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Conserved domains on  [gi|1907199025|ref|XP_036011010|]
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golgin subfamily A member 4 isoform X26 [Mus musculus]

Protein Classification

GRIP and coiled-coil domain-containing protein( domain architecture ID 13380436)

GRIP and coiled-coil domain-containing protein similar to Mus musculus GRIP and coiled-coil domain-containing protein 1 that is probably involved in maintaining Golgi structure

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 155-736 2.93e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.93e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  155 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 226
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  227 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 306
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  307 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 386
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  387 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 463
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  464 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 541
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  542 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 621
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  622 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 701
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199025  702 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 736
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 474-1053 1.03e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.46  E-value: 1.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  474 RDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRAEKALKDELSRLGALLDERDEHLRERQA 551
Cdd:COG1196    195 LGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  552 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELD 631
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  632 AQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISIL 711
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  712 HEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 790
Cdd:COG1196    434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  791 EENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARL 866
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  867 KEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQ 946
Cdd:COG1196    594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  947 VQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELV--CTSRDKADAILARLSQCQR 1024
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAleEQLEAEREELLEELLEEEE 746

                          570       580
                   ....*....|....*....|....*....
gi 1907199025 1025 HTATVGEALLRRMGQVSELEAQLTQLTEE 1053
Cdd:COG1196    747 LLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1467 1.54e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  773 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 847
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  848 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 927
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  928 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1007
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1008 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1083
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1084 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1153
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1154 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1209
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1210 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1273
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1274 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1340
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1341 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1420
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199025 1421 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1243-1911 1.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1243 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1322
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1323 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1402
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1403 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1482
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1483 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1559
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1560 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1612
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1613 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1675
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1676 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1755
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1756 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 1835
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1836 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 1910
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199025 1911 A 1911
Cdd:TIGR02168  910 R 910
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1936-1979 5.46e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.46e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199025  1936 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 1979
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 155-736 2.93e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.93e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  155 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 226
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  227 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 306
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  307 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 386
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  387 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 463
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  464 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 541
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  542 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 621
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  622 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 701
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199025  702 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 736
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 474-1053 1.03e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.46  E-value: 1.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  474 RDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRAEKALKDELSRLGALLDERDEHLRERQA 551
Cdd:COG1196    195 LGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  552 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELD 631
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  632 AQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISIL 711
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  712 HEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 790
Cdd:COG1196    434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  791 EENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARL 866
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  867 KEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQ 946
Cdd:COG1196    594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  947 VQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELV--CTSRDKADAILARLSQCQR 1024
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAleEQLEAEREELLEELLEEEE 746

                          570       580
                   ....*....|....*....|....*....
gi 1907199025 1025 HTATVGEALLRRMGQVSELEAQLTQLTEE 1053
Cdd:COG1196    747 LLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 447-1153 3.92e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 91.67  E-value: 3.92e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  447 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 526
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  527 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 605
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  606 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 678
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  679 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 755
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  756 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 826
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  827 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 882
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  883 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 955
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  956 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1025
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1026 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1105
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025 1106 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1153
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 142-930 2.92e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 2.92e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  142 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 216
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  217 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 295
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  296 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 375
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  376 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 455
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  456 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALE---------AELEEQRRHHQREVGSISEQ---------- 516
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEnlegfsegvKALLKNQSGLSGILGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  517 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 566
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  567 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 628
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  629 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 708
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  709 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 788
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  789 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 865
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  866 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 930
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
PTZ00121 PTZ00121
MAEBL; Provisional
 171-818 1.39e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.10  E-value: 1.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  171 QGEELREQKE--KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNS 248
Cdd:PTZ00121  1189 KAEELRKAEDarKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARR 1268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  249 EEQVAALQKLHAEELaSKEQELSRRLEARE----RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTE 324
Cdd:PTZ00121  1269 QAAIKAEEARKADEL-KKAEEKKKADEAKKaeekKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  325 SENKLQELGQEAEAYRtrilELETSLEKSLQESKTQSEhlAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTER 404
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAE----EKAEAAEKKKEEAKKKAD--AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD 1421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  405 LQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLD----KKQMELESVSSELSEALRARDQLAEE 480
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKadeaKKKAEEAKKADEAKKKAEEAKKKADE 1501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  481 L---SVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLE 557
Cdd:PTZ00121  1502 AkkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR 1581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  558 AHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQV 637
Cdd:PTZ00121  1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  638 QQLERQRSELEEKVRSlaqlqdSQLKNSTVEKEQARQSLMEKeniilqmrEEQAKEIEILKQTLSSKEesisilhEEYET 717
Cdd:PTZ00121  1662 KAAEEAKKAEEDKKKA------EEAKKAEEDEKKAAEALKKE--------AEEAKKAEELKKKEAEEK-------KKAEE 1720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 KFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQfnaQILEMAQANSAGISDTVSRLEENQRQQ 797
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK---KAEEIRKEKEAVIEEELDEEDEKRRME 1795

                          650       660
                   ....*....|....*....|.
gi 1907199025  798 IESLTGAHQRKLDDVIEAWEK 818
Cdd:PTZ00121  1796 VDKKIKDIFDNFANIIEGGKE 1816
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 329-969 2.35e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  329 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 408
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  409 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 486
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  487 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 565
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  566 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 645
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  646 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 717
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 785
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  786 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 865
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  866 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 916
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  917 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 969
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1467 1.54e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  773 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 847
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  848 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 927
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  928 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1007
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1008 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1083
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1084 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1153
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1154 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1209
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1210 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1273
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1274 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1340
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1341 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1420
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199025 1421 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1243-1911 1.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1243 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1322
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1323 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1402
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1403 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1482
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1483 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1559
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1560 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1612
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1613 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1675
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1676 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1755
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1756 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 1835
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1836 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 1910
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199025 1911 A 1911
Cdd:TIGR02168  910 R 910
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1604-1908 8.20e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 8.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1604 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1683
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1684 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 1763
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1764 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 1843
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025 1844 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 1908
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
PTZ00121 PTZ00121
MAEBL; Provisional
 1194-1910 1.61e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1194 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1272
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1273 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1351
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1352 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1427
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1428 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1507
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1508 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1587
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1588 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1667
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1668 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1746
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1747 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 1821
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1822 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 1894
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907199025 1895 EQVHNLEDRLKRYEKN 1910
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1936-1979 5.46e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.46e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199025  1936 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 1979
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1039-1467 5.77e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.13  E-value: 5.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1039 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1108
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1109 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1184
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1185 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1260
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1261 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1329
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1330 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1399
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025 1400 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
747-1151 7.01e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  747 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTGAhqrklDDVIEAWEKKLsqqaae 826
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRDEA-----DEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  827 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 906
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  907 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 973
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  974 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1019
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1020 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1099
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025 1100 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1151
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 607-1422 1.93e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  607 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 686
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  687 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 766
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  767 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 842
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  843 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 921
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  922 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 998
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  999 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1070
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1071 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1148
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1149 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1227
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1228 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1307
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1308 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1384
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1907199025 1385 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1422
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1051-1263 5.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1051 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1130
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1131 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1199
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199025 1200 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1263
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 1937-1976 2.00e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.50  E-value: 2.00e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907199025 1937 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 1976
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1069-1864 2.14e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1069 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1144
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1145 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1224
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1225 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1304
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1305 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1384
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1385 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1464
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1465 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1542
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1543 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1622
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1623 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1702
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1703 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 1782
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1783 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 1862
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907199025 1863 TK 1864
Cdd:pfam02463  962 NK 963
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1212-1909 7.23e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 7.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1212 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1291
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1292 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1371
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1372 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1449
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1450 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1524
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1525 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1604
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1605 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSqQEMDGENKCVEVLEDRPEENSQSHEIQSNVG 1684
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKAT-LEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1685 TVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQL 1762
Cdd:pfam02463  644 KESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1763 MREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDL 1842
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025 1843 QTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 1909
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 356-600 1.87e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  356 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 432
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  433 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 508
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  509 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 588
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907199025  589 GAyEEQLAQMQQ 600
Cdd:NF012221  1757 AA-ENKANQAQA 1767
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1687-1797 9.33e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 9.33e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  1687 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 1759
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907199025  1760 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 1797
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
 
Name Accession Description Interval E-value
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 155-736 2.93e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 2.93e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  155 EDEIAQLRSHIKQMTTQGE------ELREQKEKSE-RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV-ERASEEER 226
Cdd:COG1196    192 EDILGELERQLEPLERQAEkaeryrELKEELKELEaELLLLKLRELEAELEELEAELEELEAELEELEAELaELEAELEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  227 LRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQ 306
Cdd:COG1196    272 LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  307 ESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKHNKELTALAEQH 386
Cdd:COG1196    352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE-ALLERLERLEEELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  387 RTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK---KQMELESV 463
Cdd:COG1196    431 AELEEEEEEEEEAL--EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeaeADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  464 SSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ--QELTVRRAEKALKDELSRLGALLDE 541
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRARAAL 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  542 RDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMET 621
Cdd:COG1196    589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG----SLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  622 HKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTL 701
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199025  702 SSKEESISILHEEYETKFKNQEKRMEKIKQKAKEM 736
Cdd:COG1196    745 EELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 474-1053 1.03e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 93.46  E-value: 1.03e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  474 RDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEL--TVRRAEKALKDELSRLGALLDERDEHLRERQA 551
Cdd:COG1196    195 LGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  552 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELD 631
Cdd:COG1196    275 ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  632 AQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISIL 711
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELE-ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  712 HEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK-KELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 790
Cdd:COG1196    434 EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAlLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  791 EENQRQQIESLTGAHQR----KLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARL 866
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIgveaAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALA 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  867 KEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQsqvekleADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQ 946
Cdd:COG1196    594 RGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA-------ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  947 VQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELV--CTSRDKADAILARLSQCQR 1024
Cdd:COG1196    667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAleEQLEAEREELLEELLEEEE 746

                          570       580
                   ....*....|....*....|....*....
gi 1907199025 1025 HTATVGEALLRRMGQVSELEAQLTQLTEE 1053
Cdd:COG1196    747 LLEEEALEELPEPPDLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 113-648 3.69e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 3.69e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  113 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQkEKSERAAFEELEK 192
Cdd:COG1196    229 LLLLKLRELEAELEELEAELEE-----LEAELEELEAELAELEAELEELRLELEELELELEEAQAE-EYELLAELARLEQ 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  193 ALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAAsmAKKNSEEQVAALQKLHAEELASKEQELSR 272
Cdd:COG1196    303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEE--ELEEAEAELAEAEEALLEAEAELAEAEEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  273 RLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEK 352
Cdd:COG1196    381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  353 SLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQH----------------QAAV 416
Cdd:COG1196    461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavavligveaayEAAL 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  417 EELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALE 496
Cdd:COG1196    541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  497 AELEEQRRHHQREVGSI----SEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALA 572
Cdd:COG1196    621 TLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  573 KLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQ----VVEMETHKKHVCEELDAQRAQVQQLERQRSELE 648
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEeeelLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 447-1153 3.92e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 91.67  E-value: 3.92e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  447 EKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRGDADKMkQALEAELEEQRRHHQREVGSISEQQELTVRRAEK 526
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLERLRRE----REKAERY-QALLKEKREYEGYELLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  527 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 605
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVkEKIGELEAEIASLERSIAEKERELEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  606 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQ----RSELEEKVRSLAQLQDsQLKNSTVEKEQA---RQSLME 678
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEEledlRAELEEVDKEFAETRD-ELKDYREKLEKLkreINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  679 KENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA---KLKKELE 755
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  756 NTVLELSQKEKQ---------FNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 826
Cdd:TIGR02169  487 KLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  827 LRDKHA--------EQMEEKEQGLGELRQK------VRIVQSEKEELTKEVARLKEAVSGQDVALA----------GLQG 882
Cdd:TIGR02169  567 LKRRKAgratflplNKMRDERRDLSILSEDgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAArrlmgkyrmvTLEG 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  883 QLEQKSAVIVSLSERESQLQS-------QVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQ 955
Cdd:TIGR02169  647 ELFEKSGAMTGGSRAPRGGILfsrsepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  956 SCKSLHELSK----------KSLEDKSLNLKSLLEELASQLDSRcERTKALLEAKTNELvctsrdKADAILARLSQCQRH 1025
Cdd:TIGR02169  727 QLEQEEEKLKerleeleedlSSLEQEIENVKSELKELEARIEEL-EEDLHKLEEALNDL------EARLSHSRIPEIQAE 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1026 TATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASE 1105
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025 1106 KESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLE 1153
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLE 927
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 210-802 1.45e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 89.61  E-value: 1.45e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  210 EMDEQMKAVERASE--EERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLhAEELASKEQELSRRLEARERELQE---- 283
Cdd:COG1196    197 ELERQLEPLERQAEkaERYRELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEElrle 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  284 --QMRIALEKSRSEYLKLTQEKEQ--QESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKT 359
Cdd:COG1196    276 leELELELEEAQAEEYELLAELARleQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  360 QSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLfq 439
Cdd:COG1196    356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  440 ahiqdmnektLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRgdadkmkqALEAELEEQRRHHQREVGSISEQQEL 519
Cdd:COG1196    434 ----------EEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL--------EEAALLEAALAELLEELAEAAARLLL 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  520 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 599
Cdd:COG1196    496 LLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  600 QKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 679
Cdd:COG1196    576 FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  680 ENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL 759
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE 735

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907199025  760 ELSQKEKQFNAQILEMAQANSAGISDtvsrlEENQRQQIESLT 802
Cdd:COG1196    736 ELLEELLEEEELLEEEALEELPEPPD-----LEELERELERLE 773
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 324-1161 4.43e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 4.43e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  324 ESENKLQElgqeAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALA---EQHRTEVEGLQQQQDSL 400
Cdd:TIGR02168  176 ETERKLER----TRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVlrlEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  401 WTER--LQSLSQQHQAAVEELReKYQQEKDALLKEKESLFQAHIQDMNEKTL------EKLDKKQMELESVSSELSEALR 472
Cdd:TIGR02168  252 EEELeeLTAELQELEEKLEELR-LEVSELEEEIEELQKELYALANEISRLEQqkqilrERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  473 ARDQLAEELsvlrgdadkmkQALEAELEEQRRHHQREVGSISEQQELTV--RRAEKALKDELSRLGALLDERDEHLRERQ 550
Cdd:TIGR02168  331 KLDELAEEL-----------AELEEKLEELKEELESLEAELEELEAELEelESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  551 ARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAR-----EQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKH 625
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  626 VCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNS----------TVEKEQARQ---SLMEKENIILQMREEQAK 692
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSgilgvlseliSVDEGYEAAieaALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  693 E-IEILKQTLSSKE---ESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL----------------LDQEAKLKK 752
Cdd:TIGR02168  560 KaIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvddLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  753 ELENTVLELSQKEKQFNAQILeMAQANSAGISDTVSRLEE--NQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAAELRDK 830
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGV-ITGGSAKTNSSILERRREieELEEKIEELEEK-IAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  831 HAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEA 910
Cdd:TIGR02168  718 RKE-LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  911 DLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhELSKKSLEDKSLNLKSLLEELASqldsrc 990
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL-------EDLEEQIEELSEDIESLAAEIEE------ 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  991 ertkalLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEE 1070
Cdd:TIGR02168  864 ------LEELIEEL----ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1071 KEKQIKTMKADI--EGLLTEKEALQQEGGQQRQAASEKEScITQLKKELAE----NINAVtllrEELSEKKSEIASLSKQ 1144
Cdd:TIGR02168  934 LEVRIDNLQERLseEYSLTLEEAEALENKIEDDEEEARRR-LKRLENKIKElgpvNLAAI----EEYEELKERYDFLTAQ 1008

                          890       900
                   ....*....|....*....|
gi 1907199025 1145 LSDLG---AQLESSISPSDK 1161
Cdd:TIGR02168 1009 KEDLTeakETLEEAIEEIDR 1028
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 142-930 2.92e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 2.92e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  142 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER-----AAFEELEKALSTAQKTEDAQRRMKMEMDEQMK 216
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykelkAELRELELALLVLRLEELREELEELQEELKEA 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  217 AVERASEEERLR-LQHELSRVRQEAASMakknsEEQVAALQKlhaeELASKEQELSrRLEARERELQEQMRIALEKsrSE 295
Cdd:TIGR02168  252 EEELEELTAELQeLEEKLEELRLEVSEL-----EEEIEELQK----ELYALANEIS-RLEQQKQILRERLANLERQ--LE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  296 YLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvHLEAEKNKH 375
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  376 NKELTALaeqhRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALlkekeslfqahiqdmnEKTLEKLDK 455
Cdd:TIGR02168  399 NNEIERL----EARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL----------------EELQEELER 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  456 KQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALE---------AELEEQRRHHQREVGSISEQ---------- 516
Cdd:TIGR02168  459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEnlegfsegvKALLKNQSGLSGILGVLSELisvdegyeaa 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  517 ---------QELTVRRAEKALKD---------------ELSRL-GALLDERDEHLRERQARVQDLEAHLQKSAGE----- 566
Cdd:TIGR02168  539 ieaalggrlQAVVVENLNAAKKAiaflkqnelgrvtflPLDSIkGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  567 ------------LQQALAKLDLLHSEQSAAREQA------GAYEEQLAQMQQKVLDLETEKSLLTKQVVEMEthkkhvcE 628
Cdd:TIGR02168  619 syllggvlvvddLDNALELAKKLRPGYRIVTLDGdlvrpgGVITGGSAKTNSSILERRREIEELEEKIEELE-------E 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  629 ELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESI 708
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ-LEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  709 silhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEkqfnaQILEMAQANSAGISDTVS 788
Cdd:TIGR02168  771 ----EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR-----ERLESLERRIAATERRLE 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  789 RLE---ENQRQQIESLTGAhQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVAR 865
Cdd:TIGR02168  842 DLEeqiEELSEDIESLAAE-IEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  866 LKEAVSGQDVALAGLQGQLEQksaVIVSLSERESQLQSQVEKLEADLGCSLSEklsLQEELAELK 930
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDN---LQERLSEEYSLTLEEAEALENKIEDDEEE---ARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 515-1461 3.56e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 3.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  515 EQQELTVRRAEKALKDeLSRLGALLDERDEHLR--ERQARVQDLEAHLQKSAGELQQALAKLDLLhseqsAAREQAGAYE 592
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKslERQAEKAERYKELKAELRELELALLVLRLE-----ELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  593 EQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQlQDSQLKNSTVEKEQA 672
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE-RLANLERQLEELEAQ 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  673 RQSLMEKENIILQMREEQAKEIEILKQTLsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 752
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEEL----ESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  753 ELENTVLELSQKEkqfnaqilEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKkLSQQAAELRdkha 832
Cdd:TIGR02168  401 EIERLEARLERLE--------DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER-LEEALEELR---- 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  833 EQMEEKEQGLGELRQKVRIVQSEKEELtkevARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSER---ESQLQSQVEK-L 908
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEAAIEAaL 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  909 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTG----QVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAS 984
Cdd:TIGR02168  544 GGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLG 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  985 QLdsrcertkalleaktneLVCTSRDKADAILARLSQCQRHTATVGEaLLRRMGQVSELEAQLTQLTEEQRtlkssfqqv 1064
Cdd:TIGR02168  624 GV-----------------LVVDDLDNALELAKKLRPGYRIVTLDGD-LVRPGGVITGGSAKTNSSILERR--------- 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1065 tNQLEEKEKQIKTMKADIEGLLTEKEALqqeggqqRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1144
Cdd:TIGR02168  677 -REIEELEEKIEELEEKIAELEKALAEL-------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1145 LSDLGAQLEssispsdKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1224
Cdd:TIGR02168  749 IAQLSKELT-------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1225 HQSTIKDLQAQLDVKATDAREKEEQICLLKEDLdrqnkkfECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEdcvt 1304
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDI-------ESLAAEIEELEELIEELESELEALLNERASLEEALA---- 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1305 QRKKEVESLNETLKNYNQQRDTehsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLeaelgtVKKELEHVNSSV 1384
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRSE----LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE------YSLTLEEAEALE 960

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025 1385 KSRDGELKALEDKLelesaakvelkRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLED 1461
Cdd:TIGR02168  961 NKIEDDEEEARRRL-----------KRLENKIKELGPVNLAAIEE-----YEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 634-1466 8.95e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 8.95e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  634 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQaKEIEILKQTLSSKEESISILHE 713
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEEL-EELTAELQELEEKLEELRLEVS 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  714 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagisdtvsrleen 793
Cdd:TIGR02168  278 ELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  794 QRQQIESLTGAHQRKLDDVIEAWEKklsQQAAELRdkhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQ 873
Cdd:TIGR02168  342 LEEKLEELKEELESLEAELEELEAE---LEELESR------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  874 DVALAGLQGQLEQKSAVIVSLSEREsqLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKE 953
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  954 LQSCKSLHEL------SKKSLEDKSLNLKSLLEELASQLDSRCERTKAL---LEAKTNELVCTSRDKADAILARLSQCQR 1024
Cdd:TIGR02168  491 LDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVDEGYEAAIeaaLGGRLQAVVVENLNAAKKAIAFLKQNEL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1025 HTATVGEALLRRmgqvselEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQ--- 1101
Cdd:TIGR02168  571 GRVTFLPLDSIK-------GTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlrp 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1102 --------------------AASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDK 1161
Cdd:TIGR02168  644 gyrivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1162 AEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKAT 1241
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1242 DAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYN 1321
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1322 QQRdtehsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgelkaledklele 1401
Cdd:TIGR02168  884 SLE--------EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE----------------------- 932

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025 1402 saakvelkrKAEQKIAairkQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNL 1466
Cdd:TIGR02168  933 ---------GLEVRID----NLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 171-818 1.39e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.10  E-value: 1.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  171 QGEELREQKE--KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNS 248
Cdd:PTZ00121  1189 KAEELRKAEDarKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARR 1268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  249 EEQVAALQKLHAEELaSKEQELSRRLEARE----RELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTE 324
Cdd:PTZ00121  1269 QAAIKAEEARKADEL-KKAEEKKKADEAKKaeekKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEA 1347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  325 SENKLQELGQEAEAYRtrilELETSLEKSLQESKTQSEhlAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTER 404
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAE----EKAEAAEKKKEEAKKKAD--AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD 1421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  405 LQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLD----KKQMELESVSSELSEALRARDQLAEE 480
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKadeaKKKAEEAKKADEAKKKAEEAKKKADE 1501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  481 L---SVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLE 557
Cdd:PTZ00121  1502 AkkaAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALR 1581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  558 AHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQV 637
Cdd:PTZ00121  1582 KAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKI 1661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  638 QQLERQRSELEEKVRSlaqlqdSQLKNSTVEKEQARQSLMEKeniilqmrEEQAKEIEILKQTLSSKEesisilhEEYET 717
Cdd:PTZ00121  1662 KAAEEAKKAEEDKKKA------EEAKKAEEDEKKAAEALKKE--------AEEAKKAEELKKKEAEEK-------KKAEE 1720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 KFKNQEKRMEKIKQKAKEMQETKKKLldQEAKLKKELENTVLELSQKEKQfnaQILEMAQANSAGISDTVSRLEENQRQQ 797
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAKKEAEEDKKKA--EEAKKDEEEKKKIAHLKKEEEK---KAEEIRKEKEAVIEEELDEEDEKRRME 1795

                          650       660
                   ....*....|....*....|.
gi 1907199025  798 IESLTGAHQRKLDDVIEAWEK 818
Cdd:PTZ00121  1796 VDKKIKDIFDNFANIIEGGKE 1816
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 329-969 2.35e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  329 LQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaekNKHNKELTALAEQHRTEVEGLQQQQDSLWTERlQSL 408
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLL-------QQHQDRIEQLISEHEVEITGLTEKASSARSQA-NSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  409 SQQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEElsvlRG 486
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLsdLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQE----SG 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  487 DADKMKQALEAELeeqrrhHQREvgsiseqQELTVRRAE-KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAG 565
Cdd:pfam15921  374 NLDDQLQKLLADL------HKRE-------KELSLEKEQnKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKS 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  566 ELQqalakldllhseqsaareqaGAYEEQLAQMQQKVLDLETEKSLlTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 645
Cdd:pfam15921  441 ECQ--------------------GQMERQMAAIQGKNESLEKVSSL-TAQLESTKEMLRKVVEELTAKKMTLESSERTVS 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  646 EL----EEKVRSLaqlqdsQLKNSTVEKEQARQSLMEKENIILQMREEQAK----EIEILKQTLSSKEESISILHEEyet 717
Cdd:pfam15921  500 DLtaslQEKERAI------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRnvqtECEALKLQMAEKDKVIEILRQQ--- 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 kfknqekrMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ----------KEKQFNAQI--LEMAQANSAGISD 785
Cdd:pfam15921  571 --------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkkdaKIRELEARVsdLELEKVKLVNAGS 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  786 TVSRLEENQRQQIESLTGAHQRKLDDVieaweKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEElTKEVAR 865
Cdd:pfam15921  643 ERLRAVKDIKQERDQLLNEVKTSRNEL-----NSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQ-TRNTLK 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  866 LKEAVSGQDVALA-GLQGQLEQKSAVIVSL----------------------------SERESQLQSQVEKLEADLGCSL 916
Cdd:pfam15921  717 SMEGSDGHAMKVAmGMQKQITAKRGQIDALqskiqfleeamtnankekhflkeeknklSQELSTVATEKNKMAGELEVLR 796

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  917 SEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLE 969
Cdd:pfam15921  797 SQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
PTZ00121 PTZ00121
MAEBL; Provisional
 173-838 2.57e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.95  E-value: 2.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  173 EELREQKEKSERAAFEELEKA--LSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEE 250
Cdd:PTZ00121  1143 EEARKAEDAKRVEIARKAEDArkAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  251 QVAALQKLHAEELASKEQELSRRLEARERELQEQMRIAL--------------EKSRSEYLKLTQEKEQ-----QESLAL 311
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARmahfarrqaaikaeEARKADELKKAEEKKKadeakKAEEKK 1302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  312 EELELQKKAiltESENKLQELGQEAEAYRTRILELETSLE---KSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRT 388
Cdd:PTZ00121  1303 KADEAKKKA---EEAKKADEAKKKAEEAKKKADAAKKKAEeakKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK 1379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  389 EVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELS 468
Cdd:PTZ00121  1380 ADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  469 EALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvRRAEKALKDELSRLGALLDERDEHLRE 548
Cdd:PTZ00121  1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK---KKADEAKKAEEAKKADEAKKAEEAKKA 1536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  549 RQARvqdlEAHLQKSAGELQQAlakLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL-ETEKSLLTKQVVEMETHKKHVC 627
Cdd:PTZ00121  1537 DEAK----KAEEKKKADELKKA---EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKA 1609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  628 EELDAQRAQVQQLERQRSELEEKvrslaQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEEs 707
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEK-----KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA- 1683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  708 isilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQAnsagisdtv 787
Cdd:PTZ00121  1684 -----EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA--------- 1749

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  788 sRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEK 838
Cdd:PTZ00121  1750 -KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 151-871 4.25e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 4.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  151 LELKEDEIAQLRSHIKQMTTQGEELREQKEKSE------RAAFEELEKALSTAQKTEDAQR-------RMKMEMDEQMKA 217
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEekleelRLEVSELEEEIEELQKELYALAneisrleQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  218 VERASEEERLRLQHELSRV----RQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQE------QMRI 287
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLdelaEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETlrskvaQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  288 ALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE------KSLQESKTQS 361
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELErleealEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  362 EHLAVHLEAEKNKHNKELTALaEQHRTEVEGLQQQQDSLWTERLQsLSQQHQAAVE--ELREKYQQEKDALLKE------ 433
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG-LSGILGVLSEliSVDEGYEAAIEAALGGrlqavv 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  434 ---------------KESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGD-------ADKM 491
Cdd:TIGR02168  552 venlnaakkaiaflkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDL 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  492 KQALEaeleeQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALldERDEHLRERQARVQDLEAHLQKSAGELQQAL 571
Cdd:TIGR02168  632 DNALE-----LAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  572 AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKV 651
Cdd:TIGR02168  705 KELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  652 RSLAQLQDSQLKNSTVEKEQ-------------ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYEtk 718
Cdd:TIGR02168  785 EELEAQIEQLKEELKALREAldelraeltllneEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-- 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  719 fkNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNA--QILEMAQANSAGISDTVSRLEENQRQ 796
Cdd:TIGR02168  863 --ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSElrRELEELREKLAQLELRLEGLEVRIDN 940

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  797 QIESLTGAHQRKLDDVIEAWEKKLSQQaAELRDKhAEQMEEKEQGLG-----------ELRQKVRIVQSEKEELTKEVAR 865
Cdd:TIGR02168  941 LQERLSEEYSLTLEEAEALENKIEDDE-EEARRR-LKRLENKIKELGpvnlaaieeyeELKERYDFLTAQKEDLTEAKET 1018


                   ....*.
gi 1907199025  866 LKEAVS 871
Cdd:TIGR02168 1019 LEEAIE 1024
PTZ00121 PTZ00121
MAEBL; Provisional
 152-863 4.33e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.18  E-value: 4.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  152 ELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAafEELEKAlSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRlQH 231
Cdd:PTZ00121  1091 EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKA--EDARKA-EEARKAEDARKAEEARKAEDAKRVEIARKAEDAR-KA 1166

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  232 ELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERE---LQEQMRIALEKSRSEYLKLTQEKEQQES 308
Cdd:PTZ00121  1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEearKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  309 LALEELELQKKAILTESENKLQELGQEAEAYRtRILELETSLEKSLQESKTQSEHL----AVHLEAEKNKHNKELTALAE 384
Cdd:PTZ00121  1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEAR-KADELKKAEEKKKADEAKKAEEKkkadEAKKKAEEAKKADEAKKKAE 1325

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  385 QHRTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLK---EKESLFQAHIQDMNEKTLEKLDKKQMELE 461
Cdd:PTZ00121  1326 EAKKKADAAKKKAEEA-KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKkeeAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  462 SVSSELSEALRARDQLAEelsvLRGDADKMKQALEAELEEQRRHHQREVGSISEQQ---ELTVRRAEKALKDELSRLGAL 538
Cdd:PTZ00121  1405 KKADELKKAAAAKKKADE----AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkaEEAKKKAEEAKKADEAKKKAE 1480

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  539 LDERDEHLRERQARVQDLEAHLQKSAGELQQA----LAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTK 614
Cdd:PTZ00121  1481 EAKKADEAKKKAEEAKKKADEAKKAAEAKKKAdeakKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKA 1560

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  615 QVVEMETHKKHVCEE--LDAQRAQV-QQLERQRSELEEKV-RSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQ 690
Cdd:PTZ00121  1561 EEKKKAEEAKKAEEDknMALRKAEEaKKAEEARIEEVMKLyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKK 1640

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  691 AKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENtvLELSQKEKQFNA 770
Cdd:PTZ00121  1641 KEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE--LKKKEAEEKKKA 1718

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  771 QILEMAQANSAGISDTVSRLEENQRQQIESLTgahqrklddVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGE-LRQKV 849
Cdd:PTZ00121  1719 EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK---------KDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEeLDEED 1789

                          730
                   ....*....|....
gi 1907199025  850 RIVQSEKEELTKEV 863
Cdd:PTZ00121  1790 EKRRMEVDKKIKDI 1803
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 114-868 6.91e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.33  E-value: 6.91e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  114 LLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKA 193
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLT------------EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  194 LSTAQKTEDAQRRMKMEMDEQMKAVEraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRR 273
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLE--AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  274 LEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKS 353
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  354 LQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQQHQ 413
Cdd:TIGR02169  461 AADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  414 AAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELS 482
Cdd:TIGR02169  539 TAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  483 VLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLGALL 539
Cdd:TIGR02169  618 YVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  540 DERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEM 619
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  620 ETHKKHVCEELDA-----QRAQVQQLERQRSELEEKVRSL-AQLQ--DSQLKNSTVEKEQARQSLMEKENIILQM---RE 688
Cdd:TIGR02169  771 EEDLHKLEEALNDlearlSHSRIPEIQAELSKLEEEVSRIeARLReiEQKLNRLTLEKEYLEKEIQELQEQRIDLkeqIK 850

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  689 EQAKEIEILKQTLSSKEESIsilhEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQf 768
Cdd:TIGR02169  851 SIEKEIENLNGKKEELEEEL----EELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK- 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  769 naqiLEMAQANSAGISDTVSRLEEnqrqqiESLTGAHQRKLDDVIEAWEKKLsQQAAELRDKHAEQMEEKEQGLGELRQK 848
Cdd:TIGR02169  926 ----LEALEEELSEIEDPKGEDEE------IPEEELSLEDVQAELQRVEEEI-RALEPVNMLAIQEYEEVLKRLDELKEK 994

                          810       820
                   ....*....|....*....|
gi 1907199025  849 VRIVQSEKEELTKEVARLKE 868
Cdd:TIGR02169  995 RAKLEEERKAILERIEEYEK 1014
PTZ00121 PTZ00121
MAEBL; Provisional
 88-849 8.00e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 74.41  E-value: 8.00e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   88 QRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQ 167
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  168 MTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlrlqhELSRVRQEAASMAKKN 247
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEK-----KKEEAKKKADAAKKKA 1387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  248 SEEQVAALQKLHAEELASKEQELSRRLEARERElQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiltesen 327
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKA-DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA------- 1459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  328 klQELGQEAEAYRTrilelETSLEKSLQESKTQSEhlaVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQS 407
Cdd:PTZ00121  1460 --EEAKKKAEEAKK-----ADEAKKKAEEAKKADE---AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKK 1529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  408 LSQQHQAavEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESvsselsealrardqlaeelsvlrgd 487
Cdd:PTZ00121  1530 AEEAKKA--DEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK------------------------- 1582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  488 ADKMKQALEAELEEQRRHHQREvgsiseqqelTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGEL 567
Cdd:PTZ00121  1583 AEEAKKAEEARIEEVMKLYEEE----------KKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL 1652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  568 QQAlakldllHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL 647
Cdd:PTZ00121  1653 KKA-------EEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAE 1725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  648 EEKVRSLAQLQDSQLKNSTvEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESisiLHEEYETKFKNQEKRME 727
Cdd:PTZ00121  1726 EENKIKAEEAKKEAEEDKK-KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE---LDEEDEKRRMEVDKKIK 1801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  728 KIKQKAKEMQE----------TKKKLLDQEAKLKKELENTVLELSQKEKQ--FNAQILEMAQANSAGISDTVSRLEENQR 795
Cdd:PTZ00121  1802 DIFDNFANIIEggkegnlvinDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNNENGEDGNKEADFNKEKDLKEDDE 1881

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  796 QQIESLTGAHQRKLDDV-IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKV 849
Cdd:PTZ00121  1882 EEIEEADEIEKIDKDDIeREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEI 1936
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 142-970 8.61e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.95  E-value: 8.61e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  142 ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSER----------AAFEELEKALSTAQKTEDAQRRMKMEM 211
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERyqallkekreYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  212 DEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA-----EELASKEQELSRRLEARERELQE-QM 285
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEleaeiASLERSIAEKERELEDAEERLAKlEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  286 RIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKsLQESKTQSEHLA 365
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK-LKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  366 VHLEAEKnkhnKELTALAEQHRTEVEGLQQQQDSLWTERLQSlsqqhQAAVEELREKYQQEKDALLKEKESLFQahiqdm 445
Cdd:TIGR02169  409 DRLQEEL----QRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQELYD------ 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  446 nekTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEqrrhhQREVGSISEQQELTVRRAE 525
Cdd:TIGR02169  474 ---LKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT-----VAQLGSVGERYATAIEVAA 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  526 KAlkdelsRLGALLDERD-------EHLRERQA-----------RVQDLEAHLQKSAGELQQALAKLD------------ 575
Cdd:TIGR02169  546 GN------RLNNVVVEDDavakeaiELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEfdpkyepafkyv 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  576 ----LLHSEQSAAREQAGAYeeQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKV 651
Cdd:TIGR02169  620 fgdtLVVEDIEAARRLMGKY--RMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  652 RSlaqlQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQtlssKEESISILHEEYEtkfkNQEKRMEKIKQ 731
Cdd:TIGR02169  698 RR----IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE----LEEDLSSLEQEIE----NVKSELKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  732 KAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqILEMAQANSAGISDTVSRLEENQrQQIESLTGAHQRKLDD 811
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSK---LEEEVSRIEARLREIEQKLNRLT-LEKEYLEKEIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  812 VIEAWEKKLSQQAAELRDKhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVI 891
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLN--GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  892 VSLSERESQLQSQVEKLEADLGCSLSE----------KLSLQEELAELKLLADKSQLRVSELTgQVQAAEKELQSCKSLH 961
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKGEDEEIpeeelsledvQAELQRVEEEIRALEPVNMLAIQEYE-EVLKRLDELKEKRAKL 998


                   ....*....
gi 1907199025  962 ELSKKSLED 970
Cdd:TIGR02169  999 EEERKAILE 1007
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 773-1467 1.54e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 1.54e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  773 LEMAQANSAGISDTVSRLEEN-QRQQIESLTGAHQRKLDDVIEAWEKKLS----QQAAELRDKHAEQMEEKEQGLGELRQ 847
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlKSLERQAEKAERYKELKAELRELELALLvlrlEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  848 KVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELA 927
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  928 ELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELAsQLDSRCERTKALLEAKTNELVCT 1007
Cdd:TIGR02168  341 ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA-SLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1008 SRDKADAI----LARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1083
Cdd:TIGR02168  420 QQEIEELLkkleEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1084 GLLTEKEALQQEGGQQRQAASEKESCITQLKKE----------LAENINAVtlLREELSEKKSEIASLSKQLSDLGAQLE 1153
Cdd:TIGR02168  500 NLEGFSEGVKALLKNQSGLSGILGVLSELISVDegyeaaieaaLGGRLQAV--VVENLNAAKKAIAFLKQNELGRVTFLP 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1154 SSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDAL----------SKEKMSALEQV--------------DHWSN 1209
Cdd:TIGR02168  578 LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyllggvlvVDDLDNALELAkklrpgyrivtldgDLVRP 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1210 KFSEWK----------------KKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEV 1273
Cdd:TIGR02168  658 GGVITGgsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1274 RKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT---EHSGLVQRLQHLEE 1340
Cdd:TIGR02168  738 LEAEVEQLEeriaqlskelTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNE 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1341 LGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKsrdgELKALEDKLELESAAKVELKRKAEQKIAAIR 1420
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE----ELEELIEELESELEALLNERASLEEALALLR 893

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199025 1421 KQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:TIGR02168  894 SELEELSEE-----LRELESKRSELRRELEELREKLAQLELRLEGLE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 81-796 2.46e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.78  E-value: 2.46e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQ 160
Cdd:TIGR02168  281 EEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA------------EELAELEEKLEE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  161 LRSHIKQMTTQGEELREQKEKSERaAFEELEKALSTAQKtedAQRRMKMEMDEQMKAVERAsEEERLRLQHELSRVRQEA 240
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELES-RLEELEEQLETLRS---KVAQLELQIASLNNEIERL-EARLERLEDRRERLQQEI 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  241 ASMAKKNSEEQVAALQKLHAEELASKE--QELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQK 318
Cdd:TIGR02168  424 EELLKKLEEAELKELQAELEELEEELEelQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  319 -----KAILTESENKLQELGQEAEAYRTRiLELETSLEKSLQES-------KTQSEHLAVHLEAEKNKHNKELTALAEQH 386
Cdd:TIGR02168  504 fsegvKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAALGGRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIK 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  387 RTEVEGLQQQQDSLWTERLQSLSQqhqaaVEELREKYQQEKDALLKekeslfQAHIQDMNEKTLEKLDKKQMELESVSse 466
Cdd:TIGR02168  583 GTEIQGNDREILKNIEGFLGVAKD-----LVKFDPKLRKALSYLLG------GVLVVDDLDNALELAKKLRPGYRIVT-- 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  467 lsealRARDQLAEELSVLRGDADKMKQALEAELEeqRRHHQREVgSISEQQELTVRRAEKALKDELSRLGALLDERDEHL 546
Cdd:TIGR02168  650 -----LDGDLVRPGGVITGGSAKTNSSILERRRE--IEELEEKI-EELEEKIAELEKALAELRKELEELEEELEQLRKEL 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  547 RERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHV 626
Cdd:TIGR02168  722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  627 CEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQT--LSSK 704
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELeaLLNE 881

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  705 EESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ---ILEMAQANSA 781
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEyslTLEEAEALEN 961

                          730
                   ....*....|....*
gi 1907199025  782 GISDTVSRLEENQRQ 796
Cdd:TIGR02168  962 KIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1243-1911 1.54e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.54e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1243 AREKEEQICLLKEDLDRQNKKFECLKGEmevrKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQ 1322
Cdd:TIGR02168  220 AELRELELALLVLRLEELREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1323 qrdtEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEhvnssvksrdgELKALEDKLELES 1402
Cdd:TIGR02168  296 ----EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------ELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1403 AAKVELKRKAEQKIAAIRKQLLSQMEEktqryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESsphpEVPAVSRSMQ 1482
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSK-----VAQLELQIASLNNEIERLEARLERLEDRRERLQQ----EIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1483 SVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHV--- 1559
Cdd:TIGR02168  432 EAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVkal 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1560 ---------LIGCLPEELEEKMKCSLIVSQPMGE-----ETGNNTGVKQNWAS-------------VVDSVQKTLQEKEL 1612
Cdd:TIGR02168  512 lknqsglsgILGVLSELISVDEGYEAAIEAALGGrlqavVVENLNAAKKAIAFlkqnelgrvtflpLDSIKGTEIQGNDR 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1613 TCQALEQRVKELESDLVRERGAHRLEVEKL---------------TLKYEKSQSSQQEMDGE--NKCVEVLEDRPEENSQ 1675
Cdd:TIGR02168  592 EILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvddldnaleLAKKLRPGYRIVTLDGDlvRPGGVITGGSAKTNSS 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1676 SHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKH 1755
Cdd:TIGR02168  672 ILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1756 TSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRRTARRYEEiLDAREEEM 1835
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAAN-LRERLESL 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1836 TGKVTDLQTQLEELQKKYQQRLEQEESTKDSV-----TILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 1910
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIeeleeLIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   .
gi 1907199025 1911 A 1911
Cdd:TIGR02168  910 R 910
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 616-1467 3.23e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 3.23e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  616 VVEMETHKKHVCEELDAQRaqvQQLERQRSELEEKVRSLAQLQDsqlknstvEKEQARQSLmekeniILQMREEQAKEIE 695
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLRR--------EREKAERYQ------ALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  696 ILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQIlEM 775
Cdd:TIGR02169  228 LLKE-KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEI-AS 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  776 AQANSAGISDTVSRLEENQRQQIESLtgahqRKLDDVIEAWEKKLSQQAAElRDKHAEQMEEKEQGLGELRQKVRIVQSE 855
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEI-----DKLLAEIEELEREIEEERKR-RDKLTEEYAELKEELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  856 KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEElaelklladk 935
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE---------- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  936 sqlrVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsRDKADAI 1015
Cdd:TIGR02169  450 ----IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVL--KASIQGV 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1016 LARLSQC----QRHTATVGEALLRRMGQV----SELEAQLTQLTEEQRTLKSSFQQVTN-QLEEKEKQIKTMKADIE--- 1083
Cdd:TIGR02169  524 HGTVAQLgsvgERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLNKmRDERRDLSILSEDGVIGfav 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1084 --------------------GLLTEKEALQQEGGQQRQAA-----SEKESCITQLKKELAENINAVTLLREELSEKKSEI 1138
Cdd:TIGR02169  604 dlvefdpkyepafkyvfgdtLVVEDIEAARRLMGKYRMVTlegelFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1139 ASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKA 1218
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1219 QSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVV 1297
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1298 ELEDCVTQRKKEVESLN----------ETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLE 1367
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNgkkeeleeelEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1368 AELGTVKKELEHVNSSVKSrdgelkALEDKLELESAAKVELKRKA-EQKIAAIRKQLLSQMEEktqryAKDTENRLSELS 1446
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGE------DEEIPEEELSLEDVQAELQRvEEEIRALEPVNMLAIQE-----YEEVLKRLDELK 992

                          890       900
                   ....*....|....*....|.
gi 1907199025 1447 AQLKEREKQVHSLEDKLKNLE 1467
Cdd:TIGR02169  993 EKRAKLEEERKAILERIEEYE 1013
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 261-1098 4.92e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 4.92e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  261 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiLTESENKLQELGQEAEAYR 340
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENI-ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  341 TRILELETSLEKS---LQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVE 417
Cdd:TIGR02169  244 RQLASLEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  418 ELREKYQQEKDALLKEKESL---------FQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDA 488
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELereieeerkRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  489 DKMKQALEAELEEQRRHHQRevgsiseqqeltVRRAEKALKDELSRLGALlderdehlrerQARVQDLEAHLQKSAGELQ 568
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEE------------LADLNAAIAGIEAKINEL-----------EEEKEDKALEIKKQEWKLE 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  569 QALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKslltKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELE 648
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVG 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  649 EK-VRSLAQLQDSQLKNSTVEKEQARQSLMEkenIILQMREEQAKEIEILKqtLSSKEESISILHEE----YETKFKNQE 723
Cdd:TIGR02169  535 ERyATAIEVAAGNRLNNVVVEDDAVAKEAIE---LLKRRKAGRATFLPLNK--MRDERRDLSILSEDgvigFAVDLVEFD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  724 KRMEKIKQKA------KEMQETKKKLLDQEAKLKKELEntvlelsqkekqfnaqILEMAQANSAGiSDTVSRLEENQRQQ 797
Cdd:TIGR02169  610 PKYEPAFKYVfgdtlvVEDIEAARRLMGKYRMVTLEGE----------------LFEKSGAMTGG-SRAPRGGILFSRSE 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  798 IESLtgahqRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVAL 877
Cdd:TIGR02169  673 PAEL-----QRLRERLEGLKRELSSLQSELRRIENR-LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  878 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSlQEELAELKLLADKSQLRVSELTGQVQAAEKELQSc 957
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALN-DLEARLS-HSRIPEIQAELSKLEEEVSRIEARLREIEQKLNR- 823

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  958 kslHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALleaktnelvctsRDKADAILARLSQCQRHTATVGEALLRRM 1037
Cdd:TIGR02169  824 ---LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------------NGKKEELEEELEELEAALRDLESRLGDLK 888

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025 1038 GQVSELEAQLTQLTEEQRTLKSsfqqvtnQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQ 1098
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEA-------QIEKKRKRLSELKAKLEALEEELSEIEDPKGE 942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1604-1908 8.20e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 8.20e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1604 QKTLQEKELTCQALEQRVKELESDLVRErgahrlEVEKLTLKYEKSQSSQQEMdgENKCVEVLEDRPEENSQSHEIQSNV 1683
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEELEA------ELEELEAELEELEAELAEL--EAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1684 GTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQEldilkreceQEAEEKLKQEQEDLELKHTSTLKQLM 1763
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL---------EEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1764 REFNTQLAQKEQELERtvQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQ 1843
Cdd:COG1196    362 EAEEALLEAEAELAEA--EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025 1844 TQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYE 1908
Cdd:COG1196    440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1270-1851 1.25e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.25e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1270 EMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKV 1349
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE----YELLAELARLEQDIARLEERR 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1350 REAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEE 1429
Cdd:COG1196    312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1430 KTQryAKDTENRLSELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCM 1509
Cdd:COG1196    392 LRA--AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1510 LQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLED--HVLIGCLPEELEEKMKCSLIVSQPMGEETG 1587
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1588 NNtgvkqnwasVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1667
Cdd:COG1196    550 NI---------VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1668 DRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQE 1747
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1748 QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAEL-------------LESHQEETQQLHRKIAEK- 1813
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLeeealeelpeppdLEELERELERLEREIEALg 780

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1907199025 1814 ------EDDLRRTARRYeeildareEEMTGKVTDLQTQLEELQK 1851
Cdd:COG1196    781 pvnllaIEEYEELEERY--------DFLSEQREDLEEARETLEE 816
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 114-862 2.40e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.68  E-value: 2.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  114 LLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELRE-QKEKSERAAFEELEK 192
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSK 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  193 ALSTAQKTEDAQRRMKMEMDEQMKAVER------ASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASK 266
Cdd:pfam02463  258 QEIEKEEEKLAQVLKENKEEEKEKKLQEeelkllAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  267 EQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILEL 346
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  347 ETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQE 426
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEE 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  427 KDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHH 506
Cdd:pfam02463  498 RSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGA 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  507 QREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAARE 586
Cdd:pfam02463  578 RKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEG 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  587 QAgAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNST 666
Cdd:pfam02463  658 LA-EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINE 736

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  667 VEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMeKIKQKAKEMQETKKKLLDQ 746
Cdd:pfam02463  737 ELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL-KAQEEELRALEEELKEEAE 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  747 EAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAE 826
Cdd:pfam02463  816 LLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKE 895

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1907199025  827 LRDKHaEQMEEKEQGLGELRQKVRIVQSEKEELTKE 862
Cdd:pfam02463  896 KEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEIL 930
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 284-970 3.03e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.55  E-value: 3.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  284 QMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 363
Cdd:pfam12128  231 QAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFG--YKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  364 LAVHLEAEKNKHNKELTALAEQHR------TEVEGLQQQQDSLWTERLQSLSQQHqAAVEELREKYQQEKDALLKEKESL 437
Cdd:pfam12128  309 ELSAADAAVAKDRSELEALEDQHGafldadIETAAADQEQLPSWQSELENLEERL-KALTGKHQDVTAKYNRRRSKIKEQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  438 FQAHIQDMNEKTLEKLDKKQMELESVSSELsEALRA--RDQLAEELSVLRGDADKMKQAL------------EAELEEQR 503
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDL-QALESelREQLEAGKLEFNEEEYRLKSRLgelklrlnqataTPELLLQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  504 RHHQREVGSISEQQElTVRRAEKALKDELSRLGALLDERDEHLRERQARVQdleahlqksagELQQALAKLDLLHSEQSA 583
Cdd:pfam12128  467 ENFDERIERAREEQE-AANAEVERLQSELRQARKRRDQASEALRQASRRLE-----------ERQSALDELELQLFPQAG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  584 A-----REQAGAYEEQLAQMQQKVLDLETEkslLTKQVVEMETHKKHVCE--ELDAQRAQV-------QQLERQRSELEE 649
Cdd:pfam12128  535 TllhflRKEAPDWEQSIGKVISPELLHRTD---LDPEVWDGSVGGELNLYgvKLDLKRIDVpewaaseEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  650 KV---RSLAQLQDSQLKnstvekeQARQSLmekeniilqmrEEQAKEIEILKQTLSSKEESISILHEEYET-KFKNQEKR 725
Cdd:pfam12128  612 ALqsaREKQAAAEEQLV-------QANGEL-----------EKASREETFARTALKNARLDLRRLFDEKQSeKDKKNKAL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  726 MEKIKQKAKEMQ--ETKKKLLDQEAKL-KKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLT 802
Cdd:pfam12128  674 AERKDSANERLNslEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALE 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  803 GAHQRKLD--DVIEAWEKKLSQQAAELRDKhAEQMEEKEQGLGELRQKVRivqsekEELTKEVARLKEAVSGQDVALAGL 880
Cdd:pfam12128  754 TWYKRDLAslGVDPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQ------ETWLQRRPRLATQLSNIERAISEL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  881 QGQLEQKSA-VIVSLSERESQLQSQvEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSeLTGQVQAAEKELQSCKS 959
Cdd:pfam12128  827 QQQLARLIAdTKLRRAKLEMERKAS-EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDY 904

                          730
                   ....*....|.
gi 1907199025  960 LHELSKKSLED 970
Cdd:pfam12128  905 LSESVKKYVEH 915
PTZ00121 PTZ00121
MAEBL; Provisional
 81-552 4.71e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQ 160
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE 1422

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  161 LRSHIKQMTtQGEELREQKEKSERAafEELEKALSTAQKTEDAQRRMkmemDEQMKAVERASEEERLRLQHELSRVRQEA 240
Cdd:PTZ00121  1423 AKKKAEEKK-KADEAKKKAEEAKKA--DEAKKKAEEAKKAEEAKKKA----EEAKKADEAKKKAEEAKKADEAKKKAEEA 1495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  241 ---ASMAKKNSEEQVAALQKLHAEElASKEQELSRRLEARErelQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQ 317
Cdd:PTZ00121  1496 kkkADEAKKAAEAKKKADEAKKAEE-AKKADEAKKAEEAKK---ADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKK 1571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  318 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQ 397
Cdd:PTZ00121  1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  398 DSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQL 477
Cdd:PTZ00121  1652 LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK 1731

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  478 AEELSvlRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsrlgaLLDERDEHLRERQAR 552
Cdd:PTZ00121  1732 AEEAK--KEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE------ELDEEDEKRRMEVDK 1798
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1215-1906 7.32e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.23  E-value: 7.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1215 KKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKM---EKKECDLETALKT 1291
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLanlERQLEELEAQLEE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1292 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHsglvQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELG 1371
Cdd:TIGR02168  328 LESKLDELAEELAELEEKLEELKEELESLEAELEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1372 TVKKELEHVNSSVKSRDGELKALEDKLEL----ESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKdTENRLSELSA 1447
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEEaelkELQAELEELEEELEELQEELERLEEALEELREELEE-AEQALDAAER 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1448 QLKEREKQVHSLEDKLKNLE-------------SSPHPEVPAVSR------------------SMQSVAASPEQEAPDSQ 1496
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEgfsegvkallknqSGLSGILGVLSElisvdegyeaaieaalggRLQAVVVENLNAAKKAI 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1497 DCTHKACKERLCMLQRRLSEKEKL----LRRLEQGEGEARP-----SQPEAQHRALSGKLDCTR-----------ARQLE 1556
Cdd:TIGR02168  563 AFLKQNELGRVTFLPLDSIKGTEIqgndREILKNIEGFLGVakdlvKFDPKLRKALSYLLGGVLvvddldnalelAKKLR 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1557 DHVLIGCLPEEL---------EEKMKCSLIVSQpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESD 1627
Cdd:TIGR02168  643 PGYRIVTLDGDLvrpggvitgGSAKTNSSILER--RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1628 LVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLED-RPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK 1706
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1707 LSKEVARLQKELRALRREHQQeldilkreceqeAEEKLKQEQEDLELKhtstlKQLMREFNTQLAQKEQELERTVQEtID 1786
Cdd:TIGR02168  801 LREALDELRAELTLLNEEAAN------------LRERLESLERRIAAT-----ERRLEDLEEQIEELSEDIESLAAE-IE 862

