKSLLEELASQLDSRcERTKALLEAK 1228
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQL-----------AALERRIAALARRIRALEQELAAL-EAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1229 TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLT---QLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1305
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1306 MKADIEGLLTEKEALQQEggqQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSIS 1385
Cdd:COG4942    172 ERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....
gi 1907199001 1386 PSDK 1389
Cdd:COG4942    249 AALK 252
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 686-796 3.79e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.84  E-value: 3.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  686 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvrrAEKALKDELSRLGA 765
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE-----AEKELIEEIQELKE 478

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1907199001  766 LLDERDEHLRERQARVQDLEAHLQKSAGELQ 796
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAPLLR 509
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-1141 3.88e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  294 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELhmaEKTKLITQLRDAKNLIEQLEQDKGMVITETKRQMLETLE 373
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  374 LKEDEIAQLRSHIKQMTTQGEELREQKEKSE--RAALYEQDWAFEELEKALSTAQKtEDAQRRMKME-----MDEQMKAV 446
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEK-DNSELELKMEkvfqgTDEQLNDL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  447 E-------RASEEERLRLQHELSRVRQEAASMAKKNSEEQV--------AALQKLHAEELASKEQELSRRLEA------- 504
Cdd:TIGR00606  307 YhnhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVeqgrlqlqADRHQEHIRARDSLIQSLATRLELdgfergp 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  505 -RERELQEQMRIALE------KSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQEL-------------GQEA 564
Cdd:TIGR00606  387 fSERQIKNFHTLVIErqedeaKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILekkqeelkfvikeLQQL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  565 EAYRTRILELETSLEKSLQESKTQSEHLAVH--LEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQA 642
Cdd:TIGR00606  467 EGSSDRILELDQELRKAERELSKAEKNSLTEtlKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  643 AVEELREKYQQEKDALL---------KEKESLFQAHIQDMNEkTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLr 713
Cdd:TIGR00606  547 KDEQIRKIKSRHSDELTsllgyfpnkKQLEDWLHSKSKEINQ-TRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY- 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  714 gdADKMKQALEAELEEQRRHHQREvgsiseqqeltvrRAEKALKDE--LSRLGALLDERDEHLRERQARVQDLEAHLQKS 791
Cdd:TIGR00606  625 --EDKLFDVCGSQDEESDLERLKE-------------EIEKSSKQRamLAGATAVYSQFITQLTDENQSCCPVCQRVFQT 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  792 AGELQQALAKLdllhseqsaareqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ 871
Cdd:TIGR00606  690 EAELQEFISDL------------------------QSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKE 745

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  872 RSELEEKVRSLAQlQDSQLKNSTVEKEQARQSLMEKENI---------ILQMREEQAKEIEILKQTLSSKEESISILHEE 942
Cdd:TIGR00606  746 IPELRNKLQKVNR-DIQRLKNDIEEQETLLGTIMPEEESakvcltdvtIMERFQMELKDVERKIAQQAAKLQGSDLDRTV 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  943 YETKFKNQEK--RMEKIKQKAKEMQetkkKLLDQEAKLKKELENTVLELsqkeKQFNAQILEMAQANSAGISDTVSRLEE 1020
Cdd:TIGR00606  825 QQVNQEKQEKqhELDTVVSKIELNR----KLIQDQQEQIQHLKSKTNEL----KSEKLQIGTNLQRRQQFEEQLVELSTE 896

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1021 NQRQQIESltgAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARlkeavsg 1100
Cdd:TIGR00606  897 VQSLIREI---KDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQD------- 966

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 1907199001 1101 qdvalaGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLG 1141
Cdd:TIGR00606  967 ------GKDDYLKQKETELNTVNAQLEECEKHQEKINEDMR 1001
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1908-2099 4.03e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 4.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1908 QSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTL 1987
Cdd:COG3206    204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELS 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1988 KQL------MREFNTQLAQKEQELERTVQETIDKAqEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEIldAREe 2061
Cdd:COG3206    284 ARYtpnhpdVIALRAQIAALRAQLQQEAQRILASL-EAELEALQAREASLQAQLAQLEARLAELPELEAELRRL--ERE- 359

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1907199001 2062 emtgkVTDLQTQLEELQKKYQQRLEQEESTKDSVTILE 2099
Cdd:COG3206    360 -----VEVARELYESLLQRLEEARLAEALTVGNVRVID 392
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1205-1381 4.14e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 4.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1205 SLLEELASQLDS-RCERTKALLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELE-AQLTQLTEEQ 1282
Cdd:COG4913    272 AELEYLRAALRLwFAQRRLELLEAELEEL----RAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1283 RTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitQLKKELAENINAVTLLREELSEK 1362
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE---ALEEALAEAEAALRDLRRELREL 424

                          170
                   ....*....|....*....
gi 1907199001 1363 KSEIASLSKQLSDLGAQLE 1381
Cdd:COG4913    425 EAEIASLERRKSNIPARLL 443
mukB PRK04863
chromosome partition protein MukB;
282-624 4.19e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 45.72  E-value: 4.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  282 RVKRQENLLQRCKETIGSHkeqCAL-LLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLeqdkgmv 360
Cdd:PRK04863   808 DVQKLQRLHQAFSRFIGSH---LAVaFEADPEAELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL------- 877

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  361 itetkRQMLETLELKEDEIAQLRShikqmttqgEELREQKEKSERAALY--EQDWAFEELEKALSTAQktedaqrrmkme 438
Cdd:PRK04863   878 -----NRLLPRLNLLADETLADRV---------EEIREQLDEAEEAKRFvqQHGNALAQLEPIVSVLQ------------ 931

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  439 mdeqmkavERASEEERLRLQHELSRVRQEAASM---AKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRI 515
Cdd:PRK04863   932 --------SDPEQFEQLKQDYQQAQQTQRDAKQqafALTEVVQRRAHFSYEDAAEMLAKNSDLNEKLRQRLEQAEQERTR 1003

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  516 ALEKSRSEYLKLTQEKeqQESLALEELELQKKAILTESENKLQELG-----QEAEAYRTRILELETSLEKSlQESKTQSE 590
Cdd:PRK04863  1004 AREQLRQAQAQLAQYN--QVLASLKSSYDAKRQMLQELKQELQDLGvpadsGAEERARARRDELHARLSAN-RSRRNQLE 1080

