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Conserved domains on  [gi|1958785842|ref|XP_038969155|]
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protein TALPID3 isoform X1 [Rattus norvegicus]

Protein Classification

TALPID3 domain-containing protein( domain architecture ID 12173090)

TALPID3 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
116-1357 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


:

Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1722.42  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  116 DIFISQYATGQKDALRTVLKQKAQSTPAFKAVKVHLLEDMSTEKNTVAQDTETPPNRIDPATTVAAATAAAIATAAPLIK 195
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  196 VQSDLEAKVNSVGELLNKLQETDKQLQRVTEHQASIQHKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQMDIQTHFIDA 275
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  276 ALKASSLQFGLS-SSRAEDKY--SGKPQHPSV----SSHNTFVSKQVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 346
Cdd:pfam15324  161 ALKAVSLQPSSVtSSRAVEKSgnSSEDESPAVgsasTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  347 GKVTKRESSIEEKENMEMYSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNFEKRDSTETLHSQRFPSCEDRG 426
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  427 TAQVPVQKYNDIVHDLSQKKKQTSDMLQV-----------------KQSPVTLRLSDHP------------------HNP 471
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQLKKEMRSLLQTadafpvpnakstrssqsSRSLSPLPTPPPPppapismppvtavslaalSSP 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  472 VMPQTTN-TRSVLKDAAKILRGVQNNKKVLEENLDAIVRAKDGAAVYSFINALATNREMSEKIRIRKKVDEWIKIISAEI 550
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  551 QDELTRKDYE-KRFDPKNQRNKKSLTM--------SRDIKANNQDKTANRSIIPRSHYQKQTQEQFTSPPVRSVPASAPQ 621
Cdd:pfam15324  481 QDELARKDYEqKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  622 ReknvrntpasapqreKNGLLKSTTTLQDEDYMFQIYGKPLYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIERVKGTKV 701
Cdd:pfam15324  561 K---------------KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKV 625
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  702 KSARTQTDFHATPLTKTDSKAQHPITtLPHAHQQCVLSPSREMPTVSGTLDGHLIPMAILLGQTQSNSDSIPPAGVLVSK 781
Cdd:pfam15324  626 KSARTQTDLHATKPVKTDSKMQHSVT-APHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSK 704
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  782 PHPVTVTTSIPPSSRKVKAGVKKPNVAVVEMKSEKKDPPQLSVQILPSVDID--SISYSSTGGSSPSPSPKEASPPPLHT 859
Cdd:pfam15324  705 PHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDsvSCSSRDSSPSPVLPSPSEASPPLIQT 784
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  860 WIQTPEFMKVDEEELPVPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYSGPSFPPVVSALRPTTDILDK 939
Cdd:pfam15324  785 WIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDK 864
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  940 VIERKETLENNLIQWVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVPGTSSGAFQLMVDAGVPVNSDMISH 1019
Cdd:pfam15324  865 VIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRH 944
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1020 FVNEALAETIAVMLADREAKKQGPAATRVSGDLSRNETNVSArvypPVATPQPTPPCSP-APLKEHVFVKTPDSSPCESD 1098
Cdd:pfam15324  945 FVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETLLPT----PVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSE 1020
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1099 QDVaSSVKEIPVEKGSD-LPVATLVSTPTRTPVTTPPPAAALTPTLSEISIDKLKFSSPELPKPWDSGDLPLDEENPNSL 1177
Cdd:pfam15324 1021 HDF-FPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSE 1099
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1178 QERLHPRAVVMSVAIDEEPESVASSAQpvPPEPAPLAPHLEDTKAPSLQQILSSGSSTPENTLS-TVTETETLDRHISEG 1256
Cdd:pfam15324 1100 QEELHPRAVVMSVARDEEPESVVLPAS--PPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEG 1177
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1257 EILLSCGQNLATKR--NGDLFLMNINDSLSTTLQDALDMEDDPPSEGQVIRRPHKKLHENAIISLLTKQEQELLVSQQA- 1333
Cdd:pfam15324 1178 EILFSYGQMLAVRAleEGGLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAv 1257
                         1290      1300
                   ....*....|....*....|....*..