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1787 KAQEVEAELLESHQEETQQLhrkiaEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKds 1866
Cdd:TIGR02168  863 ELEELIEELESELEALLNER-----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE-- 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025 1867 VTILELQTQLAQK--------TTLISDSKLKEQELREQVHNLEDRLKR 1906
Cdd:TIGR02168  936 VRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKE 983
PTZ00121 PTZ00121
MAEBL; Provisional
 1194-1910 1.61e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 1.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1194 SKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEME 1272
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDArKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1273 VRKSKMEKKEcdlETALKTQTAR-VVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVRE 1351
Cdd:PTZ00121  1163 ARKAEEARKA---EDAKKAEAARkAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1352 AE----ETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQkiaAIRKQLLSQM 1427
Cdd:PTZ00121  1240 EEakkaEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE---AKKKAEEAKK 1316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1428 EEKTQRYAKDTENRLSELSAQLKEREKQvhslEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERL 1507
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEAKKA----AEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK 1392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1508 CMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETG 1587
Cdd:PTZ00121  1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA 1472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1588 NNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLE 1667
Cdd:PTZ00121  1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1668 dRPEENSQSHEIQSnvgtVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-EKLKQ 1746
Cdd:PTZ00121  1553 -KAEELKKAEEKKK----AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKaEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1747 EQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE---AELLESHQEETQQLHRKIAEKEDDLRRTA-- 1821
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEel 1707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1822 -------RRYEEILDAREEEMTGKVTDLQTQLEElQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELR 1894
Cdd:PTZ00121  1708 kkkeaeeKKKAEELKKAEEENKIKAEEAKKEAEE-DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786

                          730
                   ....*....|....*.
gi 1907199025 1895 EQVHNLEDRLKRYEKN 1910
Cdd:PTZ00121  1787 EEDEKRRMEVDKKIKD 1802
PTZ00121 PTZ00121
MAEBL; Provisional
 1208-1868 1.64e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 1.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1208 SNKFSEWKKKAQSRLAQHQSTIKDLQAQLDV-KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKME----KKE 1282
Cdd:PTZ00121  1169 ARKAEDAKKAEAARKAEEVRKAEELRKAEDArKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEakkaEEE 1248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1283 CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGE--EKDNKVREAEETVLRLR 1360
Cdd:PTZ00121  1249 RNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAK 1328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1361 EHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEqkiAAIRKQLLSQMEEKTQRYAKDTEN 1440
Cdd:PTZ00121  1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD---AAKKKAEEKKKADEAKKKAEEDKK 1405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1441 RLSELSAQlKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKL 1520
Cdd:PTZ00121  1406 KADELKKA-AAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK 1484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1521 LRRLEQGEGEARPSQPEAQHRAlSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVV 1600
Cdd:PTZ00121  1485 ADEAKKKAEEAKKKADEAKKAA-EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEK 1563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1601 DSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQ 1680
Cdd:PTZ00121  1564 KKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEA 1643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1681 SNVGTVDGLRSDLESKLTGAERDKQKlSKEVARLQKELRALRREHQQELDILKRECEQ--EAEEKLKQEQEDLELKHTST 1758
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKK-AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEakKAEELKKKEAEEKKKAEELK 1722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1759 LKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGK 1838
Cdd:PTZ00121  1723 KAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802

                          650       660       670
                   ....*....|....*....|....*....|
gi 1907199025 1839 VTDLQTQLEELQKKYQQRLEQEESTKDSVT 1868
Cdd:PTZ00121  1803 IFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 80-760 1.76e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   80 AKTLEMLQQRVKRQ-ENLLQRCKETIGSHK---EQCALLLSEKEALQEQLDERLQELEkmkgmvitETKRQMLETLELKE 155
Cdd:TIGR02169  271 EQLLEELNKKIKDLgEEEQLRVKEKIGELEaeiASLERSIAEKERELEDAEERLAKLE--------AEIDKLLAEIEELE 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  156 DEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDE--QMKAVERASEEERLRLQHEL 233
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREinELKRELDRLQEELQRLSEEL 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  234 SRVRQEAASMAKKNSEEQVAALQKlhAEELASKEQELSRRLEARERELQEQMRI-----ALEKSRSEYLKLTQEKEQQES 308
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDK--ALEIKKQEWKLEQLAADLSKYEQELYDLkeeydRVEKELSKLQRELAEAEAQAR 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  309 LALEELELQKKAILTESEN------KLQELGQEAEAYrtrILELETSLEKSLQESKTQSEHLAV----HLEAEK------ 372
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASiqgvhgTVAQLGSVGERY---ATAIEVAAGNRLNNVVVEDDAVAKeaieLLKRRKagratf 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  373 ---NKHNKELTALAEQHRTEVEGL----------------QQQQDSLWTERLQS-------------------------- 407
Cdd:TIGR02169  578 lplNKMRDERRDLSILSEDGVIGFavdlvefdpkyepafkYVFGDTLVVEDIEAarrlmgkyrmvtlegelfeksgamtg 657

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  408 ------LSQQHQAAVEELREKYQQEKDALLKEKESLFQ--AHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAE 479
Cdd:TIGR02169  658 gsraprGGILFSRSEPAELQRLRERLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE 737

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  480 ELSVLRGDADKMKQALEAELEEQRRHHQRevgsISEQQEL--TVRRAEKALKDELSR-----LGALLDERDEHLRERQAR 552
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDlhKLEEALNDLEARLSHsripeIQAELSKLEEEVSRIEAR 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  553 VQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA 632
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE 893

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  633 QRAQVQQLERQRSELEEKVrslaQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKE--IEILKQTLSSKEESISI 710
Cdd:TIGR02169  894 LEAQLRELERKIEELEAQI----EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsLEDVQAELQRVEEEIRA 969

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  711 LHE---EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLE 760
Cdd:TIGR02169  970 LEPvnmLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 113-935 1.76e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.08  E-value: 1.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  113 LLLSEKEALQEQLDERLQELEKmkgmvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEK 192
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLAS-----LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  193 ALSTAQKTEDAQRRMKMEMDEQMKAVEraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSR 272
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLAKLE--AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  273 RLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEK 352
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  353 SLQE-SKTQSEHLAvhLEAEKNKHNKELTALAEQH----------RTEVEGLQQQQDSLWTER---------LQSLSQQH 412
Cdd:TIGR02169  460 LAADlSKYEQELYD--LKEEYDRVEKELSKLQRELaeaeaqarasEERVRGGRAVEEVLKASIqgvhgtvaqLGSVGERY 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  413 QAAVEEL-----------REKYQQEKDALLKEKEsLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEEL 481
Cdd:TIGR02169  538 ATAIEVAagnrlnnvvveDDAVAKEAIELLKRRK-AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAF 616

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  482 SVLRGDA---DKMKQA-----------LEAELEEQ--------RRHHQREVGSISEQQEL-TVRRAEKALKDELSRLGAL 538
Cdd:TIGR02169  617 KYVFGDTlvvEDIEAArrlmgkyrmvtLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQSE 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  539 LDERDEHLRERQARVQDLEAHLQKSAGELQQalakldlLHSEQSAAREQAGAYEEQLAQMQQKVLDLEtekslltkqvve 618
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLEQEIENVK------------ 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  619 methkkhvcEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNSTVEKEQArqslmekeniilqmrEEQAKEIEIL 697
Cdd:TIGR02169  758 ---------SELKELEARIEELEEDLHKLEEALNDLeARLSHSRIPEIQAELSKL---------------EEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  698 KQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFnaqilemaq 777
Cdd:TIGR02169  814 LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRL--------- 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  778 ansAGISDTVSRLEENQRQQiesltgahqrklddvieawEKKLSQQAAELrdkhaeqmEEKEQGLGELRQKVRIVQSEKE 857
Cdd:TIGR02169  885 ---GDLKKERDELEAQLREL-------------------ERKIEELEAQI--------EKKRKRLSELKAKLEALEEELS 934

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025  858 ELTKEVARLKEaVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADK 935
Cdd:TIGR02169  935 EIEDPKGEDEE-IPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
459-656 3.55e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.77  E-value: 3.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  459 ELESVSSELSEALRARDQLAEelsvLRGDADKMKQALE--AELEEQRRHHQREVGsisEQQELTVRRAEKALKDELSRLG 536
Cdd:COG4913    236 DLERAHEALEDAREQIELLEP----IRELAERYAAARErlAELEYLRAALRLWFA---QRRLELLEAELEELRAELARLE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  537 ALLDERDEHLRERQARVQDLEAHLQKSAGE-LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVL----DLETEKSL 611
Cdd:COG4913    309 AELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRARLEALLAALGLPLPasaeEFAALRAE 388

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907199025  612 LTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQ 656
Cdd:COG4913    389 AAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 157-752 3.72e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 58.60  E-value: 3.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  157 EIAQLRSHIKQMTTQgeelREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV 236
Cdd:pfam05557    3 ELIESKARLSQLQNE----KKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELN 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  237 RQEAASMAKKNSEEQVAALQKLHAEELAS-KEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELE 315
Cdd:pfam05557   79 RLKKKYLEALNKKLNEKESQLADAREVIScLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNL 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  316 LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHleaEKNKHNKELTALAEQHRTEVEGLQQ 395
Cdd:pfam05557  159 EKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSELARIPELEKELERLR---EHNKHLNENIENKLLLKEEVEDLKR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  396 QQDSlwterlQSLSQQHQAAVEELREKYQQEkdalLKEKESLFQAHIQDMNE--------KTLEKLDKKQME-LESVSSE 466
Cdd:pfam05557  236 KLER------EEKYREEAATLELEKEKLEQE----LQSWVKLAQDTGLNLRSpedlsrriEQLQQREIVLKEeNSSLTSS 305

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  467 LSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQELtVRRAEKALKDELSrlgalldeRDEHL 546
Cdd:pfam05557  306 ARQLEKARRELEQELAQYLKKIEDLNKKLK-RHKALVRRLQRRVLLLTKERDG-YRAILESYDKELT--------MSNYS 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  547 RERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVldlETEKSLLTKQVVEmethkkHV 626
Cdd:pfam05557  376 PQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQE---SLADPSYSKEEVD------SL 446

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  627 CEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVekeqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEE 706
Cdd:pfam05557  447 RRKLETLELERQRLREQKNELEMELERRCLQGDYDPKKTKV--------LHLSMNPAAEAYQQRKNQLEKLQAEIERLKR 518

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1907199025  707 SISILHEEYETKfknQEKRMEKIKQKAKEMQETKKKLLDQEAKLKK 752
Cdd:pfam05557  519 LLKKLEDDLEQV---LRLPETTSTMNFKEVLDLRKELESAELKNQR 561
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 587-1469 4.28e-08

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 58.90  E-value: 4.28e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  587 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRseleeKVRSLAQLQDSQLKNST 666
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR-----EIVKSYENELDPLKNRL 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  667 VEKEQARQSLMEKENII-------LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQET 739
Cdd:TIGR00606  255 KEIEHNLSKIMKLDNEIkalksrkKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  740 KKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVieaweKK 819
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEA-----KT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  820 LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSEres 899
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERE--- 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  900 qlQSQVEKlEADLGCSLSEKLSLQEELAELklladksqlrvseltgqvqaaekELQSCKSLHELSKKSLEDKSLNLKSLL 979
Cdd:TIGR00606  487 --LSKAEK-NSLTETLKKEVKSLQNEKADL-----------------------DRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  980 EELASQLDSRCERTKAlleaktnelvctsrdKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKS 1059
Cdd:TIGR00606  541 TKDKMDKDEQIRKIKS---------------RHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQ 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1060 SFQQVTNQLEEKEKQIKTMKADI------EGLLTEKEALQQE---GGQQRQAASEKESCITQLKKELAENINAVTLLREE 1130
Cdd:TIGR00606  606 NKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEiekSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1131 LSEKKSEIASLSKQLSDLgaqlesSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNK 1210
Cdd:TIGR00606  686 VFQTEAELQEFISDLQSK------LRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1211 FSEWKKKAQSRLAQHQSTIKDLQAQLDVKA--TDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLEta 1288
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTdvTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHE-- 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1289 LKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRlQHLEELGEEKDNKVREAEETVLRLREHVSSLEA 1368
Cdd:TIGR00606  838 LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR-QQFEEQLVELSTEVQSLIREIKDAKEQDSPLET 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1369 elgTVKKELEHVNSSVKSRDGELKALEDKLElesaakvELKRKAEQKIAAiRKQLLSQMEEKTQRYAKDTENRLSELSAQ 1448
Cdd:TIGR00606  917 ---FLEKDQQEKEELISSKETSNKKAQDKVN-------DIKEKVKNIHGY-MKDIENKIQDGKDDYLKQKETELNTVNAQ 985

                          890       900
                   ....*....|....*....|.
gi 1907199025 1449 LKEREKQVHSLEDKLKNLESS 1469
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQD 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1042-1857 5.06e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 5.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1042 ELEAQLTQLteEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENI 1121
Cdd:TIGR02168  217 ELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1122 NAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSAL 1201
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1202 EQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQL-DVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEK 1280
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLeRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1281 KECDLETALKTQTARVVELEDCVTQRKKEVESLN---ETLKNYNQQRDTEHSGLVQRLQHLEELGE---------EKDNK 1348
Cdd:TIGR02168  455 ELERLEEALEELREELEEAEQALDAAERELAQLQarlDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlseliSVDEG 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1349 VREAEETVlrLREHVSSLEAElgTVKKELEHVNSSVKSRDGELKALEdkLELESAAKVELKRKAEQKIAAIRKQLLSQME 1428
Cdd:TIGR02168  535 YEAAIEAA--LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1429 EKTQRYAKDTENRLS------------ELSAQLKEREKQVhSLEDKLknleSSPHPEVPAVSRSMQSVAASPEQEAPDSQ 1496
Cdd:TIGR02168  609 KFDPKLRKALSYLLGgvlvvddldnalELAKKLRPGYRIV-TLDGDL----VRPGGVITGGSAKTNSSILERRREIEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1497 DCThKACKERLCMLQRRLSEKEKLLRRLEQGEGEAR--PSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKC 1574
Cdd:TIGR02168  684 EKI-EELEEKIAELEKALAELRKELEELEEELEQLRkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1575 SLIVSQPMGEETGNNTGVKQNWASVVDSVQKtlqekeltcqaLEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQ 1654
Cdd:TIGR02168  763 IEELEERLEEAEEELAEAEAEIEELEAQIEQ-----------LKEELKALREALDELRAELTLLNEEAANLRERLESLER 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1655 EMDGENKCVEVLEDRPEENSQSHE-IQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALR---REHQQELD 1730
Cdd:TIGR02168  832 RIAATERRLEDLEEQIEELSEDIEsLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELESKRS 911

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1731 ILKRECE--QEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLaqkeQELERTVQETIDKAQEVEAElLESHQEETQQLHR 1808
Cdd:TIGR02168  912 ELRRELEelREKLAQLELRLEGLEVRIDNLQERLSEEYSLTL----EEAEALENKIEDDEEEARRR-LKRLENKIKELGP 986

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199025 1809 KIAEKEDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRL 1857
Cdd:TIGR02168  987 VNLAAIEEYEELKERYDF-LTAQKEDLTEAKETLEEAIEEIDREARERF 1034
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
1936-1979 5.46e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.46e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 1907199025  1936 PTEFEYLRKVMFEYMMGRET--KTMAKVITTVLKFPDDQAQKILER 1979
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1039-1467 5.77e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 58.13  E-value: 5.77e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1039 QVSELEAQLTQLTEEQRTLKSSFQQVTNQL---EEKEKQIKTMKADIEGL-------LTEKEALQQEGGQQRQAASEKES 1108
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETLEAEIEDLretiaetEREREELAEEVRDLRERLEELEE 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1109 CITQLKKELA---ENINAVTLLREELSEKKSEIA-SLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQ 1184
Cdd:PRK02224   294 ERDDLLAEAGlddADAEAVEARREELEDRDEELRdRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1185 ELSLKVDAlSKEKMSALE-QVDHWSNKFS---EWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLlKEDLDRQ 1260
Cdd:PRK02224   374 EAREAVED-RREEIEELEeEIEELRERFGdapVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE-AEALLEA 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1261 NKKFECLK-----------GEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQrKKEVESLNETLKNYNQQRDTEHS 1329
Cdd:PRK02224   452 GKCPECGQpvegsphvetiEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRE 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1330 GLVQRLQHLEEL----------GEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNsSVKSRDGELKALEDKLE 1399
Cdd:PRK02224   531 TIEEKRERAEELreraaeleaeAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIE 609

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025 1400 LESAAKVELKRKAEQKiaaiRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:PRK02224   610 RLREKREALAELNDER----RERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
232-757 6.91e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 6.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  232 ELSRVRQEAASMakknsEEQVAALQKLhaEELASKEQELSRRLEARERELQeqmrialeksrseylKLTQEKEQQESLAL 311
Cdd:COG4913    236 DLERAHEALEDA-----REQIELLEPI--RELAERYAAARERLAELEYLRA---------------ALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  312 EELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVE 391
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  392 GLQQQQDSLWteRLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHiqdmnektlEKLDKKQMELESVSSEL-SEA 470
Cdd:COG4913    374 PLPASAEEFA--ALRAEAAALLEALEEELEALEEALAEAEAALRDLRREL---------RELEAEIASLERRKSNIpARL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  471 LRARDQLAEELSV-------------LRGDADKMKQALEAELEEQRR------HHQREVGSISEQQELTVR-RAEKALKD 530
Cdd:COG4913    443 LALRDALAEALGLdeaelpfvgelieVRPEEERWRGAIERVLGGFALtllvppEHYAAALRWVNRLHLRGRlVYERVRTG 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  531 ELSRLGALLDER-----------------DEHLRERQARV-----QDLEAH--------LQKSAGEL------------- 567
Cdd:COG4913    523 LPDPERPRLDPDslagkldfkphpfrawlEAELGRRFDYVcvdspEELRRHpraitragQVKGNGTRhekddrrrirsry 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  568 ---QQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvemETHKKHVCEELDAQ--RAQVQQLER 642
Cdd:COG4913    603 vlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-------QRLAEYSWDEIDVAsaEREIAELEA 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  643 QRSELEEKVRSLAQLQD--SQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISI-LHEEYETKF 719
Cdd:COG4913    676 ELERLDASSDDLAALEEqlEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERF 755

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1907199025  720 KNQEKRmEKIKQKAKEMQETKKKLLDQEAKLKKELENT 757
Cdd:COG4913    756 AAALGD-AVERELRENLEERIDALRARLNRAEEELERA 792
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
747-1151 7.01e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.01e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  747 EAKLKKELENTVLELSQKEKQFNAQIlemaqansagisdtvSRLEENQRQQIESLTGAhqrklDDVIEAWEKKLsqqaae 826
Cdd:PRK02224   197 EEKEEKDLHERLNGLESELAELDEEI---------------ERYEEQREQARETRDEA-----DEVLEEHEERR------ 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  827 lrdkhaEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 906
Cdd:PRK02224   251 ------EELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  907 KLEADL-------GCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL------ 973
Cdd:PRK02224   325 ELRDRLeecrvaaQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdap 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  974 ----NLKSLLEELASQLD-----------------SRCERTKALLEA----------KTNELVCT---SRDKADAILARL 1019
Cdd:PRK02224   405 vdlgNAEDFLEELREERDelrereaeleatlrtarERVEEAEALLEAgkcpecgqpvEGSPHVETieeDRERVEELEAEL 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1020 SQCQRHTATVgEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ 1099
Cdd:PRK02224   485 EDLEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEA 563

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025 1100 RQAASEKESCITQLKKELAENINAVTLLR------EELSEKKSEIASLSKQLSDLGAQ 1151
Cdd:PRK02224   564 EEEAEEAREEVAELNSKLAELKERIESLErirtllAAIADAEDEIERLREKREALAEL 621
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 291-757 7.22e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.72  E-value: 7.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  291 KSRSEYLKLTQEKEQQESLALEELE--LQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE-SKTQSEHLAVH 367
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTeiKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNiDKIKNKLLKLE 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  368 LE----AEKNKHNKELTA----LAEQHRTEVEGLQQQQDSL---------WTERLQSLSQQHQAAVEELREKYQQ--EKD 428
Cdd:TIGR04523  201 LLlsnlKKKIQKNKSLESqiseLKKQNNQLKDNIEKKQQEInektteisnTQTQLNQLKDEQNKIKKQLSEKQKEleQNN 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  429 ALLKEKESLFQA-----------HIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKmKQALEA 497
Cdd:TIGR04523  281 KKIKELEKQLNQlkseisdlnnqKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTN-SESENS 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  498 ELEEQRRHHQREVGSISEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLL 577
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKN-LESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  578 HSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQL 657
Cdd:TIGR04523  439 NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  658 QDSQLKNS---TVEKEQARQSLMEKENIILQMREEQAKEIeiLKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAK 734
Cdd:TIGR04523  519 ISSLKEKIeklESEKKEKESKISDLEDELNKDDFELKKEN--LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEK 596

                          490       500
                   ....*....|....*....|....*.
gi 1907199025  735 EMQETKKKLLDQEAK---LKKELENT 757
Cdd:TIGR04523  597 EKKDLIKEIEEKEKKissLEKELEKA 622
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1304-1859 8.91e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 8.91e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1304 TQRKKEVESLNETLKNYNQQRDTEHsgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEA--------ELGTVKK 1375
Cdd:COG4913    268 RERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDELEAqirgnggdRLEQLER 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1376 ELEHVNSSVKSRDGELKALEDKLelesaAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQ 1455
Cdd:COG4913    346 EIERLERELEERERRRARLEALL-----AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1456 VHSLEDKLKNLESSP---HPEVPAVSRSMQSVAASPEQEAP--------DSQDCTHKACKER------LCML--QRRLS- 1515
Cdd:COG4913    421 LRELEAEIASLERRKsniPARLLALRDALAEALGLDEAELPfvgelievRPEEERWRGAIERvlggfaLTLLvpPEHYAa 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1516 -----EKEKLLRRL---EQGEGEARPSQPEAQHRALSGKLD----------------------CTRARQLEDH---VLIG 1562
Cdd:COG4913    501 alrwvNRLHLRGRLvyeRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawleaelgrrfdyvcVDSPEELRRHpraITRA 580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1563 CL---PEELEEKmkcslivsqpmgeetGNNTGVKQNWASVVDSVQKtLQEKELTCQALEQRVKELESDLVRERGAHRLEV 1639
Cdd:COG4913    581 GQvkgNGTRHEK---------------DDRRRIRSRYVLGFDNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQ 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1640 EKLTL--KYEKSQSSQQEMDGENKCVEVLEDRPEE----NSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVAR 1713
Cdd:COG4913    645 ERREAlqRLAEYSWDEIDVASAEREIAELEAELERldasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQ 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1714 LQKELRALRREHQQELDILKRECEQEAEEKLKQE-QEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVE 1792
Cdd:COG4913    725 AEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025 1793 AELLES--HQEETQQLHRKIaeKEDDLrrtARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQ 1859
Cdd:COG4913    805 ADLDADleSLPEYLALLDRL--EEDGL---PEYEERFKELLNENSIEFVADLLSKLRRAIREIKERIDP 868
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 716-1319 1.06e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  716 ETKFKNQEKRMEKI----KQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANSAGISD-TVSRL 790
Cdd:TIGR04523   32 DTEEKQLEKKLKTIknelKNKEKELKNLDKNLNKDEEK-INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDlSKINS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  791 EENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAV 870
Cdd:TIGR04523  111 EIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKE-LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  871 SGQDVALAglqgQLEQKSAVIVSLSERESQLQSQVEKLEadlgcslseklslqEELAELKLLADKSQLRVSELTGQVQAA 950
Cdd:TIGR04523  190 DKIKNKLL----KLELLLSNLKKKIQKNKSLESQISELK--------------KQNNQLKDNIEKKQQEINEKTTEISNT 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  951 EKELQSCKSLHELSKKSLEDKSLNL---KSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTA 1027
Cdd:TIGR04523  252 QTQLNQLKDEQNKIKKQLSEKQKELeqnNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1028 TVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKE 1107
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1108 SCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES-SISPSDKAEAISALSKQHEEQELQLQAQLQEL 1186
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNlDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1187 SLKV---DALSKEKMSALEQVDHWSNKFSEWKKKAQ---SRLAQHQSTIKDLQAQLDVKATDAREKeeqicLLKEDLDRQ 1260
Cdd:TIGR04523  492 KSKEkelKKLNEEKKELEEKVKDLTKKISSLKEKIEkleSEKKEKESKISDLEDELNKDDFELKKE-----NLEKEIDEK 566

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025 1261 NKKFECLKGEMEVRKSKMEKKE----------CDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1319
Cdd:TIGR04523  567 NKEIEELKQTQKSLKKKQEEKQelidqkekekKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1039-1469 1.10e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 1.10e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1039 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELA 1118
Cdd:TIGR04523  219 QISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEIS 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1119 ENINAVTllREELSEKKSEIASLSKQLSDLGAQLESSISP-SDKAEAISALSKQHEEQELQLQAQLQELSLKVDA---LS 1194
Cdd:TIGR04523  299 DLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEiekLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1195 KEKMSALEQVDHWSNKFSEWKKKAQsrlaQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVR 1274
Cdd:TIGR04523  377 KENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1275 K---SKMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKNYNQQRdtehSGLVQRLQHLEELGEEKDNKVRE 1351
Cdd:TIGR04523  453 EliiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEK 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1352 AEETVLRLREHVSSLEAELGTVKKEL--EHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKiAAIRKQLLSQMEE 1429
Cdd:TIGR04523  529 LESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQK-EKEKKDLIKEIEE 607

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1907199025 1430 KTQryakdtenRLSELSAQLKEREKQVHSLEDKLKNLESS 1469
Cdd:TIGR04523  608 KEK--------KISSLEKELEKAKKENEKLSSIIKNIKSK 639
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 607-1422 1.93e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 56.67  E-value: 1.93e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  607 TEKSLLTKQVVEMETHKKHVceeldaQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQM 686
Cdd:pfam15921   49 TQIPIFPKYEVELDSPRKII------AYPGKEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEM 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  687 REEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLkKELENTVLELSQKEK 766
Cdd:pfam15921  123 QMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVL-QEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  767 QFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGaHQRKLDDVIEAWEKKLSQQAAELRDKHAEQME----EKEQGL 842
Cdd:pfam15921  202 KKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG-RIFPVEDQLEALKSESQNKIELLLQQHQDRIEqlisEHEVEI 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  843 GELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS-LSERESQLQSQVEKLEADLGCSLSEKLS 921
Cdd:pfam15921  281 TGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSeLREAKRMYEDKIEELEKQLVLANSELTE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  922 LQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckSLHELSKKSLEDKSLNLKSLLEELASQLDSR---CERTKALLE 998
Cdd:pfam15921  361 ARTERDQFSQESGNLDDQLQKLLADLHKREKEL----SLEKEQNKRLWDRDTGNSITIDHLRRELDDRnmeVQRLEALLK 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  999 AKTNELVCTSRDKADAILARLSQCQRHTATVGE-----ALLRRMgqVSELEAQLTQLTEEQRT---LKSSFQQVTNQLEE 1070
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEKVSSLTAQlestkEMLRKV--VEELTAKKMTLESSERTvsdLTASLQEKERAIEA 514