                          330       340       350
                   ....*....|....*....|....*....|....
gi 1907199001  591 HLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQ 624
Cdd:PRK04863  1081 KQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1933-2134 6.11e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 45.07  E-value: 6.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1933 QKLSKEVARLQKELRALR---REHQQELDILKRECEQEAEEKLKQ-EQEDLE-----LKHTSTLKQLMREFNTQLAQKEQ 2003
Cdd:COG0497    161 REAYRAWRALKKELEELRadeAERARELDLLRFQLEELEAAALQPgEEEELEeerrrLSNAEKLREALQEALEALSGGEG 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2004 ELERTVQETIDKAQEVE---------AELLESHQEETQqlhrkiaekedDLRRTARRYEEILDAREEEMTgKVTDLQTQL 2074
Cdd:COG0497    241 GALDLLGQALRALERLAeydpslaelAERLESALIELE-----------EAASELRRYLDSLEFDPERLE-EVEERLALL 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2075 EELQKKYQQRLEQeestkdsvtILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKR 2134
Cdd:COG0497    309 RRLARKYGVTVEE---------LLAYAEELRAELAELENSDERLEELEAELAEAEAELLE 359
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1512-2054 6.11e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1512 DLETALKTQTArvvELEDCVTQRKKEVESLNETlknynQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1591
Cdd:PRK02224   210 GLESELAELDE---EIERYEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1592 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIrKQLLSQMEEKTQRyAKDTENRLS 1671
Cdd:PRK02224   282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA-QAHNEEAESLRED-ADDLEERAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1672 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQeaPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1751
Cdd:PRK02224   360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD--LGNAEDFLEELREERDELREREAELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1752 LEQGEGEARPSQPEaqhralsGKldCTRARQ-LEDHVLIGCLPEELEEKMKCSLIVSQPmgEETGNNTGVKQNWASVVDS 1830
Cdd:PRK02224   438 ARERVEEAEALLEA-------GK--CPECGQpVEGSPHVETIEEDRERVEELEAELEDL--EEEVEEVEERLERAEDLVE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1831 VQKTLQEKELTCQALEQRVKElesdlvrergaHRLEVEKLTLKYEKSQSSQQEMDGEnkCVEVLEDRPEENSQSHEIQSN 1910
Cdd:PRK02224   507 AEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE--AEEKREAAAEAEEEAEEAREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1911 VGTVDGLRSDLESKLTGAERDKQKLSK-EVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 1989
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199001 1990 LMREFNTQLAQKEQELERTVQETIDKAQEVEAelLESHQEETQQLHRKIAEKEDDLRRTARRYEE 2054
Cdd:PRK02224   654 DKERAEEYLEQVEEKLDELREERDDLQAEIGA--VENELEELEELRERREALENRVEALEALYDE 716
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 282-619 6.19e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 45.33  E-value: 6.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  282 RVKRQENLLQRCKETIGSHKEQCalLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLeqdkgmvi 361
Cdd:COG3096    807 DVQKLQRLHQAFSQFVGGHLAVA--FAPDPEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLL-------- 876

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  362 tetkRQMLETLELKEDEIAQLRShikqmttqgEELREQKEKSERAALY--EQDWAFEELEKALSTAQKTEdaqrrmkmEM 439
Cdd:COG3096    877 ----NKLLPQANLLADETLADRL---------EELREELDAAQEAQAFiqQHGKALAQLEPLVAVLQSDP--------EQ 935

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  440 DEQMKAveraseeERLRLQHELSRVRQEAASMAKknSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEK 519
Cdd:COG3096    936 FEQLQA-------DYLQAKEQQRRLKQQIFALSE--VVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQ 1006

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  520 SRSEYLKLTQekEQQESLALEELELQKKAILTESENKLQELG----QEAEAY-RTRILELETSLEKSLQEsKTQSEHLAV 594
Cdd:COG3096   1007 LRQAQAQYSQ--YNQVLASLKSSRDAKQQTLQELEQELEELGvqadAEAEERaRIRRDELHEELSQNRSR-RSQLEKQLT 1083

                          330       340
                   ....*....|....*....|....*
gi 1907199001  595 HLEAEKNKHNKELTALAEQHRTEVE 619
Cdd:COG3096   1084 RCEAEMDSLQKRLRKAERDYKQERE 1108
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 305-534 6.71e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  305 ALLLSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDkgmvITETKRQmletLELKEDEIAQLRS 384
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQE----LAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  385 HIKQMTTQGEELREQKEKSERAAlyeQDWAFEELEKALSTAQKTEDAQRRMKMemdeqMKAVERASEEERLRLQHELSRV 464
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRAL---YRLGRQPPLALLLSPEDFLDAVRRLQY-----LKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199001  465 RQEAASMAKKNSE------EQVAALQKLhaEELASKEQELSRRLEARERELQEQMRiALEKSRSEYLKLTQEKEQQ 534
Cdd:COG4942    163 AALRAELEAERAEleallaELEEERAAL--EALKAERQKLLARLEKELAELAAELA-ELQQEAEELEALIARLEAE 235
PRK09039 PRK09039
peptidoglycan -binding protein;
1073-1214 7.11e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 7.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1073 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE 1152
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001 1153 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKslEDKSLNLKslLEELASQL 1214
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK--RDRESQAK--IADLGRRL 181
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 794-1012 7.46e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 7.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  794 ELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 873
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  874 ELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKR 953
Cdd:COG3883     97 RSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001  954 MEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGIS 1012
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
574-1009 7.98e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 7.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  574 LETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRtEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQ 653
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE-EYAELQEELEEL-EEELEELEAELEELREELEKLEKL 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  654 EKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRH 733
Cdd:COG4717    125 LQLLPLYQELEALEAELAELPER-LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  734 HQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV--------------QDLEAHLQKSAGELQQAL 799
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLlliaaallallglgGSLLSLILTIAGVLFLVL 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  800 AKLDLLHSEQSAAREQAGA-YEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEK 878
Cdd:COG4717    284 GLLALLFLLLAREKASLGKeAEELQALPALEELEEEELEELLAALGLPPDLSPEEL-LELLDRIEELQELLREAEELEEE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  879 VR--SLAQLQDSQLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESISILHEEYEtkFKNQEKRMEK 956
Cdd:COG4717    363 LQleELEQEIAALLAEAGVEDEEELRAALEQ----AEEYQELKEELEELEEQLEELLGELEELLEALD--EEELEEELEE 436

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001  957 IKQKAKEMQETKKKLLDQEAKLKKELE-----NTVLELSQKEKQFNAQILEMAQANSA 1009
Cdd:COG4717    437 LEEELEELEEELEELREELAELEAELEqleedGELAELLQELEELKAELRELAEEWAA 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 948-1184 8.62e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  948 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqiLEMAQANSAGISDTVSRLEENQRQQIE 1027
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1028 SLTgAHQRKLDDVIEAWEKKLSQQAAELRdKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 1107
Cdd:COG4942     98 ELE-AQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001 1108 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 1184
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELA-------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
mukB PRK04863
chromosome partition protein MukB;
695-1154 9.41e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.56  E-value: 9.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  695 LSEALRARDQLAEELSVLRGDADKMKQALEAEL----------EEQRRHHQREVGSIseQQELTvrRAEKALKDELSRLG 764
Cdd:PRK04863   235 MEAALRENRMTLEAIRVTQSDRDLFKHLITESTnyvaadymrhANERRVHLEEALEL--RRELY--TSRRQLAAEQYRLV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  765 ALLDERDEHLRERQARVQDLEA---HL---------QKSAGELQQALAKLDLLHSEQSAAREQAgayeeqlaqmQQKVLD 832
Cdd:PRK04863   311 EMARELAELNEAESDLEQDYQAasdHLnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEA----------DEQQEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  833 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLeRQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 912
Cdd:PRK04863   381 NEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQY-QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QmreeqakeieiLKQTLSSKEESISILHEEYETKFK-NQEKRMEKIKQKAKEM---QETKKKLLDQEAKLKKELEntvlE 988
Cdd:PRK04863   460 S-----------LEQKLSVAQAAHSQFEQAYQLVRKiAGEVSRSEAWDVARELlrrLREQRHLAEQLQQLRMRLS----E 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  989 LSQKEKQFNAQILEMAQANSagisdtVSRLEENQRQQIESLTGAHQRKLDDvieawekkLSQQAAELRDKHAEQMEEKEQ 1068
Cdd:PRK04863   525 LEQRLRQQQRAERLLAEFCK------RLGKNLDDEDELEQLQEELEARLES--------LSESVSEARERRMALRQQLEQ 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1069 gLGELRQKVRIVQSEKEELTKEVARLKEAV-----SGQDVaLAGLQGQLEQKSAVIVS---LSERESQLQSQVEKLEADL 1140
Cdd:PRK04863   591 -LQARIQRLAARAPAWLAAQDALARLREQSgeefeDSQDV-TEYMQQLLERERELTVErdeLAARKQALDEEIERLSQPG 668

                          490
                   ....*....|....
gi 1907199001 1141 GCSLSEKLSLQEEL 1154
Cdd:PRK04863   669 GSEDPRLNALAERF 682
COG5022 COG5022
Myosin heavy chain [General function prediction only];
815-1366 9.48e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 9.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  815 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQ----VQQLERQRSELEEKVRSLAQL--QDS 888
Cdd:COG5022    823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQsaqrVELAERQLQELKIDVKSISSLklVNL 902

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  889 QLKNSTVEKEQARQSLMEKENIILQ---------------------MREEQAKEIEIL--KQTLSSKEESISILHEEYET 945
Cdd:COG5022    903 ELESEIIELKKSLSSDLIENLEFKTeliarlkkllnnidleegpsiEYVKLPELNKLHevESKLKETSEEYEDLLKKSTI 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK--KELENTVLELSQKEKQFNAQILEMAQANSagISDTVSRLEENQR 1023
Cdd:COG5022    983 LVREGNKANSELKNFKKELAELSKQYGALQESTKqlKELPVEVAELQSASKIISSESTELSILKP--LQKLKGLLLLENN 1060

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1024 QQIESLTGAHQRKLDDVI-----------EAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVA 1092
Cdd:COG5022   1061 QLQARYKALKLRRENSLLddkqlyqlestENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVN 1140

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1093 RLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEEL-AELKLLADKS------Q 1165
Cdd:COG5022   1141 TLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLkNELIALFSKIfsgwprG 1220

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1166 LRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRC--ERTKALLEAKTNELVCTSRDKADAI 1243
Cdd:COG5022   1221 DKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsyKLEEEVLPATINSLLQYINVGLFNA 1300

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1244 LArlSQCQRHTATVGEAL----------LRRMGqVSELEAQLTQLTEEQRTLkssfQQVTNQLEEKEKQIKTMK----AD 1309
Cdd:COG5022   1301 LR--TKASSLRWKSATEVnynseelddwCREFE-ISDVDEELEELIQAVKVL----QLLKDDLNKLDELLDACYslnpAE 1373

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 1310 IEGLLTEKEALQQEGG--QQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEI 1366
Cdd:COG5022   1374 IQNLKSRYDPADKENNlpKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1055-1298 1.10e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1055 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKeavsgQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 1134
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1135 KLEADLgcslsEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQsckslhELSKKSLED--KSLNLKSLLEELAS 1212
Cdd:COG3206    237 EAEARL-----AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA------ELSARYTPNhpDVIALRAQIAALRA 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1213 QLDSRCERTKALLEAKTNELvctsRDKADAILARLSQcqrhtatvgeaLLRRMGQVSELEAQLTQLTEEQRTLKSSFQQV 1292
Cdd:COG3206    306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQ-----------LEARLAELPELEAELRRLEREVEVARELYESL 370


                   ....*.
gi 1907199001 1293 TNQLEE 1298
Cdd:COG3206    371 LQRLEE 376
46 PHA02562
endonuclease subunit; Provisional
 827-1066 1.14e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.85  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  827 QQKVLDLETEKSLLTKQVvemETHKKHVcEELDAQRAQ-VQQLERQRSELEEKVRSLAQLQDS---QLKNSTVEKEqarq 902
Cdd:PHA02562   180 NQQIQTLDMKIDHIQQQI---KTYNKNI-EEQRKKNGEnIARKQNKYDELVEEAKTIKAEIEEltdELLNLVMDIE---- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  903 slmEKENIILQMREEQAKeieilkqtLSSKEESISILHEEYET---------KFKNQEKRMEKIKQKAKEMQETKKKLLD 973
Cdd:PHA02562   252 ---DPSAALNKLNTAAAK--------IKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  974 QEAKLkKELENTVLELSQKEKQFNAQIlemaQANSAGISDTVSRLEENQRqQIESLTGAHQRKLDDVieaweKKLSQQAA 1053
Cdd:PHA02562   321 AIDEL-EEIMDEFNEQSKKLLELKNKI----STNKQSLITLVDKAKKVKA-AIEELQAEFVDNAEEL-----AKLQDELD 389

                          250
                   ....*....|...
gi 1907199001 1054 ELRDKHAEQMEEK 1066
Cdd:PHA02562   390 KIVKTKSELVKEK 402
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 687-932 1.21e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  687 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQeltvrraeKALKDELSRLGAL 766
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQEL--------AALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  767 LDERDEHLRERQARVQDLEAHLQKSAgelQQALAKLdLLHSEQSAAREQAGAYEEQLAQMQQKVLDLetekslLTKQVVE 846
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLG---RQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEE------LRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  847 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQdSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILK 926
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLL-ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*.
gi 1907199001  927 QTLSSK 932
Cdd:COG4942    241 ERTPAA 246
PRK01156 PRK01156
chromosome segregation protein; Provisional
 795-1382 1.24e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  795 LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSE 874
Cdd:PRK01156   178 LRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  875 LEEKVRSLAQLQDSQLKNSTVEKEqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILheeyetkfKNQEKRM 954
Cdd:PRK01156   258 IKTAESDLSMELEKNNYYKELEER-----HMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI--------DAEINKY 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  955 EKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANsagisdtvsRLEENQRQQIESLTGAHQ 1034
Cdd:PRK01156   325 HAIIKKLSVLQKDYNDYIKKKSR-YDDLNNQILELEGYEMDYNSYLKSIESLK---------KKIEEYSKNIERMSAFIS 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1035 RKLdDVIEAWEKKLSQQAAELRDKhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLkeavSGQDVA-LAGLQGQLE 1113
Cdd:PRK01156   395 EIL-KIQEIDPDAIKKELNEINVK----LQDISSKVSSLNQRIRALRENLDELSRNMEML----NGQSVCpVCGTTLGEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1114 QKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSLQEELAElkLLADKSQLRVSELTGQVQAAEKELQSckslHELSK 1193
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEKIREIEIEVK-DIDEKIVDLKKRKE--YLESEEINKSINEYNKIESARADLED----IKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1194 KSLEDKSLNLKSLLEELAS----QLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTAtvgEALLRRMGQVS 1269
Cdd:PRK01156   539 NELKDKHDKYEEIKNRYKSlkleDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ---EIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1270 ELEAQLTQLTEEQRTLKSSFqqvtNQLEEKEKQIKTMKADIEGL---LTEKEALQQEGGQQRQAASEKESCITQLKKELA 1346
Cdd:PRK01156   616 YIDKSIREIENEANNLNNKY----NEIQENKILIEKLRGKIDNYkkqIAEIDSIIPDLKEITSRINDIEDNLKKSRKALD 691

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1907199001 1347 ENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES 1382
Cdd:PRK01156   692 DAKANRARLESTIEILRTRINELSDRINDINETLES 727
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1441-2077 1.35e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1441 EWKKKAQSRLAQHQSTIKDLQAQLDV-----KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1515
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVleetqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1516 ALKTQTA--RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSS 1593
Cdd:TIGR00618  333 HVKQQSSieEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1594 LEAELGTVKKELEHVNSSvksrDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1673
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHA----KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1674 SAQLKEREKQVHSLEDKLKNlESSPHPEVPAVSRSMQSVAASPEQEAPDsqdcTHKACKERLCMLQRRLSEKEKLLRRLE 1753
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQRGEQ----TYAQLETSEEDVYHQLTSERKQRASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1754 QGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVL-IGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1832
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1833 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDgenkcvevLEDRPEENSQSHEIQSNVG 1912
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW--------KEMLAQCQTLLRELETHIE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1913 TVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDIlkrECEQEAEEKLKQEQEDLELKHTSTLKQLMR 1992
Cdd:TIGR00618  715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE---AHFNNNEEVTAALQTGAELSHLAAEIQFFN 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1993 EFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDARE--EEMTGKVTDL 2070
Cdd:TIGR00618  792 RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKI 871