gi 1958785842 1334 ---EDLDNSVGELSEGQRLVLKAAEDI 1357
Cdd:pfam15324 1258 yhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
116-1357 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1722.42  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  116 DIFISQYATGQKDALRTVLKQKAQSTPAFKAVKVHLLEDMSTEKNTVAQDTETPPNRIDPATTVAAATAAAIATAAPLIK 195
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  196 VQSDLEAKVNSVGELLNKLQETDKQLQRVTEHQASIQHKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQMDIQTHFIDA 275
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  276 ALKASSLQFGLS-SSRAEDKY--SGKPQHPSV----SSHNTFVSKQVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 346
Cdd:pfam15324  161 ALKAVSLQPSSVtSSRAVEKSgnSSEDESPAVgsasTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  347 GKVTKRESSIEEKENMEMYSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNFEKRDSTETLHSQRFPSCEDRG 426
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  427 TAQVPVQKYNDIVHDLSQKKKQTSDMLQV-----------------KQSPVTLRLSDHP------------------HNP 471
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQLKKEMRSLLQTadafpvpnakstrssqsSRSLSPLPTPPPPppapismppvtavslaalSSP 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  472 VMPQTTN-TRSVLKDAAKILRGVQNNKKVLEENLDAIVRAKDGAAVYSFINALATNREMSEKIRIRKKVDEWIKIISAEI 550
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  551 QDELTRKDYE-KRFDPKNQRNKKSLTM--------SRDIKANNQDKTANRSIIPRSHYQKQTQEQFTSPPVRSVPASAPQ 621
Cdd:pfam15324  481 QDELARKDYEqKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  622 ReknvrntpasapqreKNGLLKSTTTLQDEDYMFQIYGKPLYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIERVKGTKV 701
Cdd:pfam15324  561 K---------------KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKV 625
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  702 KSARTQTDFHATPLTKTDSKAQHPITtLPHAHQQCVLSPSREMPTVSGTLDGHLIPMAILLGQTQSNSDSIPPAGVLVSK 781
Cdd:pfam15324  626 KSARTQTDLHATKPVKTDSKMQHSVT-APHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSK 704
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  782 PHPVTVTTSIPPSSRKVKAGVKKPNVAVVEMKSEKKDPPQLSVQILPSVDID--SISYSSTGGSSPSPSPKEASPPPLHT 859
Cdd:pfam15324  705 PHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDsvSCSSRDSSPSPVLPSPSEASPPLIQT 784
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  860 WIQTPEFMKVDEEELPVPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYSGPSFPPVVSALRPTTDILDK 939
Cdd:pfam15324  785 WIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDK 864
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  940 VIERKETLENNLIQWVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVPGTSSGAFQLMVDAGVPVNSDMISH 1019
Cdd:pfam15324  865 VIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRH 944
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1020 FVNEALAETIAVMLADREAKKQGPAATRVSGDLSRNETNVSArvypPVATPQPTPPCSP-APLKEHVFVKTPDSSPCESD 1098
Cdd:pfam15324  945 FVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETLLPT----PVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSE 1020
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1099 QDVaSSVKEIPVEKGSD-LPVATLVSTPTRTPVTTPPPAAALTPTLSEISIDKLKFSSPELPKPWDSGDLPLDEENPNSL 1177
Cdd:pfam15324 1021 HDF-FPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSE 1099
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1178 QERLHPRAVVMSVAIDEEPESVASSAQpvPPEPAPLAPHLEDTKAPSLQQILSSGSSTPENTLS-TVTETETLDRHISEG 1256
Cdd:pfam15324 1100 QEELHPRAVVMSVARDEEPESVVLPAS--PPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEG 1177
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1257 EILLSCGQNLATKR--NGDLFLMNINDSLSTTLQDALDMEDDPPSEGQVIRRPHKKLHENAIISLLTKQEQELLVSQQA- 1333
Cdd:pfam15324 1178 EILFSYGQMLAVRAleEGGLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAv 1257
                         1290      1300
                   ....*....|....*....|....*..
gi 1958785842 1334 ---EDLDNSVGELSEGQRLVLKAAEDI 1357
Cdd:pfam15324 1258 yhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Name Accession Description Interval E-value
TALPID3 pfam15324
Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for ...
116-1357 0e+00

