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Conserved domains on  [gi|2024359622|ref|XP_040504347|]
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CAP-Gly domain-containing linker protein 1 isoform X10 [Gallus gallus]

Protein Classification

CAP-Gly domain-containing linker protein; CAP-Gly domain-containing protein( domain architecture ID 13652022)

CAP-Gly domain-containing linker protein similar to mammalian CLIP-170 and CLIP-115, which are homodimers and act as general promoters of microtubule growth| CAP (cytoskeleton-associated protein)-Gly domain-containing protein similar to Schizosaccharomyces pombe Tip elongation protein 1 that has a role in stabilizing and targeting the growing tips of the microtubules along the long axis of the cell, directing them to the ends of the cell

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.24e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.24e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 660-1484 1.14e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 1.14e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 720
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  721 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 789
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 869
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  870 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 943
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  944 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1016
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1080
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1081 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1144
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1145 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1224
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1225 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1304
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1305 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1378
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1379 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1455
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359622 1456 KKSLENAFSDMKREQELDFSAKRLLVQEN 1484
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1310-2026 2.66e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.66e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1381
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1382 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1461
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1462 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1541
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1542 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1621
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1622 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1701
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1702 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1764
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1765 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1810
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1811 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1890
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1891 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1970
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1971 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2026
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-973 3.96e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  343 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 422
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 502
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  503 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 582
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  583 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 662
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  663 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 735
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  736 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 811
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  812 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 891
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  892 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 961
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024359622  962 DQLTDMKKQMET 973
Cdd:COG1196    802 EQREDLEEARET 813
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2150-2166 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359622 2150 RPYCDTCEMFGHWTADC 2166
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2110-2127 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359622 2110 RLFCDICGCFDlHDTEDC 2127
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.24e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.24e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.61e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.61e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.88e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.88e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 660-1484 1.14e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 1.14e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 720
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  721 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 789
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 869
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  870 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 943
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  944 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1016
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1080
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1081 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1144
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1145 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1224
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1225 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1304
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1305 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1378
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1379 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1455
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359622 1456 KKSLENAFSDMKREQELDFSAKRLLVQEN 1484
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1310-2026 2.66e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.66e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1381
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1382 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1461
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1462 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1541
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1542 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1621
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1622 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1701
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1702 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1764
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1765 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1810
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1811 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1890
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1891 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1970
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1971 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2026
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 806-1656 8.41e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 87.33  E-value: 8.41e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  806 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 884
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  885 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 962
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  963 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1042
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1043 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1122
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1123 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1202
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1203 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1275
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1276 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1355
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1356 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1435
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1436 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1514
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1515 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1594
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622 1595 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1656
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1022-1666 1.17e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1022 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1098
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1099 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1178
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1179 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1258
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1259 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1338
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1339 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1418
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1419 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1496
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1497 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1576
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1577 NMKENLTVEKKARILDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1656
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024359622 1657 EQLASKIEQL 1666
Cdd:COG1196    770 ERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 520-1320 7.04e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 7.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  520 KEHQREMSSLKEKFESSEEALRKEiktlsasnerMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKV 599
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTE----------TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR 1153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  600 SFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKakllevTEEKEQTLENLKAKLESVEDQ 679
Cdd:PTZ00121  1154 VEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAAR------KAEEERKAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  680 HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 759
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  760 IQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN- 838
Cdd:PTZ00121  1308 KKKAEEAK-----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADa 1382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  839 -QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKS-SGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:PTZ00121  1383 aKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE----EKKKAdEAKKKAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 IQLELTKANEKavqlqKNVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 995
Cdd:PTZ00121  1459 AEEAKKKAEEA-----KKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  996 HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEElKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNT 1075
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1076 LKLEKESLLSQHL----EMESKILLVQQDREELWTKNEELN--SENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSE 1149
Cdd:PTZ00121  1613 KKAEEAKIKAEELkkaeEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1150 IETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQS 1228
Cdd:PTZ00121  1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1229 syddlARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQ 1308
Cdd:PTZ00121  1773 -----IRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD 1847

                          810
                   ....*....|..
gi 2024359622 1309 ALKLRKDEMQTE 1320
Cdd:PTZ00121  1848 AFEKHKFNKNNE 1859
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-973 3.96e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  343 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 422
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 502
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  503 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 582
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  583 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 662
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  663 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 735
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  736 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 811
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  812 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 891
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  892 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 961
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024359622  962 DQLTDMKKQMET 973
Cdd:COG1196    802 EQREDLEEARET 813
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 6.01e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 70.87  E-value: 6.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 348-961 9.10e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.92  E-value: 9.10e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  348 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 416
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  417 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENVatvseKSRIMELERDLALRVKEVAELRgrlESSKHID 496
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNL-----DDQLQKLLADLHKREKELSLEK---EQNKRLW 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  497 DVDTSLSLlqEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENeSLKTKLDHANKENSDVI 576
Cdd:pfam15921  405 DRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMLRKVV 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKlESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyenemsNLKLKQenekSQHLKEiealkakll 656
Cdd:pfam15921  482 EELTAK-KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---------DLKLQE----LQHLKN--------- 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  657 evteeKEQTLENLKAKLESVedqhlvemedtlnKLQEAEiKVKELDVLQAKCNEQTKLIGsltQQIRASEEKLLDLAALQ 736
Cdd:pfam15921  539 -----EGDHLRNVQTECEAL-------------KLQMAE-KDKVIEILRQQIENMTQLVG---QHGRTAGAMQVEKAQLE 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  737 KANSEGKLEIQKLS-------EQLQAAEKQIQNLETEKV----GGSSKVSNLTKELQGKEQKLLDLEKNLSAVNqvkdSL 805
Cdd:pfam15921  597 KEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVklvnAGSERLRAVKDIKQERDQLLNEVKTSRNELN----SL 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  806 EKELQLLKEKFTSAVDGAE-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTV 860
Cdd:pfam15921  673 SEDYEVLKRNFRNKSEEMEtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQF 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  861 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 940
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650       660
                   ....*....|....*....|.
gi 2024359622  941 KAEQSQQETLKTHQEELKKMQ 961
Cdd:pfam15921  829 RQEQESVRLKLQHTLDVKELQ 849
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
332-891 7.19e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 7.19e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  332 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrDGHDRHVLEMEAKMDQLRAMVEAA 411
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  412 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENvaTVSEKSRIMELERDLALRVKEVAELRGRLES 491
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  492 SKhiddvdtslsllQEISSLQEKMaaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 571
Cdd:PRK03918   336 KE------------ERLEELKKKL----KELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  572 NSDvIELWKSKLESAIASHQQAMEELKVSFNKgvgaqtAEFAELKTQMEKVKLDYENEmsnlklkqENEKSQHLKEIEAL 651
Cdd:PRK03918   400 KEE-IEEEISKITARIGELKKEIKELKKAIEE------LKKAKGKCPVCGRELTEEHR--------KELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  652 KAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IGSLTQQIRA 724
Cdd:PRK03918   465 EKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  725 SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 804
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  805 LEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL 882
Cdd:PRK03918   621 LKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699


                   ....*....
gi 2024359622  883 ENDIAEIMK 891
Cdd:PRK03918   700 KEELEEREK 708
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1730-2029 8.04e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 8.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1730 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1809
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1810 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1889
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1890 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1969
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1970 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2029
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1310-1988 9.36e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 9.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1386
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1387 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1461
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1462 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1539
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1540 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1600
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1601 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1671
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1672 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1748
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1749 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1824
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1825 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1892
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1893 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1953
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359622 1954 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1988
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1611-2025 4.05e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 4.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1611 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1690
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1691 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1770
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1771 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1850
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1851 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1925
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1926 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2005
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359622 2006 LESDKLKLEEKVKNLEQKLK 2025
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.38e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.38e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2150-2166 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359622 2150 RPYCDTCEMFGHWTADC 2166
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 335-694 8.01e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 8.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  335 ARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDR----------HVLEMEAKMDQL 404
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEElsrqisalrkDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  405 RAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDpenvATVSEKSRIMELERDLALRVKEVAE 484
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE----ELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  485 LRGRLESS-KHIDDVDTSLS-LLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLK 562
Cdd:TIGR02168  822 LRERLESLeRRIAATERRLEdLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNERASLEEALALLRSELEELS 900

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  563 TKLDHANKENSDVIELwKSKLESAIASHQQAMEELKVsfnkgvgaqtaEFAELKTQ-MEKVKLDYEN--EMSNLKLKQEN 639
Cdd:TIGR02168  901 EELRELESKRSELRRE-LEELREKLAQLELRLEGLEV-----------RIDNLQERlSEEYSLTLEEaeALENKIEDDEE 968

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  640 EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEA 694
Cdd:TIGR02168  969 EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQK-EDLTEAKETLEEA 1022
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2110-2127 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359622 2110 RLFCDICGCFDlHDTEDC 2127
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 717-996 1.16e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  717 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 796
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  797 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 871
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  872 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 949
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359622  950 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 996
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 217-281 8.09e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 124.82  E-value: 8.09e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  217 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLFAPVHKV 281
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 61-125 5.24e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.73  E-value: 5.24e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622   61 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRPSKL 125
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 217-282 2.61e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.52  E-value: 2.61e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622   217 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPRYGLFAPVHKVT 282
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 61-126 2.88e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 2.88e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622    61 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLRGIFTRPSKLS 126
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 660-1484 1.14e-24

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 113.23  E-value: 1.14e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQ-------------------EAEIKVKELDVLQAKCNEQTKLIGSLTQ 720
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDI-LNELERQLKSLErqaekaerykelkaelrelELALLVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  721 QIRASEEKL----LDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK-------ELQGKEQKLL 789
Cdd:TIGR02168  254 ELEELTAELqeleEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERqleeleaQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 869
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  870 EREQQLTE-----AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE- 943
Cdd:TIGR02168  414 DRRERLQQeieelLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDs 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  944 -QSQQETLKTHQEELKkmqdQLTDMKKQMETSQNQYKDL---QAKYEKETsemitkhDADIKGFKQNLL--DAEEALKA- 1016
Cdd:TIGR02168  494 lERLQENLEGFSEGVK----ALLKNQSGLSGILGVLSELisvDEGYEAAI-------EAALGGRLQAVVveNLNAAKKAi 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 -AQKKND---------------ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEK 1080
Cdd:TIGR02168  563 aFLKQNElgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1081 E----------------SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1144
Cdd:TIGR02168  643 PgyrivtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1145 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQ 1224
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE----------LEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1225 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTA 1304
Cdd:TIGR02168  793 QLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1305 NENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL------LQEALFASEQRL 1378
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLevridnLQERLSEEYSLT 952

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1379 LAEREELVNENKAVTEKLTKATADAvlaetafTEKINEL---NLEKESvfskslQFEKHNEallrEKDELERKYSELLDE 1455
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRL-------ENKIKELgpvNLAAIE------EYEELKE----RYDFLTAQKEDLTEA 1015

                          890       900
                   ....*....|....*....|....*....
gi 2024359622 1456 KKSLENAFSDMKREQELDFSAKRLLVQEN 1484
Cdd:TIGR02168 1016 KETLEEAIEEIDREARERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 785-1666 3.00e-22

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 105.14  E-value: 3.00e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  785 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRamqetinklnqkeeqFALMSSELEQLKSNLTVMEtk 864
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQ-------AEKAER---------------YKELKAELRELELALLVLR-- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  865 LKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKaeq 944
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEEL--------------TAELQELEEKLEELRLEVSELEEEIEELQKELYALANE--- 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  945 sqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDEL 1024
Cdd:TIGR02168  297 --ISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL----EEKLEELKEELESLEAELEELEAELEEL 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1025 ETQAEELKKQAEQAKS----LSSVLASARKEIELMSDKMRDLISEKETLAQERNTlkLEKESLLSQHLEMESKILLVQQD 1100
Cdd:TIGR02168  371 ESRLEELEEQLETLRSkvaqLELQIASLNNEIERLEARLERLEDRRERLQQEIEE--LLKKLEEAELKELQAELEELEEE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1101 REELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS---KLLSEIETAQADLLKITQENDALRSSESTLLQQ 1177
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDsleRLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1178 LKELQANKDAVDVACQKHIkereelehyQKLLEENDRVIKD-----KDDVIQRL------QSSYDDLARNQRELLQEVsi 1246
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRL---------QAVVVENLNAAKKaiaflKQNELGRVtflpldSIKGTEIQGNDREILKNI-- 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1247 ltaerDSAQEKDLDLKSTHIALKNEIDCLLQTNR---SLQSEKEMLLKSR-EELCVSLANT-------------ANENQA 1309
Cdd:TIGR02168  598 -----EGFLGVAKDLVKFDPKLRKALSYLLGGVLvvdDLDNALELAKKLRpGYRIVTLDGDlvrpggvitggsaKTNSSI 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKdemqtELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAEREELVNEN 1389
Cdd:TIGR02168  673 LERRR-----EIEELEEKIEELEEKIAELEKALAELRKELEELE--------EELEQLRKELEELSRQISALRKDLARLE 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1390 KAVtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1469
Cdd:TIGR02168  740 AEV-EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1470 QELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1549
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1550 CSSDIEILNRERTELQDKCQKLTGEVENMKENLTV------EKKARILDKESFLLERM-ELQNNIGF----LEKEVEEMR 1618
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGlevridNLQERLSEEYSLTLEEAeALENKIEDdeeeARRRLKRLE 978

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359622 1619 EKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQL 1666
Cdd:TIGR02168  979 NKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1310-2026 2.66e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 2.66e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRLLA--------E 1381
Cdd:TIGR02168  170 YKERRKETERKLERTRENLDRLEDILNELERQLKSLE---------RQAEKAERYKELKAELRELELALLVlrleelreE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1382 REELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLEN 1461
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1462 AFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQ 1541
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1542 VLSSSFNTCSSDIEILNRERTELQdkcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKN 1621
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1622 KEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVT 1701
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1702 EKEK----MELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFS-------CRLLV------ 1764
Cdd:TIGR02168  554 NLNAakkaIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllGGVLVvddldn 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1765 -------------------------------SEGKHELLLE---EMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQT 1810
Cdd:TIGR02168  634 alelakklrpgyrivtldgdlvrpggvitggSAKTNSSILErrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1811 MEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQ 1890
Cdd:TIGR02168  714 LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1891 KSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLpsNTLREStlKKEIDEERASLQKSISDTSA 1970
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEA---ANLRERLESLERRIAATERRL--EDLEEQ--IEELSEDIESLAAEIEELEE 866

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1971 LITQKDEELEKLRNEITVLRGENASAK----TLQSVVKTLESDKLKLEEKVKNLEQKLKA 2026
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRseleELSEELRELESKRSELRRELEELREKLAQ 926
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 396-1236 3.21e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 3.21e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  396 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLE-RKRQISEDPENVATVSEK--SRIMELE 472
Cdd:TIGR02168  250 EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEqQKQILRERLANLERQLEEleAQLEELE 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  473 RDLALRVKEVAELRGRLEsskhiddvdtslSLLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNE 552
Cdd:TIGR02168  330 SKLDELAEELAELEEKLE------------ELKEELESLEAELEELEAE-LEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  553 RMGKENESLKTKLDHANKEnsdvielwKSKLESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSN 632
Cdd:TIGR02168  397 SLNNEIERLEARLERLEDR--------RERLQQEIEELLKKLEEAELK------ELQAELEELEEELEELQEELERLEEA 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  633 LKLKQEneksqhlkEIEALKAKLLEvTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT 712
Cdd:TIGR02168  463 LEELRE--------ELEEAEQALDA-AERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  713 K--------LIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSeqlQAAEKQIQNLETEKVGGSSKVSNLTKELQGK 784
Cdd:TIGR02168  534 GyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD---SIKGTEIQGNDREILKNIEGFLGVAKDLVKF 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  785 EQKLLDLEKNLSAVNQVKDSLEKELQLLKEK------FT----------SAVDGAENAQRAMQETINKLNQKEEQFALMS 848
Cdd:TIGR02168  611 DPKLRKALSYLLGGVLVVDDLDNALELAKKLrpgyriVTldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  849 SELEQLKSNLTVMETKLkereereQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKA 928
Cdd:TIGR02168  691 EKIAELEKALAELRKEL-------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  929 VQLQKNVEQTaqkaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfKQNLL 1008
Cdd:TIGR02168  764 EELEERLEEA--------EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL---------------NEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1009 DAEEALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLL 1084
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSedieSLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1085 SQHLEMESKILLVQQDREELWTKNEELNsENKKILKQKEA--AEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1162
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLE-LRLEGLEVRIDnlQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1163 ENDALRSSESTLLQQLKELQANKDAVDvacqkhiKEREELEHYQKLLEEndrVIKDKDDVI-QRLQSSYDDLARN 1236
Cdd:TIGR02168  980 KIKELGPVNLAAIEEYEELKERYDFLT-------AQKEDLTEAKETLEE---AIEEIDREArERFKDTFDQVNEN 1044
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 348-1039 6.42e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.89  E-value: 6.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  348 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHdrhvLEMEAKMDQLRAMVEAADREKVELLNQLEEEKR 427
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  428 KVEDLQFRVEEESITKGDLERKRQisEDPENVATVSEKsrIMELERDLALRVKEVAELRGRLESSKhiddvdtslSLLQE 507
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLD--ELAEELAELEEK--LEELKEELESLEAELEELEAELEELE---------SRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  508 ISSLQEKMAAAGKEHQREMSSLKEKFESseeaLRKEIKTLSASNERMGKENESLKTKLDHANKE----NSDVIELWKSKL 583
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEIER----LEARLERLEDRRERLQQEIEELLKKLEEAELKelqaELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  584 ESAIASHQQAMEELKVSFNKGVGAQTA---EFAELKTQMEKVKLDYENEMSNLKLKQENEKSQH-LKEIEALKAKLLEVT 659
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEGVKALLKNQSgLSGILGVLSELISVD 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLEnlkAKLESVEDQHLVEMEDTLNKLQEA--EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 737
Cdd:TIGR02168  533 EGYEAAIE---AALGGRLQAVVVENLNAAKKAIAFlkQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  738 ANSEGKLEIQKLSEQL-------QAAEKQIQNLETEK---------------VGGSSKVSNLT----KELQGKEQKLLDL 791
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVlvvddldNALELAKKLRPGYRivtldgdlvrpggviTGGSAKTNSSIlerrREIEELEEKIEEL 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  792 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER 871
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  872 EQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLK 951
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ-IE 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  952 THQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsemitKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEEL 1031
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERA--------SLEEALALLRSELEELSEELRELESKRSELRRELEEL 920


                   ....*...
gi 2024359622 1032 KKQAEQAK 1039
Cdd:TIGR02168  921 REKLAQLE 928
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 863-1740 1.01e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 1.01e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  863 TKLKER-EEREQQLTEAKVKLE--NDIAEIMKSSGDS-SAQLMKMNDELRLKErQLEQIQLELTKAneKAVQLQKNVEQT 938
Cdd:TIGR02168  168 SKYKERrKETERKLERTRENLDrlEDILNELERQLKSlERQAEKAERYKELKA-ELRELELALLVL--RLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  939 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSE------MITKHDADIKGFKQNLLDAEE 1012
Cdd:TIGR02168  245 QEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEisrleqQKQILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1013 ALKAAQKKNDELETQAEELKKQAEQAK----SLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1088
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEEKLEELKeeleSLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1089 EMESKILLVQQDREELWTKNEELNsenkkilkqKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1168
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELL---------KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1169 SSESTLLQQLKELQANKDAVDVACQKHIKERE---ELEHYQKLLEENDRVIKDKDDVIQR--------LQSSYDDLA-RN 1236
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEgvkALLKNQSGLSGILGVLSELISVDEGyeaaieaaLGGRLQAVVvEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1237 QRELLQEVSILTAERDS-------AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQA 1309
Cdd:TIGR02168  555 LNAAKKAIAFLKQNELGrvtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKdEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLAEREELvnen 1389
Cdd:TIGR02168  635 LELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEE--LEEKIEELEEKIAELEKALAELRKEL---- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1390 kavtEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE 1469
Cdd:TIGR02168  708 ----EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1470 QEldfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNT 1549
Cdd:TIGR02168  784 IE--------------ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1550 CSSDIEILNRERTELQDKCQKLTGEVENMKEnltvekkarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE 1629
Cdd:TIGR02168  850 LSEDIESLAAEIEELEELIEELESELEALLN-----------ERASLEEALALLRSELEELSEELRELESKRSELRRELE 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1630 LLVQEKEKSETKLEEvikekmilyketeqLASKIEQLKSDFTSLsvskaeledvhscVSVMLDELQHKYEVTEKEKMELV 1709
Cdd:TIGR02168  919 ELREKLAQLELRLEG--------------LEVRIDNLQERLSEE-------------YSLTLEEAEALENKIEDDEEEAR 971

                          890       900       910
                   ....*....|....*....|....*....|.
gi 2024359622 1710 QENESLHAEWKSLVIINEEILKEKEKLSKEY 1740
Cdd:TIGR02168  972 RRLKRLENKIKELGPVNLAAIEEYEELKERY 1002
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 906-1800 1.22e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 90.13  E-value: 1.22e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  906 ELRLKERQLEQIQLELTKANEKAVQLQKNVEqtaqKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 985
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRRERE----KAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  986 EKETSEmitkhdadikgfkqnlldAEEALKAAQKKNDELETQAEELKKQAE-QAKSLSSVLASARKEIELMSDKMRDLIS 1064
Cdd:TIGR02169  254 EKLTEE------------------ISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1065 EKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS 1144
Cdd:TIGR02169  316 ELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1145 KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQ 1224
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQE---WKLEQLAADLSKYEQELY 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1225 RLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSRE-ELCVSLANT 1303
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEvAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1304 ANENQA--------LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASE 1375
Cdd:TIGR02169  553 VVEDDAvakeaielLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAA 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1376 QRLLAERE------ELVNENKAVTEKLTKATADAVLAeTAFTEKINELNLEKESVfskslqfEKHNEALLREKDELERKY 1449
Cdd:TIGR02169  633 RRLMGKYRmvtlegELFEKSGAMTGGSRAPRGGILFS-RSEPAELQRLRERLEGL-------KRELSSLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1450 SELLDEKKSLENAFSDMKREQELdfsakrlLVQENTTLKYSIEALEEELKKKNlenQELIACRSDLSDLLKEAQDARRTL 1529
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQ-------LEQEEEKLKERLEELEEDLSSLE---QEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1530 ENELAAVSHAKQVLSSSFntcssdIEILNRERTELQDKCQKLTGEVENMKenltvekkaRILDKESFLLErmelqnnigF 1609
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSR------IPEIQAELSKLEEEVSRIEARLREIE---------QKLNRLTLEKE---------Y 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1610 LEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSV 1689
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEA 910

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1690 MLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEIL------KEKEKLSKEYYKLhEKVVALLEQTDADFSCRLL 1763
Cdd:TIGR02169  911 QIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqAELQRVEEEIRAL-EPVNMLAIQEYEEVLKRLD 989

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 2024359622 1764 VSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEA 1800
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1877 3.07e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 3.07e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1023 ELETQAEELKKQAEQA---KSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKI 1094
Cdd:TIGR02168  197 ELERQLKSLERQAEKAeryKELKAELRELELALLVLRleelrEELEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1095 LLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQestekvalisekskLLSEIETAQADLLKITQENDALRSSESTL 1174
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLAN--------------LERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1175 LQQLKELQANKDAvdvacqkhikEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLaRNQRELLQevsiltaerdsa 1254
Cdd:TIGR02168  343 EEKLEELKEELES----------LEAELEELEAELEELESRLEELEEQLETLRSKVAQL-ELQIASLN------------ 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1255 qekdldlksthialkNEIDCLLQTNRSLQSEKEMLLKSREELcvslantanENQALKLRKDEMQTELETEREKLEKMTKD 1334
Cdd:TIGR02168  400 ---------------NEIERLEARLERLEDRRERLQQEIEEL---------LKKLEEAELKELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1335 NMDLKASLSSLSNFLEEMKSSREASNSEKIHLlqEALFASEQRLLAEREELVNENKAVT-EKLTKATADAVLAETAFTEk 1413
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQENLEGFSEGVKALLkNQSGLSGILGVLSELISVD- 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1414 iNELNLEKESVFSKSLQfekhneALLREKDELERKYSELLDEKKSLENAFS--DMKREQELDFSAKRLLVQENTTLKYSI 1491
Cdd:TIGR02168  533 -EGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQNELGRVTFLplDSIKGTEIQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1492 EALEEELKKKNLENQELIACRsdLSDLLKEAQDARRTLENELAAVSHAKQVLSSSF-------NTCSSD------IEILN 1558
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVL--VVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSIlerrreIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1559 RERTELQDKCQKLTGEVENMKENLT-VEKKARILDKESFLLERM--ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK 1635
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEeLEEELEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1636 EKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESL 1715
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1716 HAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvSEGKHELLLEEMSNLALKLREIERlqaqtfm 1795
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS--------LEEALALLRSELEELSEELRELES------- 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1796 QKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE 1875
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL------SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982


                   ..
gi 2024359622 1876 EL 1877
Cdd:TIGR02168  983 EL 984
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 806-1656 8.41e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 87.33  E-value: 8.41e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  806 EKELQLLKEKFTSAVDGAENAQRAMQETINKLN-QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 884
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKlKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  885 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQD 962
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSEllKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  963 QLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLS 1042
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1043 SVLASARKEIELMSDKMRDLISEKETLaQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1122
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEE-EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1123 EAAEAKSRQESTEKvaliSEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREEL 1202
Cdd:pfam02463  488 LLLSRQKLEERSQK----ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1203 EHYQKLLEENDR-------VIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCL 1275
Cdd:pfam02463  564 QKLVRALTELPLgarklrlLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1276 LQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSS 1355
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1356 REASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHN 1435
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1436 EALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQ-ELIACRSD 1514
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLkEEELEEQK 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1515 LSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1594
Cdd:pfam02463  884 LKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622 1595 SFLLERMELQNNigfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKET 1656
Cdd:pfam02463  964 RLLLAKEELGKV---NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEF 1022
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1022-1666 1.17e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.17e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1022 DELETQAEELKKQAEQA---KSLSSVLAsaRKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQ 1098
Cdd:COG1196    196 GELERQLEPLERQAEKAeryRELKEELK--ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1099 QDREELwtkNEELNsenkkilkqkeaaeaksrqestekvALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1178
Cdd:COG1196    274 LELEEL---ELELE-------------------------EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1179 KELQankdavdvacQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKD 1258
Cdd:COG1196    326 AELE----------EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1259 LDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDL 1338
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1339 KASLSSLSNFLEEMKSSREASNSEkihLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELN 1418
Cdd:COG1196    476 EAALAELLEELAEAAARLLLLLEA---EADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1419 LEKESVFSKSLQFEKHNEA--LLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEE 1496
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1497 ELKKKnlenqeliacrsdlsdLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVE 1576
Cdd:COG1196    633 EAALR----------------RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1577 NMKENLTVEKKARILDKEsfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEkmiLYKET 1656
Cdd:COG1196    697 EALLAEEEEERELAEAEE----ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE---LEREL 769

                          650
                   ....*....|
gi 2024359622 1657 EQLASKIEQL 1666
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 406-1256 2.13e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.89  E-value: 2.13e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  406 AMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAEL 485
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  486 RGRLES-SKHIDDVDtslsllQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTK 564
Cdd:TIGR02169  243 ERQLASlEEELEKLT------EEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERE 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  565 LDHANKENSDVIELwKSKLESAIASHQQAMEELKVSfnkgVGAQTAEFAELKTQMEKV-----KLDYENEMSNLKLKQEN 639
Cdd:TIGR02169  317 LEDAEERLAKLEAE-IDKLLAEIEELEREIEEERKR----RDKLTEEYAELKEELEDLraeleEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  640 EKSQHLK----EIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemedtlNKLQEaeikvkELDVLQAKCNEQTKLI 715
Cdd:TIGR02169  392 EKLEKLKreinELKRELDRLQEELQRLSEELADLNAAIAGIEAKI--------NELEE------EKEDKALEIKKQEWKL 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  716 GSLTQQIRASEEKLLDLAALQKANSEgklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQG-----------K 784
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEEYDRVEK---ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlgsvG 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  785 EQKLLDLE----KNLSAVNQVKDSLEKE-LQLLKEKftsavdgaeNAQRAMQETINKLNQKEEQ-----------FALMS 848
Cdd:TIGR02169  535 ERYATAIEvaagNRLNNVVVEDDAVAKEaIELLKRR---------KAGRATFLPLNKMRDERRDlsilsedgvigFAVDL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  849 SELEQLKSNLTVM---ETKLKEREE--REQQLTEAKVKLENDIAE--------IMKSSGDSS------AQLMKMNDELRL 909
Cdd:TIGR02169  606 VEFDPKYEPAFKYvfgDTLVVEDIEaaRRLMGKYRMVTLEGELFEksgamtggSRAPRGGILfsrsepAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  910 KERQLEQIQLELTKAnekavqlqknveqtaqkaeqsqqetlkthQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEt 989
Cdd:TIGR02169  686 LKRELSSLQSELRRI-----------------------------ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL- 735

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  990 SEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE--QAKSLSSVLASARKEIELMSDKMRDLISEKE 1067
Cdd:TIGR02169  736 KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSKLEEEVSRIEARLR 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1068 TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLL 1147
Cdd:TIGR02169  816 EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELE 895

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1148 SEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRV---IKDKDDVIQ 1224
Cdd:TIGR02169  896 AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVeeeIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|..
gi 2024359622 1225 RLQSSYDDLARNQRELLQEVSILTAERDSAQE 1256
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 993-1886 2.94e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.50  E-value: 2.94e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  993 ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAkslssvlasarkeielmsDKMRDLISEKEtlaqe 1072
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA------------------ERYQALLKEKR----- 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1073 rntlKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEkskllsEIET 1152
Cdd:TIGR02169  222 ----EYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLR 291

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1153 AQADLLKITQENDALRSSESTLLQQLKELQAnkdavdvacqKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD 1232
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEE----------RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1233 LARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKL 1312
Cdd:TIGR02169  362 LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1313 RKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMkssreasnSEKIHLLQEALFASEQRLLAEREElVNENKAV 1392
Cdd:TIGR02169  442 EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV--------EKELSKLQRELAEAEAQARASEER-VRGGRAV 512

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1393 TE--------------KLTKATADAVLA-ETAFTEKINELNLEKESVFSKSLQFEKHNEA-----LLREKDELERKYSEL 1452
Cdd:TIGR02169  513 EEvlkasiqgvhgtvaQLGSVGERYATAiEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAgratfLPLNKMRDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1453 LDEKKSLENAFSDMKREQEldFSAKRLLVQENTTLKYSIEAleeelKKKNLENQELIACRSDL----------SDLLKEA 1522
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPK--YEPAFKYVFGDTLVVEDIEA-----ARRLMGKYRMVTLEGELfeksgamtggSRAPRGG 665

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1523 QDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTvekkaRILDKESFLLERME 1602
Cdd:TIGR02169  666 ILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIE-----QLEQEEEKLKERLE 740

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1603 -LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVikEKMILYKETEQLASKIEQLKSDFTSLSVSKAELE 1681
Cdd:TIGR02169  741 eLEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1682 dvhscvsVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALleqtdadfscr 1761
Cdd:TIGR02169  819 -------QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL----------- 880

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1762 llvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIH------QEKIETLASLENS 1835
Cdd:TIGR02169  881 ----ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdpkgedEEIPEEELSLEDV 956

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1836 RQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKL 1886
Cdd:TIGR02169  957 QAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILE 1007
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 685-1334 4.97e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 84.60  E-value: 4.97e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  685 EDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRA--------SEEKLLDLAALqkansegKLEIQKLSEQLQAA 756
Cdd:COG1196    175 EEAERKLEATE---ENLERLEDILGELERQLEPLERQAEKaeryrelkEELKELEAELL-------LLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  757 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 836
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  837 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:COG1196    325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDmKKQMETSQNQYKDLQAKYEKETSEMITKH 996
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL-EEEEEALLELLAELLEEAALLEAALAELL 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  997 DADIKgfkqnlLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARK---------EIELMSDKMRDLISEKE 1067
Cdd:COG1196    484 EELAE------AAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGveaayeaalEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1068 TLAQERNTLKLEKE-----------------SLLSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSR 1130
Cdd:COG1196    558 VAAAAIEYLKAAKAgratflpldkiraraalAAALARGAIGAAVDLVASDLREA----DARYYVLGDTLLGRTLVAARLE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1131 QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLE 1210
Cdd:COG1196    634 AALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1211 ENDRviKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthiALKNEIdcllqtnRSLQSEKEML- 1289
Cdd:COG1196    714 EERL--EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLE----ELEREL-------ERLEREIEALg 780

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1290 ---LKSREELcvslantanenQALKLRKDEMQTE---LETEREKLEKMTKD 1334
Cdd:COG1196    781 pvnLLAIEEY-----------EELEERYDFLSEQredLEEARETLEEAIEE 820
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 344-1010 5.90e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 5.90e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  344 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDrhvlEMEAKMDQLRAMVEAADREKVELLNQLE 423
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  424 EEKRKVEDLQFRVEEESITKGDLERKRQI-SEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLEsskhiDDVDTSL 502
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE-----RLEEALE 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  503 SLLQEISSLQEKMAAAGKEHQREMSSLK--EKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKensdvielWK 580
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQLQARLDslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEG--------YE 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  581 SKLESAIASHQQAME-------ELKVSFNKGVGAQTAEFAELKTqmekVKLDYENEMSNLKLKQENEKSQHLKEIEALKA 653
Cdd:TIGR02168  537 AAIEAALGGRLQAVVvenlnaaKKAIAFLKQNELGRVTFLPLDS----IKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  654 KL----------LEVTEEKEQTLENLKAKLES----VEDQHLV----------------------EMEDTLNKLQEAEIK 697
Cdd:TIGR02168  613 KLrkalsyllggVLVVDDLDNALELAKKLRPGyrivTLDGDLVrpggvitggsaktnssilerrrEIEELEEKIEELEEK 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  698 VKELDV-LQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSN 776
Cdd:TIGR02168  693 IAELEKaLAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  777 LTKELQGKEQKLLDLEK-------NLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSS 849
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAqieqlkeELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE 852

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  850 ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 929
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  930 QLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL---------QAKYEKETSEMITKHDADI 1000
Cdd:TIGR02168  933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaieEYEELKERYDFLTAQKEDL 1012

                          730
                   ....*....|
gi 2024359622 1001 KGFKQNLLDA 1010
Cdd:TIGR02168 1013 TEAKETLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 520-1184 9.80e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 9.80e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  520 KEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKSKLESAIASHQQAMEELKV 599
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE-ISRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  600 SfNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhLKEIEALKAKLLEVTEEKEQTLENLKAKLesveDQ 679
Cdd:TIGR02168  317 Q-LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-LEELEAELEELESRLEELEEQLETLRSKV----AQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  680 HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT-------------KLIGSLTQQIRASEEKLLDLAALQKANSEGKLEI 746
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIeellkkleeaelkELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  747 QKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkEKFTSAVDGA--- 823
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-----EGYEAAIEAAlgg 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  824 -------ENAQRAMQeTINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ----LTEAKVKLENDIAE---- 888
Cdd:TIGR02168  546 rlqavvvENLNAAKK-AIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGvakdLVKFDPKLRKALSYllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  889 --IMKSSGDSSAQLMKMNDELRL---------------------------KERQLEQIQLELTKANEKAVQLQKNVEQTA 939
Cdd:TIGR02168  625 vlVVDDLDNALELAKKLRPGYRIvtldgdlvrpggvitggsaktnssileRRREIEELEEKIEELEEKIAELEKALAELR 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  940 QKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIKGFKQNLLDAEEALKAAQK 1019
Cdd:TIGR02168  705 KELEELEEE-LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-LTELEAEIEELEERLEEAEEELAEAEA 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1020 KNDELETQAEELKkqaEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQ 1099
Cdd:TIGR02168  783 EIEELEAQIEQLK---EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1100 DREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLK 1179
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID 939


                   ....*
gi 2024359622 1180 ELQAN 1184
Cdd:TIGR02168  940 NLQER 944
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1164-1957 1.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 79.72  E-value: 1.78e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1164 NDALRSSESTLL-QQLKELQANKDAVDVACQKHIKEREELehyQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQ 1242
Cdd:TIGR02168  219 KAELRELELALLvLRLEELREELEELQEELKEAEEELEEL---TAELQELEEKLEELRLEVSELEEEIEELQKELYALAN 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1243 EVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELE 1322
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1323 TEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL---VNENKAVTEKLTKA 1399
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqaeLEELEEELEELQEE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1400 TADAVLAETAFTEKINELNLEKESVFSK--SLQFEKHN-EALLREKDELERKYSELLDEKKSLENAFS--------DMKR 1468
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERElaQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvDEGY 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1469 EQELDF----SAKRLLVQENTTLKYSIEALEEELKKK------------------NLENQELIACRSDLSDLLKEAQDAR 1526
Cdd:TIGR02168  536 EAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELGRvtflpldsikgteiqgndREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1527 RTLENELAAVshakqVLSSSFNTCSSDIEILNRERT------ELQDKCQKLTGEVENmKENLTVEKKARILDKESfllER 1600
Cdd:TIGR02168  616 KALSYLLGGV-----LVVDDLDNALELAKKLRPGYRivtldgDLVRPGGVITGGSAK-TNSSILERRREIEELEE---KI 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1601 MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAEL 1680
Cdd:TIGR02168  687 EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1681 EDvhscvsvMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvVALLEQTDADFSC 1760
Cdd:TIGR02168  767 EE-------RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER-LESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1761 RLLVSEGKHELLLEEMSNLALKLRE----IERLQAQT------FMQKFEADKRAEEVLQTMEKVTKEKDaihQEKIETLA 1830
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEEleelIEELESELeallneRASLEEALALLRSELEELSEELRELE---SKRSELRR 915

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1831 SLENSRQTNEKLQNELDMLKQNNLKNEEELTkSKELLNLENKKVEELKKEFEALKLAAAQKS--QQLAALQEENVKLAEE 1908
Cdd:TIGR02168  916 ELEELREKLAQLELRLEGLEVRIDNLQERLS-EEYSLTLEEAEALENKIEDDEEEARRRLKRleNKIKELGPVNLAAIEE 994

