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Conserved domains on  [gi|1907082938|ref|XP_036012842|]
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UPF0450 protein C17orf58 homolog isoform X8 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NTR_like super family cl02512
NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in ...
 172-353 1.27e-17

NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the domain plays a role in controlling axon branching in neural development, while the common function of these modules in TIMPs appears to be binding to metzincins. A subset of this family is also known as the C345C domain because it occurs as a C-terminal domain in complement C3, C4 and C5. In C5, the domain interacts with various partners during the formation of the membrane attack complex.


The actual alignment was detected with superfamily member cd03576:

Pssm-ID: 470599  Cd Length: 124  Bit Score: 78.20  E-value: 1.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 172 PETQSCARACSADADEWEAYCASEFAaVNGIVHDVDVLGAGMRLVTLLvdpDGLYKMSRLYITPDGFFFRVHILALDsss 251
Cdd:cd03576     1 PTAALCQQKCRRTGTLESNYCSSEFV-ITGTVISMTRGPGSLHATVSI---IKLYKEGRLAITQAGKTMSVKITVVC--- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 252 chKPCPEFKpgieipspekaihrvlynatgdlsaaaqlllvtpapnslfkdqalsrashtPGSRYIVMGHIYH-KRRQLP 330
Cdd:cd03576    74 --KQCPLLR---------------------------------------------------RGLNYILMGQVDEeGRGVIP 100

                         170       180
                  ....*....|....*....|...
gi 1907082938 331 SAllQVLRGRLRPGDGLIRGSSS 353
Cdd:cd03576   101 PE--SFVMLYKTKHQKLLAALSN 121
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 45-167 7.20e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 7.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   45 PPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTA---PPADNRAGFRDAVHAPAALPGPR--LAQAEN 119
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatPGGPARPARPPTTAGPPAPAPPAapAAGPPR 2781

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1907082938  120 RASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
 
Name Accession Description Interval E-value
NTR_PCOLCE cd03576
NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are ...
 172-353 1.27e-17

NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are extracellular matrix proteins that enhance the activity of procollagen C-proteases, by binding to the procollagen I C-peptide. They contain a C-terminal NTR domain, which have been suggested to possess inhibitory functions towards specific serine proteases but not towards metzincins, which are inhibited by the related TIMPs.


Pssm-ID: 239631  Cd Length: 124  Bit Score: 78.20  E-value: 1.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 172 PETQSCARACSADADEWEAYCASEFAaVNGIVHDVDVLGAGMRLVTLLvdpDGLYKMSRLYITPDGFFFRVHILALDsss 251
Cdd:cd03576     1 PTAALCQQKCRRTGTLESNYCSSEFV-ITGTVISMTRGPGSLHATVSI---IKLYKEGRLAITQAGKTMSVKITVVC--- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 252 chKPCPEFKpgieipspekaihrvlynatgdlsaaaqlllvtpapnslfkdqalsrashtPGSRYIVMGHIYH-KRRQLP 330
Cdd:cd03576    74 --KQCPLLR---------------------------------------------------RGLNYILMGQVDEeGRGVIP 100

                         170       180
                  ....*....|....*....|...
gi 1907082938 331 SAllQVLRGRLRPGDGLIRGSSS 353
Cdd:cd03576   101 PE--SFVMLYKTKHQKLLAALSN 121
PHA03247 PHA03247
large tegument protein UL36; Provisional
 45-167 7.20e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 7.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   45 PPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTA---PPADNRAGFRDAVHAPAALPGPR--LAQAEN 119
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatPGGPARPARPPTTAGPPAPAPPAapAAGPPR 2781

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1907082938  120 RASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
 
Name Accession Description Interval E-value
NTR_PCOLCE cd03576
NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are ...
 172-353 1.27e-17

NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are extracellular matrix proteins that enhance the activity of procollagen C-proteases, by binding to the procollagen I C-peptide. They contain a C-terminal NTR domain, which have been suggested to possess inhibitory functions towards specific serine proteases but not towards metzincins, which are inhibited by the related TIMPs.


