|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
936-1135 |
6.78e-52 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 185.16 E-value: 6.78e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 936 INSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLM 1015
Cdd:COG0666 46 ALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLH 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1016 MAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1095
Cdd:COG0666 126 LAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLL 205
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1958659049 1096 VDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1135
Cdd:COG0666 206 LEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADL 245
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
944-1135 |
1.05e-50 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 181.69 E-value: 1.05e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 944 GETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHL 1023
Cdd:COG0666 87 GNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNL 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1024 GTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIE 1103
Cdd:COG0666 167 EIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLN 246
|
170 180 190
....*....|....*....|....*....|..
gi 1958659049 1104 HVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1135
Cdd:COG0666 247 AKDKDGLTALLLAAAAGAALIVKLLLLALLLL 278
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
778-1113 |
1.73e-46 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 169.75 E-value: 1.73e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 778 LLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHL 857
Cdd:COG0666 4 LLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 858 DKNGQCALVHAALRGHLEVVKFLIQcdwtmAGqqqgvfkksqaiqqaliaaasmgyteivsylldlpekdeeeverAQIN 937
Cdd:COG0666 84 DDGGNTLLHAAARNGDLEIVKLLLE-----AG--------------------------------------------ADVN 114
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 938 SFDSlWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMA 1017
Cdd:COG0666 115 ARDK-DGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLA 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1018 ASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVD 1097
Cdd:COG0666 194 AENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLL 273
|
330
....*....|....*.
gi 1958659049 1098 HGAMIEHVDYSGMRPL 1113
Cdd:COG0666 274 ALLLLAAALLDLLTLL 289
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
761-1080 |
6.64e-44 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 162.05 E-value: 6.64e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 761 ALASLRNLYTPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGF 840
Cdd:COG0666 20 LLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 841 LSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQcdwtmAGqqqgvfkksqaiqqaliaaasmgyteivsyl 920
Cdd:COG0666 100 LEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLE-----AG------------------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 921 ldlpekdeeeverAQINSFDSlWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHG 1000
Cdd:COG0666 144 -------------ADVNAQDN-DGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAG 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1001 ADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPL 1080
Cdd:COG0666 210 ADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1014-1100 |
7.36e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.63 E-value: 7.36e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1014 LMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDhaDKNGRTPLDLAAFYGDAEVVQ 1093
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVNL--KDNGRTALHYAARSGHLEIVK 78
|
....*..
gi 1958659049 1094 FLVDHGA 1100
Cdd:pfam12796 79 LLLEKGA 85
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
919-1139 |
3.21e-19 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 93.17 E-value: 3.21e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 919 YLLDLPEKDEEEVER-----AQINsFDSLWGETALTAAAGRGK---LDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGH- 989
Cdd:PHA03095 18 YLLNASNVTVEEVRRllaagADVN-FRGEYGKTPLHLYLHYSSekvKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATt 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 990 WQIVDLLLTHGADVNMADKQGRTPLMMAAS--EGHLGTVDFLLAQGASIALMDKEGLTALswACL--------------- 1052
Cdd:PHA03095 97 LDVIKLLIKAGADVNAKDKVGRTPLHVYLSgfNINPKVIRLLLRKGADVNALDLYGMTPL--AVLlksrnanvellrlli 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1053 -KG----------------HL-------SVVRSLVDNGAATDHADKNGRTPLDLAAFYGD--AEVVQFLVDHGAMIEHVD 1106
Cdd:PHA03095 175 dAGadvyavddrfrsllhhHLqsfkpraRIVRELIRAGCDPAATDMLGNTPLHSMATGSSckRSLVLPLLIAGISINARN 254
|
250 260 270
....*....|....*....|....*....|...
gi 1958659049 1107 YSGMRPLDRAVGCRNTSVVVTLLKKGAKIGCQT 1139
Cdd:PHA03095 255 RYGQTPLHYAAVFNNPRACRRLIALGADINAVS 287
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
985-1067 |
1.92e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.70 E-value: 1.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 985 VRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGAsiALMDKEGLTALSWACLKGHLSVVRSLVD 1064
Cdd:pfam12796 5 AKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIVKLLLE 82
|
...
gi 1958659049 1065 NGA 1067
Cdd:pfam12796 83 KGA 85
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
766-1060 |
2.29e-18 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 90.47 E-value: 2.29e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 766 RNLYTPNIKVS--RLLILGGANINYRTEvLNNAPiLCVQSHLG---YTEMVALLLEFGANVDASSESGLTPLG-YAAAAG 839
Cdd:PHA03095 18 YLLNASNVTVEevRRLLAAGADVNFRGE-YGKTP-LHLYLHYSsekVKDIVRLLLEAGADVNAPERCGFTPLHlYLYNAT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 840 FLSIVVLLCKKRAKVDHLDKNGQCALvHAALRG---HLEVVKFLIQ-----CDWTMAGQQQ-GVFKKSQAIQQaliaaas 910
Cdd:PHA03095 96 TLDVIKLLIKAGADVNAKDKVGRTPL-HVYLSGfniNPKVIRLLLRkgadvNALDLYGMTPlAVLLKSRNANV------- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 911 mgytEIVSYLLDlpeKDEEEVERAqiNSFDSLWGETALTAaagRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHW 990
Cdd:PHA03095 168 ----ELLRLLID---AGADVYAVD--DRFRSLLHHHLQSF---KPRARIVRELIRAGCDPAATDMLGNTPLHSMATGSSC 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958659049 991 Q--IVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVR 1060
Cdd:PHA03095 236 KrsLVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVR 307
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
821-1116 |
7.12e-17 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 85.40 E-value: 7.12e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 821 VDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQcdwtmagqqQGVfkksqa 900
Cdd:PHA02874 28 INISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLID---------NGV------ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 901 iqqaliaaasmgyteiVSYLLDLPEKDEEEVER-----AQINSFDSLwGETALTAAAGRGKLDVCRLLLEQGAAVAQPNR 975
Cdd:PHA02874 93 ----------------DTSILPIPCIEKDMIKTildcgIDVNIKDAE-LKTFLHYAIKKGDLESIKMLFEYGADVNIEDD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 976 RGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGH 1055
Cdd:PHA02874 156 NGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNR 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958659049 1056 lSVVRSLVDNGAATDhADKNGRTPLDLAAFYG-DAEVVQFLVDHGAMIEHVDYSGMRPLDRA 1116
Cdd:PHA02874 236 -SAIELLINNASIND-QDIDGSTPLHHAINPPcDIDIIDILLYHKADISIKDNKGENPIDTA 295
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
945-1166 |
7.57e-17 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 85.04 E-value: 7.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 945 ETALTAAAGRGKLDVCRLLLEQGAavaQPN---RRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEG 1021
Cdd:PHA02875 3 QVALCDAILFGELDIARRLLDIGI---NPNfeiYDGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1022 HLGTVDFLLAQGASIA-LMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGA 1100
Cdd:PHA02875 80 DVKAVEELLDLGKFADdVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958659049 1101 MIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKI------GCQTLpsrprgpATWAMATSKPDIMIILLSK 1166
Cdd:PHA02875 160 CLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIdyfgknGCVAA-------LCYAIENNKIDIVRLFIKR 224
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
948-1040 |
1.03e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 77.08 E-value: 1.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 948 LTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHgADVNMADkQGRTPLMMAASEGHLGTVD 1027
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 1958659049 1028 FLLAQGASIALMD 1040
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
956-1135 |
1.62e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 84.33 E-value: 1.62e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 956 KLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQ-----IVDLLLTHGADVNMADKQGRTPLMMAASE--GHLGTVDF 1028
Cdd:PHA03100 47 NIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNLtdvkeIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEY 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1029 LLAQGASIALMDKEGLTALSWA--CLKGHLSVVRSLVDNGA----------------ATDHADKNGRTPLDLAAFYGDAE 1090
Cdd:PHA03100 127 LLDNGANVNIKNSDGENLLHLYleSNKIDLKILKLLIDKGVdinaknrvnyllsygvPINIKDVYGFTPLHYAVYNNNPE 206
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1958659049 1091 VVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1135
Cdd:PHA03100 207 FVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSI 251
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
1047-1138 |
3.22e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 75.54 E-value: 3.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1047 LSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHgAMIEHVDYsGMRPLDRAVGCRNTSVVV 1126
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVK 78
|
90
....*....|..