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359622 1909 LgrsrdevtshQKLEEERSVLNNQLLEMKKSLpsNTLRESTlkKEIDEE 1957
Cdd:TIGR02168  995 Y----------EELKERYDFLTAQKEDLTEAK--ETLEEAI--EEIDRE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 336-1083 2.24e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.24e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  336 RKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQeLALVRDghdrhVLEMEAKMDQLRAMVEA----- 410
Cdd:TIGR02169  244 RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ-LRVKEK-----IGELEAEIASLERSIAEkerel 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  411 --ADREKVELLNQLEEEKRKVEDLQFRVEEESItkgdleRKRQISEDPENVATVSEK--SRIMELERDLALRVKEVAELR 486
Cdd:TIGR02169  318 edAEERLAKLEAEIDKLLAEIEELEREIEEERK------RRDKLTEEYAELKEELEDlrAELEEVDKEFAETRDELKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  487 GRLESSKH-IDDVDTSLSLLQEissLQEKMAAAGKEHQREMSSLKEK---FESSEEALRKEIK-------TLSASNERMG 555
Cdd:TIGR02169  392 EKLEKLKReINELKRELDRLQE---ELQRLSEELADLNAAIAGIEAKineLEEEKEDKALEIKkqewkleQLAADLSKYE 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  556 KENESLKTKLDHANKENSDVielwKSKLESAIASHQQ---------AMEELKVSFNKGVGAQTAEFAELKTQMEK-VKLD 625
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKL----QRELAEAEAQARAseervrggrAVEEVLKASIQGVHGTVAQLGSVGERYATaIEVA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  626 YENEMSNLKLKQEN---EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ--HLVEMEDtlnKLQEAEIKVKE 700
Cdd:TIGR02169  545 AGNRLNNVVVEDDAvakEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFavDLVEFDP---KYEPAFKYVFG 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  701 LDVLQAKCNEQTKLIGSLTQQIRASE--EK-------LLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 771
Cdd:TIGR02169  622 DTLVVEDIEAARRLMGKYRMVTLEGElfEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  772 SKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 851
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  852 EQLKSnltvmetklKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQLELTKANEKAV 929
Cdd:TIGR02169  782 NDLEA---------RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYleKEIQELQEQRIDLKEQIKSI 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  930 Q-----LQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETsemitKHDADIKGFK 1004
Cdd:TIGR02169  853 EkeienLNGKKEELEEELEELEAA-LRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR-----KRLSELKAKL 926

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1005 QNLLDAEEALKAAQKKNDE-------LETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLK 1077
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*.
gi 2024359622 1078 LEKESL 1083
Cdd:TIGR02169 1007 ERIEEY 1012
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 591-1436 2.44e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.44e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  591 QQAMEELKVsfnkgVGAQTAEF----AELKTQMEKVKLDYENEMSNLKL---KQENEKSQHLKEIEALKAKLLEVT---E 660
Cdd:TIGR02169  173 EKALEELEE-----VEENIERLdliiDEKRQQLERLRREREKAERYQALlkeKREYEGYELLKEKEALERQKEAIErqlA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  661 EKEQTLENLKAKLESVEDQhLVEMEDTLNKLqEAEIKVK---ELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 737
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKR-LEEIEQLLEEL-NKKIKDLgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  738 ansEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKft 817
Cdd:TIGR02169  326 ---KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE-- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  818 savdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSS 897
Cdd:TIGR02169  401 ------------INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  898 AQLMKMNDELRLKERQLEQIQLELTKAnekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ-- 975
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRELAEA-----EAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIev 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  976 ---------------------NQYKDLQA---------KYEKETSEMITKHDADIKGFKQNLLDAE-------------- 1011
Cdd:TIGR02169  544 aagnrlnnvvveddavakeaiELLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDpkyepafkyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1012 ---EALKAAQKKNDE--LETQAEELKKQ-------AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLE 1079
Cdd:TIGR02169  624 lvvEDIEAARRLMGKyrMVTLEGELFEKsgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1080 KESLLSQHLEMESKILLVQQDREELwtkNEELNSENKKIlkqkEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLK 1159
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERL----EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1160 ITQENDALRSSESTllQQLKELQANKDAVDvacqkhikereelehyqklleendrvikdkdDVIQRLQSSYDDLARNQRE 1239
Cdd:TIGR02169  777 LEEALNDLEARLSH--SRIPEIQAELSKLE-------------------------------EEVSRIEARLREIEQKLNR 823

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1240 LLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQT 1319
Cdd:TIGR02169  824 LTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1320 ELETEREKLEKMTKDNMDLKASLSSLSNFLEEM-KSSREASNSEKIHLLQEALFASEQRLLAEREEL--VNeNKAVTE-K 1395
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIeDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepVN-MLAIQEyE 982

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359622 1396 LTKATAD------AVLAE--TAFTEKINELNLEKESVFSKSlqFEKHNE 1436
Cdd:TIGR02169  983 EVLKRLDelkekrAKLEEerKAILERIEEYEKKKREVFMEA--FEAINE 1029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 682-1628 2.70e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 2.70e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  682 VEMEDTLNKLQEAEIKVKELDVLQAKCNEQTkligsltQQIRASEEKLLDLAALQKanSEGKLEIQKLSEQLQAAEKQIQ 761
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQL-------ERLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  762 NLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQllkekftsavDGAENAQRAMQETINKLnqke 841
Cdd:TIGR02169  241 AIERQ-------LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK----------DLGEEEQLRVKEKIGEL---- 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  842 eqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlkERQLEQIQLEL 921
Cdd:TIGR02169  300 ------EAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL---------------------EREIEEERKRR 352

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  922 TKANEKAVQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmITKHDADIK 1001
Cdd:TIGR02169  353 DKLTEEYAELKEELEDLRAELEE-VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-LADLNAAIA 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1002 GFKQNLLDAEEalkaaqkkndELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKE 1081
Cdd:TIGR02169  431 GIEAKINELEE----------EKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1082 SLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQE---STEKVAliSEKSKLLSEIETAQADLL 1158
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNvvvEDDAVA--KEAIELLKRRKAGRATFL 578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1159 KITQENDALRssestLLQQLKELQANKDAVD-VACQKHIKER-----------EELEHYQKLLEENDRV-----IKDKDD 1221
Cdd:TIGR02169  579 PLNKMRDERR-----DLSILSEDGVIGFAVDlVEFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKYRMVtlegeLFEKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1222 VIQRLQSSYDDLARNQRELLQEVSILTAERDSaqekdldlksthiaLKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLA 1301
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1302 NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKssreasnsEKIHLLQEALFASEQRLLAE 1381
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE--------EDLHKLEEALNDLEARLSHS 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1382 R-----------EELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYS 1450
Cdd:TIGR02169  792 RipeiqaelsklEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1451 ELLDEKKSLENAFSDMKREqeldfsakrllvqenttlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLE 1530
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKE---------------------RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1531 NELAAVSHAKQVLSSSfNTCSSDIEILNRERTELQDKCQKLtGEVeNMKEnltvekkarILDKESFLLERMELQNNIGFL 1610
Cdd:TIGR02169  931 EELSEIEDPKGEDEEI-PEEELSLEDVQAELQRVEEEIRAL-EPV-NMLA---------IQEYEEVLKRLDELKEKRAKL 998

                          970
                   ....*....|....*...
gi 2024359622 1611 EKEVEEMREKNKEFLTEK 1628
Cdd:TIGR02169  999 EEERKAILERIEEYEKKK 1016
PTZ00121 PTZ00121
MAEBL; Provisional
 520-1320 7.04e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 77.87  E-value: 7.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  520 KEHQREMSSLKEKFESSEEALRKEiktlsasnerMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKV 599
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTE----------TGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKR 1153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  600 SFNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKakllevTEEKEQTLENLKAKLESVEDQ 679
Cdd:PTZ00121  1154 VEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAAR------KAEEERKAEEARKAEDAKKAE 1227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  680 HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 759
Cdd:PTZ00121  1228 AVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  760 IQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLN- 838
Cdd:PTZ00121  1308 KKKAEEAK-----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADa 1382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  839 -QKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndiaEIMKS-SGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:PTZ00121  1383 aKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE----EKKKAdEAKKKAEEAKKADEAKKKAEEAKK 1458

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 IQLELTKANEKavqlqKNVEQTAQKAEQSQQ-ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 995
Cdd:PTZ00121  1459 AEEAKKKAEEA-----KKADEAKKKAEEAKKaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  996 HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEElKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNT 1075
Cdd:PTZ00121  1534 KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE-AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1076 LKLEKESLLSQHL----EMESKILLVQQDREELWTKNEELN--SENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSE 1149
Cdd:PTZ00121  1613 KKAEEAKIKAEELkkaeEEKKKVEQLKKKEAEEKKKAEELKkaEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1150 IETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQS 1228
Cdd:PTZ00121  1693 ALKKEAEEAKKAEELKKKEAEEKKKAEELkKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEE 1772

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1229 syddlARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQ 1308
Cdd:PTZ00121  1773 -----IRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEAD 1847

                          810
                   ....*....|..
gi 2024359622 1309 ALKLRKDEMQTE 1320
Cdd:PTZ00121  1848 AFEKHKFNKNNE 1859
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 347-1131 9.99e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.42  E-value: 9.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  347 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlEMEAKMDQLRAMVEAAdrekVELLNQLEE 424
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELE-----------KLTEEISELEKRLEEI----EQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  425 E-KRKVEDLQFRVEEE-SITKGDLER-KRQISEDPENVATVSEKSRIMELERDLALRvkEVAELRGRLESSKHIDDvdts 501
Cdd:TIGR02169  280 KiKDLGEEEQLRVKEKiGELEAEIASlERSIAEKERELEDAEERLAKLEAEIDKLLA--EIEELEREIEEERKRRD---- 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  502 lSLLQEISSLQEKMAAAgkehQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwKS 581
Cdd:TIGR02169  354 -KLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADL-NA 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  582 KLESAIASHQQAMEELKVSFNKgVGAQTAEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKL------ 655
Cdd:TIGR02169  428 AIAGIEAKINELEEEKEDKALE-IKKQEWKLEQLAADLSKYEQELYDLKEEYD-RVEKELSKLQRELAEAEAQAraseer 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  656 -------LEVTEEKEQTLENLKAKLESVEDQHLVEMEDTL-NKLQEAeikVKELDVLQAKCNEQTKL--IGSLT-QQIRA 724
Cdd:TIGR02169  506 vrggravEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAgNRLNNV---VVEDDAVAKEAIELLKRrkAGRATfLPLNK 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  725 SEEKLLDLAALQKANSEG-KLEIQKLSEQLQAAEKQI-------QNLETEK-VGGSSKVSNLTKEL-------------- 781
Cdd:TIGR02169  583 MRDERRDLSILSEDGVIGfAVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARrLMGKYRMVTLEGELfeksgamtggsrap 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  782 QGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM 861
Cdd:TIGR02169  663 RGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  862 ETKLKereEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND-ELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 940
Cdd:TIGR02169  743 EEDLS---SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQ 819

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  941 K------AEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEAL 1014
Cdd:TIGR02169  820 KlnrltlEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE-LEELEAALRDLESRLGDLKKERDELEAQL 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1015 KAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEK---ETLAQERNTLKLEKESLLSQHLEME 1091
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAI 978

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 2024359622 1092 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQ 1131
Cdd:TIGR02169  979 QEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 745-1351 1.86e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 76.21  E-value: 1.86e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  745 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAE 824
Cdd:TIGR04523   41 KLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKN 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  825 NAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 904
Cdd:TIGR04523  121 KLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  905 ---DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKdl 981
Cdd:TIGR04523  201 lllSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTE-ISNTQTQLNQLKDEQNKIKKQLSEKQKELE-- 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  982 qakyekETSEMITKHDADIKGFKQNLLDAEEalkaaQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD 1061
Cdd:TIGR04523  278 ------QNNKKIKELEKQLNQLKSEISDLNN-----QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1062 LISEKETLAQERNTLKLEKEsllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS 1141
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELE-------EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1142 EKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDA----VDVACQKHIKEREELEHYQKLLEENDRVIK 1217
Cdd:TIGR04523  420 EKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESletqLKVLSRSINKIKQNLEQKQKELKSKEKELK 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1218 DKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS---------THIALKNEIDCLLQTNRSLQSEKEM 1288
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddfelKKENLEKEIDEKNKEIEELKQTQKS 579

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622 1289 LLKSREELCVSLANTANENQALK---LRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEE 1351
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIkeiEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQ 645
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 398-1201 2.87e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.93  E-value: 2.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  398 EAKMDQLRAMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitkgDLERKRQISEDpENVATVSEKSRIMELERDlal 477
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN----ELHEKQKFYLR-QSVIDLQTKLQEMQMERD--- 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  478 rvkEVAELRGRLESSKH--IDDVDTSLSLLQEISSLQEKMAaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMG 555
Cdd:pfam15921  128 ---AMADIRRRESQSQEdlRNQLQNTVHELEAAKCLKEDML---EDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  556 K---ENESLKTkldhankensdvieLWKSKLESAIASHQQAMEElKVSFNKGvgaqtaEFAELKTQMEKVKLDYENEMSN 632
Cdd:pfam15921  202 KkiyEHDSMST--------------MHFRSLGSAISKILRELDT-EISYLKG------RIFPVEDQLEALKSESQNKIEL 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  633 LKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQ----------HLVEMEDTLNKLQEA-------- 694
Cdd:pfam15921  261 LLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQarnqnsmymrQLSDLESTVSQLRSElreakrmy 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  695 EIKVKELDVLQAKCNeqTKLIGSLTQQIRASEEKLLDLAALQKANSEgkleIQKLSEQLQAAEKQIQNLETEKVGGSSKV 774
Cdd:pfam15921  341 EDKIEELEKQLVLAN--SELTEARTERDQFSQESGNLDDQLQKLLAD----LHKREKELSLEKEQNKRLWDRDTGNSITI 414

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  775 SNLTKELQGKEQKLLDLEKNLSAvnqvkdsLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEqfaLMSSELEQL 854
Cdd:pfam15921  415 DHLRRELDDRNMEVQRLEALLKA-------MKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKE---MLRKVVEEL 484

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  855 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN------DELRLKERQLEQIQLELTKANEKA 928
Cdd:pfam15921  485 TAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQhlknegDHLRNVQTECEALKLQMAEKDKVI 564

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  929 VQLQKNVEQTAQKAEQsQQETLKTHQEELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEMITKHdADIKGFKQNLL 1008
Cdd:pfam15921  565 EILRQQIENMTQLVGQ-HGRTAGAMQVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIRELEARV-SDLELEKVKLV 638

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1009 DA-EEALKAA----QKKN---DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMR-DLISEKETLAQERNTLKle 1079
Cdd:pfam15921  639 NAgSERLRAVkdikQERDqllNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQTRNTLK-- 716

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1080 kesllSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRqestEKVALISEKSKLLSEIETAQADLLK 1159
Cdd:pfam15921  717 -----SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANK----EKHFLKEEKNKLSQELSTVATEKNK 787

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 2024359622 1160 ITQENDALRSSESTLLQQLKELQANKDAVDVA---CQKHIKEREE 1201
Cdd:pfam15921  788 MAGELEVLRSQERRLKEKVANMEVALDKASLQfaeCQDIIQRQEQ 832
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-973 3.96e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.36  E-value: 3.96e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  343 ALQEALKEKQqhIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlemeakmdQLRAMVEAADREKVELLNQL 422
Cdd:COG1196    217 ELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELE------------------ELEAELAELEAELEELRLEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 EEEKRKVEDLQFRVEEESITKGDLERKRQisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLEsskhiddvdtsl 502
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIA-----------RLEERRRELEERLEELEEELAELEEELE------------ 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  503 SLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSK 582
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAE--EA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  583 LESAIASHQQAMEELKVSfnkgvgAQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEK 662
Cdd:COG1196    412 LLERLERLEEELEELEEA------LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  663 EQTLENLKAKLESVEDQHLVEMEDTLNKLQEA-------EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAL 735
Cdd:COG1196    486 LAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglagAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEY 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  736 QKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS----LEKELQL 811
Cdd:COG1196    566 LKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAalrrAVTLAGR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  812 LKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 891
Cdd:COG1196    646 LREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  892 SSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK----------AEQSQQETlkthQEELKKMQ 961
Cdd:COG1196    726 LEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREiealgpvnllAIEEYEEL----EERYDFLS 801

                          650
                   ....*....|..
gi 2024359622  962 DQLTDMKKQMET 973
Cdd:COG1196    802 EQREDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1315-2082 4.57e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.10  E-value: 4.57e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1315 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREasNSEKIHLLQEALFASEQRLLA-EREELVNENKAVT 1393
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--KAERYQALLKEKREYEGYELLkEKEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1394 EKLtkATADAVLAEtaFTEKINELNLEKESVFSKSLQFEKHNEALLR-EKDELERKYSELLDEKKSLENAFSDMKREQEL 1472
Cdd:TIGR02169  244 RQL--ASLEEELEK--LTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1473 DFSAKRLLVQENTTLKYSIEALEEELKKKNLEnqeliacRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1552
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAEIEELEREIEEERKR-------RDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1553 DIEILNRERTE-------LQDKCQKLTGEVENMKENLTVeKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFL 1625
Cdd:TIGR02169  393 KLEKLKREINElkreldrLQEELQRLSEELADLNAAIAG-IEAKINELEE---EKEDKALEIKKQEWKLEQLAADLSKYE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1626 TEKELLVQEKEKSETKLEEVIKEkmILYKETEQLASKIEQLKSDFTSLsVSKAELEDVHSCVSvMLDELQHKY------- 1698
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQRE--LAEAEAQARASEERVRGGRAVEE-VLKASIQGVHGTVA-QLGSVGERYataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1699 ------------EVTEKEKMELVQENESLHAEWKSLVIINEEiLKEKEKLSK-----------EYYKLHEKVVA------ 1749
Cdd:TIGR02169  545 agnrlnnvvvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEdgvigfavdlvEFDPKYEPAFKyvfgdt 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1750 -LLEQTDAD----FSCRLLVSEGKhelLLEE---MSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAI 1821
Cdd:TIGR02169  624 lVVEDIEAArrlmGKYRMVTLEGE---LFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1822 HQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEE 1901
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1902 NVKLAEELGRSR-DEVTSH-QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEI----------DEERASLQKSISDTS 1969
Cdd:TIGR02169  781 LNDLEARLSHSRiPEIQAElSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIqelqeqridlKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1970 ALITQKDEELEKLRNEITVLRGEnasAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQDE 2049
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESR---LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937

                          810       820       830
                   ....*....|....*....|....*....|...
gi 2024359622 2050 SAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2082
Cdd:TIGR02169  938 DPKGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1099-2021 2.75e-12

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 72.77  E-value: 2.75e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1099 QDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL 1178
Cdd:TIGR00606  206 QMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDN 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1179 KELQANKDAVDVACQKHIKEREEleHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSI--LTAERDSAQE 1256
Cdd:TIGR00606  286 SELELKMEKVFQGTDEQLNDLYH--NHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqLQADRHQEHI 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1257 KDLDLKSTHIALKNEIDCLLQ---TNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1333
Cdd:TIGR00606  364 RARDSLIQSLATRLELDGFERgpfSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIE 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1334 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEK 1413
Cdd:TIGR00606  444 LKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQE 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1414 INELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDE------KKSLENAFSDMKREQ---ELDFSAKRLLVQEN 1484
Cdd:TIGR00606  524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLlgyfpnKKQLEDWLHSKSKEInqtRDRLAKLNKELASL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1485 TTLKYSIEALEEELKKKNLENQELI-------ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEIL 1557
Cdd:TIGR00606  604 EQNKNHINNELESKEEQLSSYEDKLfdvcgsqDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVC 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1558 NR------ERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELL 1631
Cdd:TIGR00606  684 QRvfqteaELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1632 VQEKEKSETKLEEVIKEkmilyketEQLAskiEQLKSDFTSLSVSKAELEDVhscvsvmldelqhkyevtEKEKMELVQE 1711
Cdd:TIGR00606  764 KNDIEEQETLLGTIMPE--------EESA---KVCLTDVTIMERFQMELKDV------------------ERKIAQQAAK 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1712 NESLhaewkSLVIINEEILKEKEKLSKEYYKLHEKVvALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQA 1791
Cdd:TIGR00606  815 LQGS-----DLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEE 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1792 QTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNnLKNEEELTKSKELLNLEN 1871
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK-VKNIHGYMKDIENKIQDG 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1872 KKVEELKKEFEALKLAAaqksqQLAALQEENVKLAEELGRSRDEVTSHQKLEeerSVLNNQLLEMKkslpsntlRESTLK 1951
Cdd:TIGR00606  968 KDDYLKQKETELNTVNA-----QLEECEKHQEKINEDMRLMRQDIDTQKIQE---RWLQDNLTLRK--------RENELK 1031

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1952 kEIDEERASLQKSISDTSalITQKDEELEKLRNEITVLRGENASAKTLQsvvKTLESDKLKLEEKVKNLE 2021
Cdd:TIGR00606 1032 -EVEEELKQHLKEMGQMQ--VLQMKQEHQKLEENIDLIKRNHVLALGRQ---KGYEKEIKHFKKELREPQ 1095
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 632-1233 5.60e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 71.20  E-value: 5.60e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  632 NLKLKQENEKSQHLKEIEALKAKLlevtEEKEQTLENL-KAKLESVEDQHLVEMEDTLNKLQEAEIKVKE------LDVL 704
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNEL----KNKEKELKNLdKNLNKDEEKINNSNNKIKILEQQIKDLNDKLkknkdkINKL 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  705 QAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKL-----------EIQKLSEQLQAAEKQIQNLETEKVGGSSK 773
Cdd:TIGR04523  102 NSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDkflteikkkekELEKLNNKYNDLKKQKEELENELNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  774 VSNLTKELQGKEQKLLDLEKNLS---AVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSE 850
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLSnlkKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDE 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  851 LEQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK-MNDELRLKERQLEQIQLELTKANEKAV 929
Cdd:TIGR04523  262 QNKIKKQL---SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKeLKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  930 QLQKNVEQTAQKAEQSQQETLKThQEELKKMQDQLTDMKKQmetsQNQYKDLQAKYEKETSEMITKhdadIKGFKQNLLD 1009
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEK-QRELEEKQNEIEKLKKE----NQSYKQEIKNLESQINDLESK----IQNQEKLNQQ 409

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1010 AEEALKAAQKKNDELETQAEELK----KQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLS 1085
Cdd:TIGR04523  410 KDEQIKKLQQEKELLEKEIERLKetiiKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQK 489

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1086 QHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISE---------KSKLLSEIETAQAD 1156
Cdd:TIGR04523  490 ELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDElnkddfelkKENLEKEIDEKNKE 569

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359622 1157 LLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIkdkDDVIQRLQSSYDDL 1233
Cdd:TIGR04523  570 IEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKL---SSIIKNIKSKKNKL 643
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 215-275 6.01e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 70.87  E-value: 6.01e-12
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622  215 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPRYGLF 275
Cdd:COG5244      4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 348-961 9.10e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.92  E-value: 9.10e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  348 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALVRDG-------HDRHVLEMEAKMDQLRAMVEAADREKV 416
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  417 ELLNQLEEekrkvedlQFRVEEESITKGDLERKrQISEDPENVatvseKSRIMELERDLALRVKEVAELRgrlESSKHID 496
Cdd:pfam15921  342 DKIEELEK--------QLVLANSELTEARTERD-QFSQESGNL-----DDQLQKLLADLHKREKELSLEK---EQNKRLW 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  497 DVDTSLSLlqEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENeSLKTKLDHANKENSDVI 576
Cdd:pfam15921  405 DRDTGNSI--TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVS-SLTAQLESTKEMLRKVV 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKlESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVkldyenemsNLKLKQenekSQHLKEiealkakll 656
Cdd:pfam15921  482 EELTAK-KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV---------DLKLQE----LQHLKN--------- 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  657 evteeKEQTLENLKAKLESVedqhlvemedtlnKLQEAEiKVKELDVLQAKCNEQTKLIGsltQQIRASEEKLLDLAALQ 736
Cdd:pfam15921  539 -----EGDHLRNVQTECEAL-------------KLQMAE-KDKVIEILRQQIENMTQLVG---QHGRTAGAMQVEKAQLE 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  737 KANSEGKLEIQKLS-------EQLQAAEKQIQNLETEKV----GGSSKVSNLTKELQGKEQKLLDLEKNLSAVNqvkdSL 805
Cdd:pfam15921  597 KEINDRRLELQEFKilkdkkdAKIRELEARVSDLELEKVklvnAGSERLRAVKDIKQERDQLLNEVKTSRNELN----SL 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  806 EKELQLLKEKFTSAVDGAE-----------NAQRAMQETINKLNQKE--------------EQFALMSSELEQLKSNLTV 860
Cdd:pfam15921  673 SEDYEVLKRNFRNKSEEMEtttnklkmqlkSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQSKIQF 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  861 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLmkmnDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ 940
Cdd:pfam15921  753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL----EVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650       660
                   ....*....|....*....|.
gi 2024359622  941 KAEQSQQETLKTHQEELKKMQ 961
Cdd:pfam15921  829 RQEQESVRLKLQHTLDVKELQ 849
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 452-1219 2.72e-11

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 69.48  E-value: 2.72e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  452 ISEDPENVATVSEKSRiMELERDLALRVKEVAELRGRLESSKHIDDVDTSLSLLQEISSLQEKMaaagKEHQREMSSLKE 531
Cdd:pfam12128  205 ILEDDGVVPPKSRLNR-QQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGY----KSDETLIASRQE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  532 KFESSEEALRKEIKTLSAS-NERMGKENESLKT-KLDHANKENS-DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQ 608
Cdd:pfam12128  280 ERQETSAELNQLLRTLDDQwKEKRDELNGELSAaDAAVAKDRSElEALEDQHGAFLDADIETAAADQEQLPSWQSELENL 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  609 TAEFAELKTQMEKVKLDYENEMSNLKlkqenekSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTL 688
Cdd:pfam12128  360 EERLKALTGKHQDVTAKYNRRRSKIK-------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGK 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  689 NKLQEAEIKVK----ELDVLQAkcneqtkligsltqQIRASEEKLLDLAALQKansegklEIQKLSEQLQAAEKQIQNLE 764
Cdd:pfam12128  433 LEFNEEEYRLKsrlgELKLRLN--------------QATATPELLLQLENFDE-------RIERAREEQEAANAEVERLQ 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  765 TEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS--------LEKELQLLKEKFTSAVDGA-----------EN 825
Cdd:pfam12128  492 SELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPqagtllhfLRKEAPDWEQSIGKVISPEllhrtdldpevWD 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  826 AQRAMQETINKLNQKEEQFALMSSEL--EQLKSNLTVMETKLKEREEREQQLTEAKVKLendiaeimkssgdsSAQLMKM 903
Cdd:pfam12128  572 GSVGGELNLYGVKLDLKRIDVPEWAAseEELRERLDKAEEALQSAREKQAAAEEQLVQA--------------NGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  904 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMetsQNQYKDLQA 983
Cdd:pfam12128  638 SREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQ---KEQKREART 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  984 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKkndELETQ-AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL 1062
Cdd:pfam12128  715 EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELK---ALETWyKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRR 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1063 ISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDreeLWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISE 1142
Cdd:pfam12128  792 QEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQ---LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1143 KSKLLSeietaqadlLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHI---------KEREEL-EHYQKlLEEN 1212
Cdd:pfam12128  869 MSKLAT---------LKEDANSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVehfknviadHSGSGLaETWES-LREE 938


                   ....*..
gi 2024359622 1213 DRVIKDK 1219
Cdd:pfam12128  939 DHYQNDK 945
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 620-1162 5.91e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 67.74  E-value: 5.91e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  620 EKVKLDYENEmsnlKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKlesveDQHLVEMEDTLNKLQEAEIKVK 699
Cdd:TIGR04523  165 KKQKEELENE----LNLLEKEKLNIQKNIDKIKNKLLK----LELLLSNLKKK-----IQKNKSLESQISELKKQNNQLK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  700 E-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLD----LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKv 774
Cdd:TIGR04523  232 DnIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  775 sNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQL 854
Cdd:TIGR04523  311 -ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  855 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 934
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  935 VEQTAQKAEQSQQeTLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyEKETSEMITKHDADIKGFKQNLLDAEEAL 1014
Cdd:TIGR04523  470 LKVLSRSINKIKQ-NLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK-ISSLKEKIEKLESEKKEKESKISDLEDEL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1015 KA--AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdkmrDLISEKETlaqerntlklEKESLLSQHLEMES 1092
Cdd:TIGR04523  548 NKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ-------ELIDQKEK----------EKKDLIKEIEEKEK 610

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1093 KILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQ 1162
Cdd:TIGR04523  611 KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIE 680
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
332-891 7.19e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 7.19e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  332 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVrDGHDRHVLEMEAKMDQLRAMVEAA 411
Cdd:PRK03918   179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  412 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENvaTVSEKSRIMELERDLALRVKEVAELRGRLES 491
Cdd:PRK03918   258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE--YLDELREIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  492 SKhiddvdtslsllQEISSLQEKMaaagKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 571
Cdd:PRK03918   336 KE------------ERLEELKKKL----KELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKA 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  572 NSDvIELWKSKLESAIASHQQAMEELKVSFNKgvgaqtAEFAELKTQMEKVKLDYENEmsnlklkqENEKSQHLKEIEAL 651
Cdd:PRK03918   400 KEE-IEEEISKITARIGELKKEIKELKKAIEE------LKKAKGKCPVCGRELTEEHR--------KELLEEYTAELKRI 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  652 KAKLLEvTEEKEQTLENLKAKLESV--EDQHLVEMEDTLNKLQEAEIKVKELDV--LQAKCNEQTKL---IGSLTQQIRA 724
Cdd:PRK03918   465 EKELKE-IEEKERKLRKELRELEKVlkKESELIKLKELAEQLKELEEKLKKYNLeeLEKKAEEYEKLkekLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  725 SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDS 804
Cdd:PRK03918   544 LKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV---EELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  805 LEKELQLLKEKFtSAVDGAENAQRAMQETINKLNQK--EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL 882
Cdd:PRK03918   621 LKKLEEELDKAF-EELAETEKRLEELRKELEELEKKysEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699


                   ....*....
gi 2024359622  883 ENDIAEIMK 891
Cdd:PRK03918   700 KEELEEREK 708
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1730-2029 8.04e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 8.04e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1730 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQ 1809
Cdd:COG1196    218 LKEELKELEAELLLLKLRELEAELEEL---------EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1810 TMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAA 1889
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1890 QKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTS 1969
Cdd:COG1196    369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1970 ALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSE 2029
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE 508
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 421-1262 8.09e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 67.69  E-value: 8.09e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  421 QLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKHiddvDT 500
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQ----EL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  501 SLSLLQEISSLQEKMAAAGKEHQREMSSLKEkfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWK 580
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKE--EEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  581 SKLESAIASHQQAMEELKVSfNKGVGAQTAEFAELKTQMEKVKLDYENEMSNLKLKQEnEKSQHLKEIEALKAKLLEVTE 660
Cdd:pfam02463  324 KKAEKELKKEKEEIEELEKE-LKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK-LESERLSSAAKLKEEELELKS 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  661 EKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEiKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANS 740
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE-ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  741 EGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAV 820
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  821 DGAENAQRAMQETINKLNQKEE--QFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGD--- 895
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLliPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLkes 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  896 -----SSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQS--QQETLKTHQEELKKMQDQLTDMK 968
Cdd:pfam02463  641 akakeSGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILrrQLEIKKKEQREKEELKKLKLEAE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  969 KQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1048
Cdd:pfam02463  721 ELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1049 RKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELN---SENKKILKQKEAA 1125
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITkeeLLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1126 EAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHY 1205
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359622 1206 QKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvsILTAERDSAQEKDLDLK 1262
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE--RLEEEKKKLIRAIIEET 1015
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1310-1988 9.36e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.45  E-value: 9.36e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSRE---ASNSEKIHLLQEALFASEQRLLAEREELV 1386
Cdd:pfam15921  115 LQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEdmlEDSNTQIEQLRKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1387 NENKAVTEKLTKATADAVL----AETAFTEKINELNLEKESVFSKSLQFEKHNEALlreKDELERKYSELLDEKKS-LEN 1461
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMhfrsLGSAISKILRELDTEISYLKGRIFPVEDQLEAL---KSESQNKIELLLQQHQDrIEQ 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1462 AFSDMKRE-QELDFSAKRLLVQENTtLKYSIEALEEELKKKN-LENQELIACRSDLSDLLKEAQDARRTLENELAAVSHA 1539
Cdd:pfam15921  272 LISEHEVEiTGLTEKASSARSQANS-IQSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQ 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1540 KQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKA-------------------RILDKESFLLER 1600
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitidhlrRELDDRNMEVQR 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1601 MEL------QNNIGFLEKEVEEMREKNKEFLTEKELLVQ---EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1671
Cdd:pfam15921  431 LEAllkamkSECQGQMERQMAAIQGKNESLEKVSSLTAQlesTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKER 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1672 SLSVSKAELEDVHSCVSVMLDELQHKYevTEKEKMELVQ---ENESLHAEWKSLVIineEILKEKEKLSKEYYKLHEKVV 1748
Cdd:pfam15921  511 AIEATNAEITKLRSRVDLKLQELQHLK--NEGDHLRNVQtecEALKLQMAEKDKVI---EILRQQIENMTQLVGQHGRTA 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1749 ALLEQTDADFSCRLlvseGKHELLLEEMSNLA----LKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqe 1824
Cdd:pfam15921  586 GAMQVEKAQLEKEI----NDRRLELQEFKILKdkkdAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQL--- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1825 kietLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE-ELKK-----------EFEALKLAAAQKS 1892
Cdd:pfam15921  659 ----LNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQsELEQtrntlksmegsDGHAMKVAMGMQK 734

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1893 Q------QLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLNNQL-------------LEMKKSlPSNTLRESTLKKE 1953
Cdd:pfam15921  735 QitakrgQIDALQSKIQFLEEAMTNANKE---KHFLKEEKNKLSQELstvateknkmageLEVLRS-QERRLKEKVANME 810

                          730       740       750
                   ....*....|....*....|....*....|....*
gi 2024359622 1954 IDEERASLQksISDTSALITQKDEELEKLRNEITV 1988
Cdd:pfam15921  811 VALDKASLQ--FAECQDIIQRQEQESVRLKLQHTL 843
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 932-1509 1.08e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 66.97  E-value: 1.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  932 QKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQaKYEKETSEMITKHDADIKGFKQNLLDAE 1011
Cdd:TIGR04523   31 QDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE-QQIKDLNDKLKKNKDKINKLNSDLSKIN 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1012 EALKAAQKKNDELETQAEELKKQAEQAKSL----SSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQH 1087
Cdd:TIGR04523  110 SEIKNDKEQKNKLEVELNKLEKQKKENKKNidkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1088 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEaaeaKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDAL 1167
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKK----QNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1168 RSSESTLLQQLKELQANKDAVDVACQKHIKEREEL--EHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVS 1245
Cdd:TIGR04523  266 KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLnnQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1246 ILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETER 1325
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1326 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEalfaseqrlLAEREELVNENKAVTEKLTKATADAVL 1405
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ---------LKVLSRSINKIKQNLEQKQKELKSKEK 496

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1406 AETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRL--LVQE 1483
Cdd:TIGR04523  497 ELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIeeLKQT 576

                          570       580
                   ....*....|....*....|....*.
gi 2024359622 1484 NTTLKYSIEALEEELKKKNLENQELI 1509
Cdd:TIGR04523  577 QKSLKKKQEEKQELIDQKEKEKKDLI 602
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
710-1226 1.25e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.01  E-value: 1.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  710 EQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLL 789
Cdd:PRK03918   197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKDSLEK--ELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE 867
Cdd:PRK03918   277 ELEEKVKELKELKEKAEEyiKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  868 REEREQQLTEAKVKLENdIAEIMKSSGDSSAQlmKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ- 946
Cdd:PRK03918   357 LEERHELYEEAKAKKEE-LERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKk 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  947 ---------QETLKTHQEEL-KKMQDQLTDMKKQMETSQNQYKDLQAkyEKETSEMITKHDADIKGFKQNLLDAEEALKA 1016
Cdd:PRK03918   434 akgkcpvcgRELTEEHRKELlEEYTAELKRIEKELKEIEEKERKLRK--ELRELEKVLKKESELIKLKELAEQLKELEEK 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 AQKKN-DELETQAEELKKQAEQAKSLS---SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESL-LSQHLEME 1091
Cdd:PRK03918   512 LKKYNlEELEKKAEEYEKLKEKLIKLKgeiKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELgFESVEELE 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1092 SKIllvqQDREELWTKNEELnSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEND------ 1165
Cdd:PRK03918   592 ERL----KELEPFYNEYLEL-KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeelre 666

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622 1166 ---ALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRL 1226
Cdd:PRK03918   667 eylELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 786-1002 1.42e-10

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 65.56  E-value: 1.42e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  786 QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKL 865
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  866 KEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN--------------DELRLKERQLEQIQLELTKANEKAVQL 931
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLqylkylaparreqaEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622  932 QKNVEQ---TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKG 1002
Cdd:COG4942    180 LAELEEeraALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKG 253
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 813-1630 3.19e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 3.19e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  813 KEKFTSAVDGAENAQRAMQETINKLNQ-KEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQltEAKVKLEND 885
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNElHEKQKFYLRQSVIDLQTKLQEMQMErdamadIRRRESQSQE--DLRNQLQNT 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  886 IAEI----------MKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQ-QETLKTHQ 954
Cdd:pfam15921  151 VHELeaakclkedmLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAiSKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  955 EELKKMQDQLTDMKKQMET----SQNQYKDLQAKYEKETSEMITKHDADIKGFKqnlldaeEALKAAQKKNDELETQAEE 1030
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEAlkseSQNKIELLLQQHQDRIEQLISEHEVEITGLT-------EKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1031 LKKQAEQAKSLSsvlasarkeielmsdkMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1110
Cdd:pfam15921  304 IQEQARNQNSMY----------------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQ 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1111 LNSENKKILKQKEAAEAKSRQESTEkVALISEKSKLLSEIETAQADLLkitqenDALRSSESTLLQQLKELQANKDAVDV 1190
Cdd:pfam15921  368 FSQESGNLDDQLQKLLADLHKREKE-LSLEKEQNKRLWDRDTGNSITI------DHLRRELDDRNMEVQRLEALLKAMKS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1191 ACQKHIKER--------EELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQREllqeVSILTAerdSAQEKDLDLK 1262
Cdd:pfam15921  441 ECQGQMERQmaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERT----VSDLTA---SLQEKERAIE 513