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1071 KEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitqLKKELAENINAVTLLREELSEKKSEIASLSKQLSDL-- 1148
Cdd:pfam15921  515 TNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEA----LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMqv 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1149 -GAQLESSISpsdkaeaisalskqheeqelqlqaQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQS 1227
Cdd:pfam15921  591 eKAQLEKEIN------------------------DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLR 646

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1228 TIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVTQRK 1307
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM 726

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1308 KEVESLNETLKNYNQQRDtehsGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSS---V 1384
Cdd:pfam15921  727 KVAMGMQKQITAKRGQID----ALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQerrL 802

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1907199025 1385 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQ 1422
Cdd:pfam15921  803 KEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQ 840
PTZ00121 PTZ00121
MAEBL; Provisional
 749-1479 2.04e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  749 KLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELR 828
Cdd:PTZ00121  1028 KIEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTE 1107

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  829 DKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSlseRESQLQSQVEKL 908
Cdd:PTZ00121  1108 TGKAEEARKAEEAKKKAEDARKAEEARKAE---DARKAEEARKAEDAKRVEIARKAEDARKAEEA---RKAEDAKKAEAA 1181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  909 EADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAE-----KELQSCKSLHELSKKSLEDKSLNLKSLLEELA 983
Cdd:PTZ00121  1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaeavKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  984 SQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTatvgeallRRMGQVSELEAQLTQLTEEQRTLKSSFQQ 1063
Cdd:PTZ00121  1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--------DEAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1064 VTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAvtllrEELSEKKSEIASLSK 1143
Cdd:PTZ00121  1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA-----DEAKKKAEEDKKKAD 1408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1144 QLSDLGAQLESSISPSDKAEAIsalsKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSrlA 1223
Cdd:PTZ00121  1409 ELKKAAAAKKKADEAKKKAEEK----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEE--A 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1224 QHQSTIKDLQAQLDVKATDAREKEEQicllKEDLDRQNKKFECLKGEmEVRKSKMEKKECDLETA---------LKTQTA 1294
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADEAKKAAEA----KKKADEAKKAEEAKKAD-EAKKAEEAKKADEAKKAeekkkadelKKAEEL 1557

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1295 RVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEaelgtVK 1374
Cdd:PTZ00121  1558 KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE-----EK 1632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1375 KELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREK 1454
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEA 1712

                          730       740
                   ....*....|....*....|....*
gi 1907199025 1455 QVHSLEDKLKNLESSPHPEVPAVSR 1479
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKK 1737
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 126-976 2.73e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 2.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  126 DERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKqmttqGEELREQKEKSERAAFEELEKALSTAQKTEDAQR 205
Cdd:pfam02463  153 ERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLE-----ELKLQELKLKEQAKKALEYYQLKEKLELEEEYLL 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  206 RMKMEMDEQmKAVERASEEERLRLQHELS--RVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQE 283
Cdd:pfam02463  228 YLDYLKLNE-ERIDLLQELLRDEQEEIESskQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLE 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  284 QMRIALEKSRSEyLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEH 363
Cdd:pfam02463  307 RRKVDDEEKLKE-SEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  364 LAvhLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQqhQAAVEELREKYQQEKDALLKEKESLfQAHIQ 443
Cdd:pfam02463  386 LS--SAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELE--ILEEEEESIELKQGKLTEEKEELEK-QELKL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  444 DMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRR 523
Cdd:pfam02463  461 LKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  524 AEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQaLAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVL 603
Cdd:pfam02463  541 YKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPK-LKLPLKSIAVLEIDPILNLAQLDKATLEADEDD 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  604 DLETEKSLLTKQVVEMETHKKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENII 683
Cdd:pfam02463  620 KRAKVVEGILKDTELTKLKESAKAKESGLRKGV----SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  684 LQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQ 763
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  764 KEKQFNAQILEMAQ--------ANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQM 835
Cdd:pfam02463  776 LAEEREKTEKLKVEeekeeklkAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  836 EEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCS 915
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  916 LSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLK 976
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELE 996
mukB PRK04863
chromosome partition protein MukB;
285-656 3.92e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 55.73  E-value: 3.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  285 MRIALEKSRSEYLKLTQEKEQQeslaleelelQKKAILTESENKLQELGQEAEAyrtrILELETSLEkslQESKTQSEHL 364
Cdd:PRK04863   275 MRHANERRVHLEEALELRRELY----------TSRRQLAAEQYRLVEMARELAE----LNEAESDLE---QDYQAASDHL 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  365 AVHLEAEK--NKHNK------ELTALAEQHRTEVEGLQQQQDSLWTE---------RLQSLSQQHQAAVEELREK---YQ 424
Cdd:PRK04863   338 NLVQTALRqqEKIERyqadleELEERLEEQNEVVEEADEQQEENEARaeaaeeevdELKSQLADYQQALDVQQTRaiqYQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  425 QEKDALLKEKE-----SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVL--------RGDADKM 491
Cdd:PRK04863   418 QAVQALERAKQlcglpDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVrkiagevsRSEAWDV 497

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  492 KQALEAELEEQRRHHQREVGSISEQQELTVR-----RAEKALKDELSRLGALLDERDE---HLRERQARVQDLE---AHL 560
Cdd:PRK04863   498 ARELLRRLREQRHLAEQLQQLRMRLSELEQRlrqqqRAERLLAEFCKRLGKNLDDEDEleqLQEELEARLESLSesvSEA 577

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  561 QKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDletekSLLTKQvvEMETHKKHVCEELDAQRAQVQQL 640
Cdd:PRK04863   578 RERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGE-----EFEDSQ--DVTEYMQQLLERERELTVERDEL 650

                          410
                   ....*....|....*.
gi 1907199025  641 ERQRSELEEKVRSLAQ 656
Cdd:PRK04863   651 AARKQALDEEIERLSQ 666
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 370-708 5.06e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 55.34  E-value: 5.06e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  370 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwtERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQA----HIQDM 445
Cdd:COG3096    278 NERRELSERALELRRELFGARRQLAEEQYRL--VEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQekieRYQED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  446 NEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaelEEQRR--HHQREVGSISEQQELTVRR 523
Cdd:COG3096    356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD---VQQTRaiQYQQAVQALEKARALCGLP 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  524 --AEKALKDELSRLGALLDERDEHLRERQARVQDLEAH----------LQKSAGE------------------------- 566
Cdd:COG3096    433 dlTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAArrqfekayelVCKIAGEversqawqtarellrryrsqqalaq 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  567 ----LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLER 642
Cdd:COG3096    513 rlqqLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRA 592

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025  643 QRSELEEKVRSLAQLQDS--QLKNSTVEKEQARQSLMEKeniiLQMREEQAKEIEILKQTLSSKEESI 708
Cdd:COG3096    593 RIKELAARAPAWLAAQDAleRLREQSGEALADSQEVTAA----MQQLLEREREATVERDELAARKQAL 656
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
556-784 5.67e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 5.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  556 LEAHLQKSAGELQQALAKLDllhSEQSAAREQAGAYEEQLAQMQQK--VLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 633
Cdd:COG3206    162 LEQNLELRREEARKALEFLE---EQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  634 RAQVQQLERQRSELEEKVRSLAQLQ-----DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESI 708
Cdd:COG3206    239 EARLAALRAQLGSGPDALPELLQSPviqqlRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  709 SILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL--LDQEAKLKKELENTVL------ELSQKEKQFNAQILEMAQANS 780
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELrrLEREVEVARELYESLLqrleeaRLAEALTVGNVRVIDPAVVPL 398


                   ....
gi 1907199025  781 AGIS 784
Cdd:COG3206    399 KPVS 402
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 550-771 6.41e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.00  E-value: 6.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  550 QARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEE 629
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  630 LDAQRAQVQQLER--QRSELEEKVRSLAQLQDSQ--LKNSTVEKE--QARQSLMEKENIILQMREEQAKEIEILKQTLSS 703
Cdd:COG4942     99 LEAQKEELAELLRalYRLGRQPPLALLLSPEDFLdaVRRLQYLKYlaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025  704 KEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQ 771
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 116-840 7.98e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.59  E-value: 7.98e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  116 SEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEKALS 195
Cdd:pfam02463  271 LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIK 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  196 TAQKTEDAQRRMKmEMDEQMKAVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELAS-----KEQEL 270
Cdd:pfam02463  351 REAEEEEEEELEK-LQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDllkeeKKEEL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  271 SRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSL 350
Cdd:pfam02463  430 EILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  351 EKSLQESKTQ-----------SEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEEL 419
Cdd:pfam02463  510 KVLLALIKDGvggriisahgrLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  420 REK-YQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAE 498
Cdd:pfam02463  590 PLKsIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  499 LEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLH 578
Cdd:pfam02463  670 ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  579 SEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQ 658
Cdd:pfam02463  750 EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE----EELKEEAELLEEEQLLIE 825

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  659 DSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQE 738
Cdd:pfam02463  826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEE 905

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  739 TKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEK 818
Cdd:pfam02463  906 SQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEE 985

                          730       740
                   ....*....|....*....|..
gi 1907199025  819 KLSQQAAELRDKHAEQMEEKEQ 840
Cdd:pfam02463  986 KEERYNKDELEKERLEEEKKKL 1007
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1322-1906 8.64e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 8.64e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1322 QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLElE 1401
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA-R 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1402 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTEnRLSELSAQLKEREKQVHSLEDKLKNLESSphpevpavsRSM 1481
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEE-ELEELEEELEEAEEELEEAEAELAEAEEA---------LLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1482 QSVAASPEQEApdsqdctHKACKERLCMLQRRLSEKEKLLRRLEQGEGEARpsqpEAQHRALSGKLDCTRARQLEDHVLI 1561
Cdd:COG1196    370 AEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALL----ERLERLEEELEELEEALAELEEEEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1562 GCLPEELEEKmkcslivsqpmGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEK 1641
Cdd:COG1196    439 EEEEALEEAA-----------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFL 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1642 LTLKYEKSQSSQQEMDGEnkcVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK-------LSKEVARL 1714
Cdd:COG1196    508 EGVKAALLLAGLRGLAGA---VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIRA 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1715 QKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAE 1794
Cdd:COG1196    585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1795 LLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTILELQT 1874
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1907199025 1875 QLAQKTTLISD--SKLKEQELREQVHNLEDRLKR 1906
Cdd:COG1196    745 EELLEEEALEElpEPPDLEELERELERLEREIEA 778
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
144-679 9.81e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.15  E-value: 9.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  144 KRQMLETLELKEDeIAQLRSHIKQ---MTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAV 218
Cdd:COG4913    214 REYMLEEPDTFEA-ADALVEHFDDlerAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLEL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  219 ERAsEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALE-KSRSEYL 297
Cdd:COG4913    293 LEA-ELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARlEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  298 KLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKnkhnK 377
Cdd:COG4913    372 GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR----D 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  378 ELTALAEQHRTEV----EGLQ-QQQDSLWT---ERL---QSLS----QQHQAAVeelREKYQQEKDAL----LKEKESLF 438
Cdd:COG4913    448 ALAEALGLDEAELpfvgELIEvRPEEERWRgaiERVlggFALTllvpPEHYAAA---LRWVNRLHLRGrlvyERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  439 QAHIQDMNEKTL-EKLDKK--------QMELESVSS--------ELSEALRA------------------RDQLAEELsV 483
Cdd:COG4913    525 DPERPRLDPDSLaGKLDFKphpfrawlEAELGRRFDyvcvdspeELRRHPRAitragqvkgngtrhekddRRRIRSRY-V 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  484 LRGDADKMKQALEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDELSRLGALLDerdehLRERQARVQDLEAHLQks 563
Cdd:COG4913    604 LGFDNRAKLAALEAELAELEEELAE-----AEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAEREIA-- 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  564 agELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDA-----QRAQVQ 638
Cdd:COG4913    672 --ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaedlaRLELRA 749

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907199025  639 QLERQRSEL--EEKVRSLAQLQDSQLKNSTVEKEQARQSLMEK 679
Cdd:COG4913    750 LLEERFAAAlgDAVERELRENLEERIDALRARLNRAEEELERA 792
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 237-848 1.02e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 54.07  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  237 RQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEA-----RERELQEQMRIALEKSRSEYLKLTQEKEQQESLAL 311
Cdd:pfam12128  277 RQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvakdrSELEALEDQHGAFLDADIETAAADQEQLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  312 EELELQKKAiLTESENKLQElgqeaeAYRTRILELetslekslqesktqSEHLAVHLEAEKNKHNKELTALAEQHrTEVE 391
Cdd:pfam12128  357 ENLEERLKA-LTGKHQDVTA------KYNRRRSKI--------------KEQNNRDIAGIKDKLAKIREARDRQL-AVAE 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  392 GLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEK----DALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL 467
Cdd:pfam12128  415 DDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKlrlnQATATPELLLQLENFDERIERAREEQEAANAEVERLQSEL 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  468 SEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLR 547
Cdd:pfam12128  495 RQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSV 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  548 ERQARVQDLEAHLQK-----SAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL----------- 611
Cdd:pfam12128  575 GGELNLYGVKLDLKRidvpeWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFartalknarld 654

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  612 LTKQVVEMETHKKHVCEELDAQRA----QVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLM-EKENIILQM 686
Cdd:pfam12128  655 LRRLFDEKQSEKDKKNKALAERKDsaneRLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEgALDAQLALL 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  687 REEQAKEIEILKQTLSS--------------KEESISILH---EEYETKFKNQEKRMEKIKQKAKEMQETkkkLLDQEAK 749
Cdd:pfam12128  735 KAAIAARRSGAKAELKAletwykrdlaslgvDPDVIAKLKreiRTLERKIERIAVRRQEVLRYFDWYQET---WLQRRPR 811

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  750 LKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEENQRQQIESLTG--AHQRKLDDVIEAWEKKLSQQAAEL 827
Cdd:pfam12128  812 LATQLSNIERAISELQQQLARLIADTKLRRAK-LEMERKASEKQQVRLSENLRGlrCEMSKLATLKEDANSEQAQGSIGE 890

                          650       660
                   ....*....|....*....|.
gi 1907199025  828 RDKHAEQMEEKEQGLGELRQK 848
Cdd:pfam12128  891 RLAQLEDLKLKRDYLSESVKK 911
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 101-435 1.22e-06

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 53.59  E-value: 1.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  101 KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmletlelkedeiAQLRSHIKQMTTQGEELREQKE 180
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQ------------AEMDRQAAIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  181 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKaVERASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA 260
Cdd:pfam17380  349 ELERIRQEERKRELERIRQEEIAMEISRMRELERLQ-MERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  261 EELASKEQELSRRLEARERELqEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKlQELGQEAEAYR 340
Cdd:pfam17380  428 EQEEARQREVRRLEEERAREM-ERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRR-KILEKELEERK 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  341 TRILELETslEKSLQESKTQSEHLAVHLEAEKNKHNKELTalAEQHRTEVEGLQQQQDSLWTERlqslsqQHQAAVEELR 420
Cdd:pfam17380  506 QAMIEEER--KRKLLEKEMEERQKAIYEEERRREAEEERR--KQQEMEERRRIQEQMRKATEER------SRLEAMERER 575

                          330
                   ....*....|....*
gi 1907199025  421 EKYQQEKDALLKEKE 435
Cdd:pfam17380  576 EMMRQIVESEKARAE 590
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
87-639 1.27e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.77  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   87 QQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQmLETLELKEDEIAQLRSHIK 166
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLERE-IERLERELEERERRRARLE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  167 QMTTQGEElreqKEKSERAAFEEL-EKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERlRLQHELSRVRQeaasmAK 245
Cdd:COG4913    366 ALLAALGL----PLPASAEEFAALrAEAAALLEALEEELEALEEALAEAEAALRDLRRELR-ELEAEIASLER-----RK 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  246 KNSEEQVAALQKLHAEELASKEQELS--------RRLEAR-----EREL----------QEQMRIALEKSRSEYLK--LT 300
Cdd:COG4913    436 SNIPARLLALRDALAEALGLDEAELPfvgelievRPEEERwrgaiERVLggfaltllvpPEHYAAALRWVNRLHLRgrLV 515

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  301 QEKEQQESLALEELELQKKAILteseNKLQELGQEAEAYRTRILELETSLEK--SLQESKT---------QSEHLAVHLE 369
Cdd:COG4913    516 YERVRTGLPDPERPRLDPDSLA----GKLDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRhpraitragQVKGNGTRHE 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  370 AEKNKHNKELTALAEQHRTEVEGLQQQQDSLwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLF--------QAH 441
Cdd:COG4913    592 KDDRRRIRSRYVLGFDNRAKLAALEAELAEL-EEELAEAEER-LEALEAELDALQERREALQRLAEYSWdeidvasaERE 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  442 IQDmNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTV 521
Cdd:COG4913    670 IAE-LEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  522 RRAEKALKDelsrlgALLDERDEHLRER-QARVQDLEAHLQKSAGELQQALAKL----DLLHSEQSAAREQAGAYEEQLA 596
Cdd:COG4913    749 ALLEERFAA------ALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFnrewPAETADLDADLESLPEYLALLD 822

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1907199025  597 QMQQKVL-DLETE-KSLLTKQvveMETHKKHVCEELDAQRAQVQQ 639
Cdd:COG4913    823 RLEEDGLpEYEERfKELLNEN---SIEFVADLLSKLRRAIREIKE 864
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 109-777 1.72e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.72e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  109 EQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAafE 188
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQ--L 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  189 ELEKALSTAQKTEDAQRRMKMEMDEQMKAVERASEEERL------------RLQHELSRVRQEAASMAKKNSEEQVAALQ 256
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLaahikavtqieqQAQRIHTELQSKMRSRAKLLMKRAAHVKQ 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  257 KLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLK---LTQEKEQQESLALEELELQKKAILTESENKLQELG 333
Cdd:TIGR00618  337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhiHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRT 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  334 QEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKhNKELTALAEQHRTEVEGLQQQQDSLwterlqsLSQQHQ 413
Cdd:TIGR00618  417 SAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLE-KIHLQESAQSLKEREQQLQTKEQIH-------LQETRK 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  414 AAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlRARDQLAEELSVLRGDADKMKQ 493
Cdd:TIGR00618  489 KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE-DVYHQLTSERKQRASLKEQMQE 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  494 ALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAK 573
Cdd:TIGR00618  568 IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  574 L-----DLLHSEQSAAREQAGAYEEQLAQMQQKVLD---------------LETEKSLLTKQVVEMETHKKHVCEELDAQ 633
Cdd:TIGR00618  648 LhalqlTLTQERVREHALSIRVLPKELLASRQLALQkmqsekeqltywkemLAQCQTLLRELETHIEEYDREFNEIENAS 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  634 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiILQMREEQAKEIEILKQTLSSKEESISILHE 713
Cdd:TIGR00618  728 SSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199025  714 EYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQ 777
Cdd:TIGR00618  807 EIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
PTZ00121 PTZ00121
MAEBL; Provisional
 641-1263 1.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 1.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  641 ERQRSELEEKVRSLAQLQDSQLKnstveKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEEsisilheeyetKFK 720
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKD-----AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE-----------ARK 1279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  721 NQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQilemaqansagiSDTVSRLEENQRQQIES 800
Cdd:PTZ00121  1280 ADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKK------------ADAAKKKAEEAKKAAEA 1347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  801 LTGAHQRKLDDVIEAWEKKlsqQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGL 880
Cdd:PTZ00121  1348 AKAEAEAAADEAEAAEEKA---EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  881 QGQLEQKSAVIVSLSERESQLQSQV-----EKLEADLGCSLSEKLSLQEEL---AELKLLADKSQLRVSELTGQVQAAEK 952
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKAEEAKKADEAkkkaeEAKKAEEAKKKAEEAKKADEAkkkAEEAKKADEAKKKAEEAKKKADEAKK 1504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  953 ELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTATVGEA 1032
Cdd:PTZ00121  1505 AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1033 LLRRMGQVSELEaqLTQLTEEQRTLKSsfQQVTNQLEEKEKQIKTMKAdieglltekEALQQEGGQQRQAASEKESCITQ 1112
Cdd:PTZ00121  1585 EAKKAEEARIEE--VMKLYEEEKKMKA--EEAKKAEEAKIKAEELKKA---------EEEKKKVEQLKKKEAEEKKKAEE 1651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1113 LKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQheeqelqlqaqLQELSLKVDA 1192
Cdd:PTZ00121  1652 LKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKK-----------EAEEKKKAEE 1720

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025 1193 LSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1263
Cdd:PTZ00121  1721 LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEK 1791
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 436-660 3.97e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 3.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  436 SLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALeAELEEQRRHHQREVGSISE 515
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRI-RALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  516 QQElTVRRAEKALKDELSRLGALLderdehlrERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQL 595
Cdd:COG4942     91 EIA-ELRAELEAQKEELAELLRAL--------YRLGRQPPLALLL--SPEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  596 AQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS 660
Cdd:COG4942    160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 91-647 4.03e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.37  E-value: 4.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   91 KRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTT 170
Cdd:TIGR02168  392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  171 QGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQM--------------------KAVERASEEerlRLQ 230
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgilgvlselisvdegyeAAIEAALGG---RLQ 548

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  231 HELSR----VRQEAASMAKKN---------SEEQVAALQKLHAEELASKEQELSRRLEARERELQ--------------- 282
Cdd:TIGR02168  549 AVVVEnlnaAKKAIAFLKQNElgrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvv 628

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  283 EQMRIALE---KSRSEYLKLTQEKEQQESL-ALEELELQKKAILTESENKLQELGQEAEAYRTRILELETSLE--KSLQE 356
Cdd:TIGR02168  629 DDLDNALElakKLRPGYRIVTLDGDLVRPGgVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAelRKELE 708

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  357 SKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQslSQQHQAAVEELREKYQQEKDALLKEKES 436
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE--LEAEIEELEERLEEAEEELAEAEAEIEE 786

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  437 LfQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQ 516
Cdd:TIGR02168  787 L-EAQIEQLKEE-LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  517 QEltvrrAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLA 596
Cdd:TIGR02168  865 EE-----LIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  597 QMQQKVldleTEKSLLTKQvvEMETHKKHVCEELDAQRAQVQQLERQRSEL 647
Cdd:TIGR02168  940 NLQERL----SEEYSLTLE--EAEALENKIEDDEEEARRRLKRLENKIKEL 984
PRK11281 PRK11281
mechanosensitive channel MscK;
513-863 4.15e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.22  E-value: 4.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  513 ISEQQELTVrrAEKALKDELSRLGALLDERDEHlrerQARVQDLEAHLQKSAGELQQALAKLDLL-HSEQSAAREQAGAY 591
Cdd:PRK11281    48 LNKQKLLEA--EDKLVQQDLEQTLALLDKIDRQ----KEETEQLKQQLAQAPAKLRQAQAELEALkDDNDEETRETLSTL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  592 -----EEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSEL---------EEKVRSLAQL 657
Cdd:PRK11281   122 slrqlESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGkvggkalrpSQRVLLQAEQ 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  658 QDSQLKNstvekEQARQSLmeKENIILQM-----REEQAKEIEILKQTLSSKEESISilheeyetkfknqEKRMEKIKQK 732
Cdd:PRK11281   202 ALLNAQN-----DLQRKSL--EGNTQLQDllqkqRDYLTARIQRLEHQLQLLQEAIN-------------SKRLTLSEKT 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  733 AKEMQETKKK-------LLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQansagISDTVSRLEENQRQQIESLTGA- 804
Cdd:PRK11281   262 VQEAQSQDEAariqanpLVAQELEINLQLSQRLLKATEKLNTLTQQNLRVKN-----WLDRLTQSERNIKEQISVLKGSl 336

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  805 --------HQRKL--DDVIeaweKKLSQQAAELRDKHAEQMEEKEQgLGELRQKV-RIVQSEKEELTKEV 863
Cdd:PRK11281   337 llsrilyqQQQALpsADLI----EGLADRIADLRLEQFEINQQRDA-LFQPDAYIdKLEAGHKSEVTDEV 401
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 326-675 4.41e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 52.26  E-value: 4.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  326 ENKLQELGQEAEAYRTRILELETSLEK--SLQESKTQ--SEHLAVHLEAEKnkhnKELTALAEQHRTEVEGLQQQQdslw 401
Cdd:COG3096    784 EKRLEELRAERDELAEQYAKASFDVQKlqRLHQAFSQfvGGHLAVAFAPDP----EAELAALRQRRSELERELAQH---- 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  402 terlQSLSQQHQAAVEELREKyQQEKDALLKEKESLFQAHIQDMnektLEKLDKKQMELESVSSELSEALRARDQLAEEL 481
Cdd:COG3096    856 ----RAQEQQLRQQLDQLKEQ-LQLLNKLLPQANLLADETLADR----LEELREELDAAQEAQAFIQQHGKALAQLEPLV 926

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  482 SVLRGDA---DKMKQALEAELEEQRRHHQRevgsISEQQELTVRRAEKALKDELSRLGALlDERDEHLRER-----QARV 553
Cdd:COG3096    927 AVLQSDPeqfEQLQADYLQAKEQQRRLKQQ----IFALSEVVQRRPHFSYEDAVGLLGEN-SDLNEKLRARleqaeEARR 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  554 QDLEAhLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSlltkqvvemETHKKHVCEELDAQ 633
Cdd:COG3096   1002 EAREQ-LRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAEERA---------RIRRDELHEELSQN 1071

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1907199025  634 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 675
Cdd:COG3096   1072 RSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQA 1113
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 527-753 5.20e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  527 ALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLE 606
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  607 TE----KSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDsQLKNSTVEKEQARQSLMEKENI 682
Cdd:COG4942     97 AEleaqKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE-ELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  683 ILQMREEQAKEIEILKQTLSSKEESISILheeyETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKE 753
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARL----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1051-1263 5.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1051 TEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREE 1130
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1131 LSEKKSEIASLSKQLSDLGAQ--LESSISPSDKAEAISALS---------KQHEEQELQLQAQLQELSLKVDALSKEKMS 1199
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQylkylaparREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199025 1200 ALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKK 1263
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 318-1434 6.01e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.98  E-value: 6.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  318 KKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQES---KTQSEHL---------------AVHLE--------AE 371
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSihlEKEIKDLfdkyleiddeiiyinKLKLElkekikniSD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  372 KNKHNK---ELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQ--------- 439
Cdd:TIGR01612  615 KNEYIKkaiDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKenaidnted 694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  440 -AHIQDMNEKTLEKLDKKQ-MELESVSSELSEALRARDQLAEELSvlrgdadKMKQALEAELeeqrrhhQREVGSISEQq 517
Cdd:TIGR01612  695 kAKLDDLKSKIDKEYDKIQnMETATVELHLSNIENKKNELLDIIV-------EIKKHIHGEI-------NKDLNKILED- 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  518 eltVRRAEKALKdelSRLGALLDERDEhLRERQARVQDLEAHL--QKSAGELQQALAKLDLLHSEQSAarEQAGAYEEQL 595
Cdd:TIGR01612  760 ---FKNKEKELS---NKINDYAKEKDE-LNKYKSKISEIKNHYndQINIDNIKDEDAKQNYDKSKEYI--KTISIKEDEI 830