Pssm-ID: 239631  Cd Length: 124  Bit Score: 78.20  E-value: 1.27e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 172 PETQSCARACSADADEWEAYCASEFAaVNGIVHDVDVLGAGMRLVTLLvdpDGLYKMSRLYITPDGFFFRVHILALDsss 251
Cdd:cd03576     1 PTAALCQQKCRRTGTLESNYCSSEFV-ITGTVISMTRGPGSLHATVSI---IKLYKEGRLAITQAGKTMSVKITVVC--- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 252 chKPCPEFKpgieipspekaihrvlynatgdlsaaaqlllvtpapnslfkdqalsrashtPGSRYIVMGHIYH-KRRQLP 330
Cdd:cd03576    74 --KQCPLLR---------------------------------------------------RGLNYILMGQVDEeGRGVIP 100

                         170       180
                  ....*....|....*....|...
gi 1907082938 331 SAllQVLRGRLRPGDGLIRGSSS 353
Cdd:cd03576   101 PE--SFVMLYKTKHQKLLAALSN 121
PHA03247 PHA03247
large tegument protein UL36; Provisional
 45-167 7.20e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 7.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   45 PPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTA---PPADNRAGFRDAVHAPAALPGPR--LAQAEN 119
Cdd:PHA03247  2702 PPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatPGGPARPARPPTTAGPPAPAPPAapAAGPPR 2781

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1907082938  120 RASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2782 RLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
71-189 7.69e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 47.95  E-value: 7.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  71 PRAAYAGPRAWPDPRRR--KTAPPADNRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAH 148
Cdd:PRK12323  374 PATAAAAPVAQPAPAAAapAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPA 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1907082938 149 P------NRPRAAAQPSGTPQALSPEDREPETQSCARACSADADEWE 189
Cdd:PRK12323  454 PaaapaaAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWE 500
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
17-201 1.70e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.79  E-value: 1.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  17 PEAPVAERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPADNR 96
Cdd:PRK12323  404 AAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA 483

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  97 AGFRDAVHAPAALPGPRLAQAENRASPPEDS---PRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDREPE 173
Cdd:PRK12323  484 APAAAPAPADDDPPPWEELPPEFASPAPAQPdaaPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAP 563

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1907082938 174 T---QSCARACSADADEWEAYCA--------------SEFAAVNG 201
Cdd:PRK12323  564 RpprASASGLPDMFDGDWPALAArlpvrglaqqlarqSELAGVEG 608
PHA03247 PHA03247
large tegument protein UL36; Provisional
 42-182 1.87e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 1.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   42 EPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAG---PRAWPDPRRRKTAPpadnragfrdavhAPAALPGPRLAQAE 118
Cdd:PHA03247  2604 DRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDphpPPTVPPPERPRDDP-------------APGRVSRPRRARRL 2670

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907082938  119 NRASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSgtPQALSPEDREPETQSCARACS 182
Cdd:PHA03247  2671 GRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPA--PHALVSATPLPPGPAAARQAS 2732
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 16-190 2.75e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 2.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  16 SPEAPVAERKAfSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPrrrkTAPPADN 95
Cdd:PRK07764  620 APAAPAAPAPA-GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP----AAPAAPA 694

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  96 RAGFRDAVHAPAALPGPRLAQAENRASPP----EDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDRE 171
Cdd:PRK07764  695 GAAPAQPAPAPAATPPAGQADDPAAQPPQaaqgASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAP 774

                         170
                  ....*....|....*....
gi 1907082938 172 PETQSCARACSADADEWEA 190
Cdd:PRK07764  775 PPSPPSEEEEMAEDDAPSM 793
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
30-198 2.86e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 2.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  30 GKTGSAAEMISCEPAP---------PPHRKPDSRETPGPRAQPLPEFSRRPR--AAYAGPRAWPDPR--------RRKTA 90
Cdd:PRK07003  347 GFTMTLLRMLAFEPAVtgggapgggVPARVAGAVPAPGARAAAAVGASAVPAvtAVTGAAGAALAPKaaaaaaatRAEAP 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  91 PPADNRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDR 170
Cdd:PRK07003  427 PAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAA 506

                         170       180
                  ....*....|....*....|....*...
gi 1907082938 171 EPETQSCARACSADADEWEAYCASEFAA 198
Cdd:PRK07003  507 VPDARAPAAASREDAPAAAAPPAPEARP 534
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 19-190 8.70e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.59  E-value: 8.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  19 APVAERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPADNRAG 98
Cdd:PRK07764  591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  99 FRDAVHAPAALPG---PRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDREPETQ 175
Cdd:PRK07764  671 AKAGGAAPAAPPPapaPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPD 750