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1263 STH---IALKNEIDCLLQTNRSLQSEKEmllksreelcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKdnmdlk 1339
Cdd:pfam15921  514 ATNaeiTKLRSRVDLKLQELQHLKNEGD-----------HLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQ------ 576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1340 aslsslsnFLEEMKSSREASNSEKIHLLQEalfASEQRLlaEREELvnenkavteKLTKATADAVLAEtaFTEKINELNL 1419
Cdd:pfam15921  577 --------LVGQHGRTAGAMQVEKAQLEKE---INDRRL--ELQEF---------KILKDKKDAKIRE--LEARVSDLEL 632

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1420 EKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-----EQELDFSAKRL----------LVQEN 1484
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnkSEEMETTTNKLkmqlksaqseLEQTR 712

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1485 TTLKySIEALEEELKKKNLENQELIACRSDLSDLLkeaQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTEL 1564
Cdd:pfam15921  713 NTLK-SMEGSDGHAMKVAMGMQKQITAKRGQIDAL---QSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622 1565 QDKCQKLTGEVENMKENLTVEKKAriLDKESflLERMELQNNIGflEKEVEEMREKNKEFLTEKEL 1630
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVA--LDKAS--LQFAECQDIIQ--RQEQESVRLKLQHTLDVKEL 848
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1197-2025 3.37e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 3.37e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1197 KEREELEHYQKLLEENDRVIKDKDDVIQRLQSsyddlarnqrellqevsiltaERDSAqEKDLDLKSTHIalKNEIDCLL 1276
Cdd:TIGR02169  174 KALEELEEVEENIERLDLIIDEKRQQLERLRR---------------------EREKA-ERYQALLKEKR--EYEGYELL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1277 QTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM-DLKASLSSLSNFLEEMKSS 1355
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlRVKEKIGELEAEIASLERS 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1356 REASNSEKIHLLQEA--LFASEQRLLAEREEL---VNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQ 1430
Cdd:TIGR02169  310 IAEKERELEDAEERLakLEAEIDKLLAEIEELereIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKD 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1431 FEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK----KKNLENQ 1506
Cdd:TIGR02169  390 YREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEqlaaDLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1507 ELIACRSDLSDLLKEAQDARRtlenELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLtGEVE---------- 1576
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQR----ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQL-GSVGeryataieva 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1577 --NMKENLTVEK-----------KARILDKESFL-----------LERMELQNNIGFLEKEVEEMREKNKEFL------- 1625
Cdd:TIGR02169  545 agNRLNNVVVEDdavakeaiellKRRKAGRATFLplnkmrderrdLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtl 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1626 ------TEKELLVQ-----------EKEKSET----KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvh 1684
Cdd:TIGR02169  625 vvedieAARRLMGKyrmvtlegelfEKSGAMTggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIEN-- 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1685 scvsvMLDELQHKYEVTEKEKMELVQENESLHAEwkslviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLlv 1764
Cdd:TIGR02169  703 -----RLDELSQELSDASRKIGEIEKEIEQLEQE--------EEKLKERLEELEEDLSSLEQEIENVKSELKELEARI-- 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1765 segkhELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA-EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQ 1843
Cdd:TIGR02169  768 -----EELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1844 NELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLE 1923
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENL----------NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI---EELE 909

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1924 EERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEEraslqKSISDTSALITQKDEELEKLRNEITVLRGENASA------- 1996
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGED-----EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAiqeyeev 984

                          890       900       910
                   ....*....|....*....|....*....|...
gi 2024359622 1997 ----KTLQSVVKTLESDKLKLEEKVKNLEQKLK 2025
Cdd:TIGR02169  985 lkrlDELKEKRAKLEEERKAILERIEEYEKKKR 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1611-2025 4.05e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.47  E-value: 4.05e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1611 EKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM 1690
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEER 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1691 LDELQHKYEVTEkEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQtdadfscrllvsegkhe 1770
Cdd:PRK03918   268 IEELKKEIEELE-EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEER----------------- 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1771 llLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLaslensrqtnEKLQNELDMLK 1850
Cdd:PRK03918   330 --IKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTP----------EKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1851 QNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEEN-----VKLAEELGRSRDEVtshQKLEEE 1925
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkellEEYTAELKRIEKEL---KEIEEK 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1926 RSVLNNQLLEMKKSLpSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2005
Cdd:PRK03918   475 ERKLRKELRELEKVL-KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          410       420
                   ....*....|....*....|
gi 2024359622 2006 LESDKLKLEEKVKNLEQKLK 2025
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELA 573
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 61-122 4.38e-10

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 65.09  E-value: 4.38e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622   61 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLRGIFTRP 122
Cdd:COG5244      6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1774-2028 4.69e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 4.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1774 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1853
Cdd:TIGR02168  253 EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1854 LKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK-----------L 1922
Cdd:TIGR02168  333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeierlearlerL 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1923 EEERSVLNNQLLEMKKSLPSNTLRE-STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQS 2001
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          250       260
                   ....*....|....*....|....*..
gi 2024359622 2002 VVKTLESDKLKLEEKVKNLEQKLKAKS 2028
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLS 519
PTZ00121 PTZ00121
MAEBL; Provisional
 335-1159 5.74e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.16  E-value: 5.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  335 ARKISGTTALQEALKE-----KQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvRDGHDRHVLEMEAKMDQLRamvE 409
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDaeeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAK---K 1297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  410 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERdlALRVKEVAELRgrl 489
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEA--AEEKAEAAEKK--- 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  490 esskhiddvdtslsllqeiSSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTlsasnermgKENESLKTKLDHAN 569
Cdd:PTZ00121  1373 -------------------KEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL---------KKAAAAKKKADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  570 KEnsdvielwksklesaiASHQQAMEELKvsfnkgvgaqtaefaelKTQMEKVKLDYENEMSNLKLKQENEKSqhlKEIE 649
Cdd:PTZ00121  1425 KK----------------AEEKKKADEAK-----------------KKAEEAKKADEAKKKAEEAKKAEEAKK---KAEE 1468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  650 ALKAKLLEVTEEKEQTLENLKAKLESVEDQhlvemEDTLNKLQEAEIKVKELdvlqAKCNEQTKligslTQQIRASEEKl 729
Cdd:PTZ00121  1469 AKKADEAKKKAEEAKKADEAKKKAEEAKKK-----ADEAKKAAEAKKKADEA----KKAEEAKK-----ADEAKKAEEA- 1533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  730 ldlaalQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKnlSAVNQVKDSLEKEL 809
Cdd:PTZ00121  1534 ------KKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEE--ARIEEVMKLYEEEK 1605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  810 QLLKEKFTSAVDGAENAQRAMQE-----TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEN 884
Cdd:PTZ00121  1606 KMKAEEAKKAEEAKIKAEELKKAeeekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  885 D---IAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtlktHQEELKKMQ 961
Cdd:PTZ00121  1686 DekkAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD----EEEKKKIAH 1761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  962 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKK-NDELETQAEELKkqaEQAKS 1040
Cdd:PTZ00121  1762 LKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLViNDSKEMEDSAIK---EVADS 1838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1041 LSSVLASArKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILK 1120
Cdd:PTZ00121  1839 KNMQLEEA-DAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 2024359622 1121 QKEAAEAKSR--QESTEKVALISEKSKLLSEIETAQADLLK 1159
Cdd:PTZ00121  1918 KLDKDEYIKRdaEETREEIIKISKKDMCINDFSSKFCDYMK 1958
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1174-1667 9.04e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 9.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1174 LLQQLKELQANKDAVDVACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDS 1253
Cdd:COG1196    237 LEAELEELEAELEELEAELEELEAELAELE---AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1254 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTK 1333
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALR 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1334 DNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE---------ALFASEQRLLAEREELVNENKAVTEKLTKATADAV 1404
Cdd:COG1196    394 AAAELAAQLEELEEAEEALLERLERLEEELEELEEAlaeleeeeeEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1405 LAETAFTEKINELNlEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQEN 1484
Cdd:COG1196    474 LLEAALAELLEELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIV 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1485 TTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAkQVLSSSFNTCSSDIEILNRERTEL 1564
Cdd:COG1196    553 VEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD-LREADARYYVLGDTLLGRTLVAAR 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1565 QDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEE 1644
Cdd:COG1196    632 LEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                          490       500
                   ....*....|....*....|...
gi 2024359622 1645 VIKEKMILYKETEQLASKIEQLK 1667
Cdd:COG1196    712 AEEERLEEELEEEALEEQLEAER 734
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
621-1150 1.01e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.93  E-value: 1.01e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  621 KVKLDYENEMSNLK--LKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKV 698
Cdd:PRK03918   169 EVIKEIKRRIERLEkfIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKE-VKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  699 ----KELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQ-----------------KANSEGKLEIQKLSEQLQAAE 757
Cdd:PRK03918   248 esleGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKekaeeyiklsefyeeylDELREIEKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  758 KQIQNLETEKvggsSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKdSLEKELQLLKEKFT--------SAVDGAENAQRA 829
Cdd:PRK03918   328 ERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTgltpekleKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  830 MQETINKLNQKEEQFALMSSEL----EQLKS--------------------------NLTVMETKLKEREEREQQLTEAK 879
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELkkaiEELKKakgkcpvcgrelteehrkelleeytaELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  880 VKLENDIAEIMKSSgdssaQLMKMNDELRLKERQLEQIQLELTKANEKavqLQKNVEQTAQKAEqSQQETLKTHQEELKK 959
Cdd:PRK03918   483 RELEKVLKKESELI-----KLKELAEQLKELEEKLKKYNLEELEKKAE---EYEKLKEKLIKLK-GEIKSLKKELEKLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  960 MQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIK---GFKQNLLDAEEALKAAQKKNDELETQAEELKKQAE 1036
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKelePFYNEYLELKDAEKELEREEKELKKLEEELDKAFE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1037 QAKSLSSVLASARKEIELMS-----DKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEEL 1111
Cdd:PRK03918   634 ELAETEKRLEELRKELEELEkkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 2024359622 1112 NSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEI 1150
Cdd:PRK03918   714 EKLEKALERVEELREKVKKYKALLKERALSKVGEIASEI 752
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1280-1866 1.08e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.93  E-value: 1.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1280 RSLQSEKEMLLKSREELCVSLANTANenqaLKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREAS 1359
Cdd:PRK03918   165 KNLGEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1360 NSEKIHLLQ-EALFASEQRLLAEREELVNENKAVTEKLT---------KATADAVLAETAFTEKINELNLEKESVFSKSL 1429
Cdd:PRK03918   241 EELEKELESlEGSKRKLEEKIRELEERIEELKKEIEELEekvkelkelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1430 QFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENttlKYSIEALEEELKKKNLENQELI 1509
Cdd:PRK03918   321 EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELE---RLKKRLTGLTPEKLEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1510 ACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSsdieILNRERTELQDK--CQKLTGEVENMKENL-TVEK 1586
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCP----VCGRELTEEHRKelLEEYTAELKRIEKELkEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1587 KARILDKESFLLER-MELQNNIGFLEKEVEEMREKNKEFlteKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQ 1665
Cdd:PRK03918   474 KERKLRKELRELEKvLKKESELIKLKELAEQLKELEEKL---KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1666 LKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLhE 1745
Cdd:PRK03918   551 LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-D 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1746 KVVALLEQTDADF-SCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhQE 1824
Cdd:PRK03918   630 KAFEELAETEKRLeELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER-EK 708

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 2024359622 1825 KIETLASLENSRQTNEKLQNELDMLKqnNLKNEEELTKSKEL 1866
Cdd:PRK03918   709 AKKELEKLEKALERVEELREKVKKYK--ALLKERALSKVGEI 748
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
503-1079 2.55e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 2.55e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  503 SLLQEISSLQEKMAAAGKEHQrEMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSK 582
Cdd:PRK03918   211 EISSELPELREELEKLEKEVK-ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELK 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  583 LEsaiASHQQAMEELKVSFNKGvgaqtaefaelKTQMEKVKLDYENEMSNL--KLKQENEKSQHLKEIEALKAKL---LE 657
Cdd:PRK03918   290 EK---AEEYIKLSEFYEEYLDE-----------LREIEKRLSRLEEEINGIeeRIKELEEKEERLEELKKKLKELekrLE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  658 VTEEKEQTLENLKAKLESVE----DQHLVEMEDTLNKLQEAEIKVKELdvlQAKCNEQTKLIGSLTQQIrasEEKLLDLA 733
Cdd:PRK03918   356 ELEERHELYEEAKAKKEELErlkkRLTGLTPEKLEKELEELEKAKEEI---EEEISKITARIGELKKEI---KELKKAIE 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  734 ALQKANSEGKLEIQKLSEQlqaAEKQIQNLETEKVggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVkdsLEKELQLLK 813
Cdd:PRK03918   430 ELKKAKGKCPVCGRELTEE---HRKELLEEYTAEL------KRIEKELKEIEEKERKLRKELRELEKV---LKKESELIK 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  814 EKftSAVDGAENAQRAMQE-TINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKS 892
Cdd:PRK03918   498 LK--ELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAEL 575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  893 SGDSSAQLMKMNDELRLKERQLEQIQLELTKAnekavqlqknveQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQME 972
Cdd:PRK03918   576 LKELEELGFESVEELEERLKELEPFYNEYLEL------------KDAEKELEREEKELKKLEEELDKAFEELAETEKRLE 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  973 TSQNQYKDLQAKYEKETSEMItkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEI 1052
Cdd:PRK03918   644 ELRKELEELEKKYSEEEYEEL----------REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713

                          570       580
                   ....*....|....*....|....*..
gi 2024359622 1053 ELMSDKMRDLISEKETLAQERNTLKLE 1079
Cdd:PRK03918   714 EKLEKALERVEELREKVKKYKALLKER 740
PLN02939 PLN02939
transferase, transferring glycosyl groups
 642-972 2.62e-09

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 62.61  E-value: 2.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  642 SQHLKEIEALKAKLLEVTEEKEQ----TLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVLQakcneqtkligs 717
Cdd:PLN02939   102 MQRDEAIAAIDNEQQTNSKDGEQlsdfQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQ------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  718 ltQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLqaaEKQIQNLETEKVGGSSKVSNLTKELQgkeqkLLDLEkNLSa 797
Cdd:PLN02939   170 --GKINILEMRLSETDARIKLAAQEKIHVEILEEQL---EKLRNELLIRGATEGLCVHSLSKELD-----VLKEE-NML- 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  798 vnqvkdsLEKELQLLKEKFTSavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTE 877
Cdd:PLN02939   238 -------LKDDIQFLKAELIE-----------VAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWW 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  878 AKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQiqlELTKAN------EKAVQLQKNVEQTAQKAEQSQQET-- 949
Cdd:PLN02939   300 EKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEA---SLKEANvskfssYKVELLQQKLKLLEERLQASDHEIhs 376

                          330       340
                   ....*....|....*....|....
gi 2024359622  950 -LKTHQEELKKMQDQLTDMKKQME 972
Cdd:PLN02939   377 yIQLYQESIKEFQDTLSKLKEESK 400
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 497-1219 4.13e-09

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 62.05  E-value: 4.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  497 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKfESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI 576
Cdd:pfam05483   69 DFENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQK-ENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLI 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 E------LWKSKLESAIAS----------HQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENE 640
Cdd:pfam05483  148 KennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEM-----HFKLKEDHE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  641 KSQHLKEiealkaKLLEVTEEKEQTLENLKAKLESVEDQhlveMEDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQ 720
Cdd:pfam05483  223 KIQHLEE------EYKKEINDKEKQVSLLLIQITEKENK----MKDLTFLLEESRDKANQLE-------EKTKLQDENLK 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  721 QIRASEEKLLDLAALQKANSEGKLEIQK-LSEQLQAAEKQIQNLETEKvggSSKVSNLTKELQGKEQKLLDLEKNLSAVN 799
Cdd:pfam05483  286 ELIEKKDHLTKELEDIKMSLQRSMSTQKaLEEDLQIATKTICQLTEEK---EAQMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  800 QVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAK 879
Cdd:pfam05483  363 ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKE-------VELEELKKILAEDEKLLDEKKQFEKIAEELK 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  880 VKLENDIAEIM---KSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQET------L 950
Cdd:pfam05483  436 GKEQELIFLLQareKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEAsdmtleL 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  951 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHD---ADIKGFKQNLLDAEEALKAAQKKNDELETQ 1027
Cdd:pfam05483  516 KKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDevkCKLDKSEENARSIEYEVLKKEKQMKILENK 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1028 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETlaqERNTLKLEKESLLSQHLEM----ESKILLVQQDREE 1103
Cdd:pfam05483  596 CNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEI---KVNKLELELASAKQKFEEIidnyQKEIEDKKISEEK 672

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1104 LWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKS----KLLSEIETAQADLLKITQENDALRSSESTLLQQLK 1179
Cdd:pfam05483  673 LLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKhqydKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIK 752

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 2024359622 1180 -ELQANKDAVDVacqkhikEREELEHYQKLLEENDRVIKDK 1219
Cdd:pfam05483  753 aELLSLKKQLEI-------EKEEKEKLKMEAKENTAILKDK 786
PTZ00121 PTZ00121
MAEBL; Provisional
 868-1502 4.35e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.08  E-value: 4.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  868 REEREQQLTEAKVKLEND--IAEIMKSSGDSSAQLMKMNDELRLKE----RQLEQIQLELTKANEKAVQLQKNVEQTAQK 941
Cdd:PTZ00121  1194 RKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAeeakKAEEERNNEEIRKFEEARMAHFARRQAAIK 1273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  942 AEQSQQETLKTHQEELKKMQDqltdMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKN 1021
Cdd:PTZ00121  1274 AEEARKADELKKAEEKKKADE----AKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAK 1349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1022 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKEtlAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1101
Cdd:PTZ00121  1350 AEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE--AKKKAEEDKKKADELKKAAAAKKKADEAKKKA 1427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1102 EELwTKNEELnseNKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTllqQLKEL 1181
Cdd:PTZ00121  1428 EEK-KKADEA---KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA---KKKAD 1500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1182 QANKDAVDVACQKHIKEREELEHYQKLLEENDRviKDKDDVIQRLQSSYDDLARNQREL--LQEVSILTAERDSAQEKDL 1259
Cdd:PTZ00121  1501 EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA--KKADEAKKAEEKKKADELKKAEELkkAEEKKKAEEAKKAEEDKNM 1578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1260 DLKSTHIALKNEidcllqtnrslqsekemllKSREELCVSLANTANENQALKLRKDemqtelETEREKLEKMTKDNMDLK 1339
Cdd:PTZ00121  1579 ALRKAEEAKKAE-------------------EARIEEVMKLYEEEKKMKAEEAKKA------EEAKIKAEELKKAEEEKK 1633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1340 ASLSSLSNFLEEMKSSREASNSEKIHLLQealfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNL 1419
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1420 EKESVFSKSLQFEKHNEALLREKDELERKYSElldEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELK 1499
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEE---DKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD 1786


                   ...
gi 2024359622 1500 KKN 1502
Cdd:PTZ00121  1787 EED 1789
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
791-986 4.85e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 61.57  E-value: 4.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  791 LEKNLSAVNQVKDSLEKELQLLKEKftsaVDGAENAQRAMQETiNKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 870
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKE----LEEAEAALEEFRQK-NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  871 REQQLTEAKVKLENDIAEIMkssgdSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVE-------------- 936
Cdd:COG3206    241 RLAALRAQLGSGPDALPELL-----QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAalraqlqqeaqril 315

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  937 -------QTAQKAEQSQQETLKTHQEELKKM---QDQLTDMKKQMETSQNQYKDLQAKYE 986
Cdd:COG3206    316 asleaelEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLE 375
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1554-2075 6.04e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 61.62  E-value: 6.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1554 IEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMrEKNKEFLTEKELLVQ 1633
Cdd:PRK03918   171 IKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1634 EKEKSETKLEEVIK--EKMI--LYKETEQLASKIEQLKS------DFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEK 1703
Cdd:PRK03918   249 SLEGSKRKLEEKIRelEERIeeLKKEIEELEEKVKELKElkekaeEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1704 EkmelVQENESLHAEWKSLVIINEEILKEKEKLsKEYYKLHEKVVALLEQTD---ADFSCR--------LLVSEGKHELL 1772
Cdd:PRK03918   329 R----IKELEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELErlkKRLTGLtpeklekeLEELEKAKEEI 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1773 LEEMSNLALKLREIERLQAQ--TFMQKFEADKRA----------EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1840
Cdd:PRK03918   404 EEEISKITARIGELKKEIKElkKAIEELKKAKGKcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELR 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1841 KLQNELdmlkqnnlKNEEELTKSKELL----NLENK-------KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEEL 1909
Cdd:PRK03918   484 ELEKVL--------KKESELIKLKELAeqlkELEEKlkkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1910 GRSRDEVTSHQKLEEERSVLNNQLLEMK-KSLPSNTLRESTLK---------KEIDEERASLQKSISDTSALITQKDEEL 1979
Cdd:PRK03918   556 KKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEpfyneylelKDAEKELEREEKELKKLEEELDKAFEEL 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1980 EKLRNEITVLRGENASAKTLQSV--VKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLlqdESAEDKQQE 2057
Cdd:PRK03918   636 AETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL---EEREKAKKE 712

                          570
                   ....*....|....*...
gi 2024359622 2058 IDFLNSVIVDLQRRNEEL 2075
Cdd:PRK03918   713 LEKLEKALERVEELREKV 730
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 608-1581 6.18e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 61.60  E-value: 6.18e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  608 QTAEFAELKTQMEKVKLDY-----ENEMSNLKLKQENEKSQHLKEI----EALKAKLLEVTEEKEQTLENLKAKLESVED 678
Cdd:TIGR00606  180 SATRYIKALETLRQVRQTQgqkvqEHQMELKYLKQYKEKACEIRDQitskEAQLESSREIVKSYENELDPLKNRLKEIEH 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  679 Q--HLVEMEDTLNKLQEAEIKVKeldvlqakcNEQTKLIGSLTQQIRASEEKLLDLAALQKAnsegklEIQKLSEQLQAA 756
Cdd:TIGR00606  260 NlsKIMKLDNEIKALKSRKKQME---------KDNSELELKMEKVFQGTDEQLNDLYHNHQR------TVREKERELVDC 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  757 EKQIQNLETEKVGGSSKVSNLTKElQGKEQklldleknLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 836
Cdd:TIGR00606  325 QRELEKLNKERRLLNQEKTELLVE-QGRLQ--------LQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNF 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  837 LNQKEEQFALMSSELEQLKSNLTvmetklkereEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:TIGR00606  396 HTLVIERQEDEAKTAAQLCADLQ----------SKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQ 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 IQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLtDMKKQMETSQNQYKDLQAKYEKETsEMITKH 996
Cdd:TIGR00606  466 LEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADL-DRKLRKLDQEMEQLNHHTTTRTQM-EMLTKD 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  997 DADikgfkqnllDAEEALKAAQKKNDELETQAEELKKQaeqaKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1076
Cdd:TIGR00606  544 KMD---------KDEQIRKIKSRHSDELTSLLGYFPNK----KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHI 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1077 KLEKESLLSQHLEMESKILlvqqdrEELWTKNEELNSENKKilkqkeaaeaKSRQESTEKVALISEKSKLLSEIETaqad 1156
Cdd:TIGR00606  611 NNELESKEEQLSSYEDKLF------DVCGSQDEESDLERLK----------EEIEKSSKQRAMLAGATAVYSQFIT---- 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1157 llKITQENDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1236
Cdd:TIGR00606  671 --QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPE 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1237 QRELLQEVSILTAERDSAQEKDLDLKSThIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLAnTANENQALKLRKDE 1316
Cdd:TIGR00606  749 LRNKLQKVNRDIQRLKNDIEEQETLLGT-IMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQA-AKLQGSDLDRTVQQ 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1317 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAlfaseQRLLAEREELVNENKAVTEkL 1396
Cdd:TIGR00606  827 VNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNL-----QRRQQFEEQLVELSTEVQS-L 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1397 TKATADAVLAETAFTEKINELNLEKESVFSKSlqfEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsa 1476
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSK---ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDY------ 971

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1477 krlLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSdllkEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEI 1556
Cdd:TIGR00606  972 ---LKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDID----TQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEM 1044

                          970       980
                   ....*....|....*....|....*
gi 2024359622 1557 LNRERTELQDKCQKLTGEVENMKEN 1581
Cdd:TIGR00606 1045 GQMQVLQMKQEHQKLEENIDLIKRN 1069
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1127-1924 7.27e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 61.24  E-value: 7.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1127 AKSRQESTEKVALISEKSkllSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDvACQKHIKEREELEHYQ 1206
Cdd:TIGR02169  152 PVERRKIIDEIAGVAEFD---RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYE 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1207 KL--LEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKS-THIALKNEIDCLLQTNRSLQ 1283
Cdd:TIGR02169  228 LLkeKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLE 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1284 SEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEM----KSSREAS 1359
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVdkefAETRDEL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1360 NSEKIHLlqEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAEtaftEKINELNLEKESVFSKSLQFEKHNEALL 1439
Cdd:TIGR02169  388 KDYREKL--EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1440 REKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKK--------KNLENQELIAC 1511
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqlGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1512 RSDLS------------------DLLKEAQDARRTL--------ENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQ 1565
Cdd:TIGR02169  542 EVAAGnrlnnvvveddavakeaiELLKRRKAGRATFlplnkmrdERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFG 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1566 DkcqklTGEVENMKENLTVEKKARILDKESFLLER-----------MELQNNIGFLEKEVEEMREKNKEFLTEKELLVQE 1634
Cdd:TIGR02169  622 D-----TLVVEDIEAARRLMGKYRMVTLEGELFEKsgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1635 KEK--------------SETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhscvsvMLDELQHKYEV 1700
Cdd:TIGR02169  697 LRRienrldelsqelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS-------ELKELEARIEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1701 TEKEKMELVQENESLHAEwkslviINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLvsegKHELLLEEMSNLA 1780
Cdd:TIGR02169  770 LEEDLHKLEEALNDLEAR------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTL----EKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1781 LKLREIErlqaqtfmqkfeaDKRAEevlqtmekVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEEL 1860
Cdd:TIGR02169  840 EQRIDLK-------------EQIKS--------IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622 1861 TKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEE 1924
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR 962
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1322-1963 7.48e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 7.48e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1322 ETEReKLEKmTKDNMD--------LKASLSSLSnfleemkssREASNSEKIHLLQEALFASEQRL-LAEREELVNENKAV 1392
Cdd:COG1196    176 EAER-KLEA-TEENLErledilgeLERQLEPLE---------RQAEKAERYRELKEELKELEAELlLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1393 TEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQEl 1472
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1473 dfsAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSS 1552
Cdd:COG1196    324 ---ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1553 DIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLV 1632
Cdd:COG1196    401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1633 QEKEKSETKLEEvikekmilyKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQEN 1712
Cdd:COG1196    481 ELLEELAEAAAR---------LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1713 eslhaewkslVIINEEILKEKEKLSKEYyKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ 1792
Cdd:COG1196    552 ----------VVEDDEVAAAAIEYLKAA-KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1793 TFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdmlkqnnLKNEEELTKSKELLNLENK 1872
Cdd:COG1196    621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL-------LEAEAELEELAERLAEEEL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1873 KVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtsHQKLEEERSVLNNQLLEMKKSLPSntlrESTLKK 1952
Cdd:COG1196    694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREEL--LEELLEEEELLEEEALEELPEPPD----LEELER 767

                          650
                   ....*....|.
gi 2024359622 1953 EIDEERASLQK 1963
Cdd:COG1196    768 ELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 904-1136 8.27e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 60.16  E-value: 8.27e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  904 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQE------TLKTHQEELKKMQDQLTDMKKQMETSQNQ 977
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRiaalarRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  978 YKDLQAKYEKETSEMITKHDADIKGF---KQNLLDAEEALKAAQKKNDELETQAEELKKQAEQakslssvLASARKEIEL 1054
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE-------LAALRAELEA 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1055 MSDKMRDLISEKETLAQERNTLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQEST 1134
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGF 248


                   ..
gi 2024359622 1135 EK 1136
Cdd:COG4942    249 AA 250
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
942-1187 8.95e-09

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 60.80  E-value: 8.95e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  942 AEQSQQETLKTHQEELKK----MQDQLTDMKKQMETSQNQYKDLQAKYeketsemitkhdadikgfkqNLLDAEEALKAA 1017
Cdd:COG3206    158 AEAYLEQNLELRREEARKalefLEEQLPELRKELEEAEAALEEFRQKN--------------------GLVDLSEEAKLL 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1018 QKKNDELETQAEELKKQAEQAKSLssvLASARKEIELMSDKMRDLISEKE--TLAQERNTLKLEKESLLSQHLEMESKIL 1095
Cdd:COG3206    218 LQQLSELESQLAEARAELAEAEAR---LAALRAQLGSGPDALPELLQSPViqQLRAQLAELEAELAELSARYTPNHPDVI 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1096 LVQQDREELwtkNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL 1175
Cdd:COG3206    295 ALRAQIAAL---RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371

                          250
                   ....*....|..
gi 2024359622 1176 QQLKELQANKDA 1187
Cdd:COG3206    372 QRLEEARLAEAL 383
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 795-1049 1.07e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.78  E-value: 1.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  795 LSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQ 874
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  875 LTEAKVKLENDIAEImkssgdssaqlmkmndeLRLKERQLEQIQLELTKANEKAVQLQKNVE--QTAQKAEQSQQETLKT 952
Cdd:COG4942     95 LRAELEAQKEELAEL-----------------LRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  953 HQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1032
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233

                          250
                   ....*....|....*..
gi 2024359622 1033 KQAEQAKSLSSVLASAR 1049
Cdd:COG4942    234 AEAAAAAERTPAAGFAA 250
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 329-815 1.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  329 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrhvlEMEAKMDQLRAMV 408
Cdd:COG1196    292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE-----------EAEEELEEAEAEL 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  409 EAADREKVELLNQLEEEKRKVEDLQFRVEEEsitKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGR 488
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLEA---LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  489 LESSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDH 567
Cdd:COG1196    438 EEEEEALEEAAEEEAeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLA 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  568 ANKENS---DVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAeLKTQMEKVKLDYENEMSNLKLKQENEKSQH 644
Cdd:COG1196    518 GLRGLAgavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL-KAAKAGRATFLPLDKIRARAALAAALARGA 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  645 LKEIEALKAKLLEVTEEKEQTLENlkAKLESVEDQHLVEMEDTLNKLQEAEIKVKELD----------VLQAKCNEQTKL 714
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGD--TLLGRTLVAARLEAALRRAVTLAGRLREVTLEgeggsaggslTGGSRRELLAAL 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  715 IGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKN 794
Cdd:COG1196    675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          490       500
                   ....*....|....*....|.
gi 2024359622  795 LSAVNQVKDSLEKELQLLKEK 815
Cdd:COG1196    755 ELPEPPDLEELERELERLERE 775
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
775-1338 1.23e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.23e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  775 SNLTKELQGKEQKllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQramqETINKLNQKEEQFALMSSELEQL 854
Cdd:PRK02224   190 DQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEAD----EVLEEHEERREELETLEAEIEDL 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  855 KSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKN 934
Cdd:PRK02224   264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  935 VEQTAQKAEQSQQETlKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEAL 1014
Cdd:PRK02224   344 AESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIE-ELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1015 KAAQKKNDELETQAEELKKQAEQAKSL----------SSVLASARKE-IELMSDKMRDLISEKETLAQERNTLKlEKESL 1083
Cdd:PRK02224   422 DELREREAELEATLRTARERVEEAEALleagkcpecgQPVEGSPHVEtIEEDRERVEELEAELEDLEEEVEEVE-ERLER 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1084 LSQHLEMESKILLVQQDREELwtknEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQE 1163
Cdd:PRK02224   501 AEDLVEAEDRIERLEERREDL----EELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1164 NDALRSSESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDD----LARNQRE 1239
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEarieEAREDKE 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1240 LLQE-VSILTAERDSAQEKDLDLKSTHIALKNEIDCLlqtnRSLQSEKEMLLKSREELcVSLANTANENQAL--KLRKDE 1316
Cdd:PRK02224   657 RAEEyLEQVEEKLDELREERDDLQAEIGAVENELEEL----EELRERREALENRVEAL-EALYDEAEELESMygDLRAEL 731

                          570       580
                   ....*....|....*....|..
gi 2024359622 1317 MQTELETerekLEKMTKDNMDL 1338
Cdd:PRK02224   732 RQRNVET----LERMLNETFDL 749
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 530-1181 1.29e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 60.37  E-value: 1.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  530 KEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELwkSKLESAIASHQQAMEELKVSfnkgvgAQT 609
Cdd:TIGR00618  221 KQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARI--EELRAQEAVLEETQERINRA------RKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  610 AEFAELKTQMEKVKLDYENEMSNLKlKQENEKSQHLKEIEALKAKLLEVtEEKEQTLENLKAKLESVEDQHLV------- 682
Cdd:TIGR00618  293 APLAAHIKAVTQIEQQAQRIHTELQ-SKMRSRAKLLMKRAAHVKQQSSI-EEQRRLLQTLHSQEIHIRDAHEVatsirei 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  683 ---EMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQ 759
Cdd:TIGR00618  371 scqQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  760 IQNLETEK---VGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT------SAVDGAENAQRAM 830
Cdd:TIGR00618  451 AQCEKLEKihlQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIhpnparQDIDNPGPLTRRM 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  831 QETINKLNQKEEQFALMSSELEQLKSNLTvmetKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND-ELRL 909
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDVYHQLTSERKQRA----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEkLSEA 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  910 KERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDL-QAKYEKE 988
Cdd:TIGR00618  607 EDMLACEQHALLRKLQPEQDLQDVRLHL-QQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASrQLALQKM 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  989 TSEmitkhdadikgfKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQaksLSSVLASARKEIELMSDKMRDLISEKE- 1067
Cdd:TIGR00618  686 QSE------------KEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE---IENASSSLGSDLAAREDALNQSLKELMh 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1068 ---------TLAQERNTLKLEKESLLSQHL-----EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQES 1133
Cdd:TIGR00618  751 qartvlkarTEAHFNNNEEVTAALQTGAELshlaaEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEE 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359622 1134 TEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1181
Cdd:TIGR00618  831 EQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1779-2057 1.35e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1779 LALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEE 1858
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1859 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKK 1938
Cdd:COG1196    296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEEL---EEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1939 SLPSNTLRESTLKKEIDE---ERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEE 2015
Cdd:COG1196    373 ELAEAEEELEELAEELLEalrAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359622 2016 KVKNLEQKLKAKSEQPLTVTsPSGDIAANLLQDESAEDKQQE 2057
Cdd:COG1196    453 ELEEEEEALLELLAELLEEA-ALLEAALAELLEELAEAAARL 493
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 470-1185 1.64e-08

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 59.84  E-value: 1.64e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  470 ELERDLALRVKEVAELRGRLESSKHIDDVDTSLSL----LQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIK 545
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQEENQHLQLtiqaLQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFR 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  546 TLSASNERMGKENESLKTKLDHANKEnsdvIELWKSKLESAIASHQQAMEELK--------VSFNKGVGAQTAEfAELKT 617
Cdd:pfam10174  120 RLQSEHERQAKELFLLRKTLEEMELR----IETQKQTLGARDESIKKLLEMLQskglpkksGEEDWERTRRIAE-AEMQL 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  618 QMEKVKLDyENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIK 697
Cdd:pfam10174  195 GHLEVLLD-QKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEE 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  698 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLL----DLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggssk 773
Cdd:pfam10174  274 IKQMEVYKSHSKFMKNKIDQLKQELSKKESELLalqtKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTE------- 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  774 VSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 853
Cdd:pfam10174  347 VDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKS 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  854 LKSN-------LTVMETKLKEREE-----REQQLTEAKVKLEnDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLEL 921
Cdd:pfam10174  427 LQTDssntdtaLTTLEEALSEKERiierlKEQREREDRERLE-ELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHA 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  922 T-------KANEKAVQLQKNVEQTAQKAEQSQQETLKTHQ-EELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 992
Cdd:pfam10174  506 SslassglKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNaEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLl 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  993 -ITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSsVLASARKEIELMSDKMRDLISEKETLAQ 1071
Cdd:pfam10174  586 gILREVENEKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQ-LLEEARRREDNLADNSQQLQLEELMGAL 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1072 ERNTLKLEkesllsqhlEMESKILLVQQDREELWTKNEELNSENKKILKqkEAAEAKsrQESTekVALISEKSKLLSEIE 1151
Cdd:pfam10174  665 EKTRQELD---------ATKARLSSTQQSLAEKDGHLTNLRAERRKQLE--EILEMK--QEAL--LAAISEKDANIALLE 729

                          730       740       750
                   ....*....|....*....|....*....|....
gi 2024359622 1152 TAQADLLKITQENDALRSSESTLLQQLKELQANK 1185
Cdd:pfam10174  730 LSSSKKKKTQEEVMALKREKDRLVHQLKQQTQNR 763
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 396-1398 2.30e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.80  E-value: 2.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  396 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRqisedpenvatVSEKSRIMELERDL 475
Cdd:pfam01576   72 ELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEK-----------VTTEAKIKKLEEDI 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  476 ALrvkeVAELRGRLESSKhiddvdtslSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESS----EEALRKEiktlsasn 551
Cdd:pfam01576  141 LL----LEDQNSKLSKER---------KLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMisdlEERLKKE-------- 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  552 ERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFA------ELKTQMEKVKLD 625
Cdd:pfam01576  200 EKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNalkkirELEAQISELQED 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  626 YENEMSnLKLKQENEKSQHLKEIEALKAKLL----------EVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAe 695
Cdd:pfam01576  280 LESERA-ARNKAEKQRRDLGEELEALKTELEdtldttaaqqELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQA- 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  696 ikvkeLDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA----LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 771
Cdd:pfam01576  358 -----LEELTEQLEQAKRNKANLEKAKQALESENAELQAelrtLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELA 432