                   ....*..
gi 1907199001 2071 QTQLEEL 2077
Cdd:TIGR00618  872 IQLSDKL 878
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1960-2042 1.35e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 44.05  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1960 LKRECEQEAEE--KLKQEQEDLELKhtstLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRK 2037
Cdd:PRK00409   528 LERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYAS 603


                   ....*
gi 1907199001 2038 IAEKE 2042
Cdd:PRK00409   604 VKAHE 608
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1914-2111 1.59e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1914 VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREH------QQELDILKRECE--QEAEEKLKQEQEDLE-LKHT 1984
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyaelQEELEELEEELEelEAELEELREELEKLEkLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1985 STLKQLMREFNTQLAQKEQELER------TVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDA 2058
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEEleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199001 2059 REEemtgkvtdLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLI 2111
Cdd:COG4717    208 LAE--------LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL 252
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 584-828 2.10e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  584 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 660
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  661 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 736
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  737 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 816
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907199001  817 GAyEEQLAQMQQ 828
Cdd:NF012221  1757 AA-ENKANQAQA 1767
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 755-1390 2.26e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  755 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLdllhSEQSAAREQAGAYEEQLAQMQQKVLDLE 834
Cdd:TIGR00618  198 LLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  835 TEKSLLTKQ--VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqlknstvekeqarqsLMEKENIIL 912
Cdd:TIGR00618  274 AQEAVLEETqeRINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKL------------------LMKRAAHVK 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  913 QMREEQakEIEILKQTLSSKEESISILHEEyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEntvlelsqK 992
Cdd:TIGR00618  336 QQSSIE--EQRRLLQTLHSQEIHIRDAHEV-ATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELD--------I 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  993 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE 1072
Cdd:TIGR00618  405 LQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1073 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLqGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslsekLSLQE 1152
Cdd:TIGR00618  485 ETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDI-DNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-------TSERK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1153 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNEL 1232
Cdd:TIGR00618  557 QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQ 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1233 VCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQrTLKSSFQQVTNQLEEKEKQIKTMKADIEG 1312
Cdd:TIGR00618  637 CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ-SEKEQLTYWKEMLAQCQTLLRELETHIEE 715

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1313 LLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKA 1390
Cdd:TIGR00618  716 YDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRL 793
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1899-2090 2.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1899 EENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-----EKLK 1973
Cdd:COG4942     38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralYRLG 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1974 QEQEDLELKHTSTLKQ------LMREFNTQLAQKEQELERTVQETIDKAQEVEAE------LLESHQEETQQLHRKIAEK 2041
Cdd:COG4942    118 RQPPLALLLSPEDFLDavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAEraeleaLLAELEEERAALEALKAER 197

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199001 2042 EDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 2090
Cdd:COG4942    198 QKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK11281 PRK11281
mechanosensitive channel MscK;
1929-2132 2.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 43.36  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1929 ERDKQKLSKEVARLQKELRalrrEHQQELDILKRECEQEAEEKL-KQEQEDLELKHTSTLKQL------MREFNTQLAQK 2001
Cdd:PRK11281    79 KEETEQLKQQLAQAPAKLR----QAQAELEALKDDNDEETRETLsTLSLRQLESRLAQTLDQLqnaqndLAEYNSQLVSL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2002 EQELERtVQETIDKA----QEVEAELLESHQEET-------QQLHRKIA--EKEDDLRRT----ARRYEEILDAREEEMT 2064
Cdd:PRK11281   155 QTQPER-AQAALYANsqrlQQIRNLLKGGKVGGKalrpsqrVLLQAEQAllNAQNDLQRKslegNTQLQDLLQKQRDYLT 233

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 2065 GKVTDLQTQLEELQKK-YQQRLEQEESTKDsvtilelQTQLAQKTTLISDSKLKEQELrEQVHNLEDRL 2132
Cdd:PRK11281   234 ARIQRLEHQLQLLQEAiNSKRLTLSEKTVQ-------EAQSQDEAARIQANPLVAQEL-EINLQLSQRL 294
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 308-1232 2.42e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  308 LSEKEALQEQLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQ------DKGMVITETKRQMLETLELKEDEIAQ 381
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEmrarlaARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  382 LRSHIKQMTTQGEELREQKEKSERAALYEQdwafeeLEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL-RLQHE 460
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAARQKLQ------LEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIsEFTSN 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  461 LSRVRQEAASMAK-KNSEEQVAA--LQKLHAEELASKEQE-LSRRLEARERELQEQmrIALEKSRSEYLKLTQEKEQQES 536
Cdd:pfam01576  168 LAEEEEKAKSLSKlKNKHEAMISdlEERLKKEEKGRQELEkAKRKLEGESTDLQEQ--IAELQAQIAELRAQLAKKEEEL 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  537 LALEELELQKKAILTESENKLQELgqeaeayRTRILELETSLEKSLQ---ESKTQSEHLAVHLEAEKNKHNKELTALAEQ 613
Cdd:pfam01576  246 QAALARLEEETAQKNNALKKIREL-------EAQISELQEDLESERAarnKAEKQRRDLGEELEALKTELEDTLDTTAAQ 318

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  614 HrtEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkeKESLFQAHIQDMNektlekLDKKQMELESVSS 693
Cdd:pfam01576  319 Q--ELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEEL---TEQLEQAKRNKAN------LEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  694 ELSEALRArdqlaeeLSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRraekaLKDELSRLGALLDERDEH 773
Cdd:pfam01576  388 ELQAELRT-------LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK-----LQSELESVSSLLNEAEGK 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  774 LRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEM------ 847
Cdd:pfam01576  456 NIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMkkklee 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  848 --------ETHKKHVCEELDAQR-------AQVQQLERQRSELEEKVRSLAQLQDSQLKN-STVEKEQAR--QSLMEKEN 909
Cdd:pfam01576  536 dagtlealEEGKKRLQRELEALTqqleekaAAYDKLEKTKNRLQQELDDLLVDLDHQRQLvSNLEKKQKKfdQMLAEEKA 615

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  910 IILQMREE------QAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEK-------IKQKAKEMQETKKKLLDQEA 976
Cdd:pfam01576  616 ISARYAEErdraeaEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDlvsskddVGKNVHELERSKRALEQQVE 695

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  977 KLKKELENTVLELSQKEkqfnaqilemaqansagisDTVSRLEENqrqqIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 1056
Cdd:pfam01576  696 EMKTQLEELEDELQATE-------------------DAKLRLEVN----MQALKAQFERDLQARDEQGEEKRRQLVKQVR 752

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1057 DKHAEQMEEKEQGLGEL--RQKVRIVQSEKEELTKEVARLKEAVSGQdvaLAGLQGQLEQKSAVIVSLSERESQLQSQVE 1134
Cdd:pfam01576  753 ELEAELEDERKQRAQAVaaKKKLELDLKELEAQIDAANKGREEAVKQ---LKKLQAQMKDLQRELEEARASRDEILAQSK 829

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1135 KLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAekelQSCKSLHELSKKSLEDKSLNLKSLLEELASQ- 1213
Cdd:pfam01576  830 ESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASG----ASGKSALQDEKRRLEARIAQLEEELEEEQSNt 905

                          970       980
                   ....*....|....*....|.
gi 1907199001 1214 --LDSRCERTKALLEAKTNEL 1232
Cdd:pfam01576  906 elLNDRLRKSTLQVEQLTTEL 926
PRK12704 PRK12704
phosphodiesterase; Provisional
 483-663 2.53e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  483 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQ 562
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---------------LRERRNELQKLEK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  563 eaeayrtRILELETSLEKSLQESKTQSEhlavHLEAEKNKHNKELTALAEQhRTEVEGLQQQQDslwtERLQSLSQ--QH 640
Cdd:PRK12704    90 -------RLLQKEENLDRKLELLEKREE----ELEKKEKELEQKQQELEKK-EEELEELIEEQL----QELERISGltAE 153

                          170       180
                   ....*....|....*....|....*.
gi 1907199001  641 QA---AVEELREKYQQEKDALLKEKE 663
Cdd:PRK12704   154 EAkeiLLEKVEEEARHEAAVLIKEIE 179
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1836-2149 2.56e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.19  E-value: 2.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1836 QEKELTCQALEQRVKELESDLVRERgahrlEVEKLTLKYEKSQSSQQEMDGENKCVEvLEDRPEENSQ--SHEIQSNVGT 1913
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQA-----EMDRQAAIYAEQERMAMERERELERIR-QEERKRELERirQEEIAMEISR 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1914 VDGLRSDLESKLTGAERDKQKLskEVARLQKelrALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMRE 1993
Cdd:pfam17380  377 MRELERLQMERQQKNERVRQEL--EAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1994 FNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEildaREEEMtgkvtdLQTQ 2073
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE----RKRKL------LEKE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2074 LEELQK---KYQQRLEQEESTKDSVTILE---LQTQLAQKTTLIS--DSKLKEQELREQVHNLEDRLKRYEKNACAATVG 2145
Cdd:pfam17380  522 MEERQKaiyEEERRREAEEERRKQQEMEErrrIQEQMRKATEERSrlEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   ....
gi 1907199001 2146 TPYK 2149
Cdd:pfam17380  602 PIYR 605
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 576-830 2.99e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 42.63  E-value: 2.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  576 TSLEKSLQESKTQSEHLAVHLEAEKNK-----------------HNKELTA----LAEQHRTEVEGLQQQQDSLWTERLQ 634
Cdd:pfam07902   74 TGLFKSLEEMLSQLKELNLELTDTKNSnlwskiklnnngmlreyHNDTIKTeiveSAEGIATRISEDTDKKLALINETIS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  635 SLSQQHQAAVEELREKYQQEKDAL---LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrARDQLAEELSV 711
Cdd:pfam07902  154 GIRREYQDADRQLSSSYQAGIEGLkatMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAKITTTSSG--TTEAYESKLDD 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  712 LRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkdeLSRLGALLDerdehlrERQARVQDLEahlqKS 791
Cdd:pfam07902  232 LRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGA----VSRVQQDLD-------SYQRRLQDAE----KN 296

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907199001  792 AGELQQALAKLdllhseQSAAREQAGAYEEQLAQMQ----QKV 830
Cdd:pfam07902  297 YSSLTQTVKGL------QSTVSDPNSKLESRITQLAglieQKV 333
mukB PRK04863
chromosome partition protein MukB;
451-1195 3.08e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  451 EEERLRLQHELSRVRQEAASmakknSEEQVAALQKLHaEELASKEQELSRRLEARERELQ----------EQMRI--ALE 518
Cdd:PRK04863   278 ANERRVHLEEALELRRELYT-----SRRQLAAEQYRL-VEMARELAELNEAESDLEQDYQaasdhlnlvqTALRQqeKIE 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  519 KSRSEYLKLTQEKEQQESLALEELELQkkailTESENKLQELGQEAEAYRTRILELETSLEksLQESKTQSEHLAVHLEA 598
Cdd:PRK04863   352 RYQADLEELEERLEEQNEVVEEADEQQ-----EENEARAEAAEEEVDELKSQLADYQQALD--VQQTRAIQYQQAVQALE 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  599 EKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQ---HQAAVEELREKYQ---------QEKDALLKEKESLF 666
Cdd:PRK04863   425 RAKQLCGLPDLTADNAEDWLEEFQAKEQEA-TEELLSLEQKlsvAQAAHSQFEQAYQlvrkiagevSRSEAWDVARELLR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  667 QAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMkQALEAELEEQRRHHQREVGSISEQQE 746
Cdd:PRK04863   504 RLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEL-EQLQEELEARLESLSESVSEARERRM 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  747 lTVRRAEKALKDELSRLGAL------LDERDEHLRE----RQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 816
Cdd:PRK04863   583 -ALRQQLEQLQARIQRLAARapawlaAQDALARLREqsgeEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEI 661

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  817 -------GAYEEQLAQMQQK---------------------------------VLDLETEKSLLTKQ------------- 843
Cdd:PRK04863   662 erlsqpgGSEDPRLNALAERfggvllseiyddvsledapyfsalygparhaivVPDLSDAAEQLAGLedcpedlyliegd 741

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  844 -------VVEMETHKKHVCEEL-DAQ--------------RAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEK--- 897
Cdd:PRK04863   742 pdsfddsVFSVEELEKAVVVKIaDRQwrysrfpevplfgrAAREKRIEQLRAEREELAERYATLSfDVQKLQRLHQAfsr 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  898 ------------------EQARQSLMEKENIILQMRE------EQAKEIEILKQTLSSKEESISILHEEyetkfkNQEKR 953
Cdd:PRK04863   822 figshlavafeadpeaelRQLNRRRVELERALADHESqeqqqrSQLEQAKEGLSALNRLLPRLNLLADE------TLADR 895

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  954 MEKIKQKAKEMQETkKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAH 1033
Cdd:PRK04863   896 VEEIREQLDEAEEA-KRFVQQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQT---------QRDAKQQAFALTEVV 965

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1034 QRKLDDVIEAWEKKLSqQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLE 1113
Cdd:PRK04863   966 QRRAHFSYEDAAEMLA-KNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQ 1044

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1114 QKSAVIVslSERESQLQSQVEKLEADLGCSLSEKLSLQEELAelklladKSQLRVSELTGQVQAAEKELQSCKSLHELSK 1193
Cdd:PRK04863  1045 DLGVPAD--SGAEERARARRDELHARLSANRSRRNQLEKQLT-------FCEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115


                   ..
gi 1907199001 1194 KS 1195
Cdd:PRK04863  1116 AG 1117
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
939-1396 3.16e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 3.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  939 LHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAklkkELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 1018
Cdd:COG4913    240 AHEALEDA-REQIELLEPIRELAERYAAARERLAELEY----LRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1019 EENQRQQIESLTGAHQRKLD---DVIEAWEKKLSQQAAELRDK--HAEQMEEKEQGLG--------ELRQKVRIVQSEKE 1085
Cdd:COG4913    315 EARLDALREELDELEAQIRGnggDRLEQLEREIERLERELEERerRRARLEALLAALGlplpasaeEFAALRAEAAALLE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1086 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslSEKLSLQEelAELKLLADKSQ 1165
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGLDE--AELPFVGELIE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1166 LRVSELTGQvQAAEKELQSCK------------------SLH----------ELSKKSLEDKSLNLKSLLEELASQLDSR 1217
Cdd:COG4913    469 VRPEEERWR-GAIERVLGGFAltllvppehyaaalrwvnRLHlrgrlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPF 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1218 CERTKALLEAKTNELVCTS----RDKADAILArlsQCQ-RHTATVGEALLRRMG------------QVSELEAQLTQLTE 1280
Cdd:COG4913    548 RAWLEAELGRRFDYVCVDSpeelRRHPRAITR---AGQvKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1281 EQRTLKSSFQQVTNQLEEKEKQIKTMKA---------DIEGLLTEKEALQqeggQQRQAASEKESCITQLKKELAENINA 1351
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE----AELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1907199001 1352 VTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISAL 1396
Cdd:COG4913    701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1552-1695 3.39e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.54  E-value: 3.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1552 RDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELgtvkkelehvnssvKSRDGELKALEDKLElesa 1631
Cdd:COG2433    390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL--------------EEKDERIERLERELS---- 451