                         170
                  ....*....|....*
gi 1907082938 176 SCARACSADADEWEA 190
Cdd:PRK07764  751 PAGAPAQPPPPPAPA 765
PHA03247 PHA03247
large tegument protein UL36; Provisional
 43-160 8.89e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 8.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   43 PAPPPHRKPDSRETPGPRAQPLPEFSRRP--RAAYAGPRAWPDPRRRKTAPPADNRAGFRDAVhAPAALPGPRLAQAENR 120
Cdd:PHA03247  2838 APPPPPGPPPPSLPLGGSVAPGGDVRRRPpsRSPAAKPAAPARPPVRRLARPAVSRSTESFAL-PPDQPERPPQPQAPPP 2916

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1907082938  121 ASPPEDSPRRALSRAVRPPGARAASPAHPN-RPRAAAQPSG 160
Cdd:PHA03247  2917 PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTtDPAGAGEPSG 2957
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
16-165 1.00e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.46  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  16 SPEAPVAERKAFSEGKTGSAAEMISCEPAPPPHRKP---DSRETPGPRAQPLPefSRRPRAAYAGPRAWPDPR------- 85
Cdd:PRK07003  396 VPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAppaTADRGDDAADGDAP--VPAKANARASADSRCDERdaqppad 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  86 -RRKTAPPADNRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAhPNRPRAAAQPSGTPQA 164
Cdd:PRK07003  474 sGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPT-PAAAAPAARAGGAAAA 552


                  .
gi 1907082938 165 L 165
Cdd:PRK07003  553 L 553
PHA03247 PHA03247
large tegument protein UL36; Provisional
 16-167 1.48e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.16  E-value: 1.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   16 SPEAPVAERKAFSEGKTGSAAEMISCEPAPPP-HRKPDSRETPGPRAQPLPEfSRRPRAAYAGPRAWPD----------- 83
Cdd:PHA03247  2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPpSPSPAANEPDPHPPPTVPP-PERPRDDPAPGRVSRPrrarrlgraaq 2675

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   84 -------PRRRKTAPPADNRAGFRD--------------AVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPG-- 140
Cdd:PHA03247  2676 assppqrPRRRAARPTVGSLTSLADpppppptpepaphaLVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGpa 2755

                          170       180
                   ....*....|....*....|....*....
gi 1907082938  141 --ARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2756 rpARPPTTAGPPAPAPPAAPAAGPPRRLT 2784
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
22-174 1.88e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 1.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  22 AERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRrktaPPAdnRAGFRD 101
Cdd:PRK12323  362 AFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARR----SPA--PEALAA 435

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907082938 102 AVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPgarAASPAHPNRPRAAAQPSGTPQALSPEDREPET 174
Cdd:PRK12323  436 ARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVA---AAAAAAPARAAPAAAPAPADDDPPPWEELPPE 505
PHA03378 PHA03378
EBNA-3B; Provisional
 31-165 2.70e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.13  E-value: 2.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  31 KTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRawpdprrrktaPPADNRAGFRDAVHAPAALP 110
Cdd:PHA03378  677 SPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRAR-----------PPAAAPGRARPPAAAPGRAR 745

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938 111 GPrlAQAENRASPPEDSPRRALSRAVRPPGAR-----AASPAHPNRPRAAAQPSGTPQAL 165
Cdd:PHA03378  746 PP--AAAPGRARPPAAAPGRARPPAAAPGAPTpqpppQAPPAPQQRPRGAPTPQPPPQAG 803
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 18-173 5.27e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 5.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  18 EAPVAERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETP---GPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPAD 94
Cdd:PRK07764  371 ERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPapaAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPA 450

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907082938  95 NRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRralsravrppgARAASPAHPNRPRAAAQPSGTPQALSPEDREPE 173
Cdd:PRK07764  451 GGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPP-----------AAPAPAAAPAAPAAPAAPAGADDAATLRERWPE 518
PHA03247 PHA03247
large tegument protein UL36; Provisional
 44-175 6.32e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 6.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   44 APPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWpDPRRRKTAPPADNRAGFRDAVHAPAALPGPRLAQAENRASP 123
Cdd:PHA03247  2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPW-DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPP 2843

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907082938  124 PEDSPRRALSRAVRP---------PGARAASPAHPNRPRA------AAQPSGTPQALSPEDREPETQ 175
Cdd:PHA03247  2844 GPPPPSLPLGGSVAPggdvrrrppSRSPAAKPAAPARPPVrrlarpAVSRSTESFALPPDQPERPPQ 2910
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 14-147 7.66e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 7.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  14 GWSPEAPVAERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPA 93
Cdd:PRK07764  668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDD 747

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1907082938  94 DNRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPA 147
Cdd:PRK07764  748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDA 801
PHA03247 PHA03247
large tegument protein UL36; Provisional
 43-172 7.71e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 7.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   43 PAPPPHRKPD-------SRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPP-------ADNRAGFRDAVHAPAA 108
Cdd:PHA03247  2475 PGAPVYRRPAearfpfaAGAAPDPGGGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPrmltwirGLEELASDDAGDPPPP 2554

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907082938  109 LPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDREP 172
Cdd:PHA03247  2555 LPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLP 2618
PHA03247 PHA03247
large tegument protein UL36; Provisional
 43-182 8.34e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 8.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   43 PAPPPHRKPDSRETPGPRAQP-------------LPEFSRRPRAayagPRAWPDPRRRKTA------------PPADNRA 97
Cdd:PHA03247  2557 PAAPPAAPDRSVPPPRPAPRPsepavtsrarrpdAPPQSARPRA----PVDDRGDPRGPAPpsplppdthapdPPPPSPS 2632

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   98 GFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPgaRAASPAHPNRPRAAAQPSGTPQALS-PEDREPETQS 176
Cdd:PHA03247  2633 PAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAA--QASSPPQRPRRRAARPTVGSLTSLAdPPPPPPTPEP 2710


                   ....*.
gi 1907082938  177 CARACS 182
Cdd:PHA03247  2711 APHALV 2716
PHA03247 PHA03247
large tegument protein UL36; Provisional
 49-178 1.02e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   49 RKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPADNRAGfrdAVHAPAALPGPRLAQAENRASPPEDSP 128
Cdd:PHA03247  2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA---TPGGPARPARPPTTAGPPAPAPPAAPA 2776

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1907082938  129 RRALSRAVRPPGArAASPAHPNRPRAAAQPSGTPQALSPEDREPETQSCA 178
Cdd:PHA03247  2777 AGPPRRLTRPAVA-SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA 2825
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 61-180 1.13e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  61 AQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPADNRAGFRDAVHAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPG 140
Cdd:PRK07764  375 LARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP 454

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1907082938 141 ARAASPAHPNRPRAAAQPSGTPQALSPEDREPETQSCARA 180
Cdd:PRK07764  455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAP 494
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 16-179 1.49e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 40.50  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  16 SPEAPVAER----KAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAP 91
Cdd:PRK14965  362 APGAPVSELldrlEALERGAPAPPSAAWGAPTPAAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPA 441

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  92 PADNRA-GFRDAVhAPAALPGPRLAQAENRASP------------PEDS--------PRR-----ALSRAV--RPPGARA 143
Cdd:PRK14965  442 AAASAGdRWRAFV-AFVKGKKPALGASLEQGSPlgvsaglleigfPEGSfelsamqdPDSraelkALAEQFfgRPTRLRI 520

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907082938 144 ASpahpnrprAAAQPSGTPQALSPEDREPETQSCAR 179
Cdd:PRK14965  521 TV--------LAAPPGAAPPSLAEKKAAEREQRQAR 548
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 31-160 2.03e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.08  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  31 KTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAWPDPRRRKTAPPAdnragfRDAVHAPAALP 110
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVA------APAAAAPAAAP 438

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907082938 111 GPRLAQAENRASPPEDSPRRALSRAVR------PPGARAASPAHPNRPRAAAQPSG 160
Cdd:PRK14951  439 AAAPAAVALAPAPPAQAAPETVAIPVRvapepaVASAAPAPAAAPAAARLTPTEEG 494
dnaA PRK14086
chromosomal replication initiator protein DnaA;
42-189 2.48e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 39.81  E-value: 2.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  42 EPAPPPhrkPDSRETPGPRaqpLPEFSRRPRAAYAGPRAWPdprRRKTAPPADNRagfrdavhaPAALPGprlAQAENRA 121
Cdd:PRK14086   94 EPAPPP---PHARRTSEPE---LPRPGRRPYEGYGGPRADD---RPPGLPRQDQL---------PTARPA---YPAYQQR 152