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  772 SKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTsavdgaenaqramQETINKLNqkeeqfalMSSEL 851
Cdd:pfam01576  433 EKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQ-------------EETRQKLN--------LSTRL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  852 EQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQL 931
Cdd:pfam01576  492 RQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKL 571

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  932 QKNVEQTAQKAEQS--QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDAdikgFKQNLLD 1009
Cdd:pfam01576  572 EKTKNRLQQELDDLlvDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS----LARALEE 647

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1010 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEkesllsqhLE 1089
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLR--------LE 719

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1090 MESKILLVQQDReELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLlkitqenDALRS 1169
Cdd:pfam01576  720 VNMQALKAQFER-DLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQI-------DAANK 791

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1170 SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleENDRVIKDKDDVIQRLQssyDDLARNQRELLQevsiLTA 1249
Cdd:pfam01576  792 GREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSK---ESEKKLKNLEAELLQLQ---EDLAASERARRQ----AQQ 861

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1250 ERDSAQEKDLDLKSTHIALKNEidcllqtNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLE 1329
Cdd:pfam01576  862 ERDELADEIASGASGKSALQDE-------KRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQ 934

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359622 1330 KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTK 1398
Cdd:pfam01576  935 KSESARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVRRTEKK 1003
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 341-1209 2.44e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.42  E-value: 2.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  341 TTALQEALKEKQQHIEQLLAERDLERA-------EVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVE--AA 411
Cdd:pfam01576   91 SQQLQNEKKKMQQHIQDLEEQLDEEEAarqklqlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSnlAE 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  412 DREKVELLNQLEEEKRKV-EDLQFRVEEESITKGDLERKRQISEdpenvatvsekSRIMELERDLALRVKEVAELRGRLe 490
Cdd:pfam01576  171 EEEKAKSLSKLKNKHEAMiSDLEERLKKEEKGRQELEKAKRKLE-----------GESTDLQEQIAELQAQIAELRAQL- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  491 sSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTlsasNERMGKENESLKTKLDHANK 570
Cdd:pfam01576  239 -AKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQ----RRDLGEELEALKTELEDTLD 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  571 ENSDVIELwKSKLESAIASHQQAMEELKVSFNKGVG----AQTAEFAELKTQMEKVKldyENEMSNLKLKQ--ENEKSQH 644
Cdd:pfam01576  314 TTAAQQEL-RSKREQEVTELKKALEEETRSHEAQLQemrqKHTQALEELTEQLEQAK---RNKANLEKAKQalESENAEL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  645 LKEIEALKAKLLEVTEEK---EQTLENLKAKLESVEDQHlVEMEDTLNKLQ-EAEIKVKELDVLQAKCNEQTKLIGSLTQ 720
Cdd:pfam01576  390 QAELRTLQQAKQDSEHKRkklEGQLQELQARLSESERQR-AELAEKLSKLQsELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  721 QIRASEEKLldlaalqkansegkleiQKLSEQLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQ 800
Cdd:pfam01576  469 QLQDTQELL-----------------QEETRQKLNLSTRLRQLEDER-------NSLQEQLEEEEEAKRNVERQLSTLQA 524

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  801 VKDSLEKELqllkEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKV 880
Cdd:pfam01576  525 QLSDMKKKL----EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLE 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  881 KLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTaQKAEQSQQETLKTHQEELKK- 959
Cdd:pfam01576  601 KKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELERT-NKQLRAEMEDLVSSKDDVGKn 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  960 ----------MQDQLTDMKKQMETSQNQYK---DLQAKYEKETSEMITKHDADIKGFKQNlldAEEALKAAQKKNDELET 1026
Cdd:pfam01576  680 vhelerskraLEQQVEEMKTQLEELEDELQateDAKLRLEVNMQALKAQFERDLQARDEQ---GEEKRRQLVKQVRELEA 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1027 QAEELKKQAEQA-----------KSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKIL 1095
Cdd:pfam01576  757 ELEDERKQRAQAvaakkkleldlKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLK 836

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1096 LVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL 1175
Cdd:pfam01576  837 NLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKST 916

                          890       900       910
                   ....*....|....*....|....*....|....
gi 2024359622 1176 QQLKELQANKDAVDVACQKHIKEREELEHYQKLL 1209
Cdd:pfam01576  917 LQVEQLTTELAAERSTSQKSESARQQLERQNKEL 950
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1083-1926 2.49e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.60  E-value: 2.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1083 LLSQHLEMESKILLVQQDREElwtkNEELNSENKKILKQKEAAEAKS----RQESTEKVALISEKSKLLSEIETAQADLL 1158
Cdd:pfam02463  125 LESQGISPEAYNFLVQGGKIE----IIAMMKPERRLEIEEEAAGSRLkrkkKEALKKLIEETENLAELIIDLEELKLQEL 200

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1159 KIT-QENDALRSSESTLLQQLKELQANKDAVDVACQKHIKE-REELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARN 1236
Cdd:pfam02463  201 KLKeQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLlQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKE 280

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1237 QRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDE 1316
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1317 MQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKS--SREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTE 1394
Cdd:pfam02463  361 LEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIE 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1395 KLTKATADAVLAETAFTEKINELNLEKESVF------SKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR 1468
Cdd:pfam02463  441 LKQGKLTEEKEELEKQELKLLKDELELKKSEdllketQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGV 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1469 EQELDFSAKRLLVQENTTLKYS---IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1545
Cdd:pfam02463  521 GGRIISAHGRLGDLGVAVENYKvaiSTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEID 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1546 SFNTCSSDIEILNRERTELQDKCQKlTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1625
Cdd:pfam02463  601 PILNLAQLDKATLEADEDDKRAKVV-EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1626 TEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1705
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1706 MELVQ------------ENESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRL--LVSEGKHEL 1771
Cdd:pfam02463  760 EEKEEekselslkekelAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkiKEEELEELA 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1772 LLEEMSNLALKLREIErlqaqTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQ 1851
Cdd:pfam02463  840 LELKEEQKLEKLAEEE-----LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEE 914

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1852 NNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEER 1926
Cdd:pfam02463  915 KENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEER 989
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1306-1884 4.73e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 4.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1306 ENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNsEKIHLLQEAlfasEQRLLAEREEL 1385
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE-LELEEAQAE----EYELLAELARL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1386 VNENKAVTEKLTkatadavlaetAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSD 1465
Cdd:COG1196    301 EQDIARLEERRR-----------ELEERLEELEEELA-------ELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1466 MKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSS 1545
Cdd:COG1196    363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1546 SFNTCSSDIEILNRERTELQDKcQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFL 1625
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLEL-LAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1626 TEKEL--LVQEKEKSETKLEEVIKEKM--ILYKETEQLASKIEQLKSD------FTSLSVSKAE--LEDVHSCVSVMLDE 1693
Cdd:COG1196    522 LAGAVavLIGVEAAYEAALEAALAAALqnIVVEDDEVAAAAIEYLKAAkagratFLPLDKIRARaaLAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1694 LQHKYEVTEKEKMELVQENESLHAEWKSLVIINEEILKEKEKlskeyyklHEKVVALLEQTDADFScRLLVSEGKHELLL 1773
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLA--------GRLREVTLEGEGGSAG-GSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1774 EEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNN 1853
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580       590
                   ....*....|....*....|....*....|.
gi 2024359622 1854 LKNEEELTKSKELlnleNKKVEELKKEFEAL 1884
Cdd:COG1196    753 LEELPEPPDLEEL----ERELERLEREIEAL 779
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
828-1249 5.51e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 58.24  E-value: 5.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  828 RAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEIMKSSGDSSAQLMKMNDEL 907
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP--LYQELEALEAELAELPERLEEL 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  908 RLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEK 987
Cdd:COG4717    152 EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQ 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  988 ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVL--------ASARKEIELMSDKM 1059
Cdd:COG4717    232 LENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLflllarekASLGKEAEELQALP 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1060 RDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK--EAAEAKSRQESTEKV 1137
Cdd:COG4717    312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllAEAGVEDEEELRAAL 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1138 ALISEKSKLLSEIETAQADLLKITQENDALRS--SESTLLQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRv 1215
Cdd:COG4717    392 EQAEEYQELKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE- 470

                          410       420       430
                   ....*....|....*....|....*....|....
gi 2024359622 1216 ikdkddvIQRLQSSYDDLARNQRELLQEVSILTA 1249
Cdd:COG4717    471 -------LAELLQELEELKAELRELAEEWAALKL 497
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 657-1594 6.08e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 58.26  E-value: 6.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  657 EVTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKE-LDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA- 734
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESE-LKELEKKHQQLCEEKNALQEqLQAETELCAEAEEMRARLAARKQELEEILHELESr 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  735 ----------LQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLtkelqgkEQKLLDLEKNLSAVNQVKDS 804
Cdd:pfam01576   84 leeeeersqqLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL-------EEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  805 LEKELQLLKEKFTSAVDGAENaqramqetINKLNQKEEqfalmsseleqlkSNLTVMETKLKEREEREQQLTEAKVKLEN 884
Cdd:pfam01576  157 LEERISEFTSNLAEEEEKAKS--------LSKLKNKHE-------------AMISDLEERLKKEEKGRQELEKAKRKLEG 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  885 DIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV-EQTAQKAEqsQQETLKTHQEELKKMQDQ 963
Cdd:pfam01576  216 ESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIrELEAQISE--LQEDLESERAARNKAEKQ 293

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  964 LTDMKKQMETSQNQYKDLQAKYEKEtSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQA-EELKKQAEQAKSLS 1042
Cdd:pfam01576  294 RRDLGEELEALKTELEDTLDTTAAQ-QELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1043 SVLASARKEIElmsDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSE-------- 1114
Cdd:pfam01576  373 ANLEKAKQALE---SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSElesvssll 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1115 ----NKKILKQKEAAEAKSR---------QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL--- 1178
Cdd:pfam01576  450 neaeGKNIKLSKDVSSLESQlqdtqellqEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLsdm 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1179 -KELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL---------- 1247
Cdd:pfam01576  530 kKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLekkqkkfdqm 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1248 -----------TAERDSAQEKDLDLKSTHIALKNEIDCLL-------QTNRSLQSEKEMLLKSREELCVSLANTANENQA 1309
Cdd:pfam01576  610 laeekaisaryAEERDRAEAEAREKETRALSLARALEEALeakeeleRTNKQLRAEMEDLVSSKDDVGKNVHELERSKRA 689

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1310 LKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEALFASEQRLLAER------- 1382
Cdd:pfam01576  690 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERkqraqav 769

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1383 ------EELVNENKAVTEKLTKATADAV-------LAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKY 1449
Cdd:pfam01576  770 aakkklELDLKELEAQIDAANKGREEAVkqlkklqAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDL 849

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1450 SELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLeNQELiacrsdLSDLLKEAQDARRTL 1529
Cdd:pfam01576  850 AASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS-NTEL------LNDRLRKSTLQVEQL 922

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1530 ENELAAVSHAKQVLSSSFNTcssdieiLNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1594
Cdd:pfam01576  923 TTELAAERSTSQKSESARQQ-------LERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQLE 980
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2150-2166 7.71e-08

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.77  E-value: 7.71e-08
                           10
                   ....*....|....*..
gi 2024359622 2150 RPYCDTCEMFGHWTADC 2166
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PTZ00121 PTZ00121
MAEBL; Provisional
 1349-2022 8.25e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 8.25e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1349 LEEMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAfTEKINELNLEKESVFSKS 1428
Cdd:PTZ00121  1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADELKKAEEKKKA 1292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1429 LQFEKHNEAL----LREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEALEEELKKKNLE 1504
Cdd:PTZ00121  1293 DEAKKAEEKKkadeAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKK 1372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1505 NQEliaCRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTV 1584
Cdd:PTZ00121  1373 KEE---AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA 1449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1585 EKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-----KNKEFLTEKELLVQEKEKSETKLEEVIKEKMilYKETEQL 1659
Cdd:PTZ00121  1450 KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1660 ASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK----MELVQENESLHAEWKSLVIINEEILKEKEK 1735
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEedknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1736 LSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVT 1815
Cdd:PTZ00121  1608 KAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1816 KEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQL 1895
Cdd:PTZ00121  1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEE 1767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1896 AALQEENVKLAEELGRSRDEVTSHQKLEEERSVlnNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQK 1975
Cdd:PTZ00121  1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKI--KDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEE 1845

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359622 1976 DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQ 2022
Cdd:PTZ00121  1846 ADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEK 1892
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 790-2022 9.52e-08

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 57.75  E-value: 9.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKdsleKELQLLKEkFTSAVDGAENAQRAMQETINKLNQKEEQF--ALMSSELEQ-LKSNLTVM----E 862
Cdd:TIGR01612  484 DIDENSKQDNTVK----LILMRMKD-FKDIIDFMELYKPDEVPSKNIIGFDIDQNikAKLYKEIEAgLKESYELAknwkK 558

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  863 TKLKEREEREQQlTEAKVKLENDIAEIMKssgdssaQLMKMNDEL----RLKERQLEQIQlELTKANE---KAVQLQKNV 935
Cdd:TIGR01612  559 LIHEIKKELEEE-NEDSIHLEKEIKDLFD-------KYLEIDDEIiyinKLKLELKEKIK-NISDKNEyikKAIDLKKII 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  936 EQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKqmETSQNQYKDLQAKYeKETSEMITKHDADIKGFKQNLLDAEEALK 1015
Cdd:TIGR01612  630 ENNNAYIDELAKISPYQVPEHLKNKDKIYSTIKS--ELSKIYEDDIDALY-NELSSIVKENAIDNTEDKAKLDDLKSKID 706

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1016 AAQKKNDELETQAEELkkqaeqakSLSSvlasarkeIELMSDKMRDLISE--KETLAQERNTLKLEKESLLSQHLEMESK 1093
Cdd:TIGR01612  707 KEYDKIQNMETATVEL--------HLSN--------IENKKNELLDIIVEikKHIHGEINKDLNKILEDFKNKEKELSNK 770

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1094 IllvqqdrEELWTKNEELNSENKKILKQKEAAEAKSRQEST--EKVALISEKSK-LLSEIETAQADLLKITQEndalrss 1170
Cdd:TIGR01612  771 I-------NDYAKEKDELNKYKSKISEIKNHYNDQINIDNIkdEDAKQNYDKSKeYIKTISIKEDEIFKIINE------- 836

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1171 estlLQQLKELQANKDAVDVACQKHIKEREELEHYQKlleeNDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSiltae 1250
Cdd:TIGR01612  837 ----MKFMKDDFLNKVDKFINFENNCKEKIDSEHEQF----AELTNKIKAEISDDKLNDYEKKFNDSKSLINEIN----- 903

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1251 rdSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEK 1330
Cdd:TIGR01612  904 --KSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDK 981

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1331 MTKDnmdlkASLSSLsnfleemkssrEASNSEKIHL---LQEALFASEQRLL----AEREELVNEnkaVTEKLTKATADA 1403
Cdd:TIGR01612  982 AFKD-----ASLNDY-----------EAKNNELIKYfndLKANLGKNKENMLyhqfDEKEKATND---IEQKIEDANKNI 1042

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1404 VLAETAFTEKINELNLEKESVFSKSLqfEKHNEALLREKDELERKYSELlDEKKSLENaFSDMKREQELDFS-----AKR 1478
Cdd:TIGR01612 1043 PNIEIAIHTSIYNIIDEIEKEIGKNI--ELLNKEILEEAEINITNFNEI-KEKLKHYN-FDDFGKEENIKYAdeinkIKD 1118

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1479 LLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEA------QDARRTLENELAAVSHAKQVLSSsFNTCSS 1552
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKAisnddpEEIEKKIENIVTKIDKKKNIYDE-IKKLLN 1197

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1553 DIEILNRERTELQdkcqkltgEVENMkeNLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMRE-KNKEFLTEKELL 1631
Cdd:TIGR01612 1198 EIAEIEKDKTSLE--------EVKGI--NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEiKEKSPEIENEMG 1267

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1632 VQEKEKSETKLEEV----IKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDV--------------HSCVSVMLDE 1693
Cdd:TIGR01612 1268 IEMDIKAEMETFNIshddDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIkkelqknlldaqkhNSDINLYLNE 1347

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1694 LQHKYEVTEKEKM--------ELVQENESLHAEWKSLVIINEEILKE-KEKLSKEYYKlhEKVVALLEQTDADfSCRLLV 1764
Cdd:TIGR01612 1348 IANIYNILKLNKIkkiidevkEYTKEIEENNKNIKDELDKSEKLIKKiKDDINLEECK--SKIESTLDDKDID-ECIKKI 1424

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1765 SEGKHELLLEEMSNLAL--KLREIERLQAQTFMQKFEADKRAEEVLQTmekvtkEKDAIHQEKIETLASLENSRQTNEKL 1842
Cdd:TIGR01612 1425 KELKNHILSEESNIDTYfkNADENNENVLLLFKNIEMADNKSQHILKI------KKDNATNDHDFNINELKEHIDKSKGC 1498

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1843 QNELDmlkqnnlKNEEELTKSKELLNLENKKVEELKKEFEALKL------AAAQKSQQLAALQEENVKLAEELGRSRDEV 1916
Cdd:TIGR01612 1499 KDEAD-------KNAKAIEKNKELFEQYKKDVTELLNKYSALAIknkfakTKKDSEIIIKEIKDAHKKFILEAEKSEQKI 1571

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1917 TS--HQKLEEERSVLNNQ-----LLEMKKSL---PSNTLRESTLKKEIDE---ERASLQKSISDTSalITQKDEELEKLR 1983
Cdd:TIGR01612 1572 KEikKEKFRIEDDAAKNDksnkaAIDIQLSLenfENKFLKISDIKKKINDclkETESIEKKISSFS--IDSQDTELKENG 1649

                         1290      1300      1310
                   ....*....|....*....|....*....|....*....
gi 2024359622 1984 NEITvlrgenasakTLQSVVKTLESDKLKLEEKVKNLEQ 2022
Cdd:TIGR01612 1650 DNLN----------SLQEFLESLKDQKKNIEDKKKELDE 1678
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1432-1986 1.04e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1432 EKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQeldfsakRLLVQENTTLKYSIEALEEELKKKNLENQELIAC 1511
Cdd:COG1196    224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAEL-------AELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1512 RSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKAR-- 1589
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELae 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1590 -ILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKS 1668
Cdd:COG1196    377 aEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1669 DFTSLSVSKAELEDVHSCVSVMLDELQHKYEvtEKEKMELVQENESLHAEWKSLVIINEEILKEKEKLSKEYYKLH--EK 1746
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELA--EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgvEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1747 VVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKI 1826
Cdd:COG1196    535 AYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1827 ETL--ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1904
Cdd:COG1196    615 YYVlgDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1905 LAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRN 1984
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER 774


                   ..
gi 2024359622 1985 EI 1986
Cdd:COG1196    775 EI 776
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 905-1103 1.59e-07

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 55.99  E-value: 1.59e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  905 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDlQAK 984
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE-LEALQAEIDKLQAEIAEAEAEIEERREELGE-RAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  985 YEKETSEMITKHDA-----DIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1059
Cdd:COG3883     94 ALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359622 1060 RDLISEKE----TLAQERNTLKLEKESLLSQHLEMESKILLVQQDREE 1103
Cdd:COG3883    174 EAQQAEQEallaQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 344-1086 2.69e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 2.69e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  344 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALV---RDGHDRHVLEMEAKMDQLRAMVEAADREKVELLN 420
Cdd:pfam02463  242 LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQeeeLKLLAKEEEELKSELLKLERRKVDDEEKLKESEK 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  421 QLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKE-----------VAELRGRL 489
Cdd:pfam02463  322 EKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLEserlssaaklkEEELELKS 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  490 ESSKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHAN 569
Cdd:pfam02463  402 EEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVK 481

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  570 KENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVG---------AQTAEFAELKTQMEKVKLDYENEMSNLKLKQENE 640
Cdd:pfam02463  482 LQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgvggriisaHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  641 KSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVE--------DQHLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQT 712
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  713 KLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 792
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  793 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ--LKSNLTVMETKLKEREE 870
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKteKLKVEEEKEEKLKAQEE 801

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  871 REqqltEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNV----EQTAQKAEQSQ 946
Cdd:pfam02463  802 EL----RALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEitkeELLQELLLKEE 877

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  947 QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELET 1026
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1027 QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1086
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 939-1183 3.72e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  939 AQKAEQSQQEtLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAAQ 1018
Cdd:COG4942     19 ADAAAEAEAE-LEQLQQEIAELEKELAALKKEEKALLKQLAALERR--------IAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1019 KKNDELETQAEELKKQ-AEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhlemeskillv 1097
Cdd:COG4942     90 KEIAELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL-------------- 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1098 QQDREELWTKNEELNSEnkkiLKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQ 1177
Cdd:COG4942    156 RADLAELAALRAELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELA---ELAAELAELQQEAEELEAL 228


                   ....*.
gi 2024359622 1178 LKELQA 1183
Cdd:COG4942    229 IARLEA 234
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1789-2103 3.73e-07

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 55.85  E-value: 3.73e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1789 LQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIhqeKIETLASLENSRQ-------TNEKLQNELDMLKQNNLKNEEELT 1861
Cdd:COG5022    765 LQALKRIKKIQVIQHGFRLRRLVDYELKWRLFI---KLQPLLSLLGSRKeyrsylaCIIKLQKTIKREKKLRETEEVEFS 841

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1862 KSKELLNLENKKVEELKKEFEALKlaaaqKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLP 1941
Cdd:COG5022    842 LKAEVLIQKFGRSLKAKKRFSLLK-----KETIYLQSAQRVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLS 916

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1942 SNTLRESTLKKEID--EERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKN 2019
Cdd:COG5022    917 SDLIENLEFKTELIarLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKN 996

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 2020 LEQKLKAKSEQPLTVTSPSGDiaANLLQDESAEdKQQEIDFLNSVIVDLQRRNEELNLKiqRMCEAALNGNEEETINYDS 2099
Cdd:COG5022    997 FKKELAELSKQYGALQESTKQ--LKELPVEVAE-LQSASKIISSESTELSILKPLQKLK--GLLLLENNQLQARYKALKL 1071


                   ....
gi 2024359622 2100 EEEG 2103
Cdd:COG5022   1072 RREN 1075
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
626-1089 3.75e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.54  E-value: 3.75e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  626 YENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE------EKEQTLENLKAKLESVEDQ--HLVEMEDTLNKLQEAEIK 697
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEkeeeyaELQEELEELEEELEELEAEleELREELEKLEKLLQLLPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  698 VKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSN 776
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  777 LTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKS 856
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  857 NLTVMETKLKEREEREQQLTEAKVKLEN-DIAEIMKSSGDSSAQLmkmNDELRLKERQLEQIQLELTKANEKAVQLQknv 935
Cdd:COG4717    291 LLLAREKASLGKEAEELQALPALEELEEeELEELLAALGLPPDLS---PEELLELLDRIEELQELLREAEELEEELQ--- 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  936 eqtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDA-DIKGFKQNLLDAEEAL 1014
Cdd:COG4717    365 ---LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAlDEEELEEELEELEEEL 441

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1015 KAAQKKNDELETQAEELKKQAEQAKSlSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKEsLLSQHLE 1089
Cdd:COG4717    442 EELEEELEELREELAELEAELEQLEE-DGELAELLQELE-------ELKAELRELAEEWAALKLALE-LLEEARE 507
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 557-1343 4.35e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 55.50  E-value: 4.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  557 ENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKvsfnKGVGAQTAEFAELKTQMEKVKLDYENEMS-NLKL 635
Cdd:pfam05483   71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENR----KIIEAQRKAIQELQFENEKVSLKLEEEIQeNKDL 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  636 KQENEKSQH----LKEIEALKAKLLEVTE-EKEQT----------LENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKE 700
Cdd:pfam05483  147 IKENNATRHlcnlLKETCARSAEKTKKYEyEREETrqvymdlnnnIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQH 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  701 LDV-LQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKansEGKLEIQKLSEQLQAAEKQIQNLETEKvggsskvSNLTK 779
Cdd:pfam05483  227 LEEeYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLE---ESRDKANQLEEKTKLQDENLKELIEKK-------DHLTK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  780 ELQgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENaqramqeTINKLNQKEEQFALMSSELEQLKSNLT 859
Cdd:pfam05483  297 ELE-------DIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEA-------QMEELNKAKAAHSFVVTEFEATTCSLE 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  860 -VMETKLKEREEREQQLTEAKVKLENdiaeimkssgdSSAQLMKMNDELRLKERQLEQIQLELTKaNEKAVQLQKNVEQT 938
Cdd:pfam05483  363 eLLRTEQQRLEKNEDQLKIITMELQK-----------KSSELEEMTKFKNNKEVELEELKKILAE-DEKLLDEKKQFEKI 430

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  939 AQKAEQSQQET---LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsemitkhdadikgfkqnlldaeealk 1015
Cdd:pfam05483  431 AEELKGKEQELiflLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKE--------------------------- 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1016 aaQKKNDELETQAEEL----KKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLlsqhleme 1091
Cdd:pfam05483  484 --KLKNIELTAHCDKLllenKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESV-------- 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1092 skillvqqdREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSE 1171
Cdd:pfam05483  554 ---------REEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKG 624

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1172 STLLQQLK--ELQANKDAVDVACQKHiKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTA 1249
Cdd:pfam05483  625 SAENKQLNayEIKVNKLELELASAKQ-KFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIA 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1250 ERDSAQEKDldlKSTHIALKNEIDCLLQTNRSLQSEKEMLlksREELCVSLANTANENQALKlrkdemqTELETEREKLE 1329
Cdd:pfam05483  704 EMVALMEKH---KHQYDKIIEERDSELGLYKNKEQEQSSA---KAALEIELSNIKAELLSLK-------KQLEIEKEEKE 770

                          810
                   ....*....|....
gi 2024359622 1330 KMTKDNMDLKASLS 1343
Cdd:pfam05483  771 KLKMEAKENTAILK 784
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 835-1472 4.65e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 4.65e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  835 NKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL 914
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  915 EQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQeELKKMQDQLTDMKKQMEtsqnQYKDLQAKYEKETSEmIT 994
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEK-ELEKLNNKYNDLKKQKE----ELENELNLLEKEKLN-IQ 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  995 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKslssvlasarKEIELMSDKMRDLISEKETLAQERN 1074
Cdd:TIGR04523  187 KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLK----------DNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1075 TLKLEKESLLSQhleMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETaq 1154
Cdd:TIGR04523  257 QLKDEQNKIKKQ---LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSE---LKNQEKKLEEIQN-- 328

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1155 adllKITQENDALRSSESTlLQQLKELQANKDAVDVACQKHIKERE-ELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDL 1233
Cdd:TIGR04523  329 ----QISQNNKIISQLNEQ-ISQLKKELTNSESENSEKQRELEEKQnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQ 403

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1234 ARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLR 1313
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1314 KDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEK------IHLLQEALFASEQRLLAER-EELV 1386
Cdd:TIGR04523  484 LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskISDLEDELNKDDFELKKENlEKEI 563

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1387 NENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDM 1466
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643


                   ....*.
gi 2024359622 1467 KREQEL 1472
Cdd:TIGR04523  644 KQEVKQ 649
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
634-1053 5.45e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 54.77  E-value: 5.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  634 KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTK 713
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREEL-----EKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  714 LIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQL-QAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLE 792
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  793 KNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREERE 872
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  873 QQLTEAKVKLEN-DIAEIMKSSG--------------DSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ 937
Cdd:COG4717    307 LQALPALEELEEeELEELLAALGlppdlspeellellDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  938 TAQKAEQSQQetLKTHQEELKKMQDQLTDMKKQMET--SQNQYKDLQAKYE------KETSEMITKHDADIKGFKQNLLD 1009
Cdd:COG4717    387 LRAALEQAEE--YQELKEELEELEEQLEELLGELEEllEALDEEELEEELEeleeelEELEEELEELREELAELEAELEQ 464

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359622 1010 AEEALKAAQKKnDELETQAEELKKQAEQAKSL---SSVLASARKEIE 1053
Cdd:COG4717    465 LEEDGELAELL-QELEELKAELRELAEEWAALklaLELLEEAREEYR 510
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 577-1037 6.82e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 54.96  E-value: 6.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKleSAIASHQQAMEELkvsfnkgvgaqTAEFAELKTQMEKVKLDYENEMSNLKLKQE----NEKSQHLKE-IEAL 651
Cdd:COG3096    293 ELFGAR--RQLAEEQYRLVEM-----------ARELEELSARESDLEQDYQAASDHLNLVQTalrqQEKIERYQEdLEEL 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  652 KAKLlevtEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASE 726
Cdd:COG3096    360 TERL----EEQEEVVEEAAEQLAEAEAR-----------LEAAEEEVDSLksqlaDYQQALDVQQTRAI-QYQQAVQALE 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  727 E--KLLDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDS 804
Cdd:COG3096    424 KarALCGLPDLTPENAEDYLA------AFRAKEQQA------------------------TEEVLELEQKLSVADAARRQ 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  805 LEKELQLLkEKFTSAVDGAENAQRAmQETINKLnqkeeqfalmsSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEn 884
Cdd:COG3096    474 FEKAYELV-CKIAGEVERSQAWQTA-RELLRRY-----------RSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLE- 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  885 diaEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQL 964
Cdd:COG3096    540 ---EFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKE-----LAARAPAWLAAQDAL 611

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359622  965 TDMKKQmetSQNQYKDLQakyeketsemitkhdaDIKGFKQNLLDAEEALKAAQkknDELETQAEELKKQAEQ 1037
Cdd:COG3096    612 ERLREQ---SGEALADSQ----------------EVTAAMQQLLEREREATVER---DELAARKQALESQIER 662
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1447-2021 7.01e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.94  E-value: 7.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1447 RKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIACRSDLSDLLKEAQDAR 1526
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAE-----LEELEAELAELEAELEELRLELEELELELEEAQAEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1527 RTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNn 1606
Cdd:COG1196    291 YELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE- 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1607 igfLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSC 1686
Cdd:COG1196    370 ---AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1687 VSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLvIINEEILKEKEKLSKEYYKLHE------KVVALLEQTDADFSC 1760
Cdd:COG1196    447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAEL-LEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGA 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1761 RLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNE 1840
Cdd:COG1196    526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1841 KLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLA-ALQEENVKLAEELGRSRDEVTSH 1919
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSlTGGSRRELLAALLEAEAELEELA 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1920 QKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTL 1999
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765

                          570       580
                   ....*....|....*....|..
gi 2024359622 2000 QSVVKtlesdklKLEEKVKNLE 2021
Cdd:COG1196    766 ERELE-------RLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 335-694 8.01e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 54.68  E-value: 8.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  335 ARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDR----------HVLEMEAKMDQL 404
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEElsrqisalrkDLARLEAEVEQL 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  405 RAMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDpenvATVSEKSRIMELERDLALRVKEVAE 484
Cdd:TIGR02168  746 EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKE----ELKALREALDELRAELTLLNEEAAN 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  485 LRGRLESS-KHIDDVDTSLS-LLQEISSLQEKMAAAGKEhQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLK 562
Cdd:TIGR02168  822 LRERLESLeRRIAATERRLEdLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLNERASLEEALALLRSELEELS 900

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  563 TKLDHANKENSDVIELwKSKLESAIASHQQAMEELKVsfnkgvgaqtaEFAELKTQ-MEKVKLDYEN--EMSNLKLKQEN 639
Cdd:TIGR02168  901 EELRELESKRSELRRE-LEELREKLAQLELRLEGLEV-----------RIDNLQERlSEEYSLTLEEaeALENKIEDDEE 968

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  640 EKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEA 694
Cdd:TIGR02168  969 EARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQK-EDLTEAKETLEEA 1022
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 419-1126 8.14e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 8.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  419 LNQLEEEKRKVEDLQFRVEEEsitkgdlerkrqisedpenvatvseksrIMELERDLALRVKEVAELRGRLESSKhiddv 498
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTE----------------------------IKKKEKELEKLNNKYNDLKKQKEELE----- 172

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  499 DTSLSLLQEISSLQEKMAAAGKEHQRemsslKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKEnsdviel 578
Cdd:TIGR04523  173 NELNLLEKEKLNIQKNIDKIKNKLLK-----LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQE------- 240

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  579 wKSKLESAIASHQQAMEELKVSFNKgvgaqtaefaeLKTQMEKVKLDYENemSNLKLKQENeksqhlKEIEALKAKLLEV 658
Cdd:TIGR04523  241 -INEKTTEISNTQTQLNQLKDEQNK-----------IKKQLSEKQKELEQ--NNKKIKELE------KQLNQLKSEISDL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  659 TEEKEQ-TLENLKAKLESVEdqhlvemedtlnklqeaeikvKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDL----A 733
Cdd:TIGR04523  301 NNQKEQdWNKELKSELKNQE---------------------KKLEEIQNQISQNNKIISQLNEQISQLKKELTNSesenS 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  734 ALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNlsavnqvKDSLEKELQLLK 813
Cdd:TIGR04523  360 EKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE-------KELLEKEIERLK 432

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  814 EKFT---SAVDGAENAQRAMQETINKLNQK----EEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDI 886
Cdd:TIGR04523  433 ETIIknnSEIKDLTNQDSVKELIIKNLDNTreslETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKV 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  887 AEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANE--KAVQLQKNVEQTAQKAEQsqqetLKTHQEELKKMQDQL 964
Cdd:TIGR04523  513 KDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelKKENLEKEIDEKNKEIEE-----LKQTQKSLKKKQEEK 587

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  965 TDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfkqnlldaEEALKAAQKKNDELETQAEELKKQAEQAKSLSSV 1044
Cdd:TIGR04523  588 QELIDQKEKEKKDLIKEIEEKEKKISSL------------------EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQ 649

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1045 LASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEA 1124
Cdd:TIGR04523  650 IKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKE 729


                   ..
gi 2024359622 1125 AE 1126
Cdd:TIGR04523  730 LE 731
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 733-1472 8.28e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.59  E-value: 8.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  733 AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQkllDLEKNLSAVNQVKDSLEKELQLL 812
Cdd:TIGR00618  155 AQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL---CTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  813 KEkftsavdgaenAQRAMQETINKLNQKEEQFALMSS---ELEQLKSNLTVMETKLKEREEREQQLTEAKVKLEndIAEI 889
Cdd:TIGR00618  232 RE-----------ALQQTQQSHAYLTQKREAQEEQLKkqqLLKQLRARIEELRAQEAVLEETQERINRARKAAP--LAAH 298

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  890 MKSSGDSSAQLMKMNDELRLKERQLEQI--QLELTKANEKAVQLQKNVEQTAQKAEQ------SQQETLKTHQEELKKMQ 961
Cdd:TIGR00618  299 IKAVTQIEQQAQRIHTELQSKMRSRAKLlmKRAAHVKQQSSIEEQRRLLQTLHSQEIhirdahEVATSIREISCQQHTLT 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  962 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK--HDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK 1039
Cdd:TIGR00618  379 QHIHTLQQQKTTLTQKLQSLCKELDILQREQATIdtRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEK 458

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1040 SLSSVLASARKEIElmsdkmrDLISEKETLAQERNTLKLEKESLLSQHLEMESkiLLVQQDREELWTKNEELNSENKKIL 1119
Cdd:TIGR00618  459 IHLQESAQSLKERE-------QQLQTKEQIHLQETRKKAVVLARLLELQEEPC--PLCGSCIHPNPARQDIDNPGPLTRR 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1120 KQKEAAEAKSRQESTEKV-----ALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK 1194
Cdd:TIGR00618  530 MQRGEQTYAQLETSEEDVyhqltSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1195 HIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEvSILTAERDSAQEKDLDLKSTHIALKneidc 1274
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQE-RVREHALSIRVLPKELLASRQLALQ----- 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1275 llqtnrSLQSEKEMLLKSREELcvslantaneNQALKLRKDEMQTELETEREkLEKMTKDNMDLKASLSSLSNFLEEMKS 1354
Cdd:TIGR00618  684 ------KMQSEKEQLTYWKEML----------AQCQTLLRELETHIEEYDRE-FNEIENASSSLGSDLAAREDALNQSLK 746

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1355 SREASNSEKIHLLQEALFASEQRLL------AEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS 1428
Cdd:TIGR00618  747 ELMHQARTVLKARTEAHFNNNEEVTaalqtgAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL 826

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359622 1429 LQFEKHNEALLREKD----ELERKYSELLDEKKSLENAFSDMKREQEL 1472
Cdd:TIGR00618  827 VQEEEQFLSRLEEKSatlgEITHQLLKYEECSKQLAQLTQEQAKIIQL 874
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 752-952 1.13e-06

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 53.30  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  752 QLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQ 831
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  832 ETINKLNQKEeqFALMSSELEQLKSNLTVMET-------KLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMN 904
Cdd:COG3883     97 RSGGSVSYLD--VLLGSESFSDFLDRLSALSKiadadadLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 2024359622  905 DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKT 952
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAA 222
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1486-2008 1.35e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.89  E-value: 1.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1486 TLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLEnelaavshakqVLSSSFNTCSSDIEILNRERTELQ 1565
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-----------TLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1566 DKCQKLTGEVENMKENLT---VEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKL 1642
Cdd:PRK02224   279 EEVRDLRERLEELEEERDdllAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1643 EEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSL 1722
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1723 viinEEILKEKEKLskeyykLHEKVVALLEQT--DADFSCRLLVSEGKHELLLEEMSNLALKLREIE-RLQAQTFMQKFE 1799
Cdd:PRK02224   439 ----RERVEEAEAL------LEAGKCPECGQPveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEeRLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1800 AD-KRAEEVLQTMEKVTKEKDAIHQEKIETLASLensRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1878
Cdd:PRK02224   509 DRiERLEERREDLEELIAERRETIEEKRERAEEL---RERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELK 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1879 KEFEALK------LAAAQKSQQLAALQEENVKLAEELGRSRDEVTS----HQKLEEERSVLNNQLLEMKKSLPSNTLRES 1948
Cdd:PRK02224   586 ERIESLErirtllAAIADAEDEIERLREKREALAELNDERRERLAEkrerKRELEAEFDEARIEEAREDKERAEEYLEQV 665