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  596 AQMQQKVLDLETEKSLLTKQVVEMETHKKhvcEELDAQRAQVQQL---------ERQRSELEEKVRSLAQLQDSqlKNST 666
Cdd:TIGR01612  831 FKIINEMKFMKDDFLNKVDKFINFENNCK---EKIDSEHEQFAELtnkikaeisDDKLNDYEKKFNDSKSLINE--INKS 905

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  667 VEKEQARQSLMEKENIILQM-----------REEQAKEIEILKQTLSSKEESISIlHEEYETKFKN----QEKRMEKIKQ 731
Cdd:TIGR01612  906 IEEEYQNINTLKKVDEYIKIcentkesiekfHNKQNILKEILNKNIDTIKESNLI-EKSYKDKFDNtlidKINELDKAFK 984

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  732 KAK------EMQETKKKLLDQEAKLKKELENTVL-ELSQKEKQFNAQILEMAQANS----------AGISDTVSRLEENQ 794
Cdd:TIGR01612  985 DASlndyeaKNNELIKYFNDLKANLGKNKENMLYhQFDEKEKATNDIEQKIEDANKnipnieiaihTSIYNIIDEIEKEI 1064

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  795 RQQIESLTGAHQRKLDDVIEAWEK--------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKE---- 862
Cdd:TIGR01612 1065 GKNIELLNKEILEEAEINITNFNEikeklkhyNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKseny 1144

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  863 VARLKEAVSG-QDVALAGLQGQ----LEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE----------ELA 927
Cdd:TIGR01612 1145 IDEIKAQINDlEDVADKAISNDdpeeIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEvkginlsygkNLG 1224

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  928 ELKLLADKSQLRVSELTgqVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCT 1007
Cdd:TIGR01612 1225 KLFLEKIDEEKKKSEHM--IKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISD 1302

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1008 SRDKADAIL-----------------ARLSQCQRHTATVGEAL-----LRRMGQVSELEAQLTQLTEEQRTLKSSFQQVT 1065
Cdd:TIGR01612 1303 IREKSLKIIedfseesdindikkelqKNLLDAQKHNSDINLYLneianIYNILKLNKIKKIIDEVKEYTKEIEENNKNIK 1382

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1066 NQLEEKEKQIKTMKAD---------IEGLLTEK---EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLRE-ELS 1132
Cdd:TIGR01612 1383 DELDKSEKLIKKIKDDinleeckskIESTLDDKdidECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNiEMA 1462

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1133 EKKSE-IASLSKQ--LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKeKMSALEqvdhWSN 1209
Cdd:TIGR01612 1463 DNKSQhILKIKKDnaTNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLN-KYSALA----IKN 1537

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1210 KFSEWKKKAQSRLAQhqstIKDLQAQLDVKATDAREKEEQIcllkedldrqnkKFECLKGEMEVRKS-KMEKKECDLETA 1288
Cdd:TIGR01612 1538 KFAKTKKDSEIIIKE----IKDAHKKFILEAEKSEQKIKEI------------KKEKFRIEDDAAKNdKSNKAAIDIQLS 1601

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1289 LKTQTARVVELEDCVTQRK---KEVESLNETLKNYN-QQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETvlrlrehvs 1364
Cdd:TIGR01612 1602 LENFENKFLKISDIKKKINdclKETESIEKKISSFSiDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK--------- 1672

                         1210      1220      1230      1240      1250      1260      1270
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025 1365 sleaelgtvKKELEHVNSSVKSRDGELKALEDKLELESAAKV-ELKRKAEQKIAAIRKQLLSQMEEKTQRY 1434
Cdd:TIGR01612 1673 ---------KKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIkEIAIANKEEIESIKELIEPTIENLISSF 1734
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 939-1467 7.39e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.09  E-value: 7.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  939 RVSELTGQVQAAEK--ELQSCKSLHELSKKSLEDKSLNLK-SLLEELASQLDSRCERTKALLEAKTNEL------VCTSR 1009
Cdd:COG1196    201 QLEPLERQAEKAERyrELKEELKELEAELLLLKLRELEAElEELEAELEELEAELEELEAELAELEAELeelrleLEELE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1010 DKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKssfqqvtNQLEEKEKQIKTMKADIEGLLTEK 1089
Cdd:COG1196    281 LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELE-------EELEELEEELEELEEELEEAEEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1090 EALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISpsdKAEAISALS 1169
Cdd:COG1196    354 EEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE---ELEELEEAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1170 KQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQStiKDLQAQLDVKATDAREKEEQ 1249
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1250 ICLLKEDLDRQNKKFECLKGEMEVRKSkmekkecdLETALktQTARVVELEDCVTQRKKEVESLNETLKNYNQQRDT--- 1326
Cdd:COG1196    509 GVKAALLLAGLRGLAGAVAVLIGVEAA--------YEAAL--EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflp 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1327 ----EHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSVKSRDGEL-KALEDKLELE 1401
Cdd:COG1196    579 ldkiRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLReVTLEGEGGSA 658

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199025 1402 SAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 81-447 7.41e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 51.21  E-value: 7.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDEIAQ 160
Cdd:TIGR02168  719 KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE------------EELAEAEAEIEE 786

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  161 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEDAQRRMkmemdeqmkaverASEEERLRLQHELSRVRQEA 240
Cdd:TIGR02168  787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI-------------AATERRLEDLEEQIEELSED 853

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  241 ASMAKKNSEEQVAALQKLHAE-ELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEqqeslaleelelQKK 319
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESElEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE------------ELR 921

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  320 AILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQds 399
Cdd:TIGR02168  922 EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELK-- 999

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025  400 lwtERLQSLSQQHqAAVEELREKYQQEKDALLKEKESLFQAHIQDMNE 447
Cdd:TIGR02168 1000 ---ERYDFLTAQK-EDLTEAKETLEEAIEEIDREARERFKDTFDQVNE 1043
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
81-649 8.03e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 8.03e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRC---KETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKgmvitetkrqmlETLELKEDE 157
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYeeqREQARETRDEADEVLEEHEERREELETLEAEIEDLR------------ETIAETERE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  158 IAQLRSHIKQMTTQGEELREqkEKSERAAFEELEKAlstAQKTEDAQRRmkmEMDEQMKAVERASEEERLRLqhelsrvr 237
Cdd:PRK02224   274 REELAEEVRDLRERLEELEE--ERDDLLAEAGLDDA---DAEAVEARRE---ELEDRDEELRDRLEECRVAA-------- 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  238 QEAASMAKKNSEEqvaalqklhAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEELELq 317
Cdd:PRK02224   338 QAHNEEAESLRED---------ADDLEERAEELREEAAELESELEEA-REAVEDRREEIEELEEEIEELRERFGDAPVD- 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  318 kkaiLTESENKLQELGQEAEAYRTRILELETSLeKSLQESKTQSEHL---------------AVHLEA--EKNKHNKELT 380
Cdd:PRK02224   407 ----LGNAEDFLEELREERDELREREAELEATL-RTARERVEEAEALleagkcpecgqpvegSPHVETieEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  381 ALAEQHRTEVEGLQQQqdslwTERLQSLSQQhQAAVEELREKYQQEKDALLKEKESLfqahiqDMNEKTLEKLDKKQMEL 460
Cdd:PRK02224   482 AELEDLEEEVEEVEER-----LERAEDLVEA-EDRIERLEERREDLEELIAERRETI------EEKRERAEELRERAAEL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  461 ESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRhhqrevgsISEQQEL--TVRRAEKALKDELSRLGAL 538
Cdd:PRK02224   550 EAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLER--------IRTLLAAiaDAEDEIERLREKREALAEL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  539 LDERDEHLRERQARVQDLEAHLQKSAGElqqalakldllhseqsAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQV-- 616
Cdd:PRK02224   622 NDERRERLAEKRERKRELEAEFDEARIE----------------EAREDKERAEEYLEQVEEKLDELREERDDLQAEIga 685

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1907199025  617 VEMETHK-KHVCEELDAQRAQVQQLERQRSELEE 649
Cdd:PRK02224   686 VENELEElEELRERREALENRVEALEALYDEAEE 719
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1668-1910 8.52e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 8.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1668 DRPEENSQSHEIQSNVGTVDGLRSDLESkltgaERDKQKLSKEVARLQKELRALRRE---HQQELDILKRECEQEAEEKL 1744
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERlaeLEYLRAALRLWFAQRRLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1745 KQEQEDLELKHTstlkqlmrefntQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRY 1824
Cdd:COG4913    294 EAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1825 EEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDsvtilELQTQLAqkttlisDSKLKEQELREQVHNLEDRL 1904
Cdd:COG4913    362 AR-LEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE-----ALEEALA-------EAEAALRDLRRELRELEAEI 428


                   ....*.
gi 1907199025 1905 KRYEKN 1910
Cdd:COG4913    429 ASLERR 434
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1667-1910 9.38e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.83  E-value: 9.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1667 EDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQK------LSKEVARLQKELRALR-REHQQELDILKREcEQE 1739
Cdd:TIGR02168  172 ERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKaerykeLKAELRELELALLVLRlEELREELEELQEE-LKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1740 AEEKLKQEQEDLELKHTStLKQLMREFNtQLAQKEQELERTVQETIDKAQEVEAElLESHQEETQQLHRKIAEKEDDLRR 1819
Cdd:TIGR02168  251 AEEELEELTAELQELEEK-LEELRLEVS-ELEEEIEELQKELYALANEISRLEQQ-KQILRERLANLERQLEELEAQLEE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1820 TARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSVTilELQTQLAQKTTLISDSKLKEQELREQVHN 1899
Cdd:TIGR02168  328 LESKLDE-LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE--ELEEQLETLRSKVAQLELQIASLNNEIER 404

                          250
                   ....*....|.
gi 1907199025 1900 LEDRLKRYEKN 1910
Cdd:TIGR02168  405 LEARLERLEDR 415
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
156-739 1.10e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  156 DEIAQLRSHIKQMTTQGEELREQKEKSeRAAFEELEKALSTAQKTEDAQRRMKMEMDEQMKAVErASEEERLRLQHELSR 235
Cdd:PRK02224   206 ERLNGLESELAELDEEIERYEEQREQA-RETRDEADEVLEEHEERREELETLEAEIEDLRETIA-ETEREREELAEEVRD 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  236 VRQEAASMAKKNSEEQV-AALQKLHAEELASKEQELSRRLEARERELQEQmRIALEKSRSEYLKLTQEKEqqeslaleel 314
Cdd:PRK02224   284 LRERLEELEEERDDLLAeAGLDDADAEAVEARREELEDRDEELRDRLEEC-RVAAQAHNEEAESLREDAD---------- 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  315 elqkkailtesenklqELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAvhleaeknkhnkELTALAEQHRTEVEGLQ 394
Cdd:PRK02224   353 ----------------DLEERAEELREEAAELESELEEAREAVEDRREEIE------------ELEEEIEELRERFGDAP 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  395 QQQDSLwTERLQSLSQQHQAAVE---ELREKYQQEKDALlKEKESLFQAHIQDMNEKTLEkldkkqmelesvSSELSEAL 471
Cdd:PRK02224   405 VDLGNA-EDFLEELREERDELREreaELEATLRTARERV-EEAEALLEAGKCPECGQPVE------------GSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  472 RARDQLAEELSVLRGDADKMKQALEAELEEqrrhhqrevgsiSEQQELTVRRAEKaLKDELSRLGALLDERDEHLRERQA 551
Cdd:PRK02224   471 EEDRERVEELEAELEDLEEEVEEVEERLER------------AEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRE 537

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  552 RVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLtkqvvEMETHKKHVCEELD 631
Cdd:PRK02224   538 RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL-----AAIADAEDEIERLR 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  632 AQRAQVQQLERQR----SELEEKVRSL-AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKeieiLKQTLSSKEE 706
Cdd:PRK02224   613 EKREALAELNDERrerlAEKRERKRELeAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDD----LQAEIGAVEN 688

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1907199025  707 SISILHE--EYETKFKNQEKRMEKIKQKAKEMQET 739
Cdd:PRK02224   689 ELEELEElrERREALENRVEALEALYDEAEELESM 723
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 515-1079 1.24e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  515 EQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSeqsaareqagayeeQ 594
Cdd:TIGR04523  130 EKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKN--------------K 195

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  595 LAQMQQKVLDLETEKS---LLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTVE 668
Cdd:TIGR04523  196 LLKLELLLSNLKKKIQknkSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikKQLSEKQKE 275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  669 KEQARQSLMEKENIILQMReeqaKEIEILKQtlsskeESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEA 748
Cdd:TIGR04523  276 LEQNNKKIKELEKQLNQLK----SEISDLNN------QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  749 KLKKELENTVLELSQKEKQfnaqilemaqansagisdtvsrLEENQrQQIESLTGAHQRKLDDVieaweKKLSQQAAELR 828
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRE----------------------LEEKQ-NEIEKLKKENQSYKQEI-----KNLESQINDLE 397

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  829 DKHAEQMEEKEQglgeLRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKL 908
Cdd:TIGR04523  398 SKIQNQEKLNQQ----KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVL 473

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  909 EADLGCSLSEKLSLQEELAE-----LKLLADKSQL--RVSELTGQVQAA---EKELQSCKSLHELSKKSLEDKSLNLKSL 978
Cdd:TIGR04523  474 SRSINKIKQNLEQKQKELKSkekelKKLNEEKKELeeKVKDLTKKISSLkekIEKLESEKKEKESKISDLEDELNKDDFE 553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  979 L--EELASQLDSRCERTKALLEAKTNELVctSRDKADAILARLSQCQRhtaTVGEALLRRMGQVSELEAQLTQLTEEQRT 1056
Cdd:TIGR04523  554 LkkENLEKEIDEKNKEIEELKQTQKSLKK--KQEEKQELIDQKEKEKK---DLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          570       580
                   ....*....|....*....|...
gi 1907199025 1057 LKSSFQQVTNQLEEKEKQIKTMK 1079
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIK 651
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 588-826 1.99e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 1.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  588 AGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSL-AQLQDSQLKNST 666
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALeAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  667 VEKEQARQSLMEKENIILQMREEQAKEIEILkqtLSSKEESISILHEEYETKF-KNQEKRMEKIKQKAKEMQETKKKLLD 745
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  746 QEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgisdtvsrlEENQRQQIESLTGAhQRKLDDVIEAWEKKLSQQAA 825
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKE---------LAELAAELAELQQE-AEELEALIARLEAEAAAAAE 241


                   .
gi 1907199025  826 E 826
Cdd:COG4942    242 R 242
PTZ00121 PTZ00121
MAEBL; Provisional
 290-998 1.99e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.99e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  290 EKSRSEYLKLTQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRtRILELETSLEKSLQESKTQSEHLAVHLE 369
Cdd:PTZ00121  1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR-KAEEARKAEDAKRVEIARKAEDARKAEE 1168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  370 AEKNKHNKELTAL--AEQHRTEVEgLQQQQDSLWTERLQSLSQQHQAavEELReKYQQEKDAllkekESLFQAHIQDMNE 447
Cdd:PTZ00121  1169 ARKAEDAKKAEAArkAEEVRKAEE-LRKAEDARKAEAARKAEEERKA--EEAR-KAEDAKKA-----EAVKKAEEAKKDA 1239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  448 KTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQrevgSISEQQELTVRRAEKA 527
Cdd:PTZ00121  1240 EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAE----EKKKADEAKKKAEEAK 1315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  528 LKDELSRLGALLDERDEHLRERqarvqdleAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLET 607
Cdd:PTZ00121  1316 KADEAKKKAEEAKKKADAAKKK--------AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  608 EKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENiiLQMR 687
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE--AKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  688 EEQAKEIEILKQTLSSKEESISILHEEYETKFKNQE-KRMEKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEK 766
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEaKKAAEAKKKADEAKKAEEAKKADEAK-KAEEAKKADEAKKAEE 1544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  767 QFNAQilEMAQANSAGISDTVSRLEENQRQQ---------IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEE 837
Cdd:PTZ00121  1545 KKKAD--ELKKAEELKKAEEKKKAEEAKKAEedknmalrkAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  838 KE-QGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQ--KSAVIVSLSERESQLQSQVEKLEADLGC 914
Cdd:PTZ00121  1623 EElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  915 SLSEklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTK 994
Cdd:PTZ00121  1703 KAEE---LKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779


                   ....
gi 1907199025  995 ALLE 998
Cdd:PTZ00121  1780 VIEE 1783
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 1937-1976 2.00e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 43.50  E-value: 2.00e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 1907199025 1937 TEFEYLRKVMFEYMMGRET---KTMAKVITTVLKFPDDQAQKI 1976
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1069-1864 2.14e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.97  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1069 EEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAAS----EKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQ 1144
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKlkeqAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1145 LSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQ 1224
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1225 HQSTIKDLQAQLDVKATDAREKEEQICLLKEdldrQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELEDCVT 1304
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEE----EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1305 QRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELGTVKKELEHVNSSV 1384
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1385 KSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLK 1464
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1465 NLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCT--HKACKERLCMLQRRLSEKEKLLRRLEQGEGEARPSQPEAQHRA 1542
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1543 LSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQKTLQEKELTCQALEQRVK 1622
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1623 ELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAER 1702
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1703 DKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQELERTVQ 1782
Cdd:pfam02463  802 ELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1783 ETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 1862
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER 961


                   ..
gi 1907199025 1863 TK 1864
Cdd:pfam02463  962 NK 963
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
248-858 2.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  248 SEEQVAALQKLHAEELASKEQELSRrLEARERELQEQmriaLEKSRSEYLKLTQEKEQQESLALEELELQKKaiLTESEN 327
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINE-ISSELPELREE----LEKLEKEVKELEELKEEIEELEKELESLEGS--KRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  328 KLQELGQEAEAYRTRILELETSLE--KSLQESKTQSEHLaVHLEAEKNKHNKELTALAEQHRTEVEGLQqqqdslwtERL 405
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKelKELKEKAEEYIKL-SEFYEEYLDELREIEKRLSRLEEEINGIE--------ERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  406 QSLSQQhQAAVEELREKYQ--QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSV 483
Cdd:PRK03918   331 KELEEK-EERLEELKKKLKelEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  484 LRGDADKMKQaleaeleeqrrhhqrevgsISEQQELTVRRAEKAlKDELSRLGALLDE--RDEHLRERQARVQDLEAHLQ 561
Cdd:PRK03918   410 ITARIGELKK-------------------EIKELKKAIEELKKA-KGKCPVCGRELTEehRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  562 KSAGELQQALAKLDLLHSEQSAAREQAGAYE--EQLAQMQQKVLDLETEKslLTKQVVEMETHKkhvcEELDAQRAQVQQ 639
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEE--LEKKAEEYEKLK----EKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  640 LERQRSELEEKVRSLAQLQDsqlKNSTVEKeqarqslmEKENIILQMREEQAKEIEILKQTLSSKEEsisiLHEEYeTKF 719
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEK---KLDELEE--------ELAELLKELEELGFESVEELEERLKELEP----FYNEY-LEL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  720 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEEnqrqQIE 799
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRA----ELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  800 SLtgahqRKLDDVIEAWEKKLSQQAAELRD--KHAEQMEEKEQGLGELRQKVRIVQSEKEE 858
Cdd:PRK03918   684 EL-----EKRREEIKKTLEKLKEELEEREKakKELEKLEKALERVEELREKVKKYKALLKE 739
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 787-1467 2.35e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.73  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  787 VSRLEENQRQQIESLtgahQRKLDDVIEAWEKK---LSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEV 863
Cdd:pfam15921   76 IERVLEEYSHQVKDL----QRRLNESNELHEKQkfyLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  864 ARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLR---- 939
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILReldt 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  940 -VSELTGQVQAAEKELQSCKSlhelskksledkslNLKSLLEELASQLDSRCERTKALLEAKTN---ELVCTSRDKADAI 1015
Cdd:pfam15921  232 eISYLKGRIFPVEDQLEALKS--------------ESQNKIELLLQQHQDRIEQLISEHEVEITgltEKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1016 LARLSQCQRHTATVGEALLRrmgQVSELEAQLTQLTEEQRTLKSSFQqvtNQLEEKEKQIKTMKADIEGLLTEKEALQQE 1095
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMR---QLSDLESTVSQLRSELREAKRMYE---DKIEELEKQLVLANSELTEARTERDQFSQE 371

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1096 GG------QQRQAASEKESCITQLKKELAENI------NAVTL--LREELSEKKSEIASLSKQL----SDLGAQLESSIS 1157
Cdd:pfam15921  372 SGnlddqlQKLLADLHKREKELSLEKEQNKRLwdrdtgNSITIdhLRRELDDRNMEVQRLEALLkamkSECQGQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1158 P----SDKAEAISALSKQHEEQELQLQAQLQELSLKVDALS-------------KEKMSALEQVDHWSNKFS---EWKKK 1217
Cdd:pfam15921  452 AiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLEssertvsdltaslQEKERAIEATNAEITKLRsrvDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1218 AQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNK---KFECLKGEMEVRKSKMEKKECDLETALK---- 1290
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQefki 611

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1291 ---TQTARVVELE----DCVTQRKKEVESLNETL---KNYNQQRDTEHSGLVQRLQHLEELGEEKD-------NKVREAE 1353
Cdd:pfam15921  612 lkdKKDAKIRELEarvsDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLSEDYEvlkrnfrNKSEEME 691

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1354 ETVLRLREHVSSLEAELGTVKKELEHVNSS--------------VKSRDGELKALEDKLELESAAKVELKRKaeqkiaai 1419
Cdd:pfam15921  692 TTTNKLKMQLKSAQSELEQTRNTLKSMEGSdghamkvamgmqkqITAKRGQIDALQSKIQFLEEAMTNANKE-------- 763

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025 1420 rKQLLSQMEEKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:pfam15921  764 -KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 375-886 2.82e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 2.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  375 HNKELTALAEQHRTEVEGLQQQQDSLWTERLQ-SLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKL 453
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTKLQQEFNTLESAELRlSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELN 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  454 DKKQMELESVSSELSEALRARDQ----LAEELSVLRGDADKMKQaLEAELEEQRRHHQREVGSISEQQELTVRRaEKALK 529
Cdd:pfam12128  308 GELSAADAAVAKDRSELEALEDQhgafLDADIETAAADQEQLPS-WQSELENLEERLKALTGKHQDVTAKYNRR-RSKIK 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  530 DELSRLGALLDERDEHLRERQARVQDL-EAHLQKSAGELQqalaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETE 608
Cdd:pfam12128  386 EQNNRDIAGIKDKLAKIREARDRQLAVaEDDLQALESELR------EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATAT 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  609 KSLLTKQVVEMEThKKHVCEELDAQRAQVQQLERQRSELeekvRSLAQLQDSQLKNSTVEKEQARQSLMEKE-------- 680
Cdd:pfam12128  460 PELLLQLENFDER-IERAREEQEAANAEVERLQSELRQA----RKRRDQASEALRQASRRLEERQSALDELElqlfpqag 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  681 NIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVL- 759
Cdd:pfam12128  535 TLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALq 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  760 -----------ELSQKEKQFNAQILEMAQANSA--GISDTVSRLEENQRQ---QIESLTGAHQRKLDDVIEAWEKKLSQQ 823
Cdd:pfam12128  615 sarekqaaaeeQLVQANGELEKASREETFARTAlkNARLDLRRLFDEKQSekdKKNKALAERKDSANERLNSLEAQLKQL 694

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  824 AAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEltkEVARLKEAVSGQDVALAGLQGQLEQ 886
Cdd:pfam12128  695 DKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDA---QLALLKAAIAARRSGAKAELKALET 754
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 713-912 3.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  713 EEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAgISDTVSRLEE 792
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE-IAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  793 NQRQQIESLTGAHQRKLDDVIE---------------AWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKE 857
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLAlllspedfldavrrlQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  858 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADL 912
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1221-1910 3.58e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 3.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1221 RLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALKTQTARVVELE 1300
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1301 DCVTQRKKEVESLNETLKNYNQQR-----------DTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAE 1369
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEqlrvkekigelEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELERE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1370 LGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRkaEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSELSAQL 1449
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD--ELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1450 KEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDctHKACKERLCMLQRRLSEKEKLLRRLEQGEG 1529
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--LYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1530 EARPSQPE-------------------------------AQHRALSGKL---------DCTRARQLEDHVLIGCLPEELE 1569
Cdd:TIGR02169  501 ASEERVRGgraveevlkasiqgvhgtvaqlgsvgeryatAIEVAAGNRLnnvvveddaVAKEAIELLKRRKAGRATFLPL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1570 EKMKCSLIVSQPMGEETGNNTGV------KQNWASVVDSVQKTLQEKELTC---QALEQRVKELESDLVRERGA------ 1634
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVdlvefdPKYEPAFKYVFGDTLVVEDIEAarrLMGKYRMVTLEGELFEKSGAmtggsr 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1635 --HRLEVEKLTLKYEKSQSSQQEMDGENKCVEVLEDRPEENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVA 1712
Cdd:TIGR02169  661 apRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLE 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1713 RLQKELRALRRE---HQQELDILKRECE--QEAEEKLKQEQEDLElkhtstlKQLMREFNTQLAQKEQELERTVQETIDK 1787
Cdd:TIGR02169  741 ELEEDLSSLEQEienVKSELKELEARIEelEEDLHKLEEALNDLE-------ARLSHSRIPEIQAELSKLEEEVSRIEAR 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1788 AQEVEAELLESHQEEtQQLHRKIAEKEDDLRRTARRYEEIlDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEESTKDSV 1867
Cdd:TIGR02169  814 LREIEQKLNRLTLEK-EYLEKEIQELQEQRIDLKEQIKSI-EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER 891

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025 1868 TILE-----LQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKN 1910
Cdd:TIGR02169  892 DELEaqlreLERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 670-813 6.54e-05

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 48.12  E-value: 6.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  670 EQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAK 749
Cdd:pfam10168  553 DLAREEIQKRVKLLKLQKEQQLQELQSLEEERKSLSERAEKLAEKYEEIKDKQEKLMRRCKKVLQRLNSQLPVLSDAERE 632

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  750 LKKELE--NTVLE-----LSQKEKQFNAQILEMAQANSAGISDTVSrLEENQRQQIESLTGAHQRKLDDVI 813
Cdd:pfam10168  633 MKKELEtiNEQLKhlanaIKQAKKKMNYQRYQIAKSQSIRKKSSLS-LSEKQRKTIKEILKQLGSEIDELI 702
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
526-813 7.08e-05

