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Conserved domains on  [gi|1958775023|ref|XP_038965316|]
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junctophilin-1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642    93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642   167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642   214 --------ADGDR------------------------------------------------------------------- 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642   219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                         330
                  ....*....|.
gi 1958775023 323 DGSKEEGKYKN 333
Cdd:COG4642   261 DGSVYEGEWKN 271
PspC_subgroup_2 super family cl41463
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


The actual alignment was detected with superfamily member NF033839:

Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839  308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839  386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775023 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839  456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642    93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642   167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642   214 --------ADGDR------------------------------------------------------------------- 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642   219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                         330
                  ....*....|.
gi 1958775023 323 DGSKEEGKYKN 333
Cdd:COG4642   261 DGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.92e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.14  E-value: 1.92e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185   24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775023  81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185  101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 8.85e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 8.85e-05
                          10        20
                  ....*....|....*....|...
gi 1958775023 304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839  308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839  386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775023 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839  456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.68e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.68e-04
                           10        20
                   ....*....|....*....|.
gi 1958775023  303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
3-333 7.81e-24

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 101.57  E-value: 7.81e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   3 GGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETkgkwmy 82
Cdd:COG4642    93 GGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPHGQGTLT------ 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  83 rgeWSHGfkgrygvrqslctpARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQSvpygmatvirsplrts 162
Cdd:COG4642   167 ---YADG--------------DRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQGTYTY---------------- 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 163 laslrseqSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskrssvrsd 242
Cdd:COG4642   214 --------ADGDR------------------------------------------------------------------- 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 243 aamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFP 322
Cdd:COG4642   219 --------------------------------------YEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMTYA 260

                         330
                  ....*....|.
gi 1958775023 323 DGSKEEGKYKN 333
Cdd:COG4642   261 DGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
2-143 1.77e-23

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 100.42  E-value: 1.77e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   2 TGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGqGEYSGSWSHG-FEVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKW 80
Cdd:COG4642   138 GGGIYTFPNGDVYEGEFKNGKPHGQGTLTYADG-DRYEGEFKNGkRHGQGTLTYANGDVYEGEFKNGQRHG-----QGTY 211

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958775023  81 MyrgeWSHGFkgrygvrqslctpaRYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:COG4642   212 T----YADGD--------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGT 256
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 4-143 1.92e-21

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 99.14  E-value: 1.92e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   4 GRFDFDDGGTYCGGWEEGKAHGHGICTGPKG---QGEYSGSWSHGFevvGGYTWPSGNTYQGYWAQGKRHGLGVETKGKW 80
Cdd:PLN03185   24 GKYLWSDGCMYEGEWRRGMRHGNGKISWPSGatyEGEFSGGYMHGS---GTYTGTDGTTYKGRWRLNLKHGLGYQRYPNG 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775023  81 -MYRGEWSHGFK---GRYgvrqSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGV 143
Cdd:PLN03185  101 dVFEGSWIQGLQegpGKY----TWANGNVYLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGV 163
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
9-336 6.96e-20

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 90.02  E-value: 6.96e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023   9 DDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWAQGKRHGLGVETKGKWM-YRGEWS 87
Cdd:COG4642    41 PGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGgGGGVLE 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  88 HGFKGRYGVRQS--------LCTPA---RYEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGVRQsvpygmatvir 156
Cdd:COG4642   121 GDDGGGYGGGTAdggrggggIYTFPngdVYEGEFKNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLT----------- 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 157 splrtslaslrseQSNGSVlheaaaaaadnpagtrggfvlnfhadtelgkkksglfrrgsllgsmklrkseskssisskr 236
Cdd:COG4642   190 -------------YANGDV------------------------------------------------------------- 195

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 237 ssvrsdaamsrisssdanstisfgdvdcdfcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGY 316
Cdd:COG4642   196 --------------------------------------------YEGEFKNGQRHGQGTYTYADGDRYEGEFKNGKRHGQ 231

                         330       340
                  ....*....|....*....|
gi 1958775023 317 GCTVFPDGSKEEGKYKNNIL 336
Cdd:COG4642   232 GTLTYADGDRYEGEFKNGKR 251
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 38-150 1.17e-10

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 64.85  E-value: 1.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  38 YSGSWSHGF-EVVGGYTWPSGNTYQGYWAQGKRHGlgvetKGKWMyrgeWSHGfkgrygvrqslctpARYEGTWSNGLQD 116
Cdd:PLN03185   11 YSGSLLGNVpEGPGKYLWSDGCMYEGEWRRGMRHG-----NGKIS----WPSG--------------ATYEGEFSGGYMH 67

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1958775023 117 GYGVETYGDGGTYQGQWAGGMRHGYGvRQSVPYG 150
Cdd:PLN03185   68 GSGTYTGTDGTTYKGRWRLNLKHGLG-YQRYPNG 100
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-325 1.75e-05