gi 1958659049 1127 TLLKKGAKIGCQ 1138
Cdd:pfam12796 79 LLLEKGADINVK 90
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
809-1075 |
7.52e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 82.02 E-value: 7.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 809 EMVALLLEFGANVDASSESGLTPLGYAAAAGF-----LSIVVLLCKKRAKVDHLDKNGQCALVHAALRghlevvkfliqc 883
Cdd:PHA03100 49 DVVKILLDNGADINSSTKNNSTPLHYLSNIKYnltdvKEIVKLLLEYGANVNAPDNNGITPLLYAISK------------ 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 884 dwtmagqqqgvfkksqaiqqaliaaaSMGYTEIVSYLLDLpekdeeeveRAQINSFDSlWGETALTAAA--GRGKLDVCR 961
Cdd:PHA03100 117 --------------------------KSNSYSIVEYLLDN---------GANVNIKNS-DGENLLHLYLesNKIDLKILK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 962 LLLEQGAAVAQPNRrgavplfstvrqghwqiVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDK 1041
Cdd:PHA03100 161 LLIDKGVDINAKNR-----------------VNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNK 223
|
250 260 270
....*....|....*....|....*....|....
gi 1958659049 1042 EGLTALSWACLKGHLSVVRSLVDNGAATDHADKN 1075
Cdd:PHA03100 224 YGDTPLHIAILNNNKEIFKLLLNNGPSIKTIIET 257
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
773-1135 |
7.94e-16 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 83.57 E-value: 7.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 773 IKVSRLLILGGANINYRtEVLNNAPILCVQSHlGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRA 852
Cdd:PHA02876 158 LLIAEMLLEGGADVNAK-DIYCITPIHYAAER-GNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIIDNRS 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 853 KVDHLDkngqCALVHAALRGHLEVVKFLIQCDWTMagQQQGVFKKSQAIQQALIAAASmgytEIVSYLLdlpekdeeevE 932
Cdd:PHA02876 236 NINKND----LSLLKAIRNEDLETSLLLYDAGFSV--NSIDDCKNTPLHHASQAPSLS----RLVPKLL----------E 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 933 RAQINSFDSLWGETALTAAAGRG-KLDVCRLLLEQGAAVAQPNRRGAVPLF-STVRQGHWQIVDLLLTHGADVNMADKQG 1010
Cdd:PHA02876 296 RGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYITPLHqASTLDRNKDIVITLLELGANVNARDYCD 375
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1011 RTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWA-CLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYG-D 1088
Cdd:PHA02876 376 KTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYACKKNcK 455
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1958659049 1089 AEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRntSVVVTLLKKGAKI 1135
Cdd:PHA02876 456 LDVIEMLLDNGADVNAINIQNQYPLLIALEYH--GIVNILLHYGAEL 500
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
946-1129 |
2.25e-15 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 80.78 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 946 TALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGAD----------------------- 1002
Cdd:PHA02874 37 TPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGVDtsilpipciekdmiktildcgid 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1003 VNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDL 1082
Cdd:PHA02874 117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHN 196
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 1958659049 1083 AAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVgCRNTSVVVTLL 1129
Cdd:PHA02874 197 AAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAI-IHNRSAIELLI 242
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
806-884 |
3.07e-14 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 69.76 E-value: 3.07e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958659049 806 GYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKrAKVDHLDkNGQCALVHAALRGHLEVVKFLIQCD 884
Cdd:pfam12796 8 GNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVKLLLEKG 84
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
991-1135 |
1.55e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 75.30 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 991 QIVDLLLTHGADVNMADK-QGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAAT 1069
Cdd:PHA02878 148 EITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958659049 1070 DHADKNGRTPLDLAAFY-GDAEVVQFLVDHGAMIEHVDY-SGMRPLDRAVgcRNTSVVVTLLKKGAKI 1135
Cdd:PHA02878 228 DARDKCGNTPLHISVGYcKDYDILKLLLEHGVDVNAKSYiLGLTALHSSI--KSERKLKLLLEYGADI 293
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
912-1133 |
2.64e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 71.18 E-value: 2.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 912 GYTEIVSYLLDLpekdeeeveraQIN-SFDSLWGETALTAAAGRGKLDVCRLLLEQGAA--VAQPNRRGavPLFSTVRQG 988
Cdd:PHA02875 13 GELDIARRLLDI-----------GINpNFEIYDGISPIKLAMKFRDSEAIKLLMKHGAIpdVKYPDIES--ELHDAVEEG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 989 HWQIVDLLLTHGADVN-MADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGA 1067
Cdd:PHA02875 80 DVKAVEELLDLGKFADdVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKA 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1068 ATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAmieHVDYSGMRP----LDRAVGCRNTSVVVTLLKKGA 1133
Cdd:PHA02875 160 CLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGA---NIDYFGKNGcvaaLCYAIENNKIDIVRLFIKRGA 226
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
832-968 |
6.16e-12 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 63.21 E-value: 6.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 832 LGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIqcdwtmagqqqgvfkksqaiqqaliaaasm 911
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLL------------------------------ 50
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659049 912 gyteivsylldlpekdeeevERAQINSFDSlwGETALTAAAGRGKLDVCRLLLEQGA 968
Cdd:pfam12796 51 --------------------EHADVNLKDN--GRTALHYAARSGHLEIVKLLLEKGA 85
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
957-1140 |
7.66e-12 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 70.67 E-value: 7.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 957 LDVCRLLLEQGAAVAQPNRrgAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASI 1036
Cdd:PLN03192 507 LNVGDLLGDNGGEHDDPNM--ASNLLTVASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNV 584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1037 ALMDKEGLTALSWACLKGHLSVVRSLVDNGAATD-HAdknGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDR 1115
Cdd:PLN03192 585 HIRDANGNTALWNAISAKHHKIFRILYHFASISDpHA---AGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQV 661
|
170 180
....*....|....*....|....*
gi 1958659049 1116 AVGCRNTSVVVTLLKKGAKIGCQTL 1140
Cdd:PLN03192 662 AMAEDHVDMVRLLIMNGADVDKANT 686
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
1043-1096 |
1.89e-11 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 60.75 E-value: 1.89e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1043 GLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLV 1096
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
1171-1286 |
1.91e-11 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 66.18 E-value: 1.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG0457 15 GLAYRRLGRYEEAIEDYEKALELDPDD-------------AEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNN 81
|
90 100 110
....*....|....*....|....*....|....*.