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1949 TLK-KEIDEERASLQKSIsdtsALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLES 2008
Cdd:PRK02224   666 EEKlDELREERDDLQAEI----GAVENELEELEELRERREALENRVEALEALYDEAEELES 722
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1491-2041 1.56e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1491 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSH---AKQVLSSSFNTCSSDIEILNRERTELQDK 1567
Cdd:TIGR04523  147 IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNkllKLELLLSNLKKKIQKNKSLESQISELKKQ 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1568 CQKLTGEVENMKENLtVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEkekSETKLEEVIK 1647
Cdd:TIGR04523  227 NNQLKDNIEKKQQEI-NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQ---LKSEISDLNN 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1648 EKMilyketeqlASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIINE 1727
Cdd:TIGR04523  303 QKE---------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1728 EILKEKEKLSKEYYKLHEKVVALLEQtdadFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRAEE- 1806
Cdd:TIGR04523  374 KLKKENQSYKQEIKNLESQINDLESK----IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQd 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1807 -VLQTMEKVTKEKDAIHQEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEAL 1884
Cdd:TIGR04523  450 sVKELIIKNLDNTRESLETQLKVLsRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKL 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1885 KLAAAQKSQQLAALQEENVKLAEELGRSrdevtshqKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEerasLQKS 1964
Cdd:TIGR04523  530 ESEKKEKESKISDLEDELNKDDFELKKE--------NLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ----KEKE 597

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359622 1965 ISDTSALITQKDEELEKLRNEITVLRGENasaktlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDI 2041
Cdd:TIGR04523  598 KKDLIKEIEEKEKKISSLEKELEKAKKEN----------EKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEI 664
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
957-1507 1.75e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.75e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  957 LKKMQDQLTDMKKQMEtsQNQYKDLQAK---YEKETSEMitkhDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKK 1033
Cdd:PRK02224   182 LSDQRGSLDQLKAQIE--EKEEKDLHERlngLESELAEL----DEEIERYEEQREQARETRDEADEVLEEHEERREELET 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1034 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL-------KLEKESLLSQHLEMESKILLVQQDREELWT 1106
Cdd:PRK02224   256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1107 KNEELNSENKKILkqKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQADLLKITQENDALRSsestllqqlkELQANKD 1186
Cdd:PRK02224   336 AAQAHNEEAESLR--EDADDLEERAEELR-----EEAAELESELEEAREAVEDRREEIEELEE----------EIEELRE 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1187 AVDVACQkhikEREELEHYQKLLEEN-DRVIKDKDDVIQRLQSSYDDLARNQR--------ELLQEVS----ILTAERDS 1253
Cdd:PRK02224   399 RFGDAPV----DLGNAEDFLEELREErDELREREAELEATLRTARERVEEAEAlleagkcpECGQPVEgsphVETIEEDR 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1254 AQEKDL-----DLKSTHIALKNEIDcLLQTNRSLQSEKEMLLKSRE---ELCVSLANTANEN----QALKLRKDEMQTEL 1321
Cdd:PRK02224   475 ERVEELeaeleDLEEEVEEVEERLE-RAEDLVEAEDRIERLEERREdleELIAERRETIEEKreraEELRERAAELEAEA 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1322 ETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNS-EKIHLLQEALFASEQRLLAEREELVNENKAVTEKL-TKA 1399
Cdd:PRK02224   554 EEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERiRTLLAAIADAEDEIERLREKREALAELNDERRERLaEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1400 TADAVLAETAFTEKINELNLEKEsvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKR-EQELDFSAKR 1478
Cdd:PRK02224   634 ERKRELEAEFDEARIEEAREDKE-------RAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEElRERREALENR 706

                          570       580       590
                   ....*....|....*....|....*....|....
gi 2024359622 1479 L-----LVQENTTLKYSIEALEEELKKKNLENQE 1507
Cdd:PRK02224   707 VealeaLYDEAEELESMYGDLRAELRQRNVETLE 740
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 692-1214 3.39e-06

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 52.45  E-value: 3.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  692 QEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 771
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  772 SKVSNLTKELQGKEQKLLdlEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSEL 851
Cdd:pfam07111  143 EEIQRLHQEQLSSLTQAH--EEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLV 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  852 EQLKSNL---TVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQL-------------- 914
Cdd:pfam07111  221 ESLRKYVgeqVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTHMLALQEEELtrkiqpsdslepef 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  915 -EQIQLELTKANEKAVQLQknVEQTAQKAEQSqqETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM- 992
Cdd:pfam07111  301 pKKCRSLLNRWREKVFALM--VQLKAQDLEHR--DSVKQLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAk 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  993 -----ITKHDADIKGFKQNLLDAEEALK----AAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIElmsdKMRDLI 1063
Cdd:pfam07111  377 glqmeLSRAQEARRRQQQQTASAEEQLKfvvnAMSSTQIWLETTMTRVEQAVARIPSLSNRLSYAVRKVH----TIKGLM 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1064 SEKETLAQerntLKLEKESLLSQHLEMESKILL-VQQDREELWTKNEELNSENKKIlkQKEAAEAKSRQEStEKVALISE 1142
Cdd:pfam07111  453 ARKVALAQ----LRQESCPPPPPAPPVDADLSLeLEQLREERNRLDAELQLSAHLI--QQEVGRAREQGEA-ERQQLSEV 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1143 KSKLLSEIETAQADLLKITQENDALRSSESTLLQQL----KELQANKDAVDVACQKHIKE-----REELEHYQKLLEEND 1213
Cdd:pfam07111  526 AQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAaslrQELTQQQEIYGQALQEKVAEvetrlREQLSDTKRRLNEAR 605


                   .
gi 2024359622 1214 R 1214
Cdd:pfam07111  606 R 606
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 396-1507 3.55e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.75  E-value: 3.55e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  396 EMEAKMDQLRAMVEAADREKVELLNQLEEEKRKVEDLQFRVEeesitkgDLERKrQISEDPENVatvseksRIMELERDL 475
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIK-------DLFDK-YLEIDDEII-------YINKLKLEL 605

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  476 ALRVKEVAE----LRGRLESSKHIDDVDTSLSLLQEISSLQ--EKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSA 549
Cdd:TIGR01612  606 KEKIKNISDkneyIKKAIDLKKIIENNNAYIDELAKISPYQvpEHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVK 685

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  550 SNERMGKEN----ESLKTKLDHA-----NKENSDV------IELWKSKLESAIASHQQAME-ELKVSFNKGVGAQTAEFA 613
Cdd:TIGR01612  686 ENAIDNTEDkaklDDLKSKIDKEydkiqNMETATVelhlsnIENKKNELLDIIVEIKKHIHgEINKDLNKILEDFKNKEK 765

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  614 ELKTQMEKVKlDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAkLESVEDQHLVEMEDTLNKLQE 693
Cdd:TIGR01612  766 ELSNKINDYA-KEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKT-ISIKEDEIFKIINEMKFMKDD 843

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  694 AEIKVKELDVLQAKCNEQT----KLIGSLTQQIRA--SEEKLLDLAalQKANSEGKLeiqkLSEQLQAAEKQIQNLET-E 766
Cdd:TIGR01612  844 FLNKVDKFINFENNCKEKIdsehEQFAELTNKIKAeiSDDKLNDYE--KKFNDSKSL----INEINKSIEEEYQNINTlK 917

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  767 KVGGSSKVSNLTKElqgkeqkllDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFAL 846
Cdd:TIGR01612  918 KVDEYIKICENTKE---------SIEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASL 988

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  847 MSSE---------LEQLKSNL-----TVMETKLKEREEREQQLTEAKVKLENDIAEI-------MKSSGDSSAQLMKMND 905
Cdd:TIGR01612  989 NDYEaknnelikyFNDLKANLgknkeNMLYHQFDEKEKATNDIEQKIEDANKNIPNIeiaihtsIYNIIDEIEKEIGKNI 1068

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  906 ELrLKERQLEQIQLELTKANEKAVQLqknveQTAQKAEQSQQETLKtHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKY 985
Cdd:TIGR01612 1069 EL-LNKEILEEAEINITNFNEIKEKL-----KHYNFDDFGKEENIK-YADEINKIKDDIKNLDQKIDHHIKALEEIKKKS 1141

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  986 EKETSEMITKHDaDIKGFKQNLLdAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLAsarkEIELMSDKMRDLISE 1065
Cdd:TIGR01612 1142 ENYIDEIKAQIN-DLEDVADKAI-SNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIA----EIEKDKTSLEEVKGI 1215

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1066 KETLAQERNTLKLEK---ESLLSQHL--EMESKIllvqQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALI 1140
Cdd:TIGR01612 1216 NLSYGKNLGKLFLEKideEKKKSEHMikAMEAYI----EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHI 1291

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1141 SEKS--KLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKDAVDVACQK-----------HIKE-REELEHYQ 1206
Cdd:TIGR01612 1292 ISKKhdENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEianiynilklnKIKKiIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1207 KLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE 1285
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLiKKIKDDINLEECKSKIESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1286 KEMLLKSREelcvsLANTANEnQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIH 1365
Cdd:TIGR01612 1452 VLLLFKNIE-----MADNKSQ-HILKIKKDNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTE 1525

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1366 LLQEalfASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREK--- 1442
Cdd:TIGR01612 1526 LLNK---YSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQlsl 1602

                         1130      1140      1150      1160      1170      1180      1190
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1443 DELERKYSELLDEKKSLENAFSDM----KREQELDFSAKRLLVQENTTLKYSIEALEEELK--KKNLENQE 1507
Cdd:TIGR01612 1603 ENFENKFLKISDIKKKINDCLKETesieKKISSFSIDSQDTELKENGDNLNSLQEFLESLKdqKKNIEDKK 1673
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1351-2030 4.30e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 4.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1351 EMKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKS-- 1428
Cdd:TIGR00618  179 TQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkk 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1429 -------------LQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKRE----QELDFSAKRLLVQENTTLKYSI 1491
Cdd:TIGR00618  259 qqllkqlrarieeLRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIhtelQSKMRSRAKLLMKRAAHVKQQS 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1492 EALEEELKKKNLENQE-LIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRErtelQDKCQK 1570
Cdd:TIGR00618  339 SIEEQRRLLQTLHSQEiHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQRE----QATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1571 LTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEK---EKSETKLEEVIK 1647
Cdd:TIGR00618  415 RTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1648 EKMILYKETEQLASKIEQLKSDFTSLSVSKA------ELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKS 1721
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrrmqRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1722 LVIINEEILKEKEKLSKEyyklhekVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQTFMQKFEAD 1801
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNI-------TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1802 KRAEEVLQTMEKVTKEKDAIHQEKIETLASlensrqtNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEF 1881
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKELLAS-------RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1882 EALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKeidEERASL 1961
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFN---RLREED 797

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1962 QKSISDTSALITQK--DEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 2030
Cdd:TIGR00618  798 THLLKTLEAEIGQEipSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQ 868
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 570-1953 6.78e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.59  E-value: 6.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  570 KENSDVIELWKSKLESAIASHQQAMEELKVSFN----KGVGAQTAEFAELKTQMEKVKLDYenemsNLKLKQENEKSQHL 645
Cdd:TIGR01612  503 KDFKDIIDFMELYKPDEVPSKNIIGFDIDQNIKaklyKEIEAGLKESYELAKNWKKLIHEI-----KKELEEENEDSIHL 577

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  646 -KEIEALKAKLLEVTEE----KEQTLEnLKAKLESVED--QHLVEMEDTLNKLQEAEIKVKELDVLQA-KCNEQTKLIGS 717
Cdd:TIGR01612  578 eKEIKDLFDKYLEIDDEiiyiNKLKLE-LKEKIKNISDknEYIKKAIDLKKIIENNNAYIDELAKISPyQVPEHLKNKDK 656

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  718 LTQQIRASEEKLL--DLAALQKA-----------NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGgsskvSNLTKeLQGK 784
Cdd:TIGR01612  657 IYSTIKSELSKIYedDIDALYNElssivkenaidNTEDKAKLDDLKSKIDKEYDKIQNMETATVE-----LHLSN-IENK 730

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  785 EQKLLDLEKNLSavNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNL------ 858
Cdd:TIGR01612  731 KNELLDIIVEIK--KHIHGEINKDLNKILEDF-------KNKEKELSNKINDYAKEKDELNKYKSKISEIKNHYndqini 801

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  859 -TVMETKLKEREEREQQLTEAKVKLENDIAEIMKssgdssaQLMKMNDELrlkerqleqiqleLTKANeKAVQLQKNVEQ 937
Cdd:TIGR01612  802 dNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIIN-------EMKFMKDDF-------------LNKVD-KFINFENNCKE 860

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  938 TAQKAEQSQQETLKTHQEELKkmQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADikGFKQNLLDAEEALKAA 1017
Cdd:TIGR01612  861 KIDSEHEQFAELTNKIKAEIS--DDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVD--EYIKICENTKESIEKF 936

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1018 QKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIElmsdkmrdlisekETLAQERNTL-KLEKESLLSQHLEMESKILL 1096
Cdd:TIGR01612  937 HNKQNILK---EILNKNIDTIKESNLIEKSYKDKFD-------------NTLIDKINELdKAFKDASLNDYEAKNNELIK 1000

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1097 VQQDREELWTKNEElnsenkKILKQKEAAEAKSRQESTEKvalISEKSKLLSEIETA-QADLLKITQENDAL--RSSEST 1173
Cdd:TIGR01612 1001 YFNDLKANLGKNKE------NMLYHQFDEKEKATNDIEQK---IEDANKNIPNIEIAiHTSIYNIIDEIEKEigKNIELL 1071

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1174 LLQQLKELQANkdavdVACQKHIKEREELEHYQKLLEENDrvIKDKDDViqrlQSSYDDLARNQRELLQEVSILTAERDS 1253
Cdd:TIGR01612 1072 NKEILEEAEIN-----ITNFNEIKEKLKHYNFDDFGKEEN--IKYADEI----NKIKDDIKNLDQKIDHHIKALEEIKKK 1140

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1254 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMllksrEELCVSLANTANENQALKLRKDEMqTELETEREKLEKMTK 1333
Cdd:TIGR01612 1141 SENYIDEIKAQINDLEDVADKAISNDDPEEIEKKI-----ENIVTKIDKKKNIYDEIKKLLNEI-AEIEKDKTSLEEVKG 1214

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1334 DNMDLKASLSSLsnFLEEMKSSREASnsekihllqEALFASEQRLLAEREELvnenkavtEKLTKATADAVLAETAFTEK 1413
Cdd:TIGR01612 1215 INLSYGKNLGKL--FLEKIDEEKKKS---------EHMIKAMEAYIEDLDEI--------KEKSPEIENEMGIEMDIKAE 1275

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1414 INELNLEKESVFSKSLQFEKHNEAL--LREKD----ELERKYSELLDEKKSLENAFSDMKREQeldfSAKRLLVQENTTL 1487
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENIsdIREKSlkiiEDFSEESDINDIKKELQKNLLDAQKHN----SDINLYLNEIANI 1351

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1488 kYSIEALEeelKKKNLENQeliacrsdLSDLLKEAQDARRTLENELAAVSHAKQVL--SSSFNTCSSDIEilnrerTELQ 1565
Cdd:TIGR01612 1352 -YNILKLN---KIKKIIDE--------VKEYTKEIEENNKNIKDELDKSEKLIKKIkdDINLEECKSKIE------STLD 1413

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1566 DKcqKLTGEVENMKENltvekKARILDKES----FLLERMELQNNIGFLEKEVEEMREKNKEFLTEKE------------ 1629
Cdd:TIGR01612 1414 DK--DIDECIKKIKEL-----KNHILSEESnidtYFKNADENNENVLLLFKNIEMADNKSQHILKIKKdnatndhdfnin 1486

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1630 LLVQEKEKSETKLEEVIKEKmilyKETEQLASKIEQLKSDFTSLSVSKAELedvhscvsvmldELQHKYEVTEKEKMELV 1709
Cdd:TIGR01612 1487 ELKEHIDKSKGCKDEADKNA----KAIEKNKELFEQYKKDVTELLNKYSAL------------AIKNKFAKTKKDSEIII 1550

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1710 QENESLHaewKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLleEMSNLALK----LRE 1785
Cdd:TIGR01612 1551 KEIKDAH---KKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFL--KISDIKKKindcLKE 1625

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1786 IERLQAQ-------TFMQKFEADKRAEEVLQT-MEKVTKEKDAIHQEKIEtlasLENSRQTNEKLQNELDMLKQN----- 1852
Cdd:TIGR01612 1626 TESIEKKissfsidSQDTELKENGDNLNSLQEfLESLKDQKKNIEDKKKE----LDELDSEIEKIEIDVDQHKKNyeigi 1701

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1853 -------NLKNEEELTKSKELLnleNKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEE 1925
Cdd:TIGR01612 1702 iekikeiAIANKEEIESIKELI---EPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSK 1778

                         1450      1460
                   ....*....|....*....|....*...
gi 2024359622 1926 RSVLNNQLLEMKKSLPSNTLRESTLKKE 1953
Cdd:TIGR01612 1779 EPITYDEIKNTRINAQNEFLKIIEIEKK 1806
COG5022 COG5022
Myosin heavy chain [General function prediction only];
625-1385 6.82e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 51.62  E-value: 6.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  625 DYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKA----KLESVEDQHLVEMEDTLNKLQEAEIKVKE 700
Cdd:COG5022    814 SYLACIIKLQKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRfsllKKETIYLQSAQRVELAERQLQELKIDVKS 893

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  701 LDVLQAKCNEQTKLIGSLTQQIRASeeklldlaalqkansegkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTK- 779
Cdd:COG5022    894 ISSLKLVNLELESEIIELKKSLSSD-----------------------LIENLEFKTELIARLKKLLNNIDLEEGPSIEy 950

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  780 ELQGKEQKLLDLEKNLSAVNQVKDSLEKElqllkekftsavdgaenaqraMQETINKLNQKEEQFALMSSELEQLKSNLT 859
Cdd:COG5022    951 VKLPELNKLHEVESKLKETSEEYEDLLKK---------------------STILVREGNKANSELKNFKKELAELSKQYG 1009

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  860 VMETKLKEREEREQQLTEakvkLENDIAeIMKSSGDSSAQLMKMNDELRLKERQLEQiqlelTKANEKAVQLQknveqta 939
Cdd:COG5022   1010 ALQESTKQLKELPVEVAE----LQSASK-IISSESTELSILKPLQKLKGLLLLENNQ-----LQARYKALKLR------- 1072

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  940 qkaeqsqqetlkthqeelKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemitkhdaDIKGFKQNLLDAEEAL---KA 1016
Cdd:COG5022   1073 ------------------RENSLLDDKQLYQLESTENLLKTINVK--------------DLEVTNRNLVKPANVLqfiVA 1120

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 AQKKNDELetqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILL 1096
Cdd:COG5022   1121 QMIKLNLL----QEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLSS 1196

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1097 VQQdrEELWTKNEELNSENKKILKQkeaaeAKSRQESTEKVALISEKSKLLSEIEtaQADLLKITQENdalRSSEStLLQ 1176
Cdd:COG5022   1197 SEV--NDLKNELIALFSKIFSGWPR-----GDKLKKLISEGWVPTEYSTSLKGFN--NLNKKFDTPAS---MSNEK-LLS 1263

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1177 QLKELQankdavDVACQKHIKEREELEHYQKLLEENDrvikdkddviqrlQSSYDDLARNQRELLQEVSiLTAERDSAQE 1256
Cdd:COG5022   1264 LLNSID------NLLSSYKLEEEVLPATINSLLQYIN-------------VGLFNALRTKASSLRWKSA-TEVNYNSEEL 1323

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1257 KDLDLKSTHIALKNEIDCLLQTNRSLQSEKEML--LKSREELCVSLANTanENQALKLRKDEMQTELETEREKLEKMTKD 1334
Cdd:COG5022   1324 DDWCREFEISDVDEELEELIQAVKVLQLLKDDLnkLDELLDACYSLNPA--EIQNLKSRYDPADKENNLPKEILKKIEAL 1401

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1335 NMDLKASLSSLSnFLEEMKSSREASNSEKIHLLQEALFASEQRLLAEREEL 1385
Cdd:COG5022   1402 LIKQELQLSLEG-KDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSLSAL 1451
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 418-995 9.19e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.88  E-value: 9.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  418 LLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEdpENVATVSEKSRIMELE-RDLALRVKEVAELRGRLESSKHID 496
Cdd:pfam05483  245 LLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQD--ENLKELIEKKDHLTKElEDIKMSLQRSMSTQKALEEDLQIA 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  497 dVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEiktlsasNERMGKENESLKTKLDHANKENSDVI 576
Cdd:pfam05483  323 -TKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-------QQRLEKNEDQLKIITMELQKKSSELE 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKlesaiASHQQAMEELKVsfnkgVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEKSQHLKEIEALKAKL 655
Cdd:pfam05483  395 EMTKFK-----NNKEVELEELKK-----ILAEDEKLLDEKKQFEKIAEELKGKEQELIfLLQAREKEIHDLEIQLTAIKT 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  656 LE---VTEEKEQTLENLKAKLESVEDQHLVEMEDTLNK--LQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLL 730
Cdd:pfam05483  465 SEehyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKelTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEM 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  731 DL--------AALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK 802
Cdd:pfam05483  545 NLrdelesvrEEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  803 DSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLnQKEEQFALMSSEleqlksnltvmetKLKEREEREQQLTEAKVKL 882
Cdd:pfam05483  625 SAENKQLNAYEIKVNKLELELASAKQKFEEIIDNY-QKEIEDKKISEE-------------KLLEEVEKAKAIADEAVKL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  883 ENDIaeimkssgdssaqlmkmndELRLKERQLEQIQL-ELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQE-ELKKM 960
Cdd:pfam05483  691 QKEI-------------------DKRCQHKIAEMVALmEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNI 751

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 2024359622  961 QDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITK 995
Cdd:pfam05483  752 KAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1034-1257 1.01e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1034 QAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNS 1113
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1114 ---ENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEN-DALRSSESTLLQQLKELQANKDAVD 1189
Cdd:COG4942     98 eleAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQaEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622 1190 VACQKHIKEREELEhyqKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEK 1257
Cdd:COG4942    178 ALLAELEEERAALE---ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
mukB PRK04863
chromosome partition protein MukB;
577-1329 1.11e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.11  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKleSAIASHQQAMEELKvsfnkgvgaqtAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQhlKEIEALKAKLL 656
Cdd:PRK04863   294 ELYTSR--RQLAAEQYRLVEMA-----------RELAELNEAESDLEQDYQAASDHLNLVQTALRQQ--EKIERYQADLE 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  657 EVTEEkeqtlenLKAKLESVEDQHLvEMEDTLNKLQEAEIKVKEL-----DVLQAKCNEQTKLIgSLTQQIRASEE--KL 729
Cdd:PRK04863   359 ELEER-------LEEQNEVVEEADE-QQEENEARAEAAEEEVDELksqlaDYQQALDVQQTRAI-QYQQAVQALERakQL 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  730 LDLAALQKANSEGKLEiqklseQLQAAEKQIqnletekvggsskvsnltkelqgkEQKLLDLEKNLSAVNQVKDSLEKEL 809
Cdd:PRK04863   430 CGLPDLTADNAEDWLE------EFQAKEQEA------------------------TEELLSLEQKLSVAQAAHSQFEQAY 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  810 QLLKekftsAVDGAENAQRAMQETINKLNQKEEQFALmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKL---ENDI 886
Cdd:PRK04863   480 QLVR-----KIAGEVSRSEAWDVARELLRRLREQRHL-AEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLgknLDDE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  887 AEIMKSSGDSSAQLMKMNDELR-LKER------QLEQIQLELTK----------ANEKAVQLQknvEQTAQKAEQSQQ-- 947
Cdd:PRK04863   554 DELEQLQEELEARLESLSESVSeARERrmalrqQLEQLQARIQRlaarapawlaAQDALARLR---EQSGEEFEDSQDvt 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  948 ETLKTHQEELKKMQ---DQLTDMKKQMEtsqNQYKDLQAKYEKETSEM------------------ITKHDA-------- 998
Cdd:PRK04863   631 EYMQQLLERERELTverDELAARKQALD---EEIERLSQPGGSEDPRLnalaerfggvllseiyddVSLEDApyfsalyg 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  999 ---------------------------------DIKGFKQNLLDAEEALKA-AQKKND-EL----------------ETQ 1027
Cdd:PRK04863   708 parhaivvpdlsdaaeqlagledcpedlyliegDPDSFDDSVFSVEELEKAvVVKIADrQWrysrfpevplfgraarEKR 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1028 AEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLA---------QERNTLKLEKESLLSQHlemESKIllvQ 1098
Cdd:PRK04863   788 IEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadpeaelRQLNRRRVELERALADH---ESQE---Q 861

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1099 QDREELWTKNEELNSENK-----KILK----QKEAAEAKSRQESTEKVAL-ISEKSKLLSEIETAQADLLKITQENDALR 1168
Cdd:PRK04863   862 QQRSQLEQAKEGLSALNRllprlNLLAdetlADRVEEIREQLDEAEEAKRfVQQHGNALAQLEPIVSVLQSDPEQFEQLK 941

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1169 SSESTLLQQLKELQANKDAVD--VACQKH-----------------IKEREELEHYQKLLEENDRVIKDKDD-------V 1222
Cdd:PRK04863   942 QDYQQAQQTQRDAKQQAFALTevVQRRAHfsyedaaemlaknsdlnEKLRQRLEQAEQERTRAREQLRQAQAqlaqynqV 1021

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1223 IQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDLKsthialKNEIDCLLQTNRSLQSEKEMLLKSREElcvslan 1302
Cdd:PRK04863  1022 LASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARAR------RDELHARLSANRSRRNQLEKQLTFCEA------- 1088

                          890       900
                   ....*....|....*....|....*..
gi 2024359622 1303 tANENQALKLRKdeMQTELETEREKLE 1329
Cdd:PRK04863  1089 -EMDNLTKKLRK--LERDYHEMREQVV 1112
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1648-2037 1.17e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 50.51  E-value: 1.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1648 EKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDvhSCVSVMLDELQHKYEVTEKEKMELVQ--ENESLHAEwkslvii 1725
Cdd:pfam17380  234 EKMERRKESFNLAEDVTTMTPEYTVRYNGQTMTEN--EFLNQLLHIVQHQKAVSERQQQEKFEkmEQERLRQE------- 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1726 NEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELlleEMSNLALKLREIERLQAQTFMQKFEADKRAE 1805
Cdd:pfam17380  305 KEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMEREREL---ERIRQEERKRELERIRQEEIAMEISRMRELE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1806 ----EVLQTMEKVTKEKDAIHQEKIetlasLENSRQTNEKLQneldMLKQNNLKNEEELTKSKELLNLEnkkvEELKKEF 1881
Cdd:pfam17380  382 rlqmERQQKNERVRQELEAARKVKI-----LEEERQRKIQQQ----KVEMEQIRAEQEEARQREVRRLE----EERAREM 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1882 EALKLAAAQKSQQLAAL-QEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEERAS 1960
Cdd:pfam17380  449 ERVRLEEQERQQQVERLrQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKA 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1961 L----QKSISDTSALITQKDEELEKLRNEITVLRGEnasaktlQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQPLTVTS 2036
Cdd:pfam17380  529 IyeeeRRREAEEERRKQQEMEERRRIQEQMRKATEE-------RSRLEAMEREREMMRQIVESEKARAEYEATTPITTIK 601


                   .
gi 2024359622 2037 P 2037
Cdd:pfam17380  602 P 602
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
659-879 1.33e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  659 TEEKEQTLENLKAKLESVEDQhlvemedtlnkLQEAEIKVKELdvlqakcnEQTKLIGSLTQQIRASEEKLldlAALQKA 738
Cdd:COG3206    170 REEARKALEFLEEQLPELRKE-----------LEEAEAALEEF--------RQKNGLVDLSEEAKLLLQQL---SELESQ 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  739 NSEGKLEIQKLSEQLQAAEKQIQNLETE--KVGGSSKVSNLTKELQGKEQKLLDLEKNLSA-----------VNQVKDSL 805
Cdd:COG3206    228 LAEARAELAEAEARLAALRAQLGSGPDAlpELLQSPVIQQLRAQLAELEAELAELSARYTPnhpdvialraqIAALRAQL 307

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622  806 EKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAK 879
Cdd:COG3206    308 QQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1656-2005 1.35e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1656 TEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQH------KYEVTEKEKMELvqENESLHAEWKSLVIINEEI 1729
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRerekaeRYQALLKEKREY--EGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1730 LKEKEKLSKEYYKLHEKVVALLEQTDAdfscrllvsegkHELLLEEMSNLALKLREIERLQAQTFMQKFEADKRA----- 1804
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEE------------IEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASlersi 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1805 EEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKqnnlkneEELTKSKELLNLENKKVEELKKEFEAL 1884
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAET 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1885 KLAAAQKSQQLAALQEENVKLAEELGRSRDEVtshQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDE---ERASL 1961
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEEL---QRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKqewKLEQL 460

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 2024359622 1962 QKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKT 2005
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
AAA_13 pfam13166
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
 595-809 1.36e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. This family includes the PrrC protein that is thought to be the active component of the anticodon nuclease.


Pssm-ID: 463796 [Multi-domain]  Cd Length: 712  Bit Score: 50.44  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  595 EELKVSFNKgvgaqtaEFAELKTQMEKVKLDYENEMSNL--KLKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAK 672
Cdd:pfam13166  271 AALEAHFDD-------EFTEFQNRLQKLIEKVESAISSLlaQLPAVSDLASLLSAFELDVEDIESEAEVLNSQLDGLRRA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  673 LESVEDQ--HLVEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLdlaalqkaNSEGKLEIQKLS 750
Cdd:pfam13166  344 LEAKRKDpfKSIELDSVDAKIESINDLVASINELIAKHNEITDNFEEEKNKAKKKLRLHL--------VEEFKSEIDEYK 415

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359622  751 EQLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKEL 809
Cdd:pfam13166  416 DKYAGLEKAINSLEKEI-------KNLEAEIKKLREEIKELEAQLRDHKPGADEINKLL 467
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
646-880 1.51e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.40  E-value: 1.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  646 KEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhlVEMEDTLNKLQEAEikvKELDVLQAKCNEQTKLIGSLTQQIRAS 725
Cdd:COG3206    182 EQLPELRKEL----EEAEAALEEFRQKNGLVDLS--EEAKLLLQQLSELE---SQLAEARAELAEAEARLAALRAQLGSG 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  726 EEKLLDLAALQkansegklEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLdleknlSAVNQVKDSL 805
Cdd:COG3206    253 PDALPELLQSP--------VIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------QEAQRILASL 318

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622  806 EKELQLLKEKftsaVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKE-REEREQQLTEAKV 880
Cdd:COG3206    319 EAELEALQAR----EASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEaRLAEALTVGNVRV 390
PRK01156 PRK01156
chromosome segregation protein; Provisional
 368-891 1.63e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.29  E-value: 1.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  368 EVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADR--EKVELLNQLEEEKRKVE-DLQFRVEEESITKG 444
Cdd:PRK01156   198 ELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNElsSLEDMKNRYESEIKTAEsDLSMELEKNNYYKE 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  445 DLERKRQIsedpENVATVSEKSRIME---LERDLALRVKEVAELRGRLESskhIDDVDTSLSLLQEISSLQEKMAAAGKE 521
Cdd:PRK01156   278 LEERHMKI----INDPVYKNRNYINDyfkYKNDIENKKQILSNIDAEINK---YHAIIKKLSVLQKDYNDYIKKKSRYDD 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  522 HQREMSSLKEkFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESaIASHQQAMEELKVSF 601
Cdd:PRK01156   351 LNNQILELEG-YEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNE-INVKLQDISSKVSSL 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  602 NKGVGAQTAEFAELKTQME---------------------KVKLDYENEMSNLKLK---QENEKSQHLKEIEALKAKLLE 657
Cdd:PRK01156   429 NQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnHIINHYNEKKSRLEEKireIEIEVKDIDEKIVDLKKRKEY 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  658 VTEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQEAEIKVKELDVlQAKCNEQTKLIGSLTQQIRA-SEEKLLDLAALQ 736
Cdd:PRK01156   509 LESEEINKSINEYNKIESARAD-LEDIKIKINELKDKHDKYEEIKN-RYKSLKLEDLDSKRTSWLNAlAVISLIDIETNR 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  737 KANSEgkleiqkLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQgKEQKLLDLEKNLSavnQVKDSLEKELQLLKEKF 816
Cdd:PRK01156   587 SRSNE-------IKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIE-NEANNLNNKYNEI---QENKILIEKLRGKIDNY 655

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622  817 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMK 891
Cdd:PRK01156   656 KKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 760-1447 1.90e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  760 IQNLETEKVGGSSKVSNLTKE--LQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKL 837
Cdd:pfam12128  148 IQNDRTLLGRERVELRSLARQfaLCDSESPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWI 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  838 NQKEEQFALMSSELEQLKsnltvMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ- 916
Cdd:pfam12128  228 RDIQAIAGIMKIRPEFTK-----LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEk 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 ---IQLELTKANEKAVQLQKNVEQTAQKAEQSQQ---ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETS 990
Cdd:pfam12128  303 rdeLNGELSAADAAVAKDRSELEALEDQHGAFLDadiETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRS 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  991 EMITKHDADIKGFKQNLLDA-EEALKAAQKKNDELETQAEELKKQAEQAKSLSSV----LASARKEIELMSDKMRDLISE 1065
Cdd:pfam12128  383 KIKEQNNRDIAGIKDKLAKIrEARDRQLAVAEDDLQALESELREQLEAGKLEFNEeeyrLKSRLGELKLRLNQATATPEL 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1066 KETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALIS---- 1141
Cdd:pfam12128  463 LLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHflrk 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1142 -------EKSKLLSEIETAQADLlkITQENDALRSSESTLL------------------QQLK-ELQANKDAVDVACQKH 1195
Cdd:pfam12128  543 eapdweqSIGKVISPELLHRTDL--DPEVWDGSVGGELNLYgvkldlkridvpewaaseEELReRLDKAEEALQSAREKQ 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1196 IKEREELEHYQKLLEENDRvikDKDDVIQRLQSSYDDLAR----NQRELLQEVSILTAERDSAQEKDLDLKSTHIALKNE 1271
Cdd:pfam12128  621 AAAEEQLVQANGELEKASR---EETFARTALKNARLDLRRlfdeKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKK 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1272 IDCLLQTNRSLQSEKEM-----LLKSREELCVSLA----NTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASL 1342
Cdd:pfam12128  698 HQAWLEEQKEQKREARTekqayWQVVEGALDAQLAllkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1343 SSLSNFLEEMKSSREASNSEKIhLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAvlaetafteKINELNLEKE 1422
Cdd:pfam12128  778 RTLERKIERIAVRRQEVLRYFD-WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADT---------KLRRAKLEME 847

                          730       740
                   ....*....|....*....|....*
gi 2024359622 1423 SVFSKSLQFEKhNEALLREKDELER 1447
Cdd:pfam12128  848 RKASEKQQVRL-SENLRGLRCEMSK 871
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 938-1183 1.98e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 49.44  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  938 TAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeketsemITKHDADIKGFKQNLLDAEEALKAA 1017
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE--------LEALQAEIDKLQAEIAEAEAEIEER 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1018 QkknDELETQAEELKKQAEQAKSLSSVLASA--------RKEIELMSDKMRDLISEketLAQERNTLKLEKESLlsqhle 1089
Cdd:COG3883     85 R---EELGERARALYRSGGSVSYLDVLLGSEsfsdfldrLSALSKIADADADLLEE---LKADKAELEAKKAEL------ 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1090 meskillvQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1169
Cdd:COG3883    153 --------EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAA 224

                          250
                   ....*....|....
gi 2024359622 1170 SESTLLQQLKELQA 1183
Cdd:COG3883    225 AAAAAAAAAAAAAA 238
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
347-495 2.03e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.86  E-value: 2.03e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  347 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAAD 412
Cdd:COG2433    347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  413 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdlERKRQISEDPEnvaTVSEKSRIMELERDLALRVKEVAELRGRLESS 492
Cdd:COG2433    427 AEVEELEAELEEKDERIERLERELSEARS-----EERREIRKDRE---ISRLDREIERLERELEEERERIEELKRKLERL 498


                   ...
gi 2024359622  493 KHI 495
Cdd:COG2433    499 KEL 501
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1952-2082 2.23e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.47  E-value: 2.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1952 KEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASaktlqsvvktLESDKLKLEEKVKNLEQKLK-AKSEQ 2030
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEE----------LEAELEEKDERIERLERELSeARSEE 457

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 2024359622 2031 PltvtspsgdiaANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRM 2082
Cdd:COG2433    458 R-----------REIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 631-879 3.49e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  631 SNLKLKQENEKSQHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQhLVEMEDTLNKLQeaeikvKELDVLQAKCNE 710
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKEL----AALKKEEKALLKQLAALERR-IAALARRIRALE------QELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  711 QTKLIGSLTQQIRASEEKLLD-LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggSSKVSNLTKELQGKEQKLL 789
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAElLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYL----APARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  790 DLEKNLSAVNQVKDSLEKELQLLKEKFtsavdgaENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKERE 869
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAAL-------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                          250
                   ....*....|
gi 2024359622  870 EREQQLTEAK 879
Cdd:COG4942    237 AAAAERTPAA 246
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1516-2030 3.66e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 3.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1516 SDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKEN---LTVEKKARILD 1592
Cdd:pfam05483  281 DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAhsfVVTEFEATTCS 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1593 KESFL-LERMELQNNIGFLEKEVEEMREKNKEfLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFT 1671
Cdd:pfam05483  361 LEELLrTEQQRLEKNEDQLKIITMELQKKSSE-LEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQ 439

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1672 SLS----VSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQE---NESLHAEWKSLVIINEEILKEKEKLSKEYYKLH 1744
Cdd:pfam05483  440 ELIfllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEklkNIELTAHCDKLLLENKELTQEASDMTLELKKHQ 519

