NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958760879|ref|XP_038960576|]
View 

protein FAM210B, mitochondrial isoform X2 [Rattus norvegicus]

Protein Classification

FAM210 family protein( domain architecture ID 7108)

FAM210 family protein is a DUF1279 domain-containing protein; similar to Saccharomyces cerevisiae N-terminal acetyltransferase 2 that may be involved in N-terminal acetylation of proteins

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FAM210A-B_dom super family cl06121
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-119 1.79e-11

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


The actual alignment was detected with superfamily member pfam06916:

Pssm-ID: 429191  Cd Length: 88  Bit Score: 56.88  E-value: 1.79e-11
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1958760879  85 QQLKKVFQEYGAVGVSLHIGISLVSLGIFYTIVSS 119
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSS 35
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-119 1.79e-11

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 56.88  E-value: 1.79e-11
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1958760879  85 QQLKKVFQEYGAVGVSLHIGISLVSLGIFYTIVSS 119
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSS 35
 
Name Accession Description Interval E-value
FAM210A-B_dom pfam06916
FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, ...
 85-119 1.79e-11

FAM210A/B-like domain; This domain is found in mitochondrial proteins, including FAM210A and B, which contains a transmembrane peptide. Its function is not clear. FAM210A, a protein essential in maintaining skeletal muscle structure and strength, interacts with mitochondrial translation elongation factor EF-Tu and promotes mitochondrial protein expression. In FAM210A, this domain is responsible for binding EF-Tu. FAM210B plays a role in erythroid differentiation and is involved in cell proliferation and tumour cell growth suppression.


Pssm-ID: 429191  Cd Length: 88  Bit Score: 56.88  E-value: 1.79e-11
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1958760879  85 QQLKKVFQEYGAVGVSLHIGISLVSLGIFYTIVSS 119
Cdd:pfam06916   1 QRLKELFKKYGYVALGVHFSISLASFGIFYLLVSS 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH