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Conserved domains on  [gi|1907143988|ref|XP_036018617|]
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cilia- and flagella-associated protein 61 isoform X6 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NirB super family cl34210
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
419-524 1.75e-07

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


The actual alignment was detected with superfamily member COG1251:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 54.76  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  419 RIVVVGASSVGISFLETLVfcsHLKFN-NLTLIS------------THGLPGKRllhNEQRKFLASDHCFNDKDyalmsl 485
Cdd:COG1251      3 RIVIIGAGMAGVRAAEELR---KLDPDgEITVIGaephppynrpplSKVLAGET---DEEDLLLRPADFYEENG------ 70

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1907143988  486 cswVNVVVG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTG 524
Cdd:COG1251     71 ---IDLRLGtRVTAIDRAARTVTLADGETLPYDKLVLATG 107
CFAP61_N super family cl24607
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 1-27 2.12e-04

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


The actual alignment was detected with superfamily member pfam16092:

Pssm-ID: 465016  Cd Length: 264  Bit Score: 44.16  E-value: 2.12e-04
                           10        20
                   ....*....|....*....|....*..
gi 1907143988    1 MSVCTSVNLPLLHECFDLGPFHGFCTP 27
Cdd:pfam16092  238 MSLSSDVDIRLLNENFELEPFGNLVKP 264
CFAP61_N super family cl24607
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 162-296 4.70e-03

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


The actual alignment was detected with superfamily member pfam16092:

Pssm-ID: 465016  Cd Length: 264  Bit Score: 39.92  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  162 VFSLFPGKNFCLISVP-------HLTPEFVLIQ---------NFVKVVPFNNCTLdhdlYVFHRAGLLRSITIRLAKfld 225
Cdd:pfam16092  112 VFYAEPKLHFIILVKPpqyelepALAEIFEPLEkygkvyyprEFSHTKNVNTPSI----YICHRHDHMPKLHVRKAR--- 184

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907143988  226 tagVEK---LVSTLLLSTKILDD-LAQY--NEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDF 296
Cdd:pfam16092  185 ---VEDnddLVEIFERQSPELREtYGDYflAELIEAQDEENKAIIVAEVDGKAVGFMSLSSDVDIRLLNENFELEPF 258
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
419-524 1.75e-07

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 54.76  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  419 RIVVVGASSVGISFLETLVfcsHLKFN-NLTLIS------------THGLPGKRllhNEQRKFLASDHCFNDKDyalmsl 485
Cdd:COG1251      3 RIVIIGAGMAGVRAAEELR---KLDPDgEITVIGaephppynrpplSKVLAGET---DEEDLLLRPADFYEENG------ 70

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1907143988  486 cswVNVVVG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTG 524
Cdd:COG1251     71 ---IDLRLGtRVTAIDRAARTVTLADGETLPYDKLVLATG 107
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 420-538 1.85e-05

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 48.67  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  420 IVVVGASSVGISFLETLVFCSHLKFNnLTLISTHGLPgkrllhNEQRKFLASdHCFNDKDYALMSLCSW-------VNVV 492
Cdd:TIGR02374    1 LVLVGNGMAGHRCIEEVLKLNRHMFE-ITIFGEEPHP------NYNRILLSS-VLQGEADLDDITLNSKdwyekhgITLY 72

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1907143988  493 VG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTE 538
Cdd:TIGR02374   73 TGeTVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKK 119
CFAP61_N pfam16092
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 1-27 2.12e-04

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


Pssm-ID: 465016  Cd Length: 264  Bit Score: 44.16  E-value: 2.12e-04
                           10        20
                   ....*....|....*....|....*..
gi 1907143988    1 MSVCTSVNLPLLHECFDLGPFHGFCTP 27
Cdd:pfam16092  238 MSLSSDVDIRLLNENFELEPFGNLVKP 264
CFAP61_N pfam16092
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 162-296 4.70e-03

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


Pssm-ID: 465016  Cd Length: 264  Bit Score: 39.92  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  162 VFSLFPGKNFCLISVP-------HLTPEFVLIQ---------NFVKVVPFNNCTLdhdlYVFHRAGLLRSITIRLAKfld 225
Cdd:pfam16092  112 VFYAEPKLHFIILVKPpqyelepALAEIFEPLEkygkvyyprEFSHTKNVNTPSI----YICHRHDHMPKLHVRKAR--- 184

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907143988  226 tagVEK---LVSTLLLSTKILDD-LAQY--NEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDF 296
Cdd:pfam16092  185 ---VEDnddLVEIFERQSPELREtYGDYflAELIEAQDEENKAIIVAEVDGKAVGFMSLSSDVDIRLLNENFELEPF 258
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
419-524 1.75e-07

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 54.76  E-value: 1.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  419 RIVVVGASSVGISFLETLVfcsHLKFN-NLTLIS------------THGLPGKRllhNEQRKFLASDHCFNDKDyalmsl 485
Cdd:COG1251      3 RIVIIGAGMAGVRAAEELR---KLDPDgEITVIGaephppynrpplSKVLAGET---DEEDLLLRPADFYEENG------ 70

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 1907143988  486 cswVNVVVG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTG 524
Cdd:COG1251     71 ---IDLRLGtRVTAIDRAARTVTLADGETLPYDKLVLATG 107
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 489-544 2.04e-06

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 50.97  E-value: 2.04e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907143988  489 VNVVVG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNR 544
Cdd:COG0446     51 IDVRTGtEVTAIDPEAKTVTLRDGETLSYDKLVLATGARPRPPPIPGLDLPGVFTLR 107
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
418-524 6.08e-06

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 49.75  E-value: 6.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  418 ARIVVVGASSVGISFLETLvfCSHLKFN-NLTLISthglpgKRLLHNEQ-------RKFLASDHCfndkDYALMSLCSW- 488
Cdd:COG1252      2 KRIVIVGGGFAGLEAARRL--RKKLGGDaEVTLID------PNPYHLFQpllpevaAGTLSPDDI----AIPLRELLRRa 69

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 1907143988  489 -VNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTG 524
Cdd:COG1252     70 gVRFIQGEVTGIDPEARTVTLADGRTLSYDYLVIATG 106
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 420-538 1.85e-05

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 48.67  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  420 IVVVGASSVGISFLETLVFCSHLKFNnLTLISTHGLPgkrllhNEQRKFLASdHCFNDKDYALMSLCSW-------VNVV 492
Cdd:TIGR02374    1 LVLVGNGMAGHRCIEEVLKLNRHMFE-ITIFGEEPHP------NYNRILLSS-VLQGEADLDDITLNSKdwyekhgITLY 72

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1907143988  493 VG-RMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTE 538
Cdd:TIGR02374   73 TGeTVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPIPGADKK 119
CFAP61_N pfam16092
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 1-27 2.12e-04

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


Pssm-ID: 465016  Cd Length: 264  Bit Score: 44.16  E-value: 2.12e-04
                           10        20
                   ....*....|....*....|....*..
gi 1907143988    1 MSVCTSVNLPLLHECFDLGPFHGFCTP 27
Cdd:pfam16092  238 MSLSSDVDIRLLNENFELEPFGNLVKP 264
CFAP61_N pfam16092
Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the ...
 162-296 4.70e-03

Cilia- and flagella-associated protein 61, N-terminal domain; This entry represents the N-terminal domain of proteins described as cilia- and flagella-associated protein. Proteins containing this domain includes FAP61 from Chlamydomonas reinhardtii. FAP61 is part of the calmodulin and spoke-associated complex (CSC) required for wild-type motility and for the stable assembly of a subset of radial spokes in motile cilia.


Pssm-ID: 465016  Cd Length: 264  Bit Score: 39.92  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907143988  162 VFSLFPGKNFCLISVP-------HLTPEFVLIQ---------NFVKVVPFNNCTLdhdlYVFHRAGLLRSITIRLAKfld 225
Cdd:pfam16092  112 VFYAEPKLHFIILVKPpqyelepALAEIFEPLEkygkvyyprEFSHTKNVNTPSI----YICHRHDHMPKLHVRKAR--- 184

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907143988  226 tagVEK---LVSTLLLSTKILDD-LAQY--NEAGRDPDGTALQVFVAEVADQIVGIAVIRKEMDIEYIRSHYNIEDF 296
Cdd:pfam16092  185 ---VEDnddLVEIFERQSPELREtYGDYflAELIEAQDEENKAIIVAEVDGKAVGFMSLSSDVDIRLLNENFELEPF 258
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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