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1745 EKVVALLEQTDAdfscrllvsegkhellleemsnlalKLREIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDaihqe 1824
Cdd:pfam05483  520 EDIINCKKQEER-------------------------MLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLD----- 569

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1825 KIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnlENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1904
Cdd:pfam05483  570 KSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN---------KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNK 640

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1905 LAEELGRSRDE----VTSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEIDEErasLQKSISDTSALITQKDEELE 1980
Cdd:pfam05483  641 LELELASAKQKfeeiIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKR---CQHKIAEMVALMEKHKHQYD 717

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1981 KLRNEITVLRGENASAKTLQSVVK-TLESDKLKLEEKVKNLEQKLKAKSEQ 2030
Cdd:pfam05483  718 KIIEERDSELGLYKNKEQEQSSAKaALEIELSNIKAELLSLKKQLEIEKEE 768
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1022-1594 4.38e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 4.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1022 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1101
Cdd:PRK01156   176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYE 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1102 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVA---LISEKSKLLSEIEtaqaDLLKITQENDALRSSESTLLQQL 1178
Cdd:PRK01156   256 SEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKnrnYINDYFKYKNDIE----NKKQILSNIDAEINKYHAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1179 KELQANKDAVdvacQKHIKEREELEH-----------YQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSIL 1247
Cdd:PRK01156   332 SVLQKDYNDY----IKKKSRYDDLNNqilelegyemdYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAI 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1248 TAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSEKEMLlkSREELCVSLANTANENQALKLRKD--EMQTELETER 1325
Cdd:PRK01156   408 KKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEML--NGQSVCPVCGTTLGEEKSNHIINHynEKKSRLEEKI 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1326 EKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQEAL--FASEQRLLAER----EELVNENKAVTEKLTKA 1399
Cdd:PRK01156   486 REIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLedIKIKINELKDKhdkyEEIKNRYKSLKLEDLDS 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1400 TADAVLAETAFTEKINELNLEKesvfskslQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELdFSAKRL 1479
Cdd:PRK01156   566 KRTSWLNALAVISLIDIETNRS--------RSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANN-LNNKYN 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1480 LVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILN- 1558
Cdd:PRK01156   637 EIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSd 716

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 2024359622 1559 -----RERTELQDKCQKLTGEVENMKENLTVEKKARILDKE 1594
Cdd:PRK01156   717 rindiNETLESMKKIKKAIGDLKRLREAFDKSGVPAMIRKS 757
PRK01156 PRK01156
chromosome segregation protein; Provisional
 463-1065 4.81e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 4.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  463 SEKSRIMELERDLALRVKEVAELrgrlesSKHIDDVDTSLS-LLQEISSLQEKMAAAGKEHQ------REMSSLKEKFES 535
Cdd:PRK01156   180 AEISNIDYLEEKLKSSNLELENI------KKQIADDEKSHSiTLKEIERLSIEYNNAMDDYNnlksalNELSSLEDMKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  536 SEEALRKEIKTLSASNERMGK----ENESLKTKLDHANKENSDVIELWKSKleSAIASHQQAMEELKVSFNK--GVGAQT 609
Cdd:PRK01156   254 YESEIKTAESDLSMELEKNNYykelEERHMKIINDPVYKNRNYINDYFKYK--NDIENKKQILSNIDAEINKyhAIIKKL 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  610 AEFAELKTQMEKVKLDYE---NEMSNLKLKQENEKSqHLKEIEALKAKLlevtEEKEQTLENLKAKLESVEDQHLVEmed 686
Cdd:PRK01156   332 SVLQKDYNDYIKKKSRYDdlnNQILELEGYEMDYNS-YLKSIESLKKKI----EEYSKNIERMSAFISEILKIQEID--- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  687 tlnklqeAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAA-LQKANSEGKLEIQKLSEQLQAAEKQIQNLET 765
Cdd:PRK01156   404 -------PDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRnMEMLNGQSVCPVCGTTLGEEKSNHIINHYNE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  766 EKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVK-DSLEKELQLLKEKFTSAVDgAENAQRAMQETINKLNQKEEQF 844
Cdd:PRK01156   477 KKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLED-IKIKINELKDKHDKYEEIKNRY 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  845 AlmSSELEQLKSNLTV------------METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKER 912
Cdd:PRK01156   556 K--SLKLEDLDSKRTSwlnalavislidIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  913 QLEQIQlELTKANEKavqLQKNVEQtaqkaeqsqqetLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEM 992
Cdd:PRK01156   634 KYNEIQ-ENKILIEK---LRGKIDN------------YKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANR 697

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622  993 ITKhDADIKGFKQNLLDAEEALKAAQKKNDELET--QAEELKKQAEQAKSLSSVLASARKEI-ELMSDKMRDLISE 1065
Cdd:PRK01156   698 ARL-ESTIEILRTRINELSDRINDINETLESMKKikKAIGDLKRLREAFDKSGVPAMIRKSAsQAMTSLTRKYLFE 772
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
751-1053 4.85e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  751 EQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLlkekftsavdgaenaqRAM 830
Cdd:COG4913    610 AKLAALEAELAELEEE-------LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDV----------------ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  831 QETINKLNQKEEQFALMSSELEQLKSnltvmetKLKEREEREQQLTEAKVKLENDIAEImkssgdssaqlmkmndelrlk 910
Cdd:COG4913    667 EREIAELEAELERLDASSDDLAALEE-------QLEELEAELEELEEELDELKGEIGRL--------------------- 718

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  911 ERQLEQIQLELTkanekavQLQKNVEQTAQKAEQSQQETLKTHQEELKKmQDQLTDMKKQMETSQNQYKDLQAKYEKETS 990
Cdd:COG4913    719 EKELEQAEEELD-------ELQDRLEAAEDLARLELRALLEERFAAALG-DAVERELRENLEERIDALRARLNRAEEELE 790

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359622  991 EMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQ---------AEELKKQAEQAKS-LSSVLASARKEIE 1053
Cdd:COG4913    791 RAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDglpeyeerfKELLNENSIEFVAdLLSKLRRAIREIK 863
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
661-1256 5.42e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 5.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  661 EKEQTLENLKAKLESVEDqhLVEMEDTLNKLQEaeiKVKELDVLQAKCNEQTKLIGSLTQQIRasEEKLLDLAALQKANS 740
Cdd:COG4913    219 EEPDTFEAADALVEHFDD--LERAHEALEDARE---QIELLEPIRELAERYAAARERLAELEY--LRAALRLWFAQRRLE 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  741 EGKLEIQKLSEQLQAAEKQIQNLETEKVG---------------GSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSL 805
Cdd:COG4913    292 LLEAELEELRAELARLEAELERLEARLDAlreeldeleaqirgnGGDRLEQLEREIERLERELEERERRRARLEALLAAL 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  806 -------EKELQLLKEKFTSAVDGAENAQRAMQ----ETINKLNQKEEQFALMSSELEQL---KSNLTVMETKLKEREER 871
Cdd:COG4913    372 glplpasAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALAE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  872 EQQLTEAKVKLendIAEIMKSSGDSS------------------------AQLMKMNDELRLKERqleqIQLELTKANEK 927
Cdd:COG4913    452 ALGLDEAELPF---VGELIEVRPEEErwrgaiervlggfaltllvppehyAAALRWVNRLHLRGR----LVYERVRTGLP 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  928 AVQLQKNVEQT-AQKAEqsqqetLKTH------QEELKKM--------QDQLTDMKKQMeTSQNQYKDLQAKYEKETSEM 992
Cdd:COG4913    525 DPERPRLDPDSlAGKLD------FKPHpfrawlEAELGRRfdyvcvdsPEELRRHPRAI-TRAGQVKGNGTRHEKDDRRR 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  993 ITKH-------DADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSV------LASARKEIELMSDKM 1059
Cdd:COG4913    598 IRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswdeidVASAEREIAELEAEL 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1060 RDLISEKETLAQerntLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTekvAL 1139
Cdd:COG4913    678 ERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR---AL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1140 ISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQL-KELQANKDAVDVACQKHIKEREELEHYQKLLE--ENDRVI 1216
Cdd:COG4913    751 LEERFAAALGDAVERELRENLEERIDALRARLNRAEEELeRAMRAFNREWPAETADLDADLESLPEYLALLDrlEEDGLP 830

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|
gi 2024359622 1217 KDKDDVIQRLQSSyddlarNQRELLQEVSILTAERDSAQE 1256
Cdd:COG4913    831 EYEERFKELLNEN------SIEFVADLLSKLRRAIREIKE 864
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 792-1048 6.96e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.52  E-value: 6.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  792 EKNLSAVNQVKDSLEKELQLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREER 871
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAE-------LDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  872 -EQQLTEAKVK-LENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQSQQEt 949
Cdd:COG3883     88 lGERARALYRSgGSVSYLDVLLGSESFSDFLDRLSALSKIADADADLLE-ELKADKAELEAKKAELEAKLAELEALKAE- 165

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  950 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAE 1029
Cdd:COG3883    166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAS 245

                          250
                   ....*....|....*....
gi 2024359622 1030 ELKKQAEQAKSLSSVLASA 1048
Cdd:COG3883    246 AAGAGAAGAAGAAAGSAGA 264
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 607-845 7.56e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  607 AQTAEFAELKTQMEKVKldyenemsnlklKQENEKSQHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQhLVEMED 686
Cdd:COG4942     17 AQADAAAEAEAELEQLQ------------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEA 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  687 TLNKLQeaeikvKELDVLQAKCNEQTKLIGSLTQQI----RASEEKLL-----------DLAALQKANSEGKLEIQKLSE 751
Cdd:COG4942     84 ELAELE------KEIAELRAELEAQKEELAELLRALyrlgRQPPLALLlspedfldavrRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  752 QLQAAEKQIQNLETEKvggsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsAVDGAENAQRAMQ 831
Cdd:COG4942    158 DLAELAALRAELEAER-------AELEALLAELEEERAALEALKAERQKLLARLEKELAELAA----ELAELQQEAEELE 226

                          250
                   ....*....|....
gi 2024359622  832 ETINKLNQKEEQFA 845
Cdd:COG4942    227 ALIARLEAEAAAAA 240
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 704-1076 8.04e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 47.87  E-value: 8.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  704 LQAKCNEQTKLIGSlTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvSNLTKELQG 783
Cdd:PRK10246   225 LQVLTDEEKQLLTA-QQQQQQSLNWLTRLDELQQEASRRQQALQQALAAEEKAQPQLAALSL---------AQPARQLRP 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  784 KEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQ---KEEQFALMSSELEQLKSNLTV 860
Cdd:PRK10246   295 HWERIQEQSAALAHTRQQIEEVNTRLQSTMALRARIRHHAAKQSAELQAQQQSLNTwlaEHDRFRQWNNELAGWRAQFSQ 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  861 METKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMkmndELRLKERQLEQiqlELTKANEKAVQLQKNVEQTaq 940
Cdd:PRK10246   375 QTSDREQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAAL----AQHAEQRPLRQ---RLVALHGQIVPQQKRLAQL-- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  941 kaeqsqQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKEtsEMItkhdADIKGFKQNL------------- 1007
Cdd:PRK10246   446 ------QVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQE--ARI----KDLEAQRAQLqagqpcplcgsts 513

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622 1008 ---LDAEEALK--AAQKKNDELEtqaEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTL 1076
Cdd:PRK10246   514 hpaVEAYQALEpgVNQSRLDALE---KEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAV 584
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 741-1134 8.16e-05

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 47.64  E-value: 8.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  741 EGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKE--QKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 818
Cdd:COG5185    189 LKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEalKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLE 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  819 AVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETK------LKEREEREQQLTEAKVKLENDIAEIMKS 892
Cdd:COG5185    269 KLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLeeqlaaAEAEQELEESKRETETGIQNLTAEIEQG 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  893 SGDSSAQLMKMNDE---------LRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQ 963
Cdd:COG5185    349 QESLTENLEAIKEEienivgeveLSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQ 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  964 LTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKgfkqnlldaeealKAAQKKNDELETQAEELKKQAEQAKS-LS 1042
Cdd:COG5185    429 IEQATSSNEEVSKLLNELISELNKVMREADEESQSRLE-------------EAYDEINRSVRSKKEDLNEELTQIESrVS 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1043 SVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQK 1122
Cdd:COG5185    496 TLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANLRTAVIDELTQ 575

                          410
                   ....*....|..
gi 2024359622 1123 EAAEAKSRQEST 1134
Cdd:COG5185    576 YLSTIESQQARE 587
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 520-676 8.24e-05

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 47.71  E-value: 8.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  520 KEHQREMSSLKEKFE---SSEEALRKEIKTLSASNERM---GKENESLKTKLDHANKENSDVIELWK------SKLESAI 587
Cdd:pfam05667  331 QQREEELEELQEQLEdleSSIQELEKEIKKLESSIKQVeeeLEELKEQNEELEKQYKVKKKTLDLLPdaeeniAKLQALV 410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  588 ASHQQAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyenemsnlKLKQENEKSQHLKEIEALKAKLLEVTEE---KEQ 664
Cdd:pfam05667  411 DASAQRLVELAGQWEKHRVPLIEEYRALKEA---------------KSNKEDESQRKLEEIKELREKIKEVAEEakqKEE 475

                          170
                   ....*....|..
gi 2024359622  665 TLENLKAKLESV 676
Cdd:pfam05667  476 LYKQLVAEYERL 487
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1009-1369 8.36e-05

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 47.58  E-value: 8.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1009 DAEEALKAAQKKNDELETQAEELKKQAEQAKSlssVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1088
Cdd:pfam07888   56 QREKEKERYKRDREQWERQRRELESRVAELKE---ELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIR 132

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1089 EMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALR 1168
Cdd:pfam07888  133 ELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQ 212

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1169 SSESTLLQQLKELQANKDAVDVACqkhikerEELEHYQKLLEENDRVIKDKDDVIQRLQSSYDdlaRNQRELLQevsilt 1248
Cdd:pfam07888  213 DTITTLTQKLTTAHRKEAENEALL-------EELRSLQERLNASERKVEGLGEELSSMAAQRD---RTQAELHQ------ 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1249 aERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQS----EKEMLLKSREELcvslantanenqalkLRKDEMQTELETE 1324
Cdd:pfam07888  277 -ARLQAAQLTLQLADASLALREGRARWAQERETLQQsaeaDKDRIEKLSAEL---------------QRLEERLQEERME 340

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359622 1325 REKLE-KMTKDNMDLKASLSSLSNFLEEMKSSREASNSEKIHLLQE 1369
Cdd:pfam07888  341 REKLEvELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAE 386
PTZ00121 PTZ00121
MAEBL; Provisional
 1017-1875 8.62e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 8.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKIll 1096
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA-- 1160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1097 vqqdreelwtkneelnSENKKILKQKEAAEAKSRQESTEkvaliSEKSKLLSEIETAQadllKITQENDALRSSESTLLQ 1176
Cdd:PTZ00121  1161 ----------------EDARKAEEARKAEDAKKAEAARK-----AEEVRKAEELRKAE----DARKAEAARKAEEERKAE 1215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1177 QLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQE 1256
Cdd:PTZ00121  1216 EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEA 1295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1257 KDLDLKSTHIALKNEIDCLLQTNRsLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNM 1336
Cdd:PTZ00121  1296 KKAEEKKKADEAKKKAEEAKKADE-AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1337 DLKASLSSLSNFLEEMKSSREASN--SEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAftEKI 1414
Cdd:PTZ00121  1375 EAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA--KKK 1452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1415 NELNLEKESVFSKSLQFEKHNEAllREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIEAL 1494
Cdd:PTZ00121  1453 AEEAKKAEEAKKKAEEAKKADEA--KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1495 EEELKKKNLENQEliacRSDLSDLLKEAQDARRTLENELAavsHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGE 1574
Cdd:PTZ00121  1531 EEAKKADEAKKAE----EKKKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEE 1603

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1575 VENMK-ENLTVEKKARIldKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILY 1653
Cdd:PTZ00121  1604 EKKMKaEEAKKAEEAKI--KAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK 1681

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1654 KETEQLASKIEQLKSDFTSL----SVSKAELEDVHSCVSVMLDELQHKYEVTE--KEKMELVQENESLHAEWKSLVIInE 1727
Cdd:PTZ00121  1682 KAEEDEKKAAEALKKEAEEAkkaeELKKKEAEEKKKAEELKKAEEENKIKAEEakKEAEEDKKKAEEAKKDEEEKKKI-A 1760

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1728 EILKEKEKLSKEYYKLHEKVVAllEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQTFMQKFEADKRAEEV 1807
Cdd:PTZ00121  1761 HLKKEEEKKAEEIRKEKEAVIE--EELDEEDEKRRMEVDKKIK---DIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEV 1835

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622 1808 LQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQnnlkNEEELTKSKELLNLENKKVE 1875
Cdd:PTZ00121  1836 ADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKED----DEEEIEEADEIEKIDKDDIE 1899
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1799-1997 8.68e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1799 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELK 1878
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1879 KEFEALkLAAAQKSQQ----------------------LAALQEENVKLAEELGRSRDEVTS-HQKLEEERSVLNNQLLE 1935
Cdd:COG4942    104 EELAEL-LRALYRLGRqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAAlRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622 1936 MKKSLpsntLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAK 1997
Cdd:COG4942    183 LEEER----AALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 853-1523 9.69e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.79  E-value: 9.69e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  853 QLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAE---IMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAV 929
Cdd:pfam05483  107 KLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQEnkdLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  930 QLQKNVEQTAQKAEQSQQETLKTHQEelkkMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLD 1009
Cdd:pfam05483  187 DLNNNIEKMILAFEELRVQAENARLE----MHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1010 AEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLE 1089
Cdd:pfam05483  263 LEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNK 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1090 MESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRS 1169
Cdd:pfam05483  343 AKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1170 SESTLLQQLKELQANKDAVDVACQKHIKEREELE-----------HYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQR 1238
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEiqltaiktseeHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENK 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1239 ELLQEVSILTAERDSAQEKDLDLKSTHIALKNEIDCLLQTNRSLQSE----KEMLLKSREELCVSLANTANENQALKLRK 1314
Cdd:pfam05483  503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1315 DEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREASNSE------KIHLLQEALFASEQRLlaerEELVNE 1388
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeiKVNKLELELASAKQKF----EEIIDN 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1389 NKAVTEkLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEALLREKDelERKYSELLDEKKSLENAFSDMKR 1468
Cdd:pfam05483  659 YQKEIE-DKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKH--KHQYDKIIEERDSELGLYKNKEQ 735

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1469 EQEldfSAKRLLVQENTTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQ 1523
Cdd:pfam05483  736 EQS---SAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 344-1417 9.96e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.74  E-value: 9.96e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  344 LQEALKEKQQHIEQLLAERDLERAEVAKATSHV-GEIEQELALVRDGhdrhvlEMEAKMDQLRAMVEAADREKVEllnql 422
Cdd:TIGR01612  625 LKKIIENNNAYIDELAKISPYQVPEHLKNKDKIySTIKSELSKIYED------DIDALYNELSSIVKENAIDNTE----- 693

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 eeEKRKVEDLQFRVEEESITKGDLERKRQIS-----EDPEN--VATVSEKSRIM--ELERDLALRVKEVAELRGRLES-- 491
Cdd:TIGR01612  694 --DKAKLDDLKSKIDKEYDKIQNMETATVELhlsniENKKNelLDIIVEIKKHIhgEINKDLNKILEDFKNKEKELSNki 771

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  492 ---SKHIDDVDTSLSLLQEISSLQEKMAAAGKEHQREMsslKEKFESSEEALR----KEIKTLSASNERMGKENESLKTK 564
Cdd:TIGR01612  772 ndyAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDA---KQNYDKSKEYIKtisiKEDEIFKIINEMKFMKDDFLNKV 848

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  565 LDHANKENSDvielwKSKLESAIASHQQAMEELKVSF-NKGVGAQTAEFAELKTQMEKVKLDYENEMSNLK-LKQENEks 642
Cdd:TIGR01612  849 DKFINFENNC-----KEKIDSEHEQFAELTNKIKAEIsDDKLNDYEKKFNDSKSLINEINKSIEEEYQNINtLKKVDE-- 921

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  643 qHLKEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVE------MEDTL-NKLQEAEIKVKELDV--LQAKCNEQTK 713
Cdd:TIGR01612  922 -YIKICENTKESIEKFHNKQNILKEILNKNIDTIKESNLIEksykdkFDNTLiDKINELDKAFKDASLndYEAKNNELIK 1000

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  714 LIGSLTQQIRASEEKLldlaaLQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLD--- 790
Cdd:TIGR01612 1001 YFNDLKANLGKNKENM-----LYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIELLNkei 1075

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  791 ---LEKNLSAVNQVKDSLE--KELQLLKE---KFTSAV----DGAENAQRAMQETINKL----NQKEEQFALMSSELEQL 854
Cdd:TIGR01612 1076 leeAEINITNFNEIKEKLKhyNFDDFGKEeniKYADEInkikDDIKNLDQKIDHHIKALeeikKKSENYIDEIKAQINDL 1155

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  855 K--SNLTVMETKLKEREEREQQLT----------EAKVKLENDIAEIMKSSGD-SSAQLMKMNDELRLKERQLEQIQLEL 921
Cdd:TIGR01612 1156 EdvADKAISNDDPEEIEKKIENIVtkidkkkniyDEIKKLLNEIAEIEKDKTSlEEVKGINLSYGKNLGKLFLEKIDEEK 1235

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  922 TKANEKAVQLQKNVEQTAQKAEQSQqetlkthqeELKKMQDQLTDMKKQMET---SQNQYKD---LQAKYEKETSEMITK 995
Cdd:TIGR01612 1236 KKSEHMIKAMEAYIEDLDEIKEKSP---------EIENEMGIEMDIKAEMETfniSHDDDKDhhiISKKHDENISDIREK 1306

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  996 HDADIKGF--KQNLLDAEEALKA----AQKKNDELETQAEELKK-----QAEQAKSLSSVLASARKEIELMSDKMRDLIS 1064
Cdd:TIGR01612 1307 SLKIIEDFseESDINDIKKELQKnlldAQKHNSDINLYLNEIANiynilKLNKIKKIIDEVKEYTKEIEENNKNIKDELD 1386

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1065 EKETLAQerntlKLEKESLLSqhlEMESKI--LLVQQDREELWTKNEELNSEnkkILKQKEAAEA--KSRQESTEKVALi 1140
Cdd:TIGR01612 1387 KSEKLIK-----KIKDDINLE---ECKSKIesTLDDKDIDECIKKIKELKNH---ILSEESNIDTyfKNADENNENVLL- 1454

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1141 sekskLLSEIETAQAD---LLKITQENdalrsSESTLLQQLKELQANKDavdvacqKHIKEREELEHYQKLLEENDRVIK 1217
Cdd:TIGR01612 1455 -----LFKNIEMADNKsqhILKIKKDN-----ATNDHDFNINELKEHID-------KSKGCKDEADKNAKAIEKNKELFE 1517

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1218 D-KDDVIQRLQSSYDDLARNQrellqevsILTAERDSAQEKDlDLKSthiaLKNEIdcLLQTNRSLQSEKEMllkSREEL 1296
Cdd:TIGR01612 1518 QyKKDVTELLNKYSALAIKNK--------FAKTKKDSEIIIK-EIKD----AHKKF--ILEAEKSEQKIKEI---KKEKF 1579

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1297 CVSlANTANENQALKLRKDeMQTELETEREKLEKMT----------KDNMDLKASLSSLSNFLEEMKSSREASNSEKIHL 1366
Cdd:TIGR01612 1580 RIE-DDAAKNDKSNKAAID-IQLSLENFENKFLKISdikkkindclKETESIEKKISSFSIDSQDTELKENGDNLNSLQE 1657

                         1130      1140      1150      1160      1170
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1367 LQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINEL 1417
Cdd:TIGR01612 1658 FLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEI 1708
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 745-1049 1.08e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  745 EIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGkeqklldLEKNLSAVNQVKD-SLEKELQLLKEKftsaVDGA 823
Cdd:COG3096    837 ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQL-------LNKLLPQANLLADeTLADRLEELREE----LDAA 905

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  824 ENAQRAMQETINKLNQKEEQFALMSSELEQLKsNLTVMETKLKEREEREQQLTEAkvklendIAEIMK-----SSGDSSA 898
Cdd:COG3096    906 QEAQAFIQQHGKALAQLEPLVAVLQSDPEQFE-QLQADYLQAKEQQRRLKQQIFA-------LSEVVQrrphfSYEDAVG 977

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  899 QLMK---MNDELRlkeRQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQ 975
Cdd:COG3096    978 LLGEnsdLNEKLR---ARLEQAEEARREAREQLRQAQAQYSQ-YNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEA 1053

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622  976 NQykdlQAKYEK-ETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAK-SLSSVLASAR 1049
Cdd:COG3096   1054 EE----RARIRRdELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKaGWCAVLRLAR 1125
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 820-1183 1.12e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.64  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  820 VDGAENAQRAMQETINKLNQKEEQFALMSSELEQLksnltvmetklkerEEREQQLTEakvklENDIAeimkssgdsSAQ 899
Cdd:COG3096    284 SERALELRRELFGARRQLAEEQYRLVEMARELEEL--------------SARESDLEQ-----DYQAA---------SDH 335

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  900 LMKMNDELRLKERqLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQN--- 976
Cdd:COG3096    336 LNLVQTALRQQEK-IERYQEDLEELTERLEEQEEVVEE-AAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTrai 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  977 QYKD-LQAKYEKE--------TSEMITKHDADIK-----------GFKQNLLDA-------EEALKAAQKKNDELET--- 1026
Cdd:COG3096    414 QYQQaVQALEKARalcglpdlTPENAEDYLAAFRakeqqateevlELEQKLSVAdaarrqfEKAYELVCKIAGEVERsqa 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1027 ---------QAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDL----------ISEKETLAQERNTLKLEKESLLSQH 1087
Cdd:COG3096    494 wqtarellrRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLeefcqrigqqLDAAEELEELLAELEAQLEELEEQA 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1088 LEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEaKSRQESTEKVAlisEKSKLLSEIETAQADLLKITQENDAL 1167
Cdd:COG3096    574 AEAVEQRSELRQQLEQLRARIKELAARAPAWLAAQDALE-RLREQSGEALA---DSQEVTAAMQQLLEREREATVERDEL 649

                          410
                   ....*....|....*.
gi 2024359622 1168 RSSESTLLQQLKELQA 1183
Cdd:COG3096    650 AARKQALESQIERLSQ 665
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1097-1527 1.19e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1097 VQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSES--TL 1174
Cdd:COG4717     51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPL 130

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1175 LQQLKELQANKDAVDVACQKHIKEREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQ-RELLQEVSILTAERDS 1253
Cdd:COG4717    131 YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAE 210

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1254 AQEKDLDLKSTHIALKNEIDCLLQTNRSLQ-----SEKEMLLKSREELCVSLANTAN----------------------- 1305
Cdd:COG4717    211 LEEELEEAQEELEELEEELEQLENELEAAAleerlKEARLLLLIAAALLALLGLGGSllsliltiagvlflvlgllallf 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1306 ---ENQALKLRKDEMQTELETEREKLEK------MTKDNMDLKASLSSLSNFLEEMKSSREAsNSEKIHLLQEALfasEQ 1376
Cdd:COG4717    291 lllAREKASLGKEAEELQALPALEELEEeeleelLAALGLPPDLSPEELLELLDRIEELQEL-LREAEELEEELQ---LE 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1377 RLLAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQF-EKHNEALLREK--------DELER 1447
Cdd:COG4717    367 ELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELlEALDEEELEEEleeleeelEELEE 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1448 KYSELLDEKKSLENAFSDMKREQELDfsakrllvqentTLKYSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARR 1527
Cdd:COG4717    447 ELEELREELAELEAELEQLEEDGELA------------ELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
46 PHA02562
endonuclease subunit; Provisional
 727-1032 1.20e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  727 EKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETekvggsskvsnltkelQGKEQKllDLEKNLSAVNQVkdsle 806
Cdd:PHA02562   157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQ----------------QIKTYN--KNIEEQRKKNGE----- 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  807 kELQLLKEKFTSAVDGAENAqramqetinklnqkeeqfalmSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDI 886
Cdd:PHA02562   214 -NIARKQNKYDELVEEAKTI---------------------KAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKI 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  887 AEIMKssgdssaqLMKM---NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQ--TAQKAEQSQQETLKTHQEELKKMQ 961
Cdd:PHA02562   272 EQFQK--------VIKMyekGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKldTAIDELEEIMDEFNEQSKKLLELK 343

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622  962 DQLTDMKKQMETSQNQYKDLQAKYEKETSEMITkHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELK 1032
Cdd:PHA02562   344 NKISTNKQSLITLVDKAKKVKAAIEELQAEFVD-NAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLK 413
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 862-1053 1.22e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 46.75  E-value: 1.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  862 ETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQK 941
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  942 AEQSQQ--------------ETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMitkhdadikgfKQNL 1007
Cdd:COG3883     95 LYRSGGsvsyldvllgsesfSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAEL-----------EALK 163

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359622 1008 LDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIE 1053
Cdd:COG3883    164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAE 209
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1491-2027 1.46e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 47.20  E-value: 1.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1491 IEALEEELKKKNLE----NQELIACRSDLSDLLKEAQDarrtLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQD 1566
Cdd:PRK01156   185 IDYLEEKLKSSNLEleniKKQIADDEKSHSITLKEIER----LSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKT 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1567 KCQKLTGEVENMKENLTVEKkarildkesfllERMELQNNigflekEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVI 1646
Cdd:PRK01156   261 AESDLSMELEKNNYYKELEE------------RHMKIIND------PVYKNRNYINDYFKYKNDIENKKQILSNIDAEIN 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1647 KEKMILYK--ETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVI 1724
Cdd:PRK01156   323 KYHAIIKKlsVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1725 INEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHEL------------LLEEMSNLALKL--REIERLQ 1790
Cdd:PRK01156   403 DPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttLGEEKSNHIINHynEKKSRLE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1791 AQTFMQKFEADKRAEEVLQtmekVTKEKDAIHQEKIETLAS----LENSRQTNEKLQNELDMLKQNNLKNEE--ELTKSK 1864
Cdd:PRK01156   483 EKIREIEIEVKDIDEKIVD----LKKRKEYLESEEINKSINeynkIESARADLEDIKIKINELKDKHDKYEEikNRYKSL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1865 ELLNLENKKVEELKK-------EFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEM 1936
Cdd:PRK01156   559 KLEDLDSKRTSWLNAlavisliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENEANNLNNKYNEI 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1937 K-KSLPSNTLREST--LKKEIdEERASLQKSISDTSALITQKDEELEKLRNEitvLRGENASAKTLQSVVKTLESDKLKL 2013
Cdd:PRK01156   639 QeNKILIEKLRGKIdnYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINEL 714

                          570
                   ....*....|....
gi 2024359622 2014 EEKVKNLEQKLKAK 2027
Cdd:PRK01156   715 SDRINDINETLESM 728
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1779-1985 1.68e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1779 LALKLREIERLQAQtfmqKFEADKRAEEVLQTMEKVTKEKDAIHQekietLASLENSRQTNEKLQNELdmlkqnnlkneE 1858
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAELDALQERREALQR-----LAEYSWDEIDVASAEREI-----------A 671

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1859 ELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEmkk 1938
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--- 748

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359622 1939 SLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNE 1985
Cdd:COG4913    749 ALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1820-2030 1.75e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1820 AIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQ 1899
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1900 EENVKLAEELGRSRDEVTSHQKLEEERSVLNNQllemkksLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEEL 1979
Cdd:COG4942     97 AELEAQKEELAELLRALYRLGRQPPLALLLSPE-------DFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1980 EKLRNEITVLRGENASAKtlqsvvKTLESDKLKLEEKVKNLEQKLKAKSEQ 2030
Cdd:COG4942    170 EAERAELEALLAELEEER------AALEALKAERQKLLARLEKELAELAAE 214
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
343-983 1.86e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  343 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlvrdghdrHVLEMEAKMDQLRAMVEAADREKVELLNQL 422
Cdd:PRK02224   210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE--------ELETLEAEIEDLRETIAETEREREELAEEV 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 EEEKRKVEDLQfrvEEESITKGDLERKrqiSEDPENVATVSE--KSRIMELERDLALRVKEVAELRGRLES-SKHIDDVD 499
Cdd:PRK02224   282 RDLRERLEELE---EERDDLLAEAGLD---DADAEAVEARREelEDRDEELRDRLEECRVAAQAHNEEAESlREDADDLE 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  500 TslsllqEISSLQEKMAAAGKEHQREMSSLkEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELW 579
Cdd:PRK02224   356 E------RAEELREEAAELESELEEAREAV-EDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  580 KSkLESAIASHQQAMEELKVSFNKGVGAQTAefaelktqmekvkldyenemsnlklkQENEKSQHLKEIEALKAKLLEVT 659
Cdd:PRK02224   429 AE-LEATLRTARERVEEAEALLEAGKCPECG--------------------------QPVEGSPHVETIEEDRERVEELE 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEkeqtLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDvlqakcnEQTKLIGSLTQQIRASeeklldlaalqkan 739
Cdd:PRK02224   482 AE----LEDLEEEVEEVEERL-----ERAEDLVEAEDRIERLE-------ERREDLEELIAERRET-------------- 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  740 segkleIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEkftsa 819
Cdd:PRK02224   532 ------IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAA----- 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  820 vdgAENAqramQETINKLNQKEEQFALMSSELEQlksnltvmetKLKEREEREQQLTEakvKLENDIAEIMKSSGDSSaq 899
Cdd:PRK02224   601 ---IADA----EDEIERLREKREALAELNDERRE----------RLAEKRERKRELEA---EFDEARIEEAREDKERA-- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  900 lmkmndelrlkERQLEQIQLELTKANEKAVQLQKNVeqTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYK 979
Cdd:PRK02224   659 -----------EEYLEQVEEKLDELREERDDLQAEI--GAVENELEELEELRERREALENRVEALEALYDEAEELESMYG 725


                   ....
gi 2024359622  980 DLQA 983
Cdd:PRK02224   726 DLRA 729
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1109-1385 1.96e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 1.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1109 EELNSENKKILKQKEAAEAKSRQESTEKVALI--SEKSKLLSEIETAQA--DLLKITQENDALRSSESTLLQQLKELQAN 1184
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIqnAEKNILLLNQARLQAleDLEKILTEKEALQGKINILEMRLSETDAR 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1185 kdaVDVACQKHIKEREELEHYQKLLEEndrvikdkddVIQRLQSSYddlarnqrellQEVSILTAERDSAQEKDLDLKST 1264
Cdd:PLN02939   186 ---IKLAAQEKIHVEILEEQLEKLRNE----------LLIRGATEG-----------LCVHSLSKELDVLKEENMLLKDD 241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1265 HIALKNEIDCLLQTNRS---LQSEKEMLLKSREEL-CVSLANTANENQALKLRKDEMQTELETEREKLEKMTK------- 1333
Cdd:PLN02939   242 IQFLKAELIEVAETEERvfkLEKERSLLDASLRELeSKFIVAQEDVSKLSPLQYDCWWEKVENLQDLLDRATNqvekaal 321

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1334 ---DNMDLKASLSSLSNFLEEMKSSREASnsEKIHLLQEALFASEQRLLAEREEL 1385
Cdd:PLN02939   322 vldQNQDLRDKVDKLEASLKEANVSKFSS--YKVELLQQKLKLLEERLQASDHEI 374
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
610-1128 2.22e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  610 AEFAELKTQMEKVKlDYENEMSNLKLKQEneksqHLKEIEALKAKLLEVTEEKEQtLENLKAKLESVEDQhlvemedtln 689
Cdd:COG4913    225 EAADALVEHFDDLE-RAHEALEDAREQIE-----LLEPIRELAERYAAARERLAE-LEYLRAALRLWFAQ---------- 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  690 klQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAAlQKANSEGkleiqklsEQLQAAEKQIQNLETEKVG 769
Cdd:COG4913    288 --RRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA-QIRGNGG--------DRLEQLEREIERLERELEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  770 GSSKVSNLTKELQGKEQKLL----DLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFA 845
Cdd:COG4913    357 RERRRARLEALLAALGLPLPasaeEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  846 LMSSELEQ----LKSNLTVMETKLK-------------------ER------------EEREQQLTEA------------ 878
Cdd:COG4913    437 NIPARLLAlrdaLAEALGLDEAELPfvgelievrpeeerwrgaiERvlggfaltllvpPEHYAAALRWvnrlhlrgrlvy 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  879 -KVKLENDIAEIMKSSGDSSAQLMK---------MNDELRLK--------ERQLEQ----IQLE-LTKANEKAVQLQKnv 935
Cdd:COG4913    517 eRVRTGLPDPERPRLDPDSLAGKLDfkphpfrawLEAELGRRfdyvcvdsPEELRRhpraITRAgQVKGNGTRHEKDD-- 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  936 eQTAQKAE----QSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKyeKETSEMITKH---DADIKGFKQNLL 1008
Cdd:COG4913    595 -RRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYswdEIDVASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1009 DAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHL 1088
Cdd:COG4913    672 ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 2024359622 1089 EMESKILLVQQDREELWtknEELNSENKKILKQKEAAEAK 1128
Cdd:COG4913    752 EERFAAALGDAVERELR---ENLEERIDALRARLNRAEEE 788
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 956-1191 2.30e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.98  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  956 ELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEmitkhdadikgfkqnLLDAEEALKAAQKKNDELETQAEELKKQA 1035
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE---------------YNELQAELEALQAEIDKLQAEIAEAEAEI 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1036 EQAKS-LSSVLASARK--------EIELMSDKMRDLISEKETLAQerntlklekesllsqhlemeskilLVQQDREELwt 1106
Cdd:COG3883     82 EERREeLGERARALYRsggsvsylDVLLGSESFSDFLDRLSALSK------------------------IADADADLL-- 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1107 knEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKELQANKD 1186
Cdd:COG3883    136 --EELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAA 213