gi 1958659049 1251 RARAkRSSSRQFAAALEDLKEAIKLCPNNREIQRLL 1286
Cdd:COG0457 82 LGLA-LQALGRYEEALEDYDKALELDPDDAEALYNL 116
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
1171-1286 |
1.08e-10 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 63.87 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG0457 49 GLAYLRLGRYEEALADYEQALELDPDD-------------AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYN 115
|
90 100 110
....*....|....*....|....*....|....*.
gi 1958659049 1251 RARAKRSSSRqFAAALEDLKEAIKLCPNNREIQRLL 1286
Cdd:COG0457 116 LGLALLELGR-YDEAIEAYERALELDPDDADALYNL 150
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
985-1140 |
1.25e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 66.63 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 985 VRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVD 1064
Cdd:PHA02876 153 IQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKAIID 232
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659049 1065 NGAatdHADKNGRTPLDlAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTS-VVVTLLKKGAKIGCQTL 1140
Cdd:PHA02876 233 NRS---NINKNDLSLLK-AIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHASQAPSLSrLVPKLLERGADVNAKNI 305
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
1171-1279 |
2.49e-10 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 60.21 E-value: 2.49e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG4783 45 GEILLQLGDLDEAIVLLHEALELDPDE-------------PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLR 111
|
90 100
....*....|....*....|....*....
gi 1958659049 1251 RARAKRsSSRQFAAALEDLKEAIKLCPNN 1279
Cdd:COG4783 112 LARAYR-ALGRPDEAIAALEKALELDPDD 139
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
774-1106 |
4.86e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 63.83 E-value: 4.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 774 KVSRLLILGGANinyrTEVLnnaPILCVQShlgytEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAK 853
Cdd:PHA02874 82 DIIKLLIDNGVD----TSIL---PIPCIEK-----DMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGAD 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 854 VDHLDKNGqCALVHAALRGhlevvkfliqcdwtmagqqqgvfkksqaiqqaliaaasmgyteivsylldlpekdeeever 933
Cdd:PHA02874 150 VNIEDDNG-CYPIHIAIKH------------------------------------------------------------- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 934 aqiNSFdslwgetaltaaagrgklDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTP 1013
Cdd:PHA02874 168 ---NFF------------------DIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTP 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1014 LMMAASegHLGTVDFLLAQGASIALMDKEGLTALSWA----CLKghlSVVRSLVDNGAATDHADKNGRTPLDLAAFY-GD 1088
Cdd:PHA02874 227 LHNAII--HNRSAIELLINNASINDQDIDGSTPLHHAinppCDI---DIIDILLYHKADISIKDNKGENPIDTAFKYiNK 301
|
330
....*....|....*...
gi 1958659049 1089 AEVVQFLVDHGAMIEHVD 1106
Cdd:PHA02874 302 DPVIKDIIANAVLIKEAD 319
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
1174-1281 |
5.60e-10 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 57.87 E-value: 5.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1174 FYKKGKVKEAAQRYQYALKKFPREGfgedlktfrelkvSLLLNLSRCRRKMNDFGMAEEFaTKALELKPKSYEAYYARAR 1253
Cdd:COG3063 2 YLKLGDLEEAEEYYEKALELDPDNA-------------DALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAE 67
|
90 100
....*....|....*....|....*...
gi 1958659049 1254 AKRsSSRQFAAALEDLKEAIKLCPNNRE 1281
Cdd:COG3063 68 LLL-ELGDYDEALAYLERALELDPSALR 94
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
1164-1289 |
5.72e-10 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 59.44 E-value: 5.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1164 LSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPK 1243
Cdd:COG4783 4 AEALYALAQALLLAGDYDEAEALLEKALELDPDN-------------PEAFALLGEILLQLGDLDEAIVLLHEALELDPD 70
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1958659049 1244 SYEAYYARARAKRsSSRQFAAALEDLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG4783 71 EPEARLNLGLALL-KAGDYDEALALLEKALKLDPEHPEAYLRLARA 115
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
1171-1288 |
7.01e-10 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 64.24 E-value: 7.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG3914 119 GNLLLALGRLEEALAALRRALALNPDF-------------AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNN 185
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958659049 1251 RARAKRSSSRqFAAALEDLKEAIKLCPNNREIQRLLMR 1288
Cdd:COG3914 186 LGNALQDLGR-LEEAIAAYRRALELDPDNADAHSNLLF 222
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
1174-1289 |
8.75e-10 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 63.86 E-value: 8.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1174 FYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARAR 1253
Cdd:COG3914 88 LQALGRYEEALALYRRALALNPDN-------------AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGE 154
|
90 100 110
....*....|....*....|....*....|....*.