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907082938 122 SPPEDSPRRALSRAVRPPGArAASPAHPNRPRAAAQPSGTPQALSPEDREPETQSCARACSADADEWE 189
Cdd:PRK14086  153 PEPGAWPRAADDYGWQQQRL-GFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWD 219
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 70-190 2.77e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.97  E-value: 2.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  70 RPRAAYAGPRAWPDPRR-RKTAPPADNRAGFRDAVHAPAALPGPRLAQAENRASPPEdSPRRALSRAVRPPGARAASPAH 148
Cdd:PRK07764  398 APSAAAAAPAAAPAPAAaAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP-SPPPAAAPSAQPAPAPAAAPEP 476

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1907082938 149 PNRPRAAAQPSGTPQALSPEDREPETQSCARACSADADEWEA 190
Cdd:PRK07764  477 TAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPE 518
flhF PRK06995
flagellar biosynthesis protein FlhF;
71-180 2.83e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 39.56  E-value: 2.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  71 PRAAYAGPRAWPDPRrrkTAPPADNRAGfrdavhAPAALPGPRLAQAENRASPPEDSPRRALSRAVRPPGARAASPAHPN 150
Cdd:PRK06995   53 PPAAAAPAAAQPPPA---AAPAAVSRPA------APAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERA 123

                          90       100       110
                  ....*....|....*....|....*....|
gi 1907082938 151 RPRAAAQPSGTPQALSPEDREPETQSCARA 180
Cdd:PRK06995  124 AAENAARRLARAAAAAPRPRVPADAAAAVA 153
PHA03247 PHA03247
large tegument protein UL36; Provisional
 42-167 3.12e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   42 EPAPPPHRKPDSRETPGP-------RAQPLPEFSRRPRAAYAGPrAWPDPRRRKTAPPADNRAGFRDAVHAPAALPGPRL 114
Cdd:PHA03247  2705 PPTPEPAPHALVSATPLPpgpaaarQASPALPAAPAPPAVPAGP-ATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRL 2783

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907082938  115 ---------AQAENRASPPEDSPRRALSRAVRPPGARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2784 trpavaslsESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGP 2845
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 19-188 4.21e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.08  E-value: 4.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  19 APVAERKAFSEGKTGSAAEMISCEPAPPPHRKPDSRETPGPRAQPLPEfSRRPRAAYAGPRAWPDPRRRKTAPPADNRAG 98
Cdd:PRK07994  367 EPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVP-LPETTSQLLAARQQLQRAQGATKAKKSEPAA 445

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  99 FRDAVHAPAALPgpRLAQAENRASPPEDSPrralsrAVRPPGARAASPAHPNRPRAAAQPSGTPQALSPEDrEPETQSCA 178
Cdd:PRK07994  446 ASRARPVNSALE--RLASVRPAPSALEKAP------AKKEAYRWKATNPVEVKKEPVATPKALKKALEHEK-TPELAAKL 516

                         170
                  ....*....|
gi 1907082938 179 RACSADADEW 188
Cdd:PRK07994  517 AAEAIERDPW 526
PHA03247 PHA03247
large tegument protein UL36; Provisional
 45-167 5.91e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.77  E-value: 5.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938   45 PPPHRKPDSRETPGPRAQPLPEFSRRPRAAYAGPRAwpdprRRKTAPPADNRAgfrdavHAPAALPGPRLAQAENRASPP 124
Cdd:PHA03247  2551 PPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRA-----RRPDAPPQSARP------RAPVDDRGDPRGPAPPSPLPP 2619

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1907082938  125 EDSPRRAlsravrPPGARAASPAHPNRPRAAAQPSGTPQALSP 167
Cdd:PHA03247  2620 DTHAPDP------PPPSPSPAANEPDPHPPPTVPPPERPRDDP 2656
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 42-164 9.17e-03

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 38.17  E-value: 9.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907082938  42 EPAPPPHRKpdSRETPGPRAQPLPEFSRRPRAAYAgprawPDPRRRKTAPPADnrAGFRDAVHAPAALPGPRLAQAE--N 119
Cdd:PHA03269   41 DPAPAPHQA--ASRAPDPAVAPTSAASRKPDLAQA-----PTPAASEKFDPAP--APHQAASRAPDPAVAPQLAAAPkpD 111

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1907082938 120 RASPPEDSPRRalsravRPPGARAASPAHPNRPRAAAQPSGTPQA 164
Cdd:PHA03269  112 AAEAFTSAAQA------HEAPADAGTSAASKKPDPAAHTQHSPPP 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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