                   ....*
gi 2024359622 1187 AVDVA 1191
Cdd:COG3883    214 AAAAA 218
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1533 2.58e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  841 EEQFALMSSELEQLKSnltvMETKLKEREEREQQLTEAKvklenDIAEIMKSSGDSSAQLMKMNDELRL--KERQLEQIQ 918
Cdd:COG4913    224 FEAADALVEHFDDLER----AHEALEDAREQIELLEPIR-----ELAERYAAARERLAELEYLRAALRLwfAQRRLELLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  919 LELTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQ---AKYEKETSEMITK 995
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERErrrARLEALLAALGLP 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  996 HDADIKGFKQN-------LLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKet 1068
Cdd:COG4913    375 LPASAEEFAALraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEA-- 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1069 laqerntLKLEKESL--LSQHLEMESK-----------------ILLVQQDREELWTknEELNSENKKILKQKEAAEAKS 1129
Cdd:COG4913    453 -------LGLDEAELpfVGELIEVRPEeerwrgaiervlggfalTLLVPPEHYAAAL--RWVNRLHLRGRLVYERVRTGL 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1130 RQESTEKvalISEKS---KLLSEIETAQADLLKITQENDALRSSESTllqqlKELQANKDAVDVACQ-KHIKEREELEHY 1205
Cdd:COG4913    524 PDPERPR---LDPDSlagKLDFKPHPFRAWLEAELGRRFDYVCVDSP-----EELRRHPRAITRAGQvKGNGTRHEKDDR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1206 QKLLEE------NDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQ------EKDLDLKSTHIALkneid 1273
Cdd:COG4913    596 RRIRSRyvlgfdNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeysWDEIDVASAEREI----- 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1274 cllqtnRSLQSEKEMLLKSREELcvslantanenQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMK 1353
Cdd:COG4913    671 ------AELEAELERLDASSDDL-----------AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1354 SSREASNSEKIHLLQEALfasEQRLLAE---------REELVNENKAVTEKLTKATADAVLAETAFTEK----INELNLE 1420
Cdd:COG4913    734 DRLEAAEDLARLELRALL---EERFAAAlgdaverelRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDAD 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1421 KESVFskslQFEKHNEALlrEKDELERKYSELLDEKKSLENAF-----SDMKREQEldfSAKRLLVQENTTLK------- 1488
Cdd:COG4913    811 LESLP----EYLALLDRL--EEDGLPEYEERFKELLNENSIEFvadllSKLRRAIR---EIKERIDPLNDSLKripfgpg 881

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 2024359622 1489 --YSIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENEL 1533
Cdd:COG4913    882 ryLRLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1547-2080 2.71e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 2.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1547 FNTCSSDIEILNRERTELQDKCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNnigfLEKEVEEMREKNKEFLT 1626
Cdd:TIGR04523   70 INNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNK----LEKQKKENKKNIDKFLT 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1627 EKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScvsvMLDELQHKYEVTEKEKM 1706
Cdd:TIGR04523  146 EIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLS----NLKKKIQKNKSLESQIS 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1707 ELVQENESLHAEWKSLviiNEEILKEKEKLSKEYYKL------HEKVVALLEQTDADfscrLLVSEGKHELLLEEMSNLA 1780
Cdd:TIGR04523  222 ELKKQNNQLKDNIEKK---QQEINEKTTEISNTQTQLnqlkdeQNKIKKQLSEKQKE----LEQNNKKIKELEKQLNQLK 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1781 LKLREIERLQAQTFMQKF--EADKRAEEVLQTMEKVTKEKDAIHQ--EKIETL-ASLENSRQTNEKLQNELDMlKQNNLK 1855
Cdd:TIGR04523  295 SEISDLNNQKEQDWNKELksELKNQEKKLEEIQNQISQNNKIISQlnEQISQLkKELTNSESENSEKQRELEE-KQNEIE 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1856 --NEEELTKSKELLNLENKKvEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQK----LEEERSVL 1929
Cdd:TIGR04523  374 klKKENQSYKQEIKNLESQI-NDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSeikdLTNQDSVK 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1930 NNQLLEMKKSLPSNTLRESTLKKEIDEERASLQKsisdTSALITQKDEELEKLRNEITVLRGEnasaktlqsvVKTLESD 2009
Cdd:TIGR04523  453 ELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ----KQKELKSKEKELKKLNEEKKELEEK----------VKDLTKK 518

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622 2010 KLKLEEKVKNLEQKLKAKSEQPLTVTSPSGDIAANLLQD---ESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQ 2080
Cdd:TIGR04523  519 ISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEnleKEIDEKNKEIEELKQTQKSLKKKQEEKQELID 592
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1416-1847 2.82e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 2.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1416 ELNLEKESVFSKSLQFEK-HNEALLREKDE----LERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYS 1490
Cdd:pfam01576  109 EEQLDEEEAARQKLQLEKvTTEAKIKKLEEdillLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM 188

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1491 IEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK 1570
Cdd:pfam01576  189 ISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE 268

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1571 LTGEVENMKENLTVEKKARILDK-------ESFLLERMELQNNIGFL----------EKEVEEMREKNKEFLTEKELLVQ 1633
Cdd:pfam01576  269 LEAQISELQEDLESERAARNKAEkqrrdlgEELEALKTELEDTLDTTaaqqelrskrEQEVTELKKALEEETRSHEAQLQ 348

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1634 EKEKSET--------KLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEK 1705
Cdd:pfam01576  349 EMRQKHTqaleelteQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQR 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1706 MELVQENESLHAEWKSLVIINEEILKEKEKLSKEY----YKLHEKVVALLEQTDA--DFSCRLLVSEGKHELLLEEMSNL 1779
Cdd:pfam01576  429 AELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVssleSQLQDTQELLQEETRQklNLSTRLRQLEDERNSLQEQLEEE 508

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2024359622 1780 ALKLREIERLQAQTFMQKFEADKRAEEVLQTME-------KVTKEKDAIHQEKIETLASLENSRQTNEKLQNELD 1847
Cdd:pfam01576  509 EEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEaleegkkRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELD 583
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 732-892 3.15e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.53  E-value: 3.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  732 LAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKD--SLEKEL 809
Cdd:COG1579     19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyeALQKEI 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  810 QLLKEKftsavdgAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmETKLKEREEREQQLTEAKVKLENDIAEI 889
Cdd:COG1579     99 ESLKRR-------ISDLEDEILELMERIEELEEELAELEAELAELEAEL---EEKKAELDEELAELEAELEELEAEREEL 168


                   ...
gi 2024359622  890 MKS 892
Cdd:COG1579    169 AAK 171
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1773-1991 3.53e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1773 LEEMSNLALKLRE-IERLQaqtfmqkfeadkRAEEVLQTMEKVTKEKDaiHQEKIETLASLENSRQTNEKLQNELDmlkq 1851
Cdd:COG4913    237 LERAHEALEDAREqIELLE------------PIRELAERYAAARERLA--ELEYLRAALRLWFAQRRLELLEAELE---- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1852 nnlKNEEELTKSKELLNLENKKVEELKKEFEALKLA-AAQKSQQLAALQEENVKLAEELGRSRDEvtsHQKLEEERSVLN 1930
Cdd:COG4913    299 ---ELRAELARLEAELERLEARLDALREELDELEAQiRGNGGDRLEQLEREIERLERELEERERR---RARLEALLAALG 372

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1931 NQLLEMKKSLPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRG 1991
Cdd:COG4913    373 LPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1798-2033 4.06e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.66  E-value: 4.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1798 FEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKEllnlENKKVEEL 1877
Cdd:PLN02939   124 QLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQ----EKIHVEIL 199

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1878 KKEFEALKLAAAQK-----------SQQLAALQEENVKLAEELGRSRDEVTSHQ-------KLEEERSVLNNQLLEMKKS 1939
Cdd:PLN02939   200 EEQLEKLRNELLIRgateglcvhslSKELDVLKEENMLLKDDIQFLKAELIEVAeteervfKLEKERSLLDASLRELESK 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1940 L---PSNTLRESTLKKEIDEERA-SLQ------KSISDTSALITQKDEELEKLRNEItvlrgeNASAKtlQSVVKTLESD 2009
Cdd:PLN02939   280 FivaQEDVSKLSPLQYDCWWEKVeNLQdlldraTNQVEKAALVLDQNQDLRDKVDKL------EASLK--EANVSKFSSY 351

                          250       260
                   ....*....|....*....|....*
gi 2024359622 2010 KLKL-EEKVKNLEQKLKAKSEQPLT 2033
Cdd:PLN02939   352 KVELlQQKLKLLEERLQASDHEIHS 376
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
757-1090 4.29e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 44.89  E-value: 4.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  757 EKQIQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINK 836
Cdd:COG4372      9 GKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQ 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  837 LNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:COG4372     89 LQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAA 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  917 IQLELTKANEKAV--QLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMIT 994
Cdd:COG4372    169 LEQELQALSEAEAeqALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDK 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  995 KHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERN 1074
Cdd:COG4372    249 EELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKL 328

                          330
                   ....*....|....*.
gi 2024359622 1075 TLKLEKESLLSQHLEM 1090
Cdd:COG4372    329 ELALAILLAELADLLQ 344
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
417-845 4.84e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  417 ELLNQLEEEKRKVEDLQFRVEEESITKGDLERKRQisedpeNVATVSEKSRIMELERDLALRVKEVAELRGRLESSkhID 496
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEA------ELEELREELEKLEKLLQLLPLYQELEALEAELAEL--PE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  497 DVDTSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVi 576
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL- 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 elwKSKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKLDYENE----------MSNLKLKQENEKSQHLK 646
Cdd:COG4717    226 ---EEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlglLALLFLLLAREKASLGK 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  647 EIEALKAkLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKELDVL--QAKCNEQTKLIGSLTQQIRA 724
Cdd:COG4717    303 EAEELQA-LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELeeELQLEELEQEIAALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  725 -SEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGgsskvSNLTKELQGKEQKLLDLEKNLSAVNQVKD 803
Cdd:COG4717    382 eDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE-----EELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|..
gi 2024359622  804 SLEKELQLLKEKftsavDGAENAQRAMQETINKLNQKEEQFA 845
Cdd:COG4717    457 ELEAELEQLEED-----GELAELLQELEELKAELRELAEEWA 493
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 663-1031 4.94e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.43  E-value: 4.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  663 EQTLENLKA-----KLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQK 737
Cdd:PRK10929    29 TQELEQAKAaktpaQAEIVE-----ALQSALNWLEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  738 ANsEGKLEIQKLSEQLQAAEKQIQNlETEKVGGSSKVSNLTKELQGKEQKLL-DLEKNL-------SAVNQVKD-SLEKE 808
Cdd:PRK10929   104 TD-ALEQEILQVSSQLLEKSRQAQQ-EQDRAREISDSLSQLPQQQTEARRQLnEIERRLqtlgtpnTPLAQAQLtALQAE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  809 LQLLKEKftsaVDGAENAQRAM---QETIN---KLNQKeeQFALMSSELEQLKSNLTVMETKLKERE-EREQQLTEAKVK 881
Cdd:PRK10929   182 SAALKAL----VDELELAQLSAnnrQELARlrsELAKK--RSQQLDAYLQALRNQLNSQRQREAERAlESTELLAEQSGD 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  882 LENDIAEIMKSSGDSSAQLmkmndelrlkERQLEQIQLELTKANEKAVQLQKnVEQTAQK-AEQSQ--------QETLKT 952
Cdd:PRK10929   256 LPKSIVAQFKINRELSQAL----------NQQAQRMDLIASQQRQAASQTLQ-VRQALNTlREQSQwlgvsnalGEALRA 324

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  953 HQEELKKM---QDQLTDMkKQMETSQNQYKDLQAKYEKETsemitkhdadikgfkQNLLDAEEALKAAQKK--NDELETQ 1027
Cdd:PRK10929   325 QVARLPEMpkpQQLDTEM-AQLRVQRLRYEDLLNKQPQLR---------------QIRQADGQPLTAEQNRilDAQLRTQ 388


                   ....
gi 2024359622 1028 AEEL 1031
Cdd:PRK10929   389 RELL 392
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2110-2127 5.62e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 38.99  E-value: 5.62e-04
                           10
                   ....*....|....*...
gi 2024359622 2110 RLFCDICGCFDlHDTEDC 2127
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
46 PHA02562
endonuclease subunit; Provisional
 946-1212 5.78e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.01  E-value: 5.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  946 QQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEketsEMITKHDADIKGFKQNLLDAEEALKAAQKkndELE 1025
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQ----NKYDELVEEAKTIKAEIEELTDELLNLVM---DIE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1026 TQAEELKKQAEQAKSLSSVLASARKEIELMSDK------MRDLISEKETLAQERNTLKlekesllsqhlEMESKILLVQQ 1099
Cdd:PHA02562   252 DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLK-----------ELQHSLEKLDT 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1100 DREELWTKNEELNSENKKILKQKeaaeAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQEndalrssestllqqLK 1179
Cdd:PHA02562   321 AIDELEEIMDEFNEQSKKLLELK----NKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE--------------LA 382

                          250       260       270
                   ....*....|....*....|....*....|...
gi 2024359622 1180 ELQANKDAVDVACQKHIKEREELEHYQKLLEEN 1212
Cdd:PHA02562   383 KLQDELDKIVKTKSELVKEKYHRGIVTDLLKDS 415
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 420-808 6.38e-04

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.85  E-value: 6.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  420 NQLEEEKRKVEDLQFRVEEESITKGDLERKRQISEDPENVATvsekSRIMELERDLALRVKEVAElrgrlesskhiddvd 499
Cdd:PLN03229   420 NMKKREAVKTPVRELEGEVEKLKEQILKAKESSSKPSELALN----EMIEKLKKEIDLEYTEAVI--------------- 480

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  500 tSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASnermgkenESLKTKLDHANkensdviELW 579
Cdd:PLN03229   481 -AMGLQERLENLREEFSKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNY--------LSLKYKLDMLN-------EFS 544

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  580 KSKlesAIASHQQAMEELKVSFNKGVgAQTAEFAELKTQMEKVKLDYENEmsnlKLKQENEKSQHLKEiEALKAKLlEVT 659
Cdd:PLN03229   545 RAK---ALSEKKSKAEKLKAEINKKF-KEVMDRPEIKEKMEALKAEVASS----GASSGDELDDDLKE-KVEKMKK-EIE 614

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLENLKAKLESVEDQHLVEMEDTLNklqeaeikvkelDVLQAKcneqtklIGSLTQQIRASEEKLLDLAALQKAN 739
Cdd:PLN03229   615 LELAGVLKSMGLEVIGVTKKNKDTAEQTPP------------PNLQEK-------IESLNEEINKKIERVIRSSDLKSKI 675

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  740 SEGKLEIQKLSEQLQAAEKQ-IQNLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKE 808
Cdd:PLN03229   676 ELLKLEVAKASKTPDVTEKEkIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARETAAESNGSLKND 745
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 652-1065 6.46e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 44.83  E-value: 6.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  652 KAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEdtlNKLQEAEIKVKELDVLQAK--CNEQTKLIGSLTQQIRASEEKL 729
Cdd:PRK04778    52 KVKKLNLTGQSEEKFEEWRQKWDEIVTNSLPDIE---EQLFEAEELNDKFRFRKAKheINEIESLLDLIEEDIEQILEEL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  730 LDLAALQKANSEGKLEIQKLSEQLQAA---------------EKQIQNLETEKvggsSKVSNLTKE---LQGKEQkLLDL 791
Cdd:PRK04778   129 QELLESEEKNREEVEQLKDLYRELRKSllanrfsfgpaldelEKQLENLEEEF----SQFVELTESgdyVEAREI-LDQL 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  792 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQE--------TINK-LNQKEEQFALMSSELEQLKsnLTVME 862
Cdd:PRK04778   204 EEELAALEQIMEEIPELLKELQTELPDQLQELKAGYRELVEegyhldhlDIEKeIQDLKEQIDENLALLEELD--LDEAE 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  863 TKLKEREEREQQL---TEAKVKLENDIAEIMKSSGDSSAQLMKMNDELrlkerqleqiQLELTkanekavQLQKNVEQTA 939
Cdd:PRK04778   282 EKNEEIQERIDQLydiLEREVKARKYVEKNSDTLPDFLEHAKEQNKEL----------KEEID-------RVKQSYTLNE 344

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  940 qkaeqSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEkETSEMITKHDADIKGFKQNLLDAEEALKAAQK 1019
Cdd:PRK04778   345 -----SELESVRQLEKQLESLEKQYDEITERIAEQEIAYSELQEELE-EILKQLEEIEKEQEKLSEMLQGLRKDELEARE 418

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359622 1020 KNDELETQAEELKKQAEQAKsLSSVLASARKEIELMSDKMRDLISE 1065
Cdd:PRK04778   419 KLERYRNKLHEIKRYLEKSN-LPGLPEDYLEMFFEVSDEIEALAEE 463
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
346-820 7.40e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 7.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  346 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHvlEMEAKMDQLRAMVEAADREKVELLNQLEEE 425
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  426 KRKVEDLQFRVEEESITKGDLERKRQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLESSKH-IDDVDTSLSL 504
Cdd:COG4717    159 RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEeLEQLENELEA 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  505 LQEISSLQEKM-----AAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANkensdvielw 579
Cdd:COG4717    239 AALEERLKEARlllliAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ---------- 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  580 ksKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKTQMEKVKldyenemsnlklkqeneksQHLKEIEALKAKLLEVT 659
Cdd:COG4717    309 --ALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ-------------------ELLREAEELEEELQLEE 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  660 EEKEQTLENLKAKLESVEdqhlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRAS--EEKLLDLAALQK 737
Cdd:COG4717    368 LEQEIAALLAEAGVEDEE-----ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEelEEELEELEEELE 442

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  738 ANSEgklEIQKLSEQLQAAEKQIQNLETEKvggssKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFT 817
Cdd:COG4717    443 ELEE---ELEELREELAELEAELEQLEEDG-----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514


                   ...
gi 2024359622  818 SAV 820
Cdd:COG4717    515 PPV 517
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1556-1819 8.60e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 8.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1556 ILNRERTELQDKCQKLtG--EVENMKENLTVEkkaRILDKESfllERMELQNNIGFLEKEVEemreknKEFLTEKELLVQ 1633
Cdd:PRK05771    13 TLKSYKDEVLEALHEL-GvvHIEDLKEELSNE---RLRKLRS---LLTKLSEALDKLRSYLP------KLNPLREEKKKV 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1634 EKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHScVSVMLDELQHK-------YEVTEKEKM 1706
Cdd:PRK05771    80 SVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGFkyvsvfvGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1707 ELVQENESLHAEWKS-------LVIINEeilkekeklsKEYYKLHEKVVAlleqtDADFScRLLVSEGKH--ELLLEEMS 1777
Cdd:PRK05771   159 ELKLESDVENVEYIStdkgyvyVVVVVL----------KELSDEVEEELK-----KLGFE-RLELEEEGTpsELIREIKE 222

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359622 1778 NLALKLREIERLQAQTfmqKFEADKRAEEVLQTMEKVTKEKD 1819
Cdd:PRK05771   223 ELEEIEKERESLLEEL---KELAKKYLEELLALYEYLEIELE 261
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
695-1150 9.30e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 9.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  695 EIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAE--KQIQNLETEKVGGSS 772
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  773 KVSNLTKELQGKEQKLLDLEKNLSAVNQVKDSLEKELQLL----KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMS 848
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLslatEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  849 SELEQLKSNLTVMETKLKEREEREQQLTEAKV-------KLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLEL 921
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALlallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  922 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKdlQAKYEKETSEMITKHDADik 1001
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVE-- 382

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1002 gfkqNLLDAEEALKAAQKKNdELETQAEELKKQAEQAKSLSSVLASARKEIELMsDKMRDLISEKETLAQERNTLKLEKE 1081
Cdd:COG4717    383 ----DEEELRAALEQAEEYQ-ELKEELEELEEQLEELLGELEELLEALDEEELE-EELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359622 1082 SLLSQHLEMESKILLVQQdREELWTKNEELNSENKKILKQKEAA----EAKSRQESTEKVALISEKSKLLSEI 1150
Cdd:COG4717    457 ELEAELEQLEEDGELAEL-LQELEELKAELRELAEEWAALKLALelleEAREEYREERLPPVLERASEYFSRL 528
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
791-1110 9.36e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.74  E-value: 9.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  791 LEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREE 870
Cdd:COG4372     29 LSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  871 REQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQETL 950
Cdd:COG4372    109 EAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDEL 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  951 KTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEE 1030
Cdd:COG4372    189 LKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAIL 268

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1031 LKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEE 1110
Cdd:COG4372    269 VEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLV 348
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
505-947 9.79e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 9.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  505 LQEISSLQEKMAAAGKEHQ--REMSSLKEKFESSEEALRKEIKTLSASNERMGK--ENESLKTKLDHANKENSDVIELWK 580
Cdd:COG4717     70 LKELKELEEELKEAEEKEEeyAELQEELEELEEELEELEAELEELREELEKLEKllQLLPLYQELEALEAELAELPERLE 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  581 sKLESAIASHQQAMEELKvsfnkgvgAQTAEFAELKTQMEkvklDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTE 660
Cdd:COG4717    150 -ELEERLEELRELEEELE--------ELEAELAELQEELE----ELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  661 EKEQTLENLKAKLESVEDQHlvEMEDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQ--QIRASEEKLLDLAALQKA 738
Cdd:COG4717    217 EAQEELEELEEELEQLENEL--EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTiaGVLFLVLGLLALLFLLLA 294

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  739 NSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEqkLLDLEKNLSAVNQVKDSLEKELQL------L 812
Cdd:COG4717    295 REKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLE--LLDRIEELQELLREAEELEEELQLeeleqeI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  813 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVM--ETKLKEREEREQQLTEAKVKLENDIAEIM 890
Cdd:COG4717    373 AALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELleALDEEELEEELEELEEELEELEEELEELR 452

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622  891 KSSGDSSAQLMKMN-----DELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAEQSQQ 947
Cdd:COG4717    453 EELAELEAELEQLEedgelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1023-1624 1.01e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1023 ELETQAEELKKQAEQAKSLSSVLASARKEIELMSDkMRDLISEKETLAQERNTLKLEKESLlsQHLEMESKILLVQQDRE 1102
Cdd:COG4913    222 DTFEAADALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELE 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1103 ELwtkneelnsenkkilkQKEAAEAKSRQESTEKvalisekskllsEIETAQADLLKITQendALRSSESTLLQQLKELQ 1182
Cdd:COG4913    299 EL----------------RAELARLEAELERLEA------------RLDALREELDELEA---QIRGNGGDRLEQLEREI 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1183 ANKdavdvacQKHIKERE-ELEHYQKLLEendrvikdkdDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1261
Cdd:COG4913    348 ERL-------ERELEERErRRARLEALLA----------ALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEA 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1262 KSTHIALKNEIDCLLQTNRSLQSEK----EMLLKSREELCvslantanenQALKLRKDE-------MQTELETER----- 1325
Cdd:COG4913    411 EAALRDLRRELRELEAEIASLERRKsnipARLLALRDALA----------EALGLDEAElpfvgelIEVRPEEERwrgai 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1326 ---------------EKLEKMTK--DNMDLKASLSS--LSNFLEEMKSSREASNS--EKIHLLQEALFASEQRLLAER-- 1382
Cdd:COG4913    481 ervlggfaltllvppEHYAAALRwvNRLHLRGRLVYerVRTGLPDPERPRLDPDSlaGKLDFKPHPFRAWLEAELGRRfd 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1383 -------EELVNENKAVT-EKLTKATADA-------------VLAETAfTEKINELNLEKesvfskslqfekhnEALLRE 1441
Cdd:COG4913    561 yvcvdspEELRRHPRAITrAGQVKGNGTRhekddrrrirsryVLGFDN-RAKLAALEAEL--------------AELEEE 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1442 KDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTtlkysIEALEEELKKKNLENQELIAcrsdLSDLLKE 1521
Cdd:COG4913    626 LAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE-----IAELEAELERLDASSDDLAA----LEEQLEE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1522 AQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQK-LTGEVENMKENLTVEKKARILdKESFLLER 1600
Cdd:COG4913    697 LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGDAVEREL-RENLEERI 775

                          650       660
                   ....*....|....*....|....*
gi 2024359622 1601 MELQNNIGFLEKEVEE-MREKNKEF 1624
Cdd:COG4913    776 DALRARLNRAEEELERaMRAFNREW 800
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 647-795 1.07e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 44.30  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  647 EIEALKAKLLEVTEEKEQtlenLKAKLESVEDQHLVEMEDTLNKLQEaeikvkELDVLQAKCNEQTKLIGSLTQQIRASE 726
Cdd:COG0542    412 ELDELERRLEQLEIEKEA----LKKEQDEASFERLAELRDELAELEE------ELEALKARWEAEKELIEEIQELKEELE 481

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359622  727 EKLLDLAALQKAnsegkleiqklSEQLQAAEKQIQNLETEKVGGS---SKVSNLT-----KELQGKEQKLLDLEKNL 795
Cdd:COG0542    482 QRYGKIPELEKE-----------LAELEEELAELAPLLREEVTEEdiaEVVSRWTgipvgKLLEGEREKLLNLEEEL 547
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 818-1048 1.10e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.67  E-value: 1.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  818 SAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDsS 897
Cdd:COG3883     13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGE-R 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  898 AQLMKMNDELRLKERQLEQIQlELTKANEKAVQLQKNVEQTAQKAEQ--SQQETLKTHQEELKKMQDQLTDMKKQMETSQ 975
Cdd:COG3883     92 ARALYRSGGSVSYLDVLLGSE-SFSDFLDRLSALSKIADADADLLEElkADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2024359622  976 NQYKDLQAKYEKETsemitkhdADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASA 1048
Cdd:COG3883    171 AELEAQQAEQEALL--------AQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1848-2080 1.15e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1848 MLKQNNLKNEEELTKSKELLNlenKKVEELKKEFEAL--KLAAAQKSQQLAALQEENVKLAEELGRSRDEVTshqKLEEE 1925
Cdd:COG3206    161 YLEQNLELRREEARKALEFLE---EQLPELRKELEEAeaALEEFRQKNGLVDLSEEAKLLLQQLSELESQLA---EARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1926 RSVLNNQLLEMKKSLPSN-----TLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGEnaSAKTLQ 2000
Cdd:COG3206    235 LAEAEARLAALRAQLGSGpdalpELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ--LQQEAQ 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 2001 SVVKTLESDKLKLEEKVKNLEQKLKAKSEQpltvtspsgdiAANLLQDES-AEDKQQEIDFLNSVIVDLQRRNEELNLKI 2079
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEAR-----------LAELPELEAeLRRLEREVEVARELYESLLQRLEEARLAE 381


                   .
gi 2024359622 2080 Q 2080
Cdd:COG3206    382 A 382
ClyA_NheA-like cd22654
Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This ...
 717-996 1.16e-03

Bacillus cereus non-hemolytic enterotoxin (Nhe) component A (NheA), and similar proteins; This model contains Bacillus cereus tripartite non-hemolytic enterotoxin (Nhe) component A (NheA), a member of the cytolysin A (ClyA) family of alpha pore-forming toxins (alpha-PFTs). Non-hemolytic enterotoxin (Nhe), despite its name, is hemolytic and able to lyse erythrocytes from various mammalian organisms. It consists of three proteins, NheA, NheB and NheC, encoded by one operon containing three genes nheA, nheB and nheC, respectively. Separately, these three proteins show no toxicity; maximal activity is seen only when all three components are presented. The NheB and NheC components are able to bind to cell membranes while NheA is not; NheC primes the host cell for the formation of ion permeable NheB/C pores. Binding of NheA to NheB/NheC is thought to be the final stage of pore formation. Structure of NheA shows an elongated, almost entirely alpha-helical protein with an enlarged "head" domain compared with other cytolysins, displaying on its surface an enlarged beta-tongue which is of amphipathic rather than hydrophobic nature. It has been proposed that NheA could even form beta-barrel pores.


Pssm-ID: 439152 [Multi-domain]  Cd Length: 333  Bit Score: 43.41  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  717 SLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNletekvggsskvsnltkelqgkeqkllDLEKNLS 796
Cdd:cd22654     66 NFSQRFNNYYDKLYDLAGKINEDEQAKEDFLNGINKLQSQLQTIQN---------------------------SMEQTSS 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  797 AVNQVKDSLEKELQLLKEKFTSAVD--GAENAQRA-MQETINKLNQ--KEEQFALMSSELEQLKSNLTVMETKLKEREER 871
Cdd:cd22654    119 NLNRFKTLLDADSKNFSTDAKKAIDslSGSNGEIAqLRTQIKTINDeiQEELTKILNRPIEVGDGSINIGKQVFTITITT 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  872 EQQLTEAKVKLENDIAEIMKSSGDssaQLMKMNDELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQKAE--QSQQET 949
Cdd:cd22654    199 ATTKTVDVTSIGGLINGIGNASDD---EVKEAANKIQQKQKELVDLIKKLSDAEIQATQLTLVEDQVNGFTEliKRQIAT 275

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 2024359622  950 LKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYE--KETSEMITKH 996
Cdd:cd22654    276 LENLVEDWEMLNQNMNQLQTNVNSGKIDSKLLQKQLKqiKKISDELNKQ 324
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1022-1409 1.21e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.52  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1022 DELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDR 1101
Cdd:pfam19220   20 EDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1102 EELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLLQQLKEL 1181
Cdd:pfam19220  100 REAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRL 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1182 QANKDAVDVACQKHIKEREELEhyqKLLEENDRVIkdkDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLDL 1261
Cdd:pfam19220  180 QALSEEQAAELAELTRRLAELE---TQLDATRARL---RALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEAL 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1262 KSTHIALkneiDCLLQTNRSLQSEKEMLLKSREElcvSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKAS 1341
Cdd:pfam19220  254 TARAAAT----EQLLAEARNQLRDRDEAIRAAER---RLKEASIERDTLERRLAGLEADLERRTQQFQEMQRARAELEER 326

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622 1342 LSSLSNFLEEmKSSREASNSEKIHLLQEALFASEQRLLAEREELVNENKAVTEKLTKATADAVLAETA 1409
Cdd:pfam19220  327 AEMLTKALAA-KDAALERAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQRERAERALAQGA 393
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
648-921 1.22e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  648 IEALKAKLLEVTEEkeqtLENLKAKLESVEDQHlvemeDTLNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEE 727
Cdd:COG4913    612 LAALEAELAELEEE----LAEAEERLEALEAEL-----DALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  728 KLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEkvggsskVSNLTKELQGKEQKLLDLEKnlSAVNQVKDSLEK 807
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-------LEQAEEELDELQDRLEAAED--LARLELRALLEE 753

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  808 EL-QLLKEKFTSAVdgAENAQRAMQETINKLNQKEEQFA-LMSSELEQLKSNLTVMETKLKEREEREQQLTEAK----VK 881
Cdd:COG4913    754 RFaAALGDAVEREL--RENLEERIDALRARLNRAEEELErAMRAFNREWPAETADLDADLESLPEYLALLDRLEedglPE 831

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 2024359622  882 LENDIAE-IMKSSGDSSAQL-MKMNDELRLKERQLEQIQLEL 921
Cdd:COG4913    832 YEERFKElLNENSIEFVADLlSKLRRAIREIKERIDPLNDSL 873
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 343-571 1.22e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  343 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRdghdRHVLEMEAKMDQLRAMVEAADREKVELLNQL 422
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----RRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  423 EEEKRKVEDL---QFRVEEESITKGDLErkrqiSEDPENVAtvsekSRIMELERDLALRVKEVAELRGRLEsskhidDVD 499
Cdd:COG4942    100 EAQKEELAELlraLYRLGRQPPLALLLS-----PEDFLDAV-----RRLQYLKYLAPARREQAEELRADLA------ELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622  500 TSLSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKE 571
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK12704 PRK12704
phosphodiesterase; Provisional
 613-749 1.22e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  613 AELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEvteeKEQTLENLKAKLESVEDQHLVEMEDTLNKLQ 692
Cdd:PRK12704    49 KEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQ----KEENLDRKLELLEKREEELEKKEKELEQKQQ 124

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359622  693 EAEIKVKELDVLQAKCNEQTKLIGSLTQqirasEE--KLLdlaaLQKANSEGKLEIQKL 749
Cdd:PRK12704   125 ELEKKEEELEELIEEQLQELERISGLTA-----EEakEIL----LEKVEEEARHEAAVL 174
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
786-1260 1.32e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  786 QKLLDLEKNLSAVNQVKDSLEkELQLLKEKFTSAVDGAEnAQRAMQETINKLnQKEEQFALMSSELEQLKSNLTVMETKL 865
Cdd:COG4913    235 DDLERAHEALEDAREQIELLE-PIRELAERYAAARERLA-ELEYLRAALRLW-FAQRRLELLEAELEELRAELARLEAEL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  866 KEREEREQQLTEAKVKLENDIAEimkSSGDSSAQLMKmndELRLKERQLEQIQLELTKANEKAVQLQKNVEQTAQ--KAE 943
Cdd:COG4913    312 ERLEARLDALREELDELEAQIRG---NGGDRLEQLER---EIERLERELEERERRRARLEALLAALGLPLPASAEefAAL 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  944 QSQ-QETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQAkyeketsemitkhdaDIKGFKQN-------LLDAEEALK 1015
Cdd:COG4913    386 RAEaAALLEALEEELEALEEALAEAEAALRDLRRELRELEA---------------EIASLERRksniparLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1016 AA-QKKNDELETQAEELKKQAEQAK--------------SL---SSVLASARKEIE-------LMSDKMRDLISEKETLA 1070
Cdd:COG4913    451 EAlGLDEAELPFVGELIEVRPEEERwrgaiervlggfalTLlvpPEHYAAALRWVNrlhlrgrLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1071 QERNTL--KLE-KESLLSQHLEME--SKILLVQQDREE--------------------LWTKNEE----------LNSEN 1115
Cdd:COG4913    531 LDPDSLagKLDfKPHPFRAWLEAElgRRFDYVCVDSPEelrrhpraitragqvkgngtRHEKDDRrrirsryvlgFDNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1116 KKILKQKEAAEAKSR-QESTEKVALISEKSKLLSEIETAQADLLKITQENDALRSSESTLL---QQLKELQANKDAVDVA 1191
Cdd:COG4913    611 KLAALEAELAELEEElAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAeleAELERLDASSDDLAAL 690

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359622 1192 cqkhikeREELEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSAQEKDLD 1260
Cdd:COG4913    691 -------EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE 752
PRK12704 PRK12704
phosphodiesterase; Provisional
 1782-1904 1.48e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.61  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1782 KLREIERlQAQTFMQkfEADKRAEEVLQtmEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELdMLKQNNLKN----- 1856
Cdd:PRK12704    32 KIKEAEE-EAKRILE--EAKKEAEAIKK--EALLEAKEEIHKLRNEFEKELRERRNELQKLEKRL-LQKEENLDRklell 105

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 2024359622 1857 ---EEELTKSKELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVK 1904
Cdd:PRK12704   106 ekrEEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK 156
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1120-1359 1.80e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1120 KQKEAAEAKSRQESTEKVALISEKSKLLSEIETAQAdllKITQENDALRSSESTLLQQLKELQANkdavdvacqkhikeR 1199
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALER---RIAALARRIRALEQELAALEAELAEL--------------E 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1200 EELEHYQKLLEENDRVIKDKDDVIQRL-QSSYDDLARNQRELLQEVSILTAerdsaqekdldLKSTHIALKNEIDCLLQT 1278
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLgRQPPLALLLSPEDFLDAVRRLQY-----------LKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1279 NRSLQSEKEMLLKSREELCVSLANTANENQALKLRKDEMQTELETEREKLEKMTKDNMDLKASLSSLSNFLEEMKSSREA 1358
Cdd:COG4942    159 LAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   .
gi 2024359622 1359 S 1359
Cdd:COG4942    239 A 239
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-550 1.84e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  335 ARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALVRDGHDRhVLEMEAKMDQLRAMVEAADRE 414
Cdd:COG4913    630 EERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEAELEELEEE 707

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  415 KVELLNQLEEEKRKVEDLQFRVEE------------ESITKGDLERKRQISEDPENVATVSEksrimELERDLALRVKEV 482
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDElqdrleaaedlaRLELRALLEERFAAALGDAVERELRE-----NLEERIDALRARL 782

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  483 AELRGRLESSKH---------IDDVDTSLS-------LLQEISS-----LQEKMAAAGKEH-QREMSSLKEKFESSEEAL 540
Cdd:COG4913    783 NRAEEELERAMRafnrewpaeTADLDADLEslpeylaLLDRLEEdglpeYEERFKELLNENsIEFVADLLSKLRRAIREI 862

                          250
                   ....*....|
gi 2024359622  541 RKEIKTLSAS 550
Cdd:COG4913    863 KERIDPLNDS 872
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1358-1580 2.46e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1358 ASNSEKIHLLQEALFASEQRLlAEREELVNENKAVTEKLTKATADAVLAETAFTEKINELNLEKESVFSKSLQFEKHNEA 1437
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEI-AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1438 LLREKDELERKYSELLDE--KKSLENAFSDMKREQELDFSAKRL--LVQENTTLKYSIEALEEELKKKNLENQELIACRS 1513
Cdd:COG4942     95 LRAELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2024359622 1514 DLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRERTELQDKCQKLTGEVENMKE 1580
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PTZ00121 PTZ00121
MAEBL; Provisional
 1784-2026 2.70e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1784 REIERLQAQTFMQKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKS 1863
Cdd:PTZ00121  1278 RKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD 1357

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1864 KELLNLENKKVEELKKEFEALKLAAAQKSQQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSN 1943
Cdd:PTZ00121  1358 EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAK 1437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1944 TLRESTLKKEIDEERASLQKSISDtsalITQKDEELEKLRNeitvLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQK 2023
Cdd:PTZ00121  1438 KKAEEAKKADEAKKKAEEAKKAEE----AKKKAEEAKKADE----AKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAK 1509


                   ...
gi 2024359622 2024 LKA 2026
Cdd:PTZ00121  1510 KKA 1512
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1602-2000 2.76e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1602 ELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAele 1681
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ--- 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1682 dvhscvsvmLDELQHKYEVTEKEKMELVQENESLHAEWKSLviinEEILKEKEKLSKEYYKLHEKVVALLEQTDADFSCR 1761
Cdd:COG4717    127 ---------LLPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLSLATEEE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1762 LLVSEGKHELLLEEMSNL--ALKLREIERLQAQTFMQKFEADKRAEEVLQTMEK-------------------------- 1813
Cdd:COG4717    194 LQDLAEELEELQQRLAELeeELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallallglggsllslil 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1814 -------------------VTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKV 1874
Cdd:COG4717    274 tiagvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1875 EELKKEFEALKLAAAQKSQQlAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLpsNTLRESTLKKEI 1954
Cdd:COG4717    354 REAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGEL--EELLEALDEEEL 430