gi 1958659049 1254 AkRSSSRQFAAALEDLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG3914 155 A-LRRLGRLEEAIAALRRALELDPDNAEALNNLGNA 189
|
|
| PHA02798 |
PHA02798 |
ankyrin-like protein; Provisional |
956-1108 |
1.01e-09 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222931 [Multi-domain] Cd Length: 489 Bit Score: 63.32 E-value: 1.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 956 KLDVCRLLLEQGAAVAQPNRRGAVPLFSTVR-----QGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLL 1030
Cdd:PHA02798 50 STDIVKLFINLGANVNGLDNEYSTPLCTILSnikdyKHMLDIVKILIENGADINKKNSDGETPLYCLLSNGYINNLEILL 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1031 ---AQGASIALMDKEGLTALSWACLKGH---LSVVRSLVDNGAATD-HADKNGRTPLDLAAFYG----DAEVVQFLVDHG 1099
Cdd:PHA02798 130 fmiENGADTTLLDKDGFTMLQVYLQSNHhidIEIIKLLLEKGVDINtHNNKEKYDTLHCYFKYNidriDADILKLFVDNG 209
|
....*....
gi 1958659049 1100 AMIEHVDYS 1108
Cdd:PHA02798 210 FIINKENKS 218
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1167-1289 |
1.10e-09 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 61.28 E-value: 1.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1167 LMEEGDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYE 1246
Cdd:COG2956 79 LLELAQDYLKAGLLDRAEELLEKLLELDPDD-------------AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH 145
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1958659049 1247 AYYARARAKRSSSrQFAAALEDLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG2956 146 AYCELAELYLEQG-DYDEAIEALEKALKLDPDCARALLLLAEL 187
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
1016-1098 |
3.86e-09 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 61.84 E-value: 3.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1016 MAASEGHLGtVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFL 1095
Cdd:PTZ00322 89 LAASGDAVG-ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLL 167
|
...
gi 1958659049 1096 VDH 1098
Cdd:PTZ00322 168 SRH 170
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
956-1135 |
5.22e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 61.23 E-value: 5.22e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 956 KLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVD-------- 1027
Cdd:PHA02876 157 ELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSVLECAVDSKNIDTIKaiidnrsn 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1028 ---------------------FLLAQGASIALMDKEGLTALSWACLKGHLS-VVRSLVDNGAATDHADKNGRTPLDLAAF 1085
Cdd:PHA02876 237 inkndlsllkairnedletslLLYDAGFSVNSIDDCKNTPLHHASQAPSLSrLVPKLLERGADVNAKNIKGETPLYLMAK 316
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1958659049 1086 YG-DAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGC-RNTSVVVTLLKKGAKI 1135
Cdd:PHA02876 317 NGyDTENIRTLIMLGADVNAADRLYITPLHQASTLdRNKDIVITLLELGANV 368
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
1182-1286 |
5.62e-09 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 56.17 E-value: 5.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1182 EAAQRYQYALKKFPREGFGedlktfrelkvslLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRSSSrQ 1261
Cdd:COG4235 1 EAIARLRQALAANPNDAEG-------------WLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-D 66
|
90 100
....*....|....*....|....*
gi 1958659049 1262 FAAALEDLKEAIKLCPNNREIQRLL 1286
Cdd:COG4235 67 TEEAEELLERALALDPDNPEALYLL 91
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
770-1009 |
7.06e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 60.06 E-value: 7.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 770 TPNIKVSRLLILGGANINYRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGF--LSIVVLL 847
Cdd:PHA03100 83 TDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKKSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKidLKILKLL 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 848 CKKRAKVDHLDKngqcalvhaalrghlevVKFLIqcdwtmagqqqgvfkksqaiqqaliaaasmgyteivSYLLDLPEKD 927
Cdd:PHA03100 163 IDKGVDINAKNR-----------------VNYLL------------------------------------SYGVPINIKD 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 928 EeeveraqinsfdslWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD 1007
Cdd:PHA03100 190 V--------------YGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKTII 255
|
..
gi 1958659049 1008 KQ 1009
Cdd:PHA03100 256 ET 257
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
980-1133 |
8.09e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 59.98 E-value: 8.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 980 PLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALmdkegltaLSWACLKGHLsvV 1059
Cdd:PHA02874 38 PLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGVDTSI--------LPIPCIEKDM--I 107
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1060 RSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKGA 1133
Cdd:PHA02874 108 KTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGA 181
|
|
| NrfG |
COG4235 |
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ... |
1171-1285 |
9.11e-09 |
|
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443378 [Multi-domain] Cd Length: 131 Bit Score: 55.78 E-value: 9.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG4235 24 GRAYLRLGRYDEALAAYEKALRLDPDN-------------ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYL 90
|
90 100 110
....*....|....*....|....*....|....*
gi 1958659049 1251 RARAkRSSSRQFAAALEDLKEAIKLCPNNREIQRL 1285
Cdd:COG4235 91 LGLA-AFQQGDYAEAIAAWQKLLALLPADAPARLL 124
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
934-1098 |
9.34e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 59.89 E-value: 9.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 934 AQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTP 1013
Cdd:PHA02878 158 ADINMKDRHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTP 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1014 LMMAASE-GHLGTVDFLLAQGASI-ALMDKEGLTALswaclkgHLS-----VVRSLVDNGAATDHADKNGRTPLDLAAF- 1085
Cdd:PHA02878 238 LHISVGYcKDYDILKLLLEHGVDVnAKSYILGLTAL-------HSSikserKLKLLLEYGADINSLNSYKLTPLSSAVKq 310
|
170
....*....|...
gi 1958659049 1086 YGDAEVVQFLVDH 1098
Cdd:PHA02878 311 YLCINIGRILISN 323
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
1010-1063 |
1.09e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 53.05 E-value: 1.09e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1010 GRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLV 1063
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
993-1113 |
1.11e-08 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 60.30 E-value: 1.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 993 VDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTALSWACLKGHLSVVRSLVdnGAATDHA 1072
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLS--RHSQCHF 175
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1958659049 1073 DKNGRTPLDlaAFYGdaeVVQFLVDHGAMIEHVDYSGM-RPL 1113
Cdd:PTZ00322 176 ELGANAKPD--SFTG---KPPSLEDSPISSHHPDFSAVpQPM 212
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
1182-1289 |
1.68e-08 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 55.74 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1182 EAAQRYQYALKKFPREGFGEDLKTFRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAKRsSSRQ 1261
Cdd:COG5010 25 EKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYS-RSGD 103
|
90 100
....*....|....*....|....*...
