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Conserved domains on  [gi|1958747411|ref|XP_038953961|]
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transcriptional repressor CTCF isoform X2 [Rattus norvegicus]

Protein Classification

transcriptional repressor CTCF( domain architecture ID 12159901)

transcriptional repressor CTCF acts as a chromatin binding factor that binds to DNA sequence specific sites and regulates the 3D structure of chromatin

CATH:  3.30.160.60
Gene Ontology:  GO:0003700|GO:0008270|GO:0003677
PubMed:  11361095|22803940|11179890|12665246|10940247
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
366-500 3.12e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.55  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 366 LKRHIRS--HTGE--RPFQC--SLCSYASRDTYKLKRHMRTHSGEKPYECYI--CHARFTQSGTMK---MHILQKHTENV 434
Cdd:COG5048   305 LTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLNNEppqSLQQYKDLKND 384

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958747411 435 AKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCR--YCDAVFHERYALIQHQKSHKNEKRFKCDQC 500
Cdd:COG5048   385 KKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL 452
zf-H2C2_2 pfam13465
Zinc-finger double domain;
280-305 5.55e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 5.55e-05
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 280 NLDRHMKSHTDERPHKCHLCGRAFRT 305
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
509-534 1.51e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.51e-04
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 509 HMIMHKRTHTGEKPYACSHCDKTFRQ 534
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
309-333 4.14e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.14e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 309 LRNHLNTHTGTRPHKCPDCDMAFVT 333
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
351-375 8.10e-04

C2H2-type zinc-finger domain;


:

Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 37.14  E-value: 8.10e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 351 FKCSMCDYASVEVSKLKRHIRSHTG 375
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
266-289 5.66e-03

C2H2-type zinc-finger domain;


:

Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 34.83  E-value: 5.66e-03
                          10        20
                  ....*....|....*....|....
gi 1958747411 266 FQCELCSYTCPRRSNLDRHMKSHT 289
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHT 24
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
366-500 3.12e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.55  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 366 LKRHIRS--HTGE--RPFQC--SLCSYASRDTYKLKRHMRTHSGEKPYECYI--CHARFTQSGTMK---MHILQKHTENV 434
Cdd:COG5048   305 LTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLNNEppqSLQQYKDLKND 384

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958747411 435 AKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCR--YCDAVFHERYALIQHQKSHKNEKRFKCDQC 500
Cdd:COG5048   385 KKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL 452
zf-H2C2_2 pfam13465
Zinc-finger double domain;
394-418 8.29e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 8.29e-06
                          10        20
                  ....*....|....*....|....*
gi 1958747411 394 LKRHMRTHSGEKPYECYICHARFTQ 418
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
280-305 5.55e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 5.55e-05
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 280 NLDRHMKSHTDERPHKCHLCGRAFRT 305
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
509-534 1.51e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.51e-04
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 509 HMIMHKRTHTGEKPYACSHCDKTFRQ 534
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 468-500 1.78e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 1.78e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1958747411 468 KCRYCDAVFHERYALIQHQKShkneKRFKCDQC 500
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQKA----KHFKCHIC 31
zf-H2C2_2 pfam13465
Zinc-finger double domain;
309-333 4.14e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.14e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 309 LRNHLNTHTGTRPHKCPDCDMAFVT 333
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
351-375 8.10e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 37.14  E-value: 8.10e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 351 FKCSMCDYASVEVSKLKRHIRSHTG 375
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
266-289 5.66e-03

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 34.83  E-value: 5.66e-03
                          10        20
                  ....*....|....*....|....
gi 1958747411 266 FQCELCSYTCPRRSNLDRHMKSHT 289
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHT 24
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
366-500 3.12e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.55  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 366 LKRHIRS--HTGE--RPFQC--SLCSYASRDTYKLKRHMRTHSGEKPYECYI--CHARFTQSGTMK---MHILQKHTENV 434
Cdd:COG5048   305 LTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFSPLLNNEppqSLQQYKDLKND 384

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958747411 435 AKFHCPHCDTVIARKSDLGVHLRKQHSYIEQGKKCR--YCDAVFHERYALIQHQKSHKNEKRFKCDQC 500
Cdd:COG5048   385 KKSETLSNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSIL 452
zf-H2C2_2 pfam13465
Zinc-finger double domain;
394-418 8.29e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 8.29e-06
                          10        20
                  ....*....|....*....|....*
gi 1958747411 394 LKRHMRTHSGEKPYECYICHARFTQ 418
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
280-305 5.55e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 5.55e-05
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 280 NLDRHMKSHTDERPHKCHLCGRAFRT 305
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
509-534 1.51e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.51e-04
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 509 HMIMHKRTHTGEKPYACSHCDKTFRQ 534
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 468-500 1.78e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.62  E-value: 1.78e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1958747411 468 KCRYCDAVFHERYALIQHQKShkneKRFKCDQC 500
Cdd:cd20908     3 WCYYCDREFDDEKILIQHQKA----KHFKCHIC 31
zf-H2C2_2 pfam13465
Zinc-finger double domain;
366-387 2.72e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.72e-04
                          10        20
                  ....*....|....*....|..
gi 1958747411 366 LKRHIRSHTGERPFQCSLCSYA 387
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKS 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
265-428 3.00e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 3.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 265 TFQC--ELCSYTCPRRSNLDRHMKSHTDERPHKCHlcgrafrtvtlLRNHLNTHTGtrphkcpdcdmAFVTSGELVRHRR 342
Cdd:COG5048   321 PFSCpySLCGKLFSRNDALKRHILLHTSISPAKEK-----------LLNSSSKFSP-----------LLNNEPPQSLQQY 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 343 YKHTHEKPFKCSM--CDYASVEVSKLKRHIRSHTGERP--FQCSLCSYASRDTYKLKRHMRTHSgEKPYECYICHARFTQ 418
Cdd:COG5048   379 KDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHT-NHAPLLCSILKSFRR 457

                         170
                  ....*....|
gi 1958747411 419 SGTMKMHILQ 428
Cdd:COG5048   458 DLDLSNHGKD 467
zf-H2C2_2 pfam13465
Zinc-finger double domain;
309-333 4.14e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.14e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 309 LRNHLNTHTGTRPHKCPDCDMAFVT 333
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
290-573 4.17e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.53  E-value: 4.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 290 DERPHKCHLCGRAFRTVTLLRNHLNTHTGTRPHKCPD--CDMAFVTSGELVRHRRYKHTHeKPFKCSMCDYAS-VEVSKL 366
Cdd:COG5048    30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNN-PSDLNSKSLPLSnSKASSS 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 367 KRHIRSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARF--------TQSGTMKMHILQKHTENVAKFH 438
Cdd:COG5048   109 SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSvntpqsnsLHPPLPANSLSKDPSSNLSLLI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958747411 439 CP--HCDTVIARKSDLGVHLRK-QHSYIEQGK-------KCRYCDAVFHERYALIQHQKSHKNEKRFKCDQCDYACRQER 508
Cdd:COG5048   189 SSnvSTSIPSSSENSPLSSSYSiPSSSSDQNLensssslPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTA 268

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958747411 509 HMIMHKRTHTGE-------KPYACSHCDKTFRQKQLLDMHFKRYHDPNFVPAAFVC--SKCGKTFTRRNTMARH 573
Cdd:COG5048   269 SSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSVNHSGESLKPFSCpySLCGKLFSRNDALKRH 342
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
351-375 8.10e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 37.14  E-value: 8.10e-04
                          10        20
                  ....*....|....*....|....*
gi 1958747411 351 FKCSMCDYASVEVSKLKRHIRSHTG 375
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
DiS_P_DiS pfam06750
Bacterial Peptidase A24 N-terminal domain; This family is found at the N-terminus of the ...
 438-483 4.30e-03

Bacterial Peptidase A24 N-terminal domain; This family is found at the N-terminus of the pre-pilin peptidases (pfam01478). It's function has not been specifically determined; however some of the family have been characterized as bifunctional, and this domain may contain the N-methylation activity (EC:2.1.1.-). It consists of an intracellular region between a pair of transmembrane. This region contains an invariant proline and two almost fully conserved disulphide bridges - hence the name DiS-P-DiS. The cysteines have been shown to be essential to the overall function of the enzyme in, but their role was incorrectly ascribed.


Pssm-ID: 462001  Cd Length: 84  Bit Score: 36.65  E-value: 4.30e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1958747411 438 HCPHCDTVIaRKSDLGVHLrkqhSYIEQGKKCRYCDAVFHERYALI 483
Cdd:pfam06750  29 HCPSCGHRL-RWYDNIPVL----SWLLLRGRCRYCGAKISIRYPLV 69
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
266-289 5.66e-03

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 34.83  E-value: 5.66e-03
                          10        20
                  ....*....|....*....|....
gi 1958747411 266 FQCELCSYTCPRRSNLDRHMKSHT 289
Cdd:pfam13909   1 YKCSQCDYSTAWKSNLKRHLRKHT 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
481-506 8.37e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 8.37e-03
                          10        20
                  ....*....|....*....|....*.
gi 1958747411 481 ALIQHQKSHKNEKRFKCDQCDYACRQ 506
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SF2_C_priA cd18804
C-terminal helicase domain of ATP-dependent helicase PriA; PriA, also known as replication ...
 265-335 8.51e-03

C-terminal helicase domain of ATP-dependent helicase PriA; PriA, also known as replication factor Y or primosomal protein N', is a 3'-->5' DNA helicase that acts to remodel stalled replication forks and as a specificity factor for origin-independent assembly of a new replisome at the stalled fork. PriA is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.


Pssm-ID: 350191 [Multi-domain]  Cd Length: 238  Bit Score: 38.38  E-value: 8.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958747411 265 TFQCELCSYTcPRRSNLDRHMKSHTDERPHKCHLCGRAFRTvtllrnhlnthtgtrPHKCPDC---DMAFVTSG 335
Cdd:cd18804    45 SVLCRDCGYV-PECPNCDVSMTYHKSTNKLKCHYCGYQEPI---------------PKQCPECgseDLVFKGIG 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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