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 47.20  E-value: 7.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  526 KALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDL 605
Cdd:COG4372     48 EQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  606 ETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQ-DSQLKNSTVEKEQARQSLMEKENIIL 684
Cdd:COG4372    128 EQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEaEQALDELLKEANRNAEKEEELAEAEK 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  685 QMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQK 764
Cdd:COG4372    208 LIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEA 287

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199025  765 EKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVI 813
Cdd:COG4372    288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILL 336
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 85-671 7.79e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 7.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   85 MLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVITEtkrqmletLELKEDEIAQLRSH 164
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQ--------LSDLESTVSQLRSE 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  165 IKQMTTQGEELREQKEKSERAAFEELEKALStaQKTEDAQRRMKMEMDEQMKAVERASEEERLRLQHELSRV---RQEAA 241
Cdd:pfam15921  333 LREAKRMYEDKIEELEKQLVLANSELTEART--ERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdRDTGN 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  242 SMA----KKNSEEQVAALQKLHAEELASKEQ---ELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEEL 314
Cdd:pfam15921  411 SITidhlRRELDDRNMEVQRLEALLKAMKSEcqgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMT 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  315 ELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQE---SKTQSEHLAvHLEAEKNKHNKELTalaeQHRTEVE 391
Cdd:pfam15921  491 LESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQElqhLKNEGDHLR-NVQTECEALKLQMA----EKDKVIE 565

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  392 GLQQQQDSLwterLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSEL---- 467
Cdd:pfam15921  566 ILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvnag 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  468 SEALRA-------RDQLAEELSVLRGDADKMKQALEAeleeqrrhHQREVGSISEQQELTVRRAEKALKDELSRLgalld 540
Cdd:pfam15921  642 SERLRAvkdikqeRDQLLNEVKTSRNELNSLSEDYEV--------LKRNFRNKSEEMETTTNKLKMQLKSAQSEL----- 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  541 erdEHLRERQARVQDLEAHLQKSA-GELQQALAKLDLLHSEQSAAReqagAYEEQLAQMQQKVLDLETEKSLLTKQVVEM 619
Cdd:pfam15921  709 ---EQTRNTLKSMEGSDGHAMKVAmGMQKQITAKRGQIDALQSKIQ----FLEEAMTNANKEKHFLKEEKNKLSQELSTV 781

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907199025  620 ETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSlAQLQDSQLKNSTVEKEQ 671
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANMEVALDK-ASLQFAECQDIIQRQEQ 832
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
461-658 8.10e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.70  E-value: 8.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  461 ESVSSELSEALRARDQLAEELSVLRGDADkmkqALEAELEEQRRHHQreVGSISEQQELTVRRaekalkdeLSRLGALLD 540
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELE----EAEAALEEFRQKNG--LVDLSEEAKLLLQQ--------LSELESQLA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  541 ERDEHLRERQARVQDLEAHLQKSAGE---------LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSL 611
Cdd:COG3206    230 EARAELAEAEARLAALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 1907199025  612 LTKQVVEMETHkkhvceELDAQRAQVQQLERQRSELEEKVRSLAQLQ 658
Cdd:COG3206    310 EAQRILASLEA------ELEALQAREASLQAQLAQLEARLAELPELE 350
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
81-689 9.84e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.37  E-value: 9.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLD---ERLQELEKMKGMvITETKRQM------LETL 151
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEE-IEELEKELeslegsKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  152 ELK----EDEIAQLRSHIKQMTTQGEELREQKEKSERaaFEELEKALstaqktedaqrrmkmemdEQMKAVERASEEERL 227
Cdd:PRK03918   258 EEKirelEERIEELKKEIEELEEKVKELKELKEKAEE--YIKLSEFY------------------EEYLDELREIEKRLS 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  228 RLQHELSRVRQEAASMAKKNSEeqvaalqklhAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQE 307
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEER----------LEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  308 SLALEELELQKKAilTESENKLQELGQEAEAYRTRILELETSLEKsLQESKT------------QSEHLAVHLEAEKNKH 375
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEE-LKKAKGkcpvcgrelteeHRKELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  376 NKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFqahiqdmnEKTLEKLDK 455
Cdd:PRK03918   465 EKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEY--------EKLKEKLIK 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  456 KQMELESVSSELSEalrardqlAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSrl 535
Cdd:PRK03918   537 LKGEIKSLKKELEK--------LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-- 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  536 gaLLDERDEhLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGayEEQLAQMQQKVLDLETEKSLLTKQ 615
Cdd:PRK03918   607 --LKDAEKE-LEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAE 681

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199025  616 VVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREE 689
Cdd:PRK03918   682 LEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEE 755
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
413-560 9.97e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 9.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  413 QAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKtLEKLDKKQMELESVSSELSEALRARDQLAEElsvlrgdadkmk 492
Cdd:COG2433    379 EEALEELIEKELPEEEPEAEREKEHEERELTEEEEE-IRRLEEQVERLEAEVEELEAELEEKDERIER------------ 445

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025  493 qaLEAELEEQRRhhqrevgsiSEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHL 560
Cdd:COG2433    446 --LERELSEARS---------EERREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELW 502
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 424-980 1.04e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  424 QQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQR 503
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  504 RHHQREvgsisEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSA 583
Cdd:pfam01576   82 SRLEEE-----EERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  584 AREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLaQLQDSQLK 663
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAEL-QAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  664 NSTVEKEQARQSLMEKeniilqMREEQAKEIEILKQtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKL 743
Cdd:pfam01576  236 AQLAKKEEELQAALAR------LEEETAQKNNALKK-IRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTEL 308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  744 LD--------QEAKLKKELENTVLE--LSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIesltgahqrKLDDVI 813
Cdd:pfam01576  309 EDtldttaaqQELRSKREQEVTELKkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKA---------NLEKAK 379

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  814 EAWEKKLSQQAAELRDKHAEQMeEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVS 893
Cdd:pfam01576  380 QALESENAELQAELRTLQQAKQ-DSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIK 458

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  894 LSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSL 973
Cdd:pfam01576  459 LSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAG 538


                   ....*..
gi 1907199025  974 NLKSLLE 980
Cdd:pfam01576  539 TLEALEE 545
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
520-1134 1.06e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  520 TVRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQ 599
Cdd:COG4913    236 DLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  600 QKVLDLETEKSLLTKQvvemetHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLqdsqLKNSTVEKEQARQSLmek 679
Cdd:COG4913    316 ARLDALREELDELEAQ------IRGNGGDRLEQLEREIERLERELEERERRRARLEAL----LAALGLPLPASAEEF--- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  680 eniilqmrEEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELEnTVL 759
Cdd:COG4913    383 --------AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALA-EAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  760 ELSQKEKQFNAQILEmaqansagisdtVSRLEENQRQQIESLTGAH-------QRKLDDVIEA-----WEKKLSQQAAEL 827
Cdd:COG4913    454 GLDEAELPFVGELIE------------VRPEEERWRGAIERVLGGFaltllvpPEHYAAALRWvnrlhLRGRLVYERVRT 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  828 RDKHAEQMEEKEQGLGElrqKVRIVQSE-----KEELTKEVARLK----EAVSGQDVALAgLQGQLEQKSAV----IVSL 894
Cdd:COG4913    522 GLPDPERPRLDPDSLAG---KLDFKPHPfrawlEAELGRRFDYVCvdspEELRRHPRAIT-RAGQVKGNGTRhekdDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  895 SERESQL-QSQVEKLEAdlgcslseklsLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSkksleDKSL 973
Cdd:COG4913    598 IRSRYVLgFDNRAKLAA-----------LEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYS-----WDEI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  974 NLKSLLEELASqldsrcertkalLEAKTNELvctsrDKADAILARLSQcqrhtatvgeallrrmgQVSELEAQLTQLTEE 1053
Cdd:COG4913    662 DVASAEREIAE------------LEAELERL-----DASSDDLAALEE-----------------QLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1054 QRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKESCITQLKKELAENINAVTLLREELSE 1133
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787


                   .
gi 1907199025 1134 K 1134
Cdd:COG4913    788 E 788
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 411-770 1.19e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.04  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  411 QHQAAVEElreKYQQEKdallkeKESLFQAHIQDMNEKTLEKLDKKQmelesvssELSEALRARDQLAEELSVLRGDADK 490
Cdd:pfam17380  279 QHQKAVSE---RQQQEK------FEKMEQERLRQEKEEKAREVERRR--------KLEEAEKARQAEMDRQAAIYAEQER 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  491 MKQALEAELEEQRRHHQREVGSISEQQELTVrraEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 570
Cdd:pfam17380  342 MAMERERELERIRQEERKRELERIRQEEIAM---EISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQ 418

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  571 LAKLDLLHSEQSAAReqagayeeqlaqmQQKVLDLETEKSLLTKQVVEMETHKKHVCEELdaqRAQVQQLERQRSELEEK 650
Cdd:pfam17380  419 KVEMEQIRAEQEEAR-------------QREVRRLEEERAREMERVRLEEQERQQQVERL---RQQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  651 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENiilqMREEQAKEIeilkqtlsskEESISILHEEYETKFKNQEKRMEKIK 730
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEER----KRKLLEKEM----------EERQKAIYEEERRREAEEERRKQQEM 548

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1907199025  731 QKAKEMQETKKKLLDQEAKL-----KKELENTVLELSQKEKQFNA 770
Cdd:pfam17380  549 EERRRIQEQMRKATEERSRLeamerEREMMRQIVESEKARAEYEA 593
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 476-1107 1.63e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 1.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  476 QLAEELSVLRGDADKMKQALEAELEEQRRHHQ--REVGSISEQQELTVRRAEKALKDELSRLGALLDERDEHLRERQARV 553
Cdd:TIGR00618  230 HLREALQQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  554 QDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAyeEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQ 633
Cdd:TIGR00618  310 QRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRL--LQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  634 RAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQArqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHE 713
Cdd:TIGR00618  388 KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQL---AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  714 EYETK-FKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnAQILEMAQANSAGISDTVSRLEE 792
Cdd:TIGR00618  465 AQSLKeREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD--IDNPGPLTRRMQRGEQTYAQLET 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  793 ----------NQRQQIESLTGAHQRKLDDVIEAWEK---------KLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQ 853
Cdd:TIGR00618  543 seedvyhqltSERKQRASLKEQMQEIQQSFSILTQCdnrskedipNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  854 SE--KEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcsLSEKLSLQEELAELKL 931
Cdd:TIGR00618  623 PEqdLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLA-----LQKMQSEKEQLTYWKE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  932 LADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCtsrdk 1011
Cdd:TIGR00618  698 MLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTA----- 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1012 ADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQ--------LTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIE 1083
Cdd:TIGR00618  773 ALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdediLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852

                          650       660
                   ....*....|....*....|....
gi 1907199025 1084 GLLTEKEALQQEGGQQRQAASEKE 1107
Cdd:TIGR00618  853 KYEECSKQLAQLTQEQAKIIQLSD 876
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 459-675 1.68e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.36  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  459 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQEltvrraekALKDELSRLGAL 538
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYN-ELQAELEALQAEIDKLQAEIA--------EAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  539 LDERDEHLRERQARVQDLEAHLqkSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVE 618
Cdd:COG3883     88 LGERARALYRSGGSVSYLDVLL--GSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAE 165

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025  619 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 675
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
PRK12704 PRK12704
phosphodiesterase; Provisional
 1704-1835 1.88e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 46.31  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1704 KQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMREFNtQLAQKEQELERtvqe 1783
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1907199025 1784 tidkaqevEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEM 1835
Cdd:PRK12704   101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 888-1119 1.97e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 1.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  888 SAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKS 967
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  968 LEDKSLNLKSLLeeLASQLDSRCERTKALLEAKtnelvctSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQL 1047
Cdd:COG4942     99 LEAQKEELAELL--RALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199025 1048 TQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEgllTEKEALQQEGGQQRQAASEKESCITQLKKELAE 1119
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
mukB PRK04863
chromosome partition protein MukB;
410-675 2.16e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  410 QQHQAAVEELREKYQQEKDAL--LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEALR-------ARDQLAEE 480
Cdd:PRK04863   847 VELERALADHESQEQQQRSQLeqAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEAEEAKRfvqqhgnALAQLEPI 926

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  481 LSVLRGDadkmkqalEAELEEQRRHHQRevgsiSEQQELTVRRAEKALKDelsrlgalLDERDEHLRERQArVQDLEAhl 560
Cdd:PRK04863   927 VSVLQSD--------PEQFEQLKQDYQQ-----AQQTQRDAKQQAFALTE--------VVQRRAHFSYEDA-AEMLAK-- 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  561 qksAGELQQAL-AKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEME------------------- 620
Cdd:PRK04863   983 ---NSDLNEKLrQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKqelqdlgvpadsgaeerar 1059

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025  621 THKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQS 675
Cdd:PRK04863  1060 ARRDELHARLSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVNA 1114
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 447-661 2.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  447 EKTLEKLDKKQMELESVSSELSEALRARDQLAEELSVLRGDADKMKQ---ALEAELEEQRRHHQREVGSISEQQELTVRR 523
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQelaALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  524 AEKALK-DELSRLGALLDERD-EHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAgayEEQLAQMQQK 601
Cdd:COG4942    110 LRALYRlGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL---EALLAELEEE 186

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  602 VLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQ 661
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1708-1919 2.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1708 SKEVARLQKELRALRREHQQELDILKREceQEAEEKLKQEQEDLELKhTSTLKQLMREFNTQLAQKEQELERT------V 1781
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAAL--KKEEKALLKQLAALERR-IAALARRIRALEQELAALEAELAELekeiaeL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1782 QETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARR---YEEILDAREEEMTG------KVTDLQTQLEELQKK 1852
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEElradlaELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025 1853 YQQRLEQEESTKDSVT--ILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEKNACAATVGTP 1919
Cdd:COG4942    176 LEALLAELEEERAALEalKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
Golgin_A5 pfam09787
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ...
 464-624 2.84e-04

Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.


Pssm-ID: 462900 [Multi-domain]  Cd Length: 305  Bit Score: 45.13  E-value: 2.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  464 SSELSEALRARDQLAEELSVLRGDAdkmkQALEAELEEQRRHHQREVGSISEQ------QELTVRRAEKALKDELSRLGA 537
Cdd:pfam09787   46 TLELEELRQERDLLREEIQKLRGQI----QQLRTELQELEAQQQEEAESSREQlqeleeQLATERSARREAEAELERLQE 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  538 LLDERDEHLRE----RQARVQDLEAHLQKSAGELQQAlaklDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLT 613
Cdd:pfam09787  122 ELRYLEEELRRskatLQSRIKDREAEIEKLRNQLTSK----SQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLV 197

                          170
                   ....*....|.
gi 1907199025  614 KQVVEMETHKK 624
Cdd:pfam09787  198 LQLERMEQQIK 208
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 193-434 3.12e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  193 ALSTAQKTEDAQRRMKmEMDEQMKAVER---ASEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEeLASKE 267
Cdd:COG4942     15 AAAQADAAAEAEAELE-QLQQEIAELEKelaALKKEEKALLKQLAALERRIAALARRirALEQELAALEAELAE-LEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  268 QELSRRLEARERELQEQMRIALEKSRSEYLKLTqeKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRILELE 347
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  348 TSLEKsLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSlwTERLQSLSQQHQAAVEELREKYQQEK 427
Cdd:COG4942    171 AERAE-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE--AEELEALIARLEAEAAAAAERTPAAG 247


                   ....*..
gi 1907199025  428 DALLKEK 434
Cdd:COG4942    248 FAALKGK 254
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
520-1004 3.14e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 3.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  520 TVRRAEKALKDELSRLG---ALLDERDEHLRERQARVQDLEAHLQKSAGELQQA---LAKLDLLHSEQSAAREQAGAYEE 593
Cdd:PRK03918   173 EIKRRIERLEKFIKRTEnieELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  594 QLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVcEELDAQRAQVQQLERQRSELEEKVRSLAQLQD--SQLKNSTVEKEQ 671
Cdd:PRK03918   253 SKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYIKLSEFYEEYLDELREIEKRLSrlEEEINGIEERIK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  672 ARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK 751
Cdd:PRK03918   332 ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKIT 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  752 KELENTVLELSQKEKQFNA---------------------QILEMAQANSAGISDTVSRLEENQRQQIESLTGAH----- 805
Cdd:PRK03918   412 ARIGELKKEIKELKKAIEElkkakgkcpvcgrelteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEkvlkk 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  806 ------QRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSE---KEELTKEVARLKEAVSGQDVA 876
Cdd:PRK03918   492 eselikLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKElekLEELKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  877 LAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 956
Cdd:PRK03918   572 LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  957 CKSL-----HELSKKSLEDKSLNLKSLLEELaSQLDSRCERTKALLEAKTNEL 1004
Cdd:PRK03918   652 LEKKyseeeYEELREEYLELSRELAGLRAEL-EELEKRREEIKKTLEKLKEEL 703
PLN02939 PLN02939
transferase, transferring glycosyl groups
 525-748 3.18e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.05  E-value: 3.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  525 EKALKDELSRLGALLDERDEHLR---ERQARVQDLEAHLQKSAGELQQALA-----------KLDLLHSEQSAAREQAGA 590
Cdd:PLN02939   165 KEALQGKINILEMRLSETDARIKlaaQEKIHVEILEEQLEKLRNELLIRGAteglcvhslskELDVLKEENMLLKDDIQF 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  591 YEEQLAQMQ---QKVLDLETEKSLLTKQVVEMEthkkhvCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSqlknSTV 667
Cdd:PLN02939   245 LKAELIEVAeteERVFKLEKERSLLDASLRELE------SKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDR----ATN 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  668 EKEQARQSLMEKENI--ILQMREEQAKE----------IEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKE 735
Cdd:PLN02939   315 QVEKAALVLDQNQDLrdKVDKLEASLKEanvskfssykVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSK 394

                          250
                   ....*....|....
gi 1907199025  736 M-QETKKKLLDQEA 748
Cdd:PLN02939   395 LkEESKKRSLEHPA 408
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 458-568 4.16e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 45.46  E-value: 4.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  458 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQEltvrrAEKALKDELSRLGA 537
Cdd:COG0542    404 MEIDSKPEELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARWE-----AEKELIEEIQELKE 478

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1907199025  538 LLDERDEHLRERQARVQDLEAHLQKSAGELQ 568
Cdd:COG0542    479 ELEQRYGKIPELEKELAELEEELAELAPLLR 509
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 80-463 4.27e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   80 AKTLEMLQQRVKRQENLLQRCKETIGSHKEQCALLLSEKEALQEQLDERLQELEKMKGMVI-----TETKRQMLETLELK 154
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAelleeAALLEAALAELLEE 485

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  155 EDEIAQLRSHIKQMTTQGEELREQ-KEKSERAAFEELEKALSTAQKTEDAQRRmkmemdeqmkAVERASEEERLRLQHEL 233
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEA----------ALEAALAAALQNIVVED 555

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  234 SRVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEE 313
Cdd:COG1196    556 DEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  314 LELQKKAILTESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGL 393
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  394 QQQQDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQdmnEKTLEKLDKKQMELESV 463
Cdd:COG1196    716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL---ERELERLEREIEALGPV 782
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1680-1871 4.43e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 4.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1680 QSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTL 1759
Cdd:COG3206    204 KNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELS 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1760 KQL------MREFNTQLAQKEQELERTVQETIDKAqEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEIldAREe 1833
Cdd:COG3206    284 ARYtpnhpdVIALRAQIAALRAQLQQEAQRILASL-EAELEALQAREASLQAQLAQLEARLAELPELEAELRRL--ERE- 359

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1907199025 1834 emtgkVTDLQTQLEELQKKYQQRLEQEESTKDSVTILE 1871
Cdd:COG3206    360 -----VEVARELYESLLQRLEEARLAEALTVGNVRVID 392
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
718-1319 4.87e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 4.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqilemaqansagisdtVSRLEENQRQQ 797
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLRE-------------------INEISSELPEL 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  798 IESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKeqgLGELRQKVRIVQSEKEELTKEVARLKEaVSGQDVAL 877
Cdd:PRK03918   220 REELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEK---IRELEERIEELKKEIEELEEKVKELKE-LKEKAEEY 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  878 AGLQGQLEQKSAVIVSLSERESQLQSQVEKLEAdlgcSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSC 957
Cdd:PRK03918   296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  958 KSLHELSKKSLEDKSLNLKSLLEELasqldsrcERTKALLEAKTNElvctsrdkadaILARLSQCQRHTATVGEALLRRM 1037
Cdd:PRK03918   372 EELERLKKRLTGLTPEKLEKELEEL--------EKAKEEIEEEISK-----------ITARIGELKKEIKELKKAIEELK 432

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1038 GQVSELEAQLTQLTEEQRtlKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEscITQLKKEL 1117
Cdd:PRK03918   433 KAKGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKE--LAEQLKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1118 AENINAVTLlrEELSEKKSEIASLSKQLSDLGAQLESSispSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEK 1197
Cdd:PRK03918   509 EEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSL---KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1198 MSALEQVDHWSNKFSEWKKKaQSRLAQHQSTIKDLQAQLDVKATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRK-S 1276
Cdd:PRK03918   584 FESVEELEERLKELEPFYNE-YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyE 662

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|...
gi 1907199025 1277 KMEKKECDLETALKTQTARVVELEDCVTQRKKEVESLNETLKN 1319
Cdd:PRK03918   663 ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 417-1203 5.66e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 5.66e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  417 EELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELES---VSSELSEALRARDQLAEELSVLRGDADKMKQ 493
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEyllYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  494 ALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGAL-LDERDEHLRERQARVQDLEAHLQKSAGELQQALA 572
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLkLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  573 KLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSELEEKVR 652
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLE 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  653 SLAQLqdsqLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEKIKQK 732
Cdd:pfam02463  419 DLLKE----EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  733 AKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRK---- 808
Cdd:pfam02463  495 LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALtelp 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  809 ---------LDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 879
Cdd:pfam02463  575 lgarklrllIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  880 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQSCKS 959
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  960 LHEL--------SKKSLEDKSLNLKSLLEELASQLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTATVGE 1031
Cdd:pfam02463  735 NEELkllkqkidEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEA 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1032 ALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQ--RQAASEKESC 1109
Cdd:pfam02463  815 ELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQklKDELESKEEK 894

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1110 ITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISALSKQHEEQELQLQAQLQELSLK 1189
Cdd:pfam02463  895 EKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGK 974

                          810
                   ....*....|....
gi 1907199025 1190 VDALSKEKMSALEQ 1203
Cdd:pfam02463  975 VNLMAIEEFEEKEE 988
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
977-1153 6.36e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 6.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  977 SLLEELASQLDS-RCERTKALLEAKTNELvctsRDKADAILARLSQCQRHTATVGEALLRRMGQVSELE-AQLTQLTEEQ 1054
Cdd:COG4913    272 AELEYLRAALRLwFAQRRLELLEAELEEL----RAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLEREI 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1055 RTLKSSFQQVTNQLEEKEKQIKTMKADIEGLLTEKEALQQEGGQQRQAASEKEScitQLKKELAENINAVTLLREELSEK 1134
Cdd:COG4913    348 ERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELE---ALEEALAEAEAALRDLRRELREL 424

                          170
                   ....*....|....*....
gi 1907199025 1135 KSEIASLSKQLSDLGAQLE 1153
Cdd:COG4913    425 EAEIASLERRKSNIPARLL 443
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 921-1161 6.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 6.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  921 SLQEELAELKLLADKSQLRVSELTGQVQAAEKELqsckslhelskKSLEDKSLNLKSLLEELASQLDSRcERTKALLEAK 1000
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQL-----------AALERRIAALARRIRALEQELAAL-EAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1001 TNELVCTSRDKADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLT---QLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1077
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1078 MKADIEGLLTEKEALQQEggqQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESSIS 1157
Cdd:COG4942    172 ERAELEALLAELEEERAA---LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ....
gi 1907199025 1158 PSDK 1161
Cdd:COG4942    249 AALK 252
PRK09039 PRK09039
peptidoglycan -binding protein;
845-986 6.90e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.19  E-value: 6.90e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  845 LRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQE 924
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199025  925 ELAELKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKslEDKSLNLKslLEELASQL 986
Cdd:PRK09039   124 ELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEK--RDRESQAK--IADLGRRL 181
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1212-1909 7.23e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 7.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1212 SEWKKKAQSRLAQHQSTIKDLQAQLDVKATDAREKeeqicllKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLETALkt 1291
Cdd:pfam02463  175 LKKLIEETENLAELIIDLEELKLQELKLKEQAKKA-------LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQEL-- 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1292 QTARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKdNKVREAEETVLRLREHVSSLEAELG 1371
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELK-SELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1372 TVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEK--TQRYAKDTENRLSELSAQL 1449
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESerLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1450 KEREKQVHSLEDKL-----KNLESSPHPEVPAVSRSMQSVAASPEQEAPDSQDCTHKACKERLCMLQRRLSEKEKLLRRL 1524
Cdd:pfam02463  405 KEAQLLLELARQLEdllkeEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1525 EQGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVLIGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1604
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1605 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSqQEMDGENKCVEVLEDRPEENSQSHEIQSNVG 1684
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKAT-LEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1685 TVDGLR--SDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQL 1762
Cdd:pfam02463  644 KESGLRkgVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1763 MREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDL 1842
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025 1843 QTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKRYEK 1909
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
185-658 7.34e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 7.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  185 AAFEELEKALSTAQKTEDAQRRMKMEMDEqmkaveraSEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHAEELA 264
Cdd:COG4717     71 KELKELEEELKEAEEKEEEYAELQEELEE--------LEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  265 SKEQELsRRLEARERELQEQMRiALEKSRSEYlkltQEKEQQESLALEELELQKKAILTESENKLQELGQEAEAYRTRIL 344
Cdd:COG4717    143 ELPERL-EELEERLEELRELEE-ELEELEAEL----AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  345 ELETSLEkSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLWTERLQSLSQQHQAAVEELREKYQ 424
Cdd:COG4717    217 EAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAR 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  425 QEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSseLSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRR 504
Cdd:COG4717    296 EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLS--PEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  505 HHQREVGSISEqqeltvrraekalkDELSRLGalldERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL--LHSEQS 582
Cdd:COG4717    374 ALLAEAGVEDE--------------EELRAAL----EQAEEYQELKEELEELEEQLEELLGELEELLEALDEeeLEEELE 435

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199025  583 AAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQvvemethkkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQ 658
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQLEED------------GELAELLQELEELKAELRELAEEWAALKLAL 499
COG5022 COG5022
Myosin heavy chain [General function prediction only];
87-687 7.68e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 44.68  E-value: 7.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   87 QQRVKRQENLLQRCKETIGShkeqcallLSEKEALQEQLDERLQELEKmkgmvitETKRQMLETLELKEDEIAQLRSHIK 166
Cdd:COG5022    874 AQRVELAERQLQELKIDVKS--------ISSLKLVNLELESEIIELKK-------SLSSDLIENLEFKTELIARLKKLLN 938

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  167 QMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EDAQRRMKMEMDEQMKAverasEEERLRLQHELS--RVRQEAASM 243
Cdd:COG5022    939 NIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKA-----NSELKNFKKELAelSKQYGALQE 1013