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199001 1632 akvELKRKAEQKIaairkqllsqmeeKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1695
Cdd:COG2433    452 ---EARSEERREI-------------RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1061-1680 3.55e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 3.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1061 EQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA-- 1138
Cdd:PRK03918   158 DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElk 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1139 -DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE-----DKSLNLKSLLEELAS 1212
Cdd:PRK03918   238 eEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKlsefyEEYLDELREIEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1213 QLDSRCERTKALLE--AKTNELVCTSRDKADAILARLSQCQRHTATVGEAlLRRMGQVSELEAQLTQLTEEqrtlkssfq 1290
Cdd:PRK03918   318 RLEEEINGIEERIKelEEKEERLEELKKKLKELEKRLEELEERHELYEEA-KAKKEELERLKKRLTGLTPE--------- 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1291 QVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKES-------CITQLKKELAENINAVtlLREELSEKK 1363
Cdd:PRK03918   388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvCGRELTEEHRKELLEE--YTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1364 SEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEkmsaLEQVDHWSNKFsewk 1443
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEE----YEKLKEKLIKL---- 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1444 KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQIC-LLKEDLDRQNKKFECLKGEMEvRKSKMEKKECDLETALKTQTA 1522
Cdd:PRK03918   538 KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAeLLKELEELGFESVEELEERLK-ELEPFYNEYLELKDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1523 RVVELEDCVTQRKKEVESLNETLKNYNQQRdtehsglvqrlQHLEELGEE-KDNKVREAEETVLRLREHVSSLEAELGTV 1601
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELR-----------KELEELEKKySEEEYEELREEYLELSRELAGLRAELEEL 685

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199001 1602 KKELEHVNSSVKSRDGELKALEDKLElesaaKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKER 1680
Cdd:PRK03918   686 EKRREEIKKTLEKLKEELEEREKAKK-----ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTEG 759
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1081-1305 3.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1081 QSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLL 1160
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1161 AdKSQLRVSELTGQvQAAEKELQSCKSLHELSKKSLEDKSLN--LKSLLEELASQLDsRCERTKALLEAKTNELvctsRD 1238
Cdd:COG4942    106 L-AELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLApaRREQAEELRADLA-ELAALRAELEAERAEL----EA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199001 1239 KADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1305
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 822-1002 3.61e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  822 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQA 900
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVeARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  901 RQSLMekeniilqmreeqaKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 980
Cdd:COG1579     91 YEALQ--------------KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA 156

                          170       180
                   ....*....|....*....|..
gi 1907199001  981 ELENTVLELSQKEKQFNAQILE 1002
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1933-2125 3.79e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 3.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1933 QKLSKEVARLQKELRALRREH------QQELDILKRECEQEAE-EKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 2005
Cdd:COG3206    185 PELRKELEEAEAALEEFRQKNglvdlsEEAKLLLQQLSELESQlAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2006 ERTVQETIDKAQEVEAELLESHQEET---QQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQ 2082
Cdd:COG3206    265 IQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907199001 2083 QRLEQEestkdsVTILELQTQLAQKTTLISD--SKLKEQELREQV 2125
Cdd:COG3206    345 ELPELE------AELRRLEREVEVARELYESllQRLEEARLAEAL 383
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 952-1567 4.12e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 42.43  E-value: 4.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  952 KRMEKIKQKAKEMQETKKKLLDQEAKLKKE-LENTVLELSQKEKQFNAQILEMAQAnsaGISDTVSRLEENQRQQIESLT 1030
Cdd:pfam07111   70 RQLQELRRLEEEVRLLRETSLQQKMRLEAQaMELDALAVAEKAGQAEAEGLRAALA---GAEMVRKNLEEGSQRELEEIQ 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1031 GAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQkVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQG 1110
Cdd:pfam07111  147 RLHQEQLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQ-LAEAQKEAELLRKQLSKTQEELEAQVTLVESLRK 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1111 QLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSckslhe 1190
Cdd:pfam07111  226 YVGEQVPPEVHSQTWELERQELLDTMQ-----------HLQEDRADLQATVELLQVRVQSLTHMLALQEEELTR------ 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1191 lskksledKSLNLKSLLEELASqldsrcertkalleaKTNELVCTSRDKADAILARL-SQCQRHTATVGEAllrrMGQVS 1269
Cdd:pfam07111  289 --------KIQPSDSLEPEFPK---------------KCRSLLNRWREKVFALMVQLkAQDLEHRDSVKQL----RGQVA 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1270 ELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ-------AASEKESCITQLK 1342
Cdd:pfam07111  342 ELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEEqlkfvvnAMSSTQIWLETTM 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1343 KELAENINAVTLLREELSEKKSEIAS----LSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKV 1418
Cdd:pfam07111  422 TRVEQAVARIPSLSNRLSYAVRKVHTikglMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSA 501

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1419 DALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKF----EC 1494
Cdd:pfam07111  502 HLIQQEVGRAREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYgqalQE 581

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199001 1495 LKGEMEVR-KSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLE 1567
Cdd:pfam07111  582 KVAEVETRlREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQELE 655
PLN02939 PLN02939
transferase, transferring glycosyl groups
 886-1209 4.21e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.58  E-value: 4.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  886 QDSQLKN----STVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH-EEYETKFKNQEKRMEKIKQK 960
Cdd:PLN02939    71 ENGQLENtslrTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLVGMIQNAEKNILLLNQA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  961 AKEMQETKKKLLDQEAKLKKELENTVLELSQK--------EKQFNAQIL---------EMAQANSAGISDTVSRLEENQR 1023
Cdd:PLN02939   151 RLQALEDLEKILTEKEALQGKINILEMRLSETdariklaaQEKIHVEILeeqleklrnELLIRGATEGLCVHSLSKELDV 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1024 QQIESLTgahqrkLDDVIEAWEKKLS--QQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEL-TKEVARLKEAVSG 1100
Cdd:PLN02939   231 LKEENML------LKDDIQFLKAELIevAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLsPLQYDCWWEKVEN 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1101 QDVALAGLQGQLEQKSAVIvslsERESQLQSQVEKLEADLGCSLSEKLSLQeelaelklLADKSQLRVSELTGQVQAAEK 1180
Cdd:PLN02939   305 LQDLLDRATNQVEKAALVL----DQNQDLRDKVDKLEASLKEANVSKFSSY--------KVELLQQKLKLLEERLQASDH 372

                          330       340
                   ....*....|....*....|....*....
gi 1907199001 1181 ELQSCKSLHELSKKSLEDkslNLKSLLEE 1209
Cdd:PLN02939   373 EIHSYIQLYQESIKEFQD---TLSKLKEE 398
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1466-2135 4.42e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 4.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1466 VKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK---KECDLETALKTQTARVVELEDCVTQRKKEVESLN 1542
Cdd:PRK03918   141 LESDESREKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKfikRTENIEELIKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1543 ETLKNYnqqrdtehSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKAL 1622
Cdd:PRK03918   221 EELEKL--------EKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKEL 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1623 EDKlELESAAKVELKRKAEQKIAAIRKQL--LSQMEEKTQRYAKDTEN---RLSELSAQLKEREKQVHSLEDKLKNLEss 1697
Cdd:PRK03918   289 KEK-AEEYIKLSEFYEEYLDELREIEKRLsrLEEEINGIEERIKELEEkeeRLEELKKKLKELEKRLEELEERHELYE-- 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1698 phpEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDC 1777
Cdd:PRK03918   366 ---EAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELK----KAIEELKKAKGKC 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1778 -TRARQLEDHVLIGCLPEELEEkmkcslivsqpmgeetgnntgvkqnwasvVDSVQKTLQEKELTCQALEQRVKELESDL 1856
Cdd:PRK03918   439 pVCGRELTEEHRKELLEEYTAE-----------------------------LKRIEKELKEIEEKERKLRKELRELEKVL 489