gi 1958659049 1262 FAAALEDLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG5010 104 KDEAKEYYEKALALSPDNPNAYSNLAAL 131
|
|
| TadD |
COG5010 |
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ... |
1173-1277 |
2.44e-08 |
|
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444034 [Multi-domain] Cd Length: 155 Bit Score: 54.97 E-value: 2.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1173 MFYKKGKVKEAAQRYQYALKKFPREGfgedlktfrelkvSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARA 1252
Cdd:COG5010 63 LYNKLGDFEESLALLEQALQLDPNNP-------------ELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLA 129
|
90 100
....*....|....*....|....*
gi 1958659049 1253 RAKRSSSRqFAAALEDLKEAIKLCP 1277
Cdd:COG5010 130 ALLLSLGQ-DDEAKAALQRALGTSP 153
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
1076-1129 |
3.26e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.51 E-value: 3.26e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1076 GRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLL 1129
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
1214-1279 |
3.27e-08 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 56.55 E-value: 3.27e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 1214 LLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAkRSSSRQFAAALEDLKEAIKLCPNN 1279
Cdd:COG0457 11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLA-YLRLGRYEEALADYEQALELDPDD 75
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
1171-1256 |
5.41e-08 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 52.69 E-value: 5.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREGFGEDLktfrelkvslLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG1729 37 GEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDA----------LLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKEA 106
|
....*.
gi 1958659049 1251 RARAKR 1256
Cdd:COG1729 107 RARLAR 112
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
1167-1281 |
1.07e-07 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 54.54 E-value: 1.07e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1167 LMEEGDMFYKKGKVKEAAQRYQYALKKFPRegfgedlktfrelKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYE 1246
Cdd:COG4785 76 YYERGVAYDSLGDYDLAIADFDQALELDPD-------------LAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAY 142
|
90 100 110
....*....|....*....|....*....|....*
gi 1958659049 1247 AYYARARAKRSSSRqFAAALEDLKEAIKLCPNNRE 1281
Cdd:COG4785 143 AYLNRGIALYYLGR-YELAIADLEKALELDPNDPE 176
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
980-1030 |
1.09e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.97 E-value: 1.09e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1958659049 980 PLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLL 1030
Cdd:pfam13637 4 ALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
828-881 |
1.78e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.58 E-value: 1.78e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 828 GLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLI 881
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
777-858 |
2.04e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 50.50 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 777 RLLILGGANINYRTEVLNNAPILCVQShlGYTEMVALLLEFgANVDASSEsGLTPLGYAAAAGFLSIVVLLCKKRAKVDH 856
Cdd:pfam12796 14 KLLLENGADANLQDKNGRTALHLAAKN--GHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEKGADINV 89
|
..
gi 1958659049 857 LD 858
Cdd:pfam12796 90 KD 91
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
797-847 |
2.10e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.20 E-value: 2.10e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1958659049 797 PILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLL 847
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
|
|
| NlpI |
COG4785 |
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis]; |
1140-1279 |
2.80e-07 |
|
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443815 [Multi-domain] Cd Length: 223 Bit Score: 53.38 E-value: 2.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1140 LPSRPRGPATWAMATSKPDIMiillSKLMEEGDMFYKkgkVKEAAQRYQYALKKFPREGFGEDLKTFRELK----VSLLL 1215
Cdd:COG4785 5 ALALLLALALAAAAASKAAIL----LAALLFAAVLAL---AIALADLALALAAAALAAAALAAERIDRALAlpdlAQLYY 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1216 NLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAkRSSSRQFAAALEDLKEAIKLCPNN 1279
Cdd:COG4785 78 ERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLA-YLLLGDYDAALEDFDRALELDPDY 140
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
772-1007 |
3.09e-07 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 55.64 E-value: 3.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 772 NIKVSRLLilgGANINYRTEVLNNAPILCVQShLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKR 851
Cdd:PLN03192 506 DLNVGDLL---GDNGGEHDDPNMASNLLTVAS-TGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHA 581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 852 AKVDHLDKNGQCALVHAALRGHLEVVKFLIQCdwtmagqqqgvfkksqaiqqaliaaasmgyteivsylldlpekdeeev 931
Cdd:PLN03192 582 CNVHIRDANGNTALWNAISAKHHKIFRILYHF------------------------------------------------ 613
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 932 erAQINsfDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMAD 1007
Cdd:PLN03192 614 --ASIS--DPHAAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKAN 685
|
|
| TPR |
COG0457 |
Tetratricopeptide (TPR) repeat [General function prediction only]; |
1171-1288 |
6.85e-07 |
|
Tetratricopeptide (TPR) repeat [General function prediction only];
Pssm-ID: 440225 [Multi-domain] Cd Length: 245 Bit Score: 52.70 E-value: 6.85e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYA 1250
Cdd:COG0457 83 GLALQALGRYEEALEDYDKALELDPDD-------------AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYN 149
|
90 100 110
....*....|....*....|....*....|....*...
gi 1958659049 1251 RARAKRSSSRqFAAALEDLKEAIKLCPNNREIQRLLMR 1288
Cdd:COG0457 150 LGIALEKLGR-YEEALELLEKLEAAALAALLAAALGEA 186
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
996-1047 |
8.98e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 47.73 E-value: 8.98e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 1958659049 996 LLTHG-ADVNMADKQGRTPLMMAASEGHLGTVDFLLAQGASIALMDKEGLTAL 1047
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
1210-1286 |
1.02e-06 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 49.81 E-value: 1.02e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958659049 1210 KVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYEAYYARARAkRSSSRQFAAALEDLKEAIKLCPNNREIQRLL 1286
Cdd:COG4783 3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEI-LLQLGDLDEAIVLLHEALELDPDEPEARLNL 78
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1159-1289 |
1.31e-06 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 52.04 E-value: 1.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1159 IMIILLSKLMEEGDMFYKKGKVKEAAQRYQYALKKFPREgfgedlktfrelkVSLLLNLSRCRRKMNDFGMAEEFATKAL 1238
Cdd:COG2956 3 LPVAAALGWYFKGLNYLLNGQPDKAIDLLEEALELDPET-------------VEAHLALGNLYRRRGEYDRAIRIHQKLL 69
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1958659049 1239 ELKPKSYEAYYARARAKRsSSRQFAAALEDLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG2956 70 ERDPDRAEALLELAQDYL-KAGLLDRAEELLEKLLELDPDDAEALRLLAEI 119
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
1040-1083 |
1.36e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.96 E-value: 1.36e-06
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 1958659049 1040 DKEGLTALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLA 1083
Cdd:pfam13857 13 DGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
830-1096 |
3.63e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 51.94 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 830 TPLGYAAAAGFL-SIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVKFLIQCDWTMAGQqqgvfkksqaiqqaliaa 908
Cdd:cd22192 19 SPLLLAAKENDVqAIKKLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPELVNE------------------ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 909 asmgytEIVSyllDLPEkdeeeveraqinsfdslwGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAV--------- 979
Cdd:cd22192 81 ------PMTS---DLYQ------------------GETALHIAVVNQNLNLVRELIARGADVVSPRATGTFfrpgpknli 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 980 -----PLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTV----DFLLAqgasialMDKEgltalswa 1050
Cdd:cd22192 134 yygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHILVLQPNKTFAcqmyDLILS-------YDKE-------- 198
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1958659049 1051 clkghlsvvrslvDNGAATDH-ADKNGRTPLDLAAFYGDAEVVQFLV 1096
Cdd:cd22192 199 -------------DDLQPLDLvPNNQGLTPFKLAAKEGNIVMFQHLV 232
|
|
| PilF |
COG3063 |
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures]; |
1220-1289 |
4.46e-06 |
|
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
Pssm-ID: 442297 [Multi-domain] Cd Length: 94 Bit Score: 46.70 E-value: 4.46e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1220 CRRKMNDFGMAEEFATKALELKPKSYEAYYARARAkRSSSRQFAAALEdLKEAIKLCPNNREIQRLLMRV 1289
Cdd:COG3063 1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLL-LLEQGRYDEAIA-LEKALKLDPNNAEALLNLAEL 68
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1167-1285 |
9.37e-06 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 49.34 E-value: 9.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1167 LMEEGDMFYKKGKVKEAAQRYQYALKKFPRegfgedlktfrelKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYE 1246
Cdd:COG2956 147 YCELAELYLEQGDYDEAIEALEKALKLDPD-------------CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLP 213
|
90 100 110
....*....|....*....|....*....|....*....