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 2024359622 1955 DEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQ 2000
Cdd:COG4717    431 EEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQ 476
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 683-966 3.21e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 3.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  683 EMEDTLNKLQEAEIkVKELDVLQAKCNEQTKLIGSLTQQIraseEKLLDLaaLQKANSEGKLEIQKLSE-QLQAAEKQIQ 761
Cdd:PRK05771    17 YKDEVLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKL----SEALDK--LRSYLPKLNPLREEKKKvSVKSLEELIK 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  762 NLETEKVGGSSKVSNLTKELQGKEQKLLDLEKNLSAVNQVKDsLEKELQLLKE-KFTSAVDGaenaqramqeTINKlNQK 840
Cdd:PRK05771    90 DVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGN-FDLDLSLLLGfKYVSVFVG----------TVPE-DKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  841 EEQFALMSS----ELEQLKSNLTVMETKLKEREEreQQLTEAKvKLENDIAEImKSSGDSSAQLMKMNDELRLKERQLEQ 916
Cdd:PRK05771   158 EELKLESDVenveYISTDKGYVYVVVVVLKELSD--EVEEELK-KLGFERLEL-EEEGTPSELIREIKEELEEIEKERES 233

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622  917 IQLELTKANEKAVQLQKNV----EQTAQKAEQSQQ--ETLKT----------HQEELKKMQDQLTD 966
Cdd:PRK05771   234 LLEELKELAKKYLEELLALyeylEIELERAEALSKflKTDKTfaiegwvpedRVKKLKELIDKATG 299
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 743-912 3.40e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 3.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  743 KLEIQKLSEQLQAAEKQIQNLETEkvggsskvsnltKELQGKEQKLLDLEKnlsavnqvKDSLEKELQLLKEKFtsavDG 822
Cdd:COG0542    403 RMEIDSKPEELDELERRLEQLEIE------------KEALKKEQDEASFER--------LAELRDELAELEEEL----EA 458

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  823 AENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEreerEQQLTEAKVKlENDIAEIM-KSSG------- 894
Cdd:COG0542    459 LKARWEAEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAE----LAPLLREEVT-EEDIAEVVsRWTGipvgkll 533

                          170
                   ....*....|....*....
gi 2024359622  895 -DSSAQLMKMNDElrLKER 912
Cdd:COG0542    534 eGEREKLLNLEEE--LHER 550
PRK11281 PRK11281
mechanosensitive channel MscK;
832-1202 3.43e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  832 ETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKMND------ 905
Cdd:PRK11281    46 DALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLStlslrq 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  906 -ELRLKER--QLEQIQLELTKANEKAVQLQKNVEQtAQKA-EQSQQETlkthqEELKKMQDQLTDMKKQMETSQnqykdl 981
Cdd:PRK11281   126 lESRLAQTldQLQNAQNDLAEYNSQLVSLQTQPER-AQAAlYANSQRL-----QQIRNLLKGGKVGGKALRPSQ------ 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  982 QAKYEKETSEMITKHDadikgFKQNLLDAEEALKA-AQKKNDELetqAEELKKQAEQAKSLSSVLASarKEIELMSDKMR 1060
Cdd:PRK11281   194 RVLLQAEQALLNAQND-----LQRKSLEGNTQLQDlLQKQRDYL---TARIQRLEHQLQLLQEAINS--KRLTLSEKTVQ 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1061 DLISEKETLAQERNTLkLEKESLLSQHLemeSKILLVQQDR------EELWTKN--EELNSENKKILKQKEAAEAK---S 1129
Cdd:PRK11281   264 EAQSQDEAARIQANPL-VAQELEINLQL---SQRLLKATEKlntltqQNLRVKNwlDRLTQSERNIKEQISVLKGSlllS 339

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2024359622 1130 RQESTEKVALISekSKLLSEIETAQADL----LKITQENDALrSSESTLLQQLKELQANK--DAVDVACQKHIKEREEL 1202
Cdd:PRK11281   340 RILYQQQQALPS--ADLIEGLADRIADLrleqFEINQQRDAL-FQPDAYIDKLEAGHKSEvtDEVRDALLQLLDERREL 415
PRK11281 PRK11281
mechanosensitive channel MscK;
1804-1975 3.46e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1804 AEEVLQTMEKVTKEKDAIHQEK---------IETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKskellnLENKKV 1874
Cdd:PRK11281    38 EADVQAQLDALNKQKLLEAEDKlvqqdleqtLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEA------LKDDND 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1875 EELKKEFEALKLAA-----AQKSQQLAALQE------------------------ENVKLAEEL---------GRSRDEV 1916
Cdd:PRK11281   112 EETRETLSTLSLRQlesrlAQTLDQLQNAQNdlaeynsqlvslqtqperaqaalyANSQRLQQIrnllkggkvGGKALRP 191

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622 1917 TSHQKLEEERSVLNNQLLEMKKSLPSNTLRESTLKKEID---EERASLQKSISDTSALITQK 1975
Cdd:PRK11281   192 SQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltARIQRLEHQLQLLQEAINSK 253
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1823-1941 3.55e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 42.51  E-value: 3.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1823 QEKIETL-ASLENSRQTNEKLQNELDMLKQNNLKNEEELtkskellnleNKKVEELKKEFEALKLAAAQKSQQ-LAALQE 1900
Cdd:PRK00409   515 KEKLNELiASLEELERELEQKAEEAEALLKEAEKLKEEL----------EEKKEKLQEEEDKLLEEAEKEAQQaIKEAKK 584

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 2024359622 1901 ENVKLAEELGRSRDEVTSHQK---LEEERSVLNNQLLEMKKSLP 1941
Cdd:PRK00409   585 EADEIIKELRQLQKGGYASVKaheLIEARKRLNKANEKKEKKKK 628
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 654-1086 3.72e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.63  E-value: 3.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  654 KLLEVTEEKEQTLENLKAKLESVEDQHlVEMEDTLNKLQEAEikvKELDV-LQAkCNEQTKLIGSLTQQIRASEEKLLDL 732
Cdd:COG3096    282 ELSERALELRRELFGARRQLAEEQYRL-VEMARELEELSARE---SDLEQdYQA-ASDHLNLVQTALRQQEKIERYQEDL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  733 AALqkansEGKLEIQklSEQLQAAEKQIQNLETEKVGGSSKVSNLTKELQGKEQKLldleknlsavnqvkdsleKELQLL 812
Cdd:COG3096    357 EEL-----TERLEEQ--EEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQAL------------------DVQQTR 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  813 KEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKS 892
Cdd:COG3096    412 AIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERS 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  893 SGDSSA-QLMKMNDELRLKERQLEQIQLELTKAnEKAVQLQKNVEQTAQKAEQSQ------QETLKTHQEELKKMQDQLT 965
Cdd:COG3096    492 QAWQTArELLRRYRSQQALAQRLQQLRAQLAEL-EQRLRQQQNAERLLEEFCQRIgqqldaAEELEELLAELEAQLEELE 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  966 DmkkQMETSQNQYKDLQAKyeketsemitkhdadikgfkqnlldaEEALKAAQKkndELETQAEELKKQAEQAKSLSSVL 1045
Cdd:COG3096    571 E---QAAEAVEQRSELRQQ--------------------------LEQLRARIK---ELAARAPAWLAAQDALERLREQS 618

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 2024359622 1046 ASARKEIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQ 1086
Cdd:COG3096    619 GEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQ 659
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 538-859 3.73e-03

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 42.25  E-value: 3.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  538 EALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKSKLESAIASHQQAMEELKVSFNKGVGAQTAE----FA 613
Cdd:COG5185    242 ESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEeqlaAA 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  614 ELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEVTEEKEqtLENLKAKLESVEDQHLVEMEDTLNKLQE 693
Cdd:COG5185    322 EAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVE--LSKSSEELDSFKDTIESTKESLDEIPQN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  694 AEIKVKELDVLQAKcneqtkligSLTQQIRASEEKLLDLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSK 773
Cdd:COG5185    400 QRGYAQEILATLED---------TLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYD 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  774 VSNltkelQGKEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQ 853
Cdd:COG5185    471 EIN-----RSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLI 545


                   ....*.
gi 2024359622  854 LKSNLT 859
Cdd:COG5185    546 PASELI 551
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1413-1880 3.76e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1413 KINELNLEKESVFSKSLQFEKHNEALLREKDELERKYSELLDEKKSLENAFSDMKREQELDFSAKRLLVQENTTLKYSIE 1492
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1493 ALEEELKK-----KNLENQeLIACRSDLSDLLKE-AQDARRTLENELAAVSHAKQVLSS-------SFNTCSSDIEILNR 1559
Cdd:TIGR04523  271 EKQKELEQnnkkiKELEKQ-LNQLKSEISDLNNQkEQDWNKELKSELKNQEKKLEEIQNqisqnnkIISQLNEQISQLKK 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1560 ERTELQDKCQKLTGEVENMKENLTVEKKarilDKESFLLERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSE 1639
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKK----ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1640 TKLEEVIKEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVM-------LDELQHKYEVTEKEKMELVQEN 1712
Cdd:TIGR04523  426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSinkikqnLEQKQKELKSKEKELKKLNEEK 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1713 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKVVALLEQTDADfscrllVSEGKHELLLEEMSNLALKLREIERLQAQ 1792
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD------DFELKKENLEKEIDEKNKEIEELKQTQKS 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1793 TFMQKFEADKRAEEVLQTMEKVTKEKdaihQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENK 1872
Cdd:TIGR04523  580 LKKKQEEKQELIDQKEKEKKDLIKEI----EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655


                   ....*...
gi 2024359622 1873 KVEELKKE 1880
Cdd:TIGR04523  656 EIRNKWPE 663
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 345-703 3.82e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 3.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  345 QEALK-EKQQHIEQLLAERDLERAEVAKAtshvGEIEQELALVRDgHDRHVLEMEAKMDQLRamveaadrekvellnqLE 423
Cdd:pfam17380  298 QERLRqEKEEKAREVERRRKLEEAEKARQ----AEMDRQAAIYAE-QERMAMERERELERIR----------------QE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  424 EEKRKVEdlqfRVEEESITkgdlerkrqisedpenvatvSEKSRIMELERDLALRVKEVAELRGRLESSKH--IDDVDTS 501
Cdd:pfam17380  357 ERKRELE----RIRQEEIA--------------------MEISRMRELERLQMERQQKNERVRQELEAARKvkILEEERQ 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  502 LSLLQEISSLQEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTK---LDHANKENSDVIEL 578
Cdd:pfam17380  413 RKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKkleLEKEKRDRKRAEEQ 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  579 WKSKLESAIASHQQAMEElkvsfnkgvgaQTAEFAELKTQMEKVKLDYENEMSNLKLKQENEKSQHLKEIEALKAKLLEV 658
Cdd:pfam17380  493 RRKILEKELEERKQAMIE-----------EERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKA 561

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 2024359622  659 TEEkeqtlenlKAKLESVEDQhlvemEDTLNKLQEAEIKVKELDV 703
Cdd:pfam17380  562 TEE--------RSRLEAMERE-----REMMRQIVESEKARAEYEA 593
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 1589-2015 3.97e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 42.63  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1589 RILDKESFLLERME-----------LQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIKEKMILYKETE 1657
Cdd:pfam15818    1 QLLDFKTSLLEALEelrmrreaetqYEEQIGKIIVETQELKWQKETLQNQKETLAKQHKEAMAVFKKQLQMKMCALEEEK 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1658 ---QLASK-----IEQLKSDFTSLSVSKAELEDVhscVSVMLDELQ----------------HKYEVTEKEKMELVQEN- 1712
Cdd:pfam15818   81 gkyQLATEikekeIEGLKETLKALQVSKYSLQKK---VSEMEQKLQlhllakedhhkqlneiEKYYATITGQFGLVKENh 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1713 ESLHAEWKSLVIINEEILKEKEKLSKEYYKLHEKvvalLEQTDADFSCRLLVSEGKHElllEEMSNLALKLREIERLQAQ 1792
Cdd:pfam15818  158 GKLEQNVQEAIQLNKRLSALNKKQESEICSLKKE----LKKVTSDLIKSKVTCQYKMG---EENINLTIKEQKFQELQER 230

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1793 TFMQkfeadkraeevLQTMEKVTKEKDAIHQEKIETLAS-------LENSRQTNEKLQNELDMLKQNN--LKNEEELTKS 1863
Cdd:pfam15818  231 LNME-----------LELNKKINEEITHIQEEKQDIIISfqhmqqlLQQQTQANTEMEAELKALKENNqtLERDNELQRE 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1864 K------ELLNLENKKVEEL---KKEFEALKLAAAQKSQQLAALQEENVKLAEElgrsRDEVTSHQKLEEERSVLNNQLL 1934
Cdd:pfam15818  300 KvkeneeKFLNLQNEHEKALgtwKKHVEELNGEINEIKNELSSLKETHIKLQEH----YNKLCNQKKFEEDKKFQNVPEV 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1935 EMKKS-LPSNTLRESTLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKL 2013
Cdd:pfam15818  376 NNENSeMSTEKSENLIIQKYNSEQEIREENTKSFCSDTEYRETEKKKGPPVEEIIIEDLQVLEKSFKNEIDTSVPQDKNQ 455


                   ..
gi 2024359622 2014 EE 2015
Cdd:pfam15818  456 SE 457
EzrA pfam06160
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...
 1799-1939 3.97e-03

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.


Pssm-ID: 428797 [Multi-domain]  Cd Length: 542  Bit Score: 42.15  E-value: 3.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1799 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1878
Cdd:pfam06160  267 EIEERIDQLYDLLEKEVDAKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENELERVRGL----EKQLEELE 342

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622 1879 KEFEALKLAAAQKSQ--------------QLAALQEENVKLAEELGRSR-DEVTSHQKLEEERSVLNNQLLEMKKS 1939
Cdd:pfam06160  343 KRYDEIVERLEEKEVayselqeeleeileQLEEIEEEQEEFKESLQSLRkDELEAREKLDEFKLELREIKRLVEKS 418
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
824-1166 4.60e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.81  E-value: 4.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  824 ENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMKM 903
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  904 NDELRLKERQLEQIQLELTKANEKAVQLQKNVEQtAQKAEQSQQETLKTHQEELKKMQDQLTDMKKQMETSQNQYKDLQA 983
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEELEE-LQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQE 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  984 KYEKETSEMITKHDADIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRDLI 1063
Cdd:COG4372    165 ELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALEL 244

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1064 SEKETLAQERNTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSRQESTEKVALISEK 1143
Cdd:COG4372    245 EEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLEL 324

                          330       340
                   ....*....|....*....|...
gi 2024359622 1144 SKLLSEIETAQADLLKITQENDA 1166
Cdd:COG4372    325 AKKLELALAILLAELADLLQLLL 347
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 831-1017 4.78e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  831 QETINKLNQKEEQFALMSSELEQLKSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLM--KMNDELR 908
Cdd:COG1579     13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGnvRNNKEYE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  909 LKERQLEQIQLELTKANEKAVQLQKNVEQtaqkaeqsqqetlktHQEELKKMQDQLTDMKKQMETSQNQYKDLQAKYEKE 988
Cdd:COG1579     93 ALQKEIESLKRRISDLEDEILELMERIEE---------------LEEELAELEAELAELEAELEEKKAELDEELAELEAE 157

                          170       180
                   ....*....|....*....|....*....
gi 2024359622  989 TSEMITKHDADIKGFKQNLLDAEEALKAA 1017
Cdd:COG1579    158 LEELEAEREELAAKIPPELLALYERIRKR 186
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 1799-1940 4.83e-03

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 42.13  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1799 EADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELlnleNKKVEELK 1878
Cdd:PRK04778   286 EIQERIDQLYDILEREVKARKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQL----EKQLESLE 361

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2024359622 1879 KEFEALKLAAAQKSQ---QLAALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEMKKSL 1940
Cdd:PRK04778   362 KQYDEITERIAEQEIaysELQEELEEILKQLEEIEKEQEKLSEMlQGLRKDELEAREKLERYRNKL 427
PLN02939 PLN02939
transferase, transferring glycosyl groups
 792-1159 5.30e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 42.20  E-value: 5.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  792 EKNLSAVNQVKDSLEKELQLLKEKFTSAVDGAENAQRamqeTINKLNQKEEQfAL-----MSSELEQLKSNLTVMETKLK 866
Cdd:PLN02939   106 EAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEK----NILLLNQARLQ-ALedlekILTEKEALQGKINILEMRLS 180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  867 EREEREQQLTEAKVKLEndiaeimkssgdssaqlmkmndelrLKERQLEQIQLELTK--ANEKAVQLQKNVEQTAQKAEQ 944
Cdd:PLN02939   181 ETDARIKLAAQEKIHVE-------------------------ILEEQLEKLRNELLIrgATEGLCVHSLSKELDVLKEEN 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  945 SqqeTLKTHQEELKKMQDQLTDMKKQMetsqnqykdlqAKYEKETSEMitkhDADIKGFKQNLLDAEEAL--------KA 1016
Cdd:PLN02939   236 M---LLKDDIQFLKAELIEVAETEERV-----------FKLEKERSLL----DASLRELESKFIVAQEDVsklsplqyDC 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1017 AQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKMRD-----LISEKETLAQERntLKLEKESLLSQHLEME 1091
Cdd:PLN02939   298 WWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEanvskFSSYKVELLQQK--LKLLEERLQASDHEIH 375

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2024359622 1092 SKILLVQQDREELWTKNEELNSENKKILKQKEAAEAKSrqESTEKVALISEKSKLLSEIETAQADLLK 1159
Cdd:PLN02939   376 SYIQLYQESIKEFQDTLSKLKEESKKRSLEHPADDMPS--EFWSRILLLIDGWLLEKKISNNDAKLLR 441
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 922-1041 5.69e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 41.25  E-value: 5.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  922 TKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQLTDMkkqmetsQNQYKDLQAKYEKETsemitkhdadik 1001
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATA-------QKELANAQAQALQTA------------ 316

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 2024359622 1002 gfKQNLLDAEEALKAAQKKNDELETQAEELK-KQAEQAKSL 1041
Cdd:TIGR04320  317 --QNNLATAQAALANAEARLAKAKEALANLNaDLAKKQAAL 355
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 538-771 5.84e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 5.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  538 EALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVIELWKsKLESAIASHQQAMEELKVSFNKGVGAQTAEFAELKT 617
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAELAELEKEIAELRAELEAQKEELAE 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  618 QMEKVKLDYENEMSNLKLKQENeKSQHLKEIEALKAkLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIK 697
Cdd:COG4942    109 LLRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKY-LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024359622  698 VKELDVLQAkcnEQTKLIGSLTQQIRASEEKlldLAALQKANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGS 771
Cdd:COG4942    187 RAALEALKA---ERQKLLARLEKELAELAAE---LAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGK 254
PRK11281 PRK11281
mechanosensitive channel MscK;
979-1282 6.25e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  979 KDLQAKYEKETSemITKHDADIKGFKQNLLDAEEALKAAQKKNDELEtqaeELKKQAEQAKSLssvLASARKEIELMSDk 1058
Cdd:PRK11281    39 ADVQAQLDALNK--QKLLEAEDKLVQQDLEQTLALLDKIDRQKEETE----QLKQQLAQAPAK---LRQAQAELEALKD- 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1059 mrdliSEKETLAQERNTLKLEkesllsqhlEMESKILLVQQDREELwtkNEELNSENKKILKQkeaaeaksrQESTEKV- 1137
Cdd:PRK11281   109 -----DNDEETRETLSTLSLR---------QLESRLAQTLDQLQNA---QNDLAEYNSQLVSL---------QTQPERAq 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1138 ALISEKSKLLSEIETaqadLLKITQEND-ALRSSESTLLQ------------QLKELQANKDAVDVACQKHIKEREE--- 1201
Cdd:PRK11281   163 AALYANSQRLQQIRN----LLKGGKVGGkALRPSQRVLLQaeqallnaqndlQRKSLEGNTQLQDLLQKQRDYLTARiqr 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1202 LEHYQKLLEE--NDRVIKDKDDVIQRLQSSyDDLARNQ--RELLQEVSILTAERD---SAQEKDLDLKSTHIALKNEIDC 1274
Cdd:PRK11281   239 LEHQLQLLQEaiNSKRLTLSEKTVQEAQSQ-DEAARIQanPLVAQELEINLQLSQrllKATEKLNTLTQQNLRVKNWLDR 317


                   ....*...
gi 2024359622 1275 LLQTNRSL 1282
Cdd:PRK11281   318 LTQSERNI 325
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 397-701 6.38e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.45  E-value: 6.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  397 MEAKMDQLRAMveAADREKVELLNQL-EEEKRKVEDLQFRVEEESITKgDLERKRQISEDPENVATVSEKSRImELERDL 475
Cdd:PRK05771     2 APVRMKKVLIV--TLKSYKDEVLEALhELGVVHIEDLKEELSNERLRK-LRSLLTKLSEALDKLRSYLPKLNP-LREEKK 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  476 ALRVKEVAELRGRLES--SKHIDDVDtslSLLQEISSLQEKMaaagKEHQREMSSLK--EKFESSEEALRKEiKTLSASN 551
Cdd:PRK05771    78 KVSVKSLEELIKDVEEelEKIEKEIK---ELEEEISELENEI----KELEQEIERLEpwGNFDLDLSLLLGF-KYVSVFV 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  552 ERMGKENESLktklDHANKENSDVIELWKSKLES--AIASHQQAMEELkvsfnkgvgaqtaeFAELKtqmekvkldyENE 629
Cdd:PRK05771   150 GTVPEDKLEE----LKLESDVENVEYISTDKGYVyvVVVVLKELSDEV--------------EEELK----------KLG 201

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2024359622  630 MSNLKLKQENEKSQhlkEIEALKAKLLEVTEEKEQTLENLKAKLESVEDQHLVEMEDTLNKLQEAEIKVKEL 701
Cdd:PRK05771   202 FERLELEEEGTPSE---LIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEALSKFL 270
PRK12704 PRK12704
phosphodiesterase; Provisional
 735-891 6.47e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 6.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  735 LQKANSEGKlEIQKlsEQLQAAEKQIQNL--ETEKvggssKVSNLTKELQGKEQKLLDLEKNlsavnqvkdsLEKELQLL 812
Cdd:PRK12704    44 LEEAKKEAE-AIKK--EALLEAKEEIHKLrnEFEK-----ELRERRNELQKLEKRLLQKEEN----------LDRKLELL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  813 KEKftsavdgaenaQRAMQETINKLNQKEEQFALMSSELEQLKSN-LTVME--TKLKEREEREQQLTEAKVKLENDIAEI 889
Cdd:PRK12704   106 EKR-----------EEELEKKEKELEQKQQELEKKEEELEELIEEqLQELEriSGLTAEEAKEILLEKVEEEARHEAAVL 174


                   ..
gi 2024359622  890 MK 891
Cdd:PRK12704   175 IK 176
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1574-2083 7.73e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 41.26  E-value: 7.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1574 EVENMKENLTVEKKARILDKESfllERMELQNNIGFLEKEVEEMREKNKEFLTEKELLVQEKEKSETKLEEVIkEKMILY 1653
Cdd:pfam05557    6 ESKARLSQLQNEKKQMELEHKR---ARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQA-ELNRLK 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1654 KETEQLASKIEQLKSDftslsvSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLhaewkslviinEEILKEK 1733
Cdd:pfam05557   82 KKYLEALNKKLNEKES------QLADAREVISCLKNELSELRRQIQRAELELQSTNSELEEL-----------QERLDLL 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1734 EKLSKEYYKLHEkvvalleqtdadfscrllvsegKHELLLEEMSNLALKLREIERlQAQTFMQKFEADKRAEEVLQTMEK 1813
Cdd:pfam05557  145 KAKASEAEQLRQ----------------------NLEKQQSSLAEAEQRIKELEF-EIQSQEQDSEIVKNSKSELARIPE 201

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1814 VTKEKDAIHQEKietlASLENSRQTNEKLQNELDMLKQnNLKNEEELTKSKELLNLENKKVEELKKEFEALKLAAAQK-- 1891
Cdd:pfam05557  202 LEKELERLREHN----KHLNENIENKLLLKEEVEDLKR-KLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlr 276

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1892 -----SQQLAALQEENVKLAEELG----RSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNT-------LRESTLKKEID 1955
Cdd:pfam05557  277 spedlSRRIEQLQQREIVLKEENSsltsSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKalvrrlqRRVLLLTKERD 356

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1956 EERASLQK-----SISDTSALITQKDEELEKLRNEITVLRGEnasaktLQSVVKTLESDKLKLEEKVKNLEQKLKAKSEQ 2030
Cdd:pfam05557  357 GYRAILESydkelTMSNYSPQLLERIEEAEDMTQKMQAHNEE------MEAQLSVAEEELGGYKQQAQTLERELQALRQQ 430

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2024359622 2031 PLTVTSPSgdiaanllQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMC 2083
Cdd:pfam05557  431 ESLADPSY--------SKEEVDSLRRKLETLELERQRLREQKNELEMELERRC 475
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1030-1266 8.24e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 8.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1030 ELKKQAEQAKSLSSVLASARKeIELMSDKMRDLISEKETLAQERNTLKLEKESLLSQHLEmeSKILLVQQDREELWTKNE 1109
Cdd:PRK05771    34 EDLKEELSNERLRKLRSLLTK-LSEALDKLRSYLPKLNPLREEKKKVSVKSLEELIKDVE--EELEKIEKEIKELEEEIS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1110 ELNSENKKILKQKEAAE----------AKSRQESTE-KVALISEKSKLLSEIETAQADLLKITQEND-------ALRSSE 1171
Cdd:PRK05771   111 ELENEIKELEQEIERLEpwgnfdldlsLLLGFKYVSvFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvVLKELS 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1172 STLLQQLKELQAnkDAVDVACQKHIKEReeLEHYQKLLEENDRVIKDKDDVIQRLQSSYDDLARNQRELlqevsiLTAER 1251
Cdd:PRK05771   191 DEVEEELKKLGF--ERLELEEEGTPSEL--IREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIEL 260

                          250
                   ....*....|....*
gi 2024359622 1252 DSAQEKDLDLKSTHI 1266
Cdd:PRK05771   261 ERAEALSKFLKTDKT 275
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
355-556 8.85e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  355 IEQLLAERDLERAEVAKATShvGEIEQELALVRDghdrHVLEMEAKMDQLRA---MVEAADREKVeLLNQLEEEKRKVED 431
Cdd:COG3206    158 AEAYLEQNLELRREEARKAL--EFLEEQLPELRK----ELEEAEAALEEFRQkngLVDLSEEAKL-LLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  432 LQFRVEEESITKGDLERkrQISEDPENVATVSEKSRIMELERDLALRVKEVAELRGRLeSSKHIDDVdtslSLLQEISSL 511
Cdd:COG3206    231 ARAELAEAEARLAALRA--QLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARY-TPNHPDVI----ALRAQIAAL 303

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 2024359622  512 QEKMAAAGKEHQREMSSLKEKFESSEEALRKEIKTLSASNERMGK 556
Cdd:COG3206    304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE 348
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1490-2107 9.31e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.11  E-value: 9.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1490 SIEALEEELKKKNLENQELIACRSDLSDLLKEAQDARRTLENELAAVSHAKQVLSSSFNTCSSDIEILNRE---RTELQD 1566
Cdd:pfam02463  189 IIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEiekEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1567 KCQKLTGEVENMKENLTVEKKARILDKESFLLERMELQNNIGFLEKEVEEMREKNKEfltekelLVQEKEKSETKLEEVI 1646
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK-------AEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1647 KEKMILYKETEQLASKIEQLKSDFTSLSVSKAELEDVHSCVSVMLDELQHKYEVTEKEKMELVQENESLHAEWKSLVIIN 1726
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1727 EEILKEK------EKLSKEYYKLHEKVVALLEQTDADFSCRLLVSEGKHELLLEEMSNLALKLREIERLQAQ-----TFM 1795
Cdd:pfam02463  422 KEEKKEEleileeEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQkleerSQK 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1796 QKFEADKRAEEVLQTMEKVTKEKDAIHQEKIETLASLENSRQTNEKLQNELDMLKQNNLKNEEELTKSKELLNLENKKVE 1875
Cdd:pfam02463  502 ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLR 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1876 ELKKEFEALKLAAAQKS--------QQLAALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKSLPSNTLRE 1947
Cdd:pfam02463  582 LLIPKLKLPLKSIAVLEidpilnlaQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1948 STLKKEIDEERASLQKSISDTSALITQKDEELEKLRNEITVLRGENASAKTLQSVVKTLESDKLKLEEKVKNLEQKLKAK 2027
Cdd:pfam02463  662 SEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLL 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 2028 S------EQPLTVTSPSGDIAANLLQDESAEDKQQEIDFLNSVIVDLQRRNEELNLKIQRMCEAALNGNEEETINYDSEE 2101
Cdd:pfam02463  742 KqkideeEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQ 821


                   ....*.
gi 2024359622 2102 EGLSKK 2107
Cdd:pfam02463  822 LLIEQE 827
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 525-1523 9.43e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.19  E-value: 9.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  525 EMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANK--------ENSDVIELWKSKLESAIASHQQAMEE 596
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDvadkaisnDDPEEIEKKIENIVTKIDKKKNIYDE 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  597 LKVSFNkgvgaQTAEFAELKTQMEKVK---LDYENEMSNLKLKQ---ENEKSQHLkeIEALKAKLlevteekeQTLENLK 670
Cdd:TIGR01612 1192 IKKLLN-----EIAEIEKDKTSLEEVKginLSYGKNLGKLFLEKideEKKKSEHM--IKAMEAYI--------EDLDEIK 1256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  671 AKLESVEDQHLVEMEDT--LNKLQEAEIKVKELDVLQAKCNEQTKLIGSLTQQIRASEEKLLDLAALQKANSEGKLEIQK 748
Cdd:TIGR01612 1257 EKSPEIENEMGIEMDIKaeMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQK 1336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  749 LSEQLQAAEKQIQNL-ETEKVGGSSKVSNLTKELQGKEQKL-----LDLEKNLSAVNQVKDSLEkeLQLLKEKFTSAVDG 822
Cdd:TIGR01612 1337 HNSDINLYLNEIANIyNILKLNKIKKIIDEVKEYTKEIEENnknikDELDKSEKLIKKIKDDIN--LEECKSKIESTLDD 1414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  823 AEnaqraMQETINKLnqKEEQFALMSSEleqlkSNLTVMETKLKEREEREQQLTEAKVKLENDIAEIMKSSGDSSAQLMK 902
Cdd:TIGR01612 1415 KD-----IDECIKKI--KELKNHILSEE-----SNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHD 1482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  903 MN-DELRLKERQLEQIQlelTKANEKAVQLQKNVEQTAQKAEQSQQETLKTHQEELKKMQDQltdMKKQMETSQNQYKDL 981
Cdd:TIGR01612 1483 FNiNELKEHIDKSKGCK---DEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAK---TKKDSEIIIKEIKDA 1556

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  982 QAKY--EKETSEMITKhdaDIKGFKQNLLDAEEALKAAQKKNDELETQAEELKKQAEQAKSLSSVLASARKEIELMSDKM 1059
Cdd:TIGR01612 1557 HKKFilEAEKSEQKIK---EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKI 1633

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1060 RDL-ISEKETLAQER----NTLKLEKESLLSQHLEMESKILLVQQDREELWTKNEELNSENKK-----ILKQKEAAEAKS 1129
Cdd:TIGR01612 1634 SSFsIDSQDTELKENgdnlNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNyeigiIEKIKEIAIANK 1713

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1130 RQESTEKVALISEKSKLLSEIETAqaDLLKI----------TQENDALR----------------SSESTLLQQLKELQA 1183
Cdd:TIGR01612 1714 EEIESIKELIEPTIENLISSFNTN--DLEGIdpnekleeynTEIGDIYEefielyniiagcletvSKEPITYDEIKNTRI 1791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1184 NkdavdvACQKHIKEREELEHYQKLLE-----ENDRVI----KDKDDVIQRLQSSYDDLARNQRELLQEVSILTAERDSA 1254
Cdd:TIGR01612 1792 N------AQNEFLKIIEIEKKSKSYLDdieakEFDRIInhfkKKLDHVNDKFTKEYSKINEGFDDISKSIENVKNSTDEN 1865

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1255 QEKDLdLKSTHIALKNEIDcllQTNRSLQSEKEMLLKSREELCVSLANTANENQALKLRKD---EMQTELETEREKLEKM 1331
Cdd:TIGR01612 1866 LLFDI-LNKTKDAYAGIIG---KKYYSYKDEAEKIFINISKLANSINIQIQNNSGIDLFDNiniAILSSLDSEKEDTLKF 1941

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1332 TKDNMDLKASLSSLSN----FLEEMKSSREASNSEKihllQEALFASEQRLLAEREELVNENKAVTEKlTKATADAVLAE 1407
Cdd:TIGR01612 1942 IPSPEKEPEIYTKIRDsydtLLDIFKKSQDLHKKEQ----DTLNIIFENQQLYEKIQASNELKDTLSD-LKYKKEKILND 2016

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622 1408 TAFT-EKINELN------------LE---KESVFSKSLQFEKHNEALLREKD--ELERKYSELLDEKKSLENAFSDMKRE 1469
Cdd:TIGR01612 2017 VKLLlHKFDELNklscdsqnydtiLElskQDKIKEKIDNYEKEKEKFGIDFDvkAMEEKFDNDIKDIEKFENNYKHSEKD 2096

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....
gi 2024359622 1470 QELDFSAKRLLVQENTTLKYSIEALEEELKKknLENQelIACRSDLSDLLKEAQ 1523
Cdd:TIGR01612 2097 NHDFSEEKDNIIQSKKKLKELTEAFNTEIKI--IEDK--IIEKNDLIDKLIEMR 2146
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 342-664 9.46e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 9.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  342 TALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALVRDGHDRHVLEMEAKMDQLRAMVEAADReKVELLNQ 421
Cdd:pfam05483  460 TAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEER-MLKQIEN 538

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  422 LEEEKRKVEDLQFRVEEESITKGDlERKRQISEDPENVATVseKSRIMELERDLALRVKEVAELRGRLES-SKHIDDVDT 500
Cdd:pfam05483  539 LEEKEMNLRDELESVREEFIQKGD-EVKCKLDKSEENARSI--EYEVLKKEKQMKILENKCNNLKKQIENkNKNIEELHQ 615

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  501 SLSLLQEISSLQEKMAAAGK----EHQREMSSLKEKFESSEEALRKEIKTLSASNERMGKENESLKTKLDHANKENSDVI 576
Cdd:pfam05483  616 ENKALKKKGSAENKQLNAYEikvnKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEID 695

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  577 ELWKSKLESAIAshqqAMEELKVSFNKGVGAQTAEFAELKTQmekvkldyENEMSNLKLKQENEKSQHLKEIEALKAKLL 656
Cdd:pfam05483  696 KRCQHKIAEMVA----LMEKHKHQYDKIIEERDSELGLYKNK--------EQEQSSAKAALEIELSNIKAELLSLKKQLE 763


                   ....*...
gi 2024359622  657 EVTEEKEQ 664
Cdd:pfam05483  764 IEKEEKEK 771
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 737-1074 9.52e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 40.99  E-value: 9.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  737 KANSEGKLEIQKLSEQLQAAEKQIQNLETEKVGGSSKVSNLTKElqgKEQKLLDLEKNLSAVNQvkdSLEKELQLLKEKF 816
Cdd:PLN03229   422 KKREAVKTPVRELEGEVEKLKEQILKAKESSSKPSELALNEMIE---KLKKEIDLEYTEAVIAM---GLQERLENLREEF 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  817 TSAVDGAENAQRAMQETINKLNQKEEQFALMSSELEQLKSNLtvmeTKLKEReEREQQLTEAKVKLENDIAEIMKssgds 896
Cdd:PLN03229   496 SKANSQDQLMHPVLMEKIEKLKDEFNKRLSRAPNYLSLKYKL----DMLNEF-SRAKALSEKKSKAEKLKAEINK----- 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  897 saQLMKMNDELRLKERqLEQIQLELTKAN-EKAVQLQKNVEQTAQKAEQSQQETLKthqEELKKMQDQLTDM-KKQMETS 974
Cdd:PLN03229   566 --KFKEVMDRPEIKEK-MEALKAEVASSGaSSGDELDDDLKEKVEKMKKEIELELA---GVLKSMGLEVIGVtKKNKDTA 639

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  975 QNQ-YKDLQAKYEK---ETSEMITK--HDADIKGfKQNLLDAEEAlKAAQKKNDELETQAEELKKQAEQakSLSSVLASA 1048
Cdd:PLN03229   640 EQTpPPNLQEKIESlneEINKKIERviRSSDLKS-KIELLKLEVA-KASKTPDVTEKEKIEALEQQIKQ--KIAEALNSS 715

                          330       340
                   ....*....|....*....|....*.
gi 2024359622 1049 rkEIELMSDKMRDLISEKETLAQERN 1074
Cdd:PLN03229   716 --ELKEKFEELEAELAAARETAAESN 739
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 744-918 9.81e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 40.97  E-value: 9.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  744 LEIQK---LSEQL-QAAEKQIQNlETEKVGGS-SKVSNLTKELqgkEQKLLDLEKNLSAVNQVKDSLEKELQLLKEKFTS 818
Cdd:PRK00409   491 FEIAKrlgLPENIiEEAKKLIGE-DKEKLNELiASLEELEREL---EQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDK 566

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024359622  819 AVDGAE--------NAQRAMQETINKLN--QKEEQFALMSSELE----QLKSNLTVMETKLKEREEREQQLT---EAKVK 881
Cdd:PRK00409   567 LLEEAEkeaqqaikEAKKEADEIIKELRqlQKGGYASVKAHELIearkRLNKANEKKEKKKKKQKEKQEELKvgdEVKYL 646

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 2024359622  882 LENDIAEIMKSSGDSSAQ----LMKMndelRLKERQLEQIQ 918
Cdd:PRK00409   647 SLGQKGEVLSIPDDKEAIvqagIMKM----KVPLSDLEKIQ 683
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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