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Conserved domains on  [gi|1958668998|ref|XP_038945472|]
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breast cancer type 2 susceptibility protein homolog isoform X6 [Rattus norvegicus]

Protein Classification

BRCA2 domain-containing protein( domain architecture ID 10457562)

BRCA2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1200-1228 6.45e-08

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 50.14  E-value: 6.45e-08
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1200 EFGGFCSALGTKLSVSNEALRKAMKLFSD 1228
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1408-1436 2.01e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.98  E-value: 2.01e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1408 FNISFQTASGKNIRVSKESLNKSVNILDQ 1436
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1942-1970 3.47e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.21  E-value: 3.47e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1942 TYGIFSTASGKAVQVSDASLEKARQVFSE 1970
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1641-1669 1.35e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 43.59  E-value: 1.35e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1641 SALACYTGDSRKTCVGESSLSKGKKWLRE 1669
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 987-1015 4.99e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 4.99e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998  987 FGGSFRTASNKEIKLSEDNVKKSKMFFKD 1015
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1508-1534 5.45e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


:

Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 5.45e-05
                           10        20
                   ....*....|....*....|....*..
gi 1958668998 1508 LSFHTASGKKVKIMQESLDKVKNLFDE 1534
Cdd:pfam00634    3 LGFQTASGKKISVSEESLQKAKKLFRD 29
 
Name Accession Description Interval E-value
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1200-1228 6.45e-08

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 50.14  E-value: 6.45e-08
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1200 EFGGFCSALGTKLSVSNEALRKAMKLFSD 1228
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1408-1436 2.01e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.98  E-value: 2.01e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1408 FNISFQTASGKNIRVSKESLNKSVNILDQ 1436
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1942-1970 3.47e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.21  E-value: 3.47e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1942 TYGIFSTASGKAVQVSDASLEKARQVFSE 1970
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1641-1669 1.35e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 43.59  E-value: 1.35e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1641 SALACYTGDSRKTCVGESSLSKGKKWLRE 1669
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 987-1015 4.99e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 4.99e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998  987 FGGSFRTASNKEIKLSEDNVKKSKMFFKD 1015
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1508-1534 5.45e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 5.45e-05
                           10        20
                   ....*....|....*....|....*..
gi 1958668998 1508 LSFHTASGKKVKIMQESLDKVKNLFDE 1534
Cdd:pfam00634    3 LGFQTASGKKISVSEESLQKAKKLFRD 29
 
Name Accession Description Interval E-value
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1200-1228 6.45e-08

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 50.14  E-value: 6.45e-08
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1200 EFGGFCSALGTKLSVSNEALRKAMKLFSD 1228
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1408-1436 2.01e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.98  E-value: 2.01e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1408 FNISFQTASGKNIRVSKESLNKSVNILDQ 1436
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1942-1970 3.47e-07

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 48.21  E-value: 3.47e-07
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1942 TYGIFSTASGKAVQVSDASLEKARQVFSE 1970
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1641-1669 1.35e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 43.59  E-value: 1.35e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998 1641 SALACYTGDSRKTCVGESSLSKGKKWLRE 1669
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 987-1015 4.99e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 4.99e-05
                           10        20
                   ....*....|....*....|....*....
gi 1958668998  987 FGGSFRTASNKEIKLSEDNVKKSKMFFKD 1015
Cdd:pfam00634    1 SFLGFQTASGKKISVSEESLQKAKKLFRD 29
BRCA2 pfam00634
BRCA2 repeat; The alignment covers only the most conserved region of the repeat.
 1508-1534 5.45e-05

BRCA2 repeat; The alignment covers only the most conserved region of the repeat.


Pssm-ID: 459881  Cd Length: 29  Bit Score: 42.05  E-value: 5.45e-05
                           10        20
                   ....*....|....*....|....*..
gi 1958668998 1508 LSFHTASGKKVKIMQESLDKVKNLFDE 1534
Cdd:pfam00634    3 LGFQTASGKKISVSEESLQKAKKLFRD 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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