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1857 VRERgahrlEVEKLTLKYEKSQSSQQEMDGENkcvevLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLtgaeRDKQKLS 1936
Cdd:PRK03918   490 KKES-----ELIKLKELAEQLKELEEKLKKYN-----LEELEKKAEEYEKLKEKLIKLKGEIKSLKKEL----EKLEELK 555

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1937 KEVARLQKELRALRREHQQELDILKR---ECEQEAEEKLKQeqedlelkhtstLKQLMREFNTqLAQKEQELERtvqeti 2013
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEElgfESVEELEERLKE------------LEPFYNEYLE-LKDAEKELER------ 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2014 dkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKD 2093
Cdd:PRK03918   617 ------EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRRE 690

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907199001 2094 SV--TILELQTQLAQKTTLISDSKLKE------QELREQVHNLEDRLKRY 2135
Cdd:PRK03918   691 EIkkTLEKLKEELEEREKAKKELEKLEkalervEELREKVKKYKALLKER 740
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
680-805 4.82e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.57  E-value: 4.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  680 KLDKKQMELESVSSELsEALRARDQLAEELSVLRGDADKMKQALE-AELEEQRRHHQREVGSISEQQELTVRRAEKALKD 758
Cdd:COG1566     84 ALAQAEAQLAAAEAQL-ARLEAELGAEAEIAAAEAQLAAAQAQLDlAQRELERYQALYKKGAVSQQELDEARAALDAAQA 162

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199001  759 ELSRLGALLDERDEHLRErQARVQDLEAHLQKSAGELQQALAKLDLL 805
Cdd:COG1566    163 QLEAAQAQLAQAQAGLRE-EEELAAAQAQVAQAEAALAQAELNLART 208
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 907-1129 5.95e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  907 KENIIlqmreEQAKEIeilkqtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTV 986
Cdd:PRK00409   500 PENII-----EEAKKL------IGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLL 568

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  987 LELSQKEKqfnaQILEMAQANSAGIsdtVSRLEENQRQQIESLtgahqrKLDDVIEAweKKLSQQAAELRDKHAEQMEEK 1066
Cdd:PRK00409   569 EEAEKEAQ----QAIKEAKKEADEI---IKELRQLQKGGYASV------KAHELIEA--RKRLNKANEKKEKKKKKQKEK 633

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001 1067 EQGL--GE------LRQKVRIVQ-SEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQL 1129
Cdd:PRK00409   634 QEELkvGDevkylsLGQKGEVLSiPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSL 705
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 312-698 5.95e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  312 EALQEQL---DERLQELEKMKELHMA--EKTKLITQLRDAKNL-------------IEQLEQDkgmvITETKRQMLET-- 371
Cdd:PRK10929    48 EALQSALnwlEERKGSLERAKQYQQVidNFPKLSAELRQQLNNerdeprsvppnmsTDALEQE----ILQVSSQLLEKsr 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  372 -LELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAaLYEQDWAFEELEKALSTAQKTEDAQRRMKMEMDE--QMKAVER 448
Cdd:PRK10929   124 qAQQEQDRAREISDSLSQLPQQQTEARRQLNEIERR-LQTLGTPNTPLAQAQLTALQAESAALKALVDELElaQLSANNR 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  449 aseeerlrlqHELSRVRQEaasMAKKNSEEQVAALQKLHAEELASKEQELSRRLEAREReLQEQMRiALEKSRSEYLK-- 526
Cdd:PRK10929   203 ----------QELARLRSE---LAKKRSQQLDAYLQALRNQLNSQRQREAERALESTEL-LAEQSG-DLPKSIVAQFKin 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  527 --LTQEKEQQESLALEELELQKKAIltesenklqelgqeaeayrTRILELETSLeKSLQEsktQSEHLAVHleaeknkhn 604
Cdd:PRK10929   268 reLSQALNQQAQRMDLIASQQRQAA-------------------SQTLQVRQAL-NTLRE---QSQWLGVS--------- 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  605 kelTALAEQHRTEVEGL-----QQQQDS----LWTERL---------QSLSQQHQAAVEELREKYQQEKDALLKEKESLF 666
Cdd:PRK10929   316 ---NALGEALRAQVARLpempkPQQLDTemaqLRVQRLryedllnkqPQLRQIRQADGQPLTAEQNRILDAQLRTQRELL 392

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1907199001  667 QAHIQDMNEKTLE--KLDKKQMELESVSSELSEA 698
Cdd:PRK10929   393 NSLLSGGDTLILEltKLKVANSQLEDALKEVNEA 426
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1915-2025 5.99e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 5.99e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  1915 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 1987
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907199001  1988 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 2025
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1596-1952 6.04e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1596 AELGTVKKELEHVNSSVKSRDGELKALEDKLE--LESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1673
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREkaERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1674 SAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDcTHKACKERLCMLQRRLSEKEKLLRRLE 1753
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLER-SIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1754 qgegearpsqpeAQHRALSGKLDCTRARQLEdhvligcLPEELEEKmkcslivsqpmgeetgnntgvkqnwASVVDSVQK 1833
Cdd:TIGR02169  336 ------------AEIEELEREIEEERKRRDK-------LTEEYAEL-------------------------KEELEDLRA 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1834 TLQEKELTCQALEQRVKELE---SDLVRERGAHRLEVEKLtlKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSN 1910
Cdd:TIGR02169  372 ELEEVDKEFAETRDELKDYReklEKLKREINELKRELDRL--QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907199001 1911 VGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRRE 1952
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRE 491
PRK01156 PRK01156
chromosome segregation protein; Provisional
 554-1096 6.42e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 6.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  554 ENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSE----------------HLAVHLEAEKNKHNKELTALaeQHRTE 617
Cdd:PRK01156   189 EEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIeynnamddynnlksalNELSSLEDMKNRYESEIKTA--ESDLS 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  618 VEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAhiqDMNEKTLEKLDKKQMELESVSSELSE 697
Cdd:PRK01156   267 MELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI---DAEINKYHAIIKKLSVLQKDYNDYIK 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  698 ALRARDQLAEELSVLRGDADKMKQALEA--ELEEQRRHHQREVGSISEQQELTVRRAE---KALKDELSRLGALLDERDE 772
Cdd:PRK01156   344 KKSRYDDLNNQILELEGYEMDYNSYLKSieSLKKKIEEYSKNIERMSAFISEILKIQEidpDAIKKELNEINVKLQDISS 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  773 HLRERQARVQDLEAHLQksagELQQALAKLD--------LLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV 844
Cdd:PRK01156   424 KVSSLNQRIRALRENLD----ELSRNMEMLNgqsvcpvcGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKI 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  845 VEMETHKKHVC-EELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKnstvekeqarqslmeKENIILQMReeqAKEIE 923
Cdd:PRK01156   500 VDLKKRKEYLEsEEINKSINEYNKIESARADLEDIKIKINELKDKHDK---------------YEEIKNRYK---SLKLE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  924 ILKQTLSSKEESISILHE-EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNaqile 1002
Cdd:PRK01156   562 DLDSKRTSWLNALAVISLiDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYN----- 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1003 MAQANSAGIsDTVSRLEENQRQQIESLtgahqrkldDVIEAWEKKLSQQAAELRD---KHAEQMEEKEQGLGELRQKVRI 1079
Cdd:PRK01156   637 EIQENKILI-EKLRGKIDNYKKQIAEI---------DSIIPDLKEITSRINDIEDnlkKSRKALDDAKANRARLESTIEI 706