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  244 AKKNSEEQVAALQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAIL- 322
Cdd:COG5022   1014 STKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLl 1093

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  323 ---TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKE---------LTALAEQHRTEV 390
Cdd:COG5022   1094 ktiNVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLqleldglfwEANLEALPSPPP 1173

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  391 EGLQQQ----QDSLWTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESL-FQAHIQDMNEkTLEKLDkkqmelESVSS 465
Cdd:COG5022   1174 FAALSEkrlyQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKkLISEGWVPTE-YSTSLK------GFNNL 1246

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  466 ELSEALRARDQLAEELSVLRGDADKMK-QALEAELEEQRRHHQREVGSISEQQELTVRRAEKALK--DELSRLGALLDER 542
Cdd:COG5022   1247 NKKFDTPASMSNEKLLSLLNSIDNLLSsYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsaTEVNYNSEELDDW 1326

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  543 DehlreRQARVQDLEAHLQksagELQQALAKLDLLHSEQSAAREqagayeeqLAQMQQKVLDLETEKSLLTKQVVEMETH 622
Cdd:COG5022   1327 C-----REFEISDVDEELE----ELIQAVKVLQLLKDDLNKLDE--------LLDACYSLNPAEIQNLKSRYDPADKENN 1389

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025  623 -KKHVCEELDAQRAQvqqlERQRSELEEKVRSLAQLQDS--------QLKNSTVEKEQARQSLME---KENIILQMR 687
Cdd:COG5022   1390 lPKEILKKIEALLIK----QELQLSLEGKDETEVHLSEIfseeksliSLDRNSIYKEEVLSSLSAlltKEKIALLDR 1462
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 24-726 7.72e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.57  E-value: 7.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   24 ISVLQTQVSLLKQRLQNGPMNVDAPKPLPPGELQAEVHGDTEKMEGVGEPVGGGTSAKTLEMLQQRVKRQENLLQRCKET 103
Cdd:TIGR00618  196 AELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQ 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  104 IGSHKE-QCALLLSEKEALQEQLDERLQELEKMKGMVITETKRQM--LETLELKEDEIAQLRSHIKQMTTQGEELREQKE 180
Cdd:TIGR00618  276 EAVLEEtQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMrsRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEI 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  181 KSERAAFEELEKALSTAQKTEDAQRRMKMEMDEQmkaverASEEERLRLQHELSRVRQEAASMAKKNSEEQVAALQKLHA 260
Cdd:TIGR00618  356 HIRDAHEVATSIREISCQQHTLTQHIHTLQQQKT------TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  261 EELASKEQELSRRLEARERElQEQMRIALEKSRSEYLKLTQEKEQQESLALEELElQKKAILTESENKLQELGQEAEAYR 340
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITC-TAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLC 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  341 TRILELETSLEKSLQESKTQSEHLAvhLEAEKNKHNKELTALAEQHRTEVEGLQ--QQQDSLWTERLQSLSQQHQAAVEE 418
Cdd:TIGR00618  508 GSCIHPNPARQDIDNPGPLTRRMQR--GEQTYAQLETSEEDVYHQLTSERKQRAslKEQMQEIQQSFSILTQCDNRSKED 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  419 LrEKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDK--------KQMELESVSSELSEALRARDQLAEELSvlrgdADK 490
Cdd:TIGR00618  586 I-PNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLqpeqdlqdVRLHLQQCSQELALKLTALHALQLTLT-----QER 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  491 MKQALEAELEEQRRHHQREVGSISEQQELtvRRAEKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQA 570
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSE--KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  571 LAKLDllHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTkqvvEMETHKKHVCEELDAQRAQVQQLERQRSELEEK 650
Cdd:TIGR00618  738 EDALN--QSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGA----ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQE 811

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907199025  651 VRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRM 726
Cdd:TIGR00618  812 IPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
121-548 7.92e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 7.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  121 LQEQLDERLQELEKMKGMVIT------ETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKE--KSERAAFEELEK 192
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPElnlkelKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEelREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  193 ALSTAQKTEDAQRRMKmEMDEQMKAVERAsEEERLRLQHELSRVRQEAASMAKK--NSEEQVAALQKLHAEELASKEQEL 270
Cdd:COG4717    127 LLPLYQELEALEAELA-ELPERLEELEER-LEELRELEEELEELEAELAELQEEleELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  271 SRRLEARERELQEQmRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAIL---------------------------- 322
Cdd:COG4717    205 QQRLAELEEELEEA-QEELEELEEELEQLENELEAAALEERLKEARLLLLIAaallallglggsllsliltiagvlflvl 283

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  323 --------------TESENKLQELGQEAEAYRTRILELETSLEKSLQESKTQSEHLAVHLEAEKNKHNKELTALAEQHRT 388
Cdd:COG4717    284 gllallflllarekASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  389 EVEGLQQQQDSLWT-------ERLQSLSQQHQAAvEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQMELE 461
Cdd:COG4717    364 QLEELEQEIAALLAeagvedeEELRAALEQAEEY-QELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELE 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  462 SVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDElsRLGALLDE 541
Cdd:COG4717    443 ELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE--RLPPVLER 520


                   ....*..
gi 1907199025  542 RDEHLRE 548
Cdd:COG4717    521 ASEYFSR 527
RecN COG0497
DNA repair ATPase RecN [Replication, recombination and repair];
1705-1906 9.70e-04

DNA repair ATPase RecN [Replication, recombination and repair];


Pssm-ID: 440263 [Multi-domain]  Cd Length: 555  Bit Score: 43.91  E-value: 9.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1705 QKLSKEVARLQKELRALR---REHQQELDILKRECEQEAEEKLKQ-EQEDLE-----LKHTSTLKQLMREFNTQLAQKEQ 1775
Cdd:COG0497    161 REAYRAWRALKKELEELRadeAERARELDLLRFQLEELEAAALQPgEEEELEeerrrLSNAEKLREALQEALEALSGGEG 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1776 ELERTVQETIDKAQEVE---------AELLESHQEETQqlhrkiaekedDLRRTARRYEEILDAREEEMTgKVTDLQTQL 1846
Cdd:COG0497    241 GALDLLGQALRALERLAeydpslaelAERLESALIELE-----------EAASELRRYLDSLEFDPERLE-EVEERLALL 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1847 EELQKKYQQRLEQeestkdsvtILELQTQLAQKTTLISDSKLKEQELREQVHNLEDRLKR 1906
Cdd:COG0497    309 RRLARKYGVTVEE---------LLAYAEELRAELAELENSDERLEELEAELAEAEAELLE 359
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 566-784 1.02e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  566 ELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRS 645
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  646 ELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKR 725
Cdd:COG3883     97 RSGGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025  726 MEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSAGIS 784
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
827-1070 1.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  827 LRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKeavsgQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVE 906
Cdd:COG3206    162 LEQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFR-----QKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  907 KLEADLgcslsEKLSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQsckslhELSKKSLED--KSLNLKSLLEELAS 984
Cdd:COG3206    237 EAEARL-----AALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELA------ELSARYTPNhpDVIALRAQIAALRA 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  985 QLDSRCERTKALLEAKTNELvctsRDKADAILARLSQcqrhtatvgeaLLRRMGQVSELEAQLTQLTEEQRTLKSSFQQV 1064
Cdd:COG3206    306 QLQQEAQRILASLEAELEAL----QAREASLQAQLAQ-----------LEARLAELPELEAELRRLEREVEVARELYESL 370


                   ....*.
gi 1907199025 1065 TNQLEE 1070
Cdd:COG3206    371 LQRLEE 376
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
525-992 1.59e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  525 EKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQ--KV 602
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKllQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  603 LDLETEKSLLTKQVVEMETHKkhvcEELDAQRAQVQQLERQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKeni 682
Cdd:COG4717    128 LPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE--- 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  683 ilqmREEQAKEIEILKQTLSSKEESISILHEEYETkfknqekrmekiKQKAKEMQETKKKLldQEAKLKKELENTVLELS 762
Cdd:COG4717    201 ----LEELQQRLAELEEELEEAQEELEELEEELEQ------------LENELEAAALEERL--KEARLLLLIAAALLALL 262

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  763 QKEKQFNAQILEMAQANSAGISDTVSRLEENQRQQIESLTGAHQRKLDDVIEAWEKKLSQQAAELRDKHAEQMEEKEQGL 842
Cdd:COG4717    263 GLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  843 GELRQKVRIVQSEKEELTKEvARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSL 922
Cdd:COG4717    343 LDRIEELQELLREAEELEEE-LQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199025  923 QEELAELKLLADKSQLR--VSELTGQVQAAEKELQSCKslHELSKKSLEDKSLNLKSLLEELASQLDSRCER 992
Cdd:COG4717    422 LEALDEEELEEELEELEeeLEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEE 491
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 720-956 1.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  720 KNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTVLELSQKEKQfnaqiLEMAQANSAGISDTVSRLEENQRQQIE 799
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-----IRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  800 SLTgAHQRKLDDVIEAWEKKLSQQAAELRdKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVARLKEAVSGQDVALAG 879
Cdd:COG4942     98 ELE-AQKEELAELLRALYRLGRQPPLALL-LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025  880 LQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGcslseklSLQEELAELKLLADKSQLRVSELTGQVQAAEKELQS 956
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELA-------ELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
46 PHA02562
endonuclease subunit; Provisional
 599-838 1.64e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 43.46  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  599 QQKVLDLETEKSLLTKQVvemETHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQDS---QLKNSTVEKEqarqs 675
Cdd:PHA02562   180 NQQIQTLDMKIDHIQQQI---KTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEEltdELLNLVMDIE----- 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  676 lmEKENIILQMREEQAKeieilkqtLSSKEESISILHEEYET---------KFKNQEKRMEKIKQKAKEMQETKKKLLDQ 746
Cdd:PHA02562   252 --DPSAALNKLNTAAAK--------IKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTA 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  747 EAKLkKELENTVLELSQKEKQFNAQIlemaQANSAGISDTVSRLEENQRqQIESLTGAHQRKLDDVieaweKKLSQQAAE 826
Cdd:PHA02562   322 IDEL-EEIMDEFNEQSKKLLELKNKI----STNKQSLITLVDKAKKVKA-AIEELQAEFVDNAEEL-----AKLQDELDK 390

                          250
                   ....*....|..
gi 1907199025  827 LRDKHAEQMEEK 838
Cdd:PHA02562   391 IVKTKSELVKEK 402
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1732-1814 1.70e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 43.28  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1732 LKRECEQEAEE--KLKQEQEDLELKhtstLKQLMREFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRK 1809
Cdd:PRK00409   528 LERELEQKAEEaeALLKEAEKLKEE----LEEKKEKLQEEEDKLLEEAEKEAQQAIKEAKKEADEIIKELRQLQKGGYAS 603


                   ....*
gi 1907199025 1810 IAEKE 1814
Cdd:PRK00409   604 VKAHE 608
COG5022 COG5022
Myosin heavy chain [General function prediction only];
587-1138 1.71e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  587 QAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQ----VQQLERQRSELEEKVRSLAQL--QDS 660
Cdd:COG5022    823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIYLQsaqrVELAERQLQELKIDVKSISSLklVNL 902

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  661 QLKNSTVEKEQARQSLMEKENIILQ---------------------MREEQAKEIEIL--KQTLSSKEESISILHEEYET 717
Cdd:COG5022    903 ELESEIIELKKSLSSDLIENLEFKTeliarlkkllnnidleegpsiEYVKLPELNKLHevESKLKETSEEYEDLLKKSTI 982

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLK--KELENTVLELSQKEKQFNAQILEMAQANSagISDTVSRLEENQR 795
Cdd:COG5022    983 LVREGNKANSELKNFKKELAELSKQYGALQESTKqlKELPVEVAELQSASKIISSESTELSILKP--LQKLKGLLLLENN 1060

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  796 QQIESLTGAHQRKLDDVI-----------EAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEELTKEVA 864
Cdd:COG5022   1061 QLQARYKALKLRRENSLLddkqlyqlestENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVN 1140

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  865 RLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEEL-AELKLLADKS------Q 937
Cdd:COG5022   1141 TLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLkNELIALFSKIfsgwprG 1220

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  938 LRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSLNLKSLLEELASQLDSRC--ERTKALLEAKTNELVCTSRDKADAI 1015
Cdd:COG5022   1221 DKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSsyKLEEEVLPATINSLLQYINVGLFNA 1300

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1016 LArlSQCQRHTATVGEAL----------LRRMGqVSELEAQLTQLTEEQRTLkssfQQVTNQLEEKEKQIKTMK----AD 1081
Cdd:COG5022   1301 LR--TKASSLRWKSATEVnynseelddwCREFE-ISDVDEELEELIQAVKVL----QLLKDDLNKLDELLDACYslnpAE 1373

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025 1082 IEGLLTEKEALQQEGG--QQRQAASEKESCITQLKKELAENINAVTLLREELSEKKSEI 1138
Cdd:COG5022   1374 IQNLKSRYDPADKENNlpKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFSEEKSLI 1432
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 356-600 1.87e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 43.67  E-value: 1.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  356 ESKTQSEHLAVHLE---AEKNKHNKELTALAEQHRTEVEGlQQQQDSLWTERLQSLSQQHQAaveeLREKYQQEKDALLK 432
Cdd:NF012221  1539 ESSQQADAVSKHAKqddAAQNALADKERAEADRQRLEQEK-QQQLAAISGSQSQLESTDQNA----LETNGQAQRDAILE 1613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  433 EKESlFQAHIQDMNeKTLEKLDkkqmELESVSSELSEalRARDQLAEE-LSVLRGDADKMKQALEAELEEQRRHH---QR 508
Cdd:NF012221  1614 ESRA-VTKELTTLA-QGLDALD----SQATYAGESGD--QWRNPFAGGlLDRVQEQLDDAKKISGKQLADAKQRHvdnQQ 1685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  509 EVGSISEQQELTVRRAEKalkdelSRLGALLDERDEHlreRQARVQDLEAHLQKSAGELQQALAKLDLLHSEQSAAREQA 588
Cdd:NF012221  1686 KVKDAVAKSEAGVAQGEQ------NQANAEQDIDDAK---ADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS 1756

                          250
                   ....*....|..
gi 1907199025  589 GAyEEQLAQMQQ 600
Cdd:NF012221  1757 AA-ENKANQAQA 1767
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1284-1826 2.17e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 2.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1284 DLETALKTQTArvvELEDCVTQRKKEVESLNETlknynQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHV 1363
Cdd:PRK02224   210 GLESELAELDE---EIERYEEQREQARETRDEA-----DEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1364 SSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAEQKIAAIrKQLLSQMEEKTQRyAKDTENRLS 1443
Cdd:PRK02224   282 RDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAA-QAHNEEAESLRED-ADDLEERAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1444 ELSAQLKEREKQVHSLEDKLKNLESSPHPEVPAVSRSMQSVAASPEQeaPDSQDCTHKACKERLCMLQRRLSEKEKLLRR 1523
Cdd:PRK02224   360 ELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD--LGNAEDFLEELREERDELREREAELEATLRT 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1524 LEQGEGEARPSQPEaqhralsGKldCTRARQ-LEDHVLIGCLPEELEEKMKCSLIVSQPmgEETGNNTGVKQNWASVVDS 1602
Cdd:PRK02224   438 ARERVEEAEALLEA-------GK--CPECGQpVEGSPHVETIEEDRERVEELEAELEDL--EEEVEEVEERLERAEDLVE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1603 VQKTLQEKELTCQALEQRVKElesdlvrergaHRLEVEKLTLKYEKSQSSQQEMDGEnkCVEVLEDRPEENSQSHEIQSN 1682
Cdd:PRK02224   507 AEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE--AEEKREAAAEAEEEAEEAREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1683 VGTVDGLRSDLESKLTGAERDKQKLSK-EVARLQKELRALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQ 1761
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAiADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEARE 653

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907199025 1762 LMREFNTQLAQKEQELERTVQETIDKAQEVEAelLESHQEETQQLHRKIAEKEDDLRRTARRYEE 1826
Cdd:PRK02224   654 DKERAEEYLEQVEEKLDELREERDDLQAEIGA--VENELEELEELRERREALENRVEALEALYDE 716
mukB PRK04863
chromosome partition protein MukB;
467-926 2.20e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 2.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  467 LSEALRARDQLAEELSVLRGDADKMKQALEAEL----------EEQRRHHQREVGSIseQQELTvrRAEKALKDELSRLG 536
Cdd:PRK04863   235 MEAALRENRMTLEAIRVTQSDRDLFKHLITESTnyvaadymrhANERRVHLEEALEL--RRELY--TSRRQLAAEQYRLV 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  537 ALLDERDEHLRERQARVQDLEA---HL---------QKSAGELQQALAKLDLLHSEQSAAREQAgayeeqlaqmQQKVLD 604
Cdd:PRK04863   311 EMARELAELNEAESDLEQDYQAasdHLnlvqtalrqQEKIERYQADLEELEERLEEQNEVVEEA----------DEQQEE 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  605 LETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLeRQRSELEEKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIIL 684
Cdd:PRK04863   381 NEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQY-QQAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEELL 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  685 QmreeqakeieiLKQTLSSKEESISILHEEYETKFK-NQEKRMEKIKQKAKEM---QETKKKLLDQEAKLKKELEntvlE 760
Cdd:PRK04863   460 S-----------LEQKLSVAQAAHSQFEQAYQLVRKiAGEVSRSEAWDVARELlrrLREQRHLAEQLQQLRMRLS----E 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  761 LSQKEKQFNAQILEMAQANSagisdtVSRLEENQRQQIESLTGAHQRKLDDvieawekkLSQQAAELRDKHAEQMEEKEQ 840
Cdd:PRK04863   525 LEQRLRQQQRAERLLAEFCK------RLGKNLDDEDELEQLQEELEARLES--------LSESVSEARERRMALRQQLEQ 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  841 gLGELRQKVRIVQSEKEELTKEVARLKEAV-----SGQDVaLAGLQGQLEQKSAVIVS---LSERESQLQSQVEKLEADL 912
Cdd:PRK04863   591 -LQARIQRLAARAPAWLAAQDALARLREQSgeefeDSQDV-TEYMQQLLERERELTVErdeLAARKQALDEEIERLSQPG 668

                          490
                   ....*....|....
gi 1907199025  913 GCSLSEKLSLQEEL 926
Cdd:PRK04863   669 GSEDPRLNALAERF 682
PRK11281 PRK11281
mechanosensitive channel MscK;
1701-1904 2.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 2.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1701 ERDKQKLSKEVARLQKELRalrrEHQQELDILKRECEQEAEEKL-KQEQEDLELKHTSTLKQL------MREFNTQLAQK 1773
Cdd:PRK11281    79 KEETEQLKQQLAQAPAKLR----QAQAELEALKDDNDEETRETLsTLSLRQLESRLAQTLDQLqnaqndLAEYNSQLVSL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1774 EQELERtVQETIDKA----QEVEAELLESHQEET-------QQLHRKIA--EKEDDLRRT----ARRYEEILDAREEEMT 1836
Cdd:PRK11281   155 QTQPER-AQAALYANsqrlQQIRNLLKGGKVGGKalrpsqrVLLQAEQAllNAQNDLQRKslegNTQLQDLLQKQRDYLT 233

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907199025 1837 GKVTDLQTQLEELQKK-YQQRLEQEESTKDsvtilelQTQLAQKTTLISDSKLKEQELrEQVHNLEDRL 1904
Cdd:PRK11281   234 ARIQRLEHQLQLLQEAiNSKRLTLSEKTVQ-------EAQSQDEAARIQANPLVAQEL-EINLQLSQRL 294
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 459-704 2.53e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  459 ELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEaELEEQRRHHQREVGSISEQQeltvrraeKALKDELSRLGAL 538
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-ALERRIAALARRIRALEQEL--------AALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  539 LDERDEHLRERQARVQDLEAHLQKSAgelQQALAKLdLLHSEQSAAREQAGAYEEQLAQMQQKVLDLetekslLTKQVVE 618
Cdd:COG4942     92 IAELRAELEAQKEELAELLRALYRLG---RQPPLAL-LLSPEDFLDAVRRLQYLKYLAPARREQAEE------LRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  619 METHKKHVCEELDAQRAQVQQLERQRSELEEKVRSLAQLQdSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILK 698
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLL-ARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*.
gi 1907199025  699 QTLSSK 704
Cdd:COG4942    241 ERTPAA 246
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 348-602 2.59e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 42.63  E-value: 2.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  348 TSLEKSLQESKTQSEHLAVHLEAEKNK-----------------HNKELTA----LAEQHRTEVEGLQQQQDSLWTERLQ 406
Cdd:pfam07902   74 TGLFKSLEEMLSQLKELNLELTDTKNSnlwskiklnnngmlreyHNDTIKTeiveSAEGIATRISEDTDKKLALINETIS 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  407 SLSQQHQAAVEELREKYQQEKDAL---LKEKESLFQAHIQDMNEKTLEKLDKKQMELESVSSELSEAlrARDQLAEELSV 483
Cdd:pfam07902  154 GIRREYQDADRQLSSSYQAGIEGLkatMASDKIGLQAEIQASAQGLSQRYDNEIRKLSAKITTTSSG--TTEAYESKLDD 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  484 LRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKAlkdeLSRLGALLDerdehlrERQARVQDLEahlqKS 563
Cdd:pfam07902  232 LRAEFTRSNQGMRTELESKISGLQSTQQSTAYQISQEISNREGA----VSRVQQDLD-------SYQRRLQDAE----KN 296

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1907199025  564 AGELQQALAKLdllhseQSAAREQAGAYEEQLAQMQ----QKV 602
Cdd:pfam07902  297 YSSLTQTVKGL------QSTVSDPNSKLESRITQLAglieQKV 333
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 111-361 2.71e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  111 CALLLSEKEALQEQLDERLQELEKMKGMvITETKRQMLETLELKEDEIAQLRSHIKQMTTQGEELR--EQKEKSERAAFE 188
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQE-IAELEKELAALKKEEKALLKQLAALERRIAALARRIRalEQELAALEAELA 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  189 ELEKALSTAQKTEDAQRRmkmEMDEQMKAVERASEEERLRLqhelsRVRQEAASMAKKNSE--EQVAALQKLHAEELASK 266
Cdd:COG4942     87 ELEKEIAELRAELEAQKE---ELAELLRALYRLGRQPPLAL-----LLSPEDFLDAVRRLQylKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  267 EQELsRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEELELQKKAiltesENKLQELGQEAEAYRTRILEL 346
Cdd:COG4942    159 LAEL-AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAEL-----AAELAELQQEAEELEALIARL 232

                          250
                   ....*....|....*
gi 1907199025  347 ETSLEKSLQESKTQS 361
Cdd:COG4942    233 EAEAAAAAERTPAAG 247
PRK01156 PRK01156
chromosome segregation protein; Provisional
 567-1154 2.90e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.58  E-value: 2.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  567 LQQALAKLDLLHSEQSAAREQAGAYEEQLAQMQQKVLDLETEKSLLTKQVVEMETHKKHVCEELDAQRAQVQQLERQRSE 646
Cdd:PRK01156   178 LRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  647 LEEKVRSLAQLQDSQLKNSTVEKEqarqsLMEKENIILQMREEQAKEIEILKQTLSSKEESISILheeyetkfKNQEKRM 726
Cdd:PRK01156   258 IKTAESDLSMELEKNNYYKELEER-----HMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNI--------DAEINKY 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  727 EKIKQKAKEMQETKKKLLDQEAKlKKELENTVLELSQKEKQFNAQILEMAQANsagisdtvsRLEENQRQQIESLTGAHQ 806
Cdd:PRK01156   325 HAIIKKLSVLQKDYNDYIKKKSR-YDDLNNQILELEGYEMDYNSYLKSIESLK---------KKIEEYSKNIERMSAFIS 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  807 RKLdDVIEAWEKKLSQQAAELRDKhaeqMEEKEQGLGELRQKVRIVQSEKEELTKEVARLkeavSGQDVA-LAGLQGQLE 885
Cdd:PRK01156   395 EIL-KIQEIDPDAIKKELNEINVK----LQDISSKVSSLNQRIRALRENLDELSRNMEML----NGQSVCpVCGTTLGEE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  886 QKSAVIVSLSERESQLQSQVEKLEADLGcSLSEKLSLQEELAElkLLADKSQLRVSELTGQVQAAEKELQSckslHELSK 965
Cdd:PRK01156   466 KSNHIINHYNEKKSRLEEKIREIEIEVK-DIDEKIVDLKKRKE--YLESEEINKSINEYNKIESARADLED----IKIKI 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  966 KSLEDKSLNLKSLLEELAS----QLDSRCERTKALLEAKTNELVCTSRDKADAILARLSQCQRHTAtvgEALLRRMGQVS 1041
Cdd:PRK01156   539 NELKDKHDKYEEIKNRYKSlkleDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ---EIEIGFPDDKS 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1042 ELEAQLTQLTEEQRTLKSSFqqvtNQLEEKEKQIKTMKADIEGL---LTEKEALQQEGGQQRQAASEKESCITQLKKELA 1118
Cdd:PRK01156   616 YIDKSIREIENEANNLNNKY----NEIQENKILIEKLRGKIDNYkkqIAEIDSIIPDLKEITSRINDIEDNLKKSRKALD 691

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1907199025 1119 ENINAVTLLREELSEKKSEIASLSKQLSDLGAQLES 1154
Cdd:PRK01156   692 DAKANRARLESTIEILRTRINELSDRINDINETLES 727
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1705-1897 4.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 4.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1705 QKLSKEVARLQKELRALRREH------QQELDILKRECEQEAE-EKLKQEQEDLELKHTSTLKQLMREFNTQLAQKEQEL 1777
Cdd:COG3206    185 PELRKELEEAEAALEEFRQKNglvdlsEEAKLLLQQLSELESQlAEARAELAEAEARLAALRAQLGSGPDALPELLQSPV 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1778 ERTVQETIDKAQEVEAELLESHQEET---QQLHRKIAEKEDDLRRTARRYEEILDAREEEMTGKVTDLQTQLEELQKKYQ 1854
Cdd:COG3206    265 IQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLA 344

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1907199025 1855 QRLEQEestkdsVTILELQTQLAQKTTLISD--SKLKEQELREQV 1897
Cdd:COG3206    345 ELPELE------AELRRLEREVEVARELYESllQRLEEARLAEAL 383
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1671-1862 4.48e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1671 EENSQSHEIQSNVGTVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDILKRECEQEAE-----EKLK 1745
Cdd:COG4942     38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEllralYRLG 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1746 QEQEDLELKHTSTLKQ------LMREFNTQLAQKEQELERTVQETIDKAQEVEAE------LLESHQEETQQLHRKIAEK 1813
Cdd:COG4942    118 RQPPLALLLSPEDFLDavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAEraeleaLLAELEEERAALEALKAER 197

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199025 1814 EDDLRRTARRYEEiLDAREEEMTGKVTDLQTQLEELQKKYQQRLEQEES 1862
Cdd:COG4942    198 QKLLARLEKELAE-LAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1324-1467 4.65e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 4.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1324 RDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSSLEAELgtvkkelehvnssvKSRDGELKALEDKLElesa 1403
Cdd:COG2433    390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAEL--------------EEKDERIERLERELS---- 451