Hedgehog signalling target; TALPID3 is a family of eukaryotic proteins that are targets for Hedgehog signalling. Mutations in this gene noticed first in chickens lead to multiple abnormalities of development.


Pssm-ID: 434634 [Multi-domain]  Cd Length: 1288  Bit Score: 1722.42  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  116 DIFISQYATGQKDALRTVLKQKAQSTPAFKAVKVHLLEDMSTEKNTVAQDTETPPNRIDPATTVAAATAAAIATAAPLIK 195
Cdd:pfam15324    1 DIFISQYSAGQKDAVRAVLKQRAQSAPVFKEVKVQLLDDACSEKDAVGPEVQPSPSGIDSATTVAAATAAAIATTAPLIK 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  196 VQSDLEAKVNSVGELLNKLQETDKQLQRVTEHQASIQHKQEKLHCHDHEKQMNVFMEQHIRHLEKLQQQQMDIQTHFIDA 275
Cdd:pfam15324   81 VQSDLEAKVNSVSELLKKLQETDKQLQRVTEQQTSIQAKQEKSCCHDHEKQMNAFMEQRLRHLEKIQQQQIDIQTHLIGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  276 ALKASSLQFGLS-SSRAEDKY--SGKPQHPSV----SSHNTFVSKQVPLSE--DTDFDGQKSPLETPAPRRFAPVPVSRD 346
Cdd:pfam15324  161 ALKAVSLQPSSVtSSRAVEKSgnSSEDESPAVgsasTSHHTFAPKQAPLAEvrDTQFDRQKSPLETPAPRRFAPVPVSRD 240
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  347 GKVTKRESSIEEKENMEMYSPKGNVRLLEQVLNSNECLTRKTESSDITSLTQPKMGWNFEKRDSTETLHSQRFPSCEDRG 426
Cdd:pfam15324  241 AKISKREPPKEEKENMETSSSKGNGRLLEQILNNQDSPTRKSESSVVTSLAMATVGWQPERSRESQPLEPQSFPSSEEPE 320
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  427 TAQVPVQKYNDIVHDLSQKKKQTSDMLQV-----------------KQSPVTLRLSDHP------------------HNP 471
Cdd:pfam15324  321 TASVTVQKASDVLQDLGQLKKEMRSLLQTadafpvpnakstrssqsSRSLSPLPTPPPPppapismppvtavslaalSSP 400
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  472 VMPQTTN-TRSVLKDAAKILRGVQNNKKVLEENLDAIVRAKDGAAVYSFINALATNREMSEKIRIRKKVDEWIKIISAEI 550
Cdd:pfam15324  401 SVLQSTQpPRSMLKDAEKILRQVQNNKKVLEENLEAIIRAKDGAALHSFINALSTNRDMSEEIRIRKTVDEWIKTISKEI 480
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  551 QDELTRKDYE-KRFDPKNQRNKKSLTM--------SRDIKANNQDKTANRSIIPRSHYQKQTQEQFTSPPVRSVPASAPQ 621
Cdd:pfam15324  481 QDELARKDYEqKRFDQKNRRTAKAQAAkktsvrrqSKDIKANAQSKTPNKSVIPRKHFQKQAEEHFRKPPVRSMPASSLQ 560
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  622 ReknvrntpasapqreKNGLLKSTTTLQDEDYMFQIYGKPLYQGHRSTLKKGPYLRFSSPSPKAKPQRPRVIERVKGTKV 701
Cdd:pfam15324  561 K---------------KEGPLKSTTSLQDEDYLLQVYGKAVYQGHRSTLKKGPYLRFNSPSPKSKPQRPKVIESVKGTKV 625
