interleukin-3 receptor subunit alpha isoform X10 [Mus musculus]
List of domain hits
Name | Accession | Description | Interval | E-value | ||
FN3 super family | cl21522 | Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
237-272 | 3.67e-09 | ||
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases. The actual alignment was detected with superfamily member pfam09240: Pssm-ID: 473895 Cd Length: 96 Bit Score: 53.57 E-value: 3.67e-09
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IL3Ra_N super family | cl39930 | IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell ... |
149-209 | 2.78e-03 | ||
IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Structure of IL-3 receptor alpha chain (IL3Ra) in complex with the anti-leukemia antibody CSL362 reveals that the N-terminal domain (NTD), a domain also present in the granulocyte-macrophage colony-stimulating factor (GM-CSF), contains the CSL362 binding epitope. Furthermore, NTD of IL3Ra adopts a typical fibronectin type III (FnIII) fold. The actual alignment was detected with superfamily member pfam18611: Pssm-ID: 436618 Cd Length: 76 Bit Score: 36.56 E-value: 2.78e-03
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Name | Accession | Description | Interval | E-value | ||
IL6Ra-bind | pfam09240 | Interleukin-6 receptor alpha chain, binding; Members of this family adopt a structure ... |
237-272 | 3.67e-09 | ||
Interleukin-6 receptor alpha chain, binding; Members of this family adopt a structure consisting of an immunoglobulin-like beta-sandwich, with seven strands in two beta-sheets, in a Greek-key topology. They are required for binding to the cytokine Interleukin-6. Pssm-ID: 401252 Cd Length: 96 Bit Score: 53.57 E-value: 3.67e-09
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IL3Ra_N | pfam18611 | IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell ... |
149-209 | 2.78e-03 | ||
IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Structure of IL-3 receptor alpha chain (IL3Ra) in complex with the anti-leukemia antibody CSL362 reveals that the N-terminal domain (NTD), a domain also present in the granulocyte-macrophage colony-stimulating factor (GM-CSF), contains the CSL362 binding epitope. Furthermore, NTD of IL3Ra adopts a typical fibronectin type III (FnIII) fold. Pssm-ID: 436618 Cd Length: 76 Bit Score: 36.56 E-value: 2.78e-03
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Name | Accession | Description | Interval | E-value | ||
IL6Ra-bind | pfam09240 | Interleukin-6 receptor alpha chain, binding; Members of this family adopt a structure ... |
237-272 | 3.67e-09 | ||
Interleukin-6 receptor alpha chain, binding; Members of this family adopt a structure consisting of an immunoglobulin-like beta-sandwich, with seven strands in two beta-sheets, in a Greek-key topology. They are required for binding to the cytokine Interleukin-6. Pssm-ID: 401252 Cd Length: 96 Bit Score: 53.57 E-value: 3.67e-09
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IL3Ra_N | pfam18611 | IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell ... |
149-209 | 2.78e-03 | ||
IL-3 receptor alpha chain N-terminal domain; Interleukin-3 (IL-3) is an activated T cell product that bridges innate and adaptive immunity and contributes to several immunopathologies. Structure of IL-3 receptor alpha chain (IL3Ra) in complex with the anti-leukemia antibody CSL362 reveals that the N-terminal domain (NTD), a domain also present in the granulocyte-macrophage colony-stimulating factor (GM-CSF), contains the CSL362 binding epitope. Furthermore, NTD of IL3Ra adopts a typical fibronectin type III (FnIII) fold. Pssm-ID: 436618 Cd Length: 76 Bit Score: 36.56 E-value: 2.78e-03
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Blast search parameters | ||||
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