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 47.91  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 106 YEGTWSNGLQDGYGVETYGDGGTYQGQWAGGMRHGYGvrqsvpygmatVIRSPlrtSLASLRSEQSNGsVLHEAAAAAAD 185
Cdd:PLN03185   11 YSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNG-----------KISWP---SGATYEGEFSGG-YMHGSGTYTGT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 186 NPAGTRGGFVLNFhadtelgkkKSGLFRRGSLLGSMklrkseskssisskrssvRSDAAMSRISSSDANSTISFGDVdcd 265
Cdd:PLN03185   76 DGTTYKGRWRLNL---------KHGLGYQRYPNGDV------------------FEGSWIQGLQEGPGKYTWANGNV--- 125

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 266 fcpvedhvdatttetYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGS 325
Cdd:PLN03185  126 ---------------YLGDMKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGG 170
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 5.17e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 44.29  E-value: 5.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775023 283 GEWKNDKRNGFGISERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849    83 GTYKNGKLEGEWKEYYENGkLKSEGNYKNGKLHGEWKEYYENGKlKEEGNYKNGKKD 139
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 304-326 8.85e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 39.70  E-value: 8.85e-05
                          10        20
                  ....*....|....*....|...
gi 1958775023 304 YEGEWANNKRHGYGCTVFPDGSK 326
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-332 1.97e-04

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 44.82  E-value: 1.97e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958775023 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYK 332
Cdd:PLN03185   56 TYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWI 108
PspC_subgroup_2 NF033839
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ...
 410-638 2.76e-04

pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.


Pssm-ID: 468202 [Multi-domain]  Cd Length: 557  Bit Score: 43.99  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 410 RELSPDFYQPGPDYIKQRFQEGVDIKENPEEKVPEKPPSP-KESPHFYRKGTTPprSPEASP-----KQSHSPQPSSPKS 483
Cdd:NF033839  308 KEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKPEVKPQLeTPKPEVKPQPEKP--KPEVKPqpekpKPEVKPQPETPKP 385

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023 484 MKKQNPSSGARLSHDKRNTAEEQVVAIVNKPLMSKAPSKELGATVSKYSgrhyvPNPSNGELHSQYHGyyvklNTPQHPP 563
Cdd:NF033839  386 EVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQ-----PEKPKPEVKPQPEK-----PKPEVKP 455

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958775023 564 EDREDDSGVGQSSSALVPRPSPNKWSPPKSVTKPVAKESKTEPKAKKSELAIPKNTAS---NDTCPPLEKEANSGPNS 638
Cdd:NF033839  456 QPETPKPEVKPQPEKPKPEVKPQPEKPKPDNSKPQADDKKPSTPNNLSKDKQPSNQAStneKATNKPKKSLPSTGSIS 533
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 106-128 3.01e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.16  E-value: 3.01e-04
                          10        20
                  ....*....|....*....|...
gi 1958775023 106 YEGTWSNGLQDGYGVETYGDGGT 128
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
303-323 4.68e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.71  E-value: 4.68e-04
                           10        20
                   ....*....|....*....|.
gi 1958775023  303 KYEGEWANNKRHGYGCTVFPD 323
Cdd:smart00698   2 RYEGEWRNGKRHGRGVYTYAN 22
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 280-335 1.02e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.51  E-value: 1.02e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958775023 280 TYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKYKNNI 335
Cdd:PLN03185   33 MYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
283-337 1.04e-03

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 40.44  E-value: 1.04e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958775023 283 GEWKNDKRNGFGISERSNG-MKYEGEWANNKRHGYGCTVFPDGS-KEEGKYKNNILV 337
Cdd:COG2849   107 GNYKNGKLHGEWKEYYENGkLKEEGNYKNGKKDGVWKYYDENGKlVKEEEYKNGKKV 163
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 279-331 1.33e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 42.13  E-value: 1.33e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1958775023 279 ETYMGEWKNDKRNGFGISERSNGMKYEGEWANNKRHGYGCTVFPDGSKEEGKY 331
Cdd:PLN03185    9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEF 61
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 55-142 1.66e-03

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 41.74  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958775023  55 PSGNTYQGYWaqgkrHGLGVETKGKWMyrgeWSHGfkgrygvrqslCTparYEGTWSNGLQDGYGVETYGDGGTYQGQWA 134
Cdd:PLN03185    6 SNGDFYSGSL-----LGNVPEGPGKYL----WSDG-----------CM---YEGEWRRGMRHGNGKISWPSGATYEGEFS 62


                  ....*...
gi 1958775023 135 GGMRHGYG 142
Cdd:PLN03185   63 GGYMHGSG 70
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
104-125 9.98e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 33.85  E-value: 9.98e-03
                           10        20
                   ....*....|....*....|..
gi 1958775023  104 ARYEGTWSNGLQDGYGVETYGD 125
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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