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Conserved domains on  [gi|1958760470|ref|XP_038960432|]
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CCN family member 5 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 194-237 1.55e-15

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


:

Pssm-ID: 465952  Cd Length: 44  Bit Score: 68.51  E-value: 1.55e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958760470 194 CPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRRLCLPRPC 237
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
IGFBP pfam00219
Insulin-like growth factor binding protein;
26-78 5.07e-08

Insulin-like growth factor binding protein;


:

Pssm-ID: 459717  Cd Length: 53  Bit Score: 48.48  E-value: 5.07e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958760470  26 CRTPCT---CPWTPPQCPQGVplVLDGCGCCKVCARRLGESCDHLH-VCDPsqGLVC 78
Cdd:pfam00219   1 CPPPCDperCPPPPPGCPAGV--VLDGCGCCKVCARQEGEPCGVYTpPCGK--GLRC 53
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 100-159 5.48e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member smart00214:

Pssm-ID: 450195  Cd Length: 59  Bit Score: 37.11  E-value: 5.48e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958760470  100 CEVNGRRYLDGETFKPNCRVLCRCDDGGF-TCLPLCSEdvrlPSWDCPRPKRIQVPGRCCP 159
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECP----PPPDCPNPERVKPPGECCP 57
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 194-237 1.55e-15

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 68.51  E-value: 1.55e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958760470 194 CPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRRLCLPRPC 237
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
IGFBP pfam00219
Insulin-like growth factor binding protein;
26-78 5.07e-08

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 48.48  E-value: 5.07e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958760470  26 CRTPCT---CPWTPPQCPQGVplVLDGCGCCKVCARRLGESCDHLH-VCDPsqGLVC 78
Cdd:pfam00219   1 CPPPCDperCPPPPPGCPAGV--VLDGCGCCKVCARQEGEPCGVYTpPCGK--GLRC 53
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 28-64 7.79e-05

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 40.14  E-value: 7.79e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1958760470   28 TPCTCPWTPPQCPQGVplVLDGCGCCKVCARRLGESC 64
Cdd:smart00121   7 DPARCPPCPPGCAELV--RLDGCGCCPVCARQEGEPC 41
VWC smart00214
von Willebrand factor (vWF) type C domain;
100-159 5.48e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 37.11  E-value: 5.48e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958760470  100 CEVNGRRYLDGETFKPNCRVLCRCDDGGF-TCLPLCSEdvrlPSWDCPRPKRIQVPGRCCP 159
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECP----PPPDCPNPERVKPPGECCP 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 100-160 8.28e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 36.63  E-value: 8.28e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958760470 100 CEVNGRRYLDGETFKPNCRVLCRCDDGGFTClplcsEDVRLPSWDCPRPKRIQVPGRCCPE 160
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLC-----DKIICPPLDCPNPRLEIPPGECCPV 56
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 194-237 1.55e-15

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 68.51  E-value: 1.55e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958760470 194 CPNWSTAWGPCSTTCGLGIATRVSNQNRFCQLEIQRRLCLPRPC 237
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
IGFBP pfam00219
Insulin-like growth factor binding protein;
26-78 5.07e-08

Insulin-like growth factor binding protein;


Pssm-ID: 459717  Cd Length: 53  Bit Score: 48.48  E-value: 5.07e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958760470  26 CRTPCT---CPWTPPQCPQGVplVLDGCGCCKVCARRLGESCDHLH-VCDPsqGLVC 78
Cdd:pfam00219   1 CPPPCDperCPPPPPGCPAGV--VLDGCGCCKVCARQEGEPCGVYTpPCGK--GLRC 53
IB smart00121
Insulin growth factor-binding protein homologues; High affinity binding partners of ...
 28-64 7.79e-05

Insulin growth factor-binding protein homologues; High affinity binding partners of insulin-like growth factors.


Pssm-ID: 197525  Cd Length: 75  Bit Score: 40.14  E-value: 7.79e-05
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 1958760470   28 TPCTCPWTPPQCPQGVplVLDGCGCCKVCARRLGESC 64
Cdd:smart00121   7 DPARCPPCPPGCAELV--RLDGCGCCPVCARQEGEPC 41
VWC smart00214
von Willebrand factor (vWF) type C domain;
100-159 5.48e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 37.11  E-value: 5.48e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958760470  100 CEVNGRRYLDGETFKPNCRVLCRCDDGGF-TCLPLCSEdvrlPSWDCPRPKRIQVPGRCCP 159
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGTTvLCDPVECP----PPPDCPNPERVKPPGECCP 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 100-160 8.28e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 36.63  E-value: 8.28e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958760470 100 CEVNGRRYLDGETFKPNCRVLCRCDDGGFTClplcsEDVRLPSWDCPRPKRIQVPGRCCPE 160
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLC-----DKIICPPLDCPNPRLEIPPGECCPV 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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