gi 1958659049 1247 AYYARARAKRSSSrQFAAALEDLKEAIKLCPNNREIQRL 1285
Cdd:COG2956 214 ALPRLAELYEKLG-DPEEALELLRKALELDPSDDLLLAL 251
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
770-1003 |
1.72e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 49.68 E-value: 1.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 770 TPNIkvsRLLILGGANINyRTEVLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCK 849
Cdd:PHA02876 321 TENI---RTLIMLGADVN-AADRLYITPLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLD 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 850 KRAKVDHLDKNGQCALvHAALRGhlevvkfliqcdwtmagqqqgvfkksqaiqqaliaaaSMGYTEiVSYLLDlpekdee 929
Cdd:PHA02876 397 YGADIEALSQKIGTAL-HFALCG-------------------------------------TNPYMS-VKTLID------- 430
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 930 evERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQGAAVAQPNRRGAVPLFstVRQGHWQIVDLLLTHGADV 1003
Cdd:PHA02876 431 --RGANVNSKNKDLSTPLHYACKKNCKLDVIEMLLDNGADVNAINIQNQYPLL--IALEYHGIVNILLHYGAEL 500
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
963-1113 |
4.24e-05 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 48.13 E-value: 4.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 963 LLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPL--MMAASEGHLGTVDFLLAQGASI-ALM 1039
Cdd:PHA02946 58 LLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLyyLSGTDDEVIERINLLVQYGAKInNSV 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 1040 DKEGLTALsWACLKGHLSVVRSLVDNGAATDHADKNGRTPL--DLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPL 1113
Cdd:PHA02946 138 DEEGCGPL-LACTDPSERVFKKIMSIGFEARIVDKFGKNHIhrHLMSDNPKASTISWMMKLGISPSKPDHDGNTPL 212
|
|
| CpoB |
COG1729 |
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ... |
1174-1284 |
4.97e-05 |
|
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 441335 [Multi-domain] Cd Length: 113 Bit Score: 44.21 E-value: 4.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1174 FYKKGKVKEAAQRYQYALKKFPREgfgedlktfrELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSY---EAYYA 1250
Cdd:COG1729 3 LLKAGDYDEAIAAFKAFLKRYPNS----------PLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPkapDALLK 72
|
90 100 110
....*....|....*....|....*....|....
gi 1958659049 1251 RARAkRSSSRQFAAALEDLKEAIKLCPNNREIQR 1284
Cdd:COG1729 73 LGLS-YLELGDYDKARATLEELIKKYPDSEAAKE 105
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
979-1135 |
5.46e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 47.95 E-value: 5.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 979 VPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLLA--------------------QGASIAL 1038
Cdd:PHA02878 39 IPLHQAVEARNLDVVKSLLTRGHNVNQPDHRDLTPLHIICKEPNKLGMKEMIRsinkcsvfytlvaikdafnnRNVEIFK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1039 M------DKEGLTALSWACLKGH-----LSVVRSLVDNGAATDHADKN-GRTPLDLAAFYGDAEVVQFLVDHGAMIEHVD 1106
Cdd:PHA02878 119 IiltnryKNIQTIDLVYIDKKSKddiieAEITKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPD 198
|
170 180
....*....|....*....|....*....
gi 1958659049 1107 YSGMRPLDRAVGCRNTSVVVTLLKKGAKI 1135
Cdd:PHA02878 199 KTNNSPLHHAVKHYNKPIVHILLENGAST 227
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
961-1030 |
6.71e-05 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 47.97 E-value: 6.71e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958659049 961 RLLLEQGAavaQPNRR---GAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVDFLL 1030
Cdd:PTZ00322 99 RILLTGGA---DPNCRdydGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLS 168
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
1075-1103 |
1.35e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 40.65 E-value: 1.35e-04
10 20
....*....|....*....|....*....
gi 1958659049 1075 NGRTPLDLAAFYGDAEVVQFLVDHGAMIE 1103
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADIN 29
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1075-1106 |
2.15e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.35 E-value: 2.15e-04
10 20 30
....*....|....*....|....*....|...
gi 1958659049 1075 NGRTPLDLAA-FYGDAEVVQFLVDHGAMIEHVD 1106
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1009-1041 |
2.28e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 39.97 E-value: 2.28e-04
10 20 30
....*....|....*....|....*....|....
gi 1958659049 1009 QGRTPLMMAA-SEGHLGTVDFLLAQGASIALMDK 1041
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARDK 34
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
926-1103 |
5.11e-04 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 45.07 E-value: 5.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 926 KDEEEVERAQINSFDSLWGETALTAAAGRGKLDVCRLLLEQgaavaqpNRRGAV--PLFSTVRQGHWQIVDLLLTHGADV 1003
Cdd:TIGR00870 35 RDLEEPKKLNINCPDRLGRSALFVAAIENENLELTELLLNL-------SCRGAVgdTLLHAISLEYVDAVEAILLHLLAA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1004 nmADKQGRTPLMMAASeghlgTVDFllaqgasialmdKEGLTALSWACLKGHLSVVRSLVDNGAA------------TDH 1071
Cdd:TIGR00870 108 --FRKSGPLELANDQY-----TSEF------------TPGITALHLAAHRQNYEIVKLLLERGASvparacgdffvkSQG 168
|
170 180 190
....*....|....*....|....*....|....