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907199025 1404 akvELKRKAEQKIaairkqllsqmeeKTQRYAKDTENRLSELSAQLKEREKQVHSLEDKLKNLE 1467
Cdd:COG2433    452 ---EARSEERREI-------------RKDREISRLDREIERLERELEEERERIEELKRKLERLK 499
PRK12704 PRK12704
phosphodiesterase; Provisional
 255-435 4.72e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 4.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  255 LQKLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQeslaleelelqkkaiLTESENKLQELGQ 334
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKE---------------LRERRNELQKLEK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  335 eaeayrtRILELETSLEKSLQESKTQSEhlavHLEAEKNKHNKELTALAEQhRTEVEGLQQQQDslwtERLQSLSQ--QH 412
Cdd:PRK12704    90 -------RLLQKEENLDRKLELLEKREE----ELEKKEKELEQKQQELEKK-EEELEELIEEQL----QELERISGltAE 153

                          170       180
                   ....*....|....*....|....*.
gi 1907199025  413 QA---AVEELREKYQQEKDALLKEKE 435
Cdd:PRK12704   154 EAkeiLLEKVEEEARHEAAVLIKEIE 179
PLN02939 PLN02939
transferase, transferring glycosyl groups
 658-981 5.04e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  658 QDSQLKN----STVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILH-EEYETKFKNQEKRMEKIKQK 732
Cdd:PLN02939    71 ENGQLENtslrTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQlEDLVGMIQNAEKNILLLNQA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  733 AKEMQETKKKLLDQEAKLKKELENTVLELSQK--------EKQFNAQIL---------EMAQANSAGISDTVSRLEENQR 795
Cdd:PLN02939   151 RLQALEDLEKILTEKEALQGKINILEMRLSETdariklaaQEKIHVEILeeqleklrnELLIRGATEGLCVHSLSKELDV 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  796 QQIESLTgahqrkLDDVIEAWEKKLS--QQAAELRDKHAEQMEEKEQGLGELRQKVRIVQSEKEEL-TKEVARLKEAVSG 872
Cdd:PLN02939   231 LKEENML------LKDDIQFLKAELIevAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLsPLQYDCWWEKVEN 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  873 QDVALAGLQGQLEQKSAVIvslsERESQLQSQVEKLEADLGCSLSEKLSLQeelaelklLADKSQLRVSELTGQVQAAEK 952
Cdd:PLN02939   305 LQDLLDRATNQVEKAALVL----DQNQDLRDKVDKLEASLKEANVSKFSSY--------KVELLQQKLKLLEERLQASDH 372

                          330       340
                   ....*....|....*....|....*....
gi 1907199025  953 ELQSCKSLHELSKKSLEDkslNLKSLLEE 981
Cdd:PLN02939   373 EIHSYIQLYQESIKEFQD---TLSKLKEE 398
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1686-1883 5.45e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 5.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1686 VDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREH------QQELDILKRECE--QEAEEKLKQEQEDLE-LKHT 1756
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyaelQEELEELEEELEelEAELEELREELEKLEkLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1757 STLKQLMREFNTQLAQKEQELER------TVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDA 1830
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEEleerleELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQR 207

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025 1831 REEemtgkvtdLQTQLEELQKKYQQRLEQEESTKDSVTILELQTQLAQKTTLI 1883
Cdd:COG4717    208 LAE--------LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL 252
Rabaptin pfam03528
Rabaptin;
123-498 5.83e-03

Rabaptin;


Pssm-ID: 367545 [Multi-domain]  Cd Length: 486  Bit Score: 41.63  E-value: 5.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  123 EQLDERLQELEKMKGmvitetkrQMLETLELKEDEIAQLRSHIKQMTTQGEELREQKEKSERAAFEELEkalstAQKTED 202
Cdd:pfam03528    4 EDLQQRVAELEKENA--------EFYRLKQQLEAEFNQKRAKFKELYLAKEEDLKRQNAVLQEAQVELD-----ALQNQL 70

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  203 AQRRMKMEmdeQMKAVERASEEerlrlqhelsrVRQEAASMAKKNSEEQVAALQKLHAEELASKEQELSRRLEaRERELQ 282
Cdd:pfam03528   71 ALARAEME---NIKAVATVSEN-----------TKQEAIDEVKSQWQEEVASLQAIMKETVREYEVQFHRRLE-QERAQW 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  283 EQMRIALEKSRSEYLKLTQEKEQQESLaleelelqkkailtesENKLQELGQEAEAYRTRILELETSLeKSLQESKTQSE 362
Cdd:pfam03528  136 NQYRESAEREIADLRRRLSEGQEEENL----------------EDEMKKAQEDAEKLRSVVMPMEKEI-AALKAKLTEAE 198

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  363 HLAVHLEAEKNKHNKELTALAEQHRTEVE---GLQQQQDSLWTERLQSLSQQhqaaVEELREKYQQEKDALLKEKESLFQ 439
Cdd:pfam03528  199 DKIKELEASKMKELNHYLEAEKSCRTDLEmyvAVLNTQKSVLQEDAEKLRKE----LHEVCHLLEQERQQHNQLKHTWQK 274

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907199025  440 AHIQDMNEKTLEKLDKKQMELESVSSELS--EALRARDQLAEELSVLRGDADKMKQALEAE 498
Cdd:pfam03528  275 ANDQFLESQRLLMRDMQRMESVLTSEQLRqvEEIKKKDQEEHKRARTHKEKETLKSDREHT 335
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1608-1921 6.05e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 6.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1608 QEKELTCQALEQRVKELESDLVRERgahrlEVEKLTLKYEKSQSSQQEMDGENKCVEvLEDRPEENSQ--SHEIQSNVGT 1685
Cdd:pfam17380  303 QEKEEKAREVERRRKLEEAEKARQA-----EMDRQAAIYAEQERMAMERERELERIR-QEERKRELERirQEEIAMEISR 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1686 VDGLRSDLESKLTGAERDKQKLskEVARLQKelrALRREHQQELDILKRECEQEAEEKLKQEQEDLELKHTSTLKQLMRE 1765
Cdd:pfam17380  377 MRELERLQMERQQKNERVRQEL--EAARKVK---ILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERV 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1766 FNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEildareeemtGKVTDLQTQ 1845
Cdd:pfam17380  452 RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE----------RKRKLLEKE 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1846 LEELQK---KYQQRLEQEESTKDSVTILE---LQTQLAQKTTLIS--DSKLKEQELREQVHNLEDRLKRYEKNACAATVG 1917
Cdd:pfam17380  522 MEERQKaiyEEERRREAEEERRKQQEMEErrrIQEQMRKATEERSrlEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   ....
gi 1907199025 1918 TPYK 1921
Cdd:pfam17380  602 PIYR 605
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 123-231 6.09e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.61  E-value: 6.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  123 EQLDERLQELEKMKGMVITETKRQMLETLELKEDEIAQLRSHIKQMTTQ-------GEELREQKEKSERAAFE--ELEKA 193
Cdd:COG0542    414 DELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEALKARweaekelIEEIQELKEELEQRYGKipELEKE 493

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1907199025  194 LSTAQKTEDAQRRM-KMEMDEQMKA----------VERASEEERLRLQH 231
Cdd:COG0542    494 LAELEEELAELAPLlREEVTEEDIAevvsrwtgipVGKLLEGEREKLLN 542
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
446-577 6.18e-03

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 41.19  E-value: 6.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  446 NEKTLEKLDKKQMELESVSSELsEALRARDQLAEELSVLRGDADKMKQALE-AELEEQRRHHQREVGSISEQQELTVRRA 524
Cdd:COG1566     78 PTDLQAALAQAEAQLAAAEAQL-ARLEAELGAEAEIAAAEAQLAAAQAQLDlAQRELERYQALYKKGAVSQQELDEARAA 156

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1907199025  525 EKALKDELSRLGALLDERDEHLRErQARVQDLEAHLQKSAGELQQALAKLDLL 577
Cdd:COG1566    157 LDAAQAQLEAAQAQLAQAQAGLRE-EEELAAAQAQVAQAEAALAQAELNLART 208
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 81-677 6.65e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 41.71  E-value: 6.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025   81 KTLEMLQQRVKRQENLLQRCKETigsHKEQCALLLSEKEALQEQLDERLQeLEKMKGMVITETKRQMLETLELKEDEIAQ 160
Cdd:PRK10246   233 KQLLTAQQQQQQSLNWLTRLDEL---QQEASRRQQALQQALAAEEKAQPQ-LAALSLAQPARQLRPHWERIQEQSAALAH 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  161 LRSHIKQMTTQGEELREQKEKSERAAFEELEKALSTAQK------TEDAQRRMKMEMdeqmkAVERASEEERLRLQHELS 234
Cdd:PRK10246   309 TRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSlntwlaEHDRFRQWNNEL-----AGWRAQFSQQTSDREQLR 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  235 RVRQEAASMAKKNSEEQVAALQkLHAEELASKEQELSRRLEARERELQEQMRIALEKSRSEYLKLTQEKEQQESLALEEL 314
Cdd:PRK10246   384 QWQQQLTHAEQKLNALPAITLT-LTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  315 ELQKKAILTESENKLQELGQEAEAyRTRILELEtSLEKSLQESKT-----QSEHLAVH----LEAEKNKH-----NKELT 380
Cdd:PRK10246   463 LNEMRQRYKEKTQQLADVKTICEQ-EARIKDLE-AQRAQLQAGQPcplcgSTSHPAVEayqaLEPGVNQSrldalEKEVK 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  381 ALAEQH---RTEVEGLQQQQDSLwTERLQSLSQQHQAAVEELREKYQQEKDALLKEKESLFQAHIQDMNEKTLEKLDKKQ 457
Cdd:PRK10246   541 KLGEEGaalRGQLDALTKQLQRD-ESEAQSLRQEEQALTQQWQAVCASLNITLQPQDDIQPWLDAQEEHERQLRLLSQRH 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  458 MELESVSSELSEALRARDQLAEELSVLRGDADKMKQALEAELEEQRRHHQREVGSISEQQELTVRRAEKALKDELSRLGA 537
Cdd:PRK10246   620 ELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEASWLATRQQEAQSWQQRQNELTALQNRIQQLTPLLE 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  538 LLDERDEHLRER------------------QARVQDLEAHLQKSAGELQQALAKLD--LLHS--EQSAAREQAGAYEEQL 595
Cdd:PRK10246   700 TLPQSDDLPHSEetvaldnwrqvheqclslHSQLQTLQQQDVLEAQRLQKAQAQFDtaLQASvfDDQQAFLAALLDEETL 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  596 AQMQQKVLDLETE----KSLLTKQVVEMETHKKHVCEELDAQrAQVQQLERQRSELEEKVRSLAQLQD---SQLKNSTvE 668
Cdd:PRK10246   780 TQLEQLKQNLENQrqqaQTLVTQTAQALAQHQQHRPDGLDLT-VTVEQIQQELAQLAQQLRENTTRQGeirQQLKQDA-D 857


                   ....*....
gi 1907199025  669 KEQARQSLM 677
Cdd:PRK10246   858 NRQQQQALM 866
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 853-1077 7.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  853 QSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSEKLSLQEELAELKLL 932
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  933 AdKSQLRVSELTGQvQAAEKELQSCKSLHELSKKSLEDKSLN--LKSLLEELASQLDsRCERTKALLEAKTNELvctsRD 1010
Cdd:COG4942    106 L-AELLRALYRLGR-QPPLALLLSPEDFLDAVRRLQYLKYLApaRREQAEELRADLA-ELAALRAELEAERAEL----EA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907199025 1011 KADAILARLSQCQRHTATVGEALLRRMGQVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKT 1077
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 640-868 7.26e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 7.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  640 LERQRSELEEKVRSL--AQLQDSQLKNSTVEKEQARQSLMEKENIILQMREEQAKEIEILKQTLSSKEESISILHEEYET 717
Cdd:PRK05771    14 LKSYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVEE 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  718 KFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKeLENTVLELsqkekqfnaqILEMAQANSAGISDTVSRLEENQRQQ 797
Cdd:PRK05771    94 ELEKIEKEIKELEEEISELENEIKELEQEIERLEP-WGNFDLDL----------SLLLGFKYVSVFVGTVPEDKLEELKL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  798 IESLTGA---HQRKLDDVIEAW-EKKLSQQAAELRDKH-AEQMEEKEQG-----LGELRQKVRIVQSEKEELTKEVARLK 867
Cdd:PRK05771   163 ESDVENVeyiSTDKGYVYVVVVvLKELSDEVEEELKKLgFERLELEEEGtpselIREIKEELEEIEKERESLLEELKELA 242


                   .
gi 1907199025  868 E 868
Cdd:PRK05771   243 K 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
711-1168 8.56e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.05  E-value: 8.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  711 LHEEYETKfKNQEKRMEKIKQKAKEMQETKKKLLDQEAklkkELENTVLELSQKEKQFNAQILEMAQANSAGISDTVSRL 790
Cdd:COG4913    240 AHEALEDA-REQIELLEPIRELAERYAAARERLAELEY----LRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  791 EENQRQQIESLTGAHQRKLD---DVIEAWEKKLSQQAAELRDK--HAEQMEEKEQGLG--------ELRQKVRIVQSEKE 857
Cdd:COG4913    315 EARLDALREELDELEAQIRGnggDRLEQLEREIERLERELEERerRRARLEALLAALGlplpasaeEFAALRAEAAALLE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  858 ELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQLQSQVEKLEADLgcslSEKLSLQEelAELKLLADKSQ 937
Cdd:COG4913    395 ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL----AEALGLDE--AELPFVGELIE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  938 LRVSELTGQvQAAEKELQSCK------------------SLH----------ELSKKSLEDKSLNLKSLLEELASQLDSR 989
Cdd:COG4913    469 VRPEEERWR-GAIERVLGGFAltllvppehyaaalrwvnRLHlrgrlvyervRTGLPDPERPRLDPDSLAGKLDFKPHPF 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  990 CERTKALLEAKTNELVCTS----RDKADAILArlsQCQ-RHTATVGEALLRRMG------------QVSELEAQLTQLTE 1052
Cdd:COG4913    548 RAWLEAELGRRFDYVCVDSpeelRRHPRAITR---AGQvKGNGTRHEKDDRRRIrsryvlgfdnraKLAALEAELAELEE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1053 EQRTLKSSFQQVTNQLEEKEKQIKTMKA---------DIEGLLTEKEALQqeggQQRQAASEKESCITQLKKELAENINA 1123
Cdd:COG4913    625 ELAEAEERLEALEAELDALQERREALQRlaeyswdeiDVASAEREIAELE----AELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*
gi 1907199025 1124 VTLLREELSEKKSEIASLSKQLSDLGAQLESSISPSDKAEAISAL 1168
Cdd:COG4913    701 LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 642-1467 9.20e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 41.31  E-value: 9.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  642 RQRSELEEKVRSLAQLQDSQLK--NSTVEKEQARQSLMEKENII---LQMREEQAKEIEILKQTLSSKEESISILHEEYE 716
Cdd:pfam01576    2 RQEEEMQAKEEELQKVKERQQKaeSELKELEKKHQQLCEEKNALqeqLQAETELCAEAEEMRARLAARKQELEEILHELE 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  717 TKFKNQEKRMEKIKQKAKEMQETKKKL---LDQEAKLKKELENTVLELSQKEKQFNAQILEMAQANSA----------GI 783
Cdd:pfam01576   82 SRLEEEEERSQQLQNEKKKMQQHIQDLeeqLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKlskerklleeRI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  784 SDTVSRL--EENQRQQIESLTGAHQRKLDDV-------------IEAWEKKLSQQAAELRDKHAEQMEEKEQGLGELRQK 848
Cdd:pfam01576  162 SEFTSNLaeEEEKAKSLSKLKNKHEAMISDLeerlkkeekgrqeLEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  849 vrivqseKEELTKEVARLKEAVSGQDVALAGLQgQLEQKSAVIVSLSERESQLQSQVEKLEADLGCSLSeklSLQEELAE 928
Cdd:pfam01576  242 -------EEELQAALARLEEETAQKNNALKKIR-ELEAQISELQEDLESERAARNKAEKQRRDLGEELE---ALKTELED 310

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  929 LKLLADKSQLRVSELTGQVQAAEKELQSCKSLHELSKKSLEDKSlnlKSLLEELASQLD------SRCERTKALLEAKTN 1002
Cdd:pfam01576  311 TLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKH---TQALEELTEQLEqakrnkANLEKAKQALESENA 387

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1003 ELVCTSRDKADAILARLSQCQRHTATVGEALLRrmgqVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKE-KQIKTMK-- 1079
Cdd:pfam01576  388 ELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR----LSESERQRAELAEKLSKLQSELESVSSLLNEAEgKNIKLSKdv 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1080 ADIEGLLTEKEALQQEGGQQRQAASEK----ESCITQLKKELAENINAVTLLREELSEKKSEIASLSKQLSDLGAQLESS 1155
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1156 ISPSDKAEAISALSKQHEEQELQLQAQLQELSLKVDALSKEKMSALEQVDHWSNKFSEWKKKAQSRLAQHQSTIKDLQAQ 1235
Cdd:pfam01576  544 EEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1236 LDVKATDAREKE----------EQICLLKEDLDRQNKKfecLKGEMEVRKS----------KMEKKECDLETALKTQTAR 1295
Cdd:pfam01576  624 RDRAEAEAREKEtralslaralEEALEAKEELERTNKQ---LRAEMEDLVSskddvgknvhELERSKRALEQQVEEMKTQ 700

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1296 VVELEDCVTQRKKEVESLNETLKNYNQQRDTEhsglvqrLQHLEELGEEKDNKvreaeetvlrLREHVSSLEAELGTVKK 1375
Cdd:pfam01576  701 LEELEDELQATEDAKLRLEVNMQALKAQFERD-------LQARDEQGEEKRRQ----------LVKQVRELEAELEDERK 763

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1376 ELEHVNSSVKSRDGELKALEDKLELESAAKVELKRKAeqkiaairKQLLSQMEEkTQRYAKDTENRLSELSAQLKEREKQ 1455
Cdd:pfam01576  764 QRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQL--------KKLQAQMKD-LQRELEEARASRDEILAQSKESEKK 834

                          890
                   ....*....|..
gi 1907199025 1456 VHSLEDKLKNLE 1467
Cdd:pfam01576  835 LKNLEAELLQLQ 846
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1687-1797 9.33e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 40.39  E-value: 9.33e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  1687 DGLRSDLESKLTGAERDKQKLSKE-------VARLQKELRALRREHQQeLDILKRECEQEAEEKLKQEQEDLElkhtSTL 1759
Cdd:smart00787  143 EGLKEGLDENLEGLKEDYKLLMKElellnsiKPKLRDRKDALEEELRQ-LKQLEDELEDCDPTELDRAKEKLK----KLL 217

                            90       100       110       120
                    ....*....|....*....|....*....|....*....|
gi 1907199025  1760 KQLMREFN--TQLAQKEQELERTVQETIDKAQEVEAELLE 1797
Cdd:smart00787  218 QEIMIKVKklEELEEELQELESKIEDLTNKKSELNTEIAE 257
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 679-901 9.49e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 9.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  679 KENIIlqmreEQAKEIeilkqtLSSKEESISILHEEYETKFKNQEKRMEKIKQKAKEMQETKKKLLDQEAKLKKELENTV 758
Cdd:PRK00409   500 PENII-----EEAKKL------IGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLL 568

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  759 LELSQKEKqfnaQILEMAQANSAGIsdtVSRLEENQRQQIESLtgahqrKLDDVIEAweKKLSQQAAELRDKHAEQMEEK 838
Cdd:PRK00409   569 EEAEKEAQ----QAIKEAKKEADEI---IKELRQLQKGGYASV------KAHELIEA--RKRLNKANEKKEKKKKKQKEK 633

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907199025  839 EQGL--GE------LRQKVRIVQ-SEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIVSLSERESQL 901
Cdd:PRK00409   634 QEELkvGDevkylsLGQKGEVLSiPDDKEAIVQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTVSL 705
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1039-1154 9.56e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.77  E-value: 9.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1039 QVSELEAQLTQLTEEQRTLKSSFQQVTNQLEEKEKQIKTMKAD--IEGLLTEKEALQQEGGQQRQAASEKESCITQLKKE 1116
Cdd:COG3206    220 QLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQ 299

                           90       100       110
                   ....*....|....*....|....*....|....*....
gi 1907199025 1117 LAENINAV-TLLREELSEKKSEIASLSKQLSDLGAQLES 1154
Cdd:COG3206    300 IAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQ 338
PRK11281 PRK11281
mechanosensitive channel MscK;
739-1157 9.61e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.05  E-value: 9.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  739 TKKKLLDQEAKL-KKELENTVLELSQKEKQfnaqilemaqansagisdtvsrleenqRQQIESLtgahqrklddvieawE 817
Cdd:PRK11281    49 NKQKLLEAEDKLvQQDLEQTLALLDKIDRQ---------------------------KEETEQL---------------K 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  818 KKLSQQAAELRDKHAEQMEEKEQGLGELRQK-----VRIVQSEKEELTKEVARLKEAVSGQDVALAGLQGQLEQKSAVIV 892
Cdd:PRK11281    87 QQLAQAPAKLRQAQAELEALKDDNDEETRETlstlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  893 SLSERESQLQSQVEKLEAD-LGCSLSEKLSLQEELAEL--------KLLADKSQL------RVSELTGQVQAAEKELQ-- 955
Cdd:PRK11281   167 ANSQRLQQIRNLLKGGKVGgKALRPSQRVLLQAEQALLnaqndlqrKSLEGNTQLqdllqkQRDYLTARIQRLEHQLQll 246

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  956 ----SCKSLHELSKKSLEDKSLNLKSLLEE---LASQLDSRCERTKALLEA--KTNELvctSRD--KADAILARLSQCQR 1024
Cdd:PRK11281   247 qeaiNSKRLTLSEKTVQEAQSQDEAARIQAnplVAQELEINLQLSQRLLKAteKLNTL---TQQnlRVKNWLDRLTQSER 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1025 HtatvgeallrrmgqvseLEAQLTQLteeQRTLKSS---FQQvtNQLEEKEKQIKTMKADIEGLLTEkealQQEGGQQRQ 1101
Cdd:PRK11281   324 N-----------------IKEQISVL---KGSLLLSrilYQQ--QQALPSADLIEGLADRIADLRLE----QFEINQQRD 377

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907199025 1102 AASEKESCITQLKKELAENINAVTL--LREELSEKKSEIASLSKQlsdLGAQLESSIS 1157
Cdd:PRK11281   378 ALFQPDAYIDKLEAGHKSEVTDEVRdaLLQLLDERRELLDQLNKQ---LNNQLNLAIN 432
mukB PRK04863
chromosome partition protein MukB;
340-776 9.78e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.10  E-value: 9.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  340 RTRILELETSLEKSLQESKTQ---SEHLAVHLEAEKNKHNKELTALAEQHRTEVEGLQQQQDSLwteRLQSLSQQHQAAV 416
Cdd:PRK04863   281 RRVHLEEALELRRELYTSRRQlaaEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTAL---RQQEKIERYQADL 357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  417 EELREKYQQEKDALLKEKEslfqahIQDMNEktlEKLDKKQMELESVSSELSEALRARDqlaeelsVLRGDADKMKQALE 496
Cdd:PRK04863   358 EELEERLEEQNEVVEEADE------QQEENE---ARAEAAEEEVDELKSQLADYQQALD-------VQQTRAIQYQQAVQ 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  497 AeLEEQRrhhqrevgSISEQQELTVrraeKALKDELSRLGALLDERDEHLRERQARVQDLEAHLQKSAGELQQALAKLDL 576
Cdd:PRK04863   422 A-LERAK--------QLCGLPDLTA----DNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGE 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  577 LHSEQ--SAAREQAGAYEEQLAQMQQkvldletekslltkqVVEMETHKKHVCEELDAQRAQVQQLER--QRSEL----E 648
Cdd:PRK04863   489 VSRSEawDVARELLRRLREQRHLAEQ---------------LQQLRMRLSELEQRLRQQQRAERLLAEfcKRLGKnlddE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025  649 EKVRSLAQLQDSQLKNSTVEKEQARQSLMEKENIILQMReEQAKEIEILKQTLSSKEESISILHEEYETKFKNQEKRMEK 728
Cdd:PRK04863   554 DELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQ-ARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEY 632

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1907199025  729 IKQKAKEMQETKKKlLDQEAKLKKELENTVLELSQKEKQFNAQILEMA 776
Cdd:PRK04863   633 MQQLLERERELTVE-RDELAARKQALDEEIERLSQPGGSEDPRLNALA 679
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1213-1849 9.97e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.11  E-value: 9.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1213 EWKKKAQSRLAQHQSTIKDLQAQLDV-----KATDAREKEEQICLLKEDLDRQNKKFECLKGEMEVRKSKMEKKECDLET 1287
Cdd:TIGR00618  253 EEQLKKQQLLKQLRARIEELRAQEAVleetqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1288 ALKTQ--TARVVELEDCVTQRKKEVESLNETLKNYNQQRDTEHSgLVQRLQHLEELGEEKDNKVREAEETVLRLREHVSS 1365
Cdd:TIGR00618  333 HVKQQssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQREQAT 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1366 LEAELGTVKKELEHVNSSvksrDGELKALEDKLELESAAKVELKRKAEQKIAAIRKQLLSQMEEKTQRYAKDTENRLSEL 1445
Cdd:TIGR00618  412 IDTRTSAFRDLQGQLAHA----KKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR 487

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1446 SAQLKEREKQVHSLEDKLKNlESSPHPEVPAVSRSMQSVAASPEQEAPDsqdcTHKACKERLCMLQRRLSEKEKLLRRLE 1525
Cdd:TIGR00618  488 KKAVVLARLLELQEEPCPLC-GSCIHPNPARQDIDNPGPLTRRMQRGEQ----TYAQLETSEEDVYHQLTSERKQRASLK 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1526 QGEGEARPSQPEAQHRALSGKLDCTRARQLEDHVL-IGCLPEELEEKMKCSLIVSQPMGEETGNNTGVKQNWASVVDSVQ 1604
Cdd:TIGR00618  563 EQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQdLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1605 KTLQEKELTCQALEQRVKELESDLVRERGAHRLEVEKLTLKYEKSQSSQQEMDgenkcvevLEDRPEENSQSHEIQSNVG 1684
Cdd:TIGR00618  643 LKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW--------KEMLAQCQTLLRELETHIE 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1685 TVDGLRSDLESKLTGAERDKQKLSKEVARLQKELRALRREHQQELDIlkrECEQEAEEKLKQEQEDLELKHTSTLKQLMR 1764
Cdd:TIGR00618  715 EYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTE---AHFNNNEEVTAALQTGAELSHLAAEIQFFN 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907199025 1765 EFNTQLAQKEQELERTVQETIDKAQEVEAELLESHQEETQQLHRKIAEKEDDLRRTARRYEEILDARE--EEMTGKVTDL 1842
Cdd:TIGR00618  792 RLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKqlAQLTQEQAKI 871


                   ....*..
gi 1907199025 1843 QTQLEEL 1849
Cdd:TIGR00618  872 IQLSDKL 878
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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