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  702 KSARTQTDFHATPLTKTDSKAQHPITtLPHAHQQCVLSPSREMPTVSGTLDGHLIPMAILLGQTQSNSDSIPPAGVLVSK 781
Cdd:pfam15324  626 KSARTQTDLHATKPVKTDSKMQHSVT-APHQEQQYLFSPSREMPSQSGTLEGHLIPMAIPLGQTQSDSDSPPPAGVIVSK 704
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  782 PHPVTVTTSIPPSSRKVKAGVKKPNVAVVEMKSEKKDPPQLSVQILPSVDID--SISYSSTGGSSPSPSPKEASPPPLHT 859
Cdd:pfam15324  705 PHPVTVTTSIPPSSRKPEPGVKKPNIALLEMKSEKKDPPQLTVQVLPSVDIDsvSCSSRDSSPSPVLPSPSEASPPLIQT 784
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  860 WIQTPEFMKVDEEELPVPGTNFDEVIDVIQEEEKRDEIPECSAPMLEFNRSVKVVPTKYSGPSFPPVVSALRPTTDILDK 939
Cdd:pfam15324  785 WIQTPELMKEDEEEVKFPGTNFDEVIDVIQDEEKEDEIPEFSEPPLEFNRSVKPPSTKYNGPPFPPVVSQPQPTTDILDK 864
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842  940 VIERKETLENNLIQWVEQEIMSRIISGLFPLQQQARLDASVSVSEASEPSASDIVPGTSSGAFQLMVDAGVPVNSDMISH 1019
Cdd:pfam15324  865 VIEQRETLENRLVDWVEQEIMARIISGMFPQQAQADPDASVSESEPSEPSTSDIVEAAGGGGLQLFVDAGVPVDSEMIRH 944
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1020 FVNEALAETIAVMLADREAKKQGPAATRVSGDLSRNETNVSArvypPVATPQPTPPCSP-APLKEHVFVKTPDSSPCESD 1098
Cdd:pfam15324  945 FVNEALAETIAIMLGDREAQREPPVAASVPGDLPTKETLLPT----PVPTPQPTPPCSPpSPLKEPSPVKTPDSSPCVSE 1020
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1099 QDVaSSVKEIPVEKGSD-LPVATLVSTPTRTPVTTPPPAAALTPTLSEISIDKLKFSSPELPKPWDSGDLPLDEENPNSL 1177
Cdd:pfam15324 1021 HDF-FPVKEIPPEKGADtGPAVSLVITPTVTPIATPPPAATPTPPLSENSIDKLKSPSPELPKPWEDSDLPLEEENPNSE 1099
                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1178 QERLHPRAVVMSVAIDEEPESVASSAQpvPPEPAPLAPHLEDTKAPSLQQILSSGSSTPENTLS-TVTETETLDRHISEG 1256
Cdd:pfam15324 1100 QEELHPRAVVMSVARDEEPESVVLPAS--PPEPKPLAPPPLGAAPPSPPQSPSSSSSTLESSSSlTVTETETADRPISEG 1177
                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958785842 1257 EILLSCGQNLATKR--NGDLFLMNINDSLSTTLQDALDMEDDPPSEGQVIRRPHKKLHENAIISLLTKQEQELLVSQQA- 1333
Cdd:pfam15324 1178 EILFSYGQMLAVRAleEGGLFLPNLNDSLSSSLHDAQEMDYDPPSEGQVIRRPHKKAHHDPILSLLAKMNQGPLSSQQAv 1257
                         1290      1300
                   ....*....|....*....|....*..
gi 1958785842 1334 ---EDLDNSVGELSEGQRLVLKAAEDI 1357
Cdd:pfam15324 1258 yhsEDLENSVGELSEGQRPRLTAAAEN 1284
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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