gi 1958659049 1072 AD--KNGRTPLDLAAFYGDAEVVQFLVDHGAMIE 1103
Cdd:TIGR00870 169 VDsfYHGESPLNAAACLGSPSIVALLSEDPADIL 202
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
963-1017 |
5.48e-04 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 39.64 E-value: 5.48e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 963 LLEQG-AAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGADVNMADKQGRTPLMMA 1017
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1167-1274 |
5.62e-04 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 43.95 E-value: 5.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1167 LMEEGDMFYKKGKVKEAAQRYQYALKKFPRegfgedlktfrelKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPKSYE 1246
Cdd:COG2956 181 LLLLAELYLEQGDYEEAIAALERALEQDPD-------------YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
|
90 100
....*....|....*....|....*....
gi 1958659049 1247 A-YYARARAKRsssRQFAAALEDLKEAIK 1274
Cdd:COG2956 248 LlALADLLERK---EGLEAALALLERQLR 273
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
777-861 |
6.43e-04 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 44.50 E-value: 6.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 777 RLLILGGANINYRTevLNNAPILCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDH 856
Cdd:PTZ00322 99 RILLTGGADPNCRD--YDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFE 176
|
....*
gi 1958659049 857 LDKNG 861
Cdd:PTZ00322 177 LGANA 181
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1349-1544 |
6.47e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.93 E-value: 6.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1349 GLQTEARPSQGLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDFRSNSSVGSPTRQGYQSTSPALSPThqnshyrPSPPHT 1428
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG-------PPPPSL 2850
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1429 SPAHQ---GASYRFSPPPVGGQGKEYPSPPPSPLR-------RGPQYRASPPAESMSIYRSQSGSPVRYQQEANVSQLP- 1497
Cdd:PHA03247 2851 PLGGSvapGGDVRRRPPSRSPAAKPAAPARPPVRRlarpavsRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPq 2930
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1958659049 1498 ------GRPKSPLSKMAQ-RPYQMPQLPVAVPQQGlRLQPAKAQIVRSNQPSSA 1544
Cdd:PHA03247 2931 ppppppPRPQPPLAPTTDpAGAGEPSGAVPQPWLG-ALVPGRVAVPRFRVPQPA 2983
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
1010-1102 |
7.89e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 44.49 E-value: 7.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1010 GRTPLMMAASEGHLGTVD--FLLAQGASIALMDKE------------GLTALSWACLKGHLSVVRSLVDNGAATdHADKN 1075
Cdd:cd21882 26 GKTCLHKAALNLNDGVNEaiMLLLEAAPDSGNPKElvnapctdefyqGQTALHIAIENRNLNLVRLLVENGADV-SARAT 104
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1958659049 1076 GRT--------------PLDLAAFYGDAEVVQFLVDHGAMI 1102
Cdd:cd21882 105 GRFfrkspgnlfyfgelPLSLAACTNQEEIVRLLLENGAQP 145
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
1059-1129 |
8.02e-04 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 44.50 E-value: 8.02e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958659049 1059 VRSLVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGcRNTSVVVTLL 1129
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEE-NGFREVVQLL 167
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
1062-1116 |
1.12e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 38.87 E-value: 1.12e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 1062 LVDNG-AATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRA 1116
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
1359-1562 |
1.30e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.87 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1359 GLPVIQSPPSSPAHRDSAYISSSPLGSHQVFDF-------RSNSSVGSPTRQGYQSTSPALSPTHQNSHYRPSPPHTSPA 1431
Cdd:pfam09770 164 GVAPKKAAAPAPAPQPAAQPASLPAPSRKMMSLeeveaamRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1432 HQGASYRFSPPPVGGQGkeypsPPPSPLRRgPQYRASPPAESMSiyrsQSGSPVRYQQEANVSQLPgrpksplSKMAQRP 1511
Cdd:pfam09770 244 QQPQQQPQQPQQHPGQG-----HPVTILQR-PQSPQPDPAQPSI----QPQAQQFHQQPPPVPVQP-------TQILQNP 306
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1958659049 1512 YQMPQLPVAVPQQGlrlqpakaQIVRSNQPSSAVHSSTVIPTGAYGQVAHP 1562
Cdd:pfam09770 307 NRLSAARVGYPQNP--------QPGVQPAPAHQAHRQQGSFGRQAPIITHP 349
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
1009-1036 |
1.31e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 37.95 E-value: 1.31e-03
10 20
....*....|....*....|....*...
gi 1958659049 1009 QGRTPLMMAASEGHLGTVDFLLAQGASI 1036
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
771-835 |
1.42e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 43.33 E-value: 1.42e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958659049 771 PNIKVSRLLILGGANINYrTEVLNNAPILCVQSHLGyTEMVALLLEFGANVDASSESGLTPLGYA 835
Cdd:PHA02878 179 KDQRLTELLLSYGANVNI-PDKTNNSPLHHAVKHYN-KPIVHILLENGASTDARDKCGNTPLHIS 241
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
944-1096 |
1.44e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 43.33 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 944 GETALTAAA---GRGKLDVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGH-----------WQIVDLLLTHGADVNMA--- 1006
Cdd:cd21882 26 GKTCLHKAAlnlNDGVNEAIMLLLEAAPDSGNPKELVNAPCTDEFYQGQtalhiaienrnLNLVRLLVENGADVSARatg 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1007 ---DKQGRT-------PLMMAASEGHLGTVDFLL---AQGASIALMDKEGLTALSWACLKGHLSVVRS---------LVD 1064
Cdd:cd21882 106 rffRKSPGNlfyfgelPLSLAACTNQEEIVRLLLengAQPAALEAQDSLGNTVLHALVLQADNTPENSafvcqmynlLLS 185
|
170 180 190
....*....|....*....|....*....|....*....
gi 1958659049 1065 NGAATDH-------ADKNGRTPLDLAAFYGDAEVVQFLV 1096
Cdd:cd21882 186 YGAHLDPtqqleeiPNHQGLTPLKLAAVEGKIVMFQHIL 224
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
773-881 |
1.67e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 43.06 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 773 IKVSRLLILGganiNYRTEVL---NNAPiLCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCK 849
Cdd:PHA02875 82 KAVEELLDLG----KFADDVFykdGMTP-LHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLID 156
|
90 100 110
....*....|....*....|....*....|..