                          570
                   ....*....|....*..
gi 1907199001 1080 VQSEKEELTKEVARLKE 1096
Cdd:PRK01156   707 LRTRINELSDRINDINE 723
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 132-534 6.48e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.64  E-value: 6.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  132 REQLLQRLRRMERSLSSY-RGKYSELVTAFQTLQREKKKLQGILSQ--SQDKSLRRISELREELQMDQQAKKHLQDEFDA 208
Cdd:pfam15921  424 RNMEVQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTA 503

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  209 CLEEKDQYISVLQTQVSLLKQRLQNGPMNVDAPKPlpPGELQAEVHGDTEKMEGVGEPVGggtsaKTLEMLQQRVkrqEN 288
Cdd:pfam15921  504 SLQEKERAIEATNAEITKLRSRVDLKLQELQHLKN--EGDHLRNVQTECEALKLQMAEKD-----KVIEILRQQI---EN 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  289 LLQrckeTIGSHKEQCALLLSEKEALQEQLDERLQELEKMKELhmaeKTKLITQLRDAKNLIEQLEQDKGMVITETKRQM 368
Cdd:pfam15921  574 MTQ----LVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKIL----KDKKDAKIRELEARVSDLELEKVKLVNAGSERL 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  369 LETLELKED------EIAQLRSHIKQMTTQGEELR-------EQKEKSERAALYEQDWAFEELEKALSTAQKTEDAQ-RR 434
Cdd:pfam15921  646 RAVKDIKQErdqllnEVKTSRNELNSLSEDYEVLKrnfrnksEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDgHA 725

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  435 MKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKlHAEELASKEQELSRRLE---ARERELQE 511
Cdd:pfam15921  726 MKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQ-ELSTVATEKNKMAGELEvlrSQERRLKE 804

                          410       420
                   ....*....|....*....|....*....
gi 1907199001  512 Q---MRIALEKSRSEYLK---LTQEKEQQ 534
Cdd:pfam15921  805 KvanMEVALDKASLQFAEcqdIIQRQEQE 833
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 868-1096 8.16e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 8.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  868 LERQRSELEEKVRSL--AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYET 945
Cdd:PRK05771    14 LKSYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  946 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKeLENTVLELsqkekqfnaqILEMAQANSAGISDTVSRLEENQRQQ 1025
Cdd:PRK05771    94 ELEKIEKEIKELEEEISELENEIKELEQEIERLEP-WGNFDLDL----------SLLLGFKYVSVFVGTVPEDKLEELKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1026 IESLTGA---HQRKLDDVIEAW-EKKLSQQAAELRDKH-AEQMEEKEQG-----LGELRQKVRIVQSEKEELTKEVARLK 1095
Cdd:PRK05771   163 ESDVENVeyiSTDKGYVYVVVVvLKELSDEVEEELKKLgFERLELEEEGtpselIREIKEELEEIEKERESLLEELKELA 242


                   .
gi 1907199001 1096 E 1096
Cdd:PRK05771   243 K 243
PRK11281 PRK11281
mechanosensitive channel MscK;
967-1385 8.25e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.44  E-value: 8.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  967 TKKKLLDQEAKL-KKELENTVLELSQKEKQfnaqilemaqansagisdtvsrleenqRQQIESLtgahqrklddvieawE 1045
Cdd:PRK11281    49 NKQKLLEAEDKLvQQDLEQTLALLDKIDRQ---------------------------KEETEQL---------------K 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1046 KKLSQQAAELRDKHAEQMEEKEQGLGELRQK-----VRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIV 1120
Cdd:PRK11281    87 QQLAQAPAKLRQAQAELEALKDDNDEETRETlstlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1121 SLSERESQLQSQVEKLEAD-LGCSLSEKLSLQEELAEL--------KLLADKSQL------RVSELTGQVQAAEKELQ-- 1183
Cdd:PRK11281   167 ANSQRLQQIRNLLKGGKVGgKALRPSQRVLLQAEQALLnaqndlqrKSLEGNTQLqdllqkQRDYLTARIQRLEHQLQll 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1184 ----SCKSLHELSKKSLEDKSLNLKSLLEE---LASQLDSRCERTKALLEA--KTNELvctSRD--KADAILARLSQCQR 1252
Cdd:PRK11281   247 qeaiNSKRLTLSEKTVQEAQSQDEAARIQAnplVAQELEINLQLSQRLLKAteKLNTL---TQQnlRVKNWLDRLTQSER 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1253 HtatvgeallrrmgqvseLEAQLTQLteeQRTLKSS---FQQvtNQLEEKEKQIKTMKADIEGLLTEkealQQEGGQQRQ 1329
Cdd:PRK11281   324 N-----------------IKEQISVL---KGSLLLSrilYQQ--QQALPSADLIEGLADRIADLRLE----QFEINQQRD 377

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199001 1330 AASEKESCITQLKKELAENINAVTL--LREELSEKKSEIASLSKQlsdLGAQLESSIS 1385
Cdd:PRK11281   378 ALFQPDAYIDKLEAGHKSEVTDEVRdaLLQLLDERRELLDQLNKQ---LNNQLNLAIN 432
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
438-886 8.25e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 8.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  438 EMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQmrIAL 517
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL--LQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  518 EKSRSEYLKLTQEKEQqeSLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE--------------KSLQ 583
Cdd:COG4717    128 LPLYQELEALEAELAE--LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlateeelqdlaeelEELQ 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  584 ESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEgLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKE 663
Cdd:COG4717    206 QRLAELEEELEEAQEELEELEEELEQLENELEAAAL-EERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  664 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrardQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISE 743
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEE-----ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  744 QQELTVRRAEKALKDELSRLGA-------LLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL--LHSEQSAARE 814
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVedeeelrAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELEELEE 439

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199001  815 QAGAYEEQLAQMQQKVLDLETEKSLLTKQvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQ 886
Cdd:COG4717    440 ELEELEEELEELREELAELEAELEQLEED------------GELAELLQELEELKAELRELAEEWAALKLAL 499
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 131-454 8.83e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.21  E-value: 8.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  131 SREQLLQRLRRMERSLSSYRGKYSELVTAFQTLQREkkklQGILSQSQDKSLRRISELREELQMDQQ---AKKHLQDEFD 207
Cdd:TIGR02169  689 ELSSLQSELRRIENRLDELSQELSDASRKIGEIEKE----IEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELE 764

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  208 ACLEEKDQYISVLQTQVSLLKQRLQNGPMnvdaPKPLPPGELQAEVHGDTEKMEGVGEPVGGGTSAKtLEMLQQRVKRQE 287
Cdd:TIGR02169  765 ARIEELEEDLHKLEEALNDLEARLSHSRI----PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE-KEYLEKEIQELQ 839

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  288 NLLQRCKETIGSHKEQCALLLSEKEALQE----------QLDERLQELEKMKELHMAEKTKLITQLRDAKNLIEQLEQDK 357
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEeleeleaalrDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001  358 GmvitetkrQMLETLELKEDEIAQLRSHIKQMTTQ-GEELREQKEKSERAALYEQDWAFEELEkaLSTAQKTEDAQRRMK 436
Cdd:TIGR02169  920 S--------ELKAKLEALEEELSEIEDPKGEDEEIpEEELSLEDVQAELQRVEEEIRALEPVN--MLAIQEYEEVLKRLD 989

                          330
                   ....*....|....*....
gi 1907199001  437 MEMDEQMK-AVERASEEER 454
Cdd:TIGR02169  990 ELKEKRAKlEEERKAILER 1008
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1267-1382 8.92e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199001 1267 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKAD--IEGLLTEKEALQQEGGQQRQAASEKESCITQLKKE 1344
Cdd:COG3206    220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1907199001 1345 LAENINAV-TLLREELSEKKSEIASLSKQLSDLGAQLES 1382
Cdd:COG3206    300 IAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQ 338
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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