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Conserved domains on  [gi|1931720852|ref|XP_037490982|]
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apicoplast ribosomal protein L14 (apicoplast) [Plasmodium vinckei vinckei]

Protein Classification

uL14 family ribosomal protein( domain architecture ID 961)

uL14 family ribosomal protein similar to bacterial and chloroplast 50S ribosomal protein L14, human mitochondrial 39S ribosomal protein L14, and Paramecium mitochondrial tetraurelia 60S ribosomal protein L14

Gene Ontology:  GO:0003735|GO:0006412
PubMed:  24524803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_uL14 super family cl46262
Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in ...
 3-107 1.06e-14

Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in eukaryotes, L38 in fungal mitochondria) is part of the large ribosomal subunit, located between the centers of activity for peptidyl transferase and GTPase. uL14 has an "all beta" fold that binds 23S rRNA. Ribosomal proteins, which are components of ribosomal subunits, are RNA-binding proteins that might have multiple extra ribosomal functions and may be involved in tumorigenesis in mammals.


The actual alignment was detected with superfamily member cd00337:

Pssm-ID: 466774  Cd Length: 114  Bit Score: 64.78  E-value: 1.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931720852   3 YLNSILDVLDNSGILKFKYINTLNKS--KNIKYGDILMGIVYKLYNNNLYKKSDKCKGILVQYKHFINLKLYYSIKFNKN 80
Cdd:cd00337     1 QVGTRLNVADNSGAKKVKCIKVLGKKgrRYAGVGDIIVVSVKKAKPEKKVKKGEVVKAVIVRTKKEIRRKDGSYIRFDDN 80

                          90       100
                  ....*....|....*....|....*..
gi 1931720852  81 AVIILNNDLNSVGTKSNSIILKYIKYK 107
Cdd:cd00337    81 AVVLINKKGEPLGTRIFGPVARELRAK 107
 
Name Accession Description Interval E-value
Ribosomal_uL14 cd00337
Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in ...
 3-107 1.06e-14

Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in eukaryotes, L38 in fungal mitochondria) is part of the large ribosomal subunit, located between the centers of activity for peptidyl transferase and GTPase. uL14 has an "all beta" fold that binds 23S rRNA. Ribosomal proteins, which are components of ribosomal subunits, are RNA-binding proteins that might have multiple extra ribosomal functions and may be involved in tumorigenesis in mammals.


Pssm-ID: 466774  Cd Length: 114  Bit Score: 64.78  E-value: 1.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931720852   3 YLNSILDVLDNSGILKFKYINTLNKS--KNIKYGDILMGIVYKLYNNNLYKKSDKCKGILVQYKHFINLKLYYSIKFNKN 80
Cdd:cd00337     1 QVGTRLNVADNSGAKKVKCIKVLGKKgrRYAGVGDIIVVSVKKAKPEKKVKKGEVVKAVIVRTKKEIRRKDGSYIRFDDN 80

                          90       100
                  ....*....|....*....|....*..
gi 1931720852  81 AVIILNNDLNSVGTKSNSIILKYIKYK 107
Cdd:cd00337    81 AVVLINKKGEPLGTRIFGPVARELRAK 107
Ribosomal_L14 pfam00238
Ribosomal protein L14p/L23e;
3-94 4.11e-08

Ribosomal protein L14p/L23e;


Pssm-ID: 425547  Cd Length: 119  Bit Score: 47.77  E-value: 4.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931720852   3 YLNSILDVLDNSGILKFKYINTLNKSKnIKY---GDILMGIVYKLYNNNLYKKSDKCKGILVQYKHFINLKLYYSIKFNK 79
Cdd:pfam00238   1 QVGTRLNVADNSGAKEVMCIKVLGGSG-RRYasvGDIIVVSVKKAKPNGKVKKGDVVKAVVVRTKKEIRRPDGSYIRFDD 79

                          90
                  ....*....|....*
gi 1931720852  80 NAVIILNNDLNSVGT 94
Cdd:pfam00238  80 NAAVLINDKGEPKGT 94
 
Name Accession Description Interval E-value
Ribosomal_uL14 cd00337
Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in ...
 3-107 1.06e-14

Ribosomal protein uL14; Ribosomal protein uL14 (L14 in bacteria and mitochondria, L23 in eukaryotes, L38 in fungal mitochondria) is part of the large ribosomal subunit, located between the centers of activity for peptidyl transferase and GTPase. uL14 has an "all beta" fold that binds 23S rRNA. Ribosomal proteins, which are components of ribosomal subunits, are RNA-binding proteins that might have multiple extra ribosomal functions and may be involved in tumorigenesis in mammals.


Pssm-ID: 466774  Cd Length: 114  Bit Score: 64.78  E-value: 1.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931720852   3 YLNSILDVLDNSGILKFKYINTLNKS--KNIKYGDILMGIVYKLYNNNLYKKSDKCKGILVQYKHFINLKLYYSIKFNKN 80
Cdd:cd00337     1 QVGTRLNVADNSGAKKVKCIKVLGKKgrRYAGVGDIIVVSVKKAKPEKKVKKGEVVKAVIVRTKKEIRRKDGSYIRFDDN 80

                          90       100
                  ....*....|....*....|....*..
gi 1931720852  81 AVIILNNDLNSVGTKSNSIILKYIKYK 107
Cdd:cd00337    81 AVVLINKKGEPLGTRIFGPVARELRAK 107
Ribosomal_L14 pfam00238
Ribosomal protein L14p/L23e;
3-94 4.11e-08

Ribosomal protein L14p/L23e;


Pssm-ID: 425547  Cd Length: 119  Bit Score: 47.77  E-value: 4.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1931720852   3 YLNSILDVLDNSGILKFKYINTLNKSKnIKY---GDILMGIVYKLYNNNLYKKSDKCKGILVQYKHFINLKLYYSIKFNK 79
Cdd:pfam00238   1 QVGTRLNVADNSGAKEVMCIKVLGGSG-RRYasvGDIIVVSVKKAKPNGKVKKGDVVKAVVVRTKKEIRRPDGSYIRFDD 79

                          90
                  ....*....|....*
gi 1931720852  80 NAVIILNNDLNSVGT 94
Cdd:pfam00238  80 NAAVLINDKGEPKGT 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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