gi 1958659049 850 KRAKVDHLDKNGQCALVHAALRGHLEVVKFLI 881
Cdd:PHA02875 157 HKACLDIEDCCGCTPLIIAMAKGDIAICKMLL 188
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1075-1100 |
1.84e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 37.62 E-value: 1.84e-03
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
799-883 |
2.80e-03 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 42.58 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 799 LCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYAAAAGFLSIVVLLCKKRAKVDHLDKNGQCALVHAALRGHLEVVK 878
Cdd:PTZ00322 86 LCQLAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165
|
....*
gi 1958659049 879 FLIQC 883
Cdd:PTZ00322 166 LLSRH 170
|
|
| PHA02989 |
PHA02989 |
ankyrin repeat protein; Provisional |
956-1036 |
3.07e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222954 [Multi-domain] Cd Length: 494 Bit Score: 42.42 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 956 KLDVCRLLLEQGAAVaqpNRRGAV--PLFSTVRQGHW------QIVDLLLTHGADVNMADKQGRTPLMMAASEGHLGTVD 1027
Cdd:PHA02989 49 KIKIVKLLIDNGADV---NYKGYIetPLCAVLRNREItsnkikKIVKLLLKFGADINLKTFNGVSPIVCFIYNSNINNCD 125
|
90
....*....|..
gi 1958659049 1028 ---FLLAQGASI 1036
Cdd:PHA02989 126 mlrFLLSKGINV 137
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
944-1131 |
3.63e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 42.31 E-value: 3.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 944 GETALTAAAGRGKLDVCRLLLEqgaavaqpnrrgAVPlfstvrqghwqivDLllthgadVNMADK----QGRTPLMMAAS 1019
Cdd:cd22192 51 GETALHVAALYDNLEAAVVLME------------AAP-------------EL-------VNEPMTsdlyQGETALHIAVV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1020 EGHLGTVDFLLAQGASIA---------LMDKEGLT-----ALSWACLKGHLSVVRSLVDNGAATDHADKNGRTPLDLAAF 1085
Cdd:cd22192 99 NQNLNLVRELIARGADVVspratgtffRPGPKNLIyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVLHILVL 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958659049 1086 YGDA----EVVQFLV-----DHGAMIEHV-DYSGMRPLDRAVGCRNTSVVVTLLKK 1131
Cdd:cd22192 179 QPNKtfacQMYDLILsydkeDDLQPLDLVpNNQGLTPFKLAAKEGNIVMFQHLVQK 234
|
|
| TRPV3 |
cd22194 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ... |
912-1096 |
4.04e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a temperature-sensitive Transient Receptor Potential (TRP) ion channel that is activated by warm temperatures, synthetic small-molecule chemicals, and natural compounds from plants. TRPV3 function is regulated by physiological factors such as extracellular divalent cations and acidic pH, intracellular adenosine triphosphate, membrane voltage, and arachidonic acid. It is expressed in both neuronal and non-neuronal tissues including epidermal keratinocytes, epithelial cells in the gut, endothelial cells in blood vessels, and neurons in dorsal root ganglia and CNS. TRPV3 null mice have abnormal hair morphogenesis and compromised skin barrier function. It may play roles in inflammatory skin disorders, such as itch and pain sensation. TRPV3 is also expressed by many neuronal and non-neuronal tissues, showing that TRPV3 might play roles in other unknown cellular and physiological functions. TRPV3 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 42.05 E-value: 4.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 912 GYTEIVSYLLDLPEKDEEEVEraqinsfdslwgeTALTAAAGRGKLDvcRLLleqGAAVAQPNRRGAVPLFSTVRQGHWQ 991
Cdd:cd22194 94 GKTCLMKALLNINENTKEIVR-------------ILLAFAEENGILD--RFI---NAEYTEEAYEGQTALNIAIERRQGD 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 992 IVDLLLTHGADVNMADKQ--------------GRTPLMMAASEGHLGTVDFLLAQGAS-IALMDKEG---LTALSWAC-- 1051
Cdd:cd22194 156 IVKLLIAKGADVNAHAKGvffnpkykhegfyfGETPLALAACTNQPEIVQLLMEKESTdITSQDSRGntvLHALVTVAed 235
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1958659049 1052 LKGHLSVVRSLVDNgAATDHADKN--------GRTPLDLAAFYGDAEVVQFLV 1096
Cdd:cd22194 236 SKTQNDFVKRMYDM-ILLKSENKNletirnneGLTPLQLAAKMGKAEILKYIL 287
|
|
| TPR_12 |
pfam13424 |
Tetratricopeptide repeat; |
1171-1243 |
4.86e-03 |
|
Tetratricopeptide repeat;
Pssm-ID: 315987 [Multi-domain] Cd Length: 77 Bit Score: 37.75 E-value: 4.86e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958659049 1171 GDMFYKKGKVKEAAQRYQYALKKFpREGFGEDlktfRELKVSLLLNLSRCRRKMNDFGMAEEFATKALELKPK 1243
Cdd:pfam13424 10 AAVLRRLGRYDEALELLEKALEIA-RRLLGPD----HPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
1010-1036 |
5.37e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 36.08 E-value: 5.37e-03
10 20
....*....|....*....|....*..
gi 1958659049 1010 GRTPLMMAASEGHLGTVDFLLAQGASI 1036
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADI 28
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
778-835 |
6.30e-03 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 36.56 E-value: 6.30e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1958659049 778 LLILGGANINYRTEVLNNApiLCVQSHLGYTEMVALLLEFGANVDASSESGLTPLGYA 835
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTP--LHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
1054-1141 |
7.38e-03 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 41.10 E-value: 7.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1054 GHLSVVRSLVDN-GAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCRNTSVVVTLLKKG 1132
Cdd:PHA02874 12 GDIEAIEKIIKNkGNCINISVDETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNG 91
|
....*....
gi 1958659049 1133 AKIGCQTLP 1141
Cdd:PHA02874 92 VDTSILPIP 100
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1414-1558 |
7.84e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.21 E-value: 7.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958659049 1414 PTHQNSHYRPSPPHTSPAHQGASYRFSPPPVGGQGKEYPSPPPSPLRR--GPQYRASPPAESMSIYRSQSGSPVRYQQEA 1491
Cdd:PHA03378 669 IGHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRpaAATGRARPPAAAPGRARPPAAAPGRARPPA 748
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958659049 1492 NVSQLPGRPKSPLSKM--------AQRPYQMPQLPvAVPQQGLRLQPAKAQivrsnQPSSAVHSSTVIPTGAYGQ 1558
Cdd:PHA03378 749 AAPGRARPPAAAPGRArppaaapgAPTPQPPPQAP-PAPQQRPRGAPTPQP-----PPQAGPTSMQLMPRAAPGQ 